Hub : Traits

Tibia length

Tags: Physiology · Bone

Project: lionikas_2014

12 loci · 30 genes with independent associations · 435 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr1	195840684	197231379	2	2	3.72e-08	9.87e-08	8.33e-03	Chst15
2	chr3	75048537	76416396	1	1	1.25e-07	2.63e-07	1.00e+00	Erich2
3	chr3	107934079	108540443	1	1	1.35e-12	3.19e-02	1.09e-78	Prr5l
4	chr7	28462991	32566822	36	10	2.28e-10	2.66e-10	1.00e+00	Cep83 Elk3 Fgd6 LOC134479659 Lta4h Ndufa12 Plxnc1 Vezt
5	chr8	117463629	120669374	4	2	6.05e-17	3.90e-07	6.66e-01	Map4 Mst1
6	chr9	83390749	84777604	1	1	0.00e+00	4.41e-01	1.00e+00	Retreg2
7	chr10	103498083	107706829	344	5	4.05e-14	2.37e-14	NaN	Ccdc137 Csnk1d Lgals3bp Pgs1 Tbc1d16
8	chr12	5367829	6763187	1	1	1.23e-07	5.01e-06	1.00e+00	LOC134481143
9	chr14	79606129	81004825	1	1	6.56e-08	8.55e-04	1.23e-01	Grk4
10	chr14	98506917	99904851	1	1	1.91e-07	2.13e-06	1.00e+00	Lgalsl
11	chr14	99985577	101883483	12	1	1.58e-08	3.38e-08	1.00e+00	LOC102552414
12	chr15	53577411	57359085	31	4	7.97e-09	4.05e-09	1.00e+00	LOC102546539 Nudt15 Rcbtb2

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	148.71	5	1	3.3	-0.88	1.99e-02	Lta4h Plxnc1 Prr5l Retreg2 Vezt
BMI without tail	1250.86	16	2	6.7	0.83	1.39e-12	Cdk17 Cep83 Elk3 Fgd6 LOC108351432 LOC134479863 LOC134481143 Lta4h Metap2 Mir331 Ndufa12 Nr2c1 Plxnc1 Prr5l Retreg2 Vezt
Body weight	9.38	61	28	93.3	0.94	6.83e-91	Aatk Als2cl Alyref Amdhd1 B3gnt2 B3gntl1 Baiap2 Ccdc137 Ccdc38 Ccdc57 Cdk17 Cep131 Cep83 Cfap54 Eif4a3 Elk3 Endov Fasn Fgd6 Gaa Gcgr Gps1 LOC102552414 LOC103693493 LOC108351432 LOC108352165 LOC120093559 LOC120095223 LOC120095311 LOC134479659 LOC134479863 LOC134480921 LOC134481143 Lrrfip2 Lta4h Map4 Mcrip1 Metap2 Mir331 Mst1 Ndufa12 Nedd1 Nr2c1 Ntn4 Pcyt2 Pde6g Plxnc1 Prr5l Ptchd3 Rnf213 Rpl28l3 Sgsh Slc16a3 Slc25a10 Slc38a10 Snrpf Tmcc3 Tmem17 Tspan10 Vezt Zfp950l6
Epididymis fat weight	18149.94	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Glucose	173.62	4	2	6.7	-0.76	2.36e-01	B3gntl1 Fn3k Mst1 Retreg2
Heart weight	3065.65	1	1	3.3	0	1.00e+00	Retreg2
Left kidney weight	668.46	23	9	30	-0.63	2.61e-10	Amdhd1 Ccdc38 Cdk17 Cep83 Elk3 Fgd6 LOC108351432 LOC134479863 LOC134481143 Lta4h Metap2 Mir331 Ndufa12 Nedd1 Nr2c1 Ntn4 Plxnc1 Prr5l Retreg2 Snrpf Tmcc3 Tmem17 Vezt
Right kidney weight	558.11	24	3	10	-0.63	1.83e-09	Amdhd1 B3gnt2 Ccdc38 Cdk17 Cep83 Elk3 Fgd6 Lgalsl LOC102552414 LOC108351432 LOC134479863 LOC134481143 Lta4h Metap2 Mir331 Mst1 Ndufa12 Nr2c1 Ntn4 Plxnc1 Retreg2 Snrpf Tmem17 Vezt
Tail length	121.84	62	21	70	0.66	2.08e-32	Aatk Alyref Amdhd1 Arhgdia Baiap2 Card14 Cbx8 Ccdc137 Ccdc38 Ccdc57 Cd7 Cdk17 Cep131 Cep83 Cfap54 Chmp6 Eif4a3 Elk3 Endov Fgd6 Fscn2 Gaa Gcgr Hgs LOC100912167 LOC103693493 LOC108351432 LOC108352165 LOC120093559 LOC120095223 LOC120095311 LOC134479659 LOC134479863 LOC134481143 Lta4h Mcrip1 Metap2 Mir331 Ndufa12 Ndufaf8 Nedd1 Npb Nploc4 Nptx1 Nr2c1 Ntn4 Oxld1 Pcyt2 Pde6g Plxnc1 Retreg2 Rfng Rnf213 Rptor Sgsh Slc16a3 Slc25a10 Slc38a10 Snrpf Tmcc3 Tspan10 Vezt
Length with tail	23.81	47	28	93.3	0.96	5.24e-69	Aatk Als2cl Amdhd1 B3gnt2 Baiap2 Cbx8 Ccdc137 Ccdc38 Cdk17 Cep83 Cfap54 Commd1 Eif4a3 Elk3 Endov Fgd6 Gaa LOC102551272 LOC102552414 LOC108351432 LOC108352165 LOC120093559 LOC134479659 LOC134479863 LOC134481143 Lrrfip2 Lta4h Map4 Metap2 Mir331 Mst1 Ndufa12 Nedd1 Nptx1 Nr2c1 Ntn4 Plxnc1 Retreg2 Rnf213 Rptor Sgsh Slc38a10 Snrpf Tbc1d16 Tmcc3 Tmem17 Vezt
Length without tail	545.6	27	15	50	-0.58	3.39e-09	Als2cl Amdhd1 Ccdc38 Cdk17 Cep83 Cfap54 Elk3 Fgd6 LOC108351432 LOC120093559 LOC134479659 LOC134479863 LOC134481143 Lrrfip2 Lta4h Map4 Metap2 Mir331 Mst1 Ndufa12 Nr2c1 Ntn4 Plxnc1 Retreg2 Snrpf Tmcc3 Vezt
Liver weight, left	447.31	4	2	6.7	-0.89	2.71e-03	Mst1 Ndufa12 Nr2c1 Retreg2
Liver weight, right	44.57	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Parametrial fat weight	181.56	1	1	3.3	0	1.00e+00	Retreg2
Retroperitoneal fat weight	26.28	37	2	6.7	0.82	1.00e-46	Aatk Alyref Anapc11 Arhgdia Baiap2 Card14 Ccdc137 Ccdc57 Cep131 Chmp6 Eif4a3 Endov Fgd6 Gaa Gcgr LOC103693493 LOC108352165 LOC120095223 LOC120095311 Mcrip1 Mst1 Ndufaf8 Npb Nploc4 Nr2c1 Oxld1 Pcyt2 Pde6g Retreg2 Rfng Rnf213 Rptor Sgsh Slc25a10 Slc38a10 Tepsin Tspan10
Intraocular pressure	10386.52	1	1	3.3	0	1.00e+00	Retreg2
Extensor digitorum longus weight	39.45	11	1	3.3	0.62	1.84e-04	Cysltr2 Fndc3a Itm2b LOC134481143 Lpar6 Med4 Mst1 Nudt15 Rb1 Rcbtb2 Retreg2
Soleus weight	7.18	4	1	3.3	0.28	3.99e-01	Fndc3a Nudt15 Rcbtb2 Retreg2
Tibialis anterior weight	392.94	3	2	6.7	0	1.00e+00	LOC134481143 Prr5l Retreg2
Number of licking bursts	67424.86	1	1	3.3	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	17761.06	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Times rat made contact with spout	71.66	1	1	3.3	0	1.00e+00	Retreg2
Mean time between licks in bursts	111630.35	1	1	3.3	0	1.00e+00	Retreg2
Mean num. licks in bursts	56750.08	1	1	3.3	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	14881.26	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Water consumed over 24 hours	34168.6	1	1	3.3	0	1.00e+00	Retreg2
Patch foraging indifference point 0 sec	19591.07	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Patch foraging indifference point AUC	16747.73	3	2	6.7	0	1.00e+00	Mst1 Prr5l Retreg2
Indifference point function ln k	27906.36	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Indifference point function log k	27906.36	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 0 sec	41947.04	1	1	3.3	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	794.18	3	2	6.7	0	1.00e+00	Mst1 Prr5l Retreg2
Patch foraging total patch changes 18 sec	20236.6	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 24 sec	37424.62	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 6 sec	3899.43	2	1	3.3	0	1.00e+00	Prr5l Retreg2
Patch foraging time to switch 0 sec	33261.5	2	2	6.7	0	1.00e+00	Prr5l Retreg2
Patch foraging water rate 0 sec	30220.47	2	2	6.7	0	1.00e+00	Prr5l Retreg2
Patch foraging water rate 12 sec	70639.93	1	1	3.3	0	1.00e+00	Retreg2
Patch foraging water rate 18 sec	16871.85	2	1	3.3	0	1.00e+00	Prr5l Retreg2
Patch foraging water rate 24 sec	523.92	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Patch foraging water rate 6 sec	837.86	1	1	3.3	0	1.00e+00	Retreg2
Locomotor activity	26.79	1	1	3.3	0	1.00e+00	Mst1
Locomotor testing distance	13845.45	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Locomotor testing rearing	31715.18	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Light reinforcement 1	66311.75	1	1	3.3	0	1.00e+00	Retreg2
Light reinforcement 2	18398.05	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Reaction time number correct	63471.78	1	1	3.3	0	1.00e+00	Retreg2
Reaction time mean minus median	119950.29	1	1	3.3	0	1.00e+00	Retreg2
Reaction time mean minus median AUC	62004.19	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Reaction time num false alarms	7685.9	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Reaction time num false alarms AUC	17513.8	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Reaction time trials correct on left	63471.78	1	1	3.3	0	1.00e+00	Retreg2
Reaction time trials on left	60883.54	1	1	3.3	0	1.00e+00	Retreg2
Reaction time mean	29724.21	1	1	3.3	0	1.00e+00	Retreg2
Reaction time mean AUC	38768	1	1	3.3	0	1.00e+00	Retreg2
Median of all reaction times	7893.84	1	1	3.3	0	1.00e+00	Retreg2
Reaction time omissions	8364.84	1	1	3.3	0	1.00e+00	Retreg2
Reaction time false alarm rate	111.7	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Reaction time premature initiation rate	9733.76	1	1	3.3	0	1.00e+00	Retreg2
Reaction time premature initiations	53743.58	1	1	3.3	0	1.00e+00	Retreg2
Std. dev. reaction times	30437.76	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Reaction time trials completed	60883.54	1	1	3.3	0	1.00e+00	Retreg2
Reaction time trials AUC	62130.65	1	1	3.3	0	1.00e+00	Retreg2
Social response proportion	4397.95	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Social responses	433.66	3	1	3.3	0	1.00e+00	Mst1 Prr5l Retreg2
Social time	5831.87	2	1	3.3	0	1.00e+00	Prr5l Retreg2
Conditioned locomotion	1400.08	1	1	3.3	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	19128.47	1	1	3.3	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	18571.31	1	1	3.3	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	3.3	0	1.00e+00	Retreg2
Saline control response	1639.18	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active minus inactive responses	7271.32	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active-inactive response ratio	28713.86	1	1	3.3	0	1.00e+00	Retreg2
Condit. Reinf. active responses	1165.18	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. inactive responses	5466.41	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever presses	1963.38	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever reinforcers received	243.91	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever latency	856.84	3	2	6.7	0	1.00e+00	Mst1 Prr5l Retreg2
Pavlov. Cond. magazine entry latency	6738.25	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. change in total contacts	39811.91	1	1	3.3	0	1.00e+00	Retreg2
Pavlov. Cond. index score	6407.33	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	8109.24	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever contacts	1797.66	3	2	6.7	0	1.00e+00	Mst1 Prr5l Retreg2
Pavlov. Cond. magazine entry number	2097.69	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	17558.57	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	5938.34	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	641.31	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Conditioned reinforcement - actives	100795.1	1	1	3.3	0	1.00e+00	Retreg2
Conditioned reinforcement - inactives	32505.31	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Conditioned locomotion	10334.01	1	1	3.3	0	1.00e+00	Retreg2
Intermittent access intake day 1-15 change	63945.95	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation	63041.23	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation 2	36175.43	1	1	3.3	0	1.00e+00	Retreg2
Intermitt. access day 1 inactive lever presses	90342.67	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Intermitt. access day 15 inactive lever presses	123608.2	1	1	3.3	0	1.00e+00	Retreg2
Intermitt. access escalation Index	46701.01	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Intermittent access day 1 total infusions	33063.01	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Intermittent access day 15 total infusions	48731.91	1	1	3.3	0	1.00e+00	Retreg2
Intermittent access terminal intake (last 3 days)	24800.59	1	1	3.3	0	1.00e+00	Retreg2
Intermittent access total infusions	181.04	1	1	3.3	0	1.00e+00	Retreg2
Intermittent access day 1 locomotion	34964.22	1	1	3.3	0	1.00e+00	Retreg2
Intermittent access day 15 total locomotion	85548.8	1	1	3.3	0	1.00e+00	Retreg2
Intermittent access total locomotion	116.36	1	1	3.3	0	1.00e+00	Retreg2
Intermittent access standard deviation	56995.61	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Cocaine induced anxiety	69097.7	1	1	3.3	0	1.00e+00	Retreg2
Post-drug Anxiety	4753.56	1	1	3.3	0	1.00e+00	Retreg2
Baseline Anxiety	33506.24	1	1	3.3	0	1.00e+00	Retreg2
Lifetime Intake	1655.49	1	1	3.3	0	1.00e+00	Retreg2
Incentive Sensitization - Responses	71347.91	1	1	3.3	0	1.00e+00	Retreg2
Incentive Sensitization - Breakpoint	55273.76	1	1	3.3	0	1.00e+00	Retreg2
Progressive ratio test 1 active lever presses	31979.35	1	1	3.3	0	1.00e+00	Retreg2
Progressive ratio test 1 breakpoint	30292.17	1	1	3.3	0	1.00e+00	Retreg2
Progressive ratio test 1 inactive lever presses	31120.43	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Progressive ratio test 2 active lever presses	15263.76	1	1	3.3	0	1.00e+00	Retreg2
Progressive ratio test 2 breakpoint	8542.35	1	1	3.3	0	1.00e+00	Retreg2
Progressive ratio test 2 inactive lever presses	72504.33	1	1	3.3	0	1.00e+00	Retreg2
Total sessions with >9 infusions	1005.82	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Short access day 1 total inactive lever presses	13171.49	3	2	6.7	0	1.00e+00	Mst1 Prr5l Retreg2
Short access day 10 total inactive lever presses	69453.48	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Short access day 1 total infusions	38385.19	1	1	3.3	0	1.00e+00	Retreg2
Short access day 10 total infusions	11366.61	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Short access total infusions	8778.92	1	1	3.3	0	1.00e+00	Retreg2
Short access day 1 locomotion	12408.44	2	1	3.3	0	1.00e+00	Prr5l Retreg2
Short access day 10 total locomotion	44094.34	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Short access total locomotion	6241.65	3	2	6.7	0	1.00e+00	Mst1 Prr5l Retreg2
Compulsive drug intake	18679.82	1	1	3.3	0	1.00e+00	Retreg2
One hour access (0.3 mA shock)	2329.1	1	1	3.3	0	1.00e+00	Retreg2
One hour access (shock baseline)	54988.81	1	1	3.3	0	1.00e+00	Retreg2
Number of responses in last shaping day	6822.98	2	2	6.7	0	1.00e+00	Prr5l Retreg2
Context. condit. distance diff. score	212.47	1	1	3.3	0	1.00e+00	Retreg2
Locomotion velocity, session 1	3523.61	1	1	3.3	0	1.00e+00	Retreg2
Locomotion distance, session 1	1024.77	1	1	3.3	0	1.00e+00	Retreg2
Locomotion velocity, session 2	1110.36	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 2	508.11	1	1	3.3	0	1.00e+00	Retreg2
Locomotion velocity, session 3	264.95	2	1	3.3	0	1.00e+00	Prr5l Retreg2
Locomotion distance, session 3	4009.46	1	1	3.3	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	467.79	3	1	3.3	0	1.00e+00	Mst1 Prr5l Retreg2
Stereotopy head waving duration, day 3	1446.08	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, session 7	210.64	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 7	507.07	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving bouts, day 7	2509.72	1	1	3.3	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	2115.93	1	1	3.3	0	1.00e+00	Retreg2
Locomotion velocity, session 8	409.23	1	1	3.3	0	1.00e+00	Retreg2
Locomotion distance, session 8	147.88	1	1	3.3	0	1.00e+00	Retreg2
Degree of sensitization distance	1889.61	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Degree of sensitization stereotypy	2042.98	1	1	3.3	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	496.57	2	2	6.7	0	1.00e+00	Prr5l Retreg2
Condit. Reinf. active-inactive response ratio	130.79	2	1	3.3	0	1.00e+00	Prr5l Retreg2
Condit. Reinf. active responses	1398.9	2	2	6.7	0	1.00e+00	Prr5l Retreg2
Condit. Reinf. inactive responses	2347.96	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Incentive salience index mean	1202.81	3	2	6.7	0	1.00e+00	Mst1 Prr5l Retreg2
Condit. Reinf. lever presses	1790.33	3	3	10	0	1.00e+00	Mst1 Prr5l Retreg2
Time in familiar zone, hab. session 1	5593.23	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 1	3096.16	3	3	10	0	1.00e+00	Mst1 Prr5l Retreg2
Total zone transitions, hab. session 1	429.72	1	1	3.3	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	394.1	1	1	3.3	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	266.96	1	1	3.3	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	2966.16	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 2	3208.33	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 2	38.53	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Total locomotion distance, hab. session 2	18.49	2	1	3.3	0	1.00e+00	Prr5l Retreg2
Locomotion velocity, hab. session 2	22.47	2	1	3.3	0	1.00e+00	Prr5l Retreg2
Novel to familiar place preference ratio	5126.88	3	1	3.3	0	1.00e+00	Mst1 Prr5l Retreg2
Novelty place preference	4990.08	3	1	3.3	0	1.00e+00	Mst1 Prr5l Retreg2
Time in novel zone, NPP test	5354.94	2	1	3.3	0	1.00e+00	Prr5l Retreg2
Total zone transitions, NPP test	1935.62	1	1	3.3	0	1.00e+00	Retreg2
Total locomotion distance, NPP test	1687.31	1	1	3.3	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	953.07	1	1	3.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	276.98	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. change in total contacts	531.27	2	1	3.3	0	1.00e+00	Prr5l Retreg2
Pavlov. Cond. index score	214.07	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	154.01	3	2	6.7	0	1.00e+00	Mst1 Prr5l Retreg2
Pavlov. Cond. lever contacts	372.95	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry number	257.89	2	2	6.7	0	1.00e+00	Prr5l Retreg2
Pavlov. Cond. intertrial magazine entries	68.72	3	3	10	0	1.00e+00	Mst1 Prr5l Retreg2
Pavlov. Cond. lever-magazine prob. diff.	223.77	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	208.81	3	2	6.7	0	1.00e+00	Mst1 Prr5l Retreg2
Bone: apparent density	5461.77	1	1	3.3	0	1.00e+00	Retreg2
Bone surface	2076.59	3	2	6.7	0	1.00e+00	Mst1 Prr5l Retreg2
Bone volume	4317.38	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Bone: connectivity density	851.06	2	2	6.7	0	1.00e+00	Prr5l Retreg2
Bone: cortical apparent density	12020.36	1	1	3.3	0	1.00e+00	Retreg2
Bone: cortical area	371.1	8	3	10	0.96	1.11e-07	B3gntl1 Ccdc57 Fn3k Mst1 Rab40b Retreg2 Slc16a3 Zfp950l6
Bone: cortical porosity	230.88	2	2	6.7	0	1.00e+00	Prr5l Retreg2
Bone: cortical porosity	570.83	2	2	6.7	0	1.00e+00	Prr5l Retreg2
Bone: cortical thickness	30.61	14	6	20	-0.14	4.92e-01	Ccdc57 Cd7 Cenpx Engase Fasn Mst1 Rab40b Rbfox3 Retreg2 Slc16a3 Timp2 Usp36 Uts2r Zfp950l6
Bone: cortical thickness	1488.54	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Bone: cortical tissue density	13002.58	1	1	3.3	0	1.00e+00	Retreg2
Bone: elastic displacement	7604.03	1	1	3.3	0	1.00e+00	Retreg2
Bone: elastic work	30.82	16	3	10	-0.31	1.75e-01	Ccdc137 Ccdc57 Cd7 Cenpx Fasn Gps1 Lrrc45 Mcrip1 Mst1 Narf Rab40b Retreg2 Slc16a3 Slc38a10 Tepsin Uts2r
Bone: endosteal estimation	8913.19	1	1	3.3	0	1.00e+00	Retreg2
Bone: endosteal perimeter	706.15	11	2	6.7	0.94	3.27e-08	Afmid Birc5 C1qtnf1 Dnah17 Lgals3bp LOC102548046 Mst1 Pgs1 Retreg2 Tmc8 Tmem235
Bone: final force	122.7	9	3	10	0.98	3.03e-11	B3gntl1 Ccdc57 Fn3k Mst1 Ptchd3 Rab40b Retreg2 Slc16a3 Zfp950l6
Bone: final moment	20.3	17	3	10	0.95	1.93e-16	B3gntl1 Ccdc57 Cenpx Csnk1d Dcxr Fasn Fn3k Gps1 LOC134480921 Mcrip1 Mst1 Ptchd3 Rab40b Retreg2 Slc16a3 Tbcd Zfp950l6
Bone: marrow area	4718.94	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Bone: maximum diameter	81.45	18	2	6.7	0.88	1.57e-29	Afmid Birc5 C1qtnf1 Cyth1 Dnah17 Lgals3bp LOC100912319 LOC102548046 Mst1 Pgs1 Retreg2 Syngr2 Tha1 Tk1 Tmc6 Tmc8 Tmem235 Tnrc6c
Bone: maximum force	376.29	13	4	13.3	0.92	2.99e-10	B3gntl1 Ccdc57 Fasn Fn3k Gps1 LOC134480921 Mst1 Ptchd3 Rab40b Retreg2 Slc16a3 Tbcd Zfp950l6
Bone: maximum moment	162.48	18	5	16.7	0.91	4.14e-16	B3gntl1 Ccdc57 Cenpx Csnk1d Dcxr Fasn Fn3k Gps1 LOC134480921 Metrnl Mst1 Ptchd3 Rab40b Retreg2 Slc16a3 Tbcd Zfp950l11 Zfp950l6
Bone: minimum diameter	2061.38	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Bone: periosteal estimation	2465.24	4	2	6.7	0.98	1.98e-02	B3gntl1 Mst1 Retreg2 Zfp950l6
Bone: periosteal perimeter	390.64	14	2	6.7	0.91	2.56e-12	Afmid Birc5 Cyth1 Dnah17 Mst1 Pgs1 Rab40b Retreg2 Syngr2 Tha1 Tmc6 Tmem235 Tnrc6c Zfp950l6
Bone: post-yield work	6843.13	2	1	3.3	0	1.00e+00	Mst1 Retreg2
Bone: stiffness	4554.23	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Bone: tissue strength	2995.95	1	1	3.3	0	1.00e+00	Retreg2
Bone: trabecular number	10739.78	1	1	3.3	0	1.00e+00	Retreg2
Bone: trabecular spacing	3991.76	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Bone: trabecular thickness	4257.4	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Bone: trabecular tissue density	4865.44	3	3	10	0	1.00e+00	Mst1 Prr5l Retreg2
Breakpoint value in progressive ratio session	37605.61	1	1	3.3	0	1.00e+00	Retreg2
Distance traveled before self-admin	50534.09	1	1	3.3	0	1.00e+00	Retreg2
Distance traveled after self-admin	32464.08	1	1	3.3	0	1.00e+00	Retreg2
Delta time in closed arm before/after self-admin	244.69	1	1	3.3	0	1.00e+00	Retreg2
Delta time in open arm before/after self-admin	15131.21	1	1	3.3	0	1.00e+00	Retreg2
Diff in mean of infusions in LGA sessions	18336.8	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Extinction: sum of active levers before priming	14221.72	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Active lever presses in extinction session 6	384.74	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Delta distance traveled before/after self-admin	2940.47	1	1	3.3	0	1.00e+00	Retreg2
Delta ambulatory time before/after self-admin	30849.75	1	1	3.3	0	1.00e+00	Retreg2
Time in closed arm before self-admin	13457.43	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Time in closed arm after self-admin	2326.29	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Time in open arm before self-admin	8746.25	1	1	3.3	0	1.00e+00	Retreg2
Time in open arm after self-admin	277.78	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Sum of active levers in priming session hrs 5-6	978.69	1	1	3.3	0	1.00e+00	Retreg2
Time to tail flick, vehicle, before self-admin	6696.83	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Time to tail flick, vehicle, after self-admin	42142.71	1	1	3.3	0	1.00e+00	Retreg2
Time to tail flick, test, before self-admin	8139.55	1	1	3.3	0	1.00e+00	Retreg2
Time to tail flick, test, after self-admin	1399.18	1	1	3.3	0	1.00e+00	Retreg2
Delta time to tail flick, vehicle, before/after SA	4924	2	2	6.7	0	1.00e+00	Mst1 Retreg2
Delta time to tail flick, test, before/after SA	15684.59	1	1	3.3	0	1.00e+00	Retreg2
Ambulatory time before self-admin	78874.38	1	1	3.3	0	1.00e+00	Retreg2
Ambulatory time after self-admin	26614.91	1	1	3.3	0	1.00e+00	Retreg2
Total heroin consumption	240.55	1	1	3.3	0	1.00e+00	Retreg2
Area under the delay curve	24791.27	1	1	3.3	0	1.00e+00	Retreg2
Delay disc. indifference point, 0s delay	2159.25	1	1	3.3	0	1.00e+00	Retreg2
Delay disc. indifference point, 16s delay	21959.9	1	1	3.3	0	1.00e+00	Retreg2
Delay disc. indifference point, 2s delay	155.27	1	1	3.3	0	1.00e+00	Retreg2
Delay disc. indifference point, 24s delay	32437.06	1	1	3.3	0	1.00e+00	Retreg2
Delay disc. indifference point, 4s delay	616.19	1	1	3.3	0	1.00e+00	Retreg2
Delay disc. indifference point, 8s delay	33362.4	1	1	3.3	0	1.00e+00	Retreg2
Delay discount exponential model param	16922.54	1	1	3.3	0	1.00e+00	Retreg2
Delay discount hyperbolic model param	12277.65	1	1	3.3	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	61202.36	1	1	3.3	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	5669.94	1	1	3.3	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 1	13009.3	1	1	3.3	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 1	10785.17	1	1	3.3	0	1.00e+00	Retreg2
Total resting periods, locomotor time 1	2793.59	1	1	3.3	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	22349.64	1	1	3.3	0	1.00e+00	Retreg2
Distance moved, locomotor task time 1	68821.85	1	1	3.3	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 1	142354.07	1	1	3.3	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	71159.6	1	1	3.3	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 2	82029.05	1	1	3.3	0	1.00e+00	Retreg2
Total resting periods, locomotor time 2	99042.67	1	1	3.3	0	1.00e+00	Retreg2
Rest time, locomotor task time 2	25503.09	1	1	3.3	0	1.00e+00	Retreg2
Distance moved, locomotor task time 2	8477.87	1	1	3.3	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 2	53555.35	1	1	3.3	0	1.00e+00	Retreg2
Weight adjusted by age	70782.25	1	1	3.3	0	1.00e+00	Retreg2
Seeking ratio, delayed vs. immediate footshock	13445.31	1	1	3.3	0	1.00e+00	Retreg2
Locomotion in novel chamber	1961.07	2	1	3.3	0	1.00e+00	Prr5l Retreg2
Locomotion in novel chamber post-restriction	65422.89	1	1	3.3	0	1.00e+00	Retreg2
Progressive ratio	67888.93	1	1	3.3	0	1.00e+00	Retreg2
Food seeking constrained by brief footshock	123.16	8	1	3.3	-0.99	4.93e-15	Cysltr2 Fndc3a Itm2b Lpar6 Med4 Nudt15 Rcbtb2 Retreg2
Seeking ratio, punishment vs. effort	41283.25	1	1	3.3	0	1.00e+00	Retreg2
Run reversals in cocaine runway, females	9406.04	1	1	3.3	0	1.00e+00	Retreg2
Run reversals in cocaine runway, males	7664.74	1	1	3.3	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway	16290.75	1	1	3.3	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, F	7166.92	1	1	3.3	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	1716.51	1	1	3.3	0	1.00e+00	Retreg2
Co content in liver	574.66	2	1	3.3	0	1.00e+00	Prr5l Retreg2
Cu content in liver	39.92	1	1	3.3	0	1.00e+00	Retreg2
Fe content in liver	1344.53	1	1	3.3	0	1.00e+00	Retreg2
K content in liver	1519.62	1	1	3.3	0	1.00e+00	Retreg2
Mg content in liver	6026.97	1	1	3.3	0	1.00e+00	Retreg2
Mn content in liver	1009.39	1	1	3.3	0	1.00e+00	Retreg2
Na content in liver	4018.36	1	1	3.3	0	1.00e+00	Retreg2
Rb content in liver	87.87	1	1	3.3	0	1.00e+00	Retreg2
Zn content in liver	3745.55	1	1	3.3	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	15	0.4	2.76
Adipose	alternative TSS	16	0.4	2.64
Adipose	gene expression	42	0.4	2.69
Adipose	isoform ratio	17	0.4	2.68
Adipose	intron excision ratio	12	0.4	2.85
Adipose	mRNA stability	22	0.5	2.73
BLA	alternative polyA	5	0.2	2.84
BLA	alternative TSS	6	0.3	2.73
BLA	gene expression	22	0.3	2.71
BLA	isoform ratio	15	0.5	2.77
BLA	intron excision ratio	5	0.2	2.81
BLA	mRNA stability	10	0.4	2.76
Brain	alternative polyA	9	0.2	2.63
Brain	alternative TSS	12	0.3	2.81
Brain	gene expression	24	0.2	2.7
Brain	isoform ratio	19	0.3	2.72
Brain	intron excision ratio	23	0.4	2.95
Brain	mRNA stability	17	0.3	2.71
Eye	alternative polyA	0	0	2.83
Eye	alternative TSS	0	0	2.77
Eye	gene expression	2	0.2	2.91
Eye	isoform ratio	1	0.2	2.77
Eye	intron excision ratio	4	0.4	2.37
Eye	mRNA stability	1	0.3	3
IC	alternative polyA	6	0.3	2.83
IC	alternative TSS	6	0.3	2.94
IC	gene expression	19	0.3	2.79
IC	isoform ratio	8	0.3	2.83
IC	intron excision ratio	10	0.3	3
IC	mRNA stability	6	0.4	2.71
IL	alternative polyA	6	0.5	2.91
IL	alternative TSS	1	0.1	2.8
IL	gene expression	11	0.3	2.72
IL	isoform ratio	4	0.3	2.88
IL	intron excision ratio	2	0.2	2.98
IL	mRNA stability	5	0.4	2.76
LHb	alternative polyA	3	0.3	2.81
LHb	alternative TSS	1	0.1	2.4
LHb	gene expression	10	0.3	2.8
LHb	isoform ratio	1	0.1	2.86
LHb	intron excision ratio	5	0.4	2.74
LHb	mRNA stability	3	0.2	2.67
Liver	alternative polyA	16	0.6	2.92
Liver	alternative TSS	21	0.7	2.69
Liver	gene expression	31	0.4	2.73
Liver	isoform ratio	28	0.8	2.89
Liver	intron excision ratio	28	0.6	2.78
Liver	mRNA stability	19	0.6	2.88
NAcc	alternative polyA	9	0.3	3.44
NAcc	alternative TSS	9	0.2	2.82
NAcc	gene expression	32	0.3	2.74
NAcc	isoform ratio	24	0.5	2.88
NAcc	intron excision ratio	21	0.3	2.87
NAcc	mRNA stability	12	0.3	2.76
OFC	alternative polyA	0	0	2.87
OFC	alternative TSS	1	0.1	2.95
OFC	gene expression	13	0.3	2.7
OFC	isoform ratio	1	0.1	2.64
OFC	intron excision ratio	0	0	2.93
OFC	mRNA stability	6	0.5	2.81
PL	alternative polyA	13	0.4	2.88
PL	alternative TSS	5	0.2	2.86
PL	gene expression	29	0.3	2.77
PL	isoform ratio	14	0.3	2.78
PL	intron excision ratio	17	0.3	2.96
PL	mRNA stability	17	0.5	2.71
pVTA	alternative polyA	6	0.2	2.74
pVTA	alternative TSS	9	0.4	2.88
pVTA	gene expression	26	0.3	2.79
pVTA	isoform ratio	8	0.2	2.74
pVTA	intron excision ratio	10	0.2	2.88
pVTA	mRNA stability	8	0.3	2.73
RMTg	alternative polyA	0	0	2.72
RMTg	alternative TSS	1	0.2	3.27
RMTg	gene expression	4	0.2	2.69
RMTg	isoform ratio	0	0	2.86
RMTg	intron excision ratio	1	0.1	2.9
RMTg	mRNA stability	1	0.2	2.7