Hub : Genes

Tm2d1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative TSS NM_001108670.2 0.11 0.11 1.3e-05 0.03 0.03 0.03 0.03 5.4e-06 5.0e-06 1.0e-05 9.1e-06
2 RMTg intron excision ratio chr5_118170283_118177265 0.14 0.12 2.2e-03 0.06 0.06 0.06 0.05 8.6e-03 9.6e-03 1.0e-02 2.1e-02
3 Brain isoform ratio NM_001108670.2 0.06 0.06 1.2e-04 0.05 0.04 0.05 0.05 4.2e-05 7.5e-05 4.0e-05 4.0e-05
4 IC isoform ratio NM_001108670.2 0.09 0.07 8.5e-04 0.02 0.01 -0 0.01 5.9e-02 7.8e-02 3.5e-01 1.3e-01
5 PL alternative TSS NM_001108670.2 0.02 0.03 9.1e-03 0.02 0.01 0.01 0.02 2.9e-03 1.2e-02 2.2e-02 5.2e-03
6 PL alternative TSS NM_001108670.2 0.04 0.03 2.2e-04 0.04 0.03 0.03 0.04 6.7e-05 2.3e-04 1.2e-04 1.0e-04
7 PL alternative TSS XM_063287946.1 0.03 0.03 4.0e-04 0.03 0.03 0.03 0.03 1.4e-04 4.8e-04 2.6e-04 2.1e-04
8 PL isoform ratio NM_001108670.2 0.04 0.03 2.0e-04 0.04 0.03 0.03 0.04 4.0e-05 1.5e-04 1.1e-04 5.9e-05
9 IC isoform ratio XM_063287945.1 0.06 0.05 9.4e-03 0.01 0.02 -0 0.01 1.0e-01 5.2e-02 3.7e-01 1.6e-01
10 Brain alternative TSS NM_001108670.2 0.04 0.04 1.6e-03 0.03 0.03 0.03 0.03 9.2e-04 1.6e-03 1.7e-03 1.2e-03
11 NAcc isoform ratio NM_001108670.2 0.04 0.05 1.0e-04 0.03 0.03 0.03 0.03 4.8e-05 8.2e-05 5.8e-05 8.1e-05
12 Brain alternative TSS XM_063287946.1 0.04 0.04 1.7e-03 0.03 0.03 0.03 0.03 1.0e-03 1.6e-03 1.9e-03 1.2e-03
13 BLA intron excision ratio chr5_118166635_118177265 0.06 0.06 4.5e-03 0.01 0.02 0.02 0.02 6.4e-02 1.9e-02 3.9e-02 4.3e-02
14 Brain intron excision ratio chr5_118166635_118177265 0.04 0.04 6.6e-04 0.02 0.03 0.02 0.02 7.9e-03 4.7e-04 4.1e-03 5.5e-03
15 NAcc alternative TSS XM_063287946.1 0.1 0.1 3.2e-05 0.03 0.03 0.03 0.03 1.0e-05 1.3e-05 1.6e-05 1.5e-05
16 IC alternative TSS XM_063287946.1 0.1 0.08 7.1e-04 0.02 0.04 0.01 0.03 4.1e-02 1.1e-02 1.2e-01 2.5e-02
17 IC alternative TSS NM_001108670.2 0.1 0.08 1.4e-03 0.03 0.03 0.01 0.02 3.0e-02 2.3e-02 1.5e-01 3.5e-02
18 Brain alternative TSS NM_001108670.2 0.04 0.04 5.3e-04 0.04 0.03 0.03 0.03 2.1e-04 4.1e-04 4.7e-04 3.9e-04
19 pVTA intron excision ratio chr5_118166635_118177265 0.04 0.03 3.6e-03 0.01 0.02 0.02 0.01 5.2e-02 6.0e-03 1.7e-02 4.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.40.70.80.8-0.7-0.8-0.8-0.9-0.90.9-0.9-0.9-0.8-0.80.8-0.9-0.90.8-0.90.9-0.9-0.9
Area under the delay curve0.81.31.81.2-1.3-1.2-1.1-0.9-0.90.9-0.9-1.1-1.3-1.31.3-1.1-1.11.3-1.01.0-1.3-1.0
BMI with tail0.62.32.8-1.61.61.71.41.31.3-1.31.31.51.61.6-1.61.51.5-1.61.5-1.51.71.5
BMI without tail0.63.43.9-1.81.81.91.82.02.0-2.02.01.91.71.7-1.71.91.9-1.81.9-1.91.81.9
Body weight0.10.40.6-0.40.60.50.70.80.8-0.80.80.70.50.5-0.50.70.7-0.50.7-0.70.50.7
Weight adjusted by age0.51.41.5-1.21.21.11.21.11.1-1.11.11.21.21.2-1.21.21.2-1.21.2-1.21.21.2
Bone surface1.63.13.6-1.71.71.81.91.81.8-1.81.81.81.71.7-1.71.81.8-1.61.8-1.81.71.8
Bone volume0.30.60.7-0.80.80.80.90.80.8-0.80.80.80.70.7-0.70.80.8-0.80.8-0.80.70.8
Breakpoint value in progressive ratio session0.51.02.11.4-1.4-1.2-0.6-0.3-0.30.3-0.3-0.9-1.2-1.21.2-0.9-0.91.3-0.90.9-1.1-0.8
Number of licking bursts0.00.10.10.1-0.2-0.00.20.40.4-0.40.40.2-0.2-0.20.20.20.20.10.2-0.2-0.10.2
Context. condit. distance diff. score2.73.34.11.7-1.7-1.9-1.7-1.8-1.81.8-1.8-1.8-1.9-1.91.9-1.8-1.81.6-1.81.8-2.0-1.8
Locomotion velocity, session 10.00.10.1-0.1-0.00.10.20.30.3-0.30.30.20.30.3-0.30.20.2-0.20.2-0.20.20.2
Locomotion distance, session 10.81.01.31.1-1.1-1.1-1.0-0.9-0.90.9-0.9-1.0-0.9-0.90.9-1.0-1.01.1-1.01.0-1.0-1.0
Locomotion velocity, session 20.30.40.6-0.50.50.60.50.60.6-0.60.60.60.70.7-0.70.60.6-0.60.6-0.60.60.6
Locomotion distance, session 20.10.10.2-0.00.00.30.20.40.4-0.40.40.30.40.4-0.40.30.3-0.10.3-0.30.40.3
Locomotion velocity, session 30.00.00.00.0-0.20.10.0-0.0-0.00.0-0.0-0.00.10.1-0.1-0.0-0.00.1-0.00.00.1-0.0
Locomotion distance, session 30.00.00.0-0.10.10.1-0.1-0.0-0.00.0-0.00.00.10.1-0.1-0.0-0.0-0.1-0.00.00.1-0.0
Stereotopy head waving bouts, day 30.60.71.11.0-1.1-0.8-0.7-0.7-0.70.7-0.7-0.8-0.9-0.90.9-0.8-0.81.0-0.80.8-0.8-0.8
Stereotopy head waving duration, day 30.70.91.11.1-1.0-0.9-0.9-0.9-0.90.9-0.9-1.0-0.9-0.90.9-1.0-1.01.0-1.01.0-0.8-0.9
Locomotion velocity, session 70.40.41.00.8-1.0-0.7-0.6-0.5-0.50.5-0.5-0.7-0.6-0.60.6-0.6-0.60.8-0.60.6-0.6-0.6
Locomotion distance, session 70.20.20.30.4-0.4-0.4-0.5-0.5-0.50.5-0.5-0.5-0.4-0.40.4-0.5-0.50.4-0.50.5-0.4-0.5
Stereotopy head waving bouts, day 70.91.01.2-0.90.91.01.01.11.1-1.11.11.01.01.0-1.01.11.0-0.91.1-1.11.01.1
Stereotopy head waving duration, day 70.91.11.4-0.90.81.01.11.21.2-1.21.21.01.01.0-1.01.11.1-0.91.1-1.11.01.1
Locomotion velocity, session 80.40.50.60.7-0.7-0.7-0.7-0.7-0.70.7-0.7-0.7-0.6-0.60.6-0.7-0.70.7-0.70.7-0.7-0.7
Locomotion distance, session 81.01.41.81.2-1.2-1.3-1.2-1.1-1.11.1-1.1-1.2-1.3-1.31.3-1.2-1.21.1-1.21.2-1.3-1.2
Degree of sensitization distance0.10.10.2-0.30.30.30.50.30.3-0.30.30.40.30.3-0.30.40.4-0.30.4-0.40.40.4
Degree of sensitization stereotypy1.31.41.6-1.21.21.31.11.21.2-1.21.21.21.21.2-1.21.21.2-1.21.2-1.21.21.2
Conditioned locomotion0.00.00.00.2-0.2-0.0-0.2-0.1-0.10.1-0.1-0.2-0.0-0.00.0-0.2-0.20.1-0.10.10.0-0.1
Cocaine response after cond. corrected0.50.81.2-0.70.60.90.91.11.1-1.11.10.90.80.8-0.80.90.9-0.60.9-0.90.80.9
Cocaine response after cond. not corrected0.40.60.8-0.60.50.70.80.90.9-0.90.90.80.60.6-0.60.80.8-0.50.8-0.80.60.8
Cocaine response before conditioning0.00.00.00.0-0.1-0.1-0.1-0.2-0.20.2-0.2-0.1-0.1-0.10.1-0.1-0.10.0-0.10.1-0.1-0.1
Saline control response0.00.00.2-0.20.3-0.0-0.2-0.2-0.20.2-0.2-0.00.20.2-0.2-0.1-0.1-0.4-0.10.1-0.1-0.1
Bone: connectivity density1.32.02.3-1.41.51.51.41.31.3-1.31.31.41.41.4-1.41.41.4-1.41.4-1.41.41.4
Bone: cortical apparent density4.97.88.12.8-2.8-2.8-2.7-2.7-2.72.7-2.7-2.8-2.8-2.82.8-2.8-2.82.8-2.82.8-2.8-2.8
Bone: cortical area0.20.40.7-0.60.80.60.60.60.6-0.60.60.60.50.5-0.50.60.6-0.60.6-0.60.50.6
Bone: cortical porosity0.30.40.4-0.60.70.60.50.60.6-0.60.60.60.50.5-0.50.60.6-0.60.6-0.60.50.6
Bone: cortical porosity0.60.60.9-0.81.00.70.70.80.8-0.80.80.80.80.8-0.80.80.8-0.90.8-0.80.70.8
Bone: cortical thickness0.20.30.40.5-0.3-0.5-0.6-0.5-0.50.5-0.5-0.5-0.6-0.60.6-0.5-0.50.4-0.50.5-0.7-0.5
Bone: cortical thickness0.00.00.00.00.1-0.1-0.1-0.2-0.20.2-0.2-0.1-0.0-0.00.0-0.1-0.1-0.0-0.10.1-0.1-0.1
Bone: cortical tissue density4.87.67.82.8-2.8-2.8-2.7-2.7-2.72.7-2.7-2.8-2.8-2.82.8-2.8-2.82.7-2.82.8-2.8-2.8
Condit. Reinf. active minus inactive responses0.00.00.00.1-0.10.10.00.10.1-0.10.10.00.10.1-0.10.00.10.10.1-0.10.00.1
Condit. Reinf. active-inactive response ratio0.10.10.10.2-0.3-0.2-0.3-0.3-0.30.3-0.3-0.3-0.2-0.20.2-0.3-0.30.2-0.30.3-0.1-0.3
Condit. Reinf. active responses0.20.30.4-0.30.40.40.40.60.6-0.60.60.50.60.6-0.60.50.5-0.40.5-0.50.40.5
Condit. Reinf. inactive responses0.30.40.7-0.50.70.50.40.60.6-0.60.60.60.80.8-0.80.60.6-0.60.6-0.60.60.6
Incentive salience index mean0.00.00.0-0.0-0.00.10.10.20.2-0.20.20.10.20.2-0.20.10.1-0.00.1-0.10.10.1
Condit. Reinf. lever presses0.10.10.20.4-0.3-0.3-0.4-0.3-0.30.3-0.3-0.3-0.3-0.30.3-0.3-0.30.3-0.30.3-0.4-0.3
Condit. Reinf. active minus inactive responses0.81.21.50.9-0.8-1.0-1.2-1.2-1.21.2-1.2-1.1-1.0-1.01.0-1.1-1.10.7-1.21.2-1.0-1.2
Condit. Reinf. active-inactive response ratio0.20.30.50.3-0.2-0.4-0.7-0.7-0.70.7-0.7-0.5-0.4-0.40.4-0.6-0.60.1-0.60.6-0.4-0.6
Condit. Reinf. active responses0.81.21.50.9-1.1-1.1-1.2-1.2-1.21.2-1.2-1.1-0.9-0.90.9-1.1-1.10.8-1.11.1-1.0-1.1
Condit. Reinf. inactive responses1.62.33.11.6-1.8-1.6-1.5-1.6-1.61.6-1.6-1.6-1.3-1.31.3-1.6-1.51.6-1.51.5-1.4-1.5
Condit. Reinf. lever presses1.92.73.4-1.71.51.71.51.61.6-1.61.61.61.81.8-1.81.61.6-1.81.6-1.61.81.6
Condit. Reinf. lever reinforcers received0.30.50.70.5-0.7-0.7-0.8-0.8-0.80.8-0.8-0.7-0.5-0.50.5-0.7-0.70.4-0.70.7-0.5-0.7
Conditioned reinforcement - actives0.00.10.20.3-0.4-0.2-0.2-0.3-0.30.3-0.3-0.3-0.3-0.30.3-0.2-0.20.4-0.20.2-0.2-0.2
Conditioned reinforcement - inactives0.41.01.61.3-1.1-1.1-0.7-1.1-1.11.1-1.1-0.8-1.1-1.11.1-0.8-0.81.1-0.80.9-1.2-0.8
Conditioned locomotion0.30.40.50.7-0.7-0.6-0.7-0.7-0.70.7-0.7-0.6-0.6-0.60.6-0.6-0.60.7-0.60.6-0.5-0.6
Patch foraging indifference point 0 sec3.610.010.8-3.23.33.13.13.13.1-3.13.13.23.23.2-3.23.23.2-3.23.2-3.23.03.2
Patch foraging indifference point AUC0.51.21.8-0.91.01.01.01.41.4-1.41.41.11.01.0-1.01.11.1-1.01.1-1.11.01.1
Delay disc. indifference point, 0s delay2.02.32.61.4-1.4-1.5-1.6-1.6-1.61.6-1.6-1.5-1.5-1.51.5-1.5-1.51.4-1.51.5-1.5-1.5
Delay disc. indifference point, 16s delay0.20.30.7-0.30.20.40.70.80.8-0.80.80.60.30.3-0.30.60.6-0.30.6-0.60.40.6
Delay disc. indifference point, 2s delay0.40.50.80.7-0.9-0.8-0.6-0.4-0.40.4-0.4-0.6-0.9-0.90.9-0.6-0.60.9-0.60.6-0.9-0.6
Delay disc. indifference point, 24s delay0.20.30.40.6-0.6-0.5-0.5-0.4-0.40.4-0.4-0.5-0.5-0.50.5-0.5-0.50.6-0.50.5-0.5-0.5
Delay disc. indifference point, 4s delay3.84.14.82.1-2.0-2.2-2.1-1.8-1.81.8-1.8-2.0-2.1-2.12.1-2.0-2.02.0-2.02.0-2.2-2.0
Delay disc. indifference point, 8s delay1.52.63.11.7-1.6-1.6-1.6-1.5-1.51.5-1.5-1.6-1.8-1.81.8-1.6-1.61.6-1.51.5-1.7-1.5
Indifference point function ln k0.00.10.30.2-0.3-0.3-0.4-0.5-0.50.5-0.5-0.3-0.3-0.30.3-0.3-0.30.4-0.30.3-0.3-0.4
Indifference point function log k0.00.10.30.2-0.3-0.3-0.4-0.5-0.50.5-0.5-0.3-0.3-0.30.3-0.3-0.30.4-0.30.3-0.3-0.4
Patch foraging total patch changes 0 sec3.19.110.1-3.13.23.03.03.03.0-3.03.03.13.03.0-3.03.13.1-3.13.1-3.12.83.1
Patch foraging total patch changes 12 sec0.60.81.0-0.90.90.80.81.01.0-1.01.00.90.80.8-0.80.90.9-0.90.9-0.90.70.9
Patch foraging total patch changes 18 sec1.12.53.0-1.51.71.61.41.61.6-1.61.61.61.61.6-1.61.61.6-1.61.5-1.51.51.6
Patch foraging total patch changes 24 sec0.51.82.3-1.21.21.21.41.51.5-1.51.51.41.31.3-1.31.41.4-1.21.4-1.41.21.4
Patch foraging total patch changes 6 sec1.83.13.3-1.71.81.71.61.81.8-1.81.81.81.71.7-1.71.81.8-1.81.8-1.81.61.8
Patch foraging time to switch 0 sec0.82.93.51.7-1.7-1.9-1.5-1.7-1.71.7-1.7-1.7-1.9-1.91.9-1.6-1.61.7-1.61.6-1.8-1.6
Patch foraging water rate 0 sec0.72.52.9-1.51.51.61.61.71.7-1.71.71.61.51.5-1.51.61.6-1.41.6-1.61.51.6
Patch foraging water rate 12 sec1.24.85.1-2.22.32.22.12.22.2-2.22.22.22.12.1-2.12.22.2-2.22.2-2.22.12.2
Patch foraging water rate 18 sec0.10.20.3-0.30.40.30.50.50.5-0.50.50.40.20.2-0.20.40.4-0.30.4-0.40.20.4
Patch foraging water rate 24 sec0.00.10.20.3-0.2-0.20.00.20.2-0.20.2-0.0-0.4-0.40.4-0.0-0.00.3-0.00.0-0.40.0
Patch foraging water rate 6 sec0.20.30.4-0.50.50.60.60.50.5-0.50.50.50.50.5-0.50.50.5-0.30.5-0.50.60.5
Seeking ratio, delayed vs. immediate footshock0.00.10.20.4-0.5-0.3-0.30.20.2-0.20.2-0.2-0.2-0.20.2-0.2-0.20.3-0.20.2-0.3-0.2
Distance traveled before self-admin0.10.20.60.3-0.1-0.20.50.80.8-0.80.80.2-0.2-0.20.20.20.2-0.00.2-0.2-0.40.3
Distance traveled after self-admin0.10.30.90.4-0.2-0.20.50.90.9-0.90.90.3-0.2-0.20.20.30.30.10.3-0.3-0.20.4
Extensor digitorum longus weight0.62.32.81.5-1.7-1.4-1.5-1.6-1.61.6-1.6-1.6-1.4-1.41.4-1.6-1.61.5-1.61.6-1.3-1.6
Bone: elastic displacement0.50.70.80.7-0.6-0.8-0.9-0.9-0.90.9-0.9-0.8-0.7-0.70.7-0.9-0.90.6-0.90.9-0.8-0.9
Bone: elastic work1.62.12.31.3-1.2-1.4-1.5-1.5-1.51.5-1.5-1.5-1.4-1.41.4-1.5-1.51.3-1.51.5-1.5-1.5
Bone: endosteal estimation0.71.82.1-1.31.41.31.51.31.3-1.31.31.41.31.3-1.31.41.4-1.21.4-1.41.31.4
Bone: endosteal perimeter1.22.93.4-1.61.71.61.91.81.8-1.81.81.81.61.6-1.61.81.8-1.51.8-1.81.61.8
Epididymis fat weight0.00.20.60.7-0.6-0.5-0.6-0.3-0.30.3-0.3-0.5-0.4-0.40.4-0.5-0.50.7-0.50.5-0.5-0.5
Delta time in closed arm before/after self-admin0.10.10.4-0.60.40.40.30.10.1-0.10.10.20.40.4-0.40.20.2-0.40.2-0.20.40.2
Delta time in open arm before/after self-admin1.31.51.7-1.31.21.31.21.11.1-1.11.11.31.31.3-1.31.31.3-1.21.3-1.31.21.3
Diff in mean of infusions in LGA sessions0.10.10.3-0.10.20.20.50.40.4-0.40.40.30.20.2-0.20.30.4-0.20.3-0.30.30.4
Delay discount exponential model param1.01.41.9-1.31.31.31.10.90.9-0.90.91.11.41.4-1.41.11.1-1.31.1-1.11.31.1
Extinction: sum of active levers before priming0.40.61.20.9-0.8-0.9-0.4-0.5-0.50.5-0.5-0.7-1.1-1.11.1-0.7-0.70.9-0.70.7-1.0-0.7
Active lever presses in extinction session 60.00.00.1-0.00.1-0.10.3-0.0-0.00.0-0.00.1-0.1-0.10.10.10.1-0.20.1-0.1-0.10.1
Bone: final force0.20.40.50.6-0.5-0.6-0.5-0.5-0.50.5-0.5-0.6-0.7-0.70.7-0.6-0.60.7-0.60.6-0.7-0.6
Bone: final moment0.00.00.0-0.10.20.00.10.10.1-0.10.10.1-0.0-0.00.00.10.10.00.1-0.1-0.00.0
Food consumed during 24 hour testing period0.30.61.11.0-1.0-0.9-0.6-0.6-0.60.6-0.6-0.7-0.8-0.80.8-0.7-0.71.0-0.70.7-0.9-0.7
Glucose0.30.51.6-1.01.30.80.40.40.4-0.40.40.60.90.9-0.90.60.6-1.20.5-0.50.70.5
Heart weight2.13.43.71.8-1.6-1.9-1.9-1.8-1.81.8-1.8-1.9-1.9-1.91.9-1.9-1.91.7-1.91.9-1.9-1.9
Delay discount hyperbolic model param0.91.21.7-1.21.31.21.10.80.8-0.80.81.01.31.3-1.31.01.0-1.31.0-1.01.31.0
Intermittent access intake day 1-15 change0.10.41.21.0-1.1-0.7-0.3-0.2-0.20.2-0.2-0.5-0.7-0.70.7-0.5-0.50.9-0.40.4-0.6-0.4
Intermittent access intake escalation0.10.61.61.2-1.3-0.9-0.5-0.3-0.30.3-0.3-0.7-0.9-0.90.9-0.7-0.61.0-0.60.6-0.7-0.6
Intermittent access intake escalation 20.30.51.31.2-1.1-0.9-0.4-0.1-0.10.1-0.1-0.6-0.9-0.90.9-0.6-0.61.0-0.60.6-0.7-0.5
Intermitt. access day 1 inactive lever presses0.00.10.4-0.60.60.30.2-0.0-0.00.0-0.00.40.40.4-0.40.40.4-0.60.4-0.40.30.4
Intermitt. access day 15 inactive lever presses0.31.92.71.3-1.2-1.3-1.4-1.6-1.61.6-1.6-1.3-1.2-1.21.2-1.3-1.31.1-1.31.3-1.3-1.3
Intermitt. access escalation Index0.20.81.3-1.10.91.00.80.80.8-0.80.80.71.01.0-1.00.80.7-0.70.8-0.81.10.7
Intermittent access day 1 total infusions0.41.32.20.8-0.8-0.9-1.5-1.5-1.51.5-1.5-1.1-0.8-0.80.8-1.1-1.10.7-1.11.1-0.9-1.1
Intermittent access day 15 total infusions0.41.01.41.0-1.1-0.9-1.2-1.1-1.11.1-1.1-1.0-0.8-0.80.8-1.0-1.00.9-1.01.0-0.8-1.0
Intermittent access terminal intake (last 3 days)0.40.71.01.0-1.0-0.8-0.9-0.8-0.80.8-0.8-0.8-0.8-0.80.8-0.8-0.80.8-0.80.8-0.7-0.7
Intermittent access total infusions1.11.32.10.9-0.9-0.9-1.5-1.4-1.41.4-1.4-1.1-0.8-0.80.8-1.1-1.10.8-1.11.1-0.8-1.2
Intermittent access day 1 locomotion0.10.10.3-0.30.30.2-0.5-0.5-0.50.5-0.5-0.10.30.3-0.3-0.1-0.1-0.4-0.10.10.3-0.1
Intermittent access day 15 total locomotion0.00.00.1-0.0-0.00.1-0.3-0.3-0.30.3-0.3-0.00.10.1-0.1-0.1-0.1-0.1-0.10.10.2-0.1
Intermittent access total locomotion0.00.00.1-0.10.20.2-0.3-0.2-0.20.2-0.20.00.20.2-0.20.00.0-0.30.0-0.00.30.0
Intermittent access standard deviation0.10.80.90.9-0.8-0.8-1.0-0.9-0.90.9-0.9-0.8-0.9-0.90.9-0.8-0.80.9-0.80.8-0.7-0.8
Left kidney weight0.10.81.11.0-1.0-0.9-0.8-0.7-0.70.7-0.7-0.9-1.0-1.01.0-0.9-0.90.9-0.80.8-0.9-0.8
Right kidney weight0.10.81.31.1-1.1-1.0-0.9-0.5-0.50.5-0.5-0.9-1.1-1.11.1-0.9-0.91.0-0.90.9-1.0-0.8
Cocaine induced anxiety0.00.00.2-0.40.40.2-0.1-0.1-0.10.1-0.10.10.20.2-0.20.10.1-0.40.1-0.10.10.0
Post-drug Anxiety0.00.00.1-0.30.20.1-0.2-0.2-0.20.2-0.2-0.00.00.0-0.0-0.0-0.1-0.2-0.00.00.1-0.1
Baseline Anxiety0.00.00.0-0.0-0.10.10.20.10.1-0.10.1-0.00.00.0-0.00.00.00.10.0-0.00.20.0
Tail length0.20.92.01.4-1.2-1.2-0.7-0.3-0.30.3-0.3-0.8-1.4-1.41.4-0.8-0.81.2-0.80.8-1.3-0.7
Length with tail0.20.81.81.3-1.0-1.1-0.6-0.3-0.30.3-0.3-0.8-1.2-1.21.2-0.8-0.71.1-0.80.8-1.1-0.7
Length without tail0.00.10.30.6-0.4-0.5-0.1-0.2-0.20.2-0.2-0.3-0.3-0.30.3-0.3-0.30.4-0.30.3-0.4-0.3
Times rat made contact with spout0.00.00.1-0.10.1-0.10.10.00.0-0.00.00.1-0.1-0.10.10.10.1-0.10.1-0.1-0.20.1
Lifetime Intake1.11.32.20.9-0.9-0.9-1.5-1.5-1.51.5-1.5-1.2-0.8-0.80.8-1.2-1.20.8-1.21.2-0.8-1.2
Liver weight, left2.84.85.52.2-1.9-2.3-2.3-2.2-2.22.2-2.2-2.2-2.2-2.22.2-2.2-2.21.9-2.32.3-2.4-2.2
Liver weight, right2.23.84.32.0-1.8-2.1-2.0-1.9-1.91.9-1.9-2.0-1.9-1.91.9-2.0-2.01.8-2.02.0-2.1-1.9
Locomotor activity0.00.00.0-0.00.20.00.10.10.1-0.10.10.00.10.1-0.10.00.0-0.0-0.00.00.10.0
Locomotor testing distance0.82.02.4-1.31.31.41.51.51.5-1.51.51.41.51.5-1.51.41.4-1.31.4-1.41.41.4
Locomotor testing rearing0.00.10.20.3-0.3-0.3-0.1-0.1-0.10.1-0.1-0.2-0.3-0.30.3-0.2-0.20.2-0.20.2-0.4-0.2
Locomotion in novel chamber1.92.52.9-1.61.31.61.71.51.5-1.51.51.61.61.6-1.61.61.6-1.51.6-1.61.71.6
Locomotion in novel chamber post-restriction0.10.20.30.10.0-0.3-0.2-0.6-0.60.6-0.6-0.4-0.4-0.40.4-0.4-0.40.3-0.40.4-0.3-0.5
Fecal boli incidents, locomotor time 10.00.00.1-0.10.00.1-0.0-0.2-0.20.2-0.20.00.20.2-0.2-0.0-0.0-0.1-0.00.00.0-0.0
Change in fecal boli incidents, locomotor task0.10.10.20.4-0.4-0.3-0.4-0.2-0.20.2-0.2-0.4-0.4-0.40.4-0.3-0.30.4-0.40.4-0.3-0.3
Time >=10cm from walls, locomotor time 10.10.10.3-0.30.30.40.30.20.2-0.20.20.30.50.5-0.50.30.3-0.40.3-0.30.50.3
Bouts of movement, locomotor time 10.10.10.2-0.30.40.40.10.10.1-0.10.10.20.40.4-0.40.20.2-0.30.2-0.20.50.2
Total resting periods, locomotor time 10.10.10.2-0.30.40.40.10.20.2-0.20.20.20.40.4-0.40.20.2-0.40.2-0.20.40.2
Rest time, locomotor task time 10.10.20.4-0.30.50.40.40.60.6-0.60.60.50.30.3-0.30.50.5-0.40.5-0.40.20.5
Distance moved, locomotor task time 10.00.10.2-0.20.0-0.1-0.0-0.4-0.40.4-0.4-0.2-0.2-0.20.2-0.1-0.20.2-0.10.1-0.0-0.2
Vertical activity count, locomotor time 10.00.20.3-0.60.60.50.40.40.4-0.40.40.50.10.1-0.10.50.5-0.30.5-0.50.40.5
Time >=10cm from walls, locomotor time 21.02.93.71.5-1.6-1.6-1.7-1.9-1.91.9-1.9-1.7-1.6-1.61.6-1.7-1.71.6-1.71.6-1.5-1.7
Bouts of movement, locomotor time 20.30.91.5-1.11.21.10.60.60.6-0.60.61.01.01.0-1.01.00.9-1.20.9-0.90.90.9
Total resting periods, locomotor time 20.31.01.8-1.21.21.10.60.70.7-0.70.71.01.11.1-1.11.01.0-1.31.0-1.01.11.0
Rest time, locomotor task time 20.50.81.2-0.70.70.80.81.11.1-1.11.10.80.90.9-0.90.80.8-0.90.8-0.80.80.9
Distance moved, locomotor task time 21.01.31.70.8-1.0-1.0-0.9-1.3-1.31.3-1.3-1.1-1.3-1.31.3-1.0-1.11.2-1.01.0-1.1-1.1
Vertical activity count, locomotor time 20.20.40.80.4-0.3-0.4-0.5-0.7-0.70.7-0.7-0.5-0.9-0.90.9-0.5-0.50.6-0.50.5-0.6-0.5
Light reinforcement 10.10.70.70.8-0.7-0.8-0.8-0.8-0.80.8-0.8-0.8-0.8-0.80.8-0.8-0.80.8-0.80.8-0.8-0.8
Light reinforcement 20.10.20.30.4-0.3-0.4-0.3-0.3-0.30.3-0.3-0.4-0.6-0.60.6-0.4-0.40.5-0.40.4-0.5-0.4
Bone: marrow area0.61.51.9-1.21.31.21.41.21.2-1.21.21.31.21.2-1.21.31.3-1.11.3-1.31.21.3
Bone: maximum diameter0.40.81.1-0.91.00.91.00.90.9-0.90.90.90.80.8-0.80.90.9-0.80.9-0.90.80.9
Bone: maximum force0.00.00.10.10.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.2-0.20.2-0.1-0.10.2-0.10.1-0.3-0.1
Bone: maximum moment0.20.30.6-0.60.80.60.60.60.6-0.60.60.60.50.5-0.50.60.6-0.60.6-0.60.50.6
Mean time between licks in bursts1.48.59.22.9-2.9-3.0-2.8-2.9-2.92.9-2.9-2.9-3.0-3.03.0-2.9-2.92.9-2.92.9-3.0-2.9
Mean num. licks in bursts0.00.10.2-0.30.40.1-0.1-0.2-0.20.2-0.20.00.30.3-0.30.00.0-0.4-0.00.00.1-0.0
Cd content in liver1.21.41.9-1.31.41.21.01.01.0-1.01.01.11.31.3-1.31.11.1-1.41.1-1.11.21.1
Co content in liver0.00.00.10.2-0.1-0.2-0.1-0.2-0.20.2-0.2-0.2-0.2-0.20.2-0.2-0.20.3-0.20.2-0.3-0.2
Cu content in liver0.91.01.21.0-1.0-1.1-1.0-1.0-1.01.0-1.0-1.0-1.0-1.01.0-1.0-1.01.0-1.01.0-1.1-1.0
Fe content in liver0.00.00.0-0.1-0.00.1-0.2-0.2-0.20.2-0.2-0.10.10.1-0.1-0.1-0.1-0.0-0.10.10.1-0.2
K content in liver1.91.82.31.4-1.3-1.5-1.3-1.3-1.31.3-1.3-1.3-1.4-1.41.4-1.3-1.31.5-1.31.3-1.5-1.3
Mg content in liver0.40.40.6-0.50.50.50.80.80.8-0.80.80.70.50.5-0.50.70.7-0.50.7-0.70.40.7
Mn content in liver0.10.10.1-0.20.20.10.30.30.3-0.30.30.30.20.2-0.20.30.3-0.10.3-0.30.10.3
Na content in liver3.33.74.21.9-2.1-1.9-1.9-1.9-1.91.9-1.9-2.0-1.8-1.81.8-2.0-2.02.0-1.91.9-1.8-2.0
Rb content in liver0.50.61.00.9-1.0-0.9-0.6-0.7-0.70.7-0.7-0.7-0.8-0.80.8-0.7-0.70.9-0.70.7-0.8-0.7
Se content in liver0.20.20.4-0.50.60.50.30.40.4-0.40.40.40.50.5-0.50.40.4-0.30.4-0.40.40.4
Sr content in liver1.31.11.2-1.11.01.11.01.01.0-1.01.01.01.11.1-1.11.01.0-0.91.0-1.11.11.0
Zn content in liver1.01.22.1-1.21.41.11.11.01.0-1.01.01.11.01.0-1.01.11.1-1.21.1-1.11.01.1
Bone: minimum diameter1.52.93.6-1.71.91.61.71.81.8-1.81.81.71.61.6-1.61.71.7-1.61.7-1.71.51.8
Time in familiar zone, hab. session 12.62.93.11.8-1.7-1.7-1.8-1.7-1.71.7-1.7-1.7-1.7-1.71.7-1.7-1.71.7-1.71.7-1.7-1.7
Time in novel zone, hab. session 16.77.58.0-2.82.62.82.82.72.7-2.72.72.82.82.8-2.82.82.8-2.72.8-2.82.82.7
Total zone transitions, hab. session 11.92.63.21.7-1.7-1.7-1.5-1.5-1.51.5-1.5-1.6-1.7-1.71.7-1.6-1.61.8-1.61.6-1.7-1.6
Total locomotion distance, hab. session 10.10.20.40.6-0.6-0.4-0.3-0.3-0.30.3-0.3-0.4-0.5-0.50.5-0.4-0.40.7-0.30.3-0.4-0.3
Locomotion velocity, hab. session 10.20.20.60.7-0.7-0.5-0.3-0.3-0.30.3-0.3-0.5-0.5-0.50.5-0.4-0.40.7-0.40.4-0.5-0.4
Time in familiar zone, hab. session 20.50.60.60.8-0.7-0.7-0.8-0.7-0.70.7-0.7-0.8-0.7-0.70.7-0.8-0.80.8-0.80.8-0.7-0.8
Time in novel zone, hab. session 21.01.11.2-1.11.01.01.11.11.1-1.11.11.11.11.1-1.11.11.1-1.11.1-1.11.11.1
Total zone transitions, hab. session 24.86.28.22.7-2.9-2.5-2.4-2.3-2.32.3-2.3-2.5-2.4-2.42.4-2.5-2.52.8-2.52.5-2.4-2.4
Total locomotion distance, hab. session 22.12.74.31.9-2.1-1.7-1.5-1.5-1.51.5-1.5-1.7-1.6-1.61.6-1.6-1.62.0-1.61.6-1.5-1.6
Locomotion velocity, hab. session 21.82.43.81.8-2.0-1.6-1.4-1.4-1.41.4-1.4-1.6-1.5-1.51.5-1.5-1.51.9-1.51.5-1.4-1.5
Novel to familiar place preference ratio0.91.21.5-1.21.21.01.21.01.0-1.01.01.11.11.1-1.11.11.1-1.21.1-1.11.01.1
Novelty place preference0.70.91.1-1.01.00.91.10.90.9-0.90.91.00.90.9-0.90.90.9-1.00.9-0.90.80.9
Time in novel zone, NPP test1.11.31.6-1.31.21.11.31.11.1-1.11.11.21.21.2-1.21.21.2-1.31.2-1.21.11.1
Total zone transitions, NPP test1.82.63.21.8-1.7-1.6-1.6-1.5-1.51.5-1.5-1.6-1.6-1.61.6-1.6-1.61.7-1.61.6-1.6-1.6
Total locomotion distance, NPP test0.20.20.50.7-0.7-0.6-0.4-0.3-0.30.3-0.3-0.5-0.5-0.50.5-0.5-0.50.7-0.40.4-0.5-0.4
Locomotion velocity, NPP test0.40.61.01.0-1.0-0.8-0.7-0.6-0.60.6-0.6-0.7-0.7-0.70.7-0.7-0.71.0-0.70.7-0.8-0.7
Intraocular pressure0.00.00.1-0.30.40.2-0.3-0.2-0.20.2-0.2-0.1-0.1-0.10.1-0.1-0.1-0.2-0.10.10.1-0.1
Delta distance traveled before/after self-admin0.20.20.4-0.10.40.30.40.60.6-0.60.60.40.30.3-0.30.40.4-0.30.4-0.40.40.4
Delta ambulatory time before/after self-admin0.00.00.10.20.10.00.00.30.3-0.30.30.1-0.0-0.00.00.10.10.10.1-0.10.10.2
Parametrial fat weight7.216.917.3-4.24.14.04.14.14.1-4.14.14.14.14.1-4.14.14.1-4.14.1-4.14.04.1
Pavlov. Cond. lever latency0.30.30.50.6-0.5-0.7-0.7-0.5-0.50.5-0.5-0.6-0.6-0.60.6-0.6-0.60.5-0.60.6-0.6-0.5
Pavlov. Cond. magazine entry latency0.40.50.60.6-0.7-0.5-0.7-0.8-0.80.8-0.8-0.7-0.6-0.60.6-0.7-0.70.6-0.70.7-0.5-0.7
Pavlov. Cond. change in total contacts0.50.50.8-0.80.80.90.70.60.6-0.60.60.70.80.8-0.80.70.7-0.80.7-0.70.80.7
Pavlov. Cond. index score0.00.00.1-0.20.00.30.1-0.1-0.10.1-0.10.00.10.1-0.10.00.0-0.10.0-0.00.3-0.0
Pavlov. Cond. latency score0.00.00.1-0.30.10.40.20.00.0-0.00.00.10.30.3-0.30.10.1-0.20.1-0.10.40.1
Pavlov. Cond. lever contacts0.00.00.1-0.30.20.30.30.10.1-0.10.10.20.20.2-0.20.20.2-0.20.2-0.20.30.2
Pavlov. Cond. magazine entry number0.70.91.2-0.80.90.71.01.11.1-1.11.11.00.80.8-0.81.01.0-0.81.0-1.00.61.0
Pavlov. Cond. intertrial magazine entries0.60.81.10.9-0.9-1.0-0.9-0.8-0.80.8-0.8-0.9-0.8-0.80.8-0.9-0.90.9-0.90.9-1.0-0.9
Pavlov. Cond. lever-magazine prob. diff.0.00.10.2-0.30.20.40.20.00.0-0.00.00.20.30.3-0.30.10.1-0.20.2-0.20.40.1
Pavlov. Cond. response bias0.10.20.20.3-0.4-0.2-0.3-0.5-0.50.5-0.5-0.4-0.3-0.30.3-0.4-0.40.4-0.40.4-0.2-0.4
Pavlov. Cond. lever latency1.72.53.21.7-1.6-1.6-1.4-1.4-1.41.4-1.4-1.5-1.8-1.81.8-1.5-1.51.8-1.51.5-1.8-1.5
Pavlov. Cond. magazine entry latency1.31.92.5-1.51.51.61.31.21.2-1.21.21.31.51.5-1.51.31.3-1.51.3-1.31.51.3
Pavlov. Cond. change in total contacts1.12.63.4-1.61.51.71.61.51.5-1.51.51.61.81.8-1.81.61.6-1.61.6-1.61.81.5
Pavlov. Cond. index score1.21.92.5-1.51.41.51.31.21.2-1.21.21.31.61.6-1.61.31.3-1.51.3-1.31.61.3
Pavlov. Cond. latency score1.01.72.2-1.41.31.41.21.11.1-1.11.11.21.51.5-1.51.21.2-1.41.2-1.21.51.2
Pavlov. Cond. lever contacts1.82.63.3-1.71.61.71.51.41.4-1.41.41.61.81.8-1.81.61.6-1.81.5-1.51.81.5
Pavlov. Cond. magazine entry number0.40.61.00.9-0.9-1.0-0.6-0.5-0.50.5-0.5-0.7-0.9-0.90.9-0.7-0.71.0-0.70.7-1.0-0.6
Pavlov. Cond. intertrial magazine entries0.71.51.81.2-1.3-1.2-1.2-1.2-1.21.2-1.2-1.2-1.1-1.11.1-1.2-1.21.2-1.21.2-1.2-1.2
Pavlov. Cond. lever-magazine prob. diff.1.32.02.6-1.51.51.61.31.21.2-1.21.21.41.61.6-1.61.41.4-1.61.4-1.41.61.3
Pavlov. Cond. response bias1.52.12.8-1.51.51.51.31.31.3-1.31.31.41.71.7-1.71.41.4-1.61.4-1.41.71.3
Time in closed arm before self-admin0.10.20.50.5-0.6-0.3-0.7-0.4-0.40.4-0.4-0.5-0.5-0.50.5-0.5-0.50.6-0.50.5-0.4-0.5
Time in closed arm after self-admin0.00.00.1-0.2-0.10.1-0.4-0.1-0.10.1-0.1-0.2-0.0-0.00.0-0.2-0.20.2-0.20.20.2-0.3
Time in open arm before self-admin0.10.20.40.4-0.0-0.20.60.70.7-0.70.70.30.00.0-0.00.30.30.00.3-0.3-0.20.4
Time in open arm after self-admin2.42.73.2-1.41.51.51.81.61.6-1.61.61.71.61.6-1.61.71.7-1.61.7-1.71.41.8
Bone: periosteal estimation0.61.51.8-1.21.41.21.31.31.3-1.31.31.31.11.1-1.11.31.3-1.11.3-1.21.11.3
Bone: periosteal perimeter0.40.81.2-0.91.10.81.01.01.0-1.01.00.90.80.8-0.80.90.9-0.90.9-0.90.70.9
Bone: post-yield work1.32.22.4-1.41.51.41.51.51.5-1.51.51.51.41.4-1.41.51.5-1.31.5-1.51.51.5
Progressive ratio test 1 active lever presses1.73.04.91.3-1.2-1.5-2.2-2.2-2.22.2-2.2-1.8-1.3-1.31.3-1.8-1.81.1-1.81.8-1.4-1.9
Progressive ratio test 1 breakpoint2.13.65.71.5-1.4-1.7-2.3-2.4-2.42.4-2.4-1.9-1.4-1.41.4-2.0-2.01.3-2.02.0-1.6-2.0
Progressive ratio test 1 inactive lever presses1.84.77.21.7-1.6-2.0-2.7-2.7-2.72.7-2.7-2.1-1.8-1.81.8-2.2-2.21.4-2.22.2-1.9-2.2
Progressive ratio test 2 active lever presses0.10.10.20.2-0.1-0.3-0.5-0.5-0.50.5-0.5-0.3-0.2-0.20.2-0.3-0.30.1-0.30.3-0.2-0.3
Progressive ratio test 2 breakpoint0.20.20.40.4-0.3-0.4-0.6-0.6-0.60.6-0.6-0.4-0.3-0.30.3-0.5-0.50.2-0.50.5-0.4-0.5
Progressive ratio test 2 inactive lever presses0.20.71.00.9-0.7-0.8-0.8-1.0-1.01.0-1.0-0.7-0.8-0.80.8-0.7-0.70.7-0.70.8-0.9-0.7
Incentive Sensitization - Responses0.10.30.4-0.60.60.50.60.50.5-0.50.50.60.50.5-0.50.60.6-0.60.6-0.60.50.6
Incentive Sensitization - Breakpoint0.20.50.7-0.70.70.60.80.70.7-0.70.70.70.60.6-0.60.70.7-0.70.7-0.70.60.8
Sum of active levers in priming session hrs 5-60.70.71.41.2-1.1-0.9-0.4-0.5-0.50.5-0.5-0.7-1.1-1.11.1-0.7-0.71.1-0.70.7-0.9-0.6
Progressive ratio0.10.40.90.9-0.9-0.8-0.4-0.3-0.30.3-0.3-0.6-0.8-0.80.8-0.6-0.60.9-0.60.6-0.7-0.5
Food seeking constrained by brief footshock4.15.15.62.3-2.3-2.3-2.1-2.4-2.42.4-2.4-2.3-2.1-2.12.1-2.3-2.32.2-2.32.3-2.2-2.3
Seeking ratio, punishment vs. effort0.41.01.40.8-0.8-0.9-1.1-1.2-1.21.2-1.2-1.1-0.7-0.70.7-1.0-1.10.7-1.01.0-0.9-1.1
Retroperitoneal fat weight0.41.72.8-0.90.91.11.31.71.7-1.71.71.31.21.2-1.21.31.3-0.91.3-1.31.11.4
Reaction time number correct0.00.00.10.2-0.0-0.10.10.30.3-0.30.30.1-0.1-0.10.10.10.1-0.10.1-0.0-0.10.1
Reaction time mean minus median0.00.30.6-0.20.10.50.80.80.8-0.80.80.50.30.3-0.30.60.6-0.20.6-0.60.50.6
Reaction time mean minus median AUC0.00.00.10.1-0.30.10.30.20.2-0.20.20.1-0.1-0.10.10.10.10.20.1-0.10.00.1
Reaction time num false alarms0.10.20.4-0.50.40.60.50.40.4-0.40.40.50.60.6-0.60.50.5-0.50.5-0.50.60.5
Reaction time num false alarms AUC0.40.91.2-1.00.91.11.00.80.8-0.80.80.91.11.1-1.10.90.9-1.00.9-0.91.10.9
Reaction time trials correct on left0.00.00.10.2-0.0-0.10.10.30.3-0.30.30.1-0.1-0.10.10.10.1-0.10.1-0.0-0.10.1
Reaction time trials on left0.00.00.10.10.1-0.00.10.30.3-0.30.30.10.00.0-0.00.10.1-0.20.1-0.1-0.00.2
Reaction time mean0.51.21.5-1.10.91.21.21.11.1-1.11.11.11.11.1-1.11.11.1-1.01.1-1.11.21.1
Reaction time mean AUC0.20.50.7-0.70.50.80.80.70.7-0.70.70.70.70.7-0.70.70.7-0.60.7-0.70.80.7
Median of all reaction times1.01.52.0-1.31.11.41.31.11.1-1.11.11.21.31.3-1.31.21.2-1.21.2-1.21.41.2
Reaction time omissions1.01.62.4-1.51.51.41.11.11.1-1.11.11.21.41.4-1.41.21.2-1.61.1-1.11.31.1
Reaction time false alarm rate0.81.11.5-1.21.11.21.00.80.8-0.80.81.01.21.2-1.21.01.0-1.01.0-1.01.21.0
Reaction time premature initiation rate0.40.61.00.7-0.6-0.7-1.0-0.7-0.70.7-0.7-0.8-0.9-0.90.9-0.8-0.80.8-0.80.8-0.7-0.8
Reaction time premature initiations0.30.91.31.1-0.8-0.9-1.1-0.8-0.80.8-0.8-1.0-1.1-1.11.1-1.0-1.00.9-1.01.0-0.9-0.9
Std. dev. reaction times0.72.23.2-1.31.21.51.81.61.6-1.61.61.51.31.3-1.31.51.5-1.21.6-1.61.51.6
Reaction time trials completed0.00.00.10.10.1-0.00.10.30.3-0.30.30.10.00.0-0.00.10.1-0.20.1-0.1-0.00.2
Reaction time trials AUC0.00.00.10.10.1-0.00.10.30.3-0.30.30.10.00.0-0.00.10.1-0.20.1-0.1-0.00.2
Run reversals in cocaine runway, females0.00.10.10.20.0-0.2-0.2-0.2-0.20.2-0.2-0.3-0.2-0.20.2-0.3-0.30.3-0.30.3-0.2-0.3
Run reversals in cocaine runway, males0.50.50.9-0.70.70.70.60.90.9-0.90.90.70.70.7-0.70.70.7-0.50.7-0.70.70.7
Latency to leave start box in cocaine runway0.20.20.30.5-0.3-0.5-0.5-0.4-0.40.4-0.4-0.5-0.6-0.60.6-0.5-0.50.5-0.50.5-0.6-0.5
Latency to leave start box in cocaine runway, F0.10.20.4-0.40.60.40.50.40.4-0.40.40.40.40.4-0.40.40.4-0.40.4-0.40.30.4
Latency to leave start box in cocaine runway, M0.90.81.00.9-0.8-0.9-1.0-0.9-0.90.9-0.9-0.9-0.9-0.90.9-0.9-0.90.9-0.90.9-0.9-0.9
Std. dev. time between licks in bursts0.00.00.10.0-0.0-0.20.10.10.1-0.10.10.0-0.3-0.30.30.00.00.10.1-0.1-0.30.1
Total sessions with >9 infusions2.02.53.61.5-1.5-1.6-1.8-1.9-1.91.9-1.9-1.6-1.2-1.21.2-1.6-1.61.3-1.61.6-1.3-1.6
Short access day 1 total inactive lever presses0.00.10.30.1-0.0-0.3-0.2-0.5-0.50.5-0.5-0.2-0.1-0.10.1-0.2-0.2-0.0-0.20.2-0.4-0.2
Short access day 10 total inactive lever presses0.21.72.3-1.51.51.41.21.01.0-1.01.01.41.31.3-1.31.41.4-1.31.4-1.41.31.4
Short access day 1 total infusions0.10.20.60.3-0.5-0.4-0.6-0.7-0.70.7-0.7-0.5-0.2-0.20.2-0.5-0.50.2-0.50.5-0.2-0.5
Short access day 10 total infusions1.01.72.61.2-1.0-1.2-1.6-1.6-1.61.6-1.6-1.3-1.0-1.01.0-1.3-1.31.0-1.31.3-1.1-1.3
Short access total infusions0.60.91.70.6-0.7-0.7-1.2-1.3-1.31.3-1.3-0.9-0.5-0.50.5-1.0-0.90.6-1.01.0-0.6-1.0
Short access day 1 locomotion0.10.10.2-0.30.10.1-0.5-0.5-0.50.5-0.5-0.10.40.4-0.4-0.1-0.1-0.3-0.10.10.3-0.2
Short access day 10 total locomotion0.10.60.9-0.91.00.80.50.50.5-0.50.50.71.01.0-1.00.70.7-1.00.7-0.70.90.7
Short access total locomotion0.20.30.80.2-0.3-0.3-0.8-0.9-0.90.9-0.9-0.5-0.1-0.10.1-0.5-0.50.2-0.50.5-0.1-0.6
One hour access (0.3 mA shock)0.10.10.30.3-0.3-0.2-0.5-0.5-0.50.5-0.5-0.3-0.2-0.20.2-0.3-0.30.3-0.30.3-0.2-0.3
Compulsive drug intake3.14.56.8-2.62.62.31.91.81.8-1.81.82.12.22.2-2.22.12.1-2.52.0-2.12.22.0
One hour access (shock baseline)1.23.13.81.9-1.9-1.8-1.8-1.8-1.81.8-1.8-1.7-1.7-1.71.7-1.7-1.71.9-1.71.7-1.7-1.7
Social response proportion1.21.52.0-1.41.31.21.11.11.1-1.11.11.21.31.3-1.31.21.2-1.41.2-1.21.21.2
Social responses0.40.50.80.4-0.3-0.7-0.9-0.8-0.80.8-0.8-0.7-0.6-0.60.6-0.7-0.70.3-0.70.8-0.8-0.8
Social time0.10.10.5-0.60.60.30.1-0.0-0.00.0-0.00.20.40.4-0.40.20.2-0.70.1-0.10.30.1
Soleus weight0.00.10.40.5-0.6-0.3-0.2-0.3-0.30.3-0.3-0.3-0.3-0.30.3-0.3-0.30.6-0.30.3-0.2-0.3
Bone: stiffness0.00.00.10.2-0.1-0.2-0.0-0.0-0.00.0-0.0-0.1-0.2-0.20.2-0.1-0.10.2-0.10.1-0.3-0.1
Tibialis anterior weight8.128.129.4-5.45.25.45.35.25.2-5.25.25.35.35.3-5.35.35.3-5.35.3-5.35.45.3
Time to tail flick, vehicle, before self-admin1.11.32.1-0.81.00.91.51.41.4-1.41.41.20.90.9-0.91.21.2-1.11.2-1.20.91.2
Time to tail flick, vehicle, after self-admin0.81.52.4-1.01.11.11.21.51.5-1.51.51.21.11.1-1.11.21.2-1.01.2-1.21.11.3
Time to tail flick, test, before self-admin0.00.00.00.10.1-0.2-0.1-0.1-0.10.1-0.1-0.0-0.2-0.20.2-0.0-0.0-0.1-0.00.1-0.1-0.0
Time to tail flick, test, after self-admin0.30.30.40.6-0.5-0.6-0.4-0.5-0.50.5-0.5-0.5-0.6-0.60.6-0.5-0.50.5-0.50.5-0.6-0.5
Delta time to tail flick, vehicle, before/after SA0.10.10.20.1-0.2-0.1-0.5-0.3-0.30.3-0.3-0.3-0.1-0.10.1-0.2-0.30.4-0.20.2-0.1-0.3
Delta time to tail flick, test, before/after SA0.10.10.1-0.30.30.40.30.30.3-0.30.30.30.30.3-0.30.30.3-0.20.4-0.40.30.3
Tibia length2.87.98.72.9-2.9-2.8-2.8-2.7-2.72.7-2.7-2.8-2.8-2.82.8-2.8-2.82.8-2.82.8-2.8-2.8
Ambulatory time before self-admin0.00.10.40.5-0.4-0.50.10.40.4-0.40.4-0.1-0.5-0.50.5-0.1-0.10.3-0.10.1-0.6-0.0
Ambulatory time after self-admin0.10.10.40.4-0.2-0.20.30.60.6-0.60.60.1-0.2-0.20.20.20.20.10.2-0.2-0.30.2
Bone: tissue strength0.20.20.2-0.40.40.40.50.40.4-0.40.40.40.30.3-0.30.40.4-0.40.4-0.40.40.4
Total heroin consumption0.40.40.80.8-0.9-0.8-0.2-0.5-0.50.5-0.5-0.6-0.9-0.90.9-0.6-0.60.8-0.50.5-0.8-0.5
Bone: trabecular number0.10.20.20.4-0.4-0.4-0.4-0.5-0.50.5-0.5-0.5-0.4-0.40.4-0.5-0.50.4-0.50.5-0.4-0.5
Bone: trabecular spacing0.00.00.00.0-0.1-0.10.1-0.0-0.00.0-0.00.0-0.1-0.10.10.00.00.10.0-0.0-0.10.0
Bone: trabecular thickness0.10.10.20.3-0.2-0.4-0.4-0.4-0.40.4-0.4-0.4-0.4-0.40.4-0.4-0.40.2-0.40.4-0.5-0.4
Bone: trabecular tissue density11.820.621.04.5-4.5-4.6-4.5-4.6-4.64.6-4.6-4.6-4.5-4.54.5-4.6-4.64.5-4.64.6-4.6-4.6
Water consumed over 24 hours0.00.00.10.2-0.2-0.2-0.00.10.1-0.10.1-0.0-0.2-0.20.2-0.0-0.00.2-0.00.0-0.3-0.0
Number of responses in last shaping day0.20.30.40.5-0.5-0.5-0.7-0.7-0.70.7-0.7-0.5-0.3-0.30.3-0.5-0.50.5-0.50.5-0.4-0.5