Tibia length

Tags: Physiology · Bone

Project: lionikas_2014

12 loci · 37 genes with independent associations · 432 total associated genes

Significant Loci

# Chr Start pos End pos # assoc genes # joint models Best TWAS P Best GWAS P Cond GWAS P Joint genes
1 chr1 195840684 197231379 2 2 3.72e-08 9.87e-08 8.33e-03 Chst15
2 chr3 75048537 76416396 1 1 1.25e-07 2.63e-07 1.00e+00 Erich2
3 chr3 107934079 108540443 1 1 1.35e-12 3.19e-02 1.09e-78 Prr5l
4 chr7 28462991 32566822 36 15 2.28e-10 2.66e-10 0.00e+00 Cep83 Cfap54 Fgd6 LOC108351432 LOC134479659 LOC134479863 Lta4h Ndufa12 Nedd1 Nr2c1 Ntn4 Tmcc3 Vezt
5 chr8 117463629 118343328 1 1 8.79e-14 6.65e-02 1.00e+00 Mst1
6 chr8 119067995 120669374 2 1 1.58e-07 3.90e-07 3.40e-01 Lrrfip2
7 chr9 83390749 84777604 1 1 0.00e+00 4.41e-01 1.00e+00 Retreg2
8 chr10 103498083 107706829 343 7 4.05e-14 2.37e-14 NaN Aatk C1qtnf1 Cbx2 Cep131 LOC108352165 Slc25a10 Tbc1d16
9 chr12 5367829 6763187 1 1 1.24e-07 5.01e-06 7.03e-01 LOC134481143
10 chr14 98506917 99904851 1 1 1.91e-07 2.13e-06 1.00e+00 Lgalsl
11 chr14 99985577 101883483 12 1 1.58e-08 3.38e-08 3.53e-01 LOC102552414
12 chr15 53577411 57359085 31 5 7.97e-09 4.05e-09 1.00e+00 Itm2b Lrch1 Nudt15 Rcbtb2

Pleiotropic Associations

Trait Chi2 ratio # genes+ # genes++ % genes++ Corr Corr P Genes
BMI with tail 643.95 5 1 2.7 -1 1.39e-08 Lta4h Plxnc1 Prr5l Retreg2 Vezt
BMI without tail 3352.73 15 2 5.4 0.94 6.22e-21 Cdk17 Cep83 Fgd6 LOC108351432 LOC134479863 LOC134481143 Lta4h Metap2 Mir331 Ndufa12 Nr2c1 Plxnc1 Prr5l Retreg2 Vezt
Body weight 9.32 60 26 70.3 0.63 3.27e-22 Aatk Als2cl Alyref Amdhd1 B3gnt2 B3gntl1 Baiap2 Ccdc137 Ccdc38 Ccdc57 Cdk17 Cep131 Cep83 Cfap54 Eif4a3 Endov Fasn Fgd6 Gaa Gcgr Gps1 LOC102552414 LOC103693493 LOC108351432 LOC108352165 LOC120093559 LOC120095223 LOC120095311 LOC134479659 LOC134479863 LOC134480921 LOC134481143 Lrrfip2 Lta4h Mcrip1 Metap2 Mir331 Mst1 Ndufa12 Nedd1 Nr2c1 Ntn4 Pcyt2 Pde6g Plxnc1 Prr5l Ptchd3 Retreg2 Rnf213 Rpl28l3 Sgsh Slc16a3 Slc25a10 Slc38a10 Snrpf Tmcc3 Tmem17 Tspan10 Vezt Zfp950l6
Epididymis fat weight 54228.13 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Glucose 623.51 4 2 5.4 -0.96 3.92e-02 B3gntl1 Fn3k Mst1 Retreg2
Heart weight 13509 1 1 2.7 0 1.00e+00 Retreg2
Left kidney weight 1704.94 22 8 21.6 -0.86 4.63e-25 Amdhd1 Ccdc38 Cdk17 Cep83 Fgd6 LOC108351432 LOC134479863 LOC134481143 Lta4h Metap2 Mir331 Ndufa12 Nedd1 Nr2c1 Ntn4 Plxnc1 Prr5l Retreg2 Snrpf Tmcc3 Tmem17 Vezt
Right kidney weight 1625.89 23 3 8.1 -0.87 2.79e-23 Amdhd1 B3gnt2 Ccdc38 Cdk17 Cep83 Fgd6 Lgalsl LOC102552414 LOC108351432 LOC134479863 LOC134481143 Lta4h Metap2 Mir331 Mst1 Ndufa12 Nr2c1 Ntn4 Plxnc1 Retreg2 Snrpf Tmem17 Vezt
Tail length 370.35 61 20 54.1 0.81 9.57e-59 Aatk Alyref Amdhd1 Arhgdia Baiap2 Card14 Cbx8 Ccdc137 Ccdc38 Ccdc57 Cd7 Cdk17 Cep131 Cep83 Cfap54 Chmp6 Eif4a3 Endov Fgd6 Fscn2 Gaa Gcgr Hgs LOC100912167 LOC103693493 LOC108351432 LOC108352165 LOC120093559 LOC120095223 LOC120095311 LOC134479659 LOC134479863 LOC134481143 Lta4h Mcrip1 Metap2 Mir331 Ndufa12 Ndufaf8 Nedd1 Npb Nploc4 Nptx1 Nr2c1 Ntn4 Oxld1 Pcyt2 Pde6g Plxnc1 Retreg2 Rfng Rnf213 Rptor Sgsh Slc16a3 Slc25a10 Slc38a10 Snrpf Tmcc3 Tspan10 Vezt
Length with tail 61.69 45 26 70.3 0.98 1.94e-86 Aatk Als2cl Amdhd1 B3gnt2 Baiap2 Cbx8 Ccdc137 Ccdc38 Cdk17 Cep83 Cfap54 Commd1 Eif4a3 Endov Fgd6 Gaa LOC102551272 LOC102552414 LOC108351432 LOC108352165 LOC120093559 LOC134479659 LOC134479863 LOC134481143 Lrrfip2 Lta4h Metap2 Mir331 Mst1 Ndufa12 Nedd1 Nptx1 Nr2c1 Ntn4 Plxnc1 Retreg2 Rnf213 Rptor Sgsh Slc38a10 Snrpf Tbc1d16 Tmcc3 Tmem17 Vezt
Length without tail 1491.77 25 15 40.5 -0.84 1.68e-24 Als2cl Amdhd1 Ccdc38 Cdk17 Cep83 Cfap54 Fgd6 LOC108351432 LOC120093559 LOC134479659 LOC134479863 LOC134481143 Lrrfip2 Lta4h Metap2 Mir331 Mst1 Ndufa12 Nr2c1 Ntn4 Plxnc1 Retreg2 Snrpf Tmcc3 Vezt
Liver weight, left 1824.75 4 2 5.4 -0.97 8.39e-05 Mst1 Ndufa12 Nr2c1 Retreg2
Liver weight, right 143.89 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Parametrial fat weight 615.65 1 1 2.7 0 1.00e+00 Retreg2
Retroperitoneal fat weight 91.29 37 2 5.4 0.9 9.28e-69 Aatk Alyref Anapc11 Arhgdia Baiap2 Card14 Ccdc137 Ccdc57 Cep131 Chmp6 Eif4a3 Endov Fgd6 Gaa Gcgr LOC103693493 LOC108352165 LOC120095223 LOC120095311 Mcrip1 Mst1 Ndufaf8 Npb Nploc4 Nr2c1 Oxld1 Pcyt2 Pde6g Retreg2 Rfng Rnf213 Rptor Sgsh Slc25a10 Slc38a10 Tepsin Tspan10
Intraocular pressure 40071.91 1 1 2.7 0 1.00e+00 Retreg2
Extensor digitorum longus weight 166.06 9 1 2.7 0.9 5.28e-11 Cysltr2 Fndc3a Itm2b LOC134481143 Lpar6 Med4 Nudt15 Rcbtb2 Retreg2
Soleus weight 15.81 4 1 2.7 0.69 1.90e-02 Fndc3a Nudt15 Rcbtb2 Retreg2
Tibialis anterior weight 1634.02 3 2 5.4 0 1.00e+00 LOC134481143 Prr5l Retreg2
Number of licking bursts 157119.65 1 1 2.7 0 1.00e+00 Retreg2
Food consumed during 24 hour testing period 106196.53 1 1 2.7 0 1.00e+00 Retreg2
Times rat made contact with spout 305.36 1 1 2.7 0 1.00e+00 Retreg2
Mean time between licks in bursts 199507.71 1 1 2.7 0 1.00e+00 Retreg2
Mean num. licks in bursts 142600.29 1 1 2.7 0 1.00e+00 Retreg2
Std. dev. time between licks in bursts 94042.02 1 1 2.7 0 1.00e+00 Retreg2
Water consumed over 24 hours 103408.69 1 1 2.7 0 1.00e+00 Retreg2
Patch foraging indifference point 0 sec 115003.89 1 1 2.7 0 1.00e+00 Retreg2
Patch foraging indifference point AUC 44390.72 3 2 5.4 0 1.00e+00 Mst1 Prr5l Retreg2
Indifference point function ln k 71040.92 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Indifference point function log k 71040.92 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Patch foraging total patch changes 0 sec 120264.14 1 1 2.7 0 1.00e+00 Retreg2
Patch foraging total patch changes 12 sec 3637.8 3 2 5.4 0 1.00e+00 Mst1 Prr5l Retreg2
Patch foraging total patch changes 18 sec 58889.67 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Patch foraging total patch changes 24 sec 83554.6 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Patch foraging total patch changes 6 sec 16325.11 2 1 2.7 0 1.00e+00 Prr5l Retreg2
Patch foraging time to switch 0 sec 78318.27 2 2 5.4 0 1.00e+00 Prr5l Retreg2
Patch foraging water rate 0 sec 74407.85 2 2 5.4 0 1.00e+00 Prr5l Retreg2
Patch foraging water rate 12 sec 161858.08 1 1 2.7 0 1.00e+00 Retreg2
Patch foraging water rate 18 sec 51645.28 2 1 2.7 0 1.00e+00 Prr5l Retreg2
Patch foraging water rate 24 sec 4691.77 1 1 2.7 0 1.00e+00 Retreg2
Patch foraging water rate 6 sec 3954.86 1 1 2.7 0 1.00e+00 Retreg2
Locomotor activity 15.72 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Locomotor testing distance 44732.22 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Locomotor testing rearing 76214.5 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Light reinforcement 1 155242.72 1 1 2.7 0 1.00e+00 Retreg2
Light reinforcement 2 53965.57 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Reaction time number correct 153465.22 1 1 2.7 0 1.00e+00 Retreg2
Reaction time mean minus median 205810.62 1 1 2.7 0 1.00e+00 Retreg2
Reaction time mean minus median AUC 104201.52 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Reaction time num false alarms 28542.61 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Reaction time num false alarms AUC 106496.51 1 1 2.7 0 1.00e+00 Retreg2
Reaction time trials correct on left 153465.22 1 1 2.7 0 1.00e+00 Retreg2
Reaction time trials on left 149991.58 1 1 2.7 0 1.00e+00 Retreg2
Reaction time mean 94380.53 1 1 2.7 0 1.00e+00 Retreg2
Reaction time mean AUC 113341.21 1 1 2.7 0 1.00e+00 Retreg2
Median of all reaction times 31417.12 1 1 2.7 0 1.00e+00 Retreg2
Reaction time omissions 34267.91 1 1 2.7 0 1.00e+00 Retreg2
Reaction time false alarm rate 891.26 1 1 2.7 0 1.00e+00 Retreg2
Reaction time premature initiation rate 36877.02 1 1 2.7 0 1.00e+00 Retreg2
Reaction time premature initiations 138718.63 1 1 2.7 0 1.00e+00 Retreg2
Std. dev. reaction times 74746.42 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Reaction time trials completed 149991.58 1 1 2.7 0 1.00e+00 Retreg2
Reaction time trials AUC 151696.42 1 1 2.7 0 1.00e+00 Retreg2
Social response proportion 17657.99 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Social responses 1905.06 3 1 2.7 0 1.00e+00 Mst1 Prr5l Retreg2
Social time 22125.12 2 1 2.7 0 1.00e+00 Prr5l Retreg2
Conditioned locomotion 6074.35 1 1 2.7 0 1.00e+00 Retreg2
Cocaine response after cond. corrected 65812.39 1 1 2.7 0 1.00e+00 Retreg2
Cocaine response after cond. not corrected 64247.35 1 1 2.7 0 1.00e+00 Retreg2
Cocaine response before conditioning 2800.41 1 1 2.7 0 1.00e+00 Retreg2
Saline control response 6522.43 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Condit. Reinf. active minus inactive responses 26712.34 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Condit. Reinf. active-inactive response ratio 91582.24 1 1 2.7 0 1.00e+00 Retreg2
Condit. Reinf. active responses 4856.3 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Condit. Reinf. inactive responses 21067.54 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Condit. Reinf. lever presses 7960.29 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Condit. Reinf. lever reinforcers received 1007.39 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. lever latency 3648.25 3 1 2.7 0 1.00e+00 Mst1 Prr5l Retreg2
Pavlov. Cond. magazine entry latency 24773.4 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. change in total contacts 114781.94 1 1 2.7 0 1.00e+00 Retreg2
Pavlov. Cond. index score 24017.04 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. latency score 29259.45 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. lever contacts 7372.88 3 2 5.4 0 1.00e+00 Mst1 Prr5l Retreg2
Pavlov. Cond. magazine entry number 8453.95 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries 52501.71 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff. 22461.1 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. response bias 2629.8 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Conditioned reinforcement - actives 191492.54 1 1 2.7 0 1.00e+00 Retreg2
Conditioned reinforcement - inactives 77543.68 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Conditioned locomotion 41346.85 1 1 2.7 0 1.00e+00 Retreg2
Intermittent access intake day 1-15 change 105304.97 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Intermittent access intake escalation 104773.43 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Intermittent access intake escalation 2 107995.31 1 1 2.7 0 1.00e+00 Retreg2
Intermitt. access day 1 inactive lever presses 118279.42 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Intermitt. access day 15 inactive lever presses 208241.66 1 1 2.7 0 1.00e+00 Retreg2
Intermitt. access escalation Index 92516.01 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Intermittent access day 1 total infusions 155525.68 1 1 2.7 0 1.00e+00 Retreg2
Intermittent access day 15 total infusions 131485.34 1 1 2.7 0 1.00e+00 Retreg2
Intermittent access terminal intake (last 3 days) 83205.14 1 1 2.7 0 1.00e+00 Retreg2
Intermittent access total infusions 675.9 1 1 2.7 0 1.00e+00 Retreg2
Intermittent access day 1 locomotion 104459.41 1 1 2.7 0 1.00e+00 Retreg2
Intermittent access day 15 total locomotion 177836.92 1 1 2.7 0 1.00e+00 Retreg2
Intermittent access total locomotion 711.59 1 1 2.7 0 1.00e+00 Retreg2
Intermittent access standard deviation 100956.84 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Cocaine induced anxiety 160280.46 1 1 2.7 0 1.00e+00 Retreg2
Post-drug Anxiety 20460.83 1 1 2.7 0 1.00e+00 Retreg2
Baseline Anxiety 103471.3 1 1 2.7 0 1.00e+00 Retreg2
Lifetime Intake 6830.03 1 1 2.7 0 1.00e+00 Retreg2
Incentive Sensitization - Responses 163579.25 1 1 2.7 0 1.00e+00 Retreg2
Incentive Sensitization - Breakpoint 142790.8 1 1 2.7 0 1.00e+00 Retreg2
Progressive ratio test 1 active lever presses 99872.69 1 1 2.7 0 1.00e+00 Retreg2
Progressive ratio test 1 breakpoint 96247.61 1 1 2.7 0 1.00e+00 Retreg2
Progressive ratio test 1 inactive lever presses 75556.75 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Progressive ratio test 2 active lever presses 57222.6 1 1 2.7 0 1.00e+00 Retreg2
Progressive ratio test 2 breakpoint 34975.96 1 1 2.7 0 1.00e+00 Retreg2
Progressive ratio test 2 inactive lever presses 164104.71 1 1 2.7 0 1.00e+00 Retreg2
Total sessions with >9 infusions 3995.08 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Short access day 1 total inactive lever presses 38149.28 3 2 5.4 0 1.00e+00 Mst1 Prr5l Retreg2
Short access day 10 total inactive lever presses 108578.43 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Short access day 1 total infusions 111479.43 1 1 2.7 0 1.00e+00 Retreg2
Short access day 10 total infusions 38157.63 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Short access total infusions 33946.03 1 1 2.7 0 1.00e+00 Retreg2
Short access day 1 locomotion 42032.93 2 1 2.7 0 1.00e+00 Prr5l Retreg2
Short access day 10 total locomotion 90801.14 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Short access total locomotion 22766.31 3 2 5.4 0 1.00e+00 Mst1 Prr5l Retreg2
Compulsive drug intake 65439.45 1 1 2.7 0 1.00e+00 Retreg2
One hour access (0.3 mA shock) 9669.44 1 1 2.7 0 1.00e+00 Retreg2
One hour access (shock baseline) 140263.4 1 1 2.7 0 1.00e+00 Retreg2
Number of responses in last shaping day 25656.23 2 2 5.4 0 1.00e+00 Prr5l Retreg2
Context. condit. distance diff. score 970.59 1 1 2.7 0 1.00e+00 Retreg2
Locomotion velocity, session 1 14615.25 1 1 2.7 0 1.00e+00 Retreg2
Locomotion distance, session 1 4416.18 1 1 2.7 0 1.00e+00 Retreg2
Locomotion velocity, session 2 4702.2 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Locomotion distance, session 2 2393.66 1 1 2.7 0 1.00e+00 Retreg2
Locomotion velocity, session 3 1177.39 2 1 2.7 0 1.00e+00 Prr5l Retreg2
Locomotion distance, session 3 16615.78 1 1 2.7 0 1.00e+00 Retreg2
Stereotopy head waving bouts, day 3 1968.48 3 1 2.7 0 1.00e+00 Mst1 Prr5l Retreg2
Stereotopy head waving duration, day 3 6074.03 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Locomotion velocity, session 7 708.6 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Locomotion distance, session 7 1934.91 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Stereotopy head waving bouts, day 7 10466.92 1 1 2.7 0 1.00e+00 Retreg2
Stereotopy head waving duration, day 7 8847.36 1 1 2.7 0 1.00e+00 Retreg2
Locomotion velocity, session 8 1892.98 1 1 2.7 0 1.00e+00 Retreg2
Locomotion distance, session 8 673.32 1 1 2.7 0 1.00e+00 Retreg2
Degree of sensitization distance 7696.03 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Degree of sensitization stereotypy 8496.38 1 1 2.7 0 1.00e+00 Retreg2
Condit. Reinf. active minus inactive responses 2077.92 2 2 5.4 0 1.00e+00 Prr5l Retreg2
Condit. Reinf. active-inactive response ratio 558.58 2 1 2.7 0 1.00e+00 Prr5l Retreg2
Condit. Reinf. active responses 5847.95 2 2 5.4 0 1.00e+00 Prr5l Retreg2
Condit. Reinf. inactive responses 19375.3 1 1 2.7 0 1.00e+00 Retreg2
Incentive salience index mean 4947.1 3 2 5.4 0 1.00e+00 Mst1 Prr5l Retreg2
Condit. Reinf. lever presses 7168.4 3 3 8.1 0 1.00e+00 Mst1 Prr5l Retreg2
Time in familiar zone, hab. session 1 41873.03 1 1 2.7 0 1.00e+00 Retreg2
Time in novel zone, hab. session 1 11855.76 3 2 5.4 0 1.00e+00 Mst1 Prr5l Retreg2
Total zone transitions, hab. session 1 1818.53 1 1 2.7 0 1.00e+00 Retreg2
Total locomotion distance, hab. session 1 1687 1 1 2.7 0 1.00e+00 Retreg2
Locomotion velocity, hab. session 1 1131.06 1 1 2.7 0 1.00e+00 Retreg2
Time in familiar zone, hab. session 2 11707.23 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Time in novel zone, hab. session 2 12499.19 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Total zone transitions, hab. session 2 280.53 1 1 2.7 0 1.00e+00 Retreg2
Total locomotion distance, hab. session 2 55.8 2 1 2.7 0 1.00e+00 Prr5l Retreg2
Locomotion velocity, hab. session 2 79.6 2 1 2.7 0 1.00e+00 Prr5l Retreg2
Novel to familiar place preference ratio 18514.75 3 1 2.7 0 1.00e+00 Mst1 Prr5l Retreg2
Novelty place preference 18140.34 3 1 2.7 0 1.00e+00 Mst1 Prr5l Retreg2
Time in novel zone, NPP test 13626.92 3 1 2.7 0 1.00e+00 Mst1 Prr5l Retreg2
Total zone transitions, NPP test 8230.03 1 1 2.7 0 1.00e+00 Retreg2
Total locomotion distance, NPP test 7114 1 1 2.7 0 1.00e+00 Retreg2
Locomotion velocity, NPP test 4041.22 1 1 2.7 0 1.00e+00 Retreg2
Pavlov. Cond. lever latency 1120.34 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. change in total contacts 2281.88 2 1 2.7 0 1.00e+00 Prr5l Retreg2
Pavlov. Cond. index score 899.58 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. latency score 628.33 3 2 5.4 0 1.00e+00 Mst1 Prr5l Retreg2
Pavlov. Cond. lever contacts 1539.83 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. magazine entry number 1093.11 2 2 5.4 0 1.00e+00 Prr5l Retreg2
Pavlov. Cond. intertrial magazine entries 198.69 3 3 8.1 0 1.00e+00 Mst1 Prr5l Retreg2
Pavlov. Cond. lever-magazine prob. diff. 979.4 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. response bias 880.36 3 1 2.7 0 1.00e+00 Mst1 Prr5l Retreg2
Bone: apparent density 22268.03 1 1 2.7 0 1.00e+00 Retreg2
Bone surface 8383.75 3 2 5.4 0 1.00e+00 Mst1 Prr5l Retreg2
Bone volume 33831.7 1 1 2.7 0 1.00e+00 Retreg2
Bone: connectivity density 3566.21 2 2 5.4 0 1.00e+00 Prr5l Retreg2
Bone: cortical apparent density 45266.32 1 1 2.7 0 1.00e+00 Retreg2
Bone: cortical area 1472 8 3 8.1 0.99 5.71e-11 B3gntl1 Ccdc57 Fn3k Mst1 Rab40b Retreg2 Slc16a3 Zfp950l6
Bone: cortical porosity 932.97 2 2 5.4 0 1.00e+00 Prr5l Retreg2
Bone: cortical porosity 2417.92 2 2 5.4 0 1.00e+00 Prr5l Retreg2
Bone: cortical thickness 73.67 15 6 16.2 -0.7 3.52e-05 Afmid Ccdc57 Cd7 Cenpx Engase Fasn Mst1 Rab40b Rbfox3 Retreg2 Slc16a3 Timp2 Usp36 Uts2r Zfp950l6
Bone: cortical thickness 6116.53 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Bone: cortical tissue density 48453.42 1 1 2.7 0 1.00e+00 Retreg2
Bone: elastic displacement 29626.25 1 1 2.7 0 1.00e+00 Retreg2
Bone: elastic work 84.3 16 3 8.1 -0.77 5.29e-05 Ccdc137 Ccdc57 Cd7 Cenpx Fasn Gps1 Lrrc45 Mcrip1 Mst1 Narf Rab40b Retreg2 Slc16a3 Slc38a10 Tepsin Uts2r
Bone: endosteal estimation 35257.61 1 1 2.7 0 1.00e+00 Retreg2
Bone: endosteal perimeter 2986.84 9 2 5.4 0.98 4.61e-11 Afmid Birc5 C1qtnf1 Dnah17 Lgals3bp LOC102548046 Pgs1 Retreg2 Tmem235
Bone: final force 483.1 9 3 8.1 1 5.05e-15 B3gntl1 Ccdc57 Fn3k Mst1 Ptchd3 Rab40b Retreg2 Slc16a3 Zfp950l6
Bone: final moment 45.39 17 3 8.1 0.98 2.30e-21 B3gntl1 Ccdc57 Cenpx Csnk1d Dcxr Fasn Fn3k Gps1 LOC134480921 Mcrip1 Mst1 Ptchd3 Rab40b Retreg2 Slc16a3 Tbcd Zfp950l6
Bone: marrow area 37067.95 1 1 2.7 0 1.00e+00 Retreg2
Bone: maximum diameter 287.21 18 2 5.4 0.94 2.05e-43 Afmid Birc5 C1qtnf1 Cyth1 Dnah17 Lgals3bp LOC100912319 LOC102548046 LOC120095218 Mst1 Pgs1 Retreg2 Syngr2 Tha1 Tk1 Tmc6 Tmem235 Tnrc6c
Bone: maximum force 1451.52 13 4 10.8 0.98 6.18e-16 B3gntl1 Ccdc57 Fasn Fn3k Gps1 LOC134480921 Mst1 Ptchd3 Rab40b Retreg2 Slc16a3 Tbcd Zfp950l6
Bone: maximum moment 629.27 18 5 13.5 0.97 3.40e-24 B3gntl1 Ccdc57 Cenpx Csnk1d Dcxr Fasn Fn3k Gps1 LOC134480921 Metrnl Mst1 Ptchd3 Rab40b Retreg2 Slc16a3 Tbcd Zfp950l11 Zfp950l6
Bone: minimum diameter 8606.13 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Bone: periosteal estimation 9560.62 4 2 5.4 1 4.31e-03 B3gntl1 Mst1 Retreg2 Zfp950l6
Bone: periosteal perimeter 1401.96 15 2 5.4 0.97 2.77e-19 Afmid Birc5 Cyth1 Dnah17 LOC120095218 Mst1 Pgs1 Rab40b Retreg2 Syngr2 Tha1 Tmc6 Tmem235 Tnrc6c Zfp950l6
Bone: post-yield work 50847.58 1 1 2.7 0 1.00e+00 Retreg2
Bone: stiffness 17808.98 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Bone: tissue strength 12264.67 1 1 2.7 0 1.00e+00 Retreg2
Bone: trabecular number 41138.39 1 1 2.7 0 1.00e+00 Retreg2
Bone: trabecular spacing 15656.57 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Bone: trabecular thickness 16647.3 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Bone: trabecular tissue density 17883.86 3 3 8.1 0 1.00e+00 Mst1 Prr5l Retreg2
Breakpoint value in progressive ratio session 112428.06 1 1 2.7 0 1.00e+00 Retreg2
Distance traveled before self-admin 134013.73 1 1 2.7 0 1.00e+00 Retreg2
Distance traveled after self-admin 100820.36 1 1 2.7 0 1.00e+00 Retreg2
Delta time in closed arm before/after self-admin 1271.86 1 1 2.7 0 1.00e+00 Retreg2
Delta time in open arm before/after self-admin 54811.83 1 1 2.7 0 1.00e+00 Retreg2
Diff in mean of infusions in LGA sessions 54252.87 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Extinction: sum of active levers before priming 45807.86 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Active lever presses in extinction session 6 1571.88 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Delta distance traveled before/after self-admin 12434.77 1 1 2.7 0 1.00e+00 Retreg2
Delta ambulatory time before/after self-admin 96034.01 1 1 2.7 0 1.00e+00 Retreg2
Time in closed arm before self-admin 44133.6 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Time in closed arm after self-admin 9759.54 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Time in open arm before self-admin 34587.99 1 1 2.7 0 1.00e+00 Retreg2
Time in open arm after self-admin 979.73 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Sum of active levers in priming session hrs 5-6 3877.89 1 1 2.7 0 1.00e+00 Retreg2
Time to tail flick, vehicle, before self-admin 25677.46 2 1 2.7 0 1.00e+00 Mst1 Retreg2
Time to tail flick, vehicle, after self-admin 118286.85 1 1 2.7 0 1.00e+00 Retreg2
Time to tail flick, test, before self-admin 32803.11 1 1 2.7 0 1.00e+00 Retreg2
Time to tail flick, test, after self-admin 5828.87 1 1 2.7 0 1.00e+00 Retreg2
Delta time to tail flick, vehicle, before/after SA 18281.67 2 2 5.4 0 1.00e+00 Mst1 Retreg2
Delta time to tail flick, test, before/after SA 56832.34 1 1 2.7 0 1.00e+00 Retreg2
Ambulatory time before self-admin 171079.71 1 1 2.7 0 1.00e+00 Retreg2
Ambulatory time after self-admin 88230.17 1 1 2.7 0 1.00e+00 Retreg2
Total heroin consumption 961.5 1 1 2.7 0 1.00e+00 Retreg2
Area under the delay curve 81605.23 1 1 2.7 0 1.00e+00 Retreg2
Delay disc. indifference point, 0s delay 9477.47 1 1 2.7 0 1.00e+00 Retreg2
Delay disc. indifference point, 16s delay 74803.61 1 1 2.7 0 1.00e+00 Retreg2
Delay disc. indifference point, 2s delay 825.84 1 1 2.7 0 1.00e+00 Retreg2
Delay disc. indifference point, 24s delay 99983.64 1 1 2.7 0 1.00e+00 Retreg2
Delay disc. indifference point, 4s delay 2525.7 1 1 2.7 0 1.00e+00 Retreg2
Delay disc. indifference point, 8s delay 101423.99 1 1 2.7 0 1.00e+00 Retreg2
Delay discount exponential model param 60214.95 1 1 2.7 0 1.00e+00 Retreg2
Delay discount hyperbolic model param 45715.54 1 1 2.7 0 1.00e+00 Retreg2
Fecal boli incidents, locomotor time 1 150160.89 1 1 2.7 0 1.00e+00 Retreg2
Change in fecal boli incidents, locomotor task 23481.3 1 1 2.7 0 1.00e+00 Retreg2
Time >=10cm from walls, locomotor time 1 49255.61 1 1 2.7 0 1.00e+00 Retreg2
Bouts of movement, locomotor time 1 41590.88 1 1 2.7 0 1.00e+00 Retreg2
Total resting periods, locomotor time 1 11802.64 1 1 2.7 0 1.00e+00 Retreg2
Rest time, locomotor task time 1 75951.88 1 1 2.7 0 1.00e+00 Retreg2
Distance moved, locomotor task time 1 159283.67 1 1 2.7 0 1.00e+00 Retreg2
Vertical activity count, locomotor time 1 219061.96 1 1 2.7 0 1.00e+00 Retreg2
Time >=10cm from walls, locomotor time 2 161986.9 1 1 2.7 0 1.00e+00 Retreg2
Bouts of movement, locomotor time 2 174298.32 1 1 2.7 0 1.00e+00 Retreg2
Total resting periods, locomotor time 2 190079.87 1 1 2.7 0 1.00e+00 Retreg2
Rest time, locomotor task time 2 83778.18 1 1 2.7 0 1.00e+00 Retreg2
Distance moved, locomotor task time 2 34268.85 1 1 2.7 0 1.00e+00 Retreg2
Vertical activity count, locomotor time 2 138414.05 1 1 2.7 0 1.00e+00 Retreg2
Weight adjusted by age 161973.18 1 1 2.7 0 1.00e+00 Retreg2
Seeking ratio, delayed vs. immediate footshock 49395.56 1 1 2.7 0 1.00e+00 Retreg2
Locomotion in novel chamber 8159.66 2 1 2.7 0 1.00e+00 Prr5l Retreg2
Locomotion in novel chamber post-restriction 154642.04 1 1 2.7 0 1.00e+00 Retreg2
Progressive ratio 157894.89 1 1 2.7 0 1.00e+00 Retreg2
Food seeking constrained by brief footshock 444.28 8 1 2.7 -1 1.22e-19 Cysltr2 Fndc3a Itm2b Lpar6 Med4 Nudt15 Rcbtb2 Retreg2
Seeking ratio, punishment vs. effort 118281.2 1 1 2.7 0 1.00e+00 Retreg2
Run reversals in cocaine runway, females 37174.37 1 1 2.7 0 1.00e+00 Retreg2
Run reversals in cocaine runway, males 29861.56 1 1 2.7 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway 58575.8 1 1 2.7 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway, F 28379.24 1 1 2.7 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway, M 7140.1 1 1 2.7 0 1.00e+00 Retreg2
Co content in liver 2368.81 2 1 2.7 0 1.00e+00 Prr5l Retreg2
Cu content in liver 162.43 1 1 2.7 0 1.00e+00 Retreg2
Fe content in liver 5656.2 1 1 2.7 0 1.00e+00 Retreg2
K content in liver 6593.53 1 1 2.7 0 1.00e+00 Retreg2
Mg content in liver 24493.99 1 1 2.7 0 1.00e+00 Retreg2
Mn content in liver 4374.36 1 1 2.7 0 1.00e+00 Retreg2
Na content in liver 16641.94 1 1 2.7 0 1.00e+00 Retreg2
Rb content in liver 428.45 1 1 2.7 0 1.00e+00 Retreg2
Zn content in liver 15755.62 1 1 2.7 0 1.00e+00 Retreg2

Associations by panel

Tissue RNA modality # hits % hits/tests Avg chisq
Adipose alternative polyA 15 0.4 2.76
Adipose alternative TSS 16 0.4 2.64
Adipose gene expression 42 0.4 2.69
Adipose isoform ratio 17 0.4 2.68
Adipose intron excision ratio 12 0.4 2.85
Adipose mRNA stability 21 0.5 2.72
BLA alternative polyA 5 0.2 2.84
BLA alternative TSS 6 0.3 2.72
BLA gene expression 22 0.3 2.69
BLA isoform ratio 15 0.5 2.75
BLA intron excision ratio 5 0.2 2.82
BLA mRNA stability 10 0.4 2.76
Brain alternative polyA 9 0.2 2.63
Brain alternative TSS 13 0.3 2.82
Brain gene expression 24 0.2 2.7
Brain isoform ratio 19 0.3 2.74
Brain intron excision ratio 21 0.3 2.95
Brain mRNA stability 17 0.3 2.72
Eye alternative polyA 0 0 2.87
Eye alternative TSS 0 0 2.77
Eye gene expression 2 0.2 2.88
Eye isoform ratio 1 0.2 2.77
Eye intron excision ratio 4 0.4 2.39
Eye mRNA stability 1 0.3 3.01
IC alternative polyA 6 0.3 2.82
IC alternative TSS 7 0.4 2.94
IC gene expression 19 0.3 2.79
IC isoform ratio 8 0.3 2.86
IC intron excision ratio 11 0.3 3.02
IC mRNA stability 6 0.4 2.71
IL alternative polyA 6 0.5 2.91
IL alternative TSS 2 0.3 2.85
IL gene expression 11 0.3 2.73
IL isoform ratio 3 0.2 2.89
IL intron excision ratio 2 0.2 2.98
IL mRNA stability 5 0.4 2.75
LHb alternative polyA 3 0.3 2.8
LHb alternative TSS 1 0.1 2.38
LHb gene expression 11 0.3 2.81
LHb isoform ratio 1 0.1 2.85
LHb intron excision ratio 5 0.4 2.74
LHb mRNA stability 3 0.2 2.67
Liver alternative polyA 16 0.6 2.91
Liver alternative TSS 20 0.7 2.69
Liver gene expression 32 0.4 2.74
Liver isoform ratio 28 0.8 2.89
Liver intron excision ratio 28 0.6 2.78
Liver mRNA stability 19 0.6 2.88
NAcc alternative polyA 8 0.2 5.36
NAcc alternative TSS 9 0.2 2.84
NAcc gene expression 33 0.3 2.74
NAcc isoform ratio 24 0.5 2.89
NAcc intron excision ratio 21 0.3 2.88
NAcc mRNA stability 12 0.3 2.75
OFC alternative polyA 0 0 2.86
OFC alternative TSS 1 0.1 2.91
OFC gene expression 12 0.3 2.69
OFC isoform ratio 1 0.1 2.63
OFC intron excision ratio 0 0 2.94
OFC mRNA stability 6 0.5 2.81
PL alternative polyA 13 0.4 2.87
PL alternative TSS 5 0.1 2.84
PL gene expression 29 0.3 2.77
PL isoform ratio 15 0.3 2.78
PL intron excision ratio 15 0.3 2.96
PL mRNA stability 17 0.4 2.71
pVTA alternative polyA 6 0.2 2.75
pVTA alternative TSS 9 0.4 2.88
pVTA gene expression 26 0.3 2.79
pVTA isoform ratio 8 0.2 2.74
pVTA intron excision ratio 9 0.2 2.87
pVTA mRNA stability 8 0.3 2.74
RMTg alternative polyA 0 0 2.7
RMTg alternative TSS 1 0.2 3.19
RMTg gene expression 5 0.2 2.68
RMTg isoform ratio 0 0 2.83
RMTg intron excision ratio 2 0.2 2.96
RMTg mRNA stability 1 0.2 2.66