Hub : Genes

RGD1309170

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr2_226707361_226710530 0.03 0.02 7.6e-03 0.01 0.01 0.01 0 2.7e-02 2.7e-02 5.1e-02 7.5e-02
2 BLA gene expression RGD1309170 0.12 0.07 3.3e-04 0.04 0.05 0.06 0.05 2.7e-03 1.2e-03 5.1e-04 7.8e-04
3 NAcc intron excision ratio chr2_226699315_226700385 0.03 0.02 1.4e-03 0.02 0.02 0.01 0.02 2.4e-03 1.1e-03 1.4e-02 5.4e-03
4 NAcc intron excision ratio chr2_226699315_226707297 0.11 0.05 4.0e-13 0.12 0.12 0.12 0.12 1.1e-13 1.6e-13 3.1e-13 7.3e-14
5 NAcc gene expression RGD1309170 0.07 0.04 3.1e-04 0.01 0.04 0.02 0.04 1.2e-02 4.5e-05 8.7e-04 6.2e-05
6 NAcc isoform ratio XM_039102725.1 0.07 0.03 5.1e-08 0.02 0.06 0.06 0.05 8.1e-04 7.2e-08 4.5e-07 9.2e-07
7 NAcc isoform ratio NM_001134579.2 0.06 0.03 9.5e-07 0.02 0.05 0.04 0.04 4.3e-03 1.5e-06 1.5e-05 3.5e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.61.01.91.3-0.1-1.41.10.30.9-0.9
Area under the delay curve0.10.21.0-0.2-1.00.1-0.00.1-0.10.2
BMI with tail0.41.22.8-1.40.91.0-0.3-1.70.8-1.0
BMI without tail0.91.84.6-0.92.21.5-1.4-1.7-0.60.3
Body weight0.93.98.1-2.02.92.3-1.8-2.5-0.60.3
Weight adjusted by age0.20.20.7-0.9-0.00.6-0.2-0.1-0.20.3
Bone surface0.20.41.51.20.3-0.80.6-0.30.4-0.4
Bone volume0.30.51.81.30.9-0.70.2-0.4-0.0-0.0
Breakpoint value in progressive ratio session1.41.62.9-1.0-0.9-0.61.60.81.7-1.7
Number of licking bursts1.01.25.1-2.3-0.90.50.51.10.5-0.5
Context. condit. distance diff. score1.11.32.5-0.7-1.2-0.81.31.61.1-1.1
Locomotion velocity, session 12.12.34.3-1.91.02.1-1.6-1.0-1.41.4
Locomotion distance, session 12.12.79.9-3.20.22.3-1.10.1-1.11.2
Locomotion velocity, session 20.20.20.8-0.9-0.10.60.0-0.3-0.10.2
Locomotion distance, session 23.34.711.9-3.50.23.0-1.9-0.2-1.92.1
Locomotion velocity, session 31.82.13.5-1.91.01.7-1.40.2-1.61.6
Locomotion distance, session 30.20.20.9-0.9-0.50.30.10.7-0.00.1
Stereotopy head waving bouts, day 31.41.62.6-0.91.41.4-1.6-0.7-1.31.3
Stereotopy head waving duration, day 31.21.42.5-1.01.61.3-1.4-0.6-1.11.0
Locomotion velocity, session 70.70.83.4-1.90.21.2-0.6-0.1-0.20.2
Locomotion distance, session 71.21.54.9-2.2-1.50.40.71.20.8-0.8
Stereotopy head waving bouts, day 72.32.65.10.62.31.0-1.9-0.9-2.01.9
Stereotopy head waving duration, day 73.44.16.70.32.51.4-2.4-0.8-2.62.6
Locomotion velocity, session 80.20.21.0-1.0-0.40.6-0.20.3-0.20.2
Locomotion distance, session 81.82.713.4-3.7-0.91.8-0.31.1-0.30.5
Degree of sensitization distance1.11.11.8-0.7-1.3-0.51.20.61.3-1.3
Degree of sensitization stereotypy2.52.85.71.12.40.8-1.8-1.2-1.91.9
Conditioned locomotion1.01.14.32.10.7-0.3-0.8-1.1-0.80.8
Cocaine response after cond. corrected0.30.30.80.70.80.0-0.4-0.9-0.20.1
Cocaine response after cond. not corrected0.40.51.51.20.1-0.40.2-1.20.4-0.4
Cocaine response before conditioning0.20.20.60.2-0.8-0.20.4-0.40.5-0.4
Saline control response2.22.85.4-1.01.31.8-1.9-0.1-2.32.3
Bone: connectivity density1.52.33.61.1-1.4-1.91.91.31.4-1.4
Bone: cortical apparent density0.20.21.0-1.00.30.5-0.00.3-0.00.0
Bone: cortical area0.40.62.70.11.70.3-0.4-1.20.1-0.3
Bone: cortical porosity1.11.21.8-0.51.01.3-1.4-0.9-1.31.3
Bone: cortical porosity1.21.32.1-0.61.11.3-1.4-1.2-1.11.1
Bone: cortical thickness0.30.52.20.11.50.10.1-0.90.4-0.6
Bone: cortical thickness0.70.83.50.81.10.2-0.3-1.90.2-0.3
Bone: cortical tissue density0.20.21.1-1.10.20.50.00.30.0-0.0
Condit. Reinf. active minus inactive responses1.72.07.7-2.80.71.9-1.00.0-0.70.7
Condit. Reinf. active-inactive response ratio2.42.510.2-3.21.02.2-1.1-0.4-0.50.5
Condit. Reinf. active responses1.21.43.9-2.00.41.6-1.10.0-1.01.1
Condit. Reinf. inactive responses0.40.41.51.20.2-0.2-0.5-0.2-0.70.8
Incentive salience index mean0.70.83.5-1.90.41.3-0.6-0.1-0.30.3
Condit. Reinf. lever presses0.10.10.2-0.00.40.2-0.40.0-0.30.3
Condit. Reinf. active minus inactive responses0.30.41.11.10.9-0.60.2-0.50.3-0.4
Condit. Reinf. active-inactive response ratio0.40.40.70.50.5-0.70.70.10.7-0.8
Condit. Reinf. active responses0.30.41.10.80.9-0.30.2-1.00.3-0.5
Condit. Reinf. inactive responses0.30.31.0-0.30.50.7-0.5-1.0-0.30.3
Condit. Reinf. lever presses0.30.50.80.80.2-0.50.4-0.80.8-0.9
Condit. Reinf. lever reinforcers received0.30.41.00.90.8-0.30.2-1.00.4-0.5
Conditioned reinforcement - actives1.71.72.9-0.71.51.0-1.30.7-1.71.7
Conditioned reinforcement - inactives0.60.71.40.21.00.5-0.90.1-1.11.2
Conditioned locomotion0.60.73.60.4-0.2-0.80.51.9-0.30.4
Patch foraging indifference point 0 sec1.11.74.5-0.4-2.1-0.91.51.90.8-0.6
Patch foraging indifference point AUC0.10.10.4-0.10.3-0.20.3-0.00.5-0.6
Delay disc. indifference point, 0s delay0.50.51.80.6-0.8-0.80.41.3-0.10.1
Delay disc. indifference point, 16s delay0.20.20.6-0.7-0.80.20.10.40.2-0.1
Delay disc. indifference point, 2s delay0.60.62.41.5-0.6-0.90.20.6-0.40.4
Delay disc. indifference point, 24s delay0.40.40.90.9-0.9-0.70.5-0.10.3-0.3
Delay disc. indifference point, 4s delay0.40.41.2-0.0-1.1-0.30.6-0.10.8-0.7
Delay disc. indifference point, 8s delay1.11.12.0-1.1-0.21.4-1.2-0.6-1.11.2
Indifference point function ln k0.60.93.8-2.0-0.51.2-0.50.2-0.50.5
Indifference point function log k0.60.93.8-2.0-0.51.2-0.50.2-0.50.5
Patch foraging total patch changes 0 sec1.01.74.4-0.6-2.1-0.71.51.80.8-0.7
Patch foraging total patch changes 12 sec0.50.71.2-0.4-1.0-0.51.10.41.1-1.1
Patch foraging total patch changes 18 sec1.01.32.6-1.0-1.5-0.51.31.60.9-0.9
Patch foraging total patch changes 24 sec0.30.41.4-1.2-0.00.7-0.20.7-0.50.5
Patch foraging total patch changes 6 sec3.04.57.50.1-2.3-1.82.71.62.5-2.5
Patch foraging time to switch 0 sec0.20.21.01.00.1-0.5-0.20.2-0.40.4
Patch foraging water rate 0 sec0.10.20.5-0.4-0.3-0.10.60.00.7-0.7
Patch foraging water rate 12 sec0.81.22.6-1.60.81.5-1.0-1.0-0.50.4
Patch foraging water rate 18 sec0.50.71.8-0.6-0.6-0.20.8-0.41.2-1.4
Patch foraging water rate 24 sec0.50.83.5-1.9-0.70.70.20.20.6-0.6
Patch foraging water rate 6 sec2.13.011.7-3.40.82.5-0.9-1.4-0.0-0.1
Seeking ratio, delayed vs. immediate footshock1.41.64.32.1-1.3-1.61.10.20.9-0.8
Distance traveled before self-admin0.30.31.40.81.2-0.3-0.2-0.2-0.30.2
Distance traveled after self-admin0.30.40.7-0.2-0.2-0.50.70.70.8-0.8
Extensor digitorum longus weight3.212.427.2-0.65.23.3-3.9-4.7-2.52.1
Bone: elastic displacement0.20.20.7-0.20.80.4-0.4-0.6-0.20.1
Bone: elastic work0.40.51.8-0.21.00.4-0.2-1.30.4-0.6
Bone: endosteal estimation0.10.30.50.10.60.4-0.7-0.6-0.50.4
Bone: endosteal perimeter0.40.81.4-0.11.10.8-1.2-0.5-1.00.9
Epididymis fat weight0.51.22.7-1.60.51.5-1.2-0.4-0.80.8
Delta time in closed arm before/after self-admin2.42.33.7-1.41.11.6-1.80.1-1.91.9
Delta time in open arm before/after self-admin1.31.32.1-0.21.01.1-1.3-0.7-1.51.4
Diff in mean of infusions in LGA sessions2.02.23.7-1.1-1.7-0.61.70.61.9-1.9
Delay discount exponential model param0.10.21.00.21.0-0.20.00.10.0-0.1
Extinction: sum of active levers before priming1.01.02.3-0.2-0.4-0.10.7-1.31.4-1.5
Active lever presses in extinction session 61.21.22.7-0.9-1.2-0.61.21.60.9-0.8
Bone: final force0.10.10.5-0.70.30.20.10.10.3-0.4
Bone: final moment0.10.10.3-0.50.20.10.2-0.10.4-0.5
Food consumed during 24 hour testing period1.01.22.4-1.50.91.5-0.8-1.4-0.30.2
Glucose0.30.41.0-0.90.50.7-0.2-1.00.4-0.4
Heart weight0.71.01.90.11.20.8-1.3-1.4-0.80.7
Delay discount hyperbolic model param0.20.21.2-0.11.10.1-0.2-0.0-0.10.0
Intermittent access intake day 1-15 change0.20.20.50.2-0.3-0.60.60.70.3-0.3
Intermittent access intake escalation0.10.10.30.4-0.1-0.50.30.40.2-0.2
Intermittent access intake escalation 20.20.20.50.50.0-0.70.50.30.5-0.6
Intermitt. access day 1 inactive lever presses0.00.00.2-0.1-0.20.2-0.1-0.50.00.1
Intermitt. access day 15 inactive lever presses1.31.42.9-0.31.31.3-1.3-1.7-0.90.9
Intermitt. access escalation Index0.80.71.51.20.90.0-0.7-1.1-0.60.6
Intermittent access day 1 total infusions1.82.14.0-2.01.42.0-1.4-1.3-0.70.6
Intermittent access day 15 total infusions0.40.51.3-1.20.80.9-0.5-0.5-0.0-0.0
Intermittent access terminal intake (last 3 days)0.70.83.3-1.80.71.1-0.6-0.1-0.20.2
Intermittent access total infusions1.41.64.8-2.21.11.7-1.1-0.8-0.40.3
Intermittent access day 1 locomotion0.50.51.0-1.00.80.9-0.7-0.6-0.30.3
Intermittent access day 15 total locomotion0.20.20.30.3-0.1-0.60.50.50.4-0.4
Intermittent access total locomotion0.20.20.8-0.50.90.3-0.2-0.40.1-0.2
Intermittent access standard deviation0.10.20.5-0.30.2-0.30.30.70.3-0.4
Left kidney weight0.41.13.0-1.70.91.3-0.6-1.20.2-0.3
Right kidney weight0.61.73.0-1.71.51.7-1.4-1.3-0.50.3
Cocaine induced anxiety0.50.62.10.0-1.1-0.60.61.40.00.0
Post-drug Anxiety0.80.82.30.2-1.5-0.81.00.41.0-0.9
Baseline Anxiety1.11.12.50.2-0.7-0.40.9-1.21.5-1.6
Tail length0.41.12.7-0.41.70.9-1.2-0.5-1.11.0
Length with tail0.31.23.60.11.90.8-1.0-1.7-0.40.3
Length without tail0.30.71.40.80.2-0.60.6-1.11.1-1.2
Times rat made contact with spout1.01.22.5-0.2-1.0-0.51.4-0.31.6-1.6
Lifetime Intake1.72.05.3-2.31.11.9-1.3-0.6-0.80.8
Liver weight, left0.30.41.8-0.7-0.30.1-0.11.4-0.50.5
Liver weight, right0.30.51.4-0.1-0.4-0.70.81.20.6-0.6
Locomotor activity0.20.20.5-0.3-0.6-0.10.5-0.20.7-0.6
Locomotor testing distance0.20.41.4-0.8-0.10.8-0.3-1.20.1-0.1
Locomotor testing rearing1.72.65.3-1.3-1.8-0.01.5-1.02.3-2.3
Locomotion in novel chamber3.84.78.52.6-1.3-2.92.41.12.1-2.1
Locomotion in novel chamber post-restriction0.10.20.60.60.40.00.1-0.8-0.10.2
Fecal boli incidents, locomotor time 10.50.61.1-0.41.10.6-0.70.2-0.91.0
Change in fecal boli incidents, locomotor task0.30.30.7-0.4-0.30.20.1-0.80.7-0.7
Time >=10cm from walls, locomotor time 13.03.04.70.5-1.4-1.92.01.42.2-2.2
Bouts of movement, locomotor time 11.01.12.00.6-1.1-1.01.20.11.4-1.4
Total resting periods, locomotor time 10.50.51.00.2-0.9-0.60.80.11.0-1.0
Rest time, locomotor task time 10.50.51.41.20.60.0-0.6-0.8-0.80.7
Distance moved, locomotor task time 10.30.30.6-0.8-0.60.10.3-0.10.7-0.7
Vertical activity count, locomotor time 10.50.51.0-0.3-1.0-0.50.70.60.9-0.9
Time >=10cm from walls, locomotor time 21.41.52.5-0.91.11.5-1.6-0.8-1.31.2
Bouts of movement, locomotor time 20.50.61.20.8-1.1-0.90.80.70.3-0.3
Total resting periods, locomotor time 20.70.71.50.9-1.2-1.00.90.70.5-0.4
Rest time, locomotor task time 20.70.83.71.9-0.1-1.00.5-0.40.3-0.3
Distance moved, locomotor task time 20.30.41.0-1.0-0.50.6-0.40.5-0.50.5
Vertical activity count, locomotor time 20.00.00.1-0.1-0.10.1-0.20.2-0.30.3
Light reinforcement 10.51.04.5-2.10.21.4-0.4-0.6-0.10.1
Light reinforcement 20.00.00.30.1-0.00.10.0-0.50.1-0.1
Bone: marrow area0.10.20.40.10.50.3-0.6-0.6-0.40.4
Bone: maximum diameter0.10.20.80.30.90.0-0.1-0.6-0.0-0.1
Bone: maximum force0.10.10.3-0.50.4-0.00.20.50.1-0.2
Bone: maximum moment0.00.10.2-0.20.2-0.20.30.20.3-0.4
Mean time between licks in bursts0.40.61.4-0.7-1.0-0.40.71.20.6-0.6
Mean num. licks in bursts0.91.14.02.00.2-0.80.4-1.40.6-0.6
Cd content in liver0.10.10.4-0.6-0.10.10.10.20.4-0.4
Co content in liver2.32.74.6-2.01.52.1-1.7-0.9-1.41.4
Cu content in liver2.93.56.3-0.2-2.5-1.62.32.01.9-1.7
Fe content in liver1.51.83.11.4-1.4-1.81.51.40.8-0.7
K content in liver1.41.42.11.4-1.0-1.41.40.41.1-1.1
Mg content in liver0.50.51.00.2-1.0-0.61.00.40.8-0.8
Mn content in liver0.70.81.40.90.2-0.70.7-0.91.1-1.2
Na content in liver0.00.00.20.20.30.1-0.1-0.4-0.10.1
Rb content in liver0.50.71.8-1.30.21.0-0.60.5-0.80.8
Se content in liver0.40.51.01.0-0.5-0.90.70.20.6-0.6
Sr content in liver0.70.62.70.50.60.5-0.9-1.6-0.10.1
Zn content in liver9.510.515.30.7-3.9-3.33.93.63.1-3.0
Bone: minimum diameter1.12.14.3-0.92.11.7-1.6-1.8-0.90.7
Time in familiar zone, hab. session 10.40.40.8-0.10.70.3-0.40.6-0.90.9
Time in novel zone, hab. session 10.20.20.70.8-0.2-0.4-0.1-0.50.3-0.3
Total zone transitions, hab. session 13.44.87.6-2.71.52.8-2.2-0.2-2.42.4
Total locomotion distance, hab. session 10.50.82.2-1.50.21.0-0.50.5-0.90.9
Locomotion velocity, hab. session 10.40.52.3-1.5-0.00.9-0.20.3-0.40.4
Time in familiar zone, hab. session 21.31.33.31.80.8-0.90.5-1.41.0-1.1
Time in novel zone, hab. session 20.90.92.0-1.4-0.80.6-0.21.4-0.70.8
Total zone transitions, hab. session 21.92.46.6-2.60.72.0-1.20.2-1.41.5
Total locomotion distance, hab. session 20.30.41.8-1.3-0.10.8-0.1-0.20.1-0.1
Locomotion velocity, hab. session 20.20.31.7-1.3-0.30.7-0.0-0.00.1-0.0
Novel to familiar place preference ratio0.20.20.8-0.9-0.50.30.1-0.10.4-0.3
Novelty place preference0.30.30.8-0.9-0.60.30.2-0.20.6-0.5
Time in novel zone, NPP test0.30.30.6-0.8-0.60.30.2-0.30.6-0.6
Total zone transitions, NPP test1.62.27.0-2.60.92.1-1.1-0.4-1.01.0
Total locomotion distance, NPP test0.30.41.7-1.3-0.40.30.50.30.6-0.6
Locomotion velocity, NPP test0.40.51.9-1.4-0.40.30.60.10.8-0.8
Intraocular pressure0.40.61.81.30.6-0.3-0.50.0-0.90.9
Delta distance traveled before/after self-admin0.70.82.2-1.2-1.50.10.50.80.7-0.7
Delta ambulatory time before/after self-admin0.91.02.5-1.4-1.60.10.70.80.8-0.8
Parametrial fat weight0.61.22.31.1-1.0-1.51.11.30.8-0.8
Pavlov. Cond. lever latency0.60.82.1-0.60.91.1-1.1-1.4-0.40.3
Pavlov. Cond. magazine entry latency0.50.61.2-0.60.50.9-1.1-0.2-1.01.0
Pavlov. Cond. change in total contacts0.30.30.8-0.9-0.60.3-0.00.9-0.30.4
Pavlov. Cond. index score0.20.30.40.5-0.6-0.70.60.60.3-0.3
Pavlov. Cond. latency score0.40.50.80.6-0.8-0.90.80.80.4-0.4
Pavlov. Cond. lever contacts0.40.50.80.7-0.5-0.90.80.60.6-0.6
Pavlov. Cond. magazine entry number0.60.71.10.9-0.5-1.01.00.11.0-1.0
Pavlov. Cond. intertrial magazine entries0.20.20.70.2-0.1-0.60.50.80.2-0.2
Pavlov. Cond. lever-magazine prob. diff.0.20.30.50.4-0.7-0.60.60.40.5-0.5
Pavlov. Cond. response bias0.20.30.5-0.40.30.4-0.60.3-0.70.7
Pavlov. Cond. lever latency0.20.20.60.8-0.6-0.60.40.30.10.0
Pavlov. Cond. magazine entry latency0.10.10.50.70.4-0.2-0.3-0.0-0.30.3
Pavlov. Cond. change in total contacts0.10.10.3-0.2-0.3-0.30.40.30.5-0.6
Pavlov. Cond. index score0.10.20.70.80.5-0.50.10.00.1-0.2
Pavlov. Cond. latency score0.20.20.50.70.0-0.70.40.50.3-0.3
Pavlov. Cond. lever contacts0.40.51.3-0.71.10.8-0.7-0.8-0.20.1
Pavlov. Cond. magazine entry number0.20.20.8-0.9-0.60.50.00.00.00.0
Pavlov. Cond. intertrial magazine entries0.50.61.20.6-0.1-0.50.8-1.01.0-1.1
Pavlov. Cond. lever-magazine prob. diff.0.20.20.70.80.5-0.60.20.10.2-0.2
Pavlov. Cond. response bias0.70.92.4-0.41.60.9-1.1-1.1-0.60.5
Time in closed arm before self-admin0.80.91.9-0.1-0.8-0.91.21.40.9-0.9
Time in closed arm after self-admin1.31.34.2-0.6-1.4-0.81.12.00.6-0.6
Time in open arm before self-admin0.60.63.3-0.20.50.5-0.3-1.80.5-0.6
Time in open arm after self-admin2.22.43.8-0.31.61.7-1.9-2.0-1.51.4
Bone: periosteal estimation0.40.82.40.01.50.7-0.8-1.4-0.40.2
Bone: periosteal perimeter0.91.43.30.11.81.0-1.4-1.4-1.00.9
Bone: post-yield work0.40.52.30.2-0.5-0.50.21.5-0.40.5
Progressive ratio test 1 active lever presses2.83.05.7-2.21.52.4-1.8-1.6-1.11.1
Progressive ratio test 1 breakpoint2.02.04.2-2.11.12.0-1.3-1.3-0.80.8
Progressive ratio test 1 inactive lever presses0.60.61.3-0.40.61.0-1.0-1.1-0.60.7
Progressive ratio test 2 active lever presses0.91.02.7-0.71.71.0-1.0-1.2-0.30.2
Progressive ratio test 2 breakpoint1.11.23.1-0.71.81.1-1.0-1.6-0.20.1
Progressive ratio test 2 inactive lever presses1.51.74.7-0.42.21.2-1.4-1.1-1.11.1
Incentive Sensitization - Responses0.50.51.41.01.2-0.6-0.20.4-0.40.3
Incentive Sensitization - Breakpoint0.50.51.61.31.2-0.7-0.10.2-0.20.1
Sum of active levers in priming session hrs 5-63.73.66.50.5-1.7-1.72.40.32.6-2.6
Progressive ratio0.70.81.71.21.30.1-0.7-1.2-0.60.5
Food seeking constrained by brief footshock0.20.30.7-0.30.30.00.3-0.60.7-0.8
Seeking ratio, punishment vs. effort0.70.92.2-1.5-1.20.10.70.70.9-0.8
Retroperitoneal fat weight0.10.41.3-0.70.50.8-0.6-1.20.0-0.2
Reaction time number correct0.10.21.1-0.10.20.3-0.1-1.00.2-0.3
Reaction time mean minus median0.50.72.71.71.0-0.6-0.30.1-0.60.6
Reaction time mean minus median AUC0.40.52.41.60.4-0.70.1-0.1-0.20.2
Reaction time num false alarms2.12.85.9-0.51.31.5-2.1-0.2-2.32.4
Reaction time num false alarms AUC2.93.97.3-0.31.91.7-2.5-0.5-2.72.7
Reaction time trials correct on left0.10.21.1-0.10.20.3-0.1-1.00.2-0.3
Reaction time trials on left0.10.21.00.00.20.2-0.1-1.00.2-0.3
Reaction time mean0.50.72.51.61.0-0.5-0.2-1.0-0.10.0
Reaction time mean AUC0.50.71.91.41.2-0.2-0.5-1.3-0.20.2
Median of all reaction times0.40.61.91.11.0-0.1-0.3-1.40.2-0.2
Reaction time omissions0.91.26.32.50.4-1.20.10.1-0.40.5
Reaction time false alarm rate1.52.14.6-0.11.21.0-1.70.2-2.12.1
Reaction time premature initiation rate1.52.03.6-0.91.51.6-1.9-1.0-1.41.4
Reaction time premature initiations2.02.84.7-0.91.91.9-2.2-1.6-1.61.5
Std. dev. reaction times0.60.94.22.10.7-1.10.10.3-0.30.4
Reaction time trials completed0.10.21.00.00.20.2-0.1-1.00.2-0.3
Reaction time trials AUC0.10.20.9-0.10.30.3-0.1-1.00.2-0.2
Run reversals in cocaine runway, females0.40.40.80.1-0.7-0.30.7-0.40.9-0.9
Run reversals in cocaine runway, males0.50.51.2-1.0-0.20.70.0-1.10.5-0.5
Latency to leave start box in cocaine runway0.70.81.7-0.3-1.3-0.51.00.51.0-0.9
Latency to leave start box in cocaine runway, F0.40.41.1-0.6-1.0-0.20.60.70.5-0.4
Latency to leave start box in cocaine runway, M4.24.06.01.3-1.7-2.32.41.22.3-2.3
Std. dev. time between licks in bursts1.72.16.6-2.6-1.90.50.71.80.5-0.3
Total sessions with >9 infusions4.34.78.9-3.01.32.8-2.1-0.1-2.22.3
Short access day 1 total inactive lever presses0.40.41.9-1.4-0.30.8-0.20.2-0.10.2
Short access day 10 total inactive lever presses0.80.81.91.0-1.4-1.00.91.00.3-0.2
Short access day 1 total infusions1.31.33.1-1.8-0.20.9-0.51.6-1.11.2
Short access day 10 total infusions1.92.15.1-2.30.72.1-1.4-0.6-1.11.2
Short access total infusions2.32.67.2-2.70.72.2-1.40.0-1.41.4
Short access day 1 locomotion1.51.65.1-2.1-0.80.50.52.3-0.40.5
Short access day 10 total locomotion0.50.61.2-0.6-0.8-0.41.01.10.7-0.6
Short access total locomotion0.50.51.2-0.9-0.9-0.10.71.10.3-0.3
One hour access (0.3 mA shock)0.20.30.60.20.7-0.30.0-0.30.7-0.8
Compulsive drug intake0.70.72.11.4-0.1-1.00.4-0.60.8-0.9
One hour access (shock baseline)0.10.10.6-0.70.40.4-0.2-0.10.2-0.2
Social response proportion0.20.20.40.70.1-0.1-0.50.3-0.60.6
Social responses0.70.91.60.8-0.7-1.01.1-0.21.2-1.3
Social time1.01.34.52.1-0.3-1.70.70.80.4-0.4
Soleus weight0.82.44.3-0.21.81.5-2.1-1.9-1.41.3
Bone: stiffness0.10.10.6-0.80.50.3-0.00.10.2-0.2
Tibialis anterior weight3.211.128.5-0.44.73.1-3.4-5.3-1.81.4
Time to tail flick, vehicle, before self-admin0.10.10.2-0.10.10.2-0.30.3-0.40.4
Time to tail flick, vehicle, after self-admin0.60.72.31.5-0.1-1.10.40.9-0.40.4
Time to tail flick, test, before self-admin0.70.72.81.7-0.2-1.10.50.6-0.00.1
Time to tail flick, test, after self-admin0.10.20.8-0.9-0.00.4-0.00.3-0.10.1
Delta time to tail flick, vehicle, before/after SA0.20.20.80.2-0.2-0.40.30.9-0.20.2
Delta time to tail flick, test, before/after SA1.31.14.2-2.00.21.5-0.9-0.2-0.60.6
Tibia length0.61.65.51.21.90.4-0.8-2.3-0.20.0
Ambulatory time before self-admin0.30.31.40.71.2-0.2-0.2-0.2-0.20.2
Ambulatory time after self-admin0.30.31.4-0.3-0.2-0.50.41.20.3-0.3
Bone: tissue strength0.40.40.8-0.5-0.6-0.30.60.40.9-0.9
Total heroin consumption0.40.51.00.1-0.5-0.71.00.50.8-0.8
Bone: trabecular number0.30.51.21.10.3-0.90.21.0-0.40.4
Bone: trabecular spacing1.11.43.00.3-1.3-0.81.1-0.41.7-1.7
Bone: trabecular thickness0.81.01.7-0.41.31.0-1.1-0.4-1.21.2
Bone: trabecular tissue density0.50.71.2-0.50.81.0-0.8-0.4-1.11.1
Water consumed over 24 hours0.20.31.2-1.10.40.7-0.1-0.40.0-0.1
Number of responses in last shaping day1.61.72.5-1.60.81.6-1.30.1-1.51.5