Hub : Genes

Sf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression Sf1 0.17 0.1 5.0e-03 0 -0 -0.01 0 3.1e-01 3.8e-01 9.6e-01 2.3e-01
2 Brain alternative TSS XM_063269208.1 0.03 0.02 4.0e-04 0.03 0.04 0.03 0.03 6.4e-04 2.3e-04 9.1e-04 4.0e-04
3 NAcc alternative TSS XM_063268967.1 0.02 0.01 1.2e-03 0.01 0.01 0.01 0.01 4.0e-02 1.3e-02 2.1e-02 2.5e-02
4 LHb gene expression Sf1 0.2 0.12 1.3e-03 0.13 0.09 0.03 0.07 5.5e-04 3.5e-03 6.1e-02 7.6e-03
5 Brain alternative TSS XM_063268967.1 0.02 0.02 9.0e-03 0.02 0.02 0.01 0.01 7.5e-03 8.2e-03 7.0e-02 1.3e-02
6 Brain alternative TSS XM_063269208.1 0.03 0.02 4.1e-04 0.04 0.04 0.03 0.04 8.7e-05 2.3e-04 8.6e-04 3.2e-04
7 Adipose alternative TSS XM_063268843.1 0.07 0.04 5.0e-05 0 0.03 0.02 0.01 1.0e-01 8.6e-04 3.6e-03 1.9e-02
8 Brain isoform ratio XM_063268967.1 0.04 0.03 2.4e-03 0 0.01 0.01 0 3.4e-01 8.6e-02 3.7e-02 1.3e-01
9 NAcc gene expression Sf1 0.02 0.02 9.9e-03 0.01 0.01 0.01 0.01 3.6e-02 1.7e-02 4.4e-03 3.6e-02
10 PL gene expression Sf1 0.02 0.02 1.0e-02 0.01 0.01 0.02 0.01 2.0e-02 8.0e-03 5.5e-03 1.5e-02
11 PL alternative TSS XM_063268967.1 0.4 0.28 8.0e-03 0.02 0.01 0.04 0.03 6.6e-03 2.4e-02 5.2e-05 5.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.20.41.4-0.3-0.30.1-0.60.7-0.7-0.5-0.31.0-1.2-0.5
Area under the delay curve0.20.20.7-0.0-0.20.1-0.20.4-0.40.60.50.80.0-0.6
BMI with tail0.93.310.7-1.2-1.20.7-2.22.4-2.4-1.00.22.1-3.3-0.4
BMI without tail0.72.13.8-0.9-1.31.1-1.81.9-1.90.11.21.1-2.0-1.3
Body weight1.98.217.4-2.8-2.92.6-3.63.7-3.7-1.81.8-0.9-4.21.5
Weight adjusted by age1.31.93.1-1.7-1.31.3-1.41.4-1.4-1.50.6-1.5-1.01.8
Bone surface2.03.68.9-2.4-1.71.5-2.22.1-2.1-3.00.1-0.5-2.30.8
Bone volume0.61.04.6-1.2-0.50.3-0.90.9-0.9-2.1-0.80.4-1.30.2
Breakpoint value in progressive ratio session2.02.44.8-2.2-1.71.6-1.61.9-1.9-2.00.9-0.8-0.80.6
Number of licking bursts0.10.20.6-0.6-0.40.4-0.40.4-0.4-0.80.0-0.1-0.20.0
Context. condit. distance diff. score1.01.22.71.41.2-1.11.3-1.01.01.6-0.21.10.8-0.4
Locomotion velocity, session 10.40.41.00.2-0.50.5-0.50.4-0.40.81.0-1.0-0.80.6
Locomotion distance, session 10.40.52.20.1-0.60.5-1.10.7-0.70.40.50.3-1.5-0.6
Locomotion velocity, session 21.61.83.4-1.3-1.51.4-1.91.7-1.7-0.90.9-0.1-1.8-0.1
Locomotion distance, session 20.50.72.1-0.3-0.90.8-1.31.0-1.00.30.70.2-1.4-0.7
Locomotion velocity, session 30.60.71.71.30.7-0.80.1-0.50.51.2-0.50.9-1.2-0.7
Locomotion distance, session 30.00.00.20.30.1-0.10.0-0.00.00.40.1-0.1-0.30.4
Stereotopy head waving bouts, day 30.91.03.01.60.9-1.00.4-0.70.71.7-0.61.0-1.3-0.2
Stereotopy head waving duration, day 30.70.91.81.31.0-1.10.8-1.01.01.0-0.91.0-0.3-0.6
Locomotion velocity, session 71.01.13.51.21.0-1.10.5-0.80.80.9-1.11.9-0.3-1.2
Locomotion distance, session 70.20.31.50.6-0.0-0.1-0.30.1-0.11.20.10.7-1.0-0.2
Stereotopy head waving bouts, day 70.30.30.80.00.6-0.70.6-0.50.5-0.7-0.90.80.40.2
Stereotopy head waving duration, day 70.30.42.0-1.0-0.30.2-0.30.5-0.5-1.4-0.20.5-0.0-0.0
Locomotion velocity, session 81.82.25.0-0.8-1.41.4-1.41.4-1.40.21.7-1.5-1.62.2
Locomotion distance, session 80.30.41.01.00.7-0.80.4-0.40.41.0-0.31.0-0.6-0.1
Degree of sensitization distance0.20.31.10.50.2-0.3-0.20.0-0.00.7-0.20.8-1.0-0.3
Degree of sensitization stereotypy0.30.32.2-0.8-0.0-0.0-0.00.1-0.1-1.5-0.50.30.30.0
Conditioned locomotion1.31.52.5-1.2-1.31.3-1.61.3-1.3-0.71.1-1.0-1.50.6
Cocaine response after cond. corrected0.70.83.91.30.8-0.80.7-0.70.72.0-0.10.4-0.30.3
Cocaine response after cond. not corrected0.50.62.81.10.7-0.70.6-0.50.51.7-0.20.3-0.40.5
Cocaine response before conditioning0.40.52.1-1.0-0.60.5-0.40.6-0.6-1.5-0.3-0.40.10.3
Saline control response4.25.57.5-2.3-2.62.5-2.72.7-2.7-1.22.0-1.7-2.32.6
Bone: connectivity density1.11.83.4-1.5-1.31.1-1.61.7-1.7-1.40.30.2-1.90.3
Bone: cortical apparent density0.20.30.9-0.7-0.50.6-0.30.3-0.3-0.40.7-0.50.9-0.3
Bone: cortical area0.40.61.5-0.9-0.60.6-0.70.7-0.7-1.20.0-0.4-0.81.0
Bone: cortical porosity0.30.32.0-0.3-0.30.2-0.40.3-0.3-0.30.30.6-0.1-1.4
Bone: cortical porosity0.50.51.1-0.7-0.70.7-0.80.8-0.8-0.50.70.4-0.6-1.0
Bone: cortical thickness3.05.07.2-2.5-2.62.7-2.42.4-2.4-1.32.4-2.3-1.21.9
Bone: cortical thickness1.31.63.3-0.8-1.41.5-1.21.3-1.30.61.8-1.6-0.80.6
Bone: cortical tissue density0.30.40.9-0.9-0.70.8-0.50.5-0.5-0.50.9-0.70.8-0.3
Condit. Reinf. active minus inactive responses0.20.20.4-0.4-0.40.4-0.50.6-0.6-0.10.50.40.0-0.7
Condit. Reinf. active-inactive response ratio0.10.20.6-0.5-0.30.4-0.20.3-0.3-0.20.50.10.8-0.4
Condit. Reinf. active responses0.20.21.20.10.2-0.20.00.0-0.0-0.0-0.21.0-0.0-1.1
Condit. Reinf. inactive responses0.60.71.90.80.9-1.00.5-0.60.60.2-1.11.4-0.5-1.0
Incentive salience index mean0.30.41.6-0.3-0.40.3-0.60.7-0.7-0.10.40.8-0.5-1.3
Condit. Reinf. lever presses0.20.30.8-0.4-0.20.1-0.40.5-0.5-0.7-0.20.7-0.9-0.7
Condit. Reinf. active minus inactive responses0.30.40.90.30.7-0.80.7-0.80.8-0.6-0.90.50.6-0.2
Condit. Reinf. active-inactive response ratio1.71.94.21.21.7-1.81.5-1.61.6-0.4-2.01.30.5-0.4
Condit. Reinf. active responses0.10.10.6-0.40.0-0.10.0-0.10.1-0.8-0.20.30.5-0.4
Condit. Reinf. inactive responses0.60.82.0-1.0-1.11.1-1.01.1-1.1-0.21.4-0.2-0.0-0.4
Condit. Reinf. lever presses0.81.14.5-1.5-0.80.7-1.00.8-0.8-2.1-0.1-0.7-0.70.6
Condit. Reinf. lever reinforcers received0.10.21.3-0.7-0.30.2-0.20.2-0.2-1.1-0.0-0.10.4-0.1
Conditioned reinforcement - actives0.61.03.20.00.8-0.80.6-0.80.8-1.8-1.8-0.70.31.3
Conditioned reinforcement - inactives2.94.26.81.82.5-2.42.6-2.42.4-0.3-2.60.72.20.4
Conditioned locomotion6.78.714.43.13.5-3.43.5-3.83.81.1-3.11.13.0-0.1
Patch foraging indifference point 0 sec0.00.10.20.30.2-0.20.3-0.20.20.1-0.20.50.3-0.0
Patch foraging indifference point AUC1.52.25.6-2.1-1.41.4-1.31.4-1.4-2.40.7-1.5-0.11.1
Delay disc. indifference point, 0s delay0.20.31.40.60.1-0.20.10.3-0.31.20.20.9-0.1-0.4
Delay disc. indifference point, 16s delay1.01.12.40.81.0-1.00.9-1.11.10.3-0.81.41.1-1.5
Delay disc. indifference point, 2s delay0.20.20.50.30.4-0.50.40.0-0.00.3-0.50.6-0.10.7
Delay disc. indifference point, 24s delay0.10.20.7-0.1-0.40.4-0.20.2-0.20.70.8-0.10.10.3
Delay disc. indifference point, 4s delay0.40.41.40.1-0.30.3-0.30.7-0.71.20.90.7-0.20.2
Delay disc. indifference point, 8s delay0.30.30.8-0.0-0.40.4-0.40.5-0.50.90.90.4-0.3-0.7
Indifference point function ln k3.86.616.43.72.6-2.62.6-2.72.74.1-1.22.21.0-1.0
Indifference point function log k3.86.616.43.72.6-2.62.6-2.72.74.1-1.22.21.0-1.0
Patch foraging total patch changes 0 sec0.00.00.10.1-0.10.20.00.1-0.10.30.30.00.10.4
Patch foraging total patch changes 12 sec2.93.76.0-2.5-2.22.2-2.32.2-2.2-2.01.5-1.3-1.10.9
Patch foraging total patch changes 18 sec0.30.51.4-0.9-0.60.6-0.60.9-0.9-1.20.20.1-0.10.4
Patch foraging total patch changes 24 sec1.62.75.4-1.8-1.71.7-1.51.7-1.7-1.51.3-1.8-0.72.3
Patch foraging total patch changes 6 sec0.81.11.8-1.0-1.31.2-1.31.3-1.3-0.41.1-0.5-1.00.9
Patch foraging time to switch 0 sec0.51.02.2-1.1-0.60.4-1.11.0-1.0-1.5-0.30.9-1.3-1.3
Patch foraging water rate 0 sec1.42.94.72.11.8-1.62.2-2.02.01.9-0.60.11.90.6
Patch foraging water rate 12 sec2.65.513.43.32.3-2.12.8-2.72.73.7-0.30.51.80.7
Patch foraging water rate 18 sec1.21.96.92.11.3-1.21.3-1.51.52.6-0.10.50.20.3
Patch foraging water rate 24 sec1.62.35.52.11.6-1.51.8-1.61.62.3-0.50.50.81.0
Patch foraging water rate 6 sec1.72.49.82.41.4-1.21.5-1.61.63.10.20.30.70.0
Seeking ratio, delayed vs. immediate footshock0.40.53.20.50.4-0.40.2-0.30.30.5-0.21.20.4-1.8
Distance traveled before self-admin0.30.42.3-0.9-0.20.2-0.40.5-0.5-1.5-0.50.3-0.1-0.3
Distance traveled after self-admin0.20.30.9-0.8-0.40.4-0.30.3-0.3-1.00.30.00.7-0.6
Extensor digitorum longus weight5.320.730.4-5.2-5.14.9-5.55.5-5.5-3.63.7-2.8-4.61.9
Bone: elastic displacement0.40.52.60.80.10.10.4-0.40.41.60.9-0.70.20.6
Bone: elastic work1.72.24.8-1.0-1.71.7-1.61.6-1.60.52.2-1.4-1.40.7
Bone: endosteal estimation1.43.05.82.01.9-2.11.4-1.51.50.9-2.12.4-0.8-1.5
Bone: endosteal perimeter2.04.28.52.22.5-2.72.0-2.02.00.3-2.92.5-0.3-1.1
Epididymis fat weight2.89.715.33.53.9-3.93.8-3.73.71.3-3.52.41.7-0.5
Delta time in closed arm before/after self-admin1.21.12.2-0.1-1.11.1-1.10.9-0.91.41.5-0.7-1.40.1
Delta time in open arm before/after self-admin0.50.53.5-0.90.1-0.10.30.2-0.2-1.9-0.5-0.20.90.3
Diff in mean of infusions in LGA sessions0.70.81.4-1.0-1.01.0-0.80.9-0.9-0.50.8-0.9-0.71.2
Delay discount exponential model param0.10.20.40.20.3-0.30.2-0.50.5-0.5-0.6-0.6-0.00.3
Extinction: sum of active levers before priming1.31.42.6-1.5-1.31.2-1.41.6-1.6-1.30.5-0.3-0.90.4
Active lever presses in extinction session 62.32.35.5-1.9-1.31.2-1.41.5-1.5-2.40.2-1.2-1.21.7
Bone: final force1.32.13.5-1.7-1.51.4-1.81.6-1.6-1.60.6-0.8-1.90.5
Bone: final moment1.22.03.4-1.6-1.51.4-1.71.6-1.6-1.50.6-0.8-1.80.5
Food consumed during 24 hour testing period0.30.52.2-0.5-0.00.10.1-0.20.2-1.0-0.4-0.90.61.5
Glucose2.43.86.72.62.1-2.21.7-1.71.72.0-1.72.50.1-1.7
Heart weight1.31.95.81.80.9-1.10.5-0.30.32.4-0.42.4-1.3-1.5
Delay discount hyperbolic model param0.10.10.50.10.2-0.20.2-0.50.5-0.5-0.4-0.7-0.00.1
Intermittent access intake day 1-15 change1.02.03.21.01.6-1.61.8-1.71.7-0.4-1.80.21.61.0
Intermittent access intake escalation0.91.93.20.81.6-1.51.7-1.61.6-0.6-1.8-0.01.61.1
Intermittent access intake escalation 21.41.62.70.81.5-1.41.6-1.51.5-0.6-1.6-0.01.50.9
Intermitt. access day 1 inactive lever presses0.10.31.30.30.4-0.40.6-0.70.7-0.1-0.2-0.41.1-0.2
Intermitt. access day 15 inactive lever presses1.63.45.11.82.3-2.22.0-2.32.3-0.0-2.21.01.5-1.0
Intermitt. access escalation Index2.02.95.71.91.6-1.61.8-1.61.61.8-1.02.41.4-1.6
Intermittent access day 1 total infusions3.25.28.82.72.8-2.92.1-2.32.30.9-3.02.70.5-1.4
Intermittent access day 15 total infusions5.68.314.93.03.7-3.73.3-3.43.40.4-3.91.71.90.1
Intermittent access terminal intake (last 3 days)5.77.515.52.83.6-3.63.1-3.03.00.2-3.91.91.50.2
Intermittent access total infusions5.26.211.92.83.2-3.32.6-2.72.70.5-3.52.20.9-0.6
Intermittent access day 1 locomotion2.63.35.42.22.2-2.31.8-1.91.90.8-2.31.90.7-0.7
Intermittent access day 15 total locomotion4.17.414.22.53.4-3.53.1-3.13.1-0.2-3.81.82.1-0.1
Intermittent access total locomotion9.110.920.43.44.1-4.23.6-3.63.60.2-4.52.92.1-1.0
Intermittent access standard deviation0.81.62.81.31.6-1.51.7-1.61.60.3-1.3-0.31.20.6
Left kidney weight0.52.54.01.71.9-2.01.9-1.51.50.8-1.81.81.0-0.3
Right kidney weight0.31.11.91.21.4-1.41.3-1.21.20.4-1.30.50.60.5
Cocaine induced anxiety0.10.10.7-0.10.1-0.10.1-0.10.1-0.8-0.5-0.30.30.4
Post-drug Anxiety0.40.40.9-0.7-0.60.5-0.70.5-0.5-1.00.0-0.7-0.80.6
Baseline Anxiety0.60.71.4-0.6-1.01.0-0.90.7-0.70.51.2-0.9-1.00.6
Tail length0.83.15.3-1.7-2.02.1-1.81.8-1.8-0.32.3-2.3-0.81.2
Length with tail2.08.811.2-3.0-3.33.3-3.33.2-3.2-1.33.0-3.2-2.82.4
Length without tail2.27.18.9-2.5-3.02.9-3.02.8-2.8-0.92.7-2.8-2.92.4
Times rat made contact with spout0.60.71.7-0.8-1.11.1-1.01.0-1.0-0.11.3-0.2-0.2-0.6
Lifetime Intake3.54.37.72.52.6-2.72.1-2.22.20.8-2.81.90.6-0.7
Liver weight, left0.40.72.41.30.8-0.90.8-0.70.71.5-0.10.3-0.30.3
Liver weight, right1.12.07.92.31.2-1.21.3-1.21.22.8-0.10.4-0.31.0
Locomotor activity0.81.25.71.60.9-0.81.1-1.01.02.40.3-0.20.40.5
Locomotor testing distance0.91.68.41.80.9-0.71.0-1.01.02.90.7-0.40.30.7
Locomotor testing rearing0.71.46.91.80.9-0.81.1-1.11.12.60.6-0.10.50.2
Locomotion in novel chamber4.75.98.92.83.0-2.92.8-3.03.01.3-2.71.71.6-0.5
Locomotion in novel chamber post-restriction2.74.45.82.12.4-2.42.4-2.42.40.8-2.21.62.0-1.8
Fecal boli incidents, locomotor time 10.30.52.1-0.30.5-0.50.7-0.20.2-1.4-1.10.10.70.5
Change in fecal boli incidents, locomotor task0.50.52.00.6-0.20.2-0.70.2-0.21.40.70.4-1.2-0.6
Time >=10cm from walls, locomotor time 12.22.35.91.21.8-2.01.5-1.31.3-0.5-2.42.10.5-0.8
Bouts of movement, locomotor time 11.51.73.7-1.9-1.31.4-1.51.0-1.0-1.91.0-1.00.9-1.0
Total resting periods, locomotor time 11.01.13.5-1.5-0.91.0-1.00.7-0.7-1.90.4-0.51.0-1.0
Rest time, locomotor task time 11.11.42.21.31.4-1.41.3-1.51.50.4-1.00.81.2-0.6
Distance moved, locomotor task time 10.10.20.6-0.3-0.30.2-0.20.6-0.60.20.10.5-0.70.2
Vertical activity count, locomotor time 10.30.71.31.10.9-0.90.9-0.90.91.1-0.50.30.30.2
Time >=10cm from walls, locomotor time 20.30.42.0-0.40.3-0.30.3-0.30.3-1.4-0.70.30.8-0.3
Bouts of movement, locomotor time 20.30.61.4-1.0-0.70.8-0.80.5-0.5-0.80.7-0.10.5-1.2
Total resting periods, locomotor time 20.20.42.1-0.6-0.40.4-0.50.2-0.2-0.60.40.20.6-1.4
Rest time, locomotor task time 22.32.94.52.01.8-1.81.5-1.91.91.3-1.21.61.1-2.1
Distance moved, locomotor task time 21.41.62.6-1.6-1.41.4-1.21.3-1.3-1.01.0-1.3-0.61.6
Vertical activity count, locomotor time 20.60.83.7-0.3-0.60.7-0.40.4-0.40.60.9-1.6-0.41.9
Light reinforcement 10.10.10.90.20.10.00.4-0.40.40.10.3-0.20.90.0
Light reinforcement 21.52.44.81.31.7-1.71.7-2.12.1-0.7-2.20.51.00.1
Bone: marrow area1.53.26.52.22.0-2.21.5-1.51.51.1-2.12.5-0.8-1.7
Bone: maximum diameter0.30.62.0-0.20.3-0.40.1-0.20.2-1.4-1.1-0.1-0.81.4
Bone: maximum force1.32.35.3-1.7-1.31.1-1.91.7-1.7-2.2-0.0-0.2-2.30.2
Bone: maximum moment1.22.15.0-1.7-1.31.1-1.81.7-1.7-2.00.1-0.1-2.20.2
Mean time between licks in bursts0.51.32.6-0.4-1.31.3-1.41.2-1.21.01.6-0.8-1.30.6
Mean num. licks in bursts0.10.10.70.30.00.00.1-0.10.10.80.50.10.4-0.5
Cd content in liver1.71.93.30.71.6-1.51.8-1.51.5-0.4-1.61.01.8-0.9
Co content in liver0.60.72.40.50.10.10.6-0.40.41.51.3-0.51.50.2
Cu content in liver0.20.31.00.00.2-0.10.2-0.10.1-0.1-0.01.00.9-1.0
Fe content in liver0.70.85.4-0.4-0.40.4-0.50.4-0.4-0.10.3-1.2-1.22.3
K content in liver0.70.71.6-0.4-0.70.6-0.81.1-1.10.30.80.5-1.30.6
Mg content in liver0.30.31.50.70.2-0.30.3-0.00.01.20.41.1-0.1-0.3
Mn content in liver1.92.14.4-1.8-1.41.3-1.61.4-1.4-2.10.4-1.1-1.41.5
Na content in liver0.60.71.7-0.7-0.80.8-0.60.7-0.7-0.50.9-1.1-0.51.3
Rb content in liver1.21.44.01.51.1-1.11.1-1.11.12.0-0.11.10.6-1.0
Se content in liver0.50.61.60.20.8-0.90.8-0.80.8-0.7-1.30.40.60.8
Sr content in liver2.42.13.1-1.8-1.51.6-1.41.5-1.5-1.70.9-1.6-0.61.2
Zn content in liver0.30.40.8-0.7-0.80.8-0.60.9-0.9-0.30.60.20.1-0.2
Bone: minimum diameter1.63.07.61.81.8-2.01.4-1.41.40.7-1.92.8-0.0-2.2
Time in familiar zone, hab. session 10.30.31.10.60.6-0.70.6-0.40.40.5-0.51.10.10.4
Time in novel zone, hab. session 10.20.20.90.4-0.20.3-0.20.0-0.01.00.7-0.9-0.3-0.2
Total zone transitions, hab. session 10.30.40.7-0.7-0.70.7-0.80.6-0.6-0.70.7-0.2-0.1-0.3
Total locomotion distance, hab. session 10.40.61.11.10.9-0.90.6-0.80.80.6-0.51.1-0.1-0.4
Locomotion velocity, hab. session 10.10.10.60.50.4-0.40.1-0.30.30.2-0.10.8-0.1-0.3
Time in familiar zone, hab. session 21.01.04.3-0.2-0.70.8-0.50.8-0.81.11.2-0.6-0.92.1
Time in novel zone, hab. session 20.50.53.7-0.00.2-0.30.0-0.30.3-0.7-0.60.50.5-1.9
Total zone transitions, hab. session 20.91.12.9-0.5-0.90.7-1.41.1-1.1-0.30.60.8-1.5-1.7
Total locomotion distance, hab. session 20.50.72.80.80.2-0.4-0.30.0-0.00.80.01.5-1.0-1.7
Locomotion velocity, hab. session 20.60.93.11.10.6-0.70.1-0.30.30.7-0.41.8-0.8-1.7
Novel to familiar place preference ratio0.70.74.4-1.4-0.30.3-0.40.4-0.4-2.1-0.9-0.30.30.1
Novelty place preference0.50.53.0-1.0-0.00.0-0.00.1-0.1-1.7-1.0-0.10.6-0.1
Time in novel zone, NPP test0.30.42.1-0.9-0.10.0-0.10.2-0.2-1.4-0.9-0.20.50.0
Total zone transitions, NPP test1.21.73.0-1.5-1.41.3-1.71.6-1.6-1.20.9-0.3-1.4-0.6
Total locomotion distance, NPP test0.30.42.50.40.0-0.1-0.40.1-0.10.40.10.7-0.7-1.6
Locomotion velocity, NPP test0.30.43.30.2-0.0-0.1-0.30.1-0.10.10.10.7-0.4-1.8
Intraocular pressure1.11.63.90.51.4-1.21.7-1.41.4-0.8-1.4-0.12.00.3
Delta distance traveled before/after self-admin0.30.31.30.2-0.30.4-0.1-0.00.01.11.2-0.50.30.1
Delta ambulatory time before/after self-admin0.30.41.80.1-0.50.6-0.30.2-0.21.01.4-0.80.1-0.1
Parametrial fat weight3.37.811.23.23.3-3.33.2-3.13.11.5-3.02.81.6-1.5
Pavlov. Cond. lever latency0.20.20.40.40.4-0.30.5-0.60.60.3-0.2-0.40.60.7
Pavlov. Cond. magazine entry latency0.30.42.0-0.6-0.20.1-0.30.4-0.4-0.8-0.20.90.0-1.4
Pavlov. Cond. change in total contacts0.70.72.9-0.40.3-0.40.3-0.20.2-1.2-1.00.90.9-1.7
Pavlov. Cond. index score0.20.30.8-0.7-0.30.3-0.20.4-0.4-0.90.00.40.2-0.8
Pavlov. Cond. latency score0.10.20.8-0.5-0.20.2-0.20.4-0.4-0.50.10.6-0.1-0.9
Pavlov. Cond. lever contacts0.20.20.8-0.2-0.20.1-0.30.5-0.5-0.00.20.7-0.5-0.9
Pavlov. Cond. magazine entry number0.30.41.71.00.3-0.40.2-0.40.41.30.00.0-0.70.9
Pavlov. Cond. intertrial magazine entries0.60.72.30.50.8-0.81.1-1.01.0-0.1-0.70.41.5-0.8
Pavlov. Cond. lever-magazine prob. diff.0.30.41.1-0.9-0.40.3-0.30.6-0.6-1.10.00.50.1-1.0
Pavlov. Cond. response bias0.20.31.0-0.7-0.30.2-0.10.3-0.3-1.0-0.10.10.4-0.8
Pavlov. Cond. lever latency0.40.52.20.80.3-0.20.4-0.30.31.50.50.60.5-1.2
Pavlov. Cond. magazine entry latency2.32.85.4-2.3-1.91.8-2.02.0-2.0-2.20.9-0.7-1.00.0
Pavlov. Cond. change in total contacts0.61.07.2-1.5-0.50.4-0.60.5-0.5-2.7-0.7-0.10.2-0.0
Pavlov. Cond. index score1.11.55.7-1.8-1.00.9-1.21.1-1.1-2.4-0.1-0.5-0.70.6
Pavlov. Cond. latency score0.91.25.0-1.6-0.80.7-1.01.0-1.0-2.2-0.3-0.4-0.70.6
Pavlov. Cond. lever contacts0.40.52.3-0.9-0.30.3-0.40.3-0.3-1.5-0.4-0.5-0.51.1
Pavlov. Cond. magazine entry number3.74.610.33.12.3-2.22.4-2.32.33.2-0.91.41.0-0.6
Pavlov. Cond. intertrial magazine entries0.60.91.71.11.2-1.11.3-1.11.10.8-0.70.80.70.3
Pavlov. Cond. lever-magazine prob. diff.1.41.86.4-2.0-1.21.2-1.41.3-1.3-2.5-0.0-0.6-0.70.7
Pavlov. Cond. response bias1.01.44.5-1.7-1.11.0-1.21.1-1.1-2.10.1-0.6-0.80.7
Time in closed arm before self-admin0.70.92.20.61.1-1.21.1-1.11.1-0.6-1.50.90.8-0.4
Time in closed arm after self-admin0.40.41.31.00.5-0.50.4-0.70.71.1-0.30.5-0.1-0.5
Time in open arm before self-admin1.11.25.80.4-0.80.9-0.70.7-0.72.41.9-0.5-0.70.4
Time in open arm after self-admin0.40.51.5-0.7-0.80.8-0.60.9-0.90.11.2-0.50.00.1
Bone: periosteal estimation0.30.72.00.70.9-1.00.5-0.50.5-0.4-1.41.1-1.0-0.3
Bone: periosteal perimeter0.20.31.00.10.4-0.50.1-0.10.1-0.7-1.00.7-0.90.2
Bone: post-yield work1.92.810.30.41.1-1.40.1-0.50.5-1.4-2.53.2-1.0-2.7
Progressive ratio test 1 active lever presses0.50.61.60.81.1-1.10.8-0.80.8-0.3-1.30.30.4-0.5
Progressive ratio test 1 breakpoint0.50.61.60.71.0-1.10.8-0.80.8-0.4-1.30.30.4-0.4
Progressive ratio test 1 inactive lever presses0.20.30.90.20.5-0.50.6-0.50.5-0.5-0.6-0.41.0-0.1
Progressive ratio test 2 active lever presses3.43.97.71.92.5-2.52.3-2.32.3-0.1-2.81.11.5-0.3
Progressive ratio test 2 breakpoint3.43.97.61.92.5-2.52.3-2.32.3-0.2-2.71.01.5-0.3
Progressive ratio test 2 inactive lever presses6.610.816.13.34.0-4.03.9-3.83.80.6-3.92.33.0-1.0
Incentive Sensitization - Responses0.30.41.50.40.8-0.80.5-0.60.6-0.5-1.20.7-0.10.1
Incentive Sensitization - Breakpoint0.50.61.90.61.0-1.00.7-0.80.8-0.4-1.40.80.10.0
Sum of active levers in priming session hrs 5-62.11.97.9-1.5-0.30.4-0.00.2-0.2-2.8-0.8-1.80.52.6
Progressive ratio0.50.81.8-0.6-0.40.2-1.01.0-1.0-1.0-0.31.1-1.4-0.9
Food seeking constrained by brief footshock0.10.20.4-0.2-0.40.4-0.50.5-0.50.50.4-0.4-0.60.2
Seeking ratio, punishment vs. effort0.60.84.11.00.3-0.10.8-0.70.72.00.6-0.70.80.7
Retroperitoneal fat weight6.527.646.46.86.1-6.06.1-6.06.05.1-4.24.23.1-2.0
Reaction time number correct0.40.72.7-0.6-0.70.7-0.70.7-0.7-0.40.4-1.2-0.71.7
Reaction time mean minus median1.02.47.8-2.3-1.41.3-1.71.5-1.5-2.80.1-1.0-0.90.7
Reaction time mean minus median AUC0.61.64.2-1.8-1.11.1-1.21.2-1.2-2.00.4-1.2-0.51.3
Reaction time num false alarms0.40.64.10.9-0.20.2-0.10.1-0.12.01.00.0-0.4-0.0
Reaction time num false alarms AUC0.40.72.30.1-0.80.8-0.70.8-0.81.51.3-0.4-0.80.2
Reaction time trials correct on left0.40.72.7-0.6-0.70.7-0.70.7-0.7-0.40.4-1.2-0.71.7
Reaction time trials on left0.50.83.1-0.7-0.80.8-0.80.7-0.7-0.50.5-1.3-0.71.8
Reaction time mean0.20.31.4-0.40.2-0.20.2-0.30.3-1.2-0.6-0.20.7-0.2
Reaction time mean AUC0.20.31.4-0.30.4-0.40.3-0.40.4-1.2-0.70.10.8-0.4
Median of all reaction times0.30.50.90.20.7-0.70.7-0.70.7-0.5-0.80.31.0-0.7
Reaction time omissions0.81.22.8-1.5-1.11.1-1.50.9-0.9-1.70.3-1.1-0.80.4
Reaction time false alarm rate0.30.43.20.7-0.10.10.00.1-0.11.80.80.4-0.4-0.4
Reaction time premature initiation rate3.54.88.0-1.9-2.62.6-2.72.4-2.40.12.8-1.8-2.20.9
Reaction time premature initiations3.97.010.1-2.5-3.23.2-3.12.8-2.8-0.53.1-2.6-2.21.8
Std. dev. reaction times0.40.73.7-1.3-0.60.6-0.70.5-0.5-1.9-0.2-0.70.00.1
Reaction time trials completed0.50.83.1-0.7-0.80.8-0.80.7-0.7-0.50.5-1.3-0.71.8
Reaction time trials AUC0.30.62.4-0.5-0.70.7-0.70.6-0.6-0.20.5-1.1-0.71.6
Run reversals in cocaine runway, females0.80.82.10.0-0.70.6-1.00.8-0.81.30.90.8-1.4-0.6
Run reversals in cocaine runway, males0.40.42.80.10.2-0.10.5-0.10.10.50.6-1.00.31.7
Latency to leave start box in cocaine runway0.60.73.50.70.7-0.80.4-0.50.50.2-0.91.3-0.1-1.9
Latency to leave start box in cocaine runway, F0.40.43.50.10.3-0.30.2-0.10.1-0.0-0.40.80.4-1.9
Latency to leave start box in cocaine runway, M0.30.31.20.70.3-0.40.1-0.30.30.3-0.50.6-1.1-0.3
Std. dev. time between licks in bursts0.50.72.20.3-0.70.7-0.80.5-0.51.51.3-0.5-1.00.6
Total sessions with >9 infusions0.40.51.40.70.6-0.70.2-0.50.50.1-0.91.2-0.6-0.9
Short access day 1 total inactive lever presses2.02.75.12.31.9-1.91.6-2.02.01.6-1.31.00.8-0.6
Short access day 10 total inactive lever presses0.20.41.50.80.4-0.40.6-0.60.61.20.2-0.20.70.2
Short access day 1 total infusions1.92.64.32.11.9-1.91.4-1.61.61.2-1.81.90.3-1.1
Short access day 10 total infusions1.72.14.71.71.7-1.81.0-1.21.20.3-2.12.2-0.3-1.3
Short access total infusions1.11.42.71.61.4-1.50.8-1.01.00.8-1.61.5-0.6-0.6
Short access day 1 locomotion1.72.13.11.81.7-1.71.5-1.61.60.9-1.71.50.9-0.1
Short access day 10 total locomotion1.12.04.01.51.8-1.81.4-1.51.50.1-2.01.60.7-0.5
Short access total locomotion2.22.64.51.82.0-2.01.6-1.81.80.4-2.11.70.8-0.8
One hour access (0.3 mA shock)6.06.910.33.13.2-3.23.1-3.23.21.4-2.81.71.9-0.4
Compulsive drug intake3.64.311.2-1.9-2.62.7-2.22.2-2.20.63.3-1.5-1.3-0.2
One hour access (shock baseline)6.910.517.63.44.1-4.03.8-3.83.80.5-4.22.12.5-0.3
Social response proportion0.40.51.3-1.1-0.60.6-0.60.6-0.6-1.10.2-0.6-0.30.9
Social responses0.70.83.2-1.0-0.80.8-0.61.0-1.0-0.50.8-0.9-0.31.8
Social time0.60.81.8-0.9-0.90.9-0.90.8-0.8-0.30.8-1.4-0.61.1
Soleus weight2.98.413.73.73.3-3.23.4-3.33.32.8-1.82.52.1-1.9
Bone: stiffness0.91.45.1-1.5-1.00.8-1.41.2-1.2-2.2-0.30.1-1.3-0.1
Tibialis anterior weight8.027.138.1-6.2-5.65.5-5.75.8-5.8-4.73.9-4.7-4.44.6
Time to tail flick, vehicle, before self-admin0.10.20.6-0.3-0.10.0-0.30.2-0.2-0.5-0.6-0.1-0.80.5
Time to tail flick, vehicle, after self-admin0.81.02.9-0.5-0.80.6-1.01.5-1.50.30.61.0-1.7-0.0
Time to tail flick, test, before self-admin2.02.04.91.81.4-1.51.2-1.21.21.9-0.92.20.3-1.1
Time to tail flick, test, after self-admin0.50.53.7-0.5-0.00.00.10.2-0.2-0.8-0.4-0.6-0.11.9
Delta time to tail flick, vehicle, before/after SA0.70.71.6-0.4-0.80.7-0.91.3-1.30.31.00.5-1.0-0.0
Delta time to tail flick, test, before/after SA2.93.08.3-2.1-1.41.5-0.91.0-1.0-2.40.6-2.90.12.6
Tibia length0.71.910.5-1.8-0.60.6-0.50.7-0.7-3.2-0.8-1.1-0.21.8
Ambulatory time before self-admin0.30.42.9-0.80.1-0.2-0.10.2-0.2-1.7-0.90.60.20.1
Ambulatory time after self-admin0.60.81.90.30.7-0.70.8-0.70.7-0.4-0.71.01.4-1.4
Bone: tissue strength0.10.10.30.10.3-0.30.1-0.30.3-0.3-0.50.40.2-0.6
Total heroin consumption4.04.78.3-2.9-2.42.3-2.42.5-2.5-2.31.4-1.6-1.31.4
Bone: trabecular number0.30.51.8-0.7-0.30.1-0.50.6-0.6-1.3-0.70.7-0.8-0.0
Bone: trabecular spacing0.30.31.70.60.10.00.2-0.20.21.30.70.10.5-0.9
Bone: trabecular thickness0.70.91.61.01.0-1.00.8-0.90.90.4-1.01.30.3-1.2
Bone: trabecular tissue density2.74.06.82.22.3-2.22.6-2.42.41.3-1.61.12.00.1
Water consumed over 24 hours1.11.52.4-1.5-1.51.6-1.31.3-1.3-0.91.4-1.1-0.10.2
Number of responses in last shaping day0.10.10.30.0-0.30.3-0.1-0.00.00.40.6-0.50.10.1