Hub : Genes

Fosl1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Fosl1 0.03 0.02 6.8e-03 0 0 0 0 1.7e-01 7.2e-02 3.4e-01 3.5e-01
2 BLA gene expression Fosl1 0.12 0.07 2.8e-05 0.05 0.07 0.07 0.07 7.5e-04 8.5e-05 2.0e-04 1.6e-04
3 IC gene expression Fosl1 0.24 0.13 4.3e-07 0.14 0.12 0.16 0.16 1.9e-06 1.2e-05 3.5e-07 2.5e-07
4 pVTA gene expression Fosl1 0.35 0.15 2.5e-09 0.1 0.12 0.13 0.12 1.1e-08 3.9e-10 1.1e-10 1.6e-09
5 NAcc gene expression Fosl1 0.13 0.07 1.1e-16 0.09 0.11 0.1 0.11 5.1e-14 1.2e-16 3.8e-15 9.3e-16
6 Adipose gene expression Fosl1 0.07 0.04 1.6e-06 0.04 0.04 0.04 0.04 4.2e-05 1.8e-05 7.6e-05 1.2e-05
7 Brain gene expression Fosl1 0.09 0.05 1.2e-05 0.06 0.04 0.05 0.05 3.5e-06 9.5e-05 2.5e-05 1.4e-05
8 PL gene expression Fosl1 0.21 0.09 0.0e+00 0.17 0.16 0.17 0.17 6.6e-18 1.4e-17 4.9e-18 4.4e-18
9 OFC gene expression Fosl1 0.27 0.15 3.5e-03 0.14 0.04 0.08 0.1 4.5e-04 3.2e-02 6.1e-03 2.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density2.44.57.40.8-2.3-2.51.6-2.3-2.02.7-2.41.8
Area under the delay curve0.71.01.4-0.3-0.9-1.21.0-1.0-0.81.1-1.21.2
BMI with tail6.020.926.22.5-5.0-4.94.3-4.8-5.14.7-4.74.7
BMI without tail1.79.211.91.4-3.1-3.23.2-2.9-3.23.4-3.23.2
Body weight2.310.213.33.7-3.3-3.03.5-2.9-3.23.0-3.03.1
Weight adjusted by age0.10.32.61.6-0.2-0.20.0-0.1-0.20.3-0.10.1
Bone surface3.67.09.83.1-2.8-3.01.7-2.9-2.33.0-2.62.1
Bone volume2.34.66.31.9-2.4-2.51.2-2.5-2.12.4-2.21.8
Breakpoint value in progressive ratio session0.91.75.52.4-1.3-1.01.0-1.1-1.21.0-1.01.0
Number of licking bursts0.00.10.70.8-0.4-0.20.1-0.4-0.2-0.0-0.20.2
Context. condit. distance diff. score0.40.53.0-1.70.50.7-0.20.40.1-0.20.3-0.1
Locomotion velocity, session 10.20.20.5-0.20.60.50.20.70.4-0.60.5-0.3
Locomotion distance, session 12.12.73.70.6-1.6-1.81.9-1.5-1.81.7-1.81.6
Locomotion velocity, session 22.22.63.71.9-1.6-1.61.9-1.4-1.61.3-1.51.6
Locomotion distance, session 21.82.54.00.8-1.5-1.92.0-1.4-1.61.6-1.61.6
Locomotion velocity, session 30.60.71.3-0.4-0.8-0.71.0-0.8-1.00.3-0.91.1
Locomotion distance, session 30.00.00.1-0.1-0.00.10.10.00.0-0.30.10.0
Stereotopy head waving bouts, day 30.60.71.2-1.1-0.6-0.70.9-0.6-0.90.8-0.91.0
Stereotopy head waving duration, day 30.30.31.4-1.2-0.3-0.40.2-0.5-0.40.5-0.60.5
Locomotion velocity, session 71.82.02.9-0.4-1.4-1.31.2-1.4-1.71.7-1.51.7
Locomotion distance, session 70.81.12.0-0.2-0.9-0.71.4-0.7-1.11.3-1.11.3
Stereotopy head waving bouts, day 70.30.40.90.1-0.8-0.8-0.1-1.0-0.60.4-0.60.5
Stereotopy head waving duration, day 71.11.32.31.1-1.4-1.40.5-1.5-1.10.9-1.21.0
Locomotion velocity, session 80.10.20.70.80.20.00.70.30.20.30.0-0.3
Locomotion distance, session 80.30.50.9-0.5-0.6-0.50.8-0.6-0.90.6-0.60.8
Degree of sensitization distance1.11.22.5-0.0-0.9-1.01.2-0.9-1.11.6-1.21.2
Degree of sensitization stereotypy0.50.61.11.0-1.0-0.8-0.0-1.1-0.70.3-0.60.6
Conditioned locomotion0.30.41.91.4-0.4-0.20.8-0.2-0.30.4-0.20.4
Cocaine response after cond. corrected0.30.52.2-1.50.70.7-0.00.80.4-0.60.4-0.2
Cocaine response after cond. not corrected0.20.31.5-1.20.60.5-0.10.60.4-0.60.3-0.1
Cocaine response before conditioning0.20.31.51.2-0.6-0.5-0.1-0.6-0.4-0.0-0.30.2
Saline control response1.21.74.82.2-1.0-1.21.6-0.8-0.71.4-1.20.8
Bone: connectivity density4.06.310.71.9-2.6-2.92.0-2.6-2.33.3-2.72.1
Bone: cortical apparent density0.10.21.00.40.30.4-0.00.40.3-1.00.6-0.3
Bone: cortical area0.10.22.01.4-0.30.00.0-0.2-0.20.00.10.1
Bone: cortical porosity0.50.61.00.3-0.8-1.00.7-0.8-0.70.5-0.90.7
Bone: cortical porosity0.70.81.30.6-0.9-1.10.9-0.9-0.90.7-1.00.9
Bone: cortical thickness0.61.05.82.40.40.70.50.80.5-0.70.7-0.5
Bone: cortical thickness0.30.40.90.60.60.70.50.90.6-0.70.5-0.4
Bone: cortical tissue density0.10.20.90.50.30.40.00.40.3-1.00.5-0.3
Condit. Reinf. active minus inactive responses0.50.50.70.5-0.8-0.80.8-0.6-0.70.6-0.80.8
Condit. Reinf. active-inactive response ratio0.10.10.10.2-0.3-0.30.3-0.2-0.20.2-0.30.3
Condit. Reinf. active responses0.40.60.90.4-0.9-0.80.7-0.7-0.90.6-0.70.9
Condit. Reinf. inactive responses0.30.40.80.0-0.7-0.50.4-0.6-0.90.4-0.60.8
Incentive salience index mean1.21.52.00.7-1.3-1.21.3-1.1-1.41.2-1.31.4
Condit. Reinf. lever presses0.71.01.61.1-1.1-0.70.8-1.0-1.31.0-0.81.2
Condit. Reinf. active minus inactive responses0.10.10.3-0.0-0.4-0.4-0.5-0.5-0.20.5-0.30.0
Condit. Reinf. active-inactive response ratio0.10.20.9-0.4-0.2-0.1-1.0-0.4-0.10.10.00.0
Condit. Reinf. active responses0.60.81.50.4-1.0-1.20.3-1.2-0.91.2-1.00.5
Condit. Reinf. inactive responses1.01.42.20.5-1.2-1.51.4-1.2-1.21.3-1.40.9
Condit. Reinf. lever presses1.11.64.22.0-1.4-1.30.4-1.4-1.01.4-1.00.7
Condit. Reinf. lever reinforcers received0.60.81.40.7-1.0-1.10.3-1.2-0.91.2-0.90.4
Conditioned reinforcement - actives0.20.83.30.30.60.6-1.80.50.8-0.70.8-1.0
Conditioned reinforcement - inactives0.92.47.4-1.71.21.2-2.71.01.4-1.11.3-1.5
Conditioned locomotion3.75.510.1-3.22.12.1-3.21.82.1-1.92.1-2.1
Patch foraging indifference point 0 sec0.00.10.2-0.2-0.3-0.20.2-0.4-0.40.1-0.30.3
Patch foraging indifference point AUC0.20.64.42.1-0.5-0.30.1-0.4-0.20.2-0.10.0
Delay disc. indifference point, 0s delay0.91.01.4-1.0-0.9-1.11.0-1.0-0.81.1-1.11.2
Delay disc. indifference point, 16s delay0.10.20.5-0.7-0.5-0.5-0.1-0.6-0.30.3-0.40.4
Delay disc. indifference point, 2s delay0.10.20.2-0.4-0.4-0.50.1-0.5-0.20.4-0.40.4
Delay disc. indifference point, 24s delay0.10.10.2-0.40.40.30.20.50.4-0.20.1-0.1
Delay disc. indifference point, 4s delay0.70.71.1-0.6-0.6-0.91.1-0.6-0.61.0-1.01.1
Delay disc. indifference point, 8s delay0.30.50.9-0.4-0.5-0.80.9-0.6-0.50.9-0.90.9
Indifference point function ln k1.03.214.7-3.81.71.6-0.81.71.1-1.31.2-0.8
Indifference point function log k1.03.214.7-3.81.71.6-0.81.71.1-1.31.2-0.8
Patch foraging total patch changes 0 sec0.00.00.1-0.10.20.20.20.20.0-0.30.1-0.1
Patch foraging total patch changes 12 sec2.12.87.12.7-1.7-1.51.7-1.5-1.61.4-1.41.3
Patch foraging total patch changes 18 sec0.30.71.11.0-1.0-1.00.6-1.0-0.80.7-0.80.8
Patch foraging total patch changes 24 sec0.10.32.91.7-0.1-0.00.3-0.0-0.00.1-0.0-0.2
Patch foraging total patch changes 6 sec0.71.11.71.3-1.0-1.01.3-0.8-0.91.0-1.00.9
Patch foraging time to switch 0 sec1.66.38.21.9-2.8-2.91.9-2.8-2.62.4-2.52.5
Patch foraging water rate 0 sec2.49.111.3-2.73.33.4-2.73.22.9-2.83.0-3.0
Patch foraging water rate 12 sec3.212.718.6-4.34.03.5-2.83.83.7-3.03.3-3.4
Patch foraging water rate 18 sec1.43.26.0-2.52.01.7-1.02.01.8-1.71.5-1.5
Patch foraging water rate 24 sec4.56.48.0-2.82.82.7-2.02.72.4-2.42.5-2.2
Patch foraging water rate 6 sec4.76.99.6-2.93.12.8-1.73.12.8-2.32.4-2.4
Seeking ratio, delayed vs. immediate footshock0.50.71.3-0.3-0.9-1.00.6-0.9-0.90.7-1.01.1
Distance traveled before self-admin0.51.01.61.0-1.2-1.20.4-1.3-1.00.9-0.90.9
Distance traveled after self-admin0.10.10.40.6-0.3-0.30.1-0.4-0.20.2-0.20.2
Extensor digitorum longus weight2.811.136.06.0-3.0-2.23.7-2.4-2.92.8-2.42.9
Bone: elastic displacement2.53.25.0-1.12.12.0-1.02.21.9-1.71.8-1.8
Bone: elastic work0.30.41.01.00.50.60.80.80.4-0.20.4-0.3
Bone: endosteal estimation0.71.72.9-1.2-1.2-1.30.4-1.4-1.31.7-1.41.4
Bone: endosteal perimeter0.71.73.2-1.2-1.2-1.3-0.2-1.5-1.21.8-1.31.2
Epididymis fat weight0.73.810.9-3.31.51.8-2.71.11.2-1.71.7-1.3
Delta time in closed arm before/after self-admin0.20.21.60.00.1-0.21.30.3-0.10.4-0.30.3
Delta time in open arm before/after self-admin0.20.20.90.8-0.10.1-1.0-0.20.1-0.30.3-0.3
Diff in mean of infusions in LGA sessions0.10.10.90.9-0.0-0.10.30.00.10.1-0.0-0.1
Delay discount exponential model param0.60.81.10.20.81.0-0.90.80.7-1.01.1-1.1
Extinction: sum of active levers before priming2.03.13.92.0-1.9-1.71.6-1.7-1.81.7-1.61.7
Active lever presses in extinction session 60.60.64.72.2-0.6-0.20.1-0.6-0.40.0-0.20.2
Bone: final force1.01.74.72.2-1.2-1.11.1-1.1-1.11.4-1.01.0
Bone: final moment1.01.54.22.0-1.2-1.11.1-1.0-1.11.3-1.01.0
Food consumed during 24 hour testing period0.51.01.50.30.91.1-1.20.81.1-1.11.1-1.2
Glucose0.91.44.6-2.1-0.8-1.20.5-1.0-1.00.7-1.11.3
Heart weight1.72.73.3-1.6-1.4-1.81.8-1.4-1.41.6-1.81.8
Delay discount hyperbolic model param0.60.81.10.30.81.0-0.80.90.7-1.01.1-1.1
Intermittent access intake day 1-15 change0.42.04.7-1.11.21.3-2.21.11.3-1.41.4-1.4
Intermittent access intake escalation0.42.15.2-0.91.31.4-2.31.11.3-1.41.5-1.5
Intermittent access intake escalation 21.11.94.4-0.91.21.4-2.11.01.2-1.51.5-1.4
Intermitt. access day 1 inactive lever presses0.00.10.3-0.30.30.4-0.60.30.3-0.30.4-0.3
Intermitt. access day 15 inactive lever presses0.10.62.9-1.20.30.3-1.70.20.5-0.20.5-0.7
Intermitt. access escalation Index0.20.65.3-2.30.40.2-0.40.20.2-0.10.2-0.2
Intermittent access day 1 total infusions0.51.53.2-1.8-1.2-1.4-0.4-1.4-0.91.4-1.20.8
Intermittent access day 15 total infusions0.81.97.1-2.40.70.6-2.70.41.0-0.60.8-1.1
Intermittent access terminal intake (last 3 days)0.71.25.3-2.10.20.1-2.3-0.10.5-0.20.4-0.7
Intermittent access total infusions0.60.83.4-1.9-0.4-0.6-1.4-0.6-0.10.6-0.4-0.1
Intermittent access day 1 locomotion0.40.82.4-1.6-0.7-0.9-0.4-0.9-0.61.1-0.80.5
Intermittent access day 15 total locomotion0.31.36.3-2.00.30.3-2.50.00.6-0.40.5-0.8
Intermittent access total locomotion1.11.36.2-2.5-0.2-0.2-2.3-0.60.00.2-0.0-0.3
Intermittent access standard deviation0.31.73.5-1.31.21.1-1.91.11.3-1.01.2-1.4
Left kidney weight0.00.43.0-1.70.10.2-0.6-0.1-0.30.00.30.1
Right kidney weight0.11.01.5-1.20.91.2-1.10.80.7-1.11.1-0.7
Cocaine induced anxiety0.00.00.20.3-0.20.1-0.5-0.2-0.1-0.10.10.0
Post-drug Anxiety0.20.21.21.1-0.4-0.20.1-0.4-0.30.1-0.10.3
Baseline Anxiety0.10.10.50.50.2-0.00.70.20.1-0.20.1-0.1
Tail length0.10.51.11.00.80.70.41.00.8-0.30.6-0.6
Length with tail0.21.17.92.8-0.10.11.30.20.10.10.00.1
Length without tail0.20.96.02.40.10.31.20.40.2-0.40.2-0.2
Times rat made contact with spout0.60.61.40.5-0.7-0.91.0-0.6-0.51.2-0.90.6
Lifetime Intake0.50.62.7-1.6-0.5-0.7-0.9-0.6-0.20.8-0.50.1
Liver weight, left0.50.92.0-1.41.10.9-0.51.10.8-0.90.8-0.7
Liver weight, right0.91.55.9-2.41.31.1-0.41.31.0-0.90.8-0.8
Locomotor activity2.13.34.8-2.12.11.8-1.12.21.9-1.51.6-1.7
Locomotor testing distance1.64.06.1-2.52.41.9-1.12.42.2-1.51.7-1.9
Locomotor testing rearing0.62.26.6-2.61.70.9-0.81.61.7-0.60.9-1.4
Locomotion in novel chamber1.82.47.1-2.71.31.2-2.01.01.2-1.31.3-1.3
Locomotion in novel chamber post-restriction0.41.33.9-2.00.80.8-1.70.60.9-1.00.9-0.8
Fecal boli incidents, locomotor time 10.10.21.20.5-0.00.2-1.1-0.20.2-0.40.3-0.1
Change in fecal boli incidents, locomotor task0.40.41.5-0.3-0.4-0.61.2-0.3-0.60.7-0.70.6
Time >=10cm from walls, locomotor time 10.70.92.0-0.5-1.2-1.1-0.4-1.4-1.00.9-0.90.9
Bouts of movement, locomotor time 10.20.32.41.5-0.2-0.20.0-0.30.0-0.1-0.10.4
Total resting periods, locomotor time 10.20.31.81.3-0.3-0.3-0.1-0.4-0.10.0-0.10.4
Rest time, locomotor task time 10.91.52.3-1.31.21.3-1.51.01.2-1.21.2-1.0
Distance moved, locomotor task time 10.51.41.80.3-1.3-1.31.2-1.2-1.31.3-1.31.0
Vertical activity count, locomotor time 10.00.21.2-1.10.30.3-0.30.40.2-0.20.1-0.2
Time >=10cm from walls, locomotor time 20.00.10.20.4-0.3-0.2-0.4-0.4-0.40.10.00.1
Bouts of movement, locomotor time 20.10.40.70.9-0.6-0.70.4-0.6-0.40.5-0.60.7
Total resting periods, locomotor time 20.10.40.60.6-0.7-0.70.4-0.7-0.50.6-0.60.7
Rest time, locomotor task time 20.40.73.0-1.70.70.7-0.90.50.7-0.60.5-0.2
Distance moved, locomotor task time 20.20.21.71.3-0.3-0.20.5-0.1-0.20.1-0.1-0.1
Vertical activity count, locomotor time 20.61.42.6-0.11.41.4-0.51.61.2-1.31.2-1.2
Light reinforcement 10.10.20.5-0.50.50.3-0.40.50.5-0.30.4-0.7
Light reinforcement 20.41.03.4-0.70.70.9-1.80.50.9-0.51.0-1.2
Bone: marrow area0.81.93.2-1.3-1.2-1.30.5-1.4-1.41.8-1.51.5
Bone: maximum diameter0.10.10.60.8-0.10.3-0.7-0.20.00.00.2-0.2
Bone: maximum force2.65.07.62.8-2.4-2.21.8-2.3-2.32.3-2.02.1
Bone: maximum moment2.44.66.82.6-2.3-2.11.7-2.2-2.22.1-2.02.0
Mean time between licks in bursts0.00.10.70.20.30.10.80.40.2-0.0-0.10.1
Mean num. licks in bursts0.10.20.6-0.80.1-0.30.30.1-0.10.7-0.2-0.1
Cd content in liver0.60.62.0-1.00.40.5-1.40.10.5-1.00.6-0.7
Co content in liver2.73.24.6-1.52.12.1-0.92.21.8-1.71.8-1.6
Cu content in liver0.40.50.90.1-0.8-0.60.5-0.7-1.00.5-0.70.8
Fe content in liver0.20.20.30.40.50.5-0.20.50.5-0.30.4-0.6
K content in liver1.11.11.80.6-1.1-0.81.4-0.9-1.21.0-1.11.2
Mg content in liver0.20.30.5-0.7-0.4-0.30.7-0.3-0.60.1-0.40.6
Mn content in liver0.80.95.52.3-0.9-0.40.5-0.8-0.70.3-0.40.3
Na content in liver0.50.60.90.80.71.0-0.40.70.6-0.90.9-0.7
Rb content in liver0.40.43.3-1.80.2-0.30.00.20.00.4-0.2-0.2
Se content in liver0.10.10.8-0.1-0.0-0.1-0.9-0.10.10.00.1-0.4
Sr content in liver0.60.52.71.60.20.8-0.10.20.3-0.80.6-0.5
Zn content in liver0.30.40.60.5-0.6-0.40.8-0.5-0.80.5-0.60.6
Bone: minimum diameter1.63.04.5-0.9-1.7-2.00.8-1.9-1.92.1-1.91.8
Time in familiar zone, hab. session 10.10.20.3-0.4-0.4-0.40.2-0.5-0.50.2-0.40.5
Time in novel zone, hab. session 10.80.91.4-0.71.21.1-0.41.21.1-0.70.8-0.9
Total zone transitions, hab. session 10.70.91.31.2-1.0-0.90.9-0.9-1.10.9-0.80.8
Total locomotion distance, hab. session 10.20.30.8-0.5-0.5-0.40.5-0.6-0.90.4-0.40.7
Locomotion velocity, hab. session 10.30.51.0-0.0-0.7-0.60.7-0.7-1.00.7-0.60.8
Time in familiar zone, hab. session 20.30.40.9-0.30.80.60.20.90.6-0.60.6-0.6
Time in novel zone, hab. session 20.70.71.20.3-1.0-1.00.4-1.1-0.81.0-0.90.9
Total zone transitions, hab. session 25.36.810.11.1-2.7-3.22.6-2.7-2.62.8-2.92.5
Total locomotion distance, hab. session 22.33.14.0-0.2-1.7-2.01.8-1.7-2.01.6-1.92.0
Locomotion velocity, hab. session 22.12.83.7-0.3-1.7-1.91.5-1.7-1.91.6-1.81.9
Novel to familiar place preference ratio0.60.82.01.4-1.1-0.80.1-1.2-0.70.6-0.60.6
Novelty place preference0.40.51.11.0-0.9-0.7-0.1-1.1-0.60.5-0.50.5
Time in novel zone, NPP test0.30.40.90.8-0.8-0.7-0.0-0.9-0.50.5-0.50.4
Total zone transitions, NPP test2.43.64.01.8-1.9-2.01.9-1.8-1.92.0-1.91.7
Total locomotion distance, NPP test1.11.62.30.2-1.2-1.31.4-1.1-1.51.5-1.31.4
Locomotion velocity, NPP test1.11.52.20.4-1.2-1.21.3-1.1-1.51.5-1.21.4
Intraocular pressure2.13.56.9-1.01.71.8-2.61.41.8-2.02.0-2.1
Delta distance traveled before/after self-admin0.50.51.0-0.50.90.9-0.01.00.8-0.60.7-0.7
Delta ambulatory time before/after self-admin0.20.40.8-0.30.80.80.10.90.7-0.50.6-0.6
Parametrial fat weight0.51.28.4-2.90.30.5-1.3-0.00.1-0.50.4-0.1
Pavlov. Cond. lever latency0.50.60.7-0.60.80.7-0.80.80.9-0.70.7-0.9
Pavlov. Cond. magazine entry latency1.41.82.40.7-1.5-1.41.1-1.6-1.61.3-1.31.5
Pavlov. Cond. change in total contacts0.60.61.20.7-1.0-0.70.1-1.1-1.00.4-0.60.9
Pavlov. Cond. index score0.20.30.50.7-0.6-0.40.3-0.6-0.60.3-0.30.6
Pavlov. Cond. latency score0.30.40.60.5-0.7-0.50.6-0.7-0.80.5-0.50.8
Pavlov. Cond. lever contacts0.50.60.80.4-0.8-0.70.8-0.7-0.90.7-0.70.9
Pavlov. Cond. magazine entry number0.10.10.8-0.90.40.20.10.40.30.1-0.0-0.2
Pavlov. Cond. intertrial magazine entries0.60.71.6-0.50.80.8-1.30.80.9-0.80.8-1.0
Pavlov. Cond. lever-magazine prob. diff.0.50.60.80.9-0.9-0.70.5-0.9-0.90.5-0.60.9
Pavlov. Cond. response bias0.10.10.60.8-0.4-0.10.0-0.4-0.4-0.1-0.10.3
Pavlov. Cond. lever latency0.10.21.4-1.20.30.10.30.30.1-0.20.00.0
Pavlov. Cond. magazine entry latency2.84.07.12.7-2.1-2.21.6-1.9-1.91.8-1.81.7
Pavlov. Cond. change in total contacts0.71.84.52.1-1.6-1.30.2-1.7-1.21.0-1.01.0
Pavlov. Cond. index score1.42.15.42.3-1.6-1.50.7-1.6-1.31.3-1.21.2
Pavlov. Cond. latency score1.11.84.82.2-1.5-1.30.6-1.4-1.31.2-1.11.1
Pavlov. Cond. lever contacts0.20.21.41.2-0.4-0.3-0.3-0.4-0.10.2-0.10.1
Pavlov. Cond. magazine entry number3.64.612.1-3.52.32.2-1.52.11.9-1.81.8-1.5
Pavlov. Cond. intertrial magazine entries0.40.81.7-1.30.81.0-1.00.70.9-0.80.7-0.7
Pavlov. Cond. lever-magazine prob. diff.1.62.56.32.5-1.7-1.60.8-1.7-1.41.4-1.31.2
Pavlov. Cond. response bias1.11.54.22.0-1.3-1.30.6-1.3-1.01.0-1.00.8
Time in closed arm before self-admin0.10.10.4-0.4-0.3-0.2-0.6-0.5-0.30.0-0.20.2
Time in closed arm after self-admin0.00.00.3-0.50.00.10.30.1-0.10.0-0.10.1
Time in open arm before self-admin0.30.41.3-0.90.60.31.20.90.3-0.10.1-0.0
Time in open arm after self-admin0.00.00.10.10.30.10.20.30.3-0.20.2-0.2
Bone: periosteal estimation0.20.61.10.2-0.9-0.70.1-0.9-0.91.0-0.70.9
Bone: periosteal perimeter0.40.81.40.6-1.0-0.70.3-1.1-0.91.2-0.90.9
Bone: post-yield work7.913.719.31.3-4.3-4.12.4-4.4-4.33.5-3.84.0
Progressive ratio test 1 active lever presses0.10.10.6-0.4-0.1-0.2-0.8-0.10.20.3-0.1-0.3
Progressive ratio test 1 breakpoint0.10.10.7-0.3-0.1-0.2-0.8-0.10.20.3-0.1-0.3
Progressive ratio test 1 inactive lever presses0.00.10.5-0.20.10.0-0.70.00.20.20.1-0.3
Progressive ratio test 2 active lever presses0.60.84.1-1.40.40.2-2.00.20.7-0.20.4-0.8
Progressive ratio test 2 breakpoint0.70.94.3-1.40.50.3-2.10.30.7-0.30.5-0.9
Progressive ratio test 2 inactive lever presses0.92.79.3-3.10.90.8-3.00.61.1-0.71.0-1.3
Incentive Sensitization - Responses0.20.40.80.1-0.8-0.8-0.2-0.8-0.60.9-0.70.5
Incentive Sensitization - Breakpoint0.10.30.6-0.1-0.6-0.7-0.3-0.7-0.50.8-0.50.4
Sum of active levers in priming session hrs 5-63.23.05.11.71.31.8-2.31.31.6-1.91.9-1.8
Progressive ratio1.95.67.41.1-2.7-2.71.9-2.7-2.42.3-2.62.4
Food seeking constrained by brief footshock0.00.10.20.3-0.0-0.20.40.10.00.3-0.30.2
Seeking ratio, punishment vs. effort1.63.65.7-1.52.32.1-1.12.42.0-1.61.9-1.8
Retroperitoneal fat weight2.410.748.0-6.92.82.5-3.32.32.2-1.82.2-2.2
Reaction time number correct0.20.61.30.60.70.8-0.30.80.8-1.10.8-0.7
Reaction time mean minus median0.31.86.92.6-1.4-1.10.5-1.4-1.20.4-1.01.2
Reaction time mean minus median AUC0.10.53.61.9-0.5-0.2-0.0-0.4-0.3-0.5-0.00.3
Reaction time num false alarms0.30.51.2-0.80.81.00.51.10.4-0.20.5-0.2
Reaction time num false alarms AUC0.10.20.8-0.10.40.70.90.70.10.00.20.1
Reaction time trials correct on left0.20.61.30.60.70.8-0.30.80.8-1.10.8-0.7
Reaction time trials on left0.20.71.40.70.80.9-0.30.80.8-1.20.9-0.7
Reaction time mean0.10.10.30.5-0.4-0.2-0.4-0.5-0.1-0.6-0.00.2
Reaction time mean AUC0.10.20.40.4-0.5-0.3-0.4-0.6-0.3-0.5-0.10.4
Median of all reaction times0.10.10.2-0.2-0.2-0.2-0.5-0.4-0.0-0.50.00.1
Reaction time omissions0.50.83.71.9-0.9-0.60.6-0.7-0.70.2-0.60.8
Reaction time false alarm rate0.10.20.5-0.70.30.40.70.5-0.10.4-0.10.2
Reaction time premature initiation rate0.50.73.01.5-0.3-0.41.7-0.0-0.30.4-0.60.5
Reaction time premature initiations0.20.84.32.10.20.11.40.50.2-0.3-0.10.0
Std. dev. reaction times0.10.52.21.5-0.8-0.5-0.0-0.8-0.5-0.2-0.40.5
Reaction time trials completed0.20.71.40.70.80.9-0.30.80.8-1.20.9-0.7
Reaction time trials AUC0.20.61.30.50.80.9-0.20.80.8-1.10.8-0.6
Run reversals in cocaine runway, females2.12.35.10.4-1.5-1.42.3-1.3-1.71.3-1.51.7
Run reversals in cocaine runway, males2.83.14.0-0.51.92.0-1.52.01.8-1.91.9-1.7
Latency to leave start box in cocaine runway0.71.01.6-0.1-1.2-1.10.7-1.2-1.30.9-1.01.0
Latency to leave start box in cocaine runway, F0.60.71.0-0.1-1.0-1.00.6-1.0-1.00.7-0.90.9
Latency to leave start box in cocaine runway, M0.20.20.30.3-0.5-0.40.4-0.5-0.60.4-0.40.4
Std. dev. time between licks in bursts0.30.51.2-0.50.90.80.41.10.5-0.70.6-0.4
Total sessions with >9 infusions1.01.22.50.0-1.2-1.30.5-1.2-1.01.6-1.31.0
Short access day 1 total inactive lever presses0.20.53.1-1.80.50.3-0.60.40.4-0.20.3-0.4
Short access day 10 total inactive lever presses0.00.20.6-0.80.40.4-0.10.50.3-0.20.3-0.3
Short access day 1 total infusions0.30.62.0-1.4-0.6-0.6-0.1-0.7-0.50.9-0.70.5
Short access day 10 total infusions1.93.25.5-0.5-2.0-2.20.6-2.1-1.72.3-2.01.6
Short access total infusions0.91.32.6-0.6-1.2-1.40.4-1.2-1.01.6-1.31.0
Short access day 1 locomotion0.20.31.7-1.3-0.3-0.4-0.6-0.3-0.10.6-0.40.1
Short access day 10 total locomotion0.10.50.9-0.9-0.7-0.7-0.5-0.8-0.50.9-0.60.4
Short access total locomotion0.30.41.3-1.2-0.5-0.6-0.6-0.6-0.40.8-0.50.3
One hour access (0.3 mA shock)2.02.48.3-2.91.20.9-2.20.91.3-0.91.0-1.3
Compulsive drug intake0.40.52.61.10.50.31.60.70.3-0.10.1-0.0
One hour access (shock baseline)1.02.58.6-2.80.90.9-2.90.51.1-0.91.0-1.2
Social response proportion0.20.30.91.0-0.6-0.50.1-0.6-0.40.1-0.40.2
Social responses0.10.10.20.40.20.2-0.10.30.4-0.50.2-0.4
Social time0.10.10.20.50.40.4-0.00.40.5-0.30.3-0.4
Soleus weight1.54.314.3-3.82.01.9-2.01.81.5-1.41.7-1.5
Bone: stiffness2.34.25.22.3-2.3-2.11.4-2.3-2.02.1-1.91.8
Tibialis anterior weight1.75.742.16.5-1.3-0.52.0-0.8-1.00.8-0.60.9
Time to tail flick, vehicle, before self-admin0.50.60.90.4-0.9-0.90.5-0.9-0.80.9-0.80.8
Time to tail flick, vehicle, after self-admin1.83.64.70.5-1.9-2.02.2-1.8-2.01.8-2.02.1
Time to tail flick, test, before self-admin0.91.02.6-1.6-0.7-1.10.7-0.7-0.91.0-1.10.9
Time to tail flick, test, after self-admin0.10.10.40.30.20.3-0.60.10.3-0.30.4-0.4
Delta time to tail flick, vehicle, before/after SA1.01.01.90.4-1.0-1.11.4-0.9-1.00.8-1.11.1
Delta time to tail flick, test, before/after SA2.42.93.61.61.51.9-1.71.51.7-1.81.9-1.8
Tibia length0.31.05.32.3-0.10.1-1.2-0.10.3-0.90.8-0.7
Ambulatory time before self-admin0.30.91.71.0-1.2-1.20.1-1.3-1.00.8-0.80.8
Ambulatory time after self-admin0.10.20.5-0.2-0.5-0.4-0.2-0.7-0.40.3-0.40.4
Bone: tissue strength0.10.10.20.1-0.4-0.40.1-0.4-0.40.4-0.30.2
Total heroin consumption1.72.07.42.7-1.3-1.21.4-1.2-1.10.9-1.01.1
Bone: trabecular number2.03.75.81.2-2.2-2.31.1-2.2-1.92.4-2.11.5
Bone: trabecular spacing0.40.51.0-1.00.90.7-0.00.90.6-1.00.6-0.3
Bone: trabecular thickness0.40.60.9-0.5-0.9-0.80.3-0.9-0.80.8-1.00.7
Bone: trabecular tissue density2.13.75.8-2.41.92.0-2.21.81.7-1.72.0-1.7
Water consumed over 24 hours0.10.21.11.0-0.3-0.50.5-0.20.00.4-0.3-0.1
Number of responses in last shaping day0.10.10.2-0.30.50.4-0.00.50.5-0.10.3-0.4