Hub : Genes

B3gat3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability B3gat3 0.06 0.05 5.9e-03 0.01 0.02 0 0.01 6.0e-02 9.1e-04 1.8e-01 2.7e-02
2 PL alternative polyA XM_039108583.1 0.06 0.03 3.9e-09 0.09 0.08 0.1 0.09 7.9e-10 3.0e-09 7.9e-11 8.7e-10
3 PL alternative polyA NM_001128184.1 0.06 0.04 2.8e-09 0.09 0.08 0.1 0.09 6.9e-10 2.5e-09 5.8e-11 6.3e-10
4 PL isoform ratio NM_001128184.1 0.01 0.01 9.2e-03 0.01 0.02 0.01 0.01 7.2e-03 5.3e-03 9.7e-03 8.3e-03
5 NAcc gene expression B3gat3 0.02 0.01 4.0e-03 0.02 0.02 0 0.01 2.3e-03 5.3e-03 8.6e-02 1.2e-02
6 Brain alternative polyA NM_001128184.1 0.08 0.06 6.4e-05 0.05 0.04 0.05 0.05 8.5e-06 9.9e-05 3.4e-05 3.1e-05
7 Brain alternative polyA XM_039108583.1 0.08 0.06 6.9e-05 0.05 0.04 0.05 0.05 9.8e-06 1.1e-04 3.2e-05 4.1e-05
8 Brain gene expression B3gat3 0.04 0.03 4.0e-03 0.02 0.01 0.01 0.01 8.6e-03 3.5e-02 3.3e-02 7.5e-02
9 NAcc alternative polyA NM_001128184.1 0.06 0.07 5.7e-06 0.05 0.02 0.04 0.04 1.2e-06 4.0e-03 3.5e-05 3.8e-05
10 NAcc alternative polyA XM_039108583.1 0.06 0.06 1.1e-05 0.05 0.02 0.04 0.04 2.1e-06 4.9e-03 5.6e-05 4.6e-05
11 pVTA alternative polyA NM_001128184.1 0.16 0.1 3.2e-06 0.14 0.07 0.07 0.1 1.3e-06 4.0e-04 4.9e-04 5.0e-05
12 pVTA alternative polyA XM_039108583.1 0.18 0.1 1.3e-06 0.15 0.1 0.09 0.12 4.9e-07 6.8e-05 7.0e-05 7.8e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.40.73.0-0.11.6-1.70.60.4-0.30.30.4-0.60.6-0.60.6
Area under the delay curve0.30.32.2-1.50.7-0.80.20.2-0.30.30.3-0.30.3-0.30.3
BMI with tail1.75.57.8-2.40.1-0.52.82.7-2.62.62.7-2.52.5-2.42.4
BMI without tail1.22.43.1-1.8-1.21.01.61.7-1.81.81.8-1.51.5-1.51.5
Body weight3.012.717.6-1.2-2.42.04.14.2-4.14.14.2-3.83.8-3.73.7
Weight adjusted by age1.11.21.90.8-0.50.31.41.2-1.11.11.2-1.21.2-1.31.3
Bone surface1.11.93.00.91.4-1.71.71.2-1.31.31.2-1.41.4-1.31.3
Bone volume0.61.04.10.91.8-2.01.00.5-0.60.60.5-0.70.7-0.70.7
Breakpoint value in progressive ratio session1.82.04.31.9-2.12.01.51.1-1.11.11.2-1.11.1-1.11.1
Number of licking bursts0.00.00.0-0.20.2-0.2-0.00.0-0.10.1-0.0-0.00.00.1-0.1
Context. condit. distance diff. score0.70.83.0-1.71.6-1.7-0.5-0.40.5-0.5-0.40.3-0.30.2-0.2
Locomotion velocity, session 10.40.42.2-1.50.6-0.70.20.4-0.30.30.4-0.60.6-0.50.5
Locomotion distance, session 10.91.22.9-1.70.8-1.00.91.0-1.01.01.0-1.01.0-1.11.1
Locomotion velocity, session 21.82.23.6-0.2-0.30.11.91.7-1.71.71.7-1.61.6-1.61.6
Locomotion distance, session 20.40.51.6-1.3-0.50.40.70.7-0.70.70.7-0.70.7-0.70.7
Locomotion velocity, session 30.80.93.8-2.01.0-1.20.60.8-0.80.80.8-0.70.7-0.50.5
Locomotion distance, session 30.20.20.4-0.70.4-0.50.20.6-0.60.60.6-0.50.5-0.30.3
Stereotopy head waving bouts, day 30.91.16.0-2.41.6-1.7-0.1-0.50.4-0.4-0.40.3-0.30.4-0.4
Stereotopy head waving duration, day 30.60.75.1-2.31.0-1.1-0.1-0.40.4-0.4-0.40.3-0.30.3-0.3
Locomotion velocity, session 70.30.41.6-0.91.2-1.3-0.1-0.40.3-0.3-0.30.3-0.30.3-0.3
Locomotion distance, session 70.40.54.0-2.01.0-1.1-0.2-0.10.0-0.0-0.0-0.10.1-0.00.0
Stereotopy head waving bouts, day 70.20.31.60.31.1-1.20.3-0.20.2-0.2-0.20.2-0.20.2-0.2
Stereotopy head waving duration, day 71.01.22.50.5-0.50.31.61.3-1.21.21.3-1.21.2-1.21.2
Locomotion velocity, session 80.20.21.9-1.4-0.20.10.00.2-0.10.10.2-0.20.2-0.30.3
Locomotion distance, session 80.71.03.6-1.91.8-1.9-0.3-0.40.5-0.5-0.50.4-0.40.3-0.3
Degree of sensitization distance0.50.53.1-1.81.2-1.2-0.1-0.30.3-0.3-0.30.1-0.10.1-0.1
Degree of sensitization stereotypy0.30.41.61.30.2-0.41.00.5-0.40.40.5-0.40.4-0.50.5
Conditioned locomotion0.60.71.1-0.3-1.10.90.90.8-0.70.70.7-0.90.9-0.90.9
Cocaine response after cond. corrected0.50.64.4-2.10.6-0.6-0.7-0.50.5-0.5-0.50.3-0.30.3-0.3
Cocaine response after cond. not corrected0.40.41.6-1.31.0-0.9-0.7-0.50.4-0.4-0.50.3-0.30.3-0.3
Cocaine response before conditioning0.50.66.02.50.3-0.20.30.3-0.30.30.3-0.10.1-0.10.1
Saline control response2.53.34.80.0-1.31.11.82.2-2.12.12.1-1.91.9-1.91.9
Bone: connectivity density1.21.92.7-0.21.0-1.31.61.4-1.31.31.4-1.61.6-1.61.6
Bone: cortical apparent density0.40.50.80.9-0.20.10.80.7-0.60.60.7-0.80.8-0.80.8
Bone: cortical area0.40.71.10.90.5-0.61.00.9-1.11.10.8-0.70.7-0.70.7
Bone: cortical porosity0.10.20.20.4-0.50.5-0.1-0.40.5-0.5-0.40.3-0.30.4-0.4
Bone: cortical porosity0.20.21.00.3-1.01.00.20.00.1-0.10.0-0.10.1-0.10.1
Bone: cortical thickness3.05.06.90.9-1.91.62.32.5-2.62.62.5-2.32.3-2.32.3
Bone: cortical thickness0.80.91.30.0-0.80.70.81.1-1.11.11.1-1.11.1-1.01.0
Bone: cortical tissue density0.50.60.90.9-0.40.20.90.7-0.70.70.7-0.90.9-0.90.9
Condit. Reinf. active minus inactive responses0.80.91.30.60.0-0.21.11.1-0.90.91.0-1.11.1-1.11.1
Condit. Reinf. active-inactive response ratio0.40.50.80.5-0.40.30.70.7-0.60.60.7-0.90.9-0.90.9
Condit. Reinf. active responses0.50.61.10.80.7-0.91.00.7-0.60.60.7-0.80.8-0.70.7
Condit. Reinf. inactive responses0.40.51.80.51.4-1.3-0.1-0.40.4-0.4-0.40.4-0.40.5-0.5
Incentive salience index mean1.01.21.60.20.3-0.51.31.3-1.21.21.2-1.31.3-1.31.3
Condit. Reinf. lever presses0.60.81.0-0.10.5-0.60.91.0-1.01.01.0-0.90.9-0.90.9
Condit. Reinf. active minus inactive responses0.91.12.01.41.0-0.9-0.7-1.01.0-1.0-1.01.1-1.11.1-1.1
Condit. Reinf. active-inactive response ratio2.22.43.01.01.7-1.7-0.9-1.61.6-1.6-1.61.6-1.61.6-1.6
Condit. Reinf. active responses0.10.10.80.90.6-0.6-0.1-0.00.0-0.00.00.1-0.10.2-0.2
Condit. Reinf. inactive responses0.60.71.1-0.2-0.40.50.31.0-1.01.01.1-0.90.9-0.90.9
Condit. Reinf. lever presses0.50.61.61.3-0.20.10.90.8-0.90.90.8-0.80.8-0.70.7
Condit. Reinf. lever reinforcers received0.10.21.71.30.3-0.30.20.2-0.20.20.2-0.10.1-0.00.0
Conditioned reinforcement - actives2.82.83.51.11.5-1.3-1.6-1.81.9-1.9-1.81.7-1.71.8-1.8
Conditioned reinforcement - inactives1.71.95.10.42.2-2.3-1.0-1.21.2-1.2-1.21.3-1.31.2-1.2
Conditioned locomotion2.53.05.6-0.92.3-2.4-1.5-1.61.8-1.8-1.71.6-1.61.6-1.6
Patch foraging indifference point 0 sec0.40.71.0-0.2-0.40.21.00.9-0.90.90.9-0.90.9-0.80.8
Patch foraging indifference point AUC1.11.35.42.3-0.50.41.60.9-1.01.00.9-1.01.0-1.01.0
Delay disc. indifference point, 0s delay0.80.87.1-2.71.2-1.2-0.3-0.10.0-0.0-0.00.0-0.00.0-0.0
Delay disc. indifference point, 16s delay0.20.21.3-0.21.0-1.10.30.1-0.20.20.2-0.20.2-0.20.2
Delay disc. indifference point, 2s delay0.70.73.2-1.01.8-1.8-0.4-0.50.4-0.4-0.40.4-0.40.4-0.4
Delay disc. indifference point, 24s delay0.60.61.3-1.1-1.01.00.40.7-0.60.60.6-0.60.6-0.60.6
Delay disc. indifference point, 4s delay1.21.25.4-2.30.6-0.80.70.9-1.01.01.0-1.01.0-1.01.0
Delay disc. indifference point, 8s delay0.30.33.3-1.8-0.20.2-0.4-0.10.2-0.2-0.20.2-0.20.2-0.2
Indifference point function ln k2.02.813.7-3.71.6-1.5-2.1-1.21.2-1.2-1.21.0-1.01.2-1.2
Indifference point function log k2.02.813.7-3.71.6-1.5-2.1-1.21.2-1.2-1.21.0-1.01.2-1.2
Patch foraging total patch changes 0 sec0.60.91.2-0.4-0.60.51.01.1-1.11.11.1-1.11.1-1.01.0
Patch foraging total patch changes 12 sec4.05.29.41.6-1.81.53.12.4-2.42.42.3-2.42.4-2.32.3
Patch foraging total patch changes 18 sec0.30.41.41.2-0.50.50.80.4-0.50.50.4-0.50.5-0.50.5
Patch foraging total patch changes 24 sec5.56.710.30.2-1.51.23.22.8-2.92.92.9-2.92.9-2.92.9
Patch foraging total patch changes 6 sec0.91.32.1-0.2-0.2-0.11.41.3-1.21.21.3-1.41.4-1.21.2
Patch foraging time to switch 0 sec0.10.20.70.20.7-0.80.70.2-0.10.10.2-0.20.2-0.30.3
Patch foraging water rate 0 sec0.10.20.7-0.10.2-0.1-0.9-0.40.4-0.4-0.50.3-0.30.4-0.4
Patch foraging water rate 12 sec0.50.83.9-2.00.10.1-1.6-0.60.6-0.6-0.50.7-0.70.6-0.6
Patch foraging water rate 18 sec0.50.77.0-2.60.6-0.5-0.80.1-0.10.10.2-0.10.1-0.20.2
Patch foraging water rate 24 sec0.50.81.7-1.20.7-0.7-1.3-0.80.9-0.9-0.80.7-0.70.7-0.7
Patch foraging water rate 6 sec0.40.63.7-1.9-0.00.2-1.2-0.40.6-0.6-0.40.4-0.40.5-0.5
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.40.3-0.30.10.1-0.30.30.2-0.10.1-0.40.4
Distance traveled before self-admin1.41.52.91.7-0.40.21.51.3-1.31.31.2-1.31.3-1.31.3
Distance traveled after self-admin0.30.32.11.5-0.50.50.40.4-0.40.40.5-0.40.4-0.40.4
Extensor digitorum longus weight5.120.227.90.1-2.31.75.35.2-5.25.25.2-4.94.9-5.05.0
Bone: elastic displacement0.30.31.1-0.4-1.01.0-0.7-0.40.5-0.5-0.40.3-0.30.2-0.2
Bone: elastic work1.31.72.5-0.6-1.61.41.11.3-1.31.31.3-1.41.4-1.41.4
Bone: endosteal estimation1.73.77.7-1.32.8-2.6-1.5-1.81.7-1.7-1.81.8-1.81.8-1.8
Bone: endosteal perimeter3.06.312.5-0.43.5-3.3-2.0-2.42.3-2.3-2.42.5-2.52.5-2.5
Epididymis fat weight0.30.72.4-1.50.5-0.3-0.9-0.50.4-0.4-0.40.9-0.91.0-1.0
Delta time in closed arm before/after self-admin3.43.37.5-2.7-1.41.21.41.8-1.81.81.8-1.81.8-1.81.8
Delta time in open arm before/after self-admin0.80.74.32.10.1-0.21.20.6-0.50.50.7-0.70.7-0.60.6
Diff in mean of infusions in LGA sessions1.61.82.21.3-1.51.41.41.2-1.21.21.4-1.41.4-1.21.2
Delay discount exponential model param0.30.32.11.5-0.60.7-0.2-0.20.3-0.3-0.30.3-0.30.3-0.3
Extinction: sum of active levers before priming2.82.74.11.2-0.50.32.01.8-1.71.71.9-2.02.0-1.81.8
Active lever presses in extinction session 61.81.76.22.5-0.90.71.61.2-1.01.01.2-1.31.3-1.21.2
Bone: final force1.32.13.30.30.6-0.91.81.6-1.61.61.6-1.61.6-1.61.6
Bone: final moment1.22.03.10.40.4-0.71.81.6-1.61.61.6-1.61.6-1.61.6
Food consumed during 24 hour testing period0.20.21.31.10.2-0.1-0.4-0.40.3-0.3-0.40.4-0.40.4-0.4
Glucose2.43.74.6-1.31.6-1.4-2.1-2.02.0-2.0-2.02.1-2.12.1-2.1
Heart weight0.71.06.4-2.5-0.20.4-1.0-0.80.7-0.7-0.70.7-0.70.8-0.8
Delay discount hyperbolic model param0.40.42.31.5-0.80.9-0.2-0.30.3-0.3-0.30.3-0.30.3-0.3
Intermittent access intake day 1-15 change2.01.94.32.10.20.1-1.3-1.61.4-1.4-1.41.4-1.41.6-1.6
Intermittent access intake escalation1.31.33.71.90.20.0-1.0-1.31.1-1.1-1.11.1-1.11.3-1.3
Intermittent access intake escalation 20.50.54.52.1-0.10.3-0.2-0.50.4-0.4-0.40.4-0.40.5-0.5
Intermitt. access day 1 inactive lever presses2.42.65.3-0.42.3-2.2-1.5-1.51.5-1.5-1.51.6-1.61.5-1.5
Intermitt. access day 15 inactive lever presses0.50.63.50.21.8-1.90.1-0.0-0.10.1-0.00.1-0.10.0-0.0
Intermitt. access escalation Index0.40.43.0-1.70.8-0.8-0.3-0.10.1-0.1-0.10.0-0.00.1-0.1
Intermittent access day 1 total infusions2.52.811.3-2.43.1-3.4-0.8-0.90.9-0.9-1.00.9-0.90.9-0.9
Intermittent access day 15 total infusions4.34.88.2-0.22.9-2.8-2.0-2.22.2-2.2-2.22.1-2.12.2-2.2
Intermittent access terminal intake (last 3 days)2.02.17.9-0.02.7-2.8-0.8-1.21.1-1.1-1.11.1-1.11.2-1.2
Intermittent access total infusions2.02.27.3-0.72.6-2.7-0.9-1.21.2-1.2-1.21.2-1.21.2-1.2
Intermittent access day 1 locomotion2.12.29.7-3.02.8-3.1-0.1-0.20.2-0.2-0.30.1-0.10.2-0.2
Intermittent access day 15 total locomotion0.91.04.7-0.62.0-2.2-0.3-0.50.7-0.7-0.60.5-0.50.6-0.6
Intermittent access total locomotion2.32.614.8-1.33.5-3.8-0.1-0.50.6-0.6-0.60.5-0.50.5-0.5
Intermittent access standard deviation1.51.62.21.30.2-0.1-1.3-1.51.4-1.4-1.41.4-1.41.5-1.5
Left kidney weight0.00.00.1-0.4-0.10.10.2-0.0-0.10.10.10.1-0.10.3-0.3
Right kidney weight0.00.10.30.30.5-0.50.5-0.1-0.20.20.10.0-0.00.1-0.1
Cocaine induced anxiety0.10.20.70.80.00.00.50.3-0.30.30.3-0.30.3-0.30.3
Post-drug Anxiety0.40.52.41.5-0.10.10.80.6-0.60.60.6-0.60.6-0.60.6
Baseline Anxiety1.11.21.40.3-1.21.11.11.2-1.21.21.2-1.21.2-1.21.2
Tail length1.34.08.50.3-2.92.81.72.0-2.12.12.1-1.81.8-1.71.7
Length with tail2.07.59.90.5-2.32.03.03.1-3.13.13.1-2.92.9-2.82.8
Length without tail1.43.04.40.4-0.70.52.12.1-2.02.02.0-2.02.0-1.81.8
Times rat made contact with spout0.40.40.6-0.2-0.70.60.40.7-0.70.70.7-0.80.8-0.70.7
Lifetime Intake1.71.95.8-1.42.3-2.4-0.9-1.11.0-1.0-1.11.0-1.01.1-1.1
Liver weight, left0.20.30.6-0.3-0.40.5-0.8-0.50.5-0.5-0.50.4-0.40.5-0.5
Liver weight, right0.10.21.0-1.00.6-0.6-0.00.3-0.40.40.3-0.30.3-0.30.3
Locomotor activity0.40.63.3-1.8-1.11.1-0.9-0.20.3-0.3-0.20.2-0.20.2-0.2
Locomotor testing distance0.40.76.9-2.6-0.70.7-1.0-0.10.2-0.2-0.10.2-0.20.1-0.1
Locomotor testing rearing0.30.52.2-1.5-0.00.1-1.2-0.60.6-0.6-0.50.6-0.60.6-0.6
Locomotion in novel chamber3.03.75.20.62.3-2.3-1.7-1.92.2-2.2-1.91.9-1.91.8-1.8
Locomotion in novel chamber post-restriction2.32.83.8-0.50.9-0.8-1.8-1.92.0-2.0-1.91.8-1.81.9-1.9
Fecal boli incidents, locomotor time 11.11.23.11.81.0-0.9-0.6-1.11.0-1.0-1.01.0-1.01.0-1.0
Change in fecal boli incidents, locomotor task0.90.86.7-2.61.1-1.1-0.6-0.10.1-0.1-0.10.1-0.10.1-0.1
Time >=10cm from walls, locomotor time 14.04.17.30.52.7-2.7-1.6-1.92.0-2.0-2.11.9-1.91.9-1.9
Bouts of movement, locomotor time 11.11.25.52.4-2.12.20.30.10.1-0.1-0.2-0.10.1-0.10.1
Total resting periods, locomotor time 10.80.95.42.3-1.61.70.30.10.1-0.1-0.1-0.00.0-0.00.0
Rest time, locomotor task time 11.11.21.80.30.4-0.2-1.3-1.41.1-1.1-1.01.3-1.31.3-1.3
Distance moved, locomotor task time 10.30.30.4-0.40.4-0.40.60.6-0.50.50.5-0.70.7-0.60.6
Vertical activity count, locomotor time 10.50.50.7-0.60.7-0.7-0.8-0.70.8-0.8-0.80.6-0.60.7-0.7
Time >=10cm from walls, locomotor time 20.70.73.51.90.3-0.3-0.5-0.70.8-0.8-0.80.7-0.70.7-0.7
Bouts of movement, locomotor time 21.31.41.90.8-1.41.41.21.1-1.21.21.2-1.11.1-1.11.1
Total resting periods, locomotor time 20.60.61.00.7-1.01.00.80.7-0.80.80.8-0.70.7-0.70.7
Rest time, locomotor task time 22.63.04.1-0.81.2-1.0-2.0-2.01.9-1.9-1.91.9-1.91.9-1.9
Distance moved, locomotor task time 20.70.92.31.2-1.51.50.70.7-0.70.70.7-0.70.7-0.70.7
Vertical activity count, locomotor time 20.50.63.30.0-1.71.8-0.10.3-0.20.20.2-0.30.3-0.30.3
Light reinforcement 10.10.10.40.6-0.10.3-0.5-0.20.2-0.2-0.20.3-0.30.4-0.4
Light reinforcement 21.11.52.81.71.4-1.2-0.6-1.21.1-1.1-1.11.2-1.21.3-1.3
Bone: marrow area1.83.97.6-1.42.8-2.6-1.7-1.91.8-1.8-1.91.9-1.91.9-1.9
Bone: maximum diameter0.20.31.70.71.3-1.30.3-0.1-0.10.1-0.10.2-0.20.3-0.3
Bone: maximum force1.42.44.30.20.9-1.22.11.7-1.71.71.7-1.71.7-1.61.6
Bone: maximum moment1.32.34.00.20.7-0.92.01.7-1.71.71.7-1.61.6-1.61.6
Mean time between licks in bursts2.43.35.3-1.8-2.32.31.01.9-1.71.71.7-1.81.8-1.81.8
Mean num. licks in bursts0.00.10.30.1-0.50.5-0.10.10.1-0.10.1-0.10.1-0.20.2
Cd content in liver1.41.62.30.21.2-1.0-1.2-1.51.5-1.5-1.51.2-1.21.2-1.2
Co content in liver0.60.72.2-0.3-0.30.5-1.5-0.91.0-1.0-0.90.7-0.70.8-0.8
Cu content in liver0.60.71.1-0.8-1.11.00.60.8-0.70.70.8-0.80.8-0.80.8
Fe content in liver0.10.10.20.10.4-0.4-0.0-0.30.4-0.4-0.30.2-0.20.3-0.3
K content in liver0.60.61.0-0.10.4-0.61.01.0-1.01.01.0-0.70.7-0.70.7
Mg content in liver0.60.62.3-0.71.3-1.50.60.6-0.60.60.6-0.50.5-0.40.4
Mn content in liver1.31.52.40.9-0.40.21.61.5-1.41.41.4-1.21.2-1.31.3
Na content in liver0.30.30.70.90.3-0.40.70.5-0.60.60.5-0.40.4-0.30.3
Rb content in liver0.91.12.4-1.60.8-0.7-1.4-0.90.9-0.9-0.91.0-1.01.1-1.1
Se content in liver0.10.11.01.0-0.10.00.4-0.10.1-0.1-0.10.2-0.20.2-0.2
Sr content in liver4.23.85.81.0-1.51.22.42.1-2.22.22.1-2.12.1-2.12.1
Zn content in liver2.42.65.00.9-0.3-0.12.21.8-1.71.71.8-1.91.9-1.81.8
Bone: minimum diameter1.12.05.6-0.72.4-2.3-1.0-1.21.1-1.1-1.21.3-1.31.3-1.3
Time in familiar zone, hab. session 10.10.10.30.00.0-0.00.20.4-0.30.30.3-0.50.5-0.50.5
Time in novel zone, hab. session 10.70.71.5-0.60.4-0.3-1.2-0.90.8-0.8-0.81.0-1.00.9-0.9
Total zone transitions, hab. session 10.20.30.4-0.20.5-0.60.70.5-0.50.50.6-0.60.6-0.50.5
Total locomotion distance, hab. session 10.81.25.9-0.62.4-2.4-0.2-0.60.6-0.6-0.60.4-0.40.5-0.5
Locomotion velocity, hab. session 10.30.52.9-0.31.6-1.70.4-0.00.0-0.0-0.0-0.10.1-0.00.0
Time in familiar zone, hab. session 20.20.21.00.4-0.91.0-0.70.2-0.00.00.1-0.10.1-0.10.1
Time in novel zone, hab. session 20.30.30.7-0.80.4-0.60.80.4-0.50.50.4-0.50.5-0.40.4
Total zone transitions, hab. session 21.62.12.9-0.80.2-0.41.41.7-1.71.71.6-1.61.6-1.71.7
Total locomotion distance, hab. session 20.50.72.7-1.01.5-1.60.40.5-0.50.50.5-0.50.5-0.50.5
Locomotion velocity, hab. session 20.50.73.8-1.01.9-2.00.20.2-0.20.20.1-0.20.2-0.10.1
Novel to familiar place preference ratio1.21.32.40.3-1.41.31.61.1-1.21.21.1-1.11.1-1.01.0
Novelty place preference0.80.81.80.3-1.31.31.20.8-0.90.90.8-0.70.7-0.60.6
Time in novel zone, NPP test0.90.91.90.1-1.41.31.20.9-1.01.00.9-0.80.8-0.70.7
Total zone transitions, NPP test1.11.52.2-0.6-0.1-0.21.41.3-1.41.41.4-1.41.4-1.51.5
Total locomotion distance, NPP test0.30.41.6-1.30.9-1.00.40.3-0.30.30.3-0.40.4-0.30.3
Locomotion velocity, NPP test0.20.21.0-1.00.9-1.00.30.1-0.10.10.1-0.20.2-0.10.1
Intraocular pressure0.20.21.21.1-0.20.3-0.4-0.40.4-0.4-0.40.6-0.60.4-0.4
Delta distance traveled before/after self-admin0.20.20.7-0.60.1-0.0-0.8-0.50.5-0.5-0.30.5-0.50.5-0.5
Delta ambulatory time before/after self-admin0.40.51.1-0.9-0.30.5-1.0-0.70.7-0.7-0.60.7-0.70.7-0.7
Parametrial fat weight2.24.210.4-0.83.2-3.1-1.7-1.91.9-1.9-1.71.8-1.81.9-1.9
Pavlov. Cond. lever latency0.70.91.5-0.2-0.60.7-1.2-1.11.0-1.0-1.01.0-1.01.1-1.1
Pavlov. Cond. magazine entry latency0.50.61.41.20.8-0.91.00.7-0.60.60.7-0.70.7-0.70.7
Pavlov. Cond. change in total contacts0.40.52.21.51.2-1.30.4-0.10.3-0.3-0.20.1-0.10.0-0.0
Pavlov. Cond. index score0.30.41.61.30.5-0.60.80.6-0.40.40.5-0.50.5-0.50.5
Pavlov. Cond. latency score0.30.40.60.80.7-0.70.70.6-0.50.50.6-0.60.6-0.60.6
Pavlov. Cond. lever contacts0.20.20.40.30.6-0.60.50.5-0.40.40.4-0.40.4-0.40.4
Pavlov. Cond. magazine entry number0.40.54.2-2.0-0.20.3-0.8-0.40.2-0.2-0.40.4-0.40.4-0.4
Pavlov. Cond. intertrial magazine entries0.20.31.81.4-0.60.60.1-0.30.2-0.2-0.30.3-0.30.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.40.51.91.40.5-0.60.90.6-0.40.40.5-0.60.6-0.60.6
Pavlov. Cond. response bias0.40.42.21.50.4-0.50.80.5-0.40.40.5-0.50.5-0.60.6
Pavlov. Cond. lever latency0.20.30.5-0.60.1-0.1-0.6-0.60.7-0.7-0.60.6-0.60.6-0.6
Pavlov. Cond. magazine entry latency3.13.65.11.9-1.00.82.22.0-2.12.12.0-2.02.0-2.12.1
Pavlov. Cond. change in total contacts0.81.16.42.50.2-0.31.20.8-0.90.90.8-0.80.8-0.80.8
Pavlov. Cond. index score1.52.04.22.0-0.50.41.71.4-1.51.51.3-1.41.4-1.41.4
Pavlov. Cond. latency score1.31.63.31.8-0.30.21.61.2-1.41.41.2-1.31.3-1.31.3
Pavlov. Cond. lever contacts0.30.41.91.4-0.60.60.50.5-0.60.60.5-0.50.5-0.50.5
Pavlov. Cond. magazine entry number4.85.88.7-2.31.3-1.0-3.0-2.52.6-2.6-2.52.5-2.52.6-2.6
Pavlov. Cond. intertrial magazine entries1.62.02.9-0.10.9-0.8-1.5-1.61.5-1.5-1.51.6-1.61.7-1.7
Pavlov. Cond. lever-magazine prob. diff.1.92.44.52.1-0.60.51.81.5-1.71.71.5-1.51.5-1.61.6
Pavlov. Cond. response bias1.11.62.81.7-0.80.81.41.2-1.31.31.2-1.31.3-1.21.2
Time in closed arm before self-admin0.30.31.41.20.6-0.5-0.2-0.50.4-0.4-0.40.5-0.50.5-0.5
Time in closed arm after self-admin0.30.32.1-1.5-0.20.3-0.7-0.50.2-0.2-0.40.5-0.50.5-0.5
Time in open arm before self-admin0.60.76.4-2.5-0.60.7-0.8-0.10.1-0.1-0.20.1-0.10.1-0.1
Time in open arm after self-admin0.20.31.30.5-1.11.10.20.20.0-0.00.2-0.30.3-0.20.2
Bone: periosteal estimation0.51.04.7-0.12.2-2.2-0.2-0.60.4-0.4-0.60.6-0.60.7-0.7
Bone: periosteal perimeter0.50.83.20.61.8-1.8-0.2-0.50.3-0.3-0.50.6-0.60.7-0.7
Bone: post-yield work1.72.39.00.13.0-3.0-0.5-1.21.1-1.1-1.21.0-1.01.0-1.0
Progressive ratio test 1 active lever presses2.12.23.0-0.41.2-1.2-1.4-1.61.7-1.7-1.71.6-1.61.6-1.6
Progressive ratio test 1 breakpoint2.42.53.3-0.31.3-1.2-1.5-1.71.8-1.8-1.81.7-1.71.7-1.7
Progressive ratio test 1 inactive lever presses0.20.21.9-1.40.3-0.50.30.3-0.30.30.2-0.30.3-0.30.3
Progressive ratio test 2 active lever presses2.42.64.3-0.22.1-2.1-1.3-1.61.6-1.6-1.61.6-1.61.6-1.6
Progressive ratio test 2 breakpoint3.13.54.20.01.9-1.8-1.7-2.02.1-2.1-2.02.0-2.02.0-2.0
Progressive ratio test 2 inactive lever presses1.51.75.2-0.42.2-2.3-0.8-1.11.1-1.1-1.11.1-1.11.1-1.1
Incentive Sensitization - Responses0.20.21.00.20.9-1.00.30.00.0-0.00.0-0.00.0-0.00.0
Incentive Sensitization - Breakpoint0.30.31.60.21.2-1.20.1-0.10.1-0.1-0.10.1-0.10.1-0.1
Sum of active levers in priming session hrs 5-61.21.212.23.5-0.60.60.80.2-0.30.30.3-0.30.3-0.20.2
Progressive ratio0.00.00.10.30.3-0.3-0.00.10.1-0.10.10.2-0.2-0.10.1
Food seeking constrained by brief footshock0.10.10.7-0.90.2-0.1-0.2-0.0-0.10.10.00.0-0.0-0.10.1
Seeking ratio, punishment vs. effort0.20.22.0-1.4-0.20.2-0.10.1-0.20.20.1-0.30.3-0.10.1
Retroperitoneal fat weight1.96.48.0-2.71.9-1.6-2.8-2.52.5-2.5-2.52.7-2.72.7-2.7
Reaction time number correct1.01.42.00.0-1.21.10.81.3-1.41.41.4-1.21.2-1.21.2
Reaction time mean minus median0.60.87.72.8-0.80.80.4-0.20.4-0.4-0.30.2-0.20.2-0.2
Reaction time mean minus median AUC0.60.85.62.4-1.41.40.2-0.10.3-0.3-0.30.2-0.20.1-0.1
Reaction time num false alarms0.30.42.5-1.6-1.11.2-0.30.1-0.10.10.1-0.20.2-0.20.2
Reaction time num false alarms AUC0.81.13.6-1.5-1.91.90.20.6-0.70.70.7-0.80.8-0.70.7
Reaction time trials correct on left1.01.42.00.0-1.21.10.81.3-1.41.41.4-1.21.2-1.21.2
Reaction time trials on left1.01.52.00.1-1.31.20.81.3-1.41.41.4-1.21.2-1.21.2
Reaction time mean0.60.84.72.20.1-0.0-0.3-0.81.0-1.0-0.80.6-0.60.6-0.6
Reaction time mean AUC0.70.95.02.20.2-0.1-0.5-0.91.0-1.0-0.90.7-0.70.7-0.7
Median of all reaction times0.20.32.21.50.4-0.4-0.0-0.50.6-0.6-0.50.3-0.30.2-0.2
Reaction time omissions0.40.52.41.2-1.51.50.2-0.10.1-0.1-0.1-0.20.2-0.20.2
Reaction time false alarm rate0.20.32.3-1.5-0.60.7-0.3-0.20.2-0.2-0.20.1-0.10.1-0.1
Reaction time premature initiation rate4.66.28.9-1.1-1.31.12.43.0-3.03.03.0-2.72.7-2.62.6
Reaction time premature initiations6.49.112.6-0.7-2.42.12.83.5-3.53.53.5-3.33.3-3.13.1
Std. dev. reaction times0.91.26.52.6-0.70.9-0.4-0.91.1-1.1-1.00.8-0.80.8-0.8
Reaction time trials completed1.01.52.00.1-1.31.20.81.3-1.41.41.4-1.21.2-1.21.2
Reaction time trials AUC0.81.21.7-0.1-1.00.90.71.3-1.31.31.3-1.21.2-1.11.1
Run reversals in cocaine runway, females1.91.96.8-2.60.3-0.61.01.4-1.31.31.4-1.31.3-1.41.4
Run reversals in cocaine runway, males0.40.40.6-0.10.3-0.3-0.8-0.70.6-0.6-0.70.6-0.60.7-0.7
Latency to leave start box in cocaine runway0.50.61.9-1.01.4-1.3-0.5-0.40.6-0.6-0.50.6-0.60.4-0.4
Latency to leave start box in cocaine runway, F0.00.00.1-0.20.4-0.40.10.1-0.00.00.10.0-0.0-0.10.1
Latency to leave start box in cocaine runway, M2.32.33.4-0.91.2-1.0-1.8-1.51.7-1.7-1.51.6-1.61.5-1.5
Std. dev. time between licks in bursts0.40.52.0-1.4-0.91.0-0.30.5-0.40.40.3-0.50.5-0.50.5
Total sessions with >9 infusions1.92.14.7-2.21.8-1.8-1.2-1.31.3-1.3-1.21.1-1.11.2-1.2
Short access day 1 total inactive lever presses1.31.43.9-1.81.8-2.0-0.9-0.80.9-0.9-0.90.8-0.80.8-0.8
Short access day 10 total inactive lever presses1.61.83.0-1.71.1-1.1-1.6-1.31.3-1.3-1.41.3-1.31.3-1.3
Short access day 1 total infusions1.21.33.5-1.91.6-1.6-0.9-0.90.8-0.8-0.90.8-0.80.9-0.9
Short access day 10 total infusions1.71.98.7-2.22.7-2.9-0.3-0.40.4-0.4-0.50.4-0.40.4-0.4
Short access total infusions1.21.35.5-2.41.9-2.0-0.5-0.50.5-0.5-0.60.5-0.50.5-0.5
Short access day 1 locomotion1.01.04.7-2.21.7-2.00.30.2-0.30.30.2-0.30.3-0.20.2
Short access day 10 total locomotion0.91.05.2-1.52.1-2.30.20.1-0.10.10.1-0.10.1-0.10.1
Short access total locomotion1.21.35.0-2.12.0-2.20.50.4-0.40.40.4-0.50.5-0.40.4
One hour access (0.3 mA shock)4.55.38.0-0.72.8-2.8-2.2-2.32.3-2.3-2.22.3-2.32.3-2.3
Compulsive drug intake3.13.18.0-0.7-2.82.81.11.5-1.61.61.6-1.51.5-1.51.5
One hour access (shock baseline)7.18.212.00.73.5-3.3-2.5-3.02.9-2.9-2.82.9-2.93.0-3.0
Social response proportion0.30.30.7-0.3-0.80.80.40.6-0.70.70.6-0.40.4-0.40.4
Social responses0.30.41.50.4-1.21.20.20.5-0.50.50.5-0.40.4-0.30.3
Social time0.30.32.0-0.2-1.31.4-0.00.2-0.40.40.3-0.00.0-0.10.1
Soleus weight1.95.78.5-1.01.8-1.5-2.9-2.62.5-2.5-2.62.6-2.62.6-2.6
Bone: stiffness0.30.51.21.10.7-0.81.00.7-0.70.70.7-0.60.6-0.60.6
Tibialis anterior weight7.124.237.31.4-3.02.36.15.5-5.55.55.5-5.45.4-5.45.4
Time to tail flick, vehicle, before self-admin0.50.52.0-0.61.2-1.40.70.4-0.50.50.5-0.50.5-0.40.4
Time to tail flick, vehicle, after self-admin0.70.82.0-1.4-0.10.00.70.9-1.01.00.9-0.90.9-0.90.9
Time to tail flick, test, before self-admin1.11.05.9-2.40.2-0.50.60.8-0.90.90.8-0.80.8-0.80.8
Time to tail flick, test, after self-admin0.10.10.20.1-0.30.4-0.3-0.40.1-0.1-0.30.3-0.30.4-0.4
Delta time to tail flick, vehicle, before/after SA0.20.20.3-0.6-0.60.50.10.4-0.30.30.3-0.30.3-0.40.4
Delta time to tail flick, test, before/after SA0.90.85.22.3-0.91.1-0.3-0.50.5-0.5-0.50.5-0.50.5-0.5
Tibia length0.61.65.42.30.6-0.91.91.2-1.01.01.1-0.90.9-0.90.9
Ambulatory time before self-admin1.21.25.82.40.2-0.31.30.9-1.01.01.0-0.90.9-0.90.9
Ambulatory time after self-admin0.20.21.91.40.2-0.20.30.1-0.10.10.3-0.20.2-0.10.1
Bone: tissue strength0.10.10.30.2-0.20.4-0.6-0.10.2-0.2-0.10.4-0.40.3-0.3
Total heroin consumption3.54.05.81.8-2.42.32.11.9-1.91.92.0-1.91.9-1.91.9
Bone: trabecular number0.60.92.4-0.11.3-1.51.00.8-0.70.70.8-0.90.9-0.90.9
Bone: trabecular spacing0.30.42.4-0.1-1.31.6-0.6-0.10.0-0.0-0.10.2-0.20.3-0.3
Bone: trabecular thickness0.81.02.00.91.4-1.4-0.6-1.01.0-1.0-1.00.8-0.80.7-0.7
Bone: trabecular tissue density3.34.66.4-0.31.0-0.6-2.5-2.52.4-2.4-2.52.4-2.42.4-2.4
Water consumed over 24 hours0.70.81.10.4-0.90.90.70.9-1.01.01.0-0.90.9-0.90.9
Number of responses in last shaping day0.20.21.4-1.2-0.60.70.10.1-0.20.20.1-0.20.2-0.10.1