Hub : Genes

Tcf12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Tcf12 0.13 0.09 3.4e-09 0.1 0.11 0.11 0.11 2.5e-09 5.0e-10 4.3e-10 4.5e-10
2 PL alternative polyA XM_039080905.1 0.03 0.02 8.8e-03 0.01 0.01 0.01 0.01 2.5e-02 1.9e-02 2.7e-02 1.9e-02
3 Adipose gene expression Tcf12 0.03 0.03 2.4e-03 0.01 0.01 0 0.01 3.7e-02 2.6e-02 1.1e-01 3.6e-02
4 Adipose mRNA stability Tcf12 0.03 0.02 3.1e-03 0 0 0 0 2.8e-01 9.3e-02 2.4e-01 2.9e-01
5 NAcc gene expression Tcf12 0.13 0.11 1.8e-10 0.09 0.09 0.09 0.1 6.9e-11 1.1e-10 3.3e-10 3.5e-11
6 pVTA gene expression Tcf12 0.07 0.06 5.5e-03 0.01 -0 -0 -0 1.1e-01 5.0e-01 4.9e-01 4.3e-01
7 PL mRNA stability Tcf12 0.03 0.02 5.4e-03 0.01 0.01 0.02 0.01 1.5e-02 1.9e-02 2.9e-03 5.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.30.40.7-0.1-0.00.8-0.60.8-0.80.8
Area under the delay curve1.11.12.20.91.00.5-1.51.1-1.11.1
BMI with tail2.78.720.74.54.6-3.5-2.5-0.60.6-0.1
BMI without tail1.22.56.21.51.7-2.50.1-1.61.6-1.0
Body weight2.39.824.14.94.9-3.3-3.1-0.10.10.3
Weight adjusted by age3.64.18.22.01.9-2.90.0-2.02.0-2.1
Bone surface0.10.10.30.50.5-0.4-0.3-0.10.1-0.1
Bone volume0.10.10.30.40.5-0.1-0.50.2-0.20.3
Breakpoint value in progressive ratio session0.20.20.40.60.5-0.2-0.40.2-0.20.6
Number of licking bursts1.11.33.2-1.7-1.81.01.3-0.20.2-0.1
Context. condit. distance diff. score0.70.81.4-0.4-0.21.1-0.61.2-1.20.9
Locomotion velocity, session 12.52.74.80.10.1-1.81.3-2.12.1-2.2
Locomotion distance, session 10.60.81.3-1.1-1.10.21.1-0.60.6-0.9
Locomotion velocity, session 20.30.30.70.00.2-0.70.4-0.80.8-0.5
Locomotion distance, session 20.40.50.9-0.1-0.0-0.70.6-1.01.0-0.9
Locomotion velocity, session 32.73.15.1-1.5-1.5-0.62.2-1.91.9-2.3
Locomotion distance, session 31.21.33.2-1.8-1.71.31.00.2-0.2-0.1
Stereotopy head waving bouts, day 30.40.40.70.50.4-0.90.2-0.80.8-0.8
Stereotopy head waving duration, day 30.60.71.20.50.5-1.10.3-1.01.0-0.9
Locomotion velocity, session 70.80.92.4-1.6-1.41.10.80.2-0.20.0
Locomotion distance, session 71.11.43.4-1.8-1.80.91.3-0.30.3-0.7
Stereotopy head waving bouts, day 70.80.91.70.30.2-1.20.7-1.31.3-0.9
Stereotopy head waving duration, day 71.31.52.90.0-0.0-1.41.1-1.71.7-1.4
Locomotion velocity, session 80.60.71.3-0.10.0-1.00.7-1.21.2-0.8
Locomotion distance, session 80.20.20.8-0.9-0.60.60.30.2-0.20.2
Degree of sensitization distance0.10.10.1-0.4-0.40.10.3-0.20.2-0.1
Degree of sensitization stereotypy0.60.61.20.30.2-1.00.6-1.11.1-0.7
Conditioned locomotion1.01.12.20.81.00.5-1.51.2-1.21.0
Cocaine response after cond. corrected1.41.63.60.90.8-1.90.5-1.51.5-1.1
Cocaine response after cond. not corrected0.80.91.90.50.6-1.40.4-1.21.2-0.9
Cocaine response before conditioning0.70.81.6-0.5-0.31.3-0.61.2-1.20.8
Saline control response1.01.32.2-1.3-1.2-0.11.5-1.11.1-1.2
Bone: connectivity density0.40.61.5-1.1-1.21.00.70.1-0.0-0.2
Bone: cortical apparent density0.30.40.9-1.0-0.90.70.60.1-0.10.1
Bone: cortical area0.00.00.10.10.20.0-0.30.2-0.2-0.1
Bone: cortical porosity0.70.81.3-0.4-0.31.1-0.61.1-1.01.1
Bone: cortical porosity1.61.73.0-0.4-0.31.6-1.01.6-1.61.7
Bone: cortical thickness0.50.81.8-0.9-0.91.3-0.00.8-0.80.7
Bone: cortical thickness0.30.40.9-0.9-0.90.90.40.3-0.30.0
Bone: cortical tissue density0.30.41.0-1.0-0.90.70.60.1-0.10.1
Condit. Reinf. active minus inactive responses2.02.34.21.01.10.7-1.91.7-1.72.1
Condit. Reinf. active-inactive response ratio2.32.54.30.50.61.3-1.72.0-2.02.1
Condit. Reinf. active responses0.60.71.50.91.0-0.1-1.00.6-0.61.2
Condit. Reinf. inactive responses1.01.22.4-0.0-0.1-1.21.1-1.51.5-1.0
Incentive salience index mean2.22.64.41.21.40.7-2.11.8-1.72.0
Condit. Reinf. lever presses1.01.32.40.80.90.6-1.61.3-1.31.3
Condit. Reinf. active minus inactive responses1.51.94.72.12.2-1.5-1.3-0.10.20.3
Condit. Reinf. active-inactive response ratio0.70.81.91.31.4-0.9-0.9-0.00.00.5
Condit. Reinf. active responses1.42.04.82.02.2-0.9-1.80.5-0.50.7
Condit. Reinf. inactive responses0.60.71.30.60.70.5-1.11.0-1.00.8
Condit. Reinf. lever presses0.40.50.9-0.3-0.20.9-0.50.9-0.90.9
Condit. Reinf. lever reinforcers received1.31.83.91.82.0-0.6-1.80.8-0.80.9
Conditioned reinforcement - actives0.20.20.3-0.5-0.5-0.00.6-0.50.5-0.4
Conditioned reinforcement - inactives0.30.30.5-0.7-0.60.10.7-0.50.60.2
Conditioned locomotion1.51.83.00.40.51.2-1.51.7-1.71.5
Patch foraging indifference point 0 sec0.61.03.0-0.2-0.2-0.91.0-1.01.0-1.7
Patch foraging indifference point AUC0.50.51.20.40.30.6-0.80.8-0.81.1
Delay disc. indifference point, 0s delay0.80.92.20.10.20.9-0.91.1-1.11.5
Delay disc. indifference point, 16s delay1.31.32.50.30.51.0-1.41.6-1.61.1
Delay disc. indifference point, 2s delay0.10.10.3-0.4-0.40.50.10.2-0.20.4
Delay disc. indifference point, 24s delay0.40.40.9-0.00.00.6-0.50.7-0.71.0
Delay disc. indifference point, 4s delay1.31.42.30.40.51.0-1.31.4-1.41.5
Delay disc. indifference point, 8s delay0.60.61.21.11.1-0.3-1.00.4-0.40.6
Indifference point function ln k0.70.92.00.40.3-1.30.6-1.11.1-1.4
Indifference point function log k0.70.92.00.40.3-1.30.6-1.11.1-1.4
Patch foraging total patch changes 0 sec0.71.23.5-0.1-0.2-1.11.0-1.21.2-1.9
Patch foraging total patch changes 12 sec0.10.10.2-0.3-0.40.50.10.3-0.30.1
Patch foraging total patch changes 18 sec0.10.10.3-0.1-0.1-0.10.2-0.20.2-0.5
Patch foraging total patch changes 24 sec0.40.51.1-0.3-0.4-0.40.8-0.90.9-1.1
Patch foraging total patch changes 6 sec0.00.10.20.30.2-0.40.1-0.20.2-0.3
Patch foraging time to switch 0 sec0.91.32.5-1.1-1.01.6-0.11.2-1.21.3
Patch foraging water rate 0 sec1.52.44.51.41.3-2.10.1-1.61.6-1.9
Patch foraging water rate 12 sec2.94.58.11.21.0-2.81.0-2.52.6-2.6
Patch foraging water rate 18 sec0.50.61.20.20.3-0.90.4-1.01.0-1.1
Patch foraging water rate 24 sec0.50.61.1-0.3-0.4-0.50.8-1.01.0-1.1
Patch foraging water rate 6 sec0.81.12.00.80.7-1.40.3-1.21.2-1.3
Seeking ratio, delayed vs. immediate footshock0.40.51.11.00.9-0.9-0.3-0.50.50.1
Distance traveled before self-admin0.00.00.00.10.1-0.1-0.10.1-0.1-0.1
Distance traveled after self-admin1.21.32.40.50.3-1.60.8-1.51.5-1.2
Extensor digitorum longus weight3.513.628.75.45.3-5.0-2.3-1.71.7-1.4
Bone: elastic displacement0.30.40.80.90.8-0.3-0.70.4-0.40.2
Bone: elastic work1.11.42.41.01.10.4-1.61.4-1.41.2
Bone: endosteal estimation1.02.34.81.71.8-2.2-0.4-1.21.2-1.3
Bone: endosteal perimeter1.63.37.92.72.8-2.2-1.5-0.40.4-0.7
Epididymis fat weight0.20.40.8-0.2-0.3-0.60.8-0.90.9-0.5
Delta time in closed arm before/after self-admin0.20.10.30.50.6-0.3-0.50.2-0.20.2
Delta time in open arm before/after self-admin1.71.64.0-2.0-1.90.81.6-0.40.4-0.4
Diff in mean of infusions in LGA sessions1.31.43.11.31.5-0.0-1.71.1-1.10.7
Delay discount exponential model param0.80.81.7-0.8-0.9-0.31.3-0.90.9-0.9
Extinction: sum of active levers before priming1.31.32.8-1.2-1.4-0.11.7-1.01.0-0.9
Active lever presses in extinction session 60.00.00.2-0.1-0.1-0.00.2-0.00.00.5
Bone: final force0.40.71.61.31.2-0.6-1.00.3-0.30.4
Bone: final moment0.30.51.01.01.0-0.2-1.00.5-0.50.5
Food consumed during 24 hour testing period1.41.73.90.10.1-1.41.0-1.51.5-2.0
Glucose0.40.71.20.40.3-1.00.5-1.11.1-0.9
Heart weight1.31.83.31.61.8-0.3-1.81.1-1.11.1
Delay discount hyperbolic model param0.60.61.2-0.6-0.6-0.41.1-0.90.9-0.8
Intermittent access intake day 1-15 change2.12.13.8-1.6-1.70.01.9-1.41.5-1.1
Intermittent access intake escalation2.32.34.2-1.7-1.80.12.0-1.51.5-0.9
Intermittent access intake escalation 21.01.01.6-0.7-0.8-0.41.2-1.21.3-1.0
Intermitt. access day 1 inactive lever presses0.40.40.9-1.0-1.00.60.60.0-0.00.4
Intermitt. access day 15 inactive lever presses0.91.02.70.60.70.5-1.21.0-0.91.6
Intermitt. access escalation Index1.41.23.01.71.7-1.1-1.10.1-0.10.4
Intermittent access day 1 total infusions0.60.71.8-1.4-1.20.70.8-0.10.10.4
Intermittent access day 15 total infusions1.71.94.4-2.1-2.10.91.7-0.70.7-0.1
Intermittent access terminal intake (last 3 days)0.80.92.2-1.5-1.41.10.70.1-0.10.4
Intermittent access total infusions2.12.34.3-2.1-2.10.42.0-1.11.1-0.8
Intermittent access day 1 locomotion1.01.02.5-1.6-1.41.30.60.5-0.50.6
Intermittent access day 15 total locomotion0.40.51.0-1.0-0.91.00.30.4-0.30.4
Intermittent access total locomotion0.40.40.8-0.8-0.7-0.00.9-0.60.6-0.5
Intermittent access standard deviation1.21.32.5-1.6-1.60.51.5-0.70.7-1.0
Left kidney weight1.13.16.52.62.4-2.4-0.9-1.11.1-0.5
Right kidney weight1.02.76.42.52.5-1.9-1.4-0.30.40.4
Cocaine induced anxiety0.30.40.6-0.4-0.20.8-0.40.8-0.80.6
Post-drug Anxiety0.80.92.0-1.1-1.01.40.10.9-0.90.7
Baseline Anxiety0.10.10.4-0.5-0.60.30.5-0.10.10.0
Tail length0.51.52.3-1.0-0.8-0.71.5-1.51.5-1.3
Length with tail0.31.12.71.51.6-1.3-0.9-0.30.2-0.2
Length without tail2.24.810.63.33.1-1.1-2.81.2-1.21.0
Times rat made contact with spout0.20.30.5-0.6-0.70.20.7-0.30.3-0.7
Lifetime Intake1.71.94.1-2.0-2.00.61.8-0.90.9-0.5
Liver weight, left1.21.93.40.20.2-1.81.1-1.91.8-1.5
Liver weight, right1.11.94.31.01.1-2.10.3-1.51.5-1.3
Locomotor activity2.03.26.32.52.4-2.5-0.8-1.01.0-1.0
Locomotor testing distance1.11.94.31.91.7-2.1-0.4-0.90.9-0.9
Locomotor testing rearing0.60.92.21.51.3-1.3-0.5-0.40.4-0.1
Locomotion in novel chamber0.50.61.2-1.1-1.01.10.40.5-0.50.5
Locomotion in novel chamber post-restriction0.70.92.80.20.30.6-0.81.0-1.01.7
Fecal boli incidents, locomotor time 10.30.40.80.10.30.6-0.70.9-0.90.1
Change in fecal boli incidents, locomotor task1.41.42.40.20.0-1.31.0-1.51.5-1.4
Time >=10cm from walls, locomotor time 10.40.40.80.80.8-0.0-0.90.5-0.5-0.3
Bouts of movement, locomotor time 10.20.20.40.40.4-0.6-0.0-0.50.5-0.5
Total resting periods, locomotor time 10.20.20.40.10.2-0.50.2-0.50.5-0.6
Rest time, locomotor task time 10.10.10.4-0.4-0.30.10.2-0.10.1-0.6
Distance moved, locomotor task time 10.10.10.4-0.4-0.50.20.4-0.10.10.6
Vertical activity count, locomotor time 10.30.31.50.10.10.3-0.40.5-0.51.2
Time >=10cm from walls, locomotor time 20.10.10.70.20.3-0.1-0.3-0.00.0-0.9
Bouts of movement, locomotor time 20.70.81.40.70.6-1.20.2-0.91.0-1.2
Total resting periods, locomotor time 20.91.01.70.60.5-1.30.5-1.21.2-1.2
Rest time, locomotor task time 20.10.10.4-0.6-0.60.30.40.1-0.10.1
Distance moved, locomotor task time 20.20.20.5-0.2-0.3-0.30.6-0.70.7-0.4
Vertical activity count, locomotor time 20.50.61.3-1.2-1.20.50.9-0.30.3-0.2
Light reinforcement 11.93.59.13.02.8-1.9-1.80.2-0.2-0.3
Light reinforcement 20.20.20.5-0.6-0.70.60.30.3-0.3-0.5
Bone: marrow area1.12.34.91.81.8-2.2-0.4-1.21.2-1.3
Bone: maximum diameter1.01.83.51.51.5-1.9-0.4-1.01.0-1.5
Bone: maximum force0.61.12.41.51.6-0.7-1.30.4-0.40.6
Bone: maximum moment0.50.81.71.21.3-0.3-1.20.6-0.60.7
Mean time between licks in bursts0.30.51.50.3-0.00.7-0.50.7-0.71.2
Mean num. licks in bursts0.50.61.21.01.1-1.0-0.5-0.30.3-0.6
Cd content in liver0.80.91.40.60.70.4-1.11.1-1.11.2
Co content in liver1.92.23.51.11.30.6-1.91.7-1.71.7
Cu content in liver1.01.22.11.31.4-0.2-1.50.9-0.91.0
Fe content in liver1.41.73.0-1.7-1.70.31.7-1.01.0-1.0
K content in liver0.80.82.01.41.3-1.1-0.7-0.20.2-0.4
Mg content in liver1.92.04.82.22.1-1.6-1.2-0.20.2-0.7
Mn content in liver0.30.30.70.60.70.0-0.80.5-0.50.2
Na content in liver1.21.32.70.90.7-1.50.3-1.21.2-1.7
Rb content in liver1.31.63.10.60.6-1.80.6-1.61.6-1.4
Se content in liver0.40.51.2-1.1-1.10.50.9-0.30.3-0.2
Sr content in liver0.30.30.50.30.30.4-0.70.7-0.70.7
Zn content in liver2.32.64.30.70.91.2-1.82.1-2.11.9
Bone: minimum diameter0.51.01.80.70.90.4-1.31.1-1.11.0
Time in familiar zone, hab. session 10.50.51.00.60.70.2-1.00.8-0.80.4
Time in novel zone, hab. session 10.40.40.8-0.8-0.90.20.9-0.50.5-0.5
Total zone transitions, hab. session 10.81.12.2-1.3-1.30.01.5-0.90.9-0.7
Total locomotion distance, hab. session 10.30.40.9-0.7-0.6-0.20.9-0.70.7-0.4
Locomotion velocity, hab. session 10.30.40.8-0.5-0.5-0.40.9-0.80.8-0.5
Time in familiar zone, hab. session 20.20.20.4-0.4-0.5-0.10.6-0.40.4-0.5
Time in novel zone, hab. session 20.00.00.1-0.1-0.00.3-0.10.3-0.30.2
Total zone transitions, hab. session 20.40.50.91.00.9-0.2-0.90.5-0.50.5
Total locomotion distance, hab. session 21.01.32.31.51.5-0.3-1.40.8-0.81.1
Locomotion velocity, hab. session 20.91.22.01.31.3-0.1-1.40.9-0.91.1
Novel to familiar place preference ratio0.80.81.91.41.4-0.6-1.10.4-0.40.3
Novelty place preference0.90.92.01.41.4-0.6-1.10.4-0.40.3
Time in novel zone, NPP test0.70.81.91.41.4-0.8-1.00.1-0.10.1
Total zone transitions, NPP test0.10.10.30.50.5-0.5-0.2-0.10.1-0.4
Total locomotion distance, NPP test0.20.30.70.50.4-0.80.2-0.70.7-0.5
Locomotion velocity, NPP test0.20.20.40.10.0-0.50.4-0.60.6-0.5
Intraocular pressure0.00.00.20.20.2-0.2-0.1-0.10.1-0.4
Delta distance traveled before/after self-admin1.61.83.00.60.4-1.70.8-1.71.7-1.5
Delta ambulatory time before/after self-admin0.91.01.90.30.1-1.20.7-1.31.4-1.0
Parametrial fat weight1.02.04.0-1.5-1.5-0.32.0-1.51.5-1.2
Pavlov. Cond. lever latency0.60.81.5-1.0-1.0-0.01.2-0.70.7-0.9
Pavlov. Cond. magazine entry latency8.310.716.71.61.72.4-3.84.1-4.13.9
Pavlov. Cond. change in total contacts3.13.35.61.31.30.9-2.22.1-2.12.4
Pavlov. Cond. index score3.24.16.50.80.91.6-2.32.6-2.52.5
Pavlov. Cond. latency score2.22.84.30.90.91.2-2.02.1-2.12.1
Pavlov. Cond. lever contacts1.11.32.30.90.90.6-1.51.3-1.31.3
Pavlov. Cond. magazine entry number6.58.113.4-0.9-1.0-2.43.1-3.63.6-3.7
Pavlov. Cond. intertrial magazine entries1.72.03.2-0.9-0.9-0.91.8-1.81.8-1.5
Pavlov. Cond. lever-magazine prob. diff.3.34.16.41.01.01.5-2.42.5-2.52.5
Pavlov. Cond. response bias5.66.910.51.31.41.9-3.13.2-3.23.2
Pavlov. Cond. lever latency0.70.91.70.0-0.1-1.10.9-1.31.3-1.0
Pavlov. Cond. magazine entry latency1.51.73.6-1.7-1.61.90.41.0-1.00.8
Pavlov. Cond. change in total contacts0.30.40.9-0.3-0.30.9-0.40.8-0.80.4
Pavlov. Cond. index score0.50.71.5-0.6-0.51.2-0.41.0-1.00.7
Pavlov. Cond. latency score0.30.40.9-0.5-0.41.0-0.20.8-0.80.4
Pavlov. Cond. lever contacts0.60.81.40.10.20.9-0.91.2-1.20.9
Pavlov. Cond. magazine entry number1.31.63.31.71.6-1.8-0.5-0.90.9-0.7
Pavlov. Cond. intertrial magazine entries0.50.71.10.40.1-1.00.6-1.01.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.70.91.9-0.6-0.61.4-0.41.2-1.20.8
Pavlov. Cond. response bias1.52.03.6-0.2-0.11.7-1.21.9-1.91.6
Time in closed arm before self-admin0.80.91.40.10.11.1-1.01.2-1.11.2
Time in closed arm after self-admin0.10.10.10.20.20.1-0.30.2-0.20.3
Time in open arm before self-admin1.01.12.61.01.0-1.60.1-1.11.1-0.8
Time in open arm after self-admin0.80.91.7-1.1-0.9-0.31.3-0.90.9-0.8
Bone: periosteal estimation0.71.42.81.41.5-1.7-0.4-0.80.8-1.1
Bone: periosteal perimeter0.91.42.81.51.6-1.7-0.5-0.70.7-1.0
Bone: post-yield work0.10.10.30.30.5-0.4-0.3-0.10.10.5
Progressive ratio test 1 active lever presses0.80.81.5-1.0-0.9-0.21.2-0.90.9-0.7
Progressive ratio test 1 breakpoint0.60.61.4-1.2-1.10.21.1-0.50.5-0.2
Progressive ratio test 1 inactive lever presses2.72.95.7-2.4-2.40.52.4-1.31.3-0.3
Progressive ratio test 2 active lever presses0.20.20.3-0.3-0.2-0.30.5-0.50.50.3
Progressive ratio test 2 breakpoint0.30.30.8-0.2-0.2-0.60.7-0.90.9-0.0
Progressive ratio test 2 inactive lever presses0.50.61.4-1.2-1.01.00.40.3-0.30.9
Incentive Sensitization - Responses0.70.71.71.01.1-0.5-0.90.1-0.11.3
Incentive Sensitization - Breakpoint0.70.71.90.91.0-0.3-0.90.3-0.21.4
Sum of active levers in priming session hrs 5-60.20.20.3-0.4-0.4-0.20.5-0.40.4-0.3
Progressive ratio2.22.54.80.60.81.3-1.92.2-2.21.4
Food seeking constrained by brief footshock1.72.03.80.2-0.1-1.61.3-1.81.8-2.0
Seeking ratio, punishment vs. effort4.55.510.30.50.2-2.92.0-3.23.2-2.4
Retroperitoneal fat weight0.10.30.50.1-0.1-0.60.5-0.70.7-0.6
Reaction time number correct0.81.22.41.31.3-1.6-0.2-1.01.1-0.4
Reaction time mean minus median1.01.32.2-1.5-1.50.41.4-0.70.6-1.3
Reaction time mean minus median AUC2.02.64.9-2.2-2.20.62.1-0.90.8-1.6
Reaction time num false alarms0.60.81.5-1.2-1.20.41.1-0.60.6-0.5
Reaction time num false alarms AUC1.11.52.5-1.2-1.1-0.31.6-1.31.3-1.3
Reaction time trials correct on left0.81.22.41.31.3-1.6-0.2-1.01.1-0.4
Reaction time trials on left0.91.22.61.31.2-1.6-0.2-1.11.1-0.5
Reaction time mean1.82.56.2-2.5-2.41.91.30.3-0.4-0.1
Reaction time mean AUC1.82.45.9-2.4-2.41.71.40.1-0.2-0.5
Median of all reaction times2.02.76.0-2.4-2.42.21.00.7-0.80.4
Reaction time omissions0.40.61.1-0.1-0.2-0.70.7-1.01.0-0.9
Reaction time false alarm rate1.01.43.1-1.8-1.70.71.5-0.50.5-0.8
Reaction time premature initiation rate0.40.51.31.10.9-1.2-0.2-0.40.4-0.1
Reaction time premature initiations0.91.33.01.61.4-1.7-0.3-0.80.8-0.2
Std. dev. reaction times1.41.94.5-2.1-2.11.11.6-0.30.3-0.9
Reaction time trials completed0.91.22.61.31.2-1.6-0.2-1.11.1-0.5
Reaction time trials AUC0.71.12.21.31.2-1.5-0.2-1.01.0-0.4
Run reversals in cocaine runway, females0.30.30.6-0.3-0.1-0.60.6-0.80.8-0.4
Run reversals in cocaine runway, males0.60.51.0-0.1-0.2-0.60.7-0.90.9-1.0
Latency to leave start box in cocaine runway1.21.32.41.21.3-1.6-0.3-0.70.7-1.4
Latency to leave start box in cocaine runway, F0.70.71.70.40.4-1.10.3-1.01.0-1.3
Latency to leave start box in cocaine runway, M1.41.33.21.71.8-1.3-1.0-0.10.0-0.7
Std. dev. time between licks in bursts1.82.23.81.91.7-0.2-1.81.1-1.11.6
Total sessions with >9 infusions1.51.73.2-1.6-1.60.01.8-1.21.2-0.8
Short access day 1 total inactive lever presses2.02.24.1-1.2-1.3-0.72.0-1.81.8-1.3
Short access day 10 total inactive lever presses0.91.01.9-1.3-1.30.21.4-0.90.9-0.2
Short access day 1 total infusions0.70.71.6-1.3-1.20.21.2-0.60.6-0.1
Short access day 10 total infusions1.21.43.1-1.8-1.70.61.5-0.60.7-0.5
Short access total infusions2.02.25.0-2.2-2.20.71.9-0.80.8-0.3
Short access day 1 locomotion0.10.10.3-0.4-0.4-0.10.5-0.30.3-0.1
Short access day 10 total locomotion0.60.71.2-0.5-0.5-0.61.1-1.11.1-0.8
Short access total locomotion1.01.02.4-1.5-1.50.61.3-0.40.4-0.4
One hour access (0.3 mA shock)0.00.00.1-0.2-0.1-0.00.1-0.10.0-0.3
Compulsive drug intake0.10.10.30.50.4-0.60.0-0.20.2-0.2
One hour access (shock baseline)0.20.20.7-0.8-0.70.50.4-0.00.00.0
Social response proportion1.21.42.21.01.10.2-1.51.2-1.31.3
Social responses0.10.10.20.30.4-0.2-0.40.2-0.20.3
Social time0.70.91.6-0.6-0.6-0.51.1-1.11.1-1.3
Soleus weight6.920.240.46.26.1-6.4-2.1-2.72.7-2.8
Bone: stiffness0.81.22.30.40.4-1.50.7-1.51.5-1.1
Tibialis anterior weight5.518.740.35.45.2-6.3-1.2-3.33.3-3.2
Time to tail flick, vehicle, before self-admin0.00.00.10.30.2-0.1-0.20.1-0.20.0
Time to tail flick, vehicle, after self-admin0.10.10.20.20.4-0.3-0.2-0.10.10.0
Time to tail flick, test, before self-admin2.22.24.10.30.51.5-1.62.0-2.01.4
Time to tail flick, test, after self-admin1.61.74.2-2.0-1.90.91.5-0.40.4-0.5
Delta time to tail flick, vehicle, before/after SA0.10.00.1-0.3-0.20.20.00.2-0.20.3
Delta time to tail flick, test, before/after SA2.62.34.1-1.5-1.4-0.62.0-1.71.7-1.5
Tibia length0.30.91.60.40.70.6-1.31.2-1.21.0
Ambulatory time before self-admin0.10.10.2-0.4-0.40.50.10.3-0.30.4
Ambulatory time after self-admin0.70.81.60.0-0.1-1.00.9-1.31.3-0.7
Bone: tissue strength0.80.71.4-1.1-1.11.20.40.6-0.60.7
Total heroin consumption0.91.02.50.90.7-1.60.3-1.21.2-0.7
Bone: trabecular number0.40.61.4-0.8-0.61.2-0.20.8-0.80.6
Bone: trabecular spacing0.10.10.2-0.4-0.4-0.00.4-0.30.3-0.3
Bone: trabecular thickness0.00.10.2-0.4-0.30.20.2-0.10.1-0.0
Bone: trabecular tissue density2.84.08.22.32.1-2.9-0.2-1.91.9-1.7
Water consumed over 24 hours0.20.20.4-0.7-0.60.60.30.2-0.2-0.2
Number of responses in last shaping day0.20.20.7-0.5-0.50.30.4-0.10.10.8