Best TWAS P=3.446595e-07 · Best GWAS P=2.795304e-07 conditioned to 0.2581898
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Ksr2 | gene expression | ENSRNOG00000028630 | 0.07 | 0.07 | top1 | 1 | 0.07 | 2.4e-07 | -5.1 | 5.1 | 3.4e-07 | -0.92 | 0.15 | 0.83 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.