Otub1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Otub1 0.04 0.03 1.3e-03 0.01 0 -0 0 5.2e-02 2.2e-01 8.9e-01 2.3e-01
2 OFC gene expression Otub1 0.29 0.14 7.2e-05 0.17 0.1 0.11 0.16 8.4e-05 1.8e-03 1.4e-03 1.2e-04
3 BLA gene expression Otub1 0.7 0.09 0.0e+00 0.47 0.58 0.57 0.57 1.0e-27 5.7e-37 1.4e-36 6.4e-37
4 LHb gene expression Otub1 0.4 0.17 3.1e-06 0.17 0.2 0.2 0.19 8.9e-05 1.7e-05 1.7e-05 3.4e-05
5 IL gene expression Otub1 0.23 0.11 4.6e-04 0.09 0.11 0.09 0.09 3.3e-03 1.3e-03 3.3e-03 3.1e-03
6 NAcc intron excision ratio chr1_204393382_204393587 0.03 0.02 6.5e-03 0.01 0.01 0 0.01 6.6e-03 7.8e-03 1.3e-01 1.9e-02
7 PL gene expression Otub1 0.55 0.12 0.0e+00 0.49 0.55 0.55 0.56 1.6e-60 6.5e-73 3.6e-72 3.2e-74
8 RMTg gene expression Otub1 0.47 0.13 1.6e-10 0.25 0.25 0.23 0.23 2.5e-07 2.0e-07 6.1e-07 6.0e-07
9 Brain gene expression Otub1 0.71 0.11 0.0e+00 0.42 0.53 0.54 0.54 7.8e-42 1.0e-57 3.7e-59 1.6e-59
10 NAcc gene expression Otub1 0.26 0.09 0.0e+00 0.21 0.33 0.34 0.34 2.2e-24 1.1e-39 3.2e-40 4.1e-40
11 Adipose gene expression Otub1 0.5 0.16 0.0e+00 0.17 0.22 0.22 0.21 5.5e-19 5.7e-24 9.3e-24 1.1e-22
12 Liver gene expression Otub1 0.33 0.12 0.0e+00 0.2 0.23 0.22 0.23 3.3e-21 6.1e-25 1.6e-24 2.1e-25
13 pVTA gene expression Otub1 0.5 0.12 0.0e+00 0.41 0.41 0.45 0.45 7.3e-19 2.9e-19 2.5e-21 3.6e-21
14 PL mRNA stability Otub1 0.06 0.04 1.6e-04 0.02 0.03 0.02 0.03 1.9e-03 1.1e-04 3.0e-03 1.8e-04
15 NAcc intron excision ratio chr1_204389105_204393284 0.03 0.02 1.8e-03 0.01 0.02 0.01 0.01 4.2e-02 1.7e-03 5.2e-02 8.6e-03
16 Brain mRNA stability Otub1 0.15 0.07 1.5e-11 0.11 0.12 0.12 0.12 3.5e-10 1.2e-11 3.2e-11 1.9e-11
17 NAcc mRNA stability Otub1 0.08 0.04 3.7e-07 0.06 0.05 0.05 0.06 1.6e-07 1.8e-06 1.1e-06 4.5e-07
18 Adipose mRNA stability Otub1 0.08 0.05 3.6e-07 0.04 0.04 0.04 0.05 9.8e-06 8.0e-06 3.5e-05 3.3e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density1.01.73.50.40.5-1.2-1.3-1.30.9-1.1-1.3-1.41.5-1.0-1.60.71.51.51.8-1.91.5
Area under the delay curve0.40.40.90.20.3-0.6-0.4-0.50.5-0.7-0.8-0.50.6-0.8-0.90.60.40.80.8-0.90.8
BMI with tail5.718.430.72.92.7-4.3-4.7-4.61.7-4.5-4.8-4.95.1-4.0-5.53.63.13.55.0-5.34.8
BMI without tail3.16.410.82.62.2-2.7-2.6-2.80.4-2.9-3.0-2.93.0-2.9-3.32.60.81.32.2-3.12.0
Body weight3.916.325.23.93.9-4.5-5.0-5.0-0.7-4.8-4.8-5.04.9-4.0-4.94.21.11.23.4-4.03.4
Weight adjusted by age1.21.43.01.51.5-1.7-1.7-1.6-1.0-1.4-1.4-1.31.1-0.7-1.10.90.6-0.10.8-0.80.8
Bone surface3.66.310.42.01.8-3.1-3.2-2.90.3-2.6-2.8-2.83.0-2.0-3.01.52.61.72.8-2.82.2
Bone volume1.72.86.50.70.7-1.8-2.1-1.71.0-1.4-1.6-1.71.9-0.8-1.90.52.61.82.4-2.11.8
Breakpoint value in progressive ratio session1.21.33.01.71.7-1.5-1.6-1.5-1.2-1.4-1.2-1.21.1-0.9-1.00.80.2-0.60.3-0.50.1
Number of licking bursts0.10.10.30.60.3-0.6-0.5-0.4-0.3-0.4-0.4-0.40.3-0.3-0.30.20.3-0.00.2-0.10.2
Context. condit. distance diff. score0.40.51.3-0.8-1.01.00.90.91.10.80.70.7-0.60.70.4-0.50.20.80.20.00.4
Locomotion velocity, session 10.30.41.10.40.4-0.5-0.2-0.50.4-0.7-0.7-0.70.7-1.1-0.90.9-0.10.50.4-0.70.5
Locomotion distance, session 11.31.73.10.60.8-1.1-1.1-1.20.8-1.3-1.4-1.61.5-1.4-1.71.30.71.21.5-1.81.5
Locomotion velocity, session 22.22.64.11.71.8-1.9-2.0-2.0-0.5-2.0-1.9-1.91.9-1.6-1.91.70.40.31.2-1.31.1
Locomotion distance, session 20.91.33.10.71.0-1.2-0.9-1.10.1-1.4-1.4-1.41.4-1.8-1.51.4-0.00.50.7-1.20.8
Locomotion velocity, session 31.61.96.4-0.5-0.50.1-0.6-0.52.3-0.4-0.6-0.90.9-0.2-1.30.51.52.42.3-2.02.5
Locomotion distance, session 30.10.20.6-0.1-0.00.0-0.2-0.20.5-0.2-0.2-0.40.3-0.2-0.50.30.20.60.6-0.40.8
Stereotopy head waving bouts, day 31.11.44.9-0.7-0.70.2-0.1-0.12.0-0.2-0.4-0.50.6-0.3-1.00.31.32.21.8-1.91.9
Stereotopy head waving duration, day 30.50.62.0-0.9-1.10.70.50.51.40.50.40.3-0.20.4-0.1-0.40.81.30.8-0.70.9
Locomotion velocity, session 70.80.83.1-0.8-0.80.60.10.21.70.40.20.00.10.4-0.2-0.41.11.61.3-1.31.5
Locomotion distance, session 70.30.41.3-0.30.1-0.2-0.1-0.20.8-0.3-0.5-0.50.5-0.6-0.60.60.20.90.7-1.01.2
Stereotopy head waving bouts, day 70.30.41.4-0.1-0.90.4-0.00.21.10.50.30.20.00.70.0-0.71.20.90.9-0.30.5
Stereotopy head waving duration, day 70.60.71.81.10.5-0.8-1.3-1.10.1-0.8-0.8-1.01.1-0.3-0.90.40.90.41.1-0.70.7
Locomotion velocity, session 81.31.55.11.41.5-1.5-0.7-1.1-0.4-1.5-1.5-1.41.3-2.2-1.41.6-0.5-0.10.1-1.0-0.1
Locomotion distance, session 80.60.93.10.0-0.3-0.3-0.2-0.31.7-0.4-0.6-0.60.7-0.8-1.00.31.21.81.4-1.51.3
Degree of sensitization distance0.50.51.6-0.1-0.1-0.3-0.3-0.30.9-0.3-0.5-0.30.5-0.3-0.60.30.81.21.0-1.21.3
Degree of sensitization stereotypy0.20.31.10.60.0-0.4-0.8-0.60.3-0.2-0.3-0.40.60.1-0.4-0.21.00.40.8-0.40.4
Conditioned locomotion1.11.32.31.51.3-1.5-1.2-1.3-0.6-1.4-1.4-1.41.4-1.4-1.31.3-0.1-0.10.5-0.70.5
Cocaine response after cond. corrected0.30.41.5-1.2-0.80.91.00.71.10.50.40.3-0.4-0.00.1-0.0-0.20.70.1-0.30.3
Cocaine response after cond. not corrected0.20.31.2-1.1-0.60.60.70.51.00.30.20.1-0.3-0.2-0.10.1-0.10.70.2-0.50.3
Cocaine response before conditioning0.20.20.60.40.7-0.7-0.8-0.6-0.8-0.5-0.4-0.30.3-0.1-0.20.10.2-0.5-0.0-0.2-0.3
Saline control response2.73.66.52.52.6-2.4-2.2-2.3-1.8-2.3-2.2-2.12.0-1.9-1.72.2-0.5-0.80.4-1.00.5
Bone: connectivity density2.53.96.01.31.6-2.3-2.5-2.30.1-2.1-2.3-2.32.4-1.7-2.31.61.51.22.1-2.22.0
Bone: cortical apparent density0.50.62.30.70.7-0.1-0.0-0.0-1.5-0.00.20.2-0.30.20.60.2-1.2-1.4-1.11.0-1.1
Bone: cortical area0.40.61.60.90.6-0.9-1.3-1.0-0.1-0.7-0.8-0.70.9-0.0-0.70.30.90.41.0-0.61.1
Bone: cortical porosity0.00.10.20.50.1-0.10.10.0-0.1-0.1-0.0-0.20.2-0.4-0.00.1-0.2-0.3-0.30.1-0.5
Bone: cortical porosity0.30.31.01.00.7-0.6-0.3-0.4-0.5-0.6-0.5-0.60.6-0.9-0.40.5-0.4-0.6-0.3-0.1-0.6
Bone: cortical thickness1.52.46.92.32.3-1.5-1.6-1.6-2.6-1.6-1.3-1.31.1-1.0-0.61.6-1.6-1.9-0.80.3-0.4
Bone: cortical thickness0.70.81.80.81.3-0.7-0.5-0.8-1.3-0.9-0.8-0.80.7-1.1-0.51.3-1.3-0.9-0.6-0.0-0.3
Bone: cortical tissue density0.50.72.70.80.8-0.2-0.1-0.1-1.6-0.10.10.2-0.30.10.60.3-1.3-1.5-1.21.1-1.2
Condit. Reinf. active minus inactive responses0.10.11.01.00.5-0.1-0.5-0.4-0.4-0.3-0.1-0.20.30.1-0.10.3-0.2-0.30.1-0.00.1
Condit. Reinf. active-inactive response ratio0.30.30.90.70.20.20.10.2-0.80.10.40.4-0.30.40.5-0.1-0.7-0.9-0.70.8-0.9
Condit. Reinf. active responses0.10.10.40.4-0.00.2-0.4-0.20.3-0.00.00.00.20.5-0.1-0.10.40.30.6-0.20.6
Condit. Reinf. inactive responses0.50.51.7-0.6-0.60.2-0.2-0.11.30.1-0.0-0.10.30.3-0.4-0.31.31.31.2-0.91.1
Incentive salience index mean0.40.51.21.10.6-0.5-0.9-0.8-0.1-0.7-0.6-0.60.8-0.2-0.60.60.30.30.8-0.60.9
Condit. Reinf. lever presses0.50.71.70.60.4-0.7-1.1-0.90.3-0.8-0.8-0.80.9-0.3-0.90.40.90.81.2-1.01.3
Condit. Reinf. active minus inactive responses0.40.41.1-0.5-0.90.60.40.60.90.70.70.7-0.60.80.5-1.10.90.50.2-0.0-0.2
Condit. Reinf. active-inactive response ratio1.41.54.5-1.1-1.61.00.60.92.11.11.00.9-0.71.30.4-1.62.01.61.0-0.40.3
Condit. Reinf. active responses0.00.00.10.3-0.20.1-0.10.00.00.10.10.2-0.20.30.1-0.40.30.00.0-0.0-0.2
Condit. Reinf. inactive responses0.60.72.21.21.0-0.7-0.4-0.7-1.5-0.8-0.7-0.60.4-1.0-0.41.0-1.2-1.0-0.70.0-0.4
Condit. Reinf. lever presses0.91.22.91.20.9-1.5-1.7-1.5-0.4-1.1-1.2-1.21.2-0.6-1.10.41.10.41.1-1.10.7
Condit. Reinf. lever reinforcers received0.00.00.20.50.1-0.2-0.3-0.2-0.3-0.1-0.00.0-0.00.20.0-0.30.3-0.20.00.0-0.3
Conditioned reinforcement - actives0.60.61.5-1.0-0.90.50.80.90.80.90.80.7-0.70.70.7-1.21.00.4-0.10.4-0.6
Conditioned reinforcement - inactives4.85.511.5-2.8-3.02.82.12.51.62.82.72.8-2.53.42.3-2.91.10.7-0.22.0-0.0
Conditioned locomotion7.18.515.0-3.8-3.73.63.03.31.93.63.43.3-3.33.93.1-3.20.50.6-0.82.3-0.4
Patch foraging indifference point 0 sec0.10.21.0-0.0-0.40.60.00.20.10.40.50.4-0.41.00.5-0.4-0.0-0.10.10.50.4
Patch foraging indifference point AUC1.71.94.82.21.9-2.0-2.1-1.8-1.2-1.6-1.4-1.41.7-0.8-1.20.90.5-0.50.6-0.60.4
Delay disc. indifference point, 0s delay1.01.12.7-0.00.3-0.7-0.2-0.51.4-0.8-1.0-1.11.2-1.5-1.41.10.51.41.1-1.70.9
Delay disc. indifference point, 16s delay0.70.72.1-0.8-1.01.00.40.60.70.90.81.0-0.81.40.7-1.00.60.60.40.20.8
Delay disc. indifference point, 2s delay0.40.41.4-0.2-0.0-0.5-0.3-0.31.1-0.4-0.6-0.10.3-0.6-0.70.11.01.21.0-0.90.7
Delay disc. indifference point, 24s delay0.20.10.90.30.4-0.10.0-0.1-1.0-0.2-0.10.1-0.3-0.10.10.4-0.8-0.5-0.40.30.2
Delay disc. indifference point, 4s delay0.50.51.10.60.5-0.4-0.4-0.60.2-0.8-0.8-0.80.8-0.9-0.91.1-0.30.50.6-0.90.8
Delay disc. indifference point, 8s delay0.40.42.20.30.5-0.7-0.1-0.40.2-0.8-0.8-0.80.6-1.5-1.01.0-0.30.40.2-0.80.1
Indifference point function ln k3.14.39.7-3.1-2.73.03.02.72.02.32.22.1-2.31.41.7-1.3-0.90.8-0.80.8-0.3
Indifference point function log k3.14.39.7-3.1-2.73.03.02.72.02.32.22.1-2.31.41.7-1.3-0.90.8-0.80.8-0.3
Patch foraging total patch changes 0 sec0.10.20.60.1-0.20.60.10.2-0.30.30.50.3-0.40.80.5-0.1-0.6-0.5-0.30.70.1
Patch foraging total patch changes 12 sec2.63.47.32.42.3-2.2-2.7-2.5-1.6-2.2-2.0-2.12.2-1.2-1.81.80.1-0.70.9-0.81.1
Patch foraging total patch changes 18 sec0.20.31.31.10.7-0.7-0.9-0.8-0.6-0.6-0.5-0.50.5-0.1-0.30.20.2-0.40.2-0.2-0.1
Patch foraging total patch changes 24 sec1.72.15.32.21.8-1.5-2.3-2.0-1.6-1.6-1.4-1.41.6-0.2-1.21.3-0.0-0.60.8-0.21.4
Patch foraging total patch changes 6 sec0.81.22.01.41.3-1.2-1.4-1.4-0.4-1.3-1.2-1.21.2-0.9-1.21.10.10.10.8-0.81.1
Patch foraging time to switch 0 sec1.93.04.81.01.1-2.1-2.0-1.90.6-1.7-2.0-1.81.9-1.4-1.91.01.91.62.1-2.22.0
Patch foraging water rate 0 sec3.55.59.4-2.2-2.33.12.62.70.12.72.92.9-2.92.82.7-2.0-1.4-1.1-1.92.6-1.5
Patch foraging water rate 12 sec4.87.415.0-2.7-2.83.93.53.30.53.03.33.1-3.22.62.8-1.8-2.2-1.0-2.32.7-1.5
Patch foraging water rate 18 sec1.31.74.1-1.8-1.62.01.91.70.71.51.51.4-1.61.01.2-0.7-1.1-0.0-0.90.8-0.5
Patch foraging water rate 24 sec2.02.85.1-2.3-1.92.22.22.10.61.81.91.9-2.21.31.6-1.1-1.1-0.3-1.31.3-1.0
Patch foraging water rate 6 sec2.33.37.1-2.0-1.62.72.42.20.31.92.22.2-2.11.72.0-1.1-1.8-0.8-1.61.6-1.0
Seeking ratio, delayed vs. immediate footshock0.10.20.5-0.1-0.40.60.30.3-0.10.50.50.4-0.30.70.5-0.1-0.4-0.2-0.20.40.1
Distance traveled before self-admin0.20.31.00.50.3-0.3-1.0-0.7-0.1-0.4-0.2-0.40.50.4-0.3-0.10.70.10.7-0.30.7
Distance traveled after self-admin0.10.10.50.20.10.1-0.2-0.0-0.50.10.20.1-0.00.40.2-0.3-0.0-0.5-0.20.7-0.2
Extensor digitorum longus weight5.321.035.55.55.4-5.6-6.0-5.8-2.3-5.5-5.3-5.45.5-4.2-5.04.70.80.12.9-3.33.1
Bone: elastic displacement1.21.43.2-0.7-0.51.31.51.3-0.51.01.21.1-1.20.51.3-0.2-1.8-1.2-1.61.4-1.3
Bone: elastic work0.81.12.41.31.4-0.9-0.7-0.9-1.3-1.1-1.0-1.00.8-1.2-0.71.5-1.4-1.0-0.5-0.1-0.1
Bone: endosteal estimation1.53.312.1-1.4-1.60.1-0.00.13.40.2-0.3-0.10.50.1-1.1-0.73.13.52.7-2.22.6
Bone: endosteal perimeter1.94.014.1-1.7-2.10.50.20.53.80.70.10.30.20.6-0.8-1.43.73.72.8-2.12.4
Epididymis fat weight1.33.08.0-2.4-2.62.31.31.52.81.81.61.1-1.12.00.8-1.51.32.01.2-0.61.4
Delta time in closed arm before/after self-admin0.40.31.5-0.10.80.1-0.3-0.5-0.2-0.6-0.4-0.60.5-0.3-0.41.2-1.2-0.10.1-0.50.8
Delta time in open arm before/after self-admin0.30.31.40.6-0.20.0-0.5-0.1-0.60.30.30.4-0.41.20.5-0.80.6-0.40.10.60.1
Diff in mean of infusions in LGA sessions0.30.31.50.80.80.2-0.4-0.3-1.0-0.30.20.00.10.40.20.0-1.0-1.2-0.60.4-0.5
Delay discount exponential model param0.30.40.7-0.3-0.40.60.40.5-0.20.70.80.5-0.50.80.8-0.6-0.3-0.6-0.60.8-0.7
Extinction: sum of active levers before priming3.13.16.22.42.0-2.1-2.2-2.1-1.0-2.0-1.9-2.12.5-1.5-1.91.60.4-0.20.9-1.30.7
Active lever presses in extinction session 60.80.72.01.41.4-1.1-1.4-1.2-1.2-0.9-0.7-0.70.8-0.1-0.50.30.2-0.70.20.1-0.0
Bone: final force2.54.06.92.01.8-2.5-2.6-2.5-0.2-2.3-2.3-2.22.4-1.6-2.31.61.30.91.9-1.91.9
Bone: final moment2.23.56.21.91.7-2.3-2.5-2.3-0.2-2.1-2.2-2.12.3-1.5-2.21.51.30.81.8-1.81.8
Food consumed during 24 hour testing period0.20.20.90.1-0.2-0.00.00.2-0.50.40.30.5-0.60.80.7-0.60.2-0.5-0.41.0-0.5
Glucose1.21.86.4-2.3-1.81.01.11.12.51.10.70.7-0.60.50.1-1.01.62.11.1-0.90.8
Heart weight1.42.07.4-2.7-2.02.01.71.61.71.51.41.2-1.41.10.8-0.9-0.11.00.00.20.3
Delay discount hyperbolic model param0.40.50.9-0.4-0.40.70.50.6-0.40.80.80.5-0.60.90.9-0.7-0.3-0.7-0.80.9-0.8
Intermittent access intake day 1-15 change1.11.11.6-0.7-1.11.01.01.2-0.01.21.31.1-1.11.31.2-1.30.2-0.4-0.81.3-1.2
Intermittent access intake escalation0.90.91.6-0.7-1.01.00.81.00.21.11.21.0-1.01.31.0-1.20.2-0.3-0.61.0-0.9
Intermittent access intake escalation 20.70.72.2-0.4-0.70.90.40.7-0.30.91.11.0-1.01.51.0-1.10.1-0.6-0.51.2-0.6
Intermitt. access day 1 inactive lever presses1.71.83.4-1.6-1.81.61.51.61.31.61.51.7-1.41.51.2-1.70.60.6-0.20.7-0.3
Intermitt. access day 15 inactive lever presses2.93.29.3-2.1-2.32.31.11.61.82.12.01.9-1.43.11.5-2.21.31.10.60.90.8
Intermitt. access escalation Index0.90.82.5-1.6-1.21.51.11.00.91.00.90.8-0.80.80.7-0.4-0.40.4-0.10.40.3
Intermittent access day 1 total infusions3.64.115.6-3.0-2.91.81.31.54.01.71.21.1-0.91.50.4-1.72.43.11.9-0.81.8
Intermittent access day 15 total infusions5.46.013.2-3.5-3.62.92.32.63.52.82.52.2-2.12.71.7-2.82.02.10.70.70.3
Intermittent access terminal intake (last 3 days)4.14.412.7-2.9-3.12.21.31.83.62.01.71.5-1.32.40.9-2.32.52.61.6-0.11.2
Intermittent access total infusions3.64.012.3-2.9-2.92.11.41.73.51.91.61.4-1.22.10.9-2.12.32.51.5-0.31.1
Intermittent access day 1 locomotion2.42.511.0-2.3-2.01.20.70.83.30.90.50.3-0.20.8-0.2-0.61.82.82.0-1.12.1
Intermittent access day 15 total locomotion3.33.57.5-2.7-2.72.21.41.72.62.01.81.6-1.52.51.2-2.11.61.70.90.50.9
Intermittent access total locomotion4.75.416.8-3.2-3.22.21.11.64.12.01.61.4-1.02.70.7-2.22.93.22.3-0.62.3
Intermittent access standard deviation1.31.42.3-1.3-1.51.51.31.40.71.41.51.3-1.41.41.2-1.40.1-0.1-0.61.0-0.9
Left kidney weight0.41.23.6-1.9-1.61.40.70.91.21.21.11.0-1.01.50.7-1.20.70.70.50.40.5
Right kidney weight0.30.82.4-1.0-1.30.90.00.41.10.90.70.6-0.51.50.4-1.11.20.80.90.20.8
Cocaine induced anxiety0.10.10.70.2-0.1-0.2-0.3-0.20.2-0.1-0.10.10.20.3-0.2-0.40.80.40.6-0.10.4
Post-drug Anxiety0.50.61.31.10.8-1.0-1.0-0.9-0.4-0.8-0.7-0.91.0-0.4-0.90.30.80.10.6-0.50.2
Baseline Anxiety1.41.52.91.51.6-1.2-1.3-1.3-1.2-1.4-1.2-1.71.4-1.3-1.21.5-0.8-0.8-0.1-0.5-0.0
Tail length0.72.16.02.22.1-1.1-1.1-1.3-2.5-1.3-0.9-0.90.8-1.1-0.41.5-1.9-2.1-1.10.2-0.9
Length with tail1.24.47.92.72.8-2.4-2.7-2.7-2.2-2.5-2.3-2.52.3-1.8-1.92.4-0.9-1.20.4-0.80.7
Length without tail1.12.34.61.21.6-1.7-2.1-2.0-0.9-1.8-1.8-2.12.0-1.2-1.71.60.20.01.2-1.01.3
Times rat made contact with spout0.50.61.71.31.0-0.7-0.4-0.5-1.3-0.7-0.5-0.50.4-0.8-0.20.9-1.1-1.1-0.80.3-0.7
Lifetime Intake2.83.211.4-2.7-2.61.91.31.53.41.61.31.2-1.01.50.5-1.71.82.31.3-0.51.1
Liver weight, left0.20.31.4-0.0-0.30.00.1-0.01.1-0.1-0.2-0.20.3-0.6-0.50.00.40.80.5-1.20.1
Liver weight, right0.71.12.50.50.3-0.5-0.6-0.81.2-0.9-1.0-1.01.1-1.1-1.41.00.51.31.3-1.51.6
Locomotor activity1.11.83.7-1.3-1.31.91.91.6-0.01.31.51.3-1.40.71.3-0.5-1.8-0.8-1.51.0-1.2
Locomotor testing distance1.11.84.2-1.4-1.32.02.01.6-0.01.21.41.3-1.50.61.2-0.3-2.0-0.7-1.50.9-0.9
Locomotor testing rearing0.81.23.3-1.3-1.21.81.71.40.61.11.31.1-1.30.61.0-0.4-1.3-0.3-1.00.5-0.6
Locomotion in novel chamber3.44.29.5-2.6-3.12.41.82.22.12.62.21.9-1.92.71.9-2.51.51.40.40.90.1
Locomotion in novel chamber post-restriction2.22.64.2-2.1-2.12.02.02.01.52.01.91.8-1.71.61.6-1.90.30.5-0.50.8-0.8
Fecal boli incidents, locomotor time 10.20.21.90.0-0.3-0.4-0.3-0.10.60.1-0.00.00.10.3-0.1-0.71.40.60.6-0.30.2
Change in fecal boli incidents, locomotor task0.50.42.60.20.4-0.60.2-0.30.2-0.7-0.8-0.50.5-1.6-0.71.1-0.50.40.0-0.80.2
Time >=10cm from walls, locomotor time 11.41.46.5-1.0-1.40.20.30.42.50.60.20.2-0.00.2-0.3-1.12.42.21.5-1.30.7
Bouts of movement, locomotor time 11.71.87.71.00.8-0.2-0.00.1-2.80.20.40.5-0.50.41.1-0.2-1.6-2.6-2.02.2-2.0
Total resting periods, locomotor time 11.21.35.60.70.6-0.1-0.00.1-2.40.30.50.5-0.50.61.1-0.3-1.2-2.2-1.72.0-1.6
Rest time, locomotor task time 11.71.93.6-0.9-1.31.41.61.60.01.61.51.9-1.71.41.8-1.5-0.5-0.5-1.21.5-1.2
Distance moved, locomotor task time 10.91.02.20.60.4-0.7-0.8-0.90.7-0.9-0.9-1.41.3-1.0-1.51.00.50.81.1-1.30.8
Vertical activity count, locomotor time 10.50.52.0-0.9-1.21.10.90.91.40.80.70.3-0.40.40.2-0.40.30.80.2-0.30.0
Time >=10cm from walls, locomotor time 20.20.20.80.4-0.40.20.20.30.00.40.40.6-0.60.60.6-0.90.5-0.2-0.20.5-0.7
Bouts of movement, locomotor time 20.20.21.10.50.6-0.1-0.5-0.4-1.1-0.2-0.0-0.30.20.30.10.3-0.7-0.9-0.30.5-0.0
Total resting periods, locomotor time 20.10.10.40.20.30.1-0.3-0.2-0.7-0.10.1-0.10.10.40.20.1-0.4-0.6-0.20.40.0
Rest time, locomotor task time 21.41.63.5-1.9-1.81.51.71.61.61.51.31.3-1.30.81.1-1.30.40.9-0.20.1-0.4
Distance moved, locomotor task time 20.70.82.31.51.1-0.9-0.8-0.8-1.3-0.9-0.7-0.90.7-0.9-0.60.8-0.7-1.0-0.40.1-0.6
Vertical activity count, locomotor time 20.60.62.70.30.30.40.60.3-1.10.10.30.3-0.5-0.20.40.3-1.6-1.3-1.40.9-1.3
Light reinforcement 10.30.50.90.1-0.60.90.60.7-0.40.80.90.7-0.70.90.9-0.4-0.7-0.8-0.80.8-0.8
Light reinforcement 21.92.57.0-1.9-2.01.60.91.41.61.91.71.5-1.22.61.5-2.21.81.10.60.60.5
Bone: marrow area1.53.212.0-1.4-1.60.20.10.23.30.2-0.3-0.10.50.1-1.1-0.73.03.52.7-2.22.5
Bone: maximum diameter0.51.04.40.3-0.2-0.7-1.0-0.71.0-0.4-0.6-0.40.80.2-0.8-0.42.11.41.7-1.01.4
Bone: maximum force3.76.510.51.91.7-2.7-3.2-2.90.7-2.5-2.8-2.73.0-1.6-3.01.52.62.13.2-2.93.0
Bone: maximum moment3.35.69.31.71.6-2.5-3.0-2.70.7-2.3-2.6-2.52.8-1.5-2.81.52.41.93.0-2.72.9
Mean time between licks in bursts0.91.23.11.01.5-0.9-0.7-1.0-1.3-1.2-1.0-1.20.9-1.4-0.81.8-1.6-1.0-0.5-0.00.1
Mean num. licks in bursts0.20.30.9-0.1-0.00.50.60.5-0.40.30.50.4-0.40.10.5-0.0-0.9-0.7-0.80.5-0.8
Cd content in liver0.91.02.3-0.6-1.30.91.01.20.91.21.11.3-1.11.10.9-1.50.80.4-0.20.8-0.4
Co content in liver2.42.86.8-0.3-0.51.42.01.7-1.11.21.51.5-1.70.41.8-0.4-2.5-2.0-2.62.3-2.3
Cu content in liver0.10.10.40.60.5-0.3-0.3-0.3-0.5-0.3-0.2-0.10.3-0.2-0.10.2-0.4-0.6-0.30.5-0.3
Fe content in liver0.20.30.80.50.3-0.6-0.5-0.50.5-0.4-0.5-0.30.5-0.4-0.5-0.10.90.60.7-0.70.3
K content in liver2.82.84.71.41.3-1.8-1.9-1.90.4-1.7-1.9-1.92.0-1.5-2.01.51.11.21.8-2.21.8
Mg content in liver0.90.92.70.30.1-0.5-0.9-0.81.1-0.5-0.7-0.80.9-0.2-0.90.41.21.41.6-1.31.6
Mn content in liver0.80.92.71.51.2-1.2-1.6-1.3-0.6-0.9-0.9-1.11.1-0.1-0.70.40.8-0.00.9-0.50.7
Na content in liver0.60.61.31.10.7-1.0-1.1-1.0-0.3-0.8-0.8-0.80.8-0.3-0.70.50.70.30.8-0.70.7
Rb content in liver0.60.82.4-1.3-1.31.11.11.01.51.00.80.8-0.70.50.5-0.80.41.00.2-0.30.2
Se content in liver0.50.62.7-0.5-0.80.3-0.30.20.60.70.50.7-0.41.40.5-1.31.60.60.70.10.4
Sr content in liver1.31.23.21.61.7-1.2-1.6-1.4-1.8-1.1-0.8-0.90.9-0.1-0.40.9-0.4-1.2-0.10.40.1
Zn content in liver0.60.72.20.90.9-0.7-1.5-1.2-0.6-0.8-0.7-0.91.00.1-0.70.70.3-0.10.8-0.21.0
Bone: minimum diameter1.32.58.6-1.2-1.40.3-0.10.12.80.4-0.10.10.30.6-0.7-0.82.72.92.4-1.82.5
Time in familiar zone, hab. session 10.10.10.4-0.3-0.40.40.10.10.40.20.20.1-0.10.40.0-0.20.20.40.4-0.30.6
Time in novel zone, hab. session 10.10.10.5-0.30.10.10.60.40.1-0.00.00.0-0.1-0.70.00.3-0.6-0.1-0.50.3-0.5
Total zone transitions, hab. session 10.30.52.11.50.6-0.8-0.7-0.7-0.2-0.7-0.7-0.80.8-0.7-0.70.60.1-0.00.3-0.20.4
Total locomotion distance, hab. session 10.30.52.0-0.0-0.90.40.20.21.40.30.1-0.10.10.2-0.3-0.21.01.31.0-0.71.1
Locomotion velocity, hab. session 10.10.20.70.5-0.40.1-0.1-0.10.80.0-0.1-0.20.20.1-0.30.00.60.80.7-0.40.8
Time in familiar zone, hab. session 20.50.52.30.40.7-0.30.2-0.1-0.9-0.5-0.3-0.40.2-1.1-0.10.9-1.5-0.9-1.00.1-0.7
Time in novel zone, hab. session 20.30.31.2-0.1-0.2-0.1-0.5-0.20.6-0.0-0.10.00.20.6-0.3-0.31.10.81.0-0.21.0
Total zone transitions, hab. session 21.82.33.91.41.2-1.5-1.6-1.70.2-1.7-1.7-1.91.8-1.6-2.01.60.61.01.5-1.71.7
Total locomotion distance, hab. session 20.70.92.60.50.1-0.4-0.5-0.61.0-0.7-0.8-0.90.9-0.7-1.20.70.71.41.4-1.41.6
Locomotion velocity, hab. session 20.60.82.60.2-0.3-0.2-0.3-0.41.3-0.4-0.6-0.70.7-0.4-1.00.31.01.61.4-1.41.6
Novel to familiar place preference ratio0.50.62.00.20.5-0.9-1.4-1.0-0.1-0.6-0.7-0.70.80.2-0.60.01.20.31.0-0.40.8
Novelty place preference0.30.31.2-0.20.2-0.5-1.0-0.70.1-0.3-0.3-0.30.50.4-0.3-0.31.10.30.8-0.20.6
Time in novel zone, NPP test0.30.31.0-0.20.3-0.5-1.0-0.70.2-0.4-0.3-0.40.50.4-0.4-0.11.00.40.9-0.30.8
Total zone transitions, NPP test1.92.74.21.91.6-2.0-1.9-1.9-0.3-1.9-2.0-2.12.0-1.9-2.01.60.60.51.2-1.51.0
Total locomotion distance, NPP test0.40.61.40.50.0-0.4-0.4-0.50.8-0.6-0.7-0.90.8-0.9-1.00.60.51.11.0-1.21.0
Locomotion velocity, NPP test0.20.30.70.50.0-0.4-0.3-0.40.5-0.4-0.6-0.70.6-0.7-0.80.50.40.70.7-0.80.6
Intraocular pressure2.23.15.9-1.5-1.61.81.41.7-0.42.02.12.2-2.12.42.0-2.1-0.2-1.1-1.42.4-1.5
Delta distance traveled before/after self-admin0.10.20.6-0.0-0.00.00.50.3-0.3-0.0-0.00.1-0.3-0.70.10.3-0.8-0.4-0.70.4-0.7
Delta ambulatory time before/after self-admin0.20.21.20.20.2-0.20.50.2-0.3-0.2-0.3-0.1-0.0-1.1-0.10.5-0.8-0.4-0.70.2-0.7
Parametrial fat weight1.12.19.2-1.9-2.00.80.90.93.00.90.40.3-0.20.4-0.3-0.92.02.61.6-1.01.6
Pavlov. Cond. lever latency0.40.61.7-0.6-0.40.71.11.00.10.70.80.6-0.80.10.7-0.5-0.7-0.5-1.00.8-1.3
Pavlov. Cond. magazine entry latency0.50.62.00.70.3-0.6-1.1-0.90.3-0.6-0.7-0.70.9-0.0-0.80.31.00.71.2-0.91.4
Pavlov. Cond. change in total contacts0.20.31.4-0.4-0.5-0.0-0.4-0.10.30.30.10.3-0.10.80.2-0.71.20.50.7-0.00.6
Pavlov. Cond. index score0.10.10.40.50.2-0.4-0.7-0.5-0.4-0.2-0.3-0.10.30.3-0.0-0.00.3-0.10.3-0.00.4
Pavlov. Cond. latency score0.10.10.40.50.2-0.3-0.7-0.5-0.2-0.3-0.3-0.20.30.2-0.20.10.40.20.5-0.30.7
Pavlov. Cond. lever contacts0.10.20.70.30.2-0.3-0.6-0.5-0.0-0.4-0.4-0.30.4-0.1-0.40.30.20.30.6-0.40.8
Pavlov. Cond. magazine entry number0.10.10.4-0.5-0.20.20.50.30.6-0.0-0.0-0.1-0.0-0.5-0.30.3-0.30.40.0-0.40.0
Pavlov. Cond. intertrial magazine entries1.62.03.9-1.1-1.01.61.21.4-0.41.51.71.8-1.72.01.8-1.5-0.5-1.0-1.21.7-1.2
Pavlov. Cond. lever-magazine prob. diff.0.20.30.90.80.4-0.6-0.9-0.7-0.5-0.5-0.5-0.40.50.0-0.30.20.4-0.00.5-0.20.6
Pavlov. Cond. response bias0.10.10.30.40.1-0.1-0.6-0.3-0.4-0.1-0.10.00.10.50.1-0.20.3-0.10.20.20.4
Pavlov. Cond. lever latency0.40.61.3-0.4-0.30.81.20.9-0.20.60.70.7-0.80.10.8-0.1-1.2-0.7-1.10.9-1.1
Pavlov. Cond. magazine entry latency2.12.44.71.91.9-1.8-2.2-2.0-1.2-1.9-1.7-1.91.8-1.2-1.61.50.0-0.50.7-0.80.7
Pavlov. Cond. change in total contacts0.50.72.50.80.6-1.0-1.6-1.1-0.1-0.7-0.7-0.70.90.3-0.6-0.21.50.41.1-0.50.9
Pavlov. Cond. index score1.21.54.01.11.1-1.5-2.0-1.7-0.4-1.4-1.3-1.41.5-0.5-1.30.71.10.21.2-1.01.1
Pavlov. Cond. latency score1.11.43.61.01.0-1.3-1.9-1.6-0.2-1.3-1.2-1.31.4-0.5-1.30.61.20.51.4-1.11.2
Pavlov. Cond. lever contacts0.10.20.70.30.3-0.5-0.8-0.6-0.4-0.4-0.4-0.40.40.1-0.3-0.00.5-0.10.4-0.20.2
Pavlov. Cond. magazine entry number2.93.68.4-2.4-2.32.32.92.61.32.32.12.2-2.31.21.9-1.6-0.50.4-1.21.0-1.1
Pavlov. Cond. intertrial magazine entries0.60.81.7-0.7-1.21.01.31.20.61.11.01.2-1.10.50.9-1.0-0.00.1-0.60.5-1.0
Pavlov. Cond. lever-magazine prob. diff.1.41.84.61.41.4-1.7-2.2-1.8-0.6-1.5-1.5-1.61.6-0.7-1.40.90.90.11.2-0.91.0
Pavlov. Cond. response bias0.70.92.61.01.0-1.3-1.6-1.4-0.7-1.1-1.0-1.11.1-0.4-0.90.50.6-0.10.7-0.50.6
Time in closed arm before self-admin0.20.21.30.2-0.2-0.6-0.3-0.20.3-0.2-0.3-0.20.3-0.2-0.4-0.31.20.60.6-0.20.2
Time in closed arm after self-admin0.10.10.2-0.4-0.0-0.00.30.20.3-0.0-0.1-0.10.1-0.5-0.10.3-0.10.40.0-0.10.2
Time in open arm before self-admin0.50.53.9-0.30.10.60.90.5-0.30.10.30.1-0.3-0.60.30.8-2.0-0.8-1.10.2-0.7
Time in open arm after self-admin0.70.71.80.0-0.20.70.50.5-1.10.50.70.7-0.80.60.9-0.2-1.3-1.4-1.31.1-1.1
Bone: periosteal estimation1.02.17.4-0.3-0.7-0.5-0.9-0.62.1-0.3-0.7-0.50.90.1-1.2-0.42.72.52.5-1.82.4
Bone: periosteal perimeter0.71.24.10.1-0.3-0.6-0.9-0.61.4-0.5-0.7-0.60.9-0.2-1.0-0.22.01.71.8-1.41.6
Bone: post-yield work3.54.817.0-0.3-0.7-1.2-1.5-1.12.9-0.7-1.3-1.11.6-0.5-2.0-0.54.13.73.6-3.23.0
Progressive ratio test 1 active lever presses2.42.54.8-2.1-2.21.91.91.91.61.91.71.9-1.61.61.4-1.90.60.7-0.30.8-0.5
Progressive ratio test 1 breakpoint2.02.14.3-1.9-2.11.71.81.81.41.81.61.8-1.51.31.3-1.70.60.6-0.40.9-0.6
Progressive ratio test 1 inactive lever presses0.60.61.9-1.4-1.31.30.80.80.70.90.80.7-0.61.00.4-0.5-0.20.3-0.00.70.3
Progressive ratio test 2 active lever presses3.74.07.8-2.6-2.82.31.92.22.42.42.12.2-1.92.51.7-2.51.51.50.40.80.2
Progressive ratio test 2 breakpoint4.95.59.4-2.9-3.12.82.42.72.12.92.72.7-2.42.92.4-2.81.11.0-0.31.4-0.4
Progressive ratio test 2 inactive lever presses6.17.014.8-3.5-3.83.42.32.82.93.12.92.8-2.53.62.1-3.11.51.60.41.40.4
Incentive Sensitization - Responses0.70.82.5-0.9-1.10.90.30.61.00.90.90.7-0.51.60.7-1.11.00.80.60.20.7
Incentive Sensitization - Breakpoint1.01.03.4-1.0-1.31.20.50.81.11.11.10.9-0.71.80.9-1.31.10.80.60.40.7
Sum of active levers in priming session hrs 5-60.50.41.60.60.4-0.2-0.6-0.2-1.30.10.40.3-0.31.00.6-0.90.4-1.1-0.41.0-0.7
Progressive ratio2.63.04.51.81.2-2.1-1.9-1.90.3-1.8-2.0-2.12.1-2.0-2.11.41.31.11.7-2.11.1
Food seeking constrained by brief footshock0.30.41.50.40.8-0.7-0.2-0.5-0.4-0.8-0.8-0.70.5-1.2-0.61.0-0.7-0.3-0.2-0.3-0.1
Seeking ratio, punishment vs. effort1.51.93.0-1.6-0.71.61.71.5-0.31.21.41.5-1.61.11.6-0.6-1.7-1.1-1.61.6-0.9
Retroperitoneal fat weight2.89.221.7-4.7-4.53.93.33.44.13.53.12.8-2.73.02.1-3.01.52.60.60.30.6
Reaction time number correct0.20.31.00.70.6-0.2-0.5-0.5-1.0-0.4-0.3-0.40.5-0.3-0.30.6-0.8-0.8-0.40.1-0.3
Reaction time mean minus median1.31.73.91.71.4-2.0-1.8-1.6-0.5-1.5-1.5-1.51.3-1.3-1.40.71.10.10.8-1.10.1
Reaction time mean minus median AUC0.70.82.31.51.1-1.3-1.1-1.0-0.9-1.1-1.0-1.10.7-1.1-0.80.60.2-0.50.0-0.4-0.5
Reaction time num false alarms0.50.73.6-0.70.10.61.00.6-0.70.30.40.3-0.5-0.40.60.5-1.9-1.0-1.40.8-0.9
Reaction time num false alarms AUC0.50.63.8-0.00.70.00.4-0.0-1.1-0.3-0.1-0.30.1-0.90.11.0-1.9-1.2-1.20.5-0.8
Reaction time trials correct on left0.20.31.00.70.6-0.2-0.5-0.5-1.0-0.4-0.3-0.40.5-0.3-0.30.6-0.8-0.8-0.40.1-0.3
Reaction time trials on left0.20.31.10.80.7-0.3-0.5-0.5-1.1-0.5-0.3-0.50.5-0.3-0.30.6-0.8-0.9-0.40.1-0.4
Reaction time mean0.10.10.5-0.1-0.40.10.00.20.30.20.20.2-0.30.30.0-0.60.70.20.10.1-0.4
Reaction time mean AUC0.10.10.6-0.1-0.50.10.10.20.40.20.20.2-0.30.3-0.0-0.70.80.20.20.1-0.3
Median of all reaction times0.20.20.6-0.5-0.70.50.20.40.60.40.40.4-0.40.60.1-0.80.70.40.30.1-0.0
Reaction time omissions0.40.61.40.70.8-0.9-0.5-0.6-1.1-0.8-0.7-1.10.6-1.2-0.70.8-0.5-0.8-0.5-0.1-0.9
Reaction time false alarm rate0.20.21.4-0.60.10.30.70.4-0.20.10.20.1-0.3-0.50.30.4-1.2-0.4-0.80.4-0.4
Reaction time premature initiation rate2.43.26.62.32.6-1.9-2.0-2.2-1.7-2.2-2.0-1.82.0-1.7-1.72.4-1.1-0.70.4-0.81.1
Reaction time premature initiations3.04.28.92.83.0-2.1-2.2-2.4-2.6-2.4-2.1-2.02.1-1.8-1.72.6-1.7-1.5-0.1-0.50.5
Std. dev. reaction times0.10.20.60.70.5-0.7-0.4-0.3-0.5-0.4-0.3-0.30.2-0.4-0.3-0.20.5-0.3-0.1-0.1-0.8
Reaction time trials completed0.20.31.10.80.7-0.3-0.5-0.5-1.1-0.5-0.3-0.50.5-0.3-0.30.6-0.8-0.9-0.40.1-0.4
Reaction time trials AUC0.20.30.70.60.6-0.2-0.4-0.4-0.9-0.4-0.2-0.50.5-0.3-0.30.6-0.8-0.8-0.30.1-0.2
Run reversals in cocaine runway, females1.91.93.40.61.1-1.2-1.2-1.40.3-1.5-1.6-1.61.6-1.6-1.71.8-0.01.01.3-1.71.8
Run reversals in cocaine runway, males0.10.10.40.5-0.40.10.50.3-0.10.20.10.3-0.2-0.40.0-0.0-0.3-0.1-0.40.2-0.6
Latency to leave start box in cocaine runway0.40.41.6-0.1-0.3-0.1-0.00.01.20.1-0.1-0.10.20.1-0.2-0.31.21.30.9-0.80.9
Latency to leave start box in cocaine runway, F0.10.10.30.10.00.0-0.1-0.00.30.10.10.1-0.10.50.2-0.30.50.40.3-0.10.3
Latency to leave start box in cocaine runway, M0.40.41.4-0.2-0.2-0.40.30.11.2-0.1-0.4-0.30.3-0.9-0.50.01.01.20.6-0.90.2
Std. dev. time between licks in bursts0.20.32.0-0.10.40.00.40.0-0.6-0.3-0.2-0.3-0.1-0.7-0.10.9-1.4-0.6-0.70.3-0.2
Total sessions with >9 infusions1.11.26.3-1.6-1.61.00.90.82.50.80.40.4-0.30.1-0.1-0.51.01.91.0-0.80.8
Short access day 1 total inactive lever presses2.73.06.9-2.6-2.42.41.92.02.02.11.91.9-1.71.91.3-1.70.31.00.00.80.3
Short access day 10 total inactive lever presses2.02.24.6-2.0-1.71.92.21.90.91.81.61.8-1.71.11.5-1.1-0.80.0-1.01.2-0.7
Short access day 1 total infusions1.71.86.5-2.2-2.01.61.31.32.51.31.11.0-0.80.90.4-1.10.81.60.8-0.40.7
Short access day 10 total infusions1.92.110.6-1.9-1.61.00.50.53.30.60.40.4-0.10.6-0.3-0.91.82.61.9-1.51.7
Short access total infusions1.21.37.0-1.7-1.40.90.70.62.70.60.30.3-0.10.2-0.3-0.51.12.01.3-1.11.2
Short access day 1 locomotion1.41.56.1-1.9-1.61.20.50.62.50.70.50.2-0.10.8-0.3-0.31.01.91.5-0.71.7
Short access day 10 total locomotion1.01.13.9-1.6-1.41.00.40.62.00.80.60.4-0.31.10.2-0.61.11.61.2-0.41.5
Short access total locomotion1.21.34.8-1.6-1.30.90.20.32.20.60.30.2-0.10.9-0.2-0.31.21.91.5-0.81.9
One hour access (0.3 mA shock)6.67.715.4-3.9-3.93.42.93.23.03.33.02.9-2.83.32.5-3.11.41.60.01.4-0.0
Compulsive drug intake2.72.78.41.92.2-1.3-1.0-1.3-2.9-1.5-1.2-1.41.2-1.5-0.62.1-2.5-2.2-1.30.4-0.6
One hour access (shock baseline)7.28.416.7-3.9-4.13.22.83.23.53.33.03.0-2.93.22.3-3.72.32.00.41.2-0.3
Social response proportion0.50.51.21.00.8-1.1-0.9-0.9-0.6-0.8-0.9-0.70.8-0.8-0.70.50.2-0.10.3-0.60.1
Social responses0.40.51.61.20.6-0.5-0.4-0.5-1.3-0.5-0.4-0.20.2-0.7-0.10.5-1.0-1.1-0.70.1-0.9
Social time0.30.51.11.00.7-0.6-0.4-0.5-0.8-0.7-0.6-0.50.5-1.0-0.50.7-0.8-0.7-0.5-0.2-0.7
Soleus weight2.26.411.5-3.1-3.43.43.43.32.03.12.92.9-2.92.42.5-2.5-0.10.8-1.01.3-0.9
Bone: stiffness2.23.45.61.61.3-2.3-2.4-2.10.3-1.9-2.1-1.92.2-1.4-2.11.02.01.32.1-2.11.8
Tibialis anterior weight6.221.439.36.35.8-5.8-6.2-5.9-3.5-5.6-5.3-5.35.3-4.0-4.64.70.2-1.12.1-2.42.1
Time to tail flick, vehicle, before self-admin2.02.13.90.70.7-1.3-1.5-1.41.0-1.3-1.4-1.51.6-0.9-1.70.81.71.62.0-1.91.8
Time to tail flick, vehicle, after self-admin4.54.89.02.02.0-2.6-2.1-2.4-0.2-2.5-2.8-2.72.5-3.0-2.72.50.50.91.5-2.21.6
Time to tail flick, test, before self-admin0.80.83.0-0.6-0.70.2-0.2-0.21.5-0.1-0.4-0.70.8-0.2-1.00.60.61.51.4-1.01.7
Time to tail flick, test, after self-admin0.10.10.50.20.2-0.4-0.2-0.2-0.3-0.3-0.4-0.40.3-0.7-0.40.4-0.1-0.1-0.1-0.2-0.2
Delta time to tail flick, vehicle, before/after SA1.11.13.31.11.1-1.3-0.7-1.0-0.5-1.2-1.3-1.11.0-1.8-1.21.4-0.4-0.10.1-0.90.1
Delta time to tail flick, test, before/after SA1.11.04.10.91.0-0.5-0.1-0.1-2.0-0.10.10.3-0.5-0.00.7-0.2-0.9-1.9-1.51.1-1.7
Tibia length0.31.03.60.90.6-1.2-1.9-1.3-0.3-0.7-0.7-0.50.80.6-0.6-0.41.80.31.3-0.41.0
Ambulatory time before self-admin0.20.20.80.3-0.00.0-0.8-0.4-0.0-0.00.1-0.10.20.9-0.0-0.60.90.10.7-0.00.6
Ambulatory time after self-admin0.40.41.3-0.5-0.80.60.10.40.50.70.60.7-0.51.10.5-1.00.80.40.40.60.4
Bone: tissue strength0.10.10.3-0.3-0.30.30.20.30.00.40.40.4-0.40.50.4-0.50.1-0.2-0.20.2-0.5
Total heroin consumption2.83.36.42.42.5-2.4-2.1-2.2-1.9-2.3-1.9-2.11.8-2.0-1.71.8-0.5-1.20.0-0.7-0.2
Bone: trabecular number0.91.43.60.20.3-1.0-1.4-1.20.9-0.8-1.0-1.01.3-0.3-1.20.21.91.41.9-1.51.6
Bone: trabecular spacing0.70.93.20.00.00.81.10.8-0.90.50.70.6-0.80.00.90.0-1.8-1.3-1.61.1-1.4
Bone: trabecular thickness0.50.62.0-1.2-1.10.80.50.61.40.70.60.5-0.40.70.3-0.80.91.00.6-0.40.3
Bone: trabecular tissue density2.94.17.2-2.2-2.22.42.72.60.82.42.42.3-2.41.62.3-2.1-0.5-0.3-1.61.4-1.9
Water consumed over 24 hours0.60.72.81.31.1-0.7-0.6-0.6-1.7-0.6-0.4-0.30.2-0.30.10.6-1.0-1.4-0.80.7-0.7
Number of responses in last shaping day0.80.92.2-1.4-1.01.51.01.00.20.91.11.1-1.01.00.7-0.6-1.0-0.4-0.61.0-0.2