Hub : Genes

Sf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression Sf1 0.17 0.1 5.0e-03 0 -0 -0.01 0 3.1e-01 3.8e-01 9.6e-01 2.4e-01
2 Brain alternative TSS XM_063269208.1 0.03 0.02 4.0e-04 0.03 0.04 0.03 0.03 6.4e-04 2.3e-04 9.1e-04 3.9e-04
3 NAcc alternative TSS XM_063268967.1 0.02 0.01 1.2e-03 0.01 0.01 0.01 0.01 4.0e-02 1.3e-02 2.2e-02 2.7e-02
4 LHb gene expression Sf1 0.2 0.12 1.3e-03 0.13 0.09 0.04 0.08 5.5e-04 3.5e-03 4.3e-02 7.3e-03
5 Brain alternative TSS XM_063268967.1 0.02 0.02 9.0e-03 0.02 0.02 0.01 0.01 7.5e-03 8.2e-03 7.0e-02 1.3e-02
6 Brain alternative TSS XM_063269208.1 0.03 0.02 4.1e-04 0.04 0.04 0.03 0.03 8.7e-05 2.3e-04 8.6e-04 3.4e-04
7 Adipose alternative TSS XM_063268843.1 0.07 0.04 5.0e-05 0 0.03 0.02 0.01 1.0e-01 8.6e-04 3.6e-03 1.8e-02
8 Brain isoform ratio XM_063268967.1 0.04 0.03 2.4e-03 0 0.01 0.01 0 3.4e-01 8.6e-02 3.7e-02 1.3e-01
9 NAcc gene expression Sf1 0.02 0.02 9.9e-03 0.01 0.01 0.01 0.01 3.6e-02 1.7e-02 4.4e-03 3.7e-02
10 PL gene expression Sf1 0.02 0.02 1.0e-02 0.01 0.01 0.02 0.01 2.0e-02 8.0e-03 5.5e-03 1.6e-02
11 PL alternative TSS XM_063268967.1 0.4 0.28 8.0e-03 0.02 0.01 0.04 0.03 6.6e-03 2.4e-02 4.4e-05 5.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.20.41.4-0.4-0.30.10.6-0.70.7-0.50.3-1.01.20.5
Area under the delay curve0.10.20.7-0.1-0.20.10.2-0.40.40.6-0.5-0.8-0.00.6
BMI with tail0.93.310.7-1.3-1.20.72.2-2.42.4-1.0-0.2-2.13.30.4
BMI without tail0.42.13.8-0.9-1.31.11.8-1.91.90.1-1.2-1.12.01.3
Body weight1.98.217.4-2.9-2.92.63.6-3.73.7-1.8-1.80.94.2-1.5
Weight adjusted by age0.71.93.1-1.7-1.31.31.4-1.41.4-1.5-0.61.51.0-1.8
Bone surface1.93.68.9-2.5-1.71.52.2-2.12.1-3.0-0.10.52.3-0.8
Bone volume0.51.04.6-1.2-0.50.30.9-0.90.9-2.10.8-0.41.3-0.2
Breakpoint value in progressive ratio session1.32.44.9-2.2-1.71.61.6-1.91.9-2.0-0.90.80.8-0.6
Number of licking bursts0.10.20.6-0.6-0.40.40.4-0.40.4-0.8-0.00.10.2-0.0
Context. condit. distance diff. score1.01.22.71.41.2-1.1-1.31.0-1.01.60.2-1.1-0.80.4
Locomotion velocity, session 10.40.41.00.2-0.50.50.5-0.40.40.8-1.01.00.8-0.6
Locomotion distance, session 10.40.52.20.0-0.60.51.1-0.70.70.4-0.5-0.31.50.6
Locomotion velocity, session 21.51.93.4-1.3-1.51.41.9-1.71.7-0.9-0.90.11.80.1
Locomotion distance, session 20.50.72.1-0.3-0.90.81.3-1.01.00.3-0.7-0.21.40.7
Locomotion velocity, session 30.60.71.61.30.7-0.8-0.10.5-0.51.20.5-0.91.20.7
Locomotion distance, session 30.00.00.20.30.1-0.1-0.00.0-0.00.4-0.10.10.3-0.4
Stereotopy head waving bouts, day 30.91.03.01.50.9-1.0-0.40.7-0.71.70.6-1.01.30.2
Stereotopy head waving duration, day 30.70.91.71.31.0-1.1-0.81.0-1.01.00.9-1.00.30.6
Locomotion velocity, session 71.01.13.51.21.0-1.1-0.50.8-0.80.91.1-1.90.31.2
Locomotion distance, session 70.20.31.50.6-0.0-0.10.3-0.10.11.2-0.1-0.71.00.2
Stereotopy head waving bouts, day 70.30.30.8-0.00.6-0.7-0.60.5-0.5-0.70.9-0.8-0.4-0.2
Stereotopy head waving duration, day 70.30.42.0-1.0-0.30.20.3-0.50.5-1.40.2-0.50.00.0
Locomotion velocity, session 81.82.25.0-0.8-1.41.41.4-1.41.40.2-1.71.51.6-2.2
Locomotion distance, session 80.30.41.01.00.7-0.8-0.40.4-0.41.00.3-1.00.60.1
Degree of sensitization distance0.20.31.10.50.2-0.30.2-0.00.00.70.2-0.81.00.3
Degree of sensitization stereotypy0.30.32.2-0.8-0.0-0.00.0-0.10.1-1.50.5-0.3-0.3-0.0
Conditioned locomotion1.31.52.5-1.2-1.31.31.6-1.31.3-0.7-1.11.01.5-0.6
Cocaine response after cond. corrected0.50.83.91.30.8-0.8-0.70.7-0.72.00.1-0.40.3-0.3
Cocaine response after cond. not corrected0.40.62.81.10.7-0.7-0.60.5-0.51.70.2-0.30.4-0.5
Cocaine response before conditioning0.40.52.1-1.0-0.60.50.4-0.60.6-1.50.30.4-0.1-0.3
Saline control response4.05.57.5-2.4-2.62.52.7-2.72.7-1.2-2.01.72.3-2.6
Bone: connectivity density1.11.83.4-1.5-1.31.11.6-1.71.7-1.4-0.3-0.21.9-0.3
Bone: cortical apparent density0.20.30.9-0.7-0.50.60.3-0.30.3-0.4-0.70.5-0.90.3
Bone: cortical area0.40.61.5-0.9-0.60.60.7-0.70.7-1.2-0.00.40.8-1.0
Bone: cortical porosity0.30.32.0-0.3-0.30.20.4-0.30.3-0.3-0.3-0.60.11.4
Bone: cortical porosity0.50.51.1-0.7-0.70.70.8-0.80.8-0.5-0.7-0.40.61.0
Bone: cortical thickness3.05.07.2-2.5-2.62.72.4-2.42.4-1.3-2.42.31.2-1.9
Bone: cortical thickness1.31.53.3-0.8-1.41.51.2-1.31.30.6-1.81.60.8-0.6
Bone: cortical tissue density0.30.40.9-0.8-0.70.80.5-0.50.5-0.5-0.90.7-0.80.3
Condit. Reinf. active minus inactive responses0.20.20.4-0.4-0.40.40.5-0.60.6-0.1-0.5-0.4-0.00.7
Condit. Reinf. active-inactive response ratio0.10.20.6-0.5-0.30.40.2-0.30.3-0.2-0.5-0.1-0.80.4
Condit. Reinf. active responses0.20.21.20.10.2-0.2-0.0-0.00.0-0.00.2-1.00.01.1
Condit. Reinf. inactive responses0.50.71.90.80.9-1.0-0.50.6-0.60.21.1-1.40.51.0
Incentive salience index mean0.30.41.6-0.4-0.40.30.6-0.70.7-0.1-0.4-0.80.51.3
Condit. Reinf. lever presses0.20.30.8-0.4-0.20.10.4-0.50.5-0.70.2-0.70.90.7
Condit. Reinf. active minus inactive responses0.30.40.90.30.7-0.8-0.70.8-0.8-0.60.9-0.5-0.60.2
Condit. Reinf. active-inactive response ratio1.21.94.21.21.7-1.8-1.51.6-1.6-0.42.0-1.3-0.50.4
Condit. Reinf. active responses0.10.10.6-0.40.0-0.1-0.00.1-0.1-0.80.2-0.3-0.50.4
Condit. Reinf. inactive responses0.60.82.0-1.0-1.11.11.0-1.11.1-0.2-1.40.20.00.4
Condit. Reinf. lever presses0.71.14.5-1.5-0.80.71.0-0.80.8-2.10.10.70.7-0.6
Condit. Reinf. lever reinforcers received0.10.21.3-0.7-0.30.20.2-0.20.2-1.10.00.1-0.40.1
Conditioned reinforcement - actives0.31.03.20.00.8-0.8-0.60.8-0.8-1.81.80.7-0.3-1.3
Conditioned reinforcement - inactives1.54.26.81.82.5-2.4-2.62.4-2.4-0.32.6-0.7-2.2-0.4
Conditioned locomotion5.88.714.43.23.5-3.4-3.53.8-3.81.13.1-1.1-3.00.1
Patch foraging indifference point 0 sec0.00.10.20.30.2-0.2-0.30.2-0.20.10.2-0.5-0.30.0
Patch foraging indifference point AUC0.92.25.6-2.1-1.41.41.3-1.41.4-2.4-0.71.50.1-1.1
Delay disc. indifference point, 0s delay0.20.31.40.60.1-0.2-0.1-0.30.31.2-0.2-0.90.10.4
Delay disc. indifference point, 16s delay0.81.12.40.81.0-1.0-0.91.1-1.10.30.8-1.4-1.11.5
Delay disc. indifference point, 2s delay0.20.20.50.30.4-0.5-0.4-0.00.00.30.5-0.60.1-0.7
Delay disc. indifference point, 24s delay0.10.20.7-0.1-0.40.40.2-0.20.20.7-0.80.1-0.1-0.3
Delay disc. indifference point, 4s delay0.40.41.40.1-0.30.30.3-0.70.71.2-0.9-0.70.2-0.2
Delay disc. indifference point, 8s delay0.20.30.8-0.0-0.40.40.4-0.50.50.9-0.9-0.40.30.7
Indifference point function ln k2.26.616.43.72.6-2.6-2.62.7-2.74.11.2-2.2-1.01.0
Indifference point function log k2.26.616.43.72.6-2.6-2.62.7-2.74.11.2-2.2-1.01.0
Patch foraging total patch changes 0 sec0.00.00.10.2-0.10.2-0.0-0.10.10.3-0.3-0.0-0.1-0.4
Patch foraging total patch changes 12 sec2.83.76.1-2.5-2.22.22.3-2.22.2-2.0-1.51.31.1-0.9
Patch foraging total patch changes 18 sec0.20.51.4-0.9-0.60.60.6-0.90.9-1.2-0.2-0.10.1-0.4
Patch foraging total patch changes 24 sec0.82.75.4-1.8-1.71.71.5-1.71.7-1.5-1.31.80.7-2.3
Patch foraging total patch changes 6 sec0.71.11.8-1.0-1.31.21.3-1.31.3-0.4-1.10.51.0-0.9
Patch foraging time to switch 0 sec0.31.02.2-1.1-0.60.41.1-1.01.0-1.50.3-0.91.31.3
Patch foraging water rate 0 sec0.82.94.72.11.8-1.6-2.22.0-2.01.90.6-0.1-1.9-0.6
Patch foraging water rate 12 sec1.45.513.43.32.3-2.1-2.82.7-2.73.70.3-0.5-1.8-0.7
Patch foraging water rate 18 sec0.81.96.92.11.3-1.2-1.31.5-1.52.60.1-0.5-0.2-0.3
Patch foraging water rate 24 sec1.62.35.52.11.6-1.5-1.81.6-1.62.30.5-0.5-0.8-1.0
Patch foraging water rate 6 sec1.72.49.82.51.4-1.2-1.51.6-1.63.1-0.2-0.3-0.7-0.0
Seeking ratio, delayed vs. immediate footshock0.40.53.20.50.4-0.4-0.20.3-0.30.50.2-1.2-0.41.8
Distance traveled before self-admin0.20.42.3-0.9-0.20.20.4-0.50.5-1.50.5-0.30.10.3
Distance traveled after self-admin0.20.30.9-0.8-0.40.40.3-0.30.3-1.0-0.3-0.0-0.70.6
Extensor digitorum longus weight5.220.730.4-5.3-5.14.95.5-5.55.5-3.6-3.72.84.6-1.9
Bone: elastic displacement0.40.52.60.80.10.1-0.40.4-0.41.6-0.90.7-0.2-0.6
Bone: elastic work1.72.24.8-1.0-1.71.71.6-1.61.60.5-2.21.41.4-0.7
Bone: endosteal estimation1.23.05.82.01.9-2.1-1.41.5-1.50.92.1-2.40.81.5
Bone: endosteal perimeter1.74.28.52.22.5-2.7-2.02.0-2.00.32.9-2.50.31.1
Epididymis fat weight1.99.715.33.53.9-3.9-3.83.7-3.71.33.5-2.4-1.70.5
Delta time in closed arm before/after self-admin1.21.12.2-0.1-1.11.11.1-0.90.91.4-1.50.71.4-0.1
Delta time in open arm before/after self-admin0.40.53.5-0.90.1-0.1-0.3-0.20.2-1.90.50.2-0.9-0.3
Diff in mean of infusions in LGA sessions0.40.81.4-1.0-1.01.00.8-0.90.9-0.5-0.80.90.7-1.2
Delay discount exponential model param0.10.20.40.20.3-0.3-0.20.5-0.5-0.50.60.60.0-0.3
Extinction: sum of active levers before priming1.01.42.6-1.5-1.31.21.4-1.61.6-1.3-0.50.30.9-0.4
Active lever presses in extinction session 62.32.35.5-2.0-1.31.21.4-1.51.5-2.4-0.21.21.2-1.7
Bone: final force1.32.13.5-1.7-1.51.41.8-1.61.6-1.6-0.60.81.9-0.5
Bone: final moment1.22.03.4-1.6-1.51.41.7-1.61.6-1.5-0.60.81.8-0.5
Food consumed during 24 hour testing period0.20.52.2-0.5-0.00.1-0.10.2-0.2-1.00.40.9-0.6-1.5
Glucose2.43.86.62.62.1-2.2-1.71.7-1.72.01.7-2.5-0.11.7
Heart weight1.21.95.81.80.9-1.1-0.50.3-0.32.40.4-2.41.31.5
Delay discount hyperbolic model param0.10.10.50.20.2-0.2-0.20.5-0.5-0.50.40.70.0-0.1
Intermittent access intake day 1-15 change0.42.03.21.01.6-1.6-1.81.7-1.7-0.41.8-0.2-1.6-1.0
Intermittent access intake escalation0.31.93.20.81.6-1.5-1.71.6-1.6-0.61.80.0-1.6-1.1
Intermittent access intake escalation 21.01.62.70.81.5-1.4-1.61.5-1.5-0.61.60.0-1.5-0.9
Intermitt. access day 1 inactive lever presses0.00.31.30.30.4-0.4-0.60.7-0.7-0.10.20.4-1.10.2
Intermitt. access day 15 inactive lever presses0.63.45.11.82.3-2.2-2.02.3-2.3-0.02.2-1.0-1.51.0
Intermitt. access escalation Index0.92.95.71.91.6-1.6-1.81.6-1.61.81.0-2.4-1.41.6
Intermittent access day 1 total infusions1.75.28.82.62.8-2.9-2.12.3-2.30.93.0-2.7-0.51.4
Intermittent access day 15 total infusions3.48.314.93.03.7-3.7-3.33.4-3.40.43.9-1.7-1.9-0.1
Intermittent access terminal intake (last 3 days)4.37.515.52.83.6-3.6-3.13.0-3.00.23.9-1.9-1.5-0.2
Intermittent access total infusions5.26.111.92.83.2-3.3-2.62.7-2.70.53.5-2.2-0.90.6
Intermittent access day 1 locomotion1.83.25.42.12.2-2.3-1.81.9-1.90.82.3-1.9-0.70.7
Intermittent access day 15 total locomotion1.97.414.22.53.4-3.5-3.13.1-3.1-0.23.8-1.8-2.10.1
Intermittent access total locomotion9.010.920.43.34.1-4.2-3.63.6-3.60.24.5-2.9-2.11.0
Intermittent access standard deviation0.31.62.81.31.6-1.5-1.71.6-1.60.31.30.3-1.2-0.6
Left kidney weight0.32.54.01.71.9-2.0-1.91.5-1.50.81.8-1.8-1.00.3
Right kidney weight0.21.11.91.21.4-1.4-1.31.2-1.20.41.3-0.5-0.6-0.5
Cocaine induced anxiety0.00.10.7-0.10.1-0.1-0.10.1-0.1-0.80.50.3-0.3-0.4
Post-drug Anxiety0.40.40.9-0.7-0.60.50.7-0.50.5-1.0-0.00.70.8-0.6
Baseline Anxiety0.40.71.4-0.6-1.01.00.9-0.70.70.5-1.20.91.0-0.6
Tail length0.63.15.3-1.7-2.02.11.8-1.81.8-0.3-2.32.30.8-1.2
Length with tail2.08.811.2-3.0-3.33.33.3-3.23.2-1.3-3.03.22.8-2.4
Length without tail1.47.18.9-2.5-3.02.93.0-2.82.8-0.9-2.72.82.9-2.4
Times rat made contact with spout0.60.71.7-0.8-1.11.11.0-1.01.0-0.1-1.30.20.20.6
Lifetime Intake3.54.37.72.52.6-2.7-2.12.2-2.20.82.8-1.9-0.60.7
Liver weight, left0.40.72.41.30.8-0.9-0.80.7-0.71.50.1-0.30.3-0.3
Liver weight, right1.12.07.92.21.2-1.2-1.31.2-1.22.80.1-0.40.3-1.0
Locomotor activity0.81.25.71.60.9-0.8-1.11.0-1.02.4-0.30.2-0.4-0.5
Locomotor testing distance0.61.68.41.80.9-0.7-1.01.0-1.02.9-0.70.4-0.3-0.7
Locomotor testing rearing0.41.46.91.80.9-0.8-1.11.1-1.12.6-0.60.1-0.5-0.2
Locomotion in novel chamber4.45.98.92.83.0-2.9-2.83.0-3.01.32.7-1.7-1.60.5
Locomotion in novel chamber post-restriction1.54.45.82.12.4-2.4-2.42.4-2.40.82.2-1.6-2.01.8
Fecal boli incidents, locomotor time 10.20.52.1-0.30.5-0.5-0.70.2-0.2-1.41.1-0.1-0.7-0.5
Change in fecal boli incidents, locomotor task0.50.52.00.5-0.20.20.7-0.20.21.4-0.7-0.41.20.6
Time >=10cm from walls, locomotor time 11.92.35.91.11.8-2.0-1.51.3-1.3-0.52.4-2.1-0.50.8
Bouts of movement, locomotor time 11.31.73.7-1.9-1.31.41.5-1.01.0-1.9-1.01.0-0.91.0
Total resting periods, locomotor time 10.91.13.5-1.5-0.91.01.0-0.70.7-1.9-0.40.5-1.01.0
Rest time, locomotor task time 10.91.42.21.31.4-1.4-1.31.5-1.50.41.0-0.8-1.20.6
Distance moved, locomotor task time 10.10.20.6-0.3-0.30.20.2-0.60.60.2-0.1-0.50.7-0.2
Vertical activity count, locomotor time 10.10.71.31.10.9-0.9-0.90.9-0.91.10.5-0.3-0.3-0.2
Time >=10cm from walls, locomotor time 20.10.42.0-0.40.3-0.3-0.30.3-0.3-1.40.7-0.3-0.80.3
Bouts of movement, locomotor time 20.20.51.4-1.0-0.70.80.8-0.50.5-0.8-0.70.1-0.51.2
Total resting periods, locomotor time 20.10.42.1-0.6-0.40.40.5-0.20.2-0.6-0.4-0.2-0.61.4
Rest time, locomotor task time 21.72.94.52.11.8-1.8-1.51.9-1.91.31.2-1.6-1.12.1
Distance moved, locomotor task time 21.21.62.6-1.6-1.41.41.2-1.31.3-1.0-1.01.30.6-1.6
Vertical activity count, locomotor time 20.30.83.7-0.3-0.60.70.4-0.40.40.6-0.91.60.4-1.9
Light reinforcement 10.00.10.90.20.10.0-0.40.4-0.40.1-0.30.2-0.9-0.0
Light reinforcement 21.02.44.81.31.7-1.7-1.72.1-2.1-0.72.2-0.5-1.0-0.1
Bone: marrow area1.33.26.52.12.0-2.2-1.51.5-1.51.12.1-2.50.81.7
Bone: maximum diameter0.30.62.0-0.30.3-0.4-0.10.2-0.2-1.41.10.10.8-1.4
Bone: maximum force1.22.35.3-1.8-1.31.11.9-1.71.7-2.20.00.22.3-0.2
Bone: maximum moment1.12.25.0-1.7-1.31.11.8-1.71.7-2.0-0.10.12.2-0.2
Mean time between licks in bursts0.21.32.6-0.4-1.31.31.4-1.21.21.0-1.60.81.3-0.6
Mean num. licks in bursts0.10.10.70.30.00.0-0.10.1-0.10.8-0.5-0.1-0.40.5
Cd content in liver1.71.93.30.71.6-1.5-1.81.5-1.5-0.41.6-1.0-1.80.9
Co content in liver0.60.72.40.50.10.1-0.60.4-0.41.5-1.30.5-1.5-0.2
Cu content in liver0.20.31.00.00.2-0.1-0.20.1-0.1-0.10.0-1.0-0.91.0
Fe content in liver0.70.85.4-0.4-0.40.40.5-0.40.4-0.1-0.31.21.2-2.3
K content in liver0.70.71.6-0.5-0.70.60.8-1.11.10.3-0.8-0.51.3-0.6
Mg content in liver0.30.31.50.70.2-0.3-0.30.0-0.01.2-0.4-1.10.10.3
Mn content in liver1.92.14.4-1.8-1.41.31.6-1.41.4-2.1-0.41.11.4-1.5
Na content in liver0.60.71.7-0.7-0.80.80.6-0.70.7-0.5-0.91.10.5-1.3
Rb content in liver1.21.44.01.51.1-1.1-1.11.1-1.12.00.1-1.1-0.61.0
Se content in liver0.50.61.60.20.8-0.9-0.80.8-0.8-0.71.3-0.4-0.6-0.8
Sr content in liver2.42.13.1-1.8-1.51.61.4-1.51.5-1.7-0.91.60.6-1.2
Zn content in liver0.30.40.8-0.7-0.80.80.6-0.90.9-0.3-0.6-0.2-0.10.2
Bone: minimum diameter1.53.07.61.71.8-2.0-1.41.4-1.40.71.9-2.80.02.2
Time in familiar zone, hab. session 10.30.31.10.60.6-0.7-0.60.4-0.40.50.5-1.1-0.1-0.4
Time in novel zone, hab. session 10.20.20.90.4-0.20.30.2-0.00.01.0-0.70.90.30.2
Total zone transitions, hab. session 10.30.40.7-0.7-0.70.70.8-0.60.6-0.7-0.70.20.10.3
Total locomotion distance, hab. session 10.40.61.11.00.9-0.9-0.60.8-0.80.60.5-1.10.10.4
Locomotion velocity, hab. session 10.10.10.60.50.4-0.4-0.10.3-0.30.20.1-0.80.10.3
Time in familiar zone, hab. session 20.91.04.3-0.2-0.70.80.5-0.80.81.1-1.20.60.9-2.1
Time in novel zone, hab. session 20.40.53.7-0.00.2-0.3-0.00.3-0.3-0.70.6-0.5-0.51.9
Total zone transitions, hab. session 20.91.12.9-0.5-0.90.71.4-1.11.1-0.3-0.6-0.81.51.7
Total locomotion distance, hab. session 20.50.72.80.80.2-0.40.3-0.00.00.8-0.0-1.51.01.7
Locomotion velocity, hab. session 20.60.83.11.00.6-0.7-0.10.3-0.30.70.4-1.80.81.7
Novel to familiar place preference ratio0.60.74.4-1.4-0.30.30.4-0.40.4-2.10.90.3-0.3-0.1
Novelty place preference0.40.53.0-1.0-0.00.00.0-0.10.1-1.71.00.1-0.60.1
Time in novel zone, NPP test0.30.42.1-0.9-0.10.00.1-0.20.2-1.40.90.2-0.5-0.0
Total zone transitions, NPP test1.11.73.0-1.5-1.41.31.7-1.61.6-1.2-0.90.31.40.6
Total locomotion distance, NPP test0.30.42.50.40.0-0.10.4-0.10.10.4-0.1-0.70.71.6
Locomotion velocity, NPP test0.30.43.30.2-0.0-0.10.3-0.10.10.1-0.1-0.70.41.8
Intraocular pressure1.01.63.90.51.4-1.2-1.71.4-1.4-0.81.40.1-2.0-0.3
Delta distance traveled before/after self-admin0.30.31.30.2-0.30.40.10.0-0.01.1-1.20.5-0.3-0.1
Delta ambulatory time before/after self-admin0.20.41.80.1-0.50.60.3-0.20.21.0-1.40.8-0.10.1
Parametrial fat weight3.37.811.23.23.3-3.3-3.23.1-3.11.53.0-2.8-1.61.5
Pavlov. Cond. lever latency0.20.20.40.50.4-0.3-0.50.6-0.60.30.20.4-0.6-0.7
Pavlov. Cond. magazine entry latency0.30.42.0-0.6-0.20.10.3-0.40.4-0.80.2-0.9-0.01.4
Pavlov. Cond. change in total contacts0.60.72.9-0.40.3-0.4-0.30.2-0.2-1.21.0-0.9-0.91.7
Pavlov. Cond. index score0.20.30.8-0.7-0.30.30.2-0.40.4-0.9-0.0-0.4-0.20.8
Pavlov. Cond. latency score0.10.20.8-0.5-0.20.20.2-0.40.4-0.5-0.1-0.60.10.9
Pavlov. Cond. lever contacts0.20.20.8-0.2-0.20.10.3-0.50.5-0.0-0.2-0.70.50.9
Pavlov. Cond. magazine entry number0.30.41.71.00.3-0.4-0.20.4-0.41.3-0.0-0.00.7-0.9
Pavlov. Cond. intertrial magazine entries0.60.82.30.50.8-0.8-1.11.0-1.0-0.10.7-0.4-1.50.8
Pavlov. Cond. lever-magazine prob. diff.0.30.41.1-0.9-0.40.30.3-0.60.6-1.1-0.0-0.5-0.11.0
Pavlov. Cond. response bias0.20.21.0-0.7-0.30.20.1-0.30.3-1.00.1-0.1-0.40.8
Pavlov. Cond. lever latency0.40.52.20.80.3-0.2-0.40.3-0.31.5-0.5-0.6-0.51.2
Pavlov. Cond. magazine entry latency2.02.85.5-2.3-1.91.82.0-2.02.0-2.2-0.90.71.0-0.0
Pavlov. Cond. change in total contacts0.41.07.2-1.6-0.50.40.6-0.50.5-2.70.70.1-0.20.0
Pavlov. Cond. index score0.91.55.7-1.8-1.00.91.2-1.11.1-2.40.10.50.7-0.6
Pavlov. Cond. latency score0.71.25.0-1.6-0.80.71.0-1.01.0-2.20.30.40.7-0.6
Pavlov. Cond. lever contacts0.30.52.3-0.9-0.30.30.4-0.30.3-1.50.40.50.5-1.1
Pavlov. Cond. magazine entry number3.54.610.33.12.3-2.2-2.42.3-2.33.20.9-1.4-1.00.6
Pavlov. Cond. intertrial magazine entries0.40.91.71.11.2-1.1-1.31.1-1.10.80.7-0.8-0.7-0.3
Pavlov. Cond. lever-magazine prob. diff.1.21.86.4-2.0-1.21.21.4-1.31.3-2.50.00.60.7-0.7
Pavlov. Cond. response bias1.01.44.5-1.7-1.11.01.2-1.11.1-2.1-0.10.60.8-0.7
Time in closed arm before self-admin0.50.92.20.61.1-1.2-1.11.1-1.1-0.61.5-0.9-0.80.4
Time in closed arm after self-admin0.30.41.31.00.5-0.5-0.40.7-0.71.10.3-0.50.10.5
Time in open arm before self-admin1.01.25.80.4-0.80.90.7-0.70.72.4-1.90.50.7-0.4
Time in open arm after self-admin0.40.51.5-0.7-0.80.80.6-0.90.90.1-1.20.5-0.0-0.1
Bone: periosteal estimation0.30.72.00.60.9-1.0-0.50.5-0.5-0.41.4-1.11.00.3
Bone: periosteal perimeter0.20.31.00.10.4-0.5-0.10.1-0.1-0.71.0-0.70.9-0.2
Bone: post-yield work1.62.810.30.41.1-1.4-0.10.5-0.5-1.42.5-3.21.02.7
Progressive ratio test 1 active lever presses0.40.61.60.81.1-1.1-0.80.8-0.8-0.31.3-0.3-0.40.5
Progressive ratio test 1 breakpoint0.40.61.60.71.0-1.1-0.80.8-0.8-0.41.3-0.3-0.40.4
Progressive ratio test 1 inactive lever presses0.10.30.90.20.5-0.5-0.60.5-0.5-0.50.60.4-1.00.1
Progressive ratio test 2 active lever presses2.83.97.71.92.5-2.5-2.32.3-2.3-0.12.8-1.1-1.50.3
Progressive ratio test 2 breakpoint3.03.97.61.92.5-2.5-2.32.3-2.3-0.22.7-1.0-1.50.3
Progressive ratio test 2 inactive lever presses3.410.816.13.34.0-4.0-3.93.8-3.80.63.9-2.3-3.01.0
Incentive Sensitization - Responses0.20.41.50.40.8-0.8-0.50.6-0.6-0.51.2-0.70.1-0.1
Incentive Sensitization - Breakpoint0.30.61.90.61.0-1.0-0.70.8-0.8-0.41.4-0.8-0.1-0.0
Sum of active levers in priming session hrs 5-62.11.97.9-1.5-0.30.40.0-0.20.2-2.80.81.8-0.5-2.6
Progressive ratio0.30.81.8-0.6-0.40.21.0-1.01.0-1.00.3-1.11.40.9
Food seeking constrained by brief footshock0.10.20.4-0.2-0.40.40.5-0.50.50.5-0.40.40.6-0.2
Seeking ratio, punishment vs. effort0.40.84.11.00.3-0.1-0.80.7-0.72.0-0.60.7-0.8-0.7
Retroperitoneal fat weight6.227.646.46.86.1-6.0-6.16.0-6.05.14.2-4.2-3.12.0
Reaction time number correct0.20.72.7-0.6-0.70.70.7-0.70.7-0.4-0.41.20.7-1.7
Reaction time mean minus median0.42.47.8-2.3-1.41.31.7-1.51.5-2.8-0.11.00.9-0.7
Reaction time mean minus median AUC0.21.64.2-1.8-1.11.11.2-1.21.2-2.0-0.41.20.5-1.3
Reaction time num false alarms0.30.64.10.9-0.20.20.1-0.10.12.0-1.0-0.00.40.0
Reaction time num false alarms AUC0.30.72.30.1-0.80.80.7-0.80.81.5-1.30.40.8-0.2
Reaction time trials correct on left0.20.72.7-0.6-0.70.70.7-0.70.7-0.4-0.41.20.7-1.7
Reaction time trials on left0.20.83.1-0.7-0.80.80.8-0.70.7-0.5-0.51.30.7-1.8
Reaction time mean0.10.21.4-0.40.2-0.2-0.20.3-0.3-1.20.60.2-0.70.2
Reaction time mean AUC0.10.31.4-0.30.4-0.4-0.30.4-0.4-1.20.7-0.1-0.80.4
Median of all reaction times0.30.50.90.20.7-0.7-0.70.7-0.7-0.50.8-0.3-1.00.7
Reaction time omissions0.81.22.8-1.5-1.11.11.5-0.90.9-1.7-0.31.10.8-0.4
Reaction time false alarm rate0.30.43.20.7-0.10.1-0.0-0.10.11.8-0.8-0.40.40.4
Reaction time premature initiation rate3.14.88.0-1.9-2.62.62.7-2.42.40.1-2.81.82.2-0.9
Reaction time premature initiations2.37.010.1-2.5-3.23.23.1-2.82.8-0.5-3.12.62.2-1.8
Std. dev. reaction times0.20.73.7-1.3-0.60.60.7-0.50.5-1.90.20.7-0.0-0.1
Reaction time trials completed0.20.83.1-0.7-0.80.80.8-0.70.7-0.5-0.51.30.7-1.8
Reaction time trials AUC0.20.62.4-0.5-0.70.70.7-0.60.6-0.2-0.51.10.7-1.6
Run reversals in cocaine runway, females0.70.82.1-0.0-0.70.61.0-0.80.81.3-0.9-0.81.40.6
Run reversals in cocaine runway, males0.40.42.80.10.2-0.1-0.50.1-0.10.5-0.61.0-0.3-1.7
Latency to leave start box in cocaine runway0.50.73.50.70.7-0.8-0.40.5-0.50.20.9-1.30.11.9
Latency to leave start box in cocaine runway, F0.30.43.50.10.3-0.3-0.20.1-0.1-0.00.4-0.8-0.41.9
Latency to leave start box in cocaine runway, M0.30.31.20.70.3-0.4-0.10.3-0.30.30.5-0.61.10.3
Std. dev. time between licks in bursts0.40.72.20.3-0.70.70.8-0.50.51.5-1.30.51.0-0.6
Total sessions with >9 infusions0.40.51.40.70.6-0.7-0.20.5-0.50.10.9-1.20.60.9
Short access day 1 total inactive lever presses1.32.65.12.31.9-1.9-1.62.0-2.01.61.3-1.0-0.80.6
Short access day 10 total inactive lever presses0.10.41.50.80.4-0.4-0.60.6-0.61.2-0.20.2-0.7-0.2
Short access day 1 total infusions1.32.64.32.11.9-1.9-1.41.6-1.61.21.8-1.9-0.31.1
Short access day 10 total infusions1.32.14.71.61.7-1.8-1.01.2-1.20.32.1-2.20.31.3
Short access total infusions1.01.42.61.61.4-1.5-0.81.0-1.00.81.6-1.50.60.6
Short access day 1 locomotion1.32.13.11.81.7-1.7-1.51.6-1.60.91.7-1.5-0.90.1
Short access day 10 total locomotion0.52.04.01.51.8-1.8-1.41.5-1.50.12.0-1.6-0.70.5
Short access total locomotion1.72.64.51.82.0-2.0-1.61.8-1.80.42.1-1.7-0.80.8
One hour access (0.3 mA shock)5.86.910.33.13.2-3.2-3.13.2-3.21.42.8-1.7-1.90.4
Compulsive drug intake2.94.311.2-1.9-2.62.72.2-2.22.20.6-3.31.51.30.2
One hour access (shock baseline)4.010.517.63.44.1-4.0-3.83.8-3.80.54.2-2.1-2.50.3
Social response proportion0.40.51.3-1.1-0.60.60.6-0.60.6-1.1-0.20.60.3-0.9
Social responses0.60.83.2-1.0-0.80.80.6-1.01.0-0.5-0.80.90.3-1.8
Social time0.50.81.8-0.9-0.90.90.9-0.80.8-0.3-0.81.40.6-1.1
Soleus weight2.98.413.83.73.3-3.2-3.43.3-3.32.81.8-2.5-2.11.9
Bone: stiffness0.81.45.1-1.5-1.00.81.4-1.21.2-2.20.3-0.11.30.1
Tibialis anterior weight7.927.238.3-6.2-5.65.55.7-5.85.8-4.7-3.94.74.4-4.6
Time to tail flick, vehicle, before self-admin0.10.20.6-0.3-0.10.00.3-0.20.2-0.50.60.10.8-0.5
Time to tail flick, vehicle, after self-admin0.51.02.9-0.5-0.80.61.0-1.51.50.3-0.6-1.01.70.0
Time to tail flick, test, before self-admin1.82.04.91.81.4-1.5-1.21.2-1.21.90.9-2.2-0.31.1
Time to tail flick, test, after self-admin0.40.53.7-0.5-0.00.0-0.1-0.20.2-0.80.40.60.1-1.9
Delta time to tail flick, vehicle, before/after SA0.60.71.6-0.5-0.80.70.9-1.31.30.3-1.0-0.51.00.0
Delta time to tail flick, test, before/after SA2.43.08.3-2.1-1.41.50.9-1.01.0-2.4-0.62.9-0.1-2.6
Tibia length0.71.910.5-1.8-0.60.60.5-0.70.7-3.20.81.10.2-1.8
Ambulatory time before self-admin0.10.42.9-0.80.1-0.20.1-0.20.2-1.70.9-0.6-0.2-0.1
Ambulatory time after self-admin0.50.81.90.30.7-0.7-0.80.7-0.7-0.40.7-1.0-1.41.4
Bone: tissue strength0.10.10.30.10.3-0.3-0.10.3-0.3-0.30.5-0.4-0.20.6
Total heroin consumption4.04.78.3-2.9-2.42.32.4-2.52.5-2.3-1.41.61.3-1.4
Bone: trabecular number0.20.51.8-0.8-0.30.10.5-0.60.6-1.30.7-0.70.80.0
Bone: trabecular spacing0.20.31.70.60.10.0-0.20.2-0.21.3-0.7-0.1-0.50.9
Bone: trabecular thickness0.60.91.61.01.0-1.0-0.80.9-0.90.41.0-1.3-0.31.2
Bone: trabecular tissue density2.34.06.82.22.3-2.2-2.62.4-2.41.31.6-1.1-2.0-0.1
Water consumed over 24 hours0.71.52.4-1.5-1.51.61.3-1.31.3-0.9-1.41.10.1-0.2
Number of responses in last shaping day0.10.10.30.0-0.30.30.10.0-0.00.4-0.60.5-0.1-0.1