Hub : Genes

Tmem132a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Tmem132a 0.15 0.06 7.1e-12 0.13 0.12 0.12 0.12 4.9e-12 2.0e-11 1.3e-11 1.8e-11
2 PL mRNA stability Tmem132a 0.03 0.02 2.4e-03 0.03 0.02 0.02 0.02 8.2e-04 3.5e-03 3.4e-03 5.9e-03
3 pVTA gene expression Tmem132a 0.06 0.04 9.9e-04 0.05 0.03 0.04 0.04 1.2e-04 2.0e-03 3.8e-04 6.4e-04
4 OFC gene expression Tmem132a 0.29 0.14 2.5e-04 0.17 0.12 0.13 0.14 6.7e-05 7.7e-04 5.8e-04 3.9e-04
5 Liver intron excision ratio chr1_216937818_216938131 0.09 0.06 7.4e-04 0.03 0.03 0.01 0.02 5.5e-04 5.5e-04 6.7e-03 1.1e-03
6 Liver intron excision ratio chr1_216937815_216938131 0.09 0.06 6.7e-04 0.03 0.03 0.02 0.02 5.4e-04 4.4e-04 6.5e-03 1.0e-03
7 Liver isoform ratio NM_001415950.1 0.05 0.03 1.3e-03 0.01 0.02 0.01 0.01 2.2e-02 2.1e-03 3.2e-02 7.9e-03
8 Liver isoform ratio NM_178021.2 0.06 0.04 8.5e-04 0.01 0.02 0.01 0.02 1.5e-02 8.6e-04 1.9e-02 3.5e-03
9 BLA gene expression Tmem132a 0.08 0.05 3.7e-04 0.04 0.05 0.03 0.04 3.7e-03 1.3e-03 8.7e-03 2.2e-03
10 NAcc mRNA stability Tmem132a 0.07 0.04 1.0e-07 0.05 0.04 0.04 0.05 8.1e-08 2.6e-07 2.6e-07 1.8e-08
11 Adipose gene expression Tmem132a 0.11 0.05 3.3e-10 0.05 0.07 0.07 0.07 2.6e-06 4.8e-08 3.7e-08 1.7e-08
12 IC gene expression Tmem132a 0.2 0.09 6.2e-07 0.08 0.12 0.1 0.09 2.5e-04 8.9e-06 8.2e-05 1.1e-04
13 Brain gene expression Tmem132a 0.6 0.1 0.0e+00 0.5 0.57 0.57 0.58 1.4e-52 6.8e-65 4.5e-65 2.5e-65
14 BLA mRNA stability Tmem132a 0.13 0.07 1.9e-05 0.06 0.09 0.07 0.09 3.4e-04 2.7e-05 1.8e-04 1.4e-05
15 NAcc gene expression Tmem132a 0.12 0.06 0.0e+00 0.13 0.13 0.12 0.12 7.3e-19 1.3e-18 1.9e-18 1.8e-18
16 PL gene expression Tmem132a 0.05 0.03 1.2e-03 0 0.02 0.01 0 1.3e-01 5.5e-03 7.2e-02 8.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bone: apparent density0.30.61.20.70.70.60.31.1-1.11.0-1.00.90.80.70.70.80.10.50.4
Area under the delay curve0.80.93.01.41.01.7-0.3-0.00.00.1-0.10.41.30.90.70.81.31.01.3
BMI with tail3.210.919.20.70.6-0.03.53.2-3.23.7-3.74.32.24.44.14.23.54.32.6
BMI without tail0.72.04.20.20.4-0.21.40.8-0.91.3-1.31.81.12.11.91.92.01.81.5
Body weight2.712.022.00.30.2-0.13.53.2-3.23.9-3.94.72.14.64.44.44.14.12.8
Weight adjusted by age1.01.65.0-1.7-1.7-0.92.20.6-0.61.0-1.01.0-0.81.61.60.81.50.71.0
Bone surface0.81.53.70.70.60.81.00.6-0.60.9-0.91.41.31.51.61.61.91.11.7
Bone volume0.50.91.70.90.80.50.50.7-0.70.9-0.91.21.31.01.11.30.90.71.0
Breakpoint value in progressive ratio session1.11.34.7-2.1-2.2-1.91.70.3-0.30.5-0.50.5-1.50.90.60.10.2-0.1-0.4
Number of licking bursts0.20.20.60.70.6-0.00.00.2-0.20.3-0.30.80.60.60.50.80.50.50.4
Context. condit. distance diff. score0.30.30.60.20.40.60.20.7-0.70.8-0.80.60.40.50.70.50.70.20.6
Locomotion velocity, session 10.30.31.6-0.9-1.3-0.50.6-0.30.3-0.20.2-0.5-0.8-0.3-0.3-0.6-0.5-0.1-0.6
Locomotion distance, session 10.81.02.5-0.7-1.2-0.51.51.6-1.61.5-1.50.8-0.70.70.60.3-0.60.4-0.6
Locomotion velocity, session 21.41.73.6-0.5-0.50.11.91.8-1.81.8-1.81.5-0.01.41.51.20.51.10.6
Locomotion distance, session 20.81.12.5-0.8-1.1-0.71.41.6-1.61.6-1.50.9-0.70.60.60.3-0.70.4-0.8
Locomotion velocity, session 33.13.56.31.31.31.60.62.2-2.22.3-2.32.21.72.01.92.11.42.51.3
Locomotion distance, session 30.20.20.70.70.70.9-0.70.0-0.10.1-0.10.00.5-0.1-0.00.00.40.40.2
Stereotopy head waving bouts, day 31.01.24.61.20.91.20.21.1-1.11.0-1.01.01.31.20.81.10.42.20.7
Stereotopy head waving duration, day 30.91.03.00.80.80.90.50.6-0.60.7-0.71.01.31.41.01.30.81.71.1
Locomotion velocity, session 70.70.72.01.20.91.4-0.20.6-0.60.6-0.60.71.10.10.70.71.11.01.0
Locomotion distance, session 70.40.51.61.00.81.3-0.20.2-0.20.4-0.40.51.00.30.60.80.91.00.9
Stereotopy head waving bouts, day 70.20.21.1-0.1-0.20.20.5-0.30.3-0.10.10.10.10.60.50.11.10.60.7
Stereotopy head waving duration, day 70.30.41.5-0.2-0.3-0.11.00.1-0.10.3-0.30.60.11.00.90.61.20.70.9
Locomotion velocity, session 80.30.41.1-0.1-0.2-0.4-0.3-1.11.0-0.80.8-0.6-0.2-0.4-0.3-0.50.4-0.80.2
Locomotion distance, session 80.40.61.50.40.30.80.31.2-1.21.2-1.20.90.40.50.70.60.50.60.3
Degree of sensitization distance1.31.32.90.70.30.61.11.1-1.11.2-1.21.31.01.31.41.50.91.71.2
Degree of sensitization stereotypy0.40.52.2-0.6-0.7-0.21.1-0.10.10.2-0.20.5-0.20.91.00.41.50.40.9
Conditioned locomotion0.40.41.00.1-0.10.90.60.2-0.30.5-0.50.5-0.00.91.00.61.00.71.0
Cocaine response after cond. corrected0.10.10.2-0.4-0.50.00.40.2-0.20.3-0.30.1-0.20.30.40.10.30.20.3
Cocaine response after cond. not corrected0.10.10.5-0.6-0.70.10.50.4-0.50.4-0.4-0.1-0.5-0.10.1-0.3-0.1-0.1-0.1
Cocaine response before conditioning0.40.51.1-0.7-0.8-0.40.30.4-0.40.1-0.1-0.4-0.8-1.0-0.6-1.0-0.9-0.9-1.0
Saline control response0.50.62.3-1.0-1.4-1.11.50.3-0.30.4-0.40.5-1.00.80.70.30.60.20.1
Bone: connectivity density0.71.12.00.10.20.71.21.0-1.01.1-1.11.20.61.41.41.21.01.01.2
Bone: cortical apparent density0.30.41.0-0.7-0.7-0.40.50.8-0.80.7-0.70.1-0.8-0.2-0.1-0.4-0.7-0.4-1.0
Bone: cortical area0.40.62.50.1-0.0-0.20.31.6-1.61.3-1.30.80.1-0.00.10.3-0.3-0.1-0.9
Bone: cortical porosity0.50.51.4-0.7-0.7-0.60.1-1.21.2-1.01.0-0.7-0.5-0.1-0.3-0.50.3-1.00.1
Bone: cortical porosity0.50.51.4-0.8-0.8-0.60.4-1.21.2-0.90.9-0.6-0.50.1-0.1-0.40.5-0.80.2
Bone: cortical thickness1.22.04.5-2.0-2.1-1.91.41.4-1.41.2-1.10.3-1.8-0.1-0.3-0.7-1.2-1.0-2.0
Bone: cortical thickness0.30.30.9-0.7-0.50.10.10.6-0.60.5-0.4-0.2-0.6-0.3-0.4-0.6-0.8-0.9-1.0
Bone: cortical tissue density0.30.40.8-0.8-0.8-0.50.70.7-0.70.7-0.70.2-0.9-0.00.0-0.4-0.6-0.4-0.9
Condit. Reinf. active minus inactive responses1.01.13.0-1.4-1.7-1.31.61.0-1.01.0-1.00.5-1.30.70.2-0.1-0.8-0.1-1.2
Condit. Reinf. active-inactive response ratio1.41.55.3-1.9-2.3-1.81.40.2-0.20.2-0.2-0.4-1.90.1-0.4-0.9-1.2-0.9-1.6
Condit. Reinf. active responses1.41.84.4-1.0-1.2-0.71.72.1-2.11.9-1.91.2-0.81.00.60.4-1.00.6-1.1
Condit. Reinf. inactive responses1.11.34.10.40.70.70.32.0-2.01.8-1.81.40.60.60.71.0-0.41.2-0.1
Incentive salience index mean0.91.23.2-0.7-0.9-0.41.31.8-1.81.6-1.60.9-0.60.70.50.3-0.80.6-1.0
Condit. Reinf. lever presses0.60.82.60.40.40.80.41.6-1.61.3-1.41.00.50.60.60.7-0.21.00.0
Condit. Reinf. active minus inactive responses0.30.41.1-0.6-0.9-0.40.20.6-0.60.5-0.4-0.2-1.0-0.4-0.3-0.6-0.8-0.7-1.0
Condit. Reinf. active-inactive response ratio0.60.72.40.30.50.60.50.5-0.60.8-0.81.10.50.91.21.01.50.21.1
Condit. Reinf. active responses0.30.41.5-0.4-1.0-0.70.40.6-0.60.4-0.4-0.2-0.9-0.4-0.4-0.6-1.0-0.4-1.2
Condit. Reinf. inactive responses1.11.55.2-0.4-1.0-1.0-0.5-0.20.2-0.70.7-1.3-1.1-1.4-1.6-1.6-2.3-0.8-2.0
Condit. Reinf. lever presses0.60.81.50.1-0.2-0.61.21.2-1.11.1-1.11.20.21.01.01.10.30.70.2
Condit. Reinf. lever reinforcers received0.40.51.5-0.8-1.2-1.00.80.6-0.60.5-0.5-0.0-1.1-0.1-0.2-0.4-0.8-0.6-1.2
Conditioned reinforcement - actives0.30.51.0-0.9-0.9-0.3-0.1-0.70.7-0.70.7-0.9-1.0-0.8-0.4-0.8-0.2-0.8-0.1
Conditioned reinforcement - inactives0.40.61.40.50.60.60.41.2-1.21.1-1.11.00.60.50.70.90.30.80.2
Conditioned locomotion0.70.93.71.91.91.8-1.20.3-0.3-0.0-0.0-0.11.4-0.4-0.40.2-0.60.50.3
Patch foraging indifference point 0 sec0.10.20.6-0.0-0.2-0.60.60.8-0.80.6-0.60.5-0.10.50.30.4-0.10.4-0.1
Patch foraging indifference point AUC0.81.12.5-1.0-1.2-1.41.01.6-1.51.2-1.20.6-0.9-0.1-0.1-0.1-1.4-0.1-1.5
Delay disc. indifference point, 0s delay1.31.43.91.71.31.9-0.30.1-0.10.4-0.50.91.50.71.21.12.01.21.6
Delay disc. indifference point, 16s delay0.20.20.80.40.10.90.20.3-0.30.3-0.30.40.40.60.40.40.50.60.5
Delay disc. indifference point, 2s delay0.91.13.51.91.71.6-0.8-0.40.4-0.30.20.21.50.30.40.61.30.91.3
Delay disc. indifference point, 24s delay0.20.21.00.70.31.0-0.20.3-0.30.2-0.20.10.60.50.10.3-0.10.40.3
Delay disc. indifference point, 4s delay1.31.42.81.71.61.6-0.20.3-0.30.5-0.50.91.61.11.01.31.41.51.5
Delay disc. indifference point, 8s delay0.91.13.41.51.21.8-0.9-1.01.0-0.90.8-0.31.20.40.20.31.40.41.4
Indifference point function ln k0.61.13.11.61.81.4-1.4-0.90.9-0.80.8-0.31.4-0.4-0.10.21.10.31.2
Indifference point function log k0.61.13.11.61.81.4-1.4-0.90.9-0.80.8-0.31.4-0.4-0.10.21.10.31.2
Patch foraging total patch changes 0 sec0.10.20.7-0.4-0.5-0.70.60.8-0.80.6-0.60.3-0.40.2-0.00.1-0.50.1-0.5
Patch foraging total patch changes 12 sec1.82.46.3-2.0-2.0-1.22.52.0-1.91.9-1.81.4-1.31.51.10.8-0.20.3-0.7
Patch foraging total patch changes 18 sec0.50.72.1-1.0-1.5-1.40.60.8-0.80.5-0.50.1-1.1-0.2-0.3-0.3-0.9-0.5-1.2
Patch foraging total patch changes 24 sec2.64.410.4-0.5-0.7-1.12.33.2-3.23.1-3.02.70.32.41.92.00.61.7-0.0
Patch foraging total patch changes 6 sec0.40.71.80.20.1-0.40.71.3-1.31.2-1.11.10.30.80.70.80.20.90.1
Patch foraging time to switch 0 sec0.61.24.20.50.51.30.6-0.40.30.0-0.00.80.91.31.41.22.11.12.0
Patch foraging water rate 0 sec0.71.45.6-0.40.1-0.7-0.90.5-0.5-0.00.0-1.0-0.8-1.5-1.7-1.4-2.4-1.1-2.2
Patch foraging water rate 12 sec0.30.72.00.50.9-0.3-1.3-0.20.2-0.60.6-0.90.1-1.0-1.3-0.7-1.4-0.9-1.0
Patch foraging water rate 18 sec0.20.31.20.81.10.1-1.00.5-0.40.1-0.1-0.10.7-0.5-0.7-0.1-0.8-0.0-0.6
Patch foraging water rate 24 sec0.40.51.40.10.8-0.2-1.2-0.70.7-0.80.8-0.90.1-0.9-0.9-0.7-0.3-0.9-0.3
Patch foraging water rate 6 sec0.40.61.90.40.7-0.4-1.3-0.20.3-0.60.6-0.9-0.1-1.0-1.4-0.7-1.1-0.7-1.1
Seeking ratio, delayed vs. immediate footshock1.11.33.51.01.20.50.21.9-1.91.6-1.61.31.00.90.61.1-0.70.9-0.2
Distance traveled before self-admin0.81.12.3-0.6-0.3-0.41.41.0-1.01.1-1.11.40.01.51.41.21.10.80.7
Distance traveled after self-admin0.20.30.8-0.9-0.6-0.60.80.6-0.60.6-0.50.4-0.70.40.30.2-0.2-0.1-0.4
Extensor digitorum longus weight2.811.224.2-1.5-1.5-1.14.93.6-3.64.2-4.24.30.24.44.33.62.82.71.8
Bone: elastic displacement1.11.32.3-1.1-0.9-0.7-0.4-1.00.9-0.90.9-1.3-1.5-1.2-1.3-1.5-1.1-1.4-1.4
Bone: elastic work0.50.72.2-1.3-1.3-1.40.70.5-0.50.5-0.40.1-1.5-0.0-0.2-0.4-0.5-0.9-1.1
Bone: endosteal estimation1.43.09.23.03.02.4-1.40.5-0.50.5-0.51.12.90.50.71.71.51.31.7
Bone: endosteal perimeter1.73.611.63.43.42.7-1.8-0.10.00.1-0.10.93.20.30.71.71.91.42.0
Epididymis fat weight0.72.58.12.92.81.6-1.21.3-1.41.1-1.11.22.70.30.51.30.81.60.7
Delta time in closed arm before/after self-admin1.81.73.8-0.5-0.6-1.11.31.9-1.92.0-1.91.6-0.01.71.11.20.20.8-0.3
Delta time in open arm before/after self-admin1.01.02.6-1.3-1.3-0.01.61.3-1.31.4-1.40.9-0.70.90.90.50.20.4-0.1
Diff in mean of infusions in LGA sessions1.01.22.7-1.2-1.6-1.61.61.0-1.01.2-1.21.1-0.71.11.00.70.50.5-0.2
Delay discount exponential model param0.80.93.2-1.4-1.1-1.80.30.1-0.0-0.10.1-0.4-1.3-0.9-0.7-0.8-1.2-1.0-1.3
Extinction: sum of active levers before priming1.61.74.0-0.5-0.5-0.31.91.3-1.31.6-1.61.60.22.01.51.41.21.40.7
Active lever presses in extinction session 60.70.72.9-1.2-1.1-1.01.70.4-0.40.6-0.60.7-0.71.00.80.40.60.30.1
Bone: final force0.50.92.4-0.1-0.2-0.01.01.5-1.51.5-1.51.20.20.70.80.80.50.5-0.2
Bone: final moment0.50.82.4-0.2-0.3-0.11.01.5-1.51.5-1.41.20.10.70.70.70.40.5-0.3
Food consumed during 24 hour testing period0.40.61.1-0.8-0.3-0.3-0.6-0.60.6-0.80.8-1.0-0.6-1.1-1.0-1.0-0.8-0.9-0.8
Glucose0.71.15.12.31.71.2-1.6-0.70.7-0.70.7-0.31.4-0.4-0.50.20.21.20.4
Heart weight1.62.57.12.42.21.5-0.50.3-0.30.5-0.61.22.71.11.41.82.01.82.2
Delay discount hyperbolic model param0.91.03.4-1.5-1.3-1.80.40.2-0.20.0-0.0-0.4-1.4-0.8-0.7-0.8-1.4-1.1-1.4
Intermittent access intake day 1-15 change0.51.02.60.20.30.2-1.2-0.30.3-0.70.7-1.2-0.4-1.6-1.4-1.3-1.6-1.1-1.2
Intermittent access intake escalation0.51.12.90.10.10.2-1.1-0.30.3-0.70.7-1.2-0.5-1.7-1.5-1.4-1.7-1.1-1.3
Intermittent access intake escalation 20.30.31.5-0.10.0-0.4-0.50.4-0.40.0-0.0-0.4-0.3-0.8-0.7-0.6-1.2-0.6-0.9
Intermitt. access day 1 inactive lever presses0.00.10.3-0.2-0.10.1-0.10.1-0.10.1-0.1-0.1-0.3-0.4-0.2-0.3-0.1-0.5-0.3
Intermitt. access day 15 inactive lever presses1.73.57.90.91.20.81.32.8-2.82.7-2.62.61.31.51.72.00.41.80.6
Intermitt. access escalation Index0.50.73.41.21.01.8-1.10.4-0.40.1-0.1-0.50.8-0.7-0.6-0.4-1.1-0.2-0.2
Intermittent access day 1 total infusions2.64.17.72.72.82.70.31.6-1.71.7-1.71.92.71.41.72.11.32.52.0
Intermittent access day 15 total infusions1.01.56.02.42.42.3-1.30.6-0.60.2-0.2-0.11.6-0.8-0.40.1-0.90.60.2
Intermittent access terminal intake (last 3 days)1.31.74.32.02.12.0-0.21.4-1.51.2-1.21.11.70.30.61.0-0.11.30.7
Intermittent access total infusions2.02.46.82.42.52.6-0.31.3-1.31.1-1.21.12.10.50.81.30.41.71.2
Intermittent access day 1 locomotion2.02.54.21.71.72.10.61.6-1.61.6-1.61.61.91.31.41.70.82.01.4
Intermittent access day 15 total locomotion1.12.03.31.31.51.20.71.6-1.61.6-1.61.81.51.31.31.70.71.80.9
Intermittent access total locomotion3.84.67.32.42.62.50.62.4-2.52.3-2.32.32.51.51.72.20.72.71.4
Intermittent access standard deviation0.10.20.4-0.4-0.3-0.6-0.2-0.20.2-0.30.3-0.5-0.5-0.6-0.5-0.6-0.6-0.5-0.5
Left kidney weight0.73.19.12.92.82.1-0.90.4-0.50.6-0.61.33.00.81.11.72.12.02.0
Right kidney weight0.31.53.71.91.81.7-0.60.9-1.00.9-0.91.01.90.50.71.10.91.40.9
Cocaine induced anxiety0.30.51.3-1.1-1.1-1.10.4-0.70.7-0.50.5-0.5-1.0-0.4-0.2-0.60.0-0.7-0.3
Post-drug Anxiety0.20.20.8-0.5-0.6-0.80.6-0.50.5-0.20.20.2-0.20.40.50.30.90.10.4
Baseline Anxiety0.40.50.90.70.70.60.20.6-0.60.6-0.60.80.90.90.60.90.50.90.6
Tail length0.10.31.2-1.1-1.0-0.80.20.3-0.30.4-0.30.1-0.8-0.0-0.1-0.3-0.2-0.5-0.8
Length with tail0.41.94.1-0.7-0.6-0.31.51.3-1.31.7-1.72.00.31.91.81.71.71.00.7
Length without tail1.13.56.6-0.9-1.0-1.52.51.9-1.92.3-2.22.60.12.52.22.11.51.80.6
Times rat made contact with spout0.50.61.8-1.1-1.2-1.20.4-0.10.1-0.00.1-0.3-1.1-0.1-0.6-0.6-0.7-0.9-1.3
Lifetime Intake1.62.05.52.22.22.3-0.11.0-1.11.0-1.01.01.90.60.91.20.61.61.3
Liver weight, left0.40.61.10.3-0.00.3-1.0-0.80.8-0.80.8-1.0-0.2-0.9-1.0-0.9-0.8-0.9-0.8
Liver weight, right0.40.82.41.50.70.4-1.5-0.40.3-0.50.5-0.80.5-1.0-1.2-0.9-1.0-0.1-1.0
Locomotor activity0.81.34.60.0-0.1-1.5-1.30.2-0.1-0.30.4-0.9-0.7-1.3-1.8-1.0-2.2-0.9-2.1
Locomotor testing distance0.71.35.5-0.1-0.3-1.1-1.00.2-0.1-0.30.3-0.9-0.8-1.3-1.7-1.2-2.3-0.8-2.2
Locomotor testing rearing0.71.55.3-0.4-0.5-1.3-0.80.1-0.1-0.30.4-1.0-1.1-1.5-1.7-1.4-2.3-1.1-2.3
Locomotion in novel chamber0.60.82.11.31.40.9-1.3-0.90.9-1.01.0-0.70.8-1.1-0.7-0.2-0.2-0.10.2
Locomotion in novel chamber post-restriction0.71.12.20.00.0-0.3-1.1-1.51.5-1.51.5-1.4-0.4-1.3-1.1-1.1-0.5-1.0-0.3
Fecal boli incidents, locomotor time 10.30.41.9-0.5-0.9-1.40.20.4-0.40.4-0.40.2-0.5-0.0-0.2-0.5-0.6-0.4-1.2
Change in fecal boli incidents, locomotor task1.51.52.91.71.71.7-1.7-1.21.2-1.31.2-0.71.3-0.6-0.40.11.00.21.3
Time >=10cm from walls, locomotor time 10.30.31.40.91.01.2-0.60.1-0.10.1-0.10.10.9-0.20.20.20.60.40.7
Bouts of movement, locomotor time 12.12.48.7-2.4-2.8-3.01.10.5-0.40.5-0.40.0-2.2-0.3-0.4-0.9-1.4-1.3-2.1
Total resting periods, locomotor time 11.51.76.8-1.9-2.3-2.60.80.4-0.40.4-0.30.1-1.8-0.4-0.3-0.8-1.2-1.1-1.9
Rest time, locomotor task time 10.30.41.20.70.6-0.1-1.1-0.70.7-0.70.7-0.60.3-1.0-0.6-0.6-0.3-0.6-0.3
Distance moved, locomotor task time 10.30.41.8-0.00.31.10.5-0.20.2-0.00.00.10.30.50.70.61.30.71.3
Vertical activity count, locomotor time 10.30.71.90.40.71.4-0.9-1.11.1-1.11.1-1.10.1-0.8-0.8-0.5-0.0-0.20.4
Time >=10cm from walls, locomotor time 20.20.30.6-0.6-0.3-0.1-0.2-0.70.7-0.70.7-0.7-0.4-0.5-0.4-0.70.1-0.7-0.1
Bouts of movement, locomotor time 21.72.76.5-2.2-2.0-1.82.61.9-1.82.0-1.91.5-1.51.51.20.5-0.20.2-0.9
Total resting periods, locomotor time 21.42.55.7-2.0-1.9-1.52.42.0-2.02.1-2.01.4-1.41.41.10.5-0.50.1-1.1
Rest time, locomotor task time 20.10.20.50.70.3-0.1-0.7-0.10.1-0.10.1-0.30.3-0.7-0.5-0.3-0.6-0.4-0.4
Distance moved, locomotor task time 20.60.72.1-0.8-0.30.5-0.0-1.41.4-1.31.3-1.0-0.6-0.6-0.2-0.60.8-0.50.6
Vertical activity count, locomotor time 21.21.74.2-0.5-0.30.7-0.9-2.12.0-2.02.0-1.8-0.7-1.1-1.2-1.30.0-1.1-0.0
Light reinforcement 10.30.62.3-0.3-0.9-0.1-0.4-0.20.2-0.40.5-0.7-0.7-0.9-1.0-1.0-1.5-0.8-1.4
Light reinforcement 20.30.51.81.31.21.1-1.00.4-0.40.2-0.20.51.30.20.20.50.10.50.6
Bone: marrow area1.43.110.03.23.22.5-1.60.4-0.40.4-0.41.03.00.40.61.61.41.31.7
Bone: maximum diameter0.50.91.81.11.10.9-0.11.2-1.21.1-1.11.21.30.40.71.10.70.30.5
Bone: maximum force1.42.54.40.60.50.71.32.0-2.02.0-2.02.11.21.71.81.91.61.31.1
Bone: maximum moment1.32.34.10.50.40.61.31.9-1.92.0-2.02.01.11.61.71.81.41.31.0
Mean time between licks in bursts0.30.71.8-0.5-0.90.71.11.3-1.31.3-1.30.4-0.30.50.6-0.1-0.30.3-0.3
Mean num. licks in bursts0.71.12.3-1.5-1.5-0.80.1-0.40.4-0.50.5-1.2-1.4-0.8-1.1-1.4-1.2-1.4-1.4
Cd content in liver1.11.24.00.50.20.4-0.9-2.02.0-1.71.7-1.30.0-0.9-0.8-0.90.2-0.00.1
Co content in liver1.21.42.4-0.5-0.1-0.1-1.0-1.41.4-1.41.4-1.6-0.7-1.4-1.5-1.3-1.4-1.3-1.0
Cu content in liver0.10.10.3-0.30.30.1-0.50.2-0.20.0-0.0-0.10.2-0.2-0.3-0.1-0.5-0.4-0.3
Fe content in liver0.00.10.1-0.20.30.1-0.00.2-0.20.3-0.20.30.30.30.20.40.10.20.0
K content in liver0.60.61.50.60.50.50.31.2-1.21.1-1.10.90.70.60.50.7-0.10.80.1
Mg content in liver0.30.31.00.40.2-0.1-0.11.0-0.90.7-0.70.40.30.1-0.10.2-0.71.0-0.6
Mn content in liver1.31.52.8-0.4-0.30.51.71.4-1.41.6-1.61.40.21.71.51.21.01.30.7
Na content in liver0.20.20.7-0.8-0.70.10.40.5-0.50.4-0.4-0.1-0.5-0.3-0.2-0.5-0.70.0-0.7
Rb content in liver0.81.02.60.70.50.1-1.6-0.40.4-0.80.8-1.00.1-1.4-1.5-1.1-1.4-0.7-1.2
Se content in liver0.70.81.20.40.41.00.50.9-1.01.1-1.11.10.81.10.90.91.00.90.5
Sr content in liver1.81.65.4-1.6-1.5-0.62.30.9-0.91.3-1.31.2-0.62.01.50.80.70.40.3
Zn content in liver1.41.63.7-1.3-1.0-0.31.71.9-1.91.8-1.81.2-0.71.10.80.6-0.90.8-0.7
Bone: minimum diameter1.52.75.92.42.32.1-1.12.2-2.21.8-1.91.42.20.00.51.30.21.10.2
Time in familiar zone, hab. session 10.60.52.1-0.10.0-0.40.21.5-1.41.1-1.00.7-0.00.1-0.10.1-0.9-0.3-0.9
Time in novel zone, hab. session 11.31.33.90.10.0-0.0-1.0-2.02.0-1.91.8-1.5-0.3-1.2-0.9-1.0-0.1-0.50.3
Total zone transitions, hab. session 10.20.20.9-0.7-1.0-0.70.5-0.10.2-0.10.1-0.2-0.70.1-0.2-0.3-0.5-0.1-0.5
Total locomotion distance, hab. session 10.20.30.60.10.00.10.50.7-0.70.8-0.70.80.20.80.60.70.40.70.2
Locomotion velocity, hab. session 10.30.51.0-0.4-0.5-0.41.00.9-0.91.0-1.00.9-0.20.90.70.60.30.7-0.1
Time in familiar zone, hab. session 21.11.22.3-0.2-0.3-0.6-1.0-1.41.4-1.41.4-1.3-0.6-1.3-1.2-1.2-0.7-1.5-0.8
Time in novel zone, hab. session 20.80.82.0-0.1-0.10.20.91.4-1.41.3-1.30.90.10.80.80.7-0.01.30.3
Total zone transitions, hab. session 20.60.81.8-0.8-1.3-0.80.91.3-1.31.0-1.00.3-0.80.2-0.0-0.2-1.30.2-1.1
Total locomotion distance, hab. session 20.70.92.9-0.2-0.7-0.30.71.7-1.71.5-1.50.8-0.30.50.30.1-0.90.4-0.8
Locomotion velocity, hab. session 20.60.82.80.1-0.4-0.10.51.7-1.71.4-1.40.8-0.10.50.30.2-0.80.5-0.7
Novel to familiar place preference ratio1.21.32.90.10.20.71.01.0-1.01.2-1.21.30.71.61.51.51.71.01.4
Novelty place preference1.11.22.90.30.40.80.70.8-0.81.0-1.01.20.81.41.41.51.70.91.5
Time in novel zone, NPP test1.31.43.40.20.20.61.00.9-0.91.1-1.11.40.71.71.61.61.81.01.6
Total zone transitions, NPP test0.50.82.6-1.3-1.6-1.01.30.8-0.80.8-0.70.2-1.20.20.1-0.4-0.9-0.2-0.9
Total locomotion distance, NPP test0.30.51.4-0.3-0.6-0.10.31.2-1.21.0-1.00.3-0.4-0.0-0.0-0.2-1.10.2-0.8
Locomotion velocity, NPP test0.30.41.9-0.2-0.40.0-0.10.9-0.90.6-0.6-0.1-0.4-0.4-0.4-0.5-1.4-0.1-1.0
Intraocular pressure0.20.30.6-0.7-0.8-0.50.1-0.60.6-0.40.4-0.5-0.5-0.0-0.2-0.6-0.3-0.8-0.2
Delta distance traveled before/after self-admin0.30.30.7-0.2-0.40.4-0.4-0.30.3-0.40.3-0.8-0.4-0.6-0.7-0.7-0.8-0.6-0.6
Delta ambulatory time before/after self-admin0.60.71.4-0.4-0.6-0.1-0.6-1.01.0-1.01.0-1.2-0.7-1.0-1.0-1.1-0.8-1.0-0.7
Parametrial fat weight2.76.424.04.94.73.6-2.40.7-0.80.6-0.61.14.30.30.71.71.82.32.2
Pavlov. Cond. lever latency0.40.51.8-0.20.1-0.3-0.4-1.31.3-1.01.1-0.50.1-0.1-0.3-0.10.5-0.60.3
Pavlov. Cond. magazine entry latency0.30.41.00.1-0.3-0.11.00.7-0.70.7-0.70.80.10.60.80.60.31.00.3
Pavlov. Cond. change in total contacts0.30.31.0-0.2-0.5-0.00.61.0-1.00.8-0.80.3-0.40.10.0-0.1-1.00.4-0.7
Pavlov. Cond. index score0.10.10.3-0.2-0.5-0.40.60.6-0.60.4-0.40.3-0.3-0.00.1-0.0-0.40.2-0.4
Pavlov. Cond. latency score0.10.10.30.1-0.3-0.20.30.5-0.50.3-0.30.2-0.2-0.10.0-0.1-0.50.3-0.3
Pavlov. Cond. lever contacts0.20.20.80.40.10.50.10.9-0.90.6-0.70.30.1-0.10.1-0.0-0.40.5-0.3
Pavlov. Cond. magazine entry number0.10.20.80.70.80.5-0.9-0.00.0-0.10.1-0.20.5-0.3-0.4-0.1-0.00.1-0.0
Pavlov. Cond. intertrial magazine entries1.31.55.3-0.9-1.1-1.40.01.0-1.00.4-0.4-0.5-1.5-1.1-1.2-1.2-2.3-1.2-2.2
Pavlov. Cond. lever-magazine prob. diff.0.20.20.6-0.2-0.6-0.30.70.8-0.80.6-0.60.3-0.40.00.2-0.0-0.50.3-0.4
Pavlov. Cond. response bias0.30.30.8-0.4-0.7-0.10.90.9-0.90.8-0.80.5-0.40.20.40.1-0.20.2-0.3
Pavlov. Cond. lever latency1.01.33.30.50.50.8-1.5-1.81.8-1.61.6-1.40.1-1.2-1.0-1.10.4-0.30.1
Pavlov. Cond. magazine entry latency3.54.210.6-2.4-1.8-1.53.32.6-2.62.6-2.62.3-0.82.32.11.50.40.50.1
Pavlov. Cond. change in total contacts1.21.94.0-1.5-1.1-1.62.02.0-2.01.8-1.81.4-0.91.01.00.8-0.4-0.1-0.5
Pavlov. Cond. index score2.53.37.3-1.6-1.1-1.52.72.4-2.42.4-2.42.3-0.42.11.91.70.50.50.2
Pavlov. Cond. latency score2.53.36.7-1.4-0.9-1.32.62.4-2.42.4-2.42.3-0.22.12.01.80.50.70.3
Pavlov. Cond. lever contacts1.01.43.2-0.9-0.8-1.21.61.8-1.71.6-1.61.3-0.41.10.90.9-0.5-0.0-0.4
Pavlov. Cond. magazine entry number4.96.115.52.82.01.8-3.9-2.82.7-3.13.0-2.90.8-3.1-2.8-2.1-1.3-0.7-0.5
Pavlov. Cond. intertrial magazine entries1.52.24.61.00.2-0.3-1.7-2.12.1-2.12.1-1.8-0.2-1.7-1.8-1.5-0.7-0.7-0.8
Pavlov. Cond. lever-magazine prob. diff.2.63.58.1-1.8-1.3-1.62.82.4-2.42.4-2.42.3-0.62.12.01.70.40.50.1
Pavlov. Cond. response bias2.02.75.9-1.4-1.0-1.12.42.4-2.42.3-2.31.9-0.41.81.61.4-0.00.4-0.0
Time in closed arm before self-admin0.20.20.40.60.60.5-0.5-0.60.6-0.60.6-0.20.4-0.50.00.00.30.00.6
Time in closed arm after self-admin0.20.30.80.70.7-0.4-0.9-0.00.1-0.20.2-0.20.3-0.7-0.6-0.3-0.7-0.3-0.6
Time in open arm before self-admin0.70.81.90.50.70.3-1.3-0.80.8-1.01.0-1.20.1-0.8-1.4-0.9-1.2-0.7-0.7
Time in open arm after self-admin0.10.10.6-0.8-0.60.10.50.3-0.30.3-0.3-0.1-0.60.2-0.1-0.2-0.4-0.2-0.3
Bone: periosteal estimation0.91.94.22.12.01.5-0.61.4-1.51.3-1.31.42.00.50.71.40.90.90.6
Bone: periosteal perimeter0.20.41.11.00.90.4-0.40.7-0.70.6-0.60.71.0-0.00.20.60.40.4-0.0
Bone: post-yield work2.13.08.12.62.62.1-0.80.8-0.80.7-0.81.42.81.01.21.91.81.92.1
Progressive ratio test 1 active lever presses0.30.41.90.91.01.4-0.10.2-0.20.2-0.20.20.80.10.40.40.40.60.9
Progressive ratio test 1 breakpoint0.30.31.60.90.91.3-0.10.1-0.20.2-0.20.20.80.10.40.40.40.60.9
Progressive ratio test 1 inactive lever presses1.82.65.10.10.20.21.82.2-2.22.3-2.22.10.71.81.81.81.01.60.8
Progressive ratio test 2 active lever presses0.60.72.31.51.51.2-0.50.9-0.90.7-0.70.51.20.00.30.6-0.20.70.5
Progressive ratio test 2 breakpoint0.70.82.51.51.61.3-0.41.0-1.00.8-0.80.61.30.10.40.7-0.10.80.5
Progressive ratio test 2 inactive lever presses0.71.22.81.41.50.80.01.7-1.71.4-1.41.21.10.20.51.0-0.31.00.1
Incentive Sensitization - Responses1.21.73.00.60.70.40.91.7-1.71.7-1.71.61.01.41.41.40.81.30.9
Incentive Sensitization - Breakpoint1.41.83.30.80.90.50.81.8-1.81.7-1.81.71.11.41.41.50.81.30.9
Sum of active levers in priming session hrs 5-60.80.72.3-1.4-1.5-1.11.00.6-0.60.5-0.5-0.0-1.2-0.0-0.2-0.5-0.9-0.5-1.0
Progressive ratio0.81.23.31.00.91.80.10.9-0.91.0-1.01.01.20.71.21.01.51.11.2
Food seeking constrained by brief footshock0.10.11.5-0.2-0.11.2-0.20.3-0.30.2-0.2-0.1-0.2-0.2-0.2-0.3-0.2-0.2-0.4
Seeking ratio, punishment vs. effort0.20.31.4-0.5-0.3-0.4-0.00.0-0.0-0.10.1-0.3-0.5-0.1-0.7-0.4-1.2-0.4-1.0
Retroperitoneal fat weight1.35.827.95.34.72.9-3.60.3-0.4-0.0-0.00.14.1-0.8-0.70.70.51.20.9
Reaction time number correct0.91.710.8-1.1-1.2-3.30.2-1.92.0-1.51.5-0.6-0.70.0-0.1-0.30.8-0.70.2
Reaction time mean minus median0.41.02.6-1.4-1.4-1.11.0-1.61.6-1.11.1-0.5-1.30.20.1-0.50.5-0.30.1
Reaction time mean minus median AUC0.92.24.5-1.8-2.0-1.90.7-2.12.1-1.61.7-1.2-2.0-0.5-0.6-1.3-0.1-1.2-0.7
Reaction time num false alarms0.40.51.60.1-0.0-0.6-0.7-0.20.2-0.50.5-0.8-0.3-0.8-1.0-0.8-1.3-1.0-0.9
Reaction time num false alarms AUC0.40.61.8-0.2-0.3-0.7-0.4-0.40.4-0.60.6-0.9-0.6-0.7-1.0-0.8-1.3-1.0-0.9
Reaction time trials correct on left0.91.710.8-1.1-1.2-3.30.2-1.92.0-1.51.5-0.6-0.70.0-0.1-0.30.8-0.70.2
Reaction time trials on left1.01.911.6-1.1-1.3-3.40.2-2.02.1-1.61.6-0.6-0.8-0.0-0.2-0.30.8-0.80.2
Reaction time mean0.50.72.0-1.2-1.2-0.20.7-1.01.0-0.80.8-0.8-1.4-0.4-0.4-1.0-0.4-0.7-0.6
Reaction time mean AUC0.40.71.8-1.0-1.0-0.00.4-1.01.0-0.80.8-0.9-1.4-0.5-0.5-1.1-0.6-0.8-0.7
Median of all reaction times0.20.20.9-0.8-0.80.30.6-0.40.4-0.20.2-0.4-1.0-0.2-0.1-0.6-0.4-0.3-0.4
Reaction time omissions0.50.81.8-1.0-1.2-1.40.6-1.31.4-1.01.1-0.6-0.9-0.0-0.3-0.60.1-0.6-0.5
Reaction time false alarm rate0.40.52.30.70.61.2-0.60.9-0.90.4-0.5-0.30.2-0.6-0.7-0.4-1.5-0.3-0.8
Reaction time premature initiation rate2.73.76.00.61.01.51.61.9-2.02.2-2.22.51.32.12.42.42.12.01.8
Reaction time premature initiations1.01.74.3-0.6-0.1-0.71.70.6-0.61.1-1.11.80.41.81.91.82.11.11.4
Std. dev. reaction times1.01.94.1-1.5-1.5-1.00.3-2.02.0-1.61.7-1.4-1.8-0.8-0.9-1.4-0.6-1.1-0.9
Reaction time trials completed1.01.911.6-1.1-1.3-3.40.2-2.02.1-1.61.6-0.6-0.8-0.0-0.2-0.30.8-0.80.2
Reaction time trials AUC0.91.711.3-1.0-1.2-3.40.2-1.91.9-1.51.5-0.6-0.7-0.0-0.2-0.30.7-0.70.1
Run reversals in cocaine runway, females1.21.22.51.41.51.00.30.6-0.60.7-0.71.01.41.11.01.31.11.61.3
Run reversals in cocaine runway, males0.80.81.90.60.50.9-1.4-0.50.5-0.90.8-1.30.1-1.2-1.2-1.0-1.2-0.6-0.4
Latency to leave start box in cocaine runway1.31.55.12.22.01.9-1.10.3-0.40.3-0.30.52.00.30.50.81.01.11.3
Latency to leave start box in cocaine runway, F0.70.81.21.11.10.8-0.11.1-1.11.0-1.00.91.10.70.70.80.40.80.7
Latency to leave start box in cocaine runway, M1.61.53.61.91.51.8-1.8-1.21.2-1.11.1-0.71.4-0.8-0.4-0.11.20.21.0
Std. dev. time between licks in bursts0.20.21.00.20.40.9-0.50.5-0.50.3-0.4-0.20.3-0.5-0.4-0.4-1.0-0.2-0.5
Total sessions with >9 infusions0.30.41.60.70.71.30.1-0.40.3-0.20.1-0.10.70.30.50.30.90.61.1
Short access day 1 total inactive lever presses0.40.52.11.01.01.5-0.10.6-0.60.6-0.60.50.90.40.50.60.60.70.6
Short access day 10 total inactive lever presses0.20.41.0-0.9-0.8-0.60.00.1-0.10.0-0.0-0.4-0.9-0.7-0.5-0.7-0.6-1.0-0.9
Short access day 1 total infusions0.30.41.81.11.11.4-0.7-0.40.3-0.40.3-0.30.8-0.3-0.1-0.10.20.20.6
Short access day 10 total infusions1.82.36.11.91.92.50.31.1-1.11.2-1.21.31.91.01.41.51.01.81.7
Short access total infusions1.01.34.01.81.72.0-0.00.3-0.40.4-0.50.71.60.70.91.00.91.31.6
Short access day 1 locomotion0.20.31.10.60.61.1-0.20.7-0.70.5-0.60.20.50.00.10.2-0.50.30.1
Short access day 10 total locomotion1.22.23.80.81.01.61.11.5-1.51.6-1.61.61.31.71.71.71.12.01.5
Short access total locomotion1.21.42.41.01.11.60.71.3-1.31.2-1.31.11.21.21.21.30.61.51.1
One hour access (0.3 mA shock)1.31.53.91.92.01.8-0.71.4-1.41.1-1.10.91.60.20.41.0-0.31.00.5
Compulsive drug intake0.60.83.0-1.7-1.7-1.70.8-0.50.5-0.20.3-0.1-1.20.50.2-0.20.4-0.6-0.2
One hour access (shock baseline)1.21.86.92.62.62.4-1.80.5-0.60.1-0.1-0.11.8-1.0-0.60.1-0.90.50.2
Social response proportion0.30.30.90.50.7-0.3-0.9-0.80.8-0.90.8-0.60.4-0.5-0.5-0.2-0.1-0.00.2
Social responses0.50.71.4-0.6-0.1-0.9-0.7-0.40.4-0.60.6-1.0-0.6-0.9-1.1-1.0-1.2-1.0-1.0
Social time1.11.52.2-1.5-1.3-1.3-0.2-1.41.5-1.41.4-1.4-1.4-0.9-1.1-1.3-0.7-1.2-0.9
Soleus weight1.13.38.80.80.9-0.6-2.6-0.80.9-1.61.5-2.1-0.5-3.0-2.7-2.1-2.4-2.0-2.0
Bone: stiffness0.30.50.90.50.50.50.31.0-1.00.9-0.90.90.80.50.60.80.50.30.3
Tibialis anterior weight2.68.730.1-2.9-3.2-2.95.52.4-2.43.2-3.13.2-1.53.93.32.31.81.80.5
Time to tail flick, vehicle, before self-admin1.01.03.10.90.91.20.40.1-0.10.4-0.40.81.21.01.21.11.81.21.6
Time to tail flick, vehicle, after self-admin0.81.14.20.30.20.20.90.3-0.30.7-0.71.10.71.31.51.22.01.21.5
Time to tail flick, test, before self-admin1.11.12.91.51.70.70.00.7-0.70.7-0.71.11.50.70.91.30.91.31.0
Time to tail flick, test, after self-admin0.10.10.4-0.5-0.4-0.30.10.0-0.0-0.00.0-0.2-0.5-0.6-0.3-0.4-0.3-0.5-0.5
Delta time to tail flick, vehicle, before/after SA0.30.30.8-0.7-0.8-0.90.60.5-0.50.6-0.60.5-0.60.40.40.30.00.1-0.4
Delta time to tail flick, test, before/after SA1.61.74.8-2.1-2.2-1.00.40.3-0.30.1-0.1-0.8-2.0-0.9-0.9-1.4-1.6-1.5-1.7
Tibia length0.41.22.7-0.4-0.1-0.41.40.8-0.71.0-1.01.50.31.41.41.31.51.60.7
Ambulatory time before self-admin0.50.71.5-0.6-0.3-0.21.21.1-1.01.1-1.01.1-0.21.00.90.80.50.50.2
Ambulatory time after self-admin0.20.20.7-0.20.10.20.40.8-0.80.6-0.60.5-0.00.40.30.3-0.20.2-0.2
Bone: tissue strength0.40.40.90.20.20.2-0.9-0.10.1-0.50.4-0.8-0.1-0.9-1.0-0.7-0.7-0.8-0.6
Total heroin consumption1.72.07.0-2.6-2.5-2.42.40.5-0.40.7-0.70.7-1.81.30.90.30.6-0.1-0.2
Bone: trabecular number0.91.62.40.60.71.01.01.4-1.51.5-1.51.51.11.61.51.40.81.31.1
Bone: trabecular spacing1.82.44.3-1.6-1.6-1.8-0.4-0.80.9-1.11.1-1.5-2.0-1.6-1.7-1.8-1.7-1.7-2.1
Bone: trabecular thickness0.20.21.01.01.00.2-0.60.3-0.30.1-0.10.30.9-0.2-0.10.3-0.50.0-0.1
Bone: trabecular tissue density1.82.65.70.70.70.1-2.4-1.51.5-1.81.8-1.8-0.2-2.3-2.2-1.9-1.7-1.2-1.6
Water consumed over 24 hours0.20.20.5-0.6-0.1-0.50.30.7-0.70.6-0.60.5-0.10.30.00.4-0.3-0.0-0.6
Number of responses in last shaping day0.20.20.4-0.6-0.70.20.70.5-0.50.5-0.50.2-0.40.60.40.2-0.00.20.2