Hub : Genes

Brca2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Brca2 0.37 0.14 0.0e+00 0.17 0.23 0.23 0.23 2.3e-18 8.0e-25 1.2e-25 3.7e-25
2 BLA mRNA stability Brca2 0.39 0.14 1.0e-14 0.26 0.28 0.29 0.28 4.8e-14 2.6e-15 1.6e-15 2.2e-15
3 Liver mRNA stability Brca2 0.19 0.09 5.6e-17 0.11 0.14 0.14 0.14 1.4e-12 2.2e-15 1.6e-15 1.2e-15
4 Adipose alternative polyA XM_039089544.2 0.03 0.02 5.5e-03 0.02 0.01 0.01 0.01 5.5e-03 1.6e-02 1.8e-02 1.7e-02
5 LHb mRNA stability Brca2 0.29 0.15 1.0e-03 0.17 0.14 0.16 0.15 9.3e-05 3.5e-04 1.3e-04 1.9e-04
6 Liver gene expression Brca2 0.04 0.03 3.6e-04 0.03 0.02 0.02 0.02 3.5e-04 6.0e-03 2.3e-03 1.4e-03
7 NAcc isoform ratio XM_039089542.2 0.04 0.02 2.8e-04 0.03 0.02 0.03 0.03 2.1e-05 2.7e-04 9.7e-05 6.9e-05
8 RMTg gene expression Brca2 0.26 0.13 7.8e-04 0.13 0.09 0.12 0.12 2.7e-04 2.0e-03 4.2e-04 4.3e-04
9 NAcc mRNA stability Brca2 0.23 0.1 0.0e+00 0.18 0.18 0.18 0.18 1.9e-26 2.3e-26 4.3e-27 3.3e-26
10 IC mRNA stability Brca2 0.21 0.1 3.6e-06 0.16 0.12 0.13 0.14 3.1e-07 1.2e-05 4.4e-06 2.7e-06
11 pVTA mRNA stability Brca2 0.19 0.09 2.7e-11 0.16 0.15 0.16 0.16 5.2e-13 2.0e-12 1.6e-12 1.3e-12
12 BLA isoform ratio XM_017598372.3 0.08 0.05 5.8e-03 0.04 0.04 0.04 0.04 2.4e-03 5.5e-03 2.9e-03 3.7e-03
13 Brain mRNA stability Brca2 0.5 0.15 0.0e+00 0.38 0.36 0.36 0.37 1.3e-37 2.5e-34 2.2e-35 1.9e-36
14 OFC gene expression Brca2 0.27 0.15 5.6e-03 0.12 0.05 0.04 0.09 1.0e-03 2.7e-02 5.0e-02 4.6e-03
15 PL mRNA stability Brca2 0.36 0.14 0.0e+00 0.26 0.25 0.26 0.26 1.9e-28 1.8e-27 7.8e-28 5.1e-28
16 BLA gene expression Brca2 0.36 0.14 3.9e-13 0.24 0.25 0.26 0.25 6.8e-13 2.1e-13 4.1e-14 1.8e-13
17 NAcc gene expression Brca2 0.3 0.12 0.0e+00 0.24 0.25 0.25 0.25 3.3e-36 8.2e-37 8.4e-38 3.5e-37
18 IC gene expression Brca2 0.36 0.13 1.0e-11 0.25 0.25 0.26 0.26 1.0e-10 7.5e-11 1.8e-11 4.1e-11
19 Adipose gene expression Brca2 0.24 0.11 2.7e-14 0.03 0.09 0.09 0.08 4.7e-04 3.7e-10 4.1e-10 3.7e-09
20 NAcc isoform ratio XM_017598372.3 0.02 0.02 5.5e-03 0 0.01 0.01 0 3.4e-01 3.6e-02 1.9e-02 1.0e-01
21 Brain gene expression Brca2 0.45 0.15 0.0e+00 0.32 0.32 0.33 0.33 1.4e-30 5.6e-30 3.0e-31 7.9e-32
22 pVTA gene expression Brca2 0.24 0.11 4.4e-14 0.15 0.16 0.18 0.16 4.0e-12 3.2e-13 1.8e-14 2.8e-13
23 PL gene expression Brca2 0.4 0.14 0.0e+00 0.29 0.29 0.29 0.3 1.4e-31 1.8e-31 2.7e-32 9.0e-33

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density3.15.48.22.92.82.52.52.52.5-2.52.52.52.32.32.32.32.32.32.52.42.22.71.12.11.31.2
Area under the delay curve1.72.05.6-1.6-1.4-0.9-0.9-0.9-0.90.9-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.5-1.4-1.5-2.4-0.2-2.3-1.9-2.2
BMI with tail1.34.49.92.62.53.23.23.23.2-3.21.81.91.92.01.91.91.91.91.61.51.01.10.50.7-1.2-1.0
BMI without tail3.29.617.33.53.54.24.24.24.2-4.23.13.23.23.33.23.23.23.22.72.72.11.32.1-0.2-0.8-1.5
Body weight11.449.884.88.18.29.29.29.29.2-9.27.47.57.47.47.47.47.47.46.56.35.13.94.70.4-1.0-2.5
Weight adjusted by age0.40.71.41.00.90.70.70.70.7-0.71.00.80.70.70.70.70.70.70.90.90.81.20.31.20.70.9
Bone surface3.15.78.92.92.93.03.03.03.0-3.02.72.62.42.42.42.42.42.42.32.21.82.01.31.10.2-0.1
Bone volume1.52.74.62.22.12.12.12.12.1-2.11.81.71.51.51.51.51.51.51.61.41.21.70.41.50.30.3
Breakpoint value in progressive ratio session0.20.21.6-0.2-0.10.10.10.10.1-0.10.10.10.10.10.10.10.10.1-0.2-0.1-0.1-0.80.6-1.3-0.6-1.1
Number of licking bursts1.01.62.61.41.41.11.11.11.1-1.11.31.31.21.21.41.41.41.41.51.41.41.60.71.21.31.2
Context. condit. distance diff. score2.83.35.51.71.91.81.81.81.8-1.82.12.12.12.12.22.22.22.21.81.91.70.62.3-0.90.1-0.9
Locomotion velocity, session 10.70.71.3-1.1-1.0-0.9-0.9-0.9-0.90.9-0.7-0.7-0.9-0.9-0.8-0.8-0.8-0.8-0.9-0.9-0.7-1.0-0.2-1.0-0.3-0.7
Locomotion distance, session 11.41.83.5-1.6-1.6-1.9-1.9-1.9-1.91.9-1.2-1.2-1.3-1.3-1.4-1.4-1.4-1.4-1.2-1.1-0.9-1.0-0.5-0.60.10.0
Locomotion velocity, session 20.20.20.6-0.7-0.6-0.6-0.6-0.6-0.60.6-0.3-0.3-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.3-0.70.2-0.8-0.0-0.4
Locomotion distance, session 21.01.33.8-1.4-1.3-2.0-2.0-2.0-2.02.0-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.6-0.5-0.0-0.40.4-0.51.20.8
Locomotion velocity, session 30.20.20.40.30.40.40.40.40.4-0.40.40.40.50.40.50.50.50.50.30.40.3-0.10.6-0.6-0.1-0.5
Locomotion distance, session 30.20.21.00.20.2-0.1-0.1-0.1-0.10.10.10.10.30.30.40.40.40.40.40.40.60.70.20.71.01.0
Stereotopy head waving bouts, day 32.42.84.42.02.01.81.81.81.8-1.82.12.01.71.71.61.61.61.61.91.81.61.71.11.10.70.5
Stereotopy head waving duration, day 30.00.10.30.10.00.10.10.10.1-0.10.10.0-0.2-0.2-0.4-0.4-0.4-0.4-0.1-0.2-0.20.2-0.50.5-0.10.1
Locomotion velocity, session 71.51.74.2-1.5-1.3-0.9-0.9-0.9-0.90.9-1.0-1.0-1.2-1.2-1.2-1.2-1.2-1.2-1.4-1.4-1.5-2.1-0.3-2.0-1.6-1.7
Locomotion distance, session 70.40.42.5-0.9-0.7-0.8-0.8-0.8-0.80.8-0.2-0.3-0.4-0.4-0.2-0.2-0.2-0.2-0.4-0.4-0.2-1.00.7-1.6-0.1-0.7
Stereotopy head waving bouts, day 70.20.20.6-0.6-0.6-0.8-0.8-0.8-0.80.8-0.4-0.4-0.3-0.3-0.4-0.4-0.4-0.4-0.4-0.3-0.2-0.40.1-0.30.20.1
Stereotopy head waving duration, day 70.50.60.9-0.9-0.9-0.9-0.9-0.9-0.90.9-0.9-0.9-0.7-0.7-0.8-0.8-0.8-0.8-0.8-0.7-0.6-0.7-0.4-0.3-0.2-0.1
Locomotion velocity, session 80.10.11.2-0.00.10.10.10.10.1-0.10.20.20.10.20.10.10.10.1-0.1-0.0-0.1-0.60.5-0.8-0.7-1.1
Locomotion distance, session 80.71.12.30.91.00.90.90.90.9-0.91.21.21.21.21.31.31.31.31.01.00.90.11.5-0.9-0.1-0.8
Degree of sensitization distance1.21.22.3-1.4-1.3-1.2-1.2-1.2-1.21.2-0.9-0.9-1.1-1.0-1.0-1.0-1.0-1.0-1.1-1.1-1.0-1.5-0.1-1.5-0.6-0.9
Degree of sensitization stereotypy0.50.50.9-0.9-0.9-0.8-0.8-0.8-0.80.8-0.8-0.9-0.7-0.7-0.7-0.7-0.7-0.7-0.8-0.7-0.6-0.8-0.3-0.6-0.3-0.3
Conditioned locomotion0.10.11.00.30.20.20.20.20.2-0.20.10.10.10.10.10.10.10.10.20.10.10.6-0.41.00.30.6
Cocaine response after cond. corrected0.70.93.30.50.31.31.31.31.3-1.3-0.6-0.5-0.4-0.4-0.2-0.2-0.2-0.2-0.6-0.8-1.2-0.2-1.80.9-1.8-0.8
Cocaine response after cond. not corrected0.60.73.50.20.11.11.11.11.1-1.1-0.5-0.5-0.4-0.4-0.2-0.2-0.2-0.2-0.6-0.8-1.1-0.6-1.30.2-1.9-1.2
Cocaine response before conditioning0.30.32.5-0.3-0.2-0.5-0.5-0.5-0.50.50.40.40.40.40.30.30.30.30.20.40.5-0.51.4-1.60.4-0.4
Saline control response4.25.69.82.22.31.41.41.41.4-1.42.82.82.82.82.72.72.72.72.93.03.12.32.90.52.51.4
Bone: connectivity density5.28.111.33.43.33.13.13.13.1-3.13.33.33.03.03.03.03.03.03.13.02.72.72.01.41.30.7
Bone: cortical apparent density0.50.61.5-0.8-0.8-0.4-0.4-0.4-0.40.4-0.9-0.8-0.7-0.7-0.7-0.7-0.7-0.7-1.0-0.9-1.0-1.2-0.5-1.1-1.1-1.1
Bone: cortical area1.11.72.91.11.31.61.61.61.6-1.61.51.41.31.31.21.21.21.20.90.90.6-0.31.4-1.4-0.9-1.7
Bone: cortical porosity0.10.10.40.40.4-0.0-0.0-0.0-0.00.00.30.30.40.40.30.30.30.30.50.50.50.60.30.50.50.6
Bone: cortical porosity0.10.10.4-0.3-0.3-0.6-0.6-0.6-0.60.6-0.1-0.1-0.1-0.0-0.2-0.2-0.2-0.2-0.00.00.20.10.2-0.00.50.4
Bone: cortical thickness1.01.62.51.21.31.61.61.61.6-1.61.51.41.31.31.31.31.31.31.01.00.7-0.01.3-1.1-0.7-1.4
Bone: cortical thickness1.21.42.71.11.21.01.01.01.0-1.01.41.41.41.41.41.41.41.41.21.31.20.51.6-0.80.3-0.4
Bone: cortical tissue density0.50.61.3-0.8-0.8-0.4-0.4-0.4-0.40.4-0.9-0.9-0.8-0.7-0.7-0.7-0.7-0.7-1.0-0.9-1.0-1.2-0.6-1.0-1.0-1.0
Condit. Reinf. active minus inactive responses0.60.71.4-0.9-0.9-0.6-0.6-0.6-0.60.6-1.2-1.1-0.7-0.8-0.7-0.7-0.7-0.7-1.0-0.9-1.0-1.2-0.6-0.7-1.0-0.8
Condit. Reinf. active-inactive response ratio0.50.51.8-0.7-0.6-0.3-0.3-0.3-0.30.3-0.9-0.8-0.5-0.6-0.5-0.5-0.5-0.5-0.9-0.8-0.9-1.2-0.4-0.8-1.3-1.2
Condit. Reinf. active responses0.30.30.8-0.8-0.7-0.8-0.8-0.8-0.80.8-0.7-0.7-0.3-0.3-0.3-0.3-0.3-0.3-0.5-0.4-0.3-0.70.2-0.9-0.1-0.3
Condit. Reinf. inactive responses0.50.61.8-0.9-0.8-1.3-1.3-1.3-1.31.3-0.4-0.4-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.10.2-0.30.6-0.81.00.5
Incentive salience index mean0.30.40.9-0.8-0.8-0.8-0.8-0.8-0.80.8-0.9-0.8-0.5-0.5-0.4-0.4-0.4-0.4-0.7-0.6-0.5-0.8-0.1-0.7-0.2-0.3
Condit. Reinf. lever presses0.20.30.7-0.7-0.7-0.9-0.9-0.9-0.90.9-0.6-0.5-0.4-0.4-0.3-0.3-0.3-0.3-0.4-0.3-0.1-0.40.1-0.70.40.1
Condit. Reinf. active minus inactive responses0.91.13.70.50.80.80.80.80.8-0.81.31.31.21.21.11.11.11.10.91.00.9-0.31.9-1.7-0.1-1.2
Condit. Reinf. active-inactive response ratio0.40.52.70.00.20.20.20.20.2-0.20.70.70.60.70.60.60.60.60.40.50.5-0.61.4-1.6-0.2-1.1
Condit. Reinf. active responses0.91.34.60.60.80.80.80.80.8-0.81.41.41.31.31.21.21.21.20.91.11.0-0.32.1-1.8-0.0-1.3
Condit. Reinf. inactive responses0.30.31.00.50.50.40.40.40.4-0.40.80.70.70.70.60.60.60.60.70.70.70.31.0-0.40.3-0.1
Condit. Reinf. lever presses0.10.11.0-0.2-0.1-0.1-0.1-0.1-0.10.10.30.20.20.20.10.10.10.10.00.10.2-0.50.7-1.0-0.0-0.6
Condit. Reinf. lever reinforcers received0.60.83.90.20.40.30.30.30.3-0.31.11.00.91.00.90.90.90.90.70.80.8-0.52.0-1.90.0-1.2
Conditioned reinforcement - actives2.84.76.42.32.32.12.12.12.1-2.12.42.52.52.52.52.52.52.52.42.42.31.62.30.11.00.2
Conditioned reinforcement - inactives0.71.02.01.01.00.60.60.60.6-0.60.90.91.01.01.01.01.01.01.21.21.21.40.71.11.31.3
Conditioned locomotion2.93.75.21.92.01.91.91.91.9-1.92.22.22.32.32.22.22.22.22.12.12.11.22.3-0.40.8-0.1
Patch foraging indifference point 0 sec0.40.84.90.70.50.00.00.00.0-0.00.40.30.30.30.30.30.30.30.70.70.81.8-0.42.21.62.1
Patch foraging indifference point AUC1.31.92.71.51.51.11.11.11.1-1.11.61.61.61.61.51.51.51.51.61.61.61.51.20.61.10.8
Delay disc. indifference point, 0s delay1.71.912.3-0.2-0.11.01.01.01.0-1.0-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-1.0-1.1-1.6-2.2-0.7-2.0-3.5-3.2
Delay disc. indifference point, 16s delay0.40.51.6-0.9-0.8-0.7-0.7-0.7-0.70.7-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.7-0.6-0.5-1.10.3-1.3-0.5-0.9
Delay disc. indifference point, 2s delay4.14.610.9-2.3-2.1-1.4-1.4-1.4-1.41.4-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.9-2.5-2.4-2.6-3.3-1.1-2.7-3.0-3.0
Delay disc. indifference point, 24s delay0.80.91.5-1.2-1.1-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-1.0-1.0-0.9-1.2-0.3-1.0-0.8-0.8
Delay disc. indifference point, 4s delay1.81.95.1-1.4-1.3-0.7-0.7-0.7-0.70.7-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.6-1.6-1.7-2.3-0.7-1.9-2.2-2.2
Delay disc. indifference point, 8s delay0.40.51.9-1.0-0.8-0.8-0.8-0.8-0.80.8-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.6-0.5-0.4-1.10.4-1.4-0.3-0.9
Indifference point function ln k0.10.31.50.00.1-0.3-0.3-0.3-0.30.30.30.30.30.30.40.40.40.40.50.50.70.60.70.31.20.9
Indifference point function log k0.10.31.50.00.1-0.3-0.3-0.3-0.30.30.30.30.30.30.40.40.40.40.50.50.70.60.70.31.20.9
Patch foraging total patch changes 0 sec0.61.16.60.80.6-0.1-0.1-0.1-0.10.10.40.30.40.40.30.30.30.30.90.81.02.1-0.42.52.02.6
Patch foraging total patch changes 12 sec0.50.72.31.00.90.70.70.70.7-0.70.70.70.60.60.50.50.50.50.90.70.71.5-0.21.50.91.2
Patch foraging total patch changes 18 sec0.81.25.61.11.00.50.50.50.5-0.50.70.70.60.70.60.60.60.61.11.01.02.1-0.22.41.62.1
Patch foraging total patch changes 24 sec0.81.47.10.60.6-0.4-0.4-0.4-0.40.40.90.80.70.70.60.60.60.61.21.21.62.00.81.52.72.5
Patch foraging total patch changes 6 sec1.01.55.01.31.10.50.50.50.5-0.51.00.91.01.00.90.90.90.91.41.31.42.20.22.21.92.2
Patch foraging time to switch 0 sec3.06.118.7-1.7-1.8-0.2-0.2-0.2-0.20.2-2.6-2.5-2.5-2.5-2.5-2.5-2.5-2.5-3.0-3.2-3.7-3.0-3.3-0.9-4.3-3.1
Patch foraging water rate 0 sec3.87.916.82.62.61.21.21.21.2-1.23.02.92.92.93.03.03.03.03.53.53.83.72.82.04.13.3
Patch foraging water rate 12 sec0.61.24.80.60.7-0.1-0.1-0.1-0.10.11.11.11.00.91.11.11.11.11.41.41.71.41.60.32.21.6
Patch foraging water rate 18 sec0.30.52.3-0.5-0.3-0.9-0.9-0.9-0.90.90.30.30.30.30.30.30.30.30.40.50.8-0.01.5-0.91.30.5
Patch foraging water rate 24 sec2.94.06.61.92.01.31.31.31.3-1.32.22.32.22.22.32.32.32.32.42.42.62.12.40.72.21.3
Patch foraging water rate 6 sec0.91.33.60.80.90.30.30.30.3-0.31.21.21.11.11.21.21.21.21.41.41.61.41.40.61.91.3
Seeking ratio, delayed vs. immediate footshock1.51.83.7-1.0-1.2-1.5-1.5-1.5-1.51.5-1.4-1.4-1.5-1.4-1.5-1.5-1.5-1.5-1.0-1.1-1.00.1-1.91.40.21.3
Distance traveled before self-admin0.50.71.5-1.0-0.9-0.7-0.7-0.7-0.70.7-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-1.0-0.9-0.9-1.2-0.4-1.0-0.8-0.9
Distance traveled after self-admin0.20.20.6-0.5-0.4-0.7-0.7-0.7-0.70.7-0.00.00.00.00.00.00.00.00.10.20.4-0.10.7-0.60.80.3
Extensor digitorum longus weight4.919.225.14.74.94.94.94.94.9-4.95.05.05.05.04.94.94.94.94.54.54.02.64.2-0.20.6-1.0
Bone: elastic displacement0.40.40.60.70.70.50.50.50.5-0.50.70.70.70.80.80.80.80.80.80.70.70.70.60.30.50.3
Bone: elastic work3.74.86.32.52.52.32.32.32.3-2.32.52.52.42.42.52.52.52.52.42.32.21.91.90.60.90.3
Bone: endosteal estimation1.02.24.11.71.61.01.01.01.0-1.01.81.71.51.51.51.51.51.51.81.71.72.01.11.41.61.5
Bone: endosteal perimeter0.71.52.61.11.20.80.80.80.8-0.81.61.61.41.41.31.31.31.31.51.51.51.11.60.21.10.5
Epididymis fat weight0.00.00.2-0.00.0-0.1-0.1-0.1-0.10.10.20.20.20.20.10.10.10.10.10.20.3-0.00.4-0.30.30.0
Delta time in closed arm before/after self-admin0.30.31.10.20.40.50.50.50.5-0.50.60.60.50.50.50.50.50.50.30.40.3-0.40.9-1.0-0.5-0.9
Delta time in open arm before/after self-admin3.63.64.9-2.1-2.1-2.2-2.2-2.2-2.22.2-2.1-2.1-2.1-2.1-2.1-2.1-2.1-2.1-1.9-1.9-1.6-1.1-1.7-0.0-0.10.4
Diff in mean of infusions in LGA sessions0.20.20.50.30.40.20.20.20.2-0.20.50.50.50.50.50.50.50.50.50.50.60.40.70.00.70.3
Delay discount exponential model param2.22.46.31.91.71.31.31.31.3-1.31.31.31.31.31.31.31.31.31.71.61.62.50.22.41.82.2
Extinction: sum of active levers before priming0.40.40.7-0.8-0.8-0.7-0.7-0.7-0.70.7-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.7-0.6-0.6-0.8-0.2-0.8-0.4-0.4
Active lever presses in extinction session 60.10.10.20.30.30.10.10.10.1-0.10.40.30.30.30.30.30.30.30.40.40.40.50.30.30.50.5
Bone: final force2.13.44.82.02.12.22.22.22.2-2.22.22.12.01.92.02.02.02.01.81.81.50.91.8-0.2-0.1-0.7
Bone: final moment1.52.53.71.71.81.81.81.81.8-1.81.91.81.71.71.71.71.71.71.61.51.30.81.5-0.1-0.0-0.6
Food consumed during 24 hour testing period0.60.92.71.10.90.70.70.70.7-0.70.70.70.70.70.80.80.80.81.00.90.91.50.01.71.01.4
Glucose2.53.95.1-2.3-2.2-2.0-2.0-2.0-2.02.0-1.8-2.0-2.3-2.2-2.2-2.2-2.2-2.2-2.2-2.2-2.1-2.0-1.3-1.0-1.3-1.0
Heart weight0.60.93.30.50.70.30.30.30.3-0.30.91.11.11.11.11.11.11.11.11.21.30.41.8-0.81.10.1
Delay discount hyperbolic model param2.12.36.11.81.61.11.11.11.1-1.11.31.21.31.31.31.31.31.31.71.61.62.50.22.41.92.2
Intermittent access intake day 1-15 change1.02.03.71.61.51.01.01.01.0-1.01.41.41.41.51.41.41.41.41.71.61.71.90.91.41.61.5
Intermittent access intake escalation0.91.83.41.51.51.01.01.01.0-1.01.31.41.41.41.41.41.41.41.61.51.61.80.81.41.41.3
Intermittent access intake escalation 20.20.21.40.30.2-0.1-0.1-0.1-0.10.10.10.20.20.20.20.20.20.20.40.40.50.9-0.01.01.01.2
Intermitt. access day 1 inactive lever presses0.20.61.60.80.80.50.50.50.5-0.50.60.60.70.70.70.70.70.70.90.80.91.30.21.21.01.2
Intermitt. access day 15 inactive lever presses0.40.73.70.0-0.20.40.40.40.4-0.4-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.9-1.0-1.2-0.2-1.91.1-1.4-0.4
Intermitt. access escalation Index0.10.10.5-0.5-0.5-0.5-0.5-0.5-0.50.5-0.2-0.2-0.2-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.1-0.50.3-0.70.1-0.2
Intermittent access day 1 total infusions0.20.41.5-0.9-0.8-0.8-0.8-0.8-0.80.8-0.4-0.4-0.4-0.3-0.4-0.4-0.4-0.4-0.5-0.3-0.2-0.90.5-1.20.0-0.4
Intermittent access day 15 total infusions0.20.31.00.20.3-0.0-0.0-0.0-0.00.00.50.60.60.70.60.60.60.60.60.70.80.41.0-0.30.90.4
Intermittent access terminal intake (last 3 days)0.00.10.3-0.1-0.0-0.2-0.2-0.2-0.20.20.10.20.20.30.20.20.20.20.20.20.30.00.5-0.30.40.1
Intermittent access total infusions0.20.21.3-0.5-0.4-0.2-0.2-0.2-0.20.2-0.2-0.2-0.2-0.1-0.2-0.2-0.2-0.2-0.4-0.3-0.3-0.80.3-1.1-0.5-0.8
Intermittent access day 1 locomotion0.50.72.1-1.1-1.0-0.8-0.8-0.8-0.80.8-0.7-0.7-0.7-0.6-0.7-0.7-0.7-0.7-0.9-0.7-0.7-1.30.1-1.4-0.6-0.9
Intermittent access day 15 total locomotion0.40.82.60.50.60.10.10.10.1-0.11.01.01.01.11.01.01.01.01.11.21.30.61.6-0.51.20.5
Intermittent access total locomotion0.20.21.4-0.6-0.5-0.5-0.5-0.5-0.50.5-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.2-0.1-0.0-0.70.6-1.2-0.0-0.5
Intermittent access standard deviation0.20.42.40.80.60.70.70.70.7-0.70.00.10.10.20.00.00.00.00.20.1-0.10.9-1.01.6-0.20.5
Left kidney weight8.640.259.27.47.47.77.77.77.7-7.76.86.86.86.86.86.86.86.86.46.25.34.74.21.60.8-0.4
Right kidney weight6.931.549.66.66.67.07.07.07.0-7.05.96.05.96.05.95.95.95.95.55.34.54.03.51.40.2-0.7
Cocaine induced anxiety0.20.31.3-0.6-0.5-0.3-0.3-0.3-0.30.3-0.4-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.6-0.5-0.5-1.00.1-1.2-0.7-1.0
Post-drug Anxiety5.76.111.7-2.4-2.4-1.2-1.2-1.2-1.21.2-2.6-2.6-2.5-2.6-2.6-2.6-2.6-2.6-3.1-3.0-3.2-3.4-2.0-2.2-3.3-3.0
Baseline Anxiety4.45.09.5-2.0-2.1-1.0-1.0-1.0-1.01.0-2.5-2.5-2.5-2.5-2.5-2.5-2.5-2.5-2.8-2.9-3.1-2.6-2.6-1.0-2.8-2.1
Tail length7.830.541.95.96.26.56.56.56.5-6.56.16.16.16.06.26.26.26.25.45.44.83.14.9-0.40.5-1.4
Length with tail15.667.897.59.19.49.99.99.99.9-9.99.09.09.09.09.09.09.09.08.18.07.04.96.70.10.6-2.0
Length without tail10.232.750.56.86.87.17.17.17.1-7.16.06.06.16.16.06.06.06.05.65.44.64.23.51.70.5-0.5
Times rat made contact with spout0.91.01.40.91.01.11.11.11.1-1.11.21.11.11.11.21.21.21.21.01.00.90.41.1-0.30.1-0.4
Lifetime Intake0.30.41.1-0.7-0.7-0.4-0.4-0.4-0.40.4-0.6-0.6-0.5-0.5-0.6-0.6-0.6-0.6-0.7-0.7-0.7-1.0-0.2-1.0-0.8-0.9
Liver weight, left4.47.312.63.33.12.62.62.62.6-2.62.82.72.72.72.72.72.72.73.12.92.83.61.22.72.12.3
Liver weight, right2.64.57.82.62.52.82.82.82.8-2.82.12.12.22.22.22.22.22.22.01.91.61.71.00.90.0-0.1
Locomotor activity2.53.910.91.51.71.11.11.11.1-1.12.52.42.42.32.32.32.32.32.32.42.51.03.3-1.11.6-0.1
Locomotor testing distance1.01.83.11.21.30.70.70.70.7-0.71.61.51.51.41.51.51.51.51.61.71.81.41.60.51.61.0
Locomotor testing rearing0.10.31.80.20.1-0.3-0.3-0.3-0.30.30.10.10.0-0.00.00.00.00.00.30.30.40.9-0.11.21.21.3
Locomotion in novel chamber1.92.43.41.61.61.31.31.31.3-1.31.61.71.81.71.71.71.71.71.81.81.81.41.70.11.30.6
Locomotion in novel chamber post-restriction1.82.97.11.41.61.01.01.01.0-1.02.02.02.12.11.91.91.91.92.02.12.31.22.7-0.51.60.3
Fecal boli incidents, locomotor time 11.42.03.51.31.41.31.31.31.3-1.31.61.61.61.61.61.61.61.61.51.61.50.81.9-0.50.7-0.3
Change in fecal boli incidents, locomotor task0.30.31.2-0.3-0.3-0.1-0.1-0.1-0.10.1-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.7-0.8-0.3-1.10.3-0.9-0.2
Time >=10cm from walls, locomotor time 12.72.94.7-1.8-1.8-1.3-1.3-1.3-1.31.3-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.7-2.0-2.0-2.0-2.2-1.3-1.5-2.0-1.6
Bouts of movement, locomotor time 11.72.02.51.51.51.41.41.41.4-1.41.61.61.61.61.61.61.61.61.51.51.51.11.5-0.00.80.1
Total resting periods, locomotor time 11.61.72.31.31.41.31.31.31.3-1.31.51.51.51.51.51.51.51.51.41.51.40.91.5-0.20.7-0.0
Rest time, locomotor task time 11.21.42.31.31.41.51.51.51.5-1.51.31.31.31.31.31.31.31.31.11.10.90.60.9-0.1-0.1-0.4
Distance moved, locomotor task time 10.40.61.2-1.0-0.9-1.1-1.1-1.1-1.11.1-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.6-0.4-0.70.1-0.70.1-0.2
Vertical activity count, locomotor time 10.10.31.5-0.00.1-0.3-0.3-0.3-0.30.30.40.40.40.40.40.40.40.40.50.60.80.21.2-0.51.10.3
Time >=10cm from walls, locomotor time 20.50.74.70.10.10.80.80.80.8-0.8-0.0-0.0-0.0-0.0-0.0-0.0-0.0-0.0-0.5-0.5-0.9-1.2-0.3-1.1-2.2-2.0
Bouts of movement, locomotor time 20.91.51.91.31.31.21.21.21.2-1.21.41.41.41.41.41.41.41.41.31.41.30.91.30.00.70.1
Total resting periods, locomotor time 20.81.41.71.31.31.21.21.21.2-1.21.31.31.31.31.31.31.31.31.31.31.21.01.00.30.60.2
Rest time, locomotor task time 20.20.20.3-0.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.2-0.3-0.1
Distance moved, locomotor task time 20.20.20.40.50.50.30.30.30.3-0.30.50.50.50.50.50.50.50.50.60.60.60.60.50.40.70.5
Vertical activity count, locomotor time 22.12.94.11.81.81.51.51.51.5-1.51.91.91.91.91.91.91.91.92.02.02.01.71.80.71.60.9
Light reinforcement 11.02.54.4-2.0-1.8-1.6-1.6-1.6-1.61.6-1.4-1.4-1.6-1.6-1.5-1.5-1.5-1.5-1.7-1.6-1.5-2.1-0.3-2.0-1.1-1.3
Light reinforcement 20.20.30.5-0.5-0.5-0.6-0.6-0.6-0.60.6-0.4-0.5-0.6-0.7-0.6-0.6-0.6-0.6-0.5-0.5-0.4-0.1-0.50.30.20.3
Bone: marrow area1.02.24.21.61.61.01.01.01.0-1.01.81.61.41.41.41.41.41.41.81.71.72.11.11.51.71.5
Bone: maximum diameter1.02.02.91.61.71.71.71.71.7-1.71.61.61.51.51.41.41.41.41.41.31.10.91.10.1-0.0-0.4
Bone: maximum force1.62.94.61.81.91.81.81.81.8-1.82.22.11.91.81.91.91.91.91.81.81.61.11.8-0.10.4-0.3
Bone: maximum moment1.32.23.91.61.71.51.51.51.5-1.52.01.91.71.61.61.61.61.61.61.61.51.11.60.10.5-0.1
Mean time between licks in bursts0.81.83.3-1.5-1.5-1.8-1.8-1.8-1.81.8-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.2-1.1-0.9-0.5-0.90.30.40.9
Mean num. licks in bursts0.10.20.6-0.4-0.4-0.2-0.2-0.2-0.20.2-0.4-0.3-0.3-0.3-0.4-0.4-0.4-0.4-0.5-0.4-0.5-0.7-0.0-0.7-0.7-0.8
Cd content in liver0.50.52.2-0.6-0.5-1.1-1.1-1.1-1.11.10.30.30.20.30.20.20.20.20.30.40.7-0.21.5-1.11.20.3
Co content in liver1.61.85.61.41.20.60.60.60.6-0.61.01.01.01.11.21.21.21.21.51.41.52.40.32.32.02.4
Cu content in liver0.20.20.5-0.4-0.4-0.7-0.7-0.7-0.70.7-0.3-0.2-0.5-0.1-0.5-0.5-0.5-0.5-0.2-0.2-0.10.1-0.10.30.50.5
Fe content in liver0.40.52.10.30.50.00.00.00.0-0.01.01.00.70.90.60.60.60.60.80.90.90.21.5-0.80.6-0.1
K content in liver0.20.20.9-0.1-0.10.40.40.40.4-0.4-0.2-0.2-0.3-0.2-0.2-0.2-0.2-0.2-0.4-0.5-0.6-0.6-0.4-0.5-0.9-0.9
Mg content in liver0.50.61.40.90.81.21.21.21.2-1.20.50.50.60.60.80.80.80.80.40.40.20.30.10.2-0.5-0.4
Mn content in liver0.10.20.6-0.2-0.3-0.2-0.2-0.2-0.20.2-0.5-0.5-0.4-0.5-0.4-0.4-0.4-0.4-0.4-0.4-0.40.0-0.80.5-0.10.3
Na content in liver0.80.81.70.90.91.31.31.31.3-1.30.80.80.80.90.90.90.90.90.60.60.40.20.4-0.6-0.5-0.9
Rb content in liver2.73.24.5-2.1-2.1-2.0-2.0-2.0-2.02.0-2.1-2.1-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.8-1.6-1.5-1.2-0.6-0.4-0.0
Se content in liver1.01.16.70.20.31.21.21.21.2-1.20.30.3-0.10.30.10.10.10.1-0.4-0.5-0.8-1.40.0-1.7-2.3-2.6
Sr content in liver0.60.51.50.90.80.50.50.50.5-0.50.70.70.60.70.70.70.70.70.80.70.81.20.11.20.81.0
Zn content in liver4.14.66.62.62.52.12.12.12.1-2.12.32.32.22.52.22.22.22.22.42.32.22.51.31.71.41.2
Bone: minimum diameter0.10.10.3-0.3-0.3-0.5-0.5-0.5-0.50.50.0-0.1-0.3-0.3-0.4-0.4-0.4-0.4-0.1-0.2-0.1-0.0-0.0-0.00.20.2
Time in familiar zone, hab. session 10.40.42.8-0.0-0.2-0.0-0.0-0.0-0.00.0-0.6-0.6-0.6-0.7-0.6-0.6-0.6-0.6-0.4-0.5-0.60.4-1.51.7-0.10.8
Time in novel zone, hab. session 10.40.41.20.40.50.60.60.60.6-0.60.60.60.70.80.70.70.70.70.50.50.5-0.20.9-1.1-0.2-0.8
Total zone transitions, hab. session 11.21.73.4-1.7-1.6-1.8-1.8-1.8-1.81.8-1.2-1.2-1.1-1.1-1.0-1.0-1.0-1.0-1.2-1.0-0.7-1.30.1-1.20.1-0.2
Total locomotion distance, hab. session 10.71.01.8-1.3-1.2-1.1-1.1-1.1-1.11.1-1.0-1.0-1.0-0.9-0.9-0.9-0.9-0.9-1.1-1.0-0.9-1.3-0.2-1.2-0.6-0.8
Locomotion velocity, hab. session 11.72.43.8-2.0-1.9-1.8-1.8-1.8-1.81.8-1.5-1.5-1.5-1.5-1.4-1.4-1.4-1.4-1.6-1.5-1.3-1.8-0.4-1.5-0.6-0.8
Time in familiar zone, hab. session 20.30.31.1-0.1-0.10.30.30.30.3-0.3-0.4-0.4-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.6-0.8-0.4-1.00.3-1.1-0.5
Time in novel zone, hab. session 20.20.20.7-0.6-0.5-0.8-0.8-0.8-0.80.8-0.2-0.2-0.1-0.0-0.1-0.1-0.1-0.1-0.10.00.2-0.20.6-0.60.70.2
Total zone transitions, hab. session 20.20.30.80.40.40.30.30.30.3-0.30.50.60.60.60.70.70.70.70.60.60.70.30.9-0.30.50.1
Total locomotion distance, hab. session 20.10.20.4-0.6-0.5-0.6-0.6-0.6-0.60.6-0.3-0.2-0.3-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.1-0.40.3-0.60.3-0.1
Locomotion velocity, hab. session 20.10.10.4-0.5-0.4-0.6-0.6-0.6-0.60.6-0.2-0.2-0.2-0.2-0.1-0.1-0.1-0.1-0.2-0.10.0-0.30.4-0.50.40.0
Novel to familiar place preference ratio0.00.00.2-0.3-0.2-0.3-0.3-0.3-0.30.3-0.0-0.0-0.00.0-0.1-0.1-0.1-0.1-0.10.00.1-0.20.3-0.50.1-0.1
Novelty place preference0.20.20.4-0.6-0.5-0.6-0.6-0.6-0.60.6-0.3-0.3-0.3-0.2-0.4-0.4-0.4-0.4-0.3-0.3-0.1-0.40.1-0.50.1-0.1
Time in novel zone, NPP test0.10.10.2-0.4-0.3-0.4-0.4-0.4-0.40.4-0.2-0.2-0.1-0.1-0.2-0.2-0.2-0.2-0.2-0.1-0.0-0.30.2-0.50.1-0.2
Total zone transitions, NPP test0.10.10.6-0.00.0-0.1-0.1-0.1-0.10.10.20.30.30.30.30.30.30.30.20.30.4-0.10.8-0.60.3-0.2
Total locomotion distance, NPP test0.30.42.3-0.7-0.6-0.5-0.5-0.5-0.50.5-0.3-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.5-0.4-0.3-1.10.6-1.5-0.5-1.1
Locomotion velocity, NPP test0.20.32.3-0.5-0.4-0.5-0.5-0.5-0.50.5-0.00.00.10.10.20.20.20.2-0.10.00.2-0.81.1-1.50.0-0.8
Intraocular pressure1.72.43.41.61.71.41.41.41.4-1.41.81.81.71.61.81.81.81.81.81.71.71.41.50.21.10.4
Delta distance traveled before/after self-admin0.70.72.70.50.5-0.1-0.1-0.1-0.10.10.70.70.70.70.70.70.70.71.01.01.21.30.80.81.61.5
Delta ambulatory time before/after self-admin0.30.42.0-0.3-0.3-0.9-0.9-0.9-0.90.9-0.2-0.1-0.2-0.2-0.2-0.2-0.2-0.20.20.20.40.70.10.71.21.4
Parametrial fat weight0.30.84.40.30.11.11.11.11.1-1.1-0.6-0.5-0.3-0.4-0.3-0.3-0.3-0.3-0.7-0.8-1.2-0.7-1.3-0.1-2.1-1.4
Pavlov. Cond. lever latency2.32.94.32.12.12.02.02.02.0-2.01.91.91.71.71.71.71.71.71.81.71.51.60.91.00.50.3
Pavlov. Cond. magazine entry latency0.20.20.90.30.40.30.30.30.3-0.30.60.60.50.40.60.60.60.60.40.40.4-0.11.0-0.7-0.0-0.4
Pavlov. Cond. change in total contacts1.31.43.4-1.2-1.1-0.7-0.7-0.7-0.70.7-1.1-1.1-1.0-1.0-1.0-1.0-1.0-1.0-1.4-1.3-1.4-1.8-0.5-1.7-1.7-1.6
Pavlov. Cond. index score0.30.30.9-0.7-0.6-0.5-0.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.4-0.4-0.4-0.4-0.6-0.6-0.6-0.90.0-0.9-0.6-0.7
Pavlov. Cond. latency score0.60.71.5-1.0-1.0-0.8-0.8-0.8-0.80.8-0.8-0.8-0.8-0.8-0.7-0.7-0.7-0.7-0.9-0.9-0.9-1.2-0.1-1.1-0.8-0.8
Pavlov. Cond. lever contacts2.22.63.7-1.9-1.9-1.7-1.7-1.7-1.71.7-1.8-1.8-1.7-1.7-1.6-1.6-1.6-1.6-1.8-1.7-1.6-1.7-1.0-1.0-0.9-0.6
Pavlov. Cond. magazine entry number0.20.21.1-0.1-0.2-0.1-0.1-0.1-0.10.1-0.6-0.6-0.4-0.4-0.5-0.5-0.5-0.5-0.4-0.4-0.40.2-1.11.0-0.00.5
Pavlov. Cond. intertrial magazine entries0.70.91.9-0.9-1.0-1.4-1.4-1.4-1.41.4-0.9-0.9-0.8-0.7-0.9-0.9-0.9-0.9-0.7-0.6-0.4-0.1-0.50.20.60.8
Pavlov. Cond. lever-magazine prob. diff.0.20.30.8-0.6-0.6-0.4-0.4-0.4-0.40.4-0.5-0.5-0.5-0.5-0.4-0.4-0.4-0.4-0.6-0.6-0.7-0.9-0.1-0.8-0.8-0.7
Pavlov. Cond. response bias0.10.10.9-0.1-0.1-0.1-0.1-0.1-0.10.10.20.20.10.10.20.20.20.20.10.10.1-0.40.7-0.9-0.1-0.5
Pavlov. Cond. lever latency0.50.62.51.10.90.90.90.90.9-0.90.40.40.50.40.60.60.60.60.60.50.41.2-0.61.60.31.0
Pavlov. Cond. magazine entry latency2.53.15.8-2.1-2.0-1.6-1.6-1.6-1.61.6-1.6-1.6-1.6-1.6-1.7-1.7-1.7-1.7-1.9-1.8-1.7-2.4-0.5-2.2-1.4-1.7
Pavlov. Cond. change in total contacts0.30.51.9-1.0-0.8-1.1-1.1-1.1-1.11.1-0.1-0.2-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.3-0.1-0.90.8-1.40.3-0.5
Pavlov. Cond. index score1.31.73.7-1.7-1.6-1.6-1.6-1.6-1.61.6-1.0-1.0-1.1-1.0-1.1-1.1-1.1-1.1-1.2-1.1-0.8-1.70.3-1.9-0.4-1.0
Pavlov. Cond. latency score1.31.73.6-1.7-1.5-1.5-1.5-1.5-1.51.5-1.0-1.0-1.1-1.1-1.1-1.1-1.1-1.1-1.3-1.1-1.0-1.70.2-1.9-0.6-1.1
Pavlov. Cond. lever contacts0.60.93.3-1.2-1.1-1.0-1.0-1.0-1.01.0-0.5-0.5-0.6-0.6-0.7-0.7-0.7-0.7-0.8-0.7-0.6-1.50.5-1.8-0.5-1.2
Pavlov. Cond. magazine entry number1.82.33.81.91.81.81.81.81.8-1.81.31.31.41.41.51.51.51.51.51.41.21.80.11.80.61.0
Pavlov. Cond. intertrial magazine entries0.60.91.41.01.00.70.70.70.7-0.71.11.11.11.11.11.11.11.11.11.11.21.01.00.50.90.5
Pavlov. Cond. lever-magazine prob. diff.1.41.94.2-1.8-1.6-1.7-1.7-1.7-1.71.7-1.0-1.0-1.1-1.1-1.2-1.2-1.2-1.2-1.3-1.1-0.9-1.80.4-2.0-0.4-1.1
Pavlov. Cond. response bias1.31.85.1-1.8-1.6-1.7-1.7-1.7-1.71.7-0.9-0.9-1.0-0.9-1.1-1.1-1.1-1.1-1.2-1.0-0.8-1.90.6-2.3-0.4-1.3
Time in closed arm before self-admin2.43.04.81.71.81.21.21.21.2-1.21.91.92.02.02.02.02.02.02.12.12.21.91.90.61.81.2
Time in closed arm after self-admin3.03.26.11.61.71.21.21.21.2-1.22.12.12.12.12.12.12.12.12.12.22.21.42.5-0.21.40.6
Time in open arm before self-admin0.10.11.0-0.3-0.2-0.1-0.1-0.1-0.10.10.10.0-0.0-0.0-0.0-0.0-0.0-0.0-0.2-0.1-0.1-0.70.5-1.0-0.4-0.9
Time in open arm after self-admin1.92.12.7-1.6-1.6-1.4-1.4-1.4-1.41.4-1.7-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.5-1.3-1.4-0.4-0.8-0.3
Bone: periosteal estimation1.22.44.41.71.81.61.61.61.6-1.62.12.01.71.71.71.71.71.71.71.71.51.11.60.10.5-0.1
Bone: periosteal perimeter0.30.52.20.40.60.40.40.40.4-0.41.11.10.90.90.70.70.70.70.70.80.8-0.11.5-1.00.1-0.7
Bone: post-yield work0.20.20.50.40.50.20.20.20.2-0.20.70.60.50.50.40.40.40.40.60.60.70.60.60.30.60.4
Progressive ratio test 1 active lever presses1.11.41.81.21.31.31.31.31.3-1.31.31.31.31.41.31.31.31.31.21.21.10.51.3-0.30.1-0.4
Progressive ratio test 1 breakpoint1.11.31.81.21.21.31.31.31.3-1.31.31.31.31.31.31.31.31.31.11.21.00.51.2-0.40.1-0.5
Progressive ratio test 1 inactive lever presses1.31.92.91.51.41.01.01.01.0-1.01.51.51.51.51.51.51.51.51.71.61.71.71.21.01.51.2
Progressive ratio test 2 active lever presses1.51.83.11.21.31.01.01.01.0-1.01.51.51.61.61.61.61.61.61.61.61.71.01.8-0.11.10.4
Progressive ratio test 2 breakpoint1.41.63.01.21.20.90.90.90.9-0.91.41.51.51.61.51.51.51.51.51.61.61.01.7-0.11.10.4
Progressive ratio test 2 inactive lever presses3.35.47.72.52.51.91.91.91.9-1.92.52.52.62.62.52.52.52.52.72.72.82.62.11.32.11.6
Incentive Sensitization - Responses0.10.10.40.00.0-0.2-0.2-0.2-0.20.20.10.10.20.20.20.20.20.20.20.30.40.30.30.10.60.6
Incentive Sensitization - Breakpoint0.10.10.5-0.1-0.1-0.3-0.3-0.3-0.30.30.00.00.10.10.10.10.10.10.20.20.40.30.30.10.70.6
Sum of active levers in priming session hrs 5-60.40.31.9-0.1-0.10.40.40.40.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.6-0.6-0.9-0.7-0.7-0.2-1.4-1.1
Progressive ratio0.50.81.5-0.8-0.8-0.7-0.7-0.7-0.70.7-1.0-1.0-1.0-1.0-1.2-1.2-1.2-1.2-1.0-1.0-1.1-0.7-1.20.0-0.9-0.2
Food seeking constrained by brief footshock0.91.14.4-0.4-0.6-0.9-0.9-0.9-0.90.9-1.1-1.0-0.9-0.9-0.9-0.9-0.9-0.9-0.5-0.6-0.40.9-1.72.10.92.0
Seeking ratio, punishment vs. effort0.81.11.61.11.00.90.90.90.9-0.90.90.91.01.01.21.21.21.21.11.11.21.30.70.91.10.9
Retroperitoneal fat weight0.41.88.1-0.7-0.70.40.40.40.4-0.4-1.2-1.1-1.0-1.1-1.1-1.1-1.1-1.1-1.5-1.6-2.0-1.9-1.5-1.0-2.9-2.3
Reaction time number correct0.91.84.91.21.10.30.30.30.3-0.31.41.31.31.31.21.21.21.21.61.61.82.01.21.42.21.9
Reaction time mean minus median0.51.210.8-0.9-0.6-0.3-0.3-0.3-0.30.30.10.1-0.00.0-0.1-0.1-0.1-0.1-0.5-0.3-0.4-2.11.5-3.3-1.3-2.6
Reaction time mean minus median AUC0.41.14.9-1.4-1.2-1.3-1.3-1.3-1.31.3-0.4-0.4-0.6-0.5-0.6-0.6-0.6-0.6-0.7-0.5-0.3-1.51.0-2.2-0.1-1.0
Reaction time num false alarms0.30.42.0-0.9-0.7-0.9-0.9-0.9-0.90.9-0.2-0.2-0.2-0.2-0.1-0.1-0.1-0.1-0.3-0.10.1-0.91.0-1.40.2-0.5
Reaction time num false alarms AUC0.10.21.1-0.6-0.4-0.6-0.6-0.6-0.60.60.0-0.0-0.0-0.00.00.00.00.0-0.10.00.2-0.60.9-1.10.3-0.4
Reaction time trials correct on left0.91.84.91.21.10.30.30.30.3-0.31.41.31.31.31.21.21.21.21.61.61.82.01.21.42.21.9
Reaction time trials on left0.91.64.61.11.10.30.30.30.3-0.31.41.31.21.21.21.21.21.21.61.61.81.91.21.32.21.9
Reaction time mean3.25.19.6-2.7-2.5-1.9-1.9-1.9-1.91.9-2.3-2.2-2.2-2.2-2.2-2.2-2.2-2.2-2.6-2.4-2.4-3.1-1.0-2.5-2.1-2.3
Reaction time mean AUC3.25.18.9-2.7-2.6-2.1-2.1-2.1-2.12.1-2.3-2.2-2.2-2.2-2.2-2.2-2.2-2.2-2.5-2.4-2.3-3.0-1.0-2.4-1.9-2.0
Median of all reaction times4.56.48.8-2.9-2.8-2.2-2.2-2.2-2.22.2-2.8-2.7-2.7-2.7-2.7-2.7-2.7-2.7-2.9-2.8-2.8-3.0-1.9-1.7-2.1-1.8
Reaction time omissions0.91.33.1-1.4-1.3-1.0-1.0-1.0-1.01.0-0.9-1.0-1.0-1.0-1.1-1.1-1.1-1.1-1.3-1.2-1.1-1.8-0.2-1.7-1.1-1.4
Reaction time false alarm rate0.50.62.9-1.0-0.9-0.6-0.6-0.6-0.60.6-0.6-0.6-0.5-0.5-0.4-0.4-0.4-0.4-0.8-0.7-0.6-1.50.4-1.7-0.8-1.3
Reaction time premature initiation rate0.20.21.9-0.5-0.3-0.2-0.2-0.2-0.20.2-0.1-0.1-0.1-0.0-0.1-0.1-0.1-0.1-0.3-0.2-0.2-0.90.6-1.4-0.6-1.0
Reaction time premature initiations0.10.21.00.00.1-0.1-0.1-0.1-0.10.10.50.50.40.50.40.40.40.40.40.50.5-0.01.0-0.60.4-0.1
Std. dev. reaction times1.12.18.4-1.7-1.5-1.0-1.0-1.0-1.01.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.5-1.3-1.3-2.50.3-2.9-1.7-2.4
Reaction time trials completed0.91.64.61.11.10.30.30.30.3-0.31.41.31.21.21.21.21.21.21.61.61.81.91.21.32.21.9
Reaction time trials AUC0.71.44.80.90.90.00.00.00.0-0.01.21.11.11.11.01.01.01.01.41.41.71.81.11.22.21.9
Run reversals in cocaine runway, females0.90.91.4-0.9-1.0-1.0-1.0-1.0-1.01.0-1.2-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.0-1.0-0.9-0.5-1.20.3-0.30.3
Run reversals in cocaine runway, males0.50.53.70.10.1-0.6-0.6-0.6-0.60.60.40.40.40.40.40.40.40.40.70.71.10.90.90.41.91.4
Latency to leave start box in cocaine runway0.20.21.0-0.2-0.20.20.20.20.2-0.2-0.5-0.4-0.4-0.4-0.3-0.3-0.3-0.3-0.5-0.5-0.7-0.6-0.6-0.3-1.0-0.7
Latency to leave start box in cocaine runway, F0.30.31.10.50.41.01.01.01.0-1.0-0.10.00.10.10.20.20.20.2-0.0-0.1-0.4-0.1-0.70.3-1.0-0.5
Latency to leave start box in cocaine runway, M0.30.20.5-0.7-0.6-0.7-0.7-0.7-0.70.7-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.2-0.50.1-0.60.1-0.1
Std. dev. time between licks in bursts0.20.31.50.10.3-0.1-0.1-0.1-0.10.10.70.60.60.60.60.60.60.60.60.70.90.21.2-0.50.90.1
Total sessions with >9 infusions0.20.30.9-0.3-0.30.10.10.10.1-0.1-0.6-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.7-0.7-0.8-0.5-0.90.1-0.9-0.5
Short access day 1 total inactive lever presses0.30.41.60.80.70.90.90.90.9-0.90.30.30.30.30.30.30.30.30.40.30.10.8-0.61.3-0.10.4
Short access day 10 total inactive lever presses1.12.86.72.32.02.22.22.22.2-2.21.21.21.31.31.31.31.31.31.41.20.92.1-0.62.60.31.0
Short access day 1 total infusions1.01.32.8-1.0-1.1-0.7-0.7-0.7-0.70.7-1.4-1.4-1.3-1.3-1.4-1.4-1.4-1.4-1.3-1.4-1.4-0.8-1.70.4-1.0-0.2
Short access day 10 total infusions0.30.40.6-0.7-0.7-0.5-0.5-0.5-0.50.5-0.8-0.8-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.5-0.7-0.1-0.4-0.1
Short access total infusions1.21.52.8-1.1-1.1-0.5-0.5-0.5-0.50.5-1.4-1.4-1.4-1.3-1.4-1.4-1.4-1.4-1.5-1.5-1.7-1.3-1.6-0.3-1.6-1.1
Short access day 1 locomotion0.50.62.6-0.9-0.8-0.5-0.5-0.5-0.50.5-0.6-0.6-0.6-0.5-0.6-0.6-0.6-0.6-0.8-0.7-0.7-1.40.1-1.6-1.0-1.3
Short access day 10 total locomotion0.10.10.90.50.40.30.30.30.3-0.30.10.20.20.20.10.10.10.10.30.30.20.7-0.30.90.30.6
Short access total locomotion0.80.91.6-1.0-1.0-0.5-0.5-0.5-0.50.5-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.2-1.1-1.2-1.3-0.8-0.8-1.2-1.0
One hour access (0.3 mA shock)2.73.19.01.21.30.20.20.20.2-0.21.81.81.91.91.81.81.81.82.22.32.62.12.40.73.02.2
Compulsive drug intake1.61.93.3-1.5-1.6-1.8-1.8-1.8-1.81.8-1.4-1.4-1.4-1.5-1.4-1.4-1.4-1.4-1.2-1.2-0.9-0.5-1.00.20.40.8
One hour access (shock baseline)1.82.76.01.41.61.11.11.11.1-1.11.92.02.02.01.91.91.91.91.92.02.01.02.5-0.61.20.2
Social response proportion4.04.66.41.92.12.52.52.52.5-2.52.42.42.32.32.42.42.42.41.81.91.60.22.5-1.6-0.6-1.8
Social responses1.82.45.61.31.51.11.11.11.1-1.11.91.91.81.71.81.81.81.81.71.81.80.92.4-0.81.00.0
Social time2.43.35.6-2.4-2.3-2.3-2.3-2.3-2.32.3-1.8-1.8-1.8-1.9-1.8-1.8-1.8-1.8-1.8-1.7-1.4-1.9-0.4-1.6-0.3-0.5
Soleus weight1.54.46.32.32.32.02.02.02.0-2.02.52.52.32.32.42.42.42.42.42.32.21.81.90.41.10.4
Bone: stiffness0.40.72.50.50.60.50.50.50.5-0.51.11.11.00.90.90.90.90.90.80.90.9-0.01.6-1.00.2-0.6
Tibialis anterior weight5.920.129.04.85.05.45.45.45.4-5.45.15.05.04.94.94.94.94.94.34.33.72.14.0-0.7-0.2-1.9
Time to tail flick, vehicle, before self-admin1.81.84.8-1.3-1.2-0.5-0.5-0.5-0.50.5-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.6-1.6-1.7-2.2-0.9-1.8-2.2-2.2
Time to tail flick, vehicle, after self-admin0.00.10.5-0.2-0.1-0.2-0.2-0.2-0.20.20.10.10.10.10.10.10.10.10.00.10.1-0.30.6-0.70.1-0.3
Time to tail flick, test, before self-admin1.31.41.81.31.31.21.21.21.2-1.21.31.31.31.31.31.31.31.31.31.31.21.11.10.40.70.3
Time to tail flick, test, after self-admin0.50.51.7-0.6-0.6-0.1-0.1-0.1-0.10.1-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.9-0.9-1.0-1.1-0.7-0.6-1.3-1.2
Delta time to tail flick, vehicle, before/after SA0.30.31.8-0.0-0.0-0.6-0.6-0.6-0.60.60.20.20.20.20.20.20.20.20.50.50.70.70.70.41.31.2
Delta time to tail flick, test, before/after SA1.21.21.7-1.1-1.2-1.0-1.0-1.0-1.01.0-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-0.9-1.3-0.0-0.8-0.2
Tibia length3.39.217.03.63.64.14.14.14.1-4.13.23.13.13.03.03.03.03.02.72.51.91.81.50.7-0.8-1.2
Ambulatory time before self-admin0.10.21.1-0.5-0.4-0.3-0.3-0.3-0.30.3-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.4-0.3-0.3-0.80.3-1.0-0.4-0.8
Ambulatory time after self-admin0.30.30.9-0.7-0.6-0.9-0.9-0.9-0.90.9-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.10.1-0.20.4-0.50.70.4
Bone: tissue strength0.40.42.90.60.50.20.20.20.2-0.20.10.10.10.10.20.20.20.20.40.30.31.2-0.71.70.71.4
Total heroin consumption3.43.96.5-2.5-2.4-2.4-2.4-2.4-2.42.4-2.0-1.9-1.9-1.9-1.9-1.9-1.9-1.9-2.0-1.8-1.7-2.2-0.6-1.8-0.8-0.7
Bone: trabecular number3.15.17.22.72.62.62.62.62.6-2.62.42.42.42.42.42.42.42.42.42.32.02.01.31.20.70.4
Bone: trabecular spacing2.93.95.0-2.2-2.2-2.2-2.2-2.2-2.22.2-2.1-2.2-2.2-2.2-2.2-2.2-2.2-2.2-2.0-2.0-1.8-1.3-1.7-0.1-0.40.2
Bone: trabecular thickness3.34.15.72.42.42.32.32.32.3-2.32.22.32.12.22.22.22.22.22.12.01.81.61.40.70.40.0
Bone: trabecular tissue density1.01.511.0-0.8-0.50.20.20.20.2-0.2-0.3-0.2-0.1-0.1-0.0-0.0-0.0-0.0-0.8-0.6-0.8-2.41.0-3.3-2.1-3.1
Water consumed over 24 hours3.24.35.52.32.32.12.12.12.1-2.12.32.22.22.22.32.32.32.32.32.32.22.11.51.11.40.9
Number of responses in last shaping day0.30.30.5-0.5-0.5-0.3-0.3-0.3-0.30.3-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.7-0.6-0.6-0.1-0.6-0.4