Hub : Traits

Soleus weight

Muscle

Tags: Physiology · Muscle

Project: lionikas_2014

14 loci · 28 genes with independent associations · 326 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr2	47538581	49244363	14	1	2.30e-09	2.46e-08	4.53e-01	Mocs2
2	chr2	111268894	114237500	6	4	6.00e-09	4.44e-10	1.00e+00	Ect2 Fndc3b Pld1 Slc2a2
3	chr2	115554411	119595215	50	1	3.67e-10	5.38e-10	1.00e+00	Gnb4
4	chr4	19000780	21703243	15	1	4.24e-12	2.33e-12	1.00e+00	LOC134486713
5	chr5	21900539	23299160	1	1	1.49e-07	9.78e-08	1.00e+00	Bpnt2
6	chr5	31288744	32685560	3	1	3.99e-08	1.94e-08	1.00e+00	Runx1t1l
7	chr5	37161074	38681225	4	1	3.56e-08	9.63e-09	4.56e-02	Cpne3
8	chr5	142962736	144036879	3	1	3.39e-09	1.35e-02	1.78e-01	Stk40
9	chr6	56652686	59547170	7	1	1.56e-08	7.42e-09	2.67e-46	Hdac9
10	chr7	7178376	11501489	60	1	1.16e-07	2.18e-07	2.59e-01	Scamp4
11	chr8	77975074	86331121	151	9	3.77e-14	3.77e-14	1.00e+00	Ccpg1 Dnaaf4 Gtf2a2 Leo1 LOC120094195 Pigb Rora Tmod3
12	chr8	111482194	113166330	2	1	1.01e-07	4.29e-08	1.00e+00	Amotl2
13	chr9	83390749	84777604	1	1	5.65e-15	4.06e-02	1.00e+00	Retreg2
14	chr20	5178240	6935766	9	4	1.61e-08	1.65e-08	1.00e+00	Ilrun LOC108349039 Snrpc Taf11

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	9.15	76	15	53.6	0.84	1.84e-113	Adam10 Ahr Aldh1a2 Ap3d1 Apc2 Aqp9 Arhgap45 Atosa Atp5f1d Bnip2 C7h19orf25 Cbarp Ccpg1 Cgnl1 Csnk1g2 Dnaaf4 Fam81a Fgf22 Gamt Gpx4 Grin3b Gtf2a2 Hdac9 Ice2 Izumo4 Khdc3 Lipc LOC103693140 LOC108351405 LOC120093775 LOC120094195 LOC120094203 LOC134479620 LOC134479811 LOC134480205 Midn Mier2 Mindy2 Mir628 Myo1e Myzap Ndufs7 Nedd4 Pcsk4 Pierce2 Pigb Plk5 Polr2m Polrmt Prtg Prtn3 Pwwp3a Pygo1 Rab27a Reep6 Retreg2 Rexo1 Rfx7 Rnf111 Rora Rpl37a-ps11 Rps15 Rsl24d1 Scamp4 Sf3a2 Sltm Spmap2 Tcf12 Tex9 Unc13c Wdr72 Zfp280d Zfp347 Zfp709l3 Zfp77 Znf431l4
BMI without tail	8182.37	6	1	3.6	0.98	8.62e-05	Amotl2 Itga1 Mocs2 Pelo Retreg2 Slco2a1
Body weight	4.56	39	1	3.6	1	0.00e+00	Adam10 Aldh1a2 Amotl2 Aqp9 Bnip2 Ccpg1 Cgnl1 Dnaaf4 Fam81a Gtf2a2 Ice2 Khdc3 Lipc LOC103693140 LOC120094195 LOC120094203 LOC134480205 Mindy2 Myo1e Myzap Nedd4 Pierce2 Pigb Polr2m Prtg Pygo1 Rab27a Retreg2 Rnf111 Rpl37a-ps11 Rsl24d1 Slco2a1 Sltm Stk40 Tcf12 Tex9 Wdr72 Wwp1 Zfp280d
Epididymis fat weight	2606.84	6	5	17.9	0.3	2.94e-01	Ahr Ilrun LOC108349039 Retreg2 Snrpc Taf11
Glucose	146.95	2	1	3.6	-0.73	2.65e-01	Retreg2 Stk40
Heart weight	3065.65	1	1	3.6	0	1.00e+00	Retreg2
Left kidney weight	55046.11	1	1	3.6	0	1.00e+00	Retreg2
Right kidney weight	40399.64	1	1	3.6	0	1.00e+00	Retreg2
Tail length	2070.46	7	1	3.6	0.39	1.67e-01	Amotl2 Ilrun LOC108349039 Retreg2 Slco2a1 Snrpc Taf11
Length with tail	130.54	5	4	14.3	0.61	3.66e-02	Ilrun LOC108349039 Retreg2 Snrpc Taf11
Length without tail	15747.97	3	1	3.6	0	1.00e+00	Adam10 Ilrun Retreg2
Liver weight, left	881.77	2	1	3.6	-0.38	6.17e-01	Retreg2 Stk40
Liver weight, right	14.53	5	1	3.6	0.6	3.87e-02	Ilrun LOC108349039 Retreg2 Snrpc Taf11
Parametrial fat weight	181.56	1	1	3.6	0	1.00e+00	Retreg2
Retroperitoneal fat weight	3938.69	1	1	3.6	0	1.00e+00	Retreg2
Intraocular pressure	10386.52	1	1	3.6	0	1.00e+00	Retreg2
Extensor digitorum longus weight	9.78	76	38	135.7	0.89	1.59e-155	Adam10 Ahr Aldh1a2 Ap3d1 Apc2 Aqp9 Arhgap45 Atp5f1d Bnip2 C7h19orf25 Cbarp Ccpg1 Cgnl1 Crppa Csnk1g2 Dnaaf4 Fam81a Fgf22 Gamt Gpx4 Grin3b Gtf2a2 Ice2 Izumo4 Khdc3 Lipc LOC103693140 LOC108351405 LOC120093775 LOC120094195 LOC120094203 LOC134479620 LOC134479811 LOC134480205 Midn Mier2 Mindy2 Mir628 Myo1e Myzap Ndufs7 Nedd4 Pcsk4 Pierce2 Pigb Plk5 Polr2m Polrmt Prtg Prtn3 Pwwp3a Pygo1 Rab27a Reep6 Retreg2 Rexo1 Rfx7 Rnf111 Rora Rpl37a-ps11 Rps15 Rsl24d1 Scamp4 Sf3a2 Sltm Spmap2 Stk40 Tcf12 Tex9 Unc13c Wdr72 Zfp280d Zfp347 Zfp709l3 Zfp77 Znf431l4
Tibialis anterior weight	15.17	53	40	142.9	0.88	2.56e-139	Adam10 Ahr Aldh1a2 Aqp9 Atosa Bnip2 Ccpg1 Cgnl1 Crppa Dnaaf4 Fam81a Gtf2a2 Hdac9 Ice2 Khdc3 Leo1 Lipc LOC100912347 LOC103693140 LOC120094195 LOC120094203 LOC134480205 Lysmd2 Mindy2 Mir628 Myo1e Myo5c Myzap Nedd4 Onecut1 Pierce2 Pigb Polr2m Prtg Pygo1 Rab27a Retreg2 Rfx7 Rnf111 Rora Rpl37a-ps11 Rsl24d1 Runx1t1l Scg3 Sltm Stk40 Tcf12 Tex9 Tmod2 Tmod3 Unc13c Wdr72 Zfp280d
Tibia length	767.35	1	1	3.6	0	1.00e+00	Retreg2
Number of licking bursts	67424.86	1	1	3.6	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	35509.41	1	1	3.6	0	1.00e+00	Retreg2
Times rat made contact with spout	71.66	1	1	3.6	0	1.00e+00	Retreg2
Mean time between licks in bursts	111630.35	1	1	3.6	0	1.00e+00	Retreg2
Mean num. licks in bursts	56750.08	1	1	3.6	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	29750.31	1	1	3.6	0	1.00e+00	Retreg2
Water consumed over 24 hours	34168.6	1	1	3.6	0	1.00e+00	Retreg2
Patch foraging indifference point 0 sec	39171.5	1	1	3.6	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	50128.13	1	1	3.6	0	1.00e+00	Retreg2
Indifference point function ln k	55646.82	1	1	3.6	0	1.00e+00	Retreg2
Indifference point function log k	55646.82	1	1	3.6	0	1.00e+00	Retreg2
Patch foraging total patch changes 0 sec	41947.04	1	1	3.6	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	2302.98	1	1	3.6	0	1.00e+00	Retreg2
Patch foraging total patch changes 18 sec	13491.93	2	1	3.6	0	1.00e+00	Retreg2 Stk40
Patch foraging total patch changes 24 sec	74801.17	1	1	3.6	0	1.00e+00	Retreg2
Patch foraging total patch changes 6 sec	7787.09	1	1	3.6	0	1.00e+00	Retreg2
Patch foraging time to switch 0 sec	66489.31	1	1	3.6	0	1.00e+00	Retreg2
Patch foraging water rate 0 sec	60426.37	1	1	3.6	0	1.00e+00	Retreg2
Patch foraging water rate 12 sec	70639.93	1	1	3.6	0	1.00e+00	Retreg2
Patch foraging water rate 18 sec	33728.57	1	1	3.6	0	1.00e+00	Retreg2
Patch foraging water rate 24 sec	1033.47	1	1	3.6	0	1.00e+00	Retreg2
Patch foraging water rate 6 sec	837.86	1	1	3.6	0	1.00e+00	Retreg2
Locomotor testing distance	27661.69	1	1	3.6	0	1.00e+00	Retreg2
Locomotor testing rearing	15857.92	2	1	3.6	-0.5	4.95e-01	Retreg2 Stk40
Light reinforcement 1	66311.75	1	1	3.6	0	1.00e+00	Retreg2
Light reinforcement 2	36738.3	1	1	3.6	0	1.00e+00	Retreg2
Reaction time number correct	10586.23	4	1	3.6	-0.55	2.61e-01	Cpne3 Retreg2 Runx1t1l Wwp1
Reaction time mean minus median	119950.29	1	1	3.6	0	1.00e+00	Retreg2
Reaction time mean minus median AUC	123988.85	1	1	3.6	0	1.00e+00	Retreg2
Reaction time num false alarms	15357.42	1	1	3.6	0	1.00e+00	Retreg2
Reaction time num false alarms AUC	17513.64	2	1	3.6	0	1.00e+00	Retreg2 Stk40
Reaction time trials correct on left	10586.23	4	1	3.6	-0.55	2.61e-01	Cpne3 Retreg2 Runx1t1l Wwp1
Reaction time trials on left	12183.89	3	1	3.6	-0.53	3.62e-01	Cpne3 Retreg2 Wwp1
Reaction time mean	29724.21	1	1	3.6	0	1.00e+00	Retreg2
Reaction time mean AUC	38768	1	1	3.6	0	1.00e+00	Retreg2
Median of all reaction times	7893.84	1	1	3.6	0	1.00e+00	Retreg2
Reaction time omissions	8364.84	1	1	3.6	0	1.00e+00	Retreg2
Reaction time false alarm rate	210.6	1	1	3.6	0	1.00e+00	Retreg2
Reaction time premature initiation rate	9733.76	1	1	3.6	0	1.00e+00	Retreg2
Reaction time premature initiations	53743.58	1	1	3.6	0	1.00e+00	Retreg2
Std. dev. reaction times	60865.09	1	1	3.6	0	1.00e+00	Retreg2
Reaction time trials completed	12183.89	3	1	3.6	-0.53	3.62e-01	Cpne3 Retreg2 Wwp1
Reaction time trials AUC	12433.59	3	1	3.6	-0.53	3.62e-01	Cpne3 Retreg2 Wwp1
Social response proportion	8777.03	1	1	3.6	0	1.00e+00	Retreg2
Social responses	638.87	2	1	3.6	0	1.00e+00	Retreg2 Zfp347
Social time	11650.06	1	1	3.6	0	1.00e+00	Retreg2
Conditioned locomotion	1400.08	1	1	3.6	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	19128.47	1	1	3.6	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	18571.31	1	1	3.6	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	3.6	0	1.00e+00	Retreg2
Saline control response	3160.68	1	1	3.6	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	14521.56	1	1	3.6	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	28713.86	1	1	3.6	0	1.00e+00	Retreg2
Condit. Reinf. active responses	2302.04	1	1	3.6	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	10889.7	1	1	3.6	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	3863.86	1	1	3.6	0	1.00e+00	Retreg2
Condit. Reinf. lever reinforcers received	469.54	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	2531.81	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	13282.18	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	39811.91	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. index score	12744.53	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	16150.81	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	5331.08	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	4012.39	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	34989.79	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	11800.43	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	588.37	2	1	3.6	0	1.00e+00	Itga1 Retreg2
Conditioned reinforcement - actives	100795.1	1	1	3.6	0	1.00e+00	Retreg2
Conditioned reinforcement - inactives	64866.71	1	1	3.6	0	1.00e+00	Retreg2
Conditioned locomotion	10334.01	1	1	3.6	0	1.00e+00	Retreg2
Intermittent access intake day 1-15 change	127876.18	1	1	3.6	0	1.00e+00	Retreg2
Intermittent access intake escalation	126068.82	1	1	3.6	0	1.00e+00	Retreg2
Intermittent access intake escalation 2	36175.43	1	1	3.6	0	1.00e+00	Retreg2
Intermitt. access day 1 inactive lever presses	180612.88	1	1	3.6	0	1.00e+00	Retreg2
Intermitt. access day 15 inactive lever presses	123608.2	1	1	3.6	0	1.00e+00	Retreg2
Intermitt. access escalation Index	93297.07	1	1	3.6	0	1.00e+00	Retreg2
Intermittent access day 1 total infusions	66115.79	1	1	3.6	0	1.00e+00	Retreg2
Intermittent access day 15 total infusions	48731.91	1	1	3.6	0	1.00e+00	Retreg2
Intermittent access terminal intake (last 3 days)	24800.59	1	1	3.6	0	1.00e+00	Retreg2
Intermittent access total infusions	181.04	1	1	3.6	0	1.00e+00	Retreg2
Intermittent access day 1 locomotion	34964.22	1	1	3.6	0	1.00e+00	Retreg2
Intermittent access day 15 total locomotion	85548.8	1	1	3.6	0	1.00e+00	Retreg2
Intermittent access total locomotion	116.36	1	1	3.6	0	1.00e+00	Retreg2
Intermittent access standard deviation	113962.95	1	1	3.6	0	1.00e+00	Retreg2
Cocaine induced anxiety	69097.7	1	1	3.6	0	1.00e+00	Retreg2
Post-drug Anxiety	4753.56	1	1	3.6	0	1.00e+00	Retreg2
Baseline Anxiety	33506.24	1	1	3.6	0	1.00e+00	Retreg2
Lifetime Intake	1655.49	1	1	3.6	0	1.00e+00	Retreg2
Incentive Sensitization - Responses	71347.91	1	1	3.6	0	1.00e+00	Retreg2
Incentive Sensitization - Breakpoint	55273.76	1	1	3.6	0	1.00e+00	Retreg2
Progressive ratio test 1 active lever presses	31979.35	1	1	3.6	0	1.00e+00	Retreg2
Progressive ratio test 1 breakpoint	30292.17	1	1	3.6	0	1.00e+00	Retreg2
Progressive ratio test 1 inactive lever presses	62205.59	1	1	3.6	0	1.00e+00	Retreg2
Progressive ratio test 2 active lever presses	15263.76	1	1	3.6	0	1.00e+00	Retreg2
Progressive ratio test 2 breakpoint	8542.35	1	1	3.6	0	1.00e+00	Retreg2
Progressive ratio test 2 inactive lever presses	72504.33	1	1	3.6	0	1.00e+00	Retreg2
Total sessions with >9 infusions	1959.63	1	1	3.6	0	1.00e+00	Retreg2
Short access day 1 total inactive lever presses	39407.55	1	1	3.6	0	1.00e+00	Retreg2
Short access day 10 total inactive lever presses	138842.31	1	1	3.6	0	1.00e+00	Retreg2
Short access day 1 total infusions	38385.19	1	1	3.6	0	1.00e+00	Retreg2
Short access day 10 total infusions	22696.46	1	1	3.6	0	1.00e+00	Retreg2
Short access total infusions	8778.92	1	1	3.6	0	1.00e+00	Retreg2
Short access day 1 locomotion	24803.24	1	1	3.6	0	1.00e+00	Retreg2
Short access day 10 total locomotion	88176.71	1	1	3.6	0	1.00e+00	Retreg2
Short access total locomotion	18677.85	1	1	3.6	0	1.00e+00	Retreg2
Compulsive drug intake	18679.82	1	1	3.6	0	1.00e+00	Retreg2
One hour access (0.3 mA shock)	2329.1	1	1	3.6	0	1.00e+00	Retreg2
One hour access (shock baseline)	54988.81	1	1	3.6	0	1.00e+00	Retreg2
Number of responses in last shaping day	13618.48	1	1	3.6	0	1.00e+00	Retreg2
Context. condit. distance diff. score	212.47	1	1	3.6	0	1.00e+00	Retreg2
Locomotion velocity, session 1	3523.61	1	1	3.6	0	1.00e+00	Retreg2
Locomotion distance, session 1	1024.77	1	1	3.6	0	1.00e+00	Retreg2
Locomotion velocity, session 2	2158.08	1	1	3.6	0	1.00e+00	Retreg2
Locomotion distance, session 2	508.11	1	1	3.6	0	1.00e+00	Retreg2
Locomotion velocity, session 3	507.49	1	1	3.6	0	1.00e+00	Retreg2
Locomotion distance, session 3	4009.46	1	1	3.6	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	1361.96	1	1	3.6	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	2872.44	1	1	3.6	0	1.00e+00	Retreg2
Locomotion velocity, session 7	292.79	1	1	3.6	0	1.00e+00	Retreg2
Locomotion distance, session 7	856.72	1	1	3.6	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 7	2509.72	1	1	3.6	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	2115.93	1	1	3.6	0	1.00e+00	Retreg2
Locomotion velocity, session 8	409.23	1	1	3.6	0	1.00e+00	Retreg2
Locomotion distance, session 8	147.88	1	1	3.6	0	1.00e+00	Retreg2
Degree of sensitization distance	3670.85	1	1	3.6	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	2042.98	1	1	3.6	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	957.65	1	1	3.6	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	242.03	1	1	3.6	0	1.00e+00	Retreg2
Condit. Reinf. active responses	2765.7	1	1	3.6	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	4681.39	1	1	3.6	0	1.00e+00	Retreg2
Incentive salience index mean	901.02	2	2	7.1	0.61	3.93e-01	Retreg2 Stk40
Condit. Reinf. lever presses	1332.63	2	1	3.6	0.57	4.28e-01	Retreg2 Stk40
Time in familiar zone, hab. session 1	11168.49	1	1	3.6	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	9232.79	1	1	3.6	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	429.72	1	1	3.6	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	394.1	1	1	3.6	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	266.96	1	1	3.6	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	5880.03	1	1	3.6	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	6311.49	1	1	3.6	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	63.93	1	1	3.6	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 2	22.17	1	1	3.6	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 2	31.27	1	1	3.6	0	1.00e+00	Retreg2
Novel to familiar place preference ratio	15339.58	1	1	3.6	0	1.00e+00	Retreg2
Novelty place preference	4986.29	3	1	3.6	0	1.00e+00	LOC120100791 Retreg2 Tnik
Time in novel zone, NPP test	1540.65	5	1	3.6	0.57	1.85e-01	Egfem1 LOC120100791 Pld1 Retreg2 Tnik
Total zone transitions, NPP test	1935.62	1	1	3.6	0	1.00e+00	Retreg2
Total locomotion distance, NPP test	1687.31	1	1	3.6	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	953.07	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	491.79	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	1037.76	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. index score	384.43	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	404.63	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	677.08	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	491.61	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	123.55	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	418.89	1	1	3.6	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	583.93	1	1	3.6	0	1.00e+00	Retreg2
Bone: apparent density	1827.25	2	1	3.6	0	1.00e+00	Retreg2 Stk40
Bone surface	1557.3	2	1	3.6	0.55	4.51e-01	Retreg2 Stk40
Bone volume	2171.98	2	2	7.1	0.56	4.38e-01	Retreg2 Stk40
Bone: connectivity density	1667.52	1	1	3.6	0	1.00e+00	Retreg2
Bone: cortical apparent density	12020.36	1	1	3.6	0	1.00e+00	Retreg2
Bone: cortical area	4581.96	1	1	3.6	0	1.00e+00	Retreg2
Bone: cortical porosity	432.96	1	1	3.6	0	1.00e+00	Retreg2
Bone: cortical porosity	1113.18	1	1	3.6	0	1.00e+00	Retreg2
Bone: cortical thickness	374.52	1	1	3.6	0	1.00e+00	Retreg2
Bone: cortical thickness	2918.77	1	1	3.6	0	1.00e+00	Retreg2
Bone: cortical tissue density	13002.58	1	1	3.6	0	1.00e+00	Retreg2
Bone: elastic displacement	7604.03	1	1	3.6	0	1.00e+00	Retreg2
Bone: elastic work	361.86	1	1	3.6	0	1.00e+00	Retreg2
Bone: endosteal estimation	1492.77	3	1	3.6	0.77	7.58e-02	Ilrun LOC108349039 Retreg2
Bone: endosteal perimeter	11863.6	1	1	3.6	0	1.00e+00	Retreg2
Bone: final force	1600.36	1	1	3.6	0	1.00e+00	Retreg2
Bone: final moment	219.15	1	1	3.6	0	1.00e+00	Retreg2
Bone: marrow area	1578.77	3	1	3.6	0.76	7.66e-02	Ilrun LOC108349039 Retreg2
Bone: maximum diameter	3039.32	2	1	3.6	0	1.00e+00	Retreg2 Runx1t1l
Bone: maximum force	8697.09	1	1	3.6	0	1.00e+00	Retreg2
Bone: maximum moment	5989.29	1	1	3.6	0	1.00e+00	Retreg2
Bone: minimum diameter	4100.86	1	1	3.6	0	1.00e+00	Retreg2
Bone: periosteal estimation	9791.57	1	1	3.6	0	1.00e+00	Retreg2
Bone: periosteal perimeter	11400.25	1	1	3.6	0	1.00e+00	Retreg2
Bone: post-yield work	13672.98	1	1	3.6	0	1.00e+00	Retreg2
Bone: stiffness	9032.86	1	1	3.6	0	1.00e+00	Retreg2
Bone: tissue strength	2995.95	1	1	3.6	0	1.00e+00	Retreg2
Bone: trabecular number	10739.78	1	1	3.6	0	1.00e+00	Retreg2
Bone: trabecular spacing	7952.12	1	1	3.6	0	1.00e+00	Retreg2
Bone: trabecular thickness	8476.26	1	1	3.6	0	1.00e+00	Retreg2
Bone: trabecular tissue density	1466.11	5	1	3.6	0.34	3.44e-01	Ccpg1 Nedd4 Pigb Retreg2 Tex9
Breakpoint value in progressive ratio session	37605.61	1	1	3.6	0	1.00e+00	Retreg2
Distance traveled before self-admin	50534.09	1	1	3.6	0	1.00e+00	Retreg2
Distance traveled after self-admin	32464.08	1	1	3.6	0	1.00e+00	Retreg2
Delta time in closed arm before/after self-admin	244.69	1	1	3.6	0	1.00e+00	Retreg2
Delta time in open arm before/after self-admin	15131.21	1	1	3.6	0	1.00e+00	Retreg2
Diff in mean of infusions in LGA sessions	36650	1	1	3.6	0	1.00e+00	Retreg2
Extinction: sum of active levers before priming	28373.8	1	1	3.6	0	1.00e+00	Retreg2
Active lever presses in extinction session 6	738.98	1	1	3.6	0	1.00e+00	Retreg2
Delta distance traveled before/after self-admin	2940.47	1	1	3.6	0	1.00e+00	Retreg2
Delta ambulatory time before/after self-admin	30849.75	1	1	3.6	0	1.00e+00	Retreg2
Time in closed arm before self-admin	26866.11	1	1	3.6	0	1.00e+00	Retreg2
Time in closed arm after self-admin	4591.18	1	1	3.6	0	1.00e+00	Retreg2
Time in open arm before self-admin	8746.25	1	1	3.6	0	1.00e+00	Retreg2
Time in open arm after self-admin	477.73	1	1	3.6	0	1.00e+00	Retreg2
Sum of active levers in priming session hrs 5-6	978.69	1	1	3.6	0	1.00e+00	Retreg2
Time to tail flick, vehicle, before self-admin	13364.89	1	1	3.6	0	1.00e+00	Retreg2
Time to tail flick, vehicle, after self-admin	42142.71	1	1	3.6	0	1.00e+00	Retreg2
Time to tail flick, test, before self-admin	8139.55	1	1	3.6	0	1.00e+00	Retreg2
Time to tail flick, test, after self-admin	1399.18	1	1	3.6	0	1.00e+00	Retreg2
Delta time to tail flick, vehicle, before/after SA	9805.78	1	1	3.6	0	1.00e+00	Retreg2
Delta time to tail flick, test, before/after SA	15684.59	1	1	3.6	0	1.00e+00	Retreg2
Ambulatory time before self-admin	78874.38	1	1	3.6	0	1.00e+00	Retreg2
Ambulatory time after self-admin	26614.91	1	1	3.6	0	1.00e+00	Retreg2
Total heroin consumption	240.55	1	1	3.6	0	1.00e+00	Retreg2
Area under the delay curve	24791.27	1	1	3.6	0	1.00e+00	Retreg2
Delay disc. indifference point, 0s delay	2159.25	1	1	3.6	0	1.00e+00	Retreg2
Delay disc. indifference point, 16s delay	21959.9	1	1	3.6	0	1.00e+00	Retreg2
Delay disc. indifference point, 2s delay	155.27	1	1	3.6	0	1.00e+00	Retreg2
Delay disc. indifference point, 24s delay	32437.06	1	1	3.6	0	1.00e+00	Retreg2
Delay disc. indifference point, 4s delay	616.19	1	1	3.6	0	1.00e+00	Retreg2
Delay disc. indifference point, 8s delay	33362.4	1	1	3.6	0	1.00e+00	Retreg2
Delay discount exponential model param	16922.54	1	1	3.6	0	1.00e+00	Retreg2
Delay discount hyperbolic model param	12277.65	1	1	3.6	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	61202.36	1	1	3.6	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	5669.94	1	1	3.6	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 1	13009.3	1	1	3.6	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 1	10785.17	1	1	3.6	0	1.00e+00	Retreg2
Total resting periods, locomotor time 1	2793.59	1	1	3.6	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	22349.64	1	1	3.6	0	1.00e+00	Retreg2
Distance moved, locomotor task time 1	68821.85	1	1	3.6	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 1	142354.07	1	1	3.6	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	71159.6	1	1	3.6	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 2	82029.05	1	1	3.6	0	1.00e+00	Retreg2
Total resting periods, locomotor time 2	99042.67	1	1	3.6	0	1.00e+00	Retreg2
Rest time, locomotor task time 2	25503.09	1	1	3.6	0	1.00e+00	Retreg2
Distance moved, locomotor task time 2	8477.87	1	1	3.6	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 2	53555.35	1	1	3.6	0	1.00e+00	Retreg2
Weight adjusted by age	70782.25	1	1	3.6	0	1.00e+00	Retreg2
Seeking ratio, delayed vs. immediate footshock	13445.31	1	1	3.6	0	1.00e+00	Retreg2
Locomotion in novel chamber	3903.37	1	1	3.6	0	1.00e+00	Retreg2
Locomotion in novel chamber post-restriction	65422.89	1	1	3.6	0	1.00e+00	Retreg2
Progressive ratio	67888.93	1	1	3.6	0	1.00e+00	Retreg2
Food seeking constrained by brief footshock	1875.34	1	1	3.6	0	1.00e+00	Retreg2
Seeking ratio, punishment vs. effort	41283.25	1	1	3.6	0	1.00e+00	Retreg2
Run reversals in cocaine runway, females	9406.04	1	1	3.6	0	1.00e+00	Retreg2
Run reversals in cocaine runway, males	7664.74	1	1	3.6	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway	16290.75	1	1	3.6	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, F	7166.92	1	1	3.6	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	1716.51	1	1	3.6	0	1.00e+00	Retreg2
Co content in liver	1133.25	1	1	3.6	0	1.00e+00	Retreg2
Cu content in liver	39.92	1	1	3.6	0	1.00e+00	Retreg2
Fe content in liver	1344.53	1	1	3.6	0	1.00e+00	Retreg2
K content in liver	1519.62	1	1	3.6	0	1.00e+00	Retreg2
Mg content in liver	6026.97	1	1	3.6	0	1.00e+00	Retreg2
Mn content in liver	1009.39	1	1	3.6	0	1.00e+00	Retreg2
Na content in liver	4018.36	1	1	3.6	0	1.00e+00	Retreg2
Rb content in liver	35.67	2	1	3.6	-0.96	3.74e-02	Retreg2 Stk40
Sr content in liver	104.71	1	1	3.6	0	1.00e+00	Stk40
Zn content in liver	3745.55	1	1	3.6	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	10	0.3	2.78
Adipose	alternative TSS	15	0.4	2.89
Adipose	gene expression	24	0.2	2.89
Adipose	isoform ratio	16	0.3	2.87
Adipose	intron excision ratio	5	0.2	3.47
Adipose	mRNA stability	18	0.4	2.96
BLA	alternative polyA	9	0.4	3
BLA	alternative TSS	5	0.3	2.92
BLA	gene expression	18	0.3	3.01
BLA	isoform ratio	15	0.5	3.11
BLA	intron excision ratio	5	0.2	3.05
BLA	mRNA stability	12	0.5	3.09
Brain	alternative polyA	14	0.4	2.98
Brain	alternative TSS	10	0.2	3.06
Brain	gene expression	31	0.3	2.93
Brain	isoform ratio	17	0.3	3.02
Brain	intron excision ratio	13	0.2	3.17
Brain	mRNA stability	14	0.3	2.95
Eye	alternative polyA	0	0	3.29
Eye	alternative TSS	3	0.7	3.22
Eye	gene expression	3	0.2	3.15
Eye	isoform ratio	1	0.2	3.03
Eye	intron excision ratio	3	0.3	3.27
Eye	mRNA stability	0	0	2.81
IC	alternative polyA	6	0.3	2.83
IC	alternative TSS	4	0.2	3.09
IC	gene expression	17	0.3	3.05
IC	isoform ratio	7	0.3	2.89
IC	intron excision ratio	6	0.2	3.01
IC	mRNA stability	6	0.4	2.98
IL	alternative polyA	3	0.3	2.99
IL	alternative TSS	0	0	2.68
IL	gene expression	11	0.3	2.99
IL	isoform ratio	5	0.4	3.15
IL	intron excision ratio	0	0	2.73
IL	mRNA stability	5	0.4	3.06
LHb	alternative polyA	4	0.4	2.9
LHb	alternative TSS	0	0	2.59
LHb	gene expression	11	0.3	3.01
LHb	isoform ratio	3	0.2	2.66
LHb	intron excision ratio	4	0.3	2.95
LHb	mRNA stability	3	0.2	3.02
Liver	alternative polyA	10	0.4	2.76
Liver	alternative TSS	11	0.4	2.88
Liver	gene expression	21	0.3	2.92
Liver	isoform ratio	11	0.3	2.92
Liver	intron excision ratio	4	0.1	3.03
Liver	mRNA stability	9	0.3	2.97
NAcc	alternative polyA	9	0.3	2.9
NAcc	alternative TSS	6	0.2	2.97
NAcc	gene expression	34	0.3	3.04
NAcc	isoform ratio	20	0.4	3.08
NAcc	intron excision ratio	19	0.3	2.92
NAcc	mRNA stability	13	0.4	3.09
OFC	alternative polyA	1	0.1	2.92
OFC	alternative TSS	2	0.3	3.2
OFC	gene expression	8	0.2	2.98
OFC	isoform ratio	6	0.4	2.85
OFC	intron excision ratio	1	0.1	3.14
OFC	mRNA stability	6	0.5	3.08
PL	alternative polyA	13	0.4	2.94
PL	alternative TSS	10	0.3	3.04
PL	gene expression	22	0.2	2.93
PL	isoform ratio	20	0.4	3.06
PL	intron excision ratio	10	0.2	2.83
PL	mRNA stability	15	0.4	3.08
pVTA	alternative polyA	7	0.3	2.98
pVTA	alternative TSS	5	0.2	3.1
pVTA	gene expression	25	0.3	3.04
pVTA	isoform ratio	12	0.3	2.99
pVTA	intron excision ratio	9	0.2	2.84
pVTA	mRNA stability	7	0.3	3.08
RMTg	alternative polyA	4	0.7	3.23
RMTg	alternative TSS	1	0.2	2.71
RMTg	gene expression	11	0.6	3.05
RMTg	isoform ratio	4	0.5	3.04
RMTg	intron excision ratio	0	0	3.13
RMTg	mRNA stability	4	0.7	3.02