Hub : Traits : Tibialis anterior weight : ← : →

chr10:59,271,871-62,026,829

Trait: Tibialis anterior weight

Best TWAS P = 2.73e-10 · Best GWAS P= 3.04e-10 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Slc43a2	alternative polyA	NM_001105812.1	0.03	1066	0.01	1.3e-02	-6.16	7.37e-10	0.6	FALSE
Adipose	Slc43a2	alternative polyA	NM_001105812.1	0.18	1066	0.07	2.9e-08	-5.42	6.03e-08	0.76	FALSE
Adipose	Slc43a2	alternative polyA	XM_039085518.2	0.18	1066	0.07	3.0e-08	5.37	7.68e-08	0.75	FALSE
Adipose	Rpa1	alternative TSS	NM_001394069.1	0.06	832	0.03	9.6e-05	5.3	1.13e-07	0.71	FALSE
Adipose	Rpa1	isoform ratio	NM_001394069.1	0.07	832	0.04	8.7e-05	5.38	7.46e-08	0.73	FALSE
Adipose	Slc43a2	isoform ratio	NM_001105812.1	0.06	1066	0.03	6.0e-04	-6.22	5.05e-10	0.75	FALSE
Adipose	Smg6	isoform ratio	XM_063268674.1	0.05	828	0.03	6.3e-04	5.6	2.11e-08	0.75	FALSE
Adipose	Myo1c	intron excision ratio	chr10_60997757_61003351	0.08	1	0.03	1.9e-04	-6.22	5.03e-10	0.3	FALSE
Adipose	Ccdc92b	mRNA stability	Ccdc92b	0.07	1192	0.03	4.4e-04	5.62	1.88e-08	0.84	FALSE
Adipose	Crk	mRNA stability	Crk	0.17	21	0.14	3.8e-15	5.86	4.49e-09	0.8	FALSE
Adipose	Sgsm2	mRNA stability	Sgsm2	0.02	73	0	1.5e-01	5.5	3.82e-08	0.41	FALSE
BLA	Rap1gap2	alternative TSS	NM_001401654.1	0.09	1	0.06	6.1e-04	5.61	2.00e-08	0.06	FALSE
BLA	Rph3al	alternative TSS	XM_063268369.1	0.15	1224	0.02	4.5e-02	5.57	2.52e-08	0.58	FALSE
BLA	Rph3al	alternative TSS	XM_063268369.1	0.14	1224	0.02	2.3e-02	5.37	7.95e-08	0.55	FALSE
BLA	Crk	gene expression	Crk	0.17	109	0.12	8.4e-07	-6.11	9.87e-10	0.81	FALSE
BLA	Inpp5k	gene expression	Inpp5k	0.22	1	0.17	3.8e-09	-6.23	4.80e-10	0.81	FALSE
BLA	Rap1gap2	gene expression	Rap1gap2	0.25	25	0.19	1.4e-10	5.63	1.80e-08	0.77	FALSE
BLA	Wdr81	gene expression	Wdr81	0.06	1015	0.04	5.0e-03	-5.22	1.81e-07	0.27	FALSE
BLA	Rap1gap2	isoform ratio	NM_001401654.1	0.06	1	0.04	5.2e-03	5.61	2.00e-08	0.04	FALSE
BLA	Smyd4	intron excision ratio	chr10_60698680_60699761	0.08	22	0.05	9.6e-04	-6.22	4.82e-10	0.75	FALSE
BLA	Crk	mRNA stability	Crk	0.32	1213	0.28	1.9e-15	6.13	8.75e-10	0.82	FALSE
BLA	Doc2b	mRNA stability	Doc2b	0.24	1	0.12	5.7e-07	5.71	1.10e-08	0.12	FALSE
BLA	Mettl16	mRNA stability	Mettl16	0.06	742	0.04	4.3e-03	5.28	1.29e-07	0.54	FALSE
BLA	Rph3al	mRNA stability	Rph3al	0.3	1	0.12	4.3e-07	-5.22	1.75e-07	0.03	FALSE
Brain	Rph3al	alternative polyA	XM_039085148.2	0.29	1	0.1	1.6e-09	-5.21	1.84e-07	0.03	FALSE
Brain	Rph3al	alternative polyA	XM_063268371.1	0.26	1	0.09	8.0e-09	5.21	1.84e-07	0.03	FALSE
Brain	Slc43a2	alternative polyA	XM_063268681.1	0.06	37	0.04	8.8e-05	5.57	2.53e-08	0.66	FALSE
Brain	Myo1c	alternative TSS	XM_039086809.1	0.05	48	0.03	2.0e-03	-5.34	9.34e-08	0.58	TRUE
Brain	Crk	gene expression	Crk	0.33	14	0.26	2.8e-24	6.22	4.89e-10	0.82	FALSE
Brain	Doc2b	gene expression	Doc2b	0.74	98	0.54	6.4e-59	-5.77	8.01e-09	0.83	FALSE
Brain	Pafah1b1	gene expression	Pafah1b1	0.03	1	0.02	3.2e-03	6.07	1.26e-09	0.1	FALSE
Brain	Rap1gap2	gene expression	Rap1gap2	0.38	6	0.54	2.6e-59	5.93	3.07e-09	0.85	FALSE
Brain	Rph3al	gene expression	Rph3al	0.49	1225	0.31	1.6e-29	5.36	8.21e-08	0.06	FALSE
Brain	Rtn4rl1	gene expression	Rtn4rl1	0.3	1	0.18	1.4e-16	-6.22	4.89e-10	0.82	FALSE
Brain	Slc43a2	gene expression	Slc43a2	0.19	1066	0.13	3.0e-12	5.79	6.98e-09	0.77	FALSE
Brain	Smyd4	isoform ratio	NM_001105810.1	0.06	832	0.05	3.6e-05	-5.42	6.00e-08	0.62	FALSE
Brain	Smyd4	isoform ratio	XM_063268677.1	0.07	832	0.06	1.2e-06	5.59	2.32e-08	0.73	FALSE
Brain	Doc2b	intron excision ratio	chr10_61131293_61135052	0.15	23	0.09	2.5e-08	-5.93	2.99e-09	0.81	FALSE
Brain	Smyd4	intron excision ratio	chr10_60698680_60699761	0.12	215	0.12	7.2e-11	5.92	3.21e-09	0.76	FALSE
Brain	Smyd4	intron excision ratio	chr10_60699535_60699761	0.06	87	0.05	9.3e-06	-5.65	1.56e-08	0.55	FALSE
Brain	Ccdc92b	mRNA stability	Ccdc92b	0.05	1	0.04	7.8e-05	-5.45	4.99e-08	0.08	TRUE
Brain	Crk	mRNA stability	Crk	0.36	14	0.27	3.8e-25	6.21	5.34e-10	0.82	FALSE
Brain	Doc2b	mRNA stability	Doc2b	0.54	117	0.38	8.4e-38	6.04	1.53e-09	0.84	FALSE
Brain	LOC102549294	mRNA stability	LOC102549294	0.03	2	0.02	1.0e-02	5.21	1.85e-07	0.45	TRUE
Brain	Serpinf1	mRNA stability	Serpinf1	0.04	944	0.03	1.8e-03	-5.8	6.75e-09	0.69	FALSE
Brain	Slc43a2	mRNA stability	Slc43a2	0.08	1	0.08	1.1e-07	6.12	9.12e-10	0.68	FALSE
Brain	Smyd4	mRNA stability	Smyd4	0.05	63	0.04	5.0e-05	5.88	4.05e-09	0.1	FALSE
Eye	Serpinf1	gene expression	Serpinf1	0.31	1	0.08	2.6e-02	5.98	2.28e-09	0.06	FALSE
IC	Rap1gap2	alternative TSS	NM_001401654.1	0.08	1190	0.03	1.4e-02	-5.83	5.50e-09	0.63	FALSE
IC	Doc2b	gene expression	Doc2b	0.4	173	0.26	3.0e-11	-6.22	5.00e-10	0.83	FALSE
IC	Mnt	gene expression	Mnt	0.08	1	0.06	2.5e-03	5.87	4.32e-09	0.05	FALSE
IC	Rap1gap2	gene expression	Rap1gap2	0.59	90	0.56	7.9e-28	-5.81	6.22e-09	0.61	FALSE
IC	Rtn4rl1	gene expression	Rtn4rl1	0.42	1	0.37	3.2e-16	-5.87	4.42e-09	0.35	FALSE
IC	Rph3al	isoform ratio	XM_008767941.4	0.18	1225	0.08	3.9e-04	5.48	4.32e-08	0.72	FALSE
IC	Rap1gap2	intron excision ratio	chr10_59855162_59892814	0.15	1190	0.12	7.7e-06	5.82	5.96e-09	0.75	FALSE
IC	Smyd4	intron excision ratio	chr10_60698680_60699761	0.12	832	0.1	4.7e-05	-5.59	2.31e-08	0.61	FALSE
IC	Smyd4	intron excision ratio	chr10_60699535_60699761	0.07	832	0.05	4.3e-03	5.42	5.87e-08	0.37	FALSE
IC	Crk	mRNA stability	Crk	0.39	1	0.3	3.2e-13	-6.25	4.23e-10	0.83	FALSE
IL	Crk	gene expression	Crk	0.2	304	0.03	6.7e-02	-5.88	4.17e-09	0.44	FALSE
IL	Doc2b	gene expression	Doc2b	0.25	14	0.08	5.2e-03	6.04	1.52e-09	0.55	FALSE
IL	Rap1gap2	gene expression	Rap1gap2	0.81	285	0.38	5.5e-10	-6	2.03e-09	0.86	FALSE
IL	Rtn4rl1	gene expression	Rtn4rl1	0.3	63	0.22	5.7e-06	-5.86	4.71e-09	0.69	FALSE
IL	Crk	mRNA stability	Crk	0.2	1	0.11	1.5e-03	-6.09	1.16e-09	0.06	FALSE
LHb	Crk	gene expression	Crk	0.36	1213	0.27	3.5e-07	6.04	1.57e-09	0.79	FALSE
Liver	Slc43a2	alternative polyA	NM_001105812.1	0.04	1	0.03	8.5e-04	5.57	2.54e-08	0.03	FALSE
Liver	Slc43a2	alternative polyA	XM_039085518.2	0.05	1	0.04	9.0e-05	-6.03	1.61e-09	0.12	FALSE
Liver	Slc43a2	alternative polyA	NM_001105812.1	0.04	1	0.03	4.4e-04	6.03	1.61e-09	0.06	FALSE
Liver	Slc43a2	alternative polyA	XM_039085518.2	0.04	1	0.03	3.5e-04	-6.03	1.61e-09	0.07	FALSE
Liver	Sgsm2	alternative TSS	XM_006246740.4	0.06	6	0.02	9.0e-04	-5.5	3.90e-08	0.64	FALSE
Liver	Sgsm2	alternative TSS	XM_006246740.4	0.04	1	0.03	7.5e-04	5.5	3.90e-08	0.03	FALSE
Liver	Rpa1	gene expression	Rpa1	0.13	1	0.09	3.7e-10	-6.22	4.86e-10	0.8	FALSE
Liver	Serpinf1	gene expression	Serpinf1	0.03	1	0.01	8.0e-03	-5.54	2.96e-08	0.03	FALSE
Liver	Slc43a2	isoform ratio	NM_001105812.1	0.04	1	0.03	8.4e-04	6.03	1.61e-09	0.05	FALSE
Liver	Slc43a2	isoform ratio	XM_063268680.1	0.03	1066	0.02	6.2e-03	5.74	9.35e-09	0.59	FALSE
Liver	Smyd4	isoform ratio	NM_001105810.1	0.04	832	0.03	4.0e-04	-5.46	4.68e-08	0.53	FALSE
Liver	Smyd4	isoform ratio	XM_063268677.1	0.05	832	0.04	2.6e-05	5.22	1.75e-07	0.44	FALSE
Liver	Slc43a2	intron excision ratio	chr10_60911888_60913024	0.03	1066	0.01	7.6e-03	5.78	7.59e-09	0.43	FALSE
Liver	Smyd4	intron excision ratio	chr10_60698680_60699312	0.02	832	0.01	1.3e-02	5.74	9.57e-09	0.34	FALSE
Liver	Smyd4	intron excision ratio	chr10_60698680_60699761	0.02	1	0.01	1.2e-02	6.03	1.67e-09	0.03	FALSE
Liver	Crk	mRNA stability	Crk	0.09	1	0.04	6.1e-05	-6.09	1.16e-09	0.41	FALSE
NAcc	Ywhae	alternative TSS	XM_039085798.2	0.03	1291	0.01	3.4e-02	5.57	2.57e-08	0.65	FALSE
NAcc	Crk	gene expression	Crk	0.51	1213	0.23	7.7e-35	5.72	1.07e-08	0.46	FALSE
NAcc	Doc2b	gene expression	Doc2b	0.43	60	0.42	2.1e-68	6.25	4.10e-10	0.85	FALSE
NAcc	Mnt	gene expression	Mnt	0.13	1	0.08	4.7e-12	6.03	1.67e-09	0.75	FALSE
NAcc	Rap1gap2	gene expression	Rap1gap2	0.07	1	0.06	8.2e-10	-5.47	4.40e-08	0.34	FALSE
NAcc	Slc43a2	gene expression	Slc43a2	0.19	102	0.24	1.1e-35	-5.6	2.21e-08	0	FALSE
NAcc	LOC102549294	isoform ratio	XR_010055681.1	0.03	1293	0.01	3.3e-02	-5.78	7.57e-09	0.73	FALSE
NAcc	Mnt	isoform ratio	NM_001105807.2	0.02	1	0.01	4.4e-03	-5.97	2.44e-09	0.04	FALSE
NAcc	Smyd4	isoform ratio	XM_063268677.1	0.04	44	0.04	1.5e-06	-5.59	2.31e-08	0.4	TRUE
NAcc	LOC102549294	intron excision ratio	chr10_61181793_61202406	0.04	1293	0.02	1.4e-03	-5.97	2.37e-09	0.81	FALSE
NAcc	LOC134480823	intron excision ratio	chr10_61181793_61202406	0.03	1318	0.02	1.4e-03	-5.98	2.18e-09	0.8	FALSE
NAcc	Mnt	intron excision ratio	chr10_60207564_60209659	0.02	800	0.01	2.1e-03	-6.1	1.09e-09	0.78	FALSE
NAcc	Smyd4	intron excision ratio	chr10_60698680_60699761	0.11	832	0.12	2.5e-17	-5.25	1.55e-07	0.57	FALSE
NAcc	Ccdc92b	mRNA stability	Ccdc92b	0.03	1	0.03	2.0e-05	-5.83	5.71e-09	0.51	FALSE
NAcc	Crk	mRNA stability	Crk	0.23	1213	0.22	9.4e-33	6.01	1.87e-09	0.82	FALSE
NAcc	Doc2b	mRNA stability	Doc2b	0.05	30	0.03	4.0e-05	5.61	1.98e-08	0.81	TRUE
OFC	LOC102549294	alternative TSS	XR_010055680.1	0.24	11	0.13	5.9e-04	-5.49	4.03e-08	0.5	FALSE
OFC	LOC102549294	alternative TSS	XR_010055681.1	0.23	1	0.14	2.8e-04	-5.54	3.02e-08	0.05	FALSE
OFC	Crk	gene expression	Crk	0.29	1213	0.24	2.2e-06	6.01	1.86e-09	0.79	FALSE
OFC	Doc2b	gene expression	Doc2b	0.41	1	0.08	6.1e-03	-6.12	9.19e-10	0.06	FALSE
OFC	Rph3al	gene expression	Rph3al	0.38	1225	0.27	3.2e-07	5.42	5.95e-08	0.82	FALSE
OFC	Rtn4rl1	gene expression	Rtn4rl1	0.13	770	0.05	2.5e-02	5.91	3.38e-09	0.43	FALSE
OFC	Serpinf1	gene expression	Serpinf1	0.15	1	0.13	6.9e-04	6.12	9.19e-10	0.06	FALSE
OFC	Serpinf2	gene expression	Serpinf2	0.15	1	0.15	2.5e-04	6.03	1.61e-09	0.06	FALSE
OFC	Scarf1	intron excision ratio	chr10_60859670_60862282	0.13	1058	0.12	8.9e-04	5.42	5.82e-08	0.54	FALSE
OFC	Crk	mRNA stability	Crk	0.17	1213	0.14	4.3e-04	5.42	6.04e-08	0.54	FALSE
PL	Rap1gap2	alternative TSS	NM_001401654.1	0.04	1	0.04	5.2e-05	5.61	2.00e-08	0.18	FALSE
PL	Crk	gene expression	Crk	0.22	8	0.21	3.1e-22	6.31	2.73e-10	0.82	TRUE
PL	Doc2b	gene expression	Doc2b	0.25	1	0.18	5.7e-19	-6.22	4.96e-10	0.83	FALSE
PL	Rap1gap2	gene expression	Rap1gap2	0.38	1	0.4	1.1e-46	-5.97	2.31e-09	0.9	FALSE
PL	Rpa1	gene expression	Rpa1	0.05	832	0.03	2.9e-04	5.57	2.59e-08	0.7	FALSE
PL	Rtn4rl1	gene expression	Rtn4rl1	0.09	1	0.1	1.5e-10	-5.93	2.99e-09	0.44	FALSE
PL	Rap1gap2	isoform ratio	NM_001401654.1	0.04	1	0.04	9.8e-06	5.94	2.87e-09	0.79	FALSE
PL	Smyd4	isoform ratio	XM_063268677.1	0.04	1	0.04	3.6e-05	-6.12	9.19e-10	0.3	FALSE
PL	Rap1gap2	intron excision ratio	chr10_59855162_59892814	0.07	10	0.07	6.7e-08	-5.48	4.30e-08	0.49	FALSE
PL	Rph3al	intron excision ratio	chr10_61273145_61331474	0.07	1	0.03	3.8e-04	6.03	1.61e-09	0.2	FALSE
PL	Smyd4	intron excision ratio	chr10_60698680_60699761	0.11	1	0.11	5.2e-12	5.98	2.28e-09	0.48	FALSE
PL	Ccdc92b	mRNA stability	Ccdc92b	0.03	1	0.04	4.3e-05	-5.5	3.90e-08	0.09	FALSE
PL	Crk	mRNA stability	Crk	0.28	13	0.29	1.8e-31	5.95	2.68e-09	0.82	FALSE
PL	Rap1gap2	mRNA stability	Rap1gap2	0.08	1	0.1	1.1e-10	-5.97	2.31e-09	0.9	FALSE
pVTA	Crk	gene expression	Crk	0.18	1	0.17	7.8e-14	-6.09	1.16e-09	0.65	FALSE
pVTA	Doc2b	gene expression	Doc2b	0.17	80	0.06	1.9e-05	-6.25	4.04e-10	0.83	FALSE
pVTA	LOC102549294	gene expression	LOC102549294	0.04	6	0.03	2.8e-03	6.24	4.47e-10	0.65	TRUE
pVTA	Mettl16	gene expression	Mettl16	0.03	7	0.02	8.9e-03	-5.94	2.94e-09	0.47	FALSE
pVTA	Rpa1	gene expression	Rpa1	0.13	1	0.13	7.7e-11	6.25	4.23e-10	0.82	FALSE
pVTA	Slc43a2	gene expression	Slc43a2	0.22	161	0.28	7.3e-23	-5.68	1.31e-08	0.01	FALSE
pVTA	Smyd4	isoform ratio	XM_063268677.1	0.04	1	0.04	2.3e-04	-6.01	1.84e-09	0.05	FALSE
pVTA	Smyd4	intron excision ratio	chr10_60698680_60699761	0.12	79	0.14	1.7e-11	6.05	1.45e-09	0.78	FALSE
pVTA	Crk	mRNA stability	Crk	0.25	1	0.26	3.0e-21	-5.57	2.55e-08	0.09	FALSE
RMTg	Crk	gene expression	Crk	0.18	13	0.12	5.1e-04	6.09	1.16e-09	0.61	FALSE