Hub : Genes

Catsperz

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Catsperz 0.44 0.17 0.0e+00 0.34 0.33 0.34 0.32 8.8e-19 1.6e-18 5.8e-19 1.6e-17
2 OFC intron excision ratio chr1_204115773_204115970 0.15 0.09 3.5e-03 0.12 0.11 0.08 0.1 7.0e-04 1.2e-03 7.3e-03 2.6e-03
3 OFC mRNA stability Catsperz 0.4 0.14 5.6e-09 0.37 0.32 0.34 0.34 1.1e-09 3.0e-08 5.3e-09 6.7e-09
4 Brain mRNA stability Catsperz 0.16 0.08 2.2e-16 0.16 0.16 0.16 0.16 1.1e-14 4.9e-15 2.3e-14 3.6e-15
5 PL mRNA stability Catsperz 0.22 0.1 0.0e+00 0.27 0.24 0.25 0.25 3.0e-29 1.7e-26 3.8e-27 1.5e-27
6 IL mRNA stability Catsperz 0.22 0.12 1.3e-04 0.12 0.13 0.11 0.1 7.9e-04 6.3e-04 1.5e-03 2.3e-03
7 NAcc mRNA stability Catsperz 0.04 0.02 8.4e-06 0.05 0.04 0.04 0.04 2.0e-06 1.6e-05 3.9e-05 1.1e-05
8 PL gene expression Catsperz 0.05 0.03 3.4e-03 0.02 0.01 0.01 0.02 2.8e-03 9.1e-03 9.9e-03 3.7e-03
9 OFC intron excision ratio chr1_204115773_204117462 0.14 0.09 6.0e-03 0.03 0.06 0.09 0.06 6.2e-02 1.7e-02 3.7e-03 1.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.71.23.8-1.3-0.7-0.81.0-0.80.9-0.9-1.9-0.9
Area under the delay curve0.30.31.2-0.6-0.10.10.2-0.10.30.2-1.0-1.1
BMI with tail3.812.428.0-3.3-3.1-2.83.8-3.23.4-3.0-5.3-3.2
BMI without tail2.55.29.8-2.7-2.2-1.62.5-2.32.4-1.9-3.1-1.1
Body weight4.016.721.2-4.0-4.2-4.14.6-4.44.4-4.4-4.1-1.6
Weight adjusted by age2.22.43.6-1.8-1.9-1.71.9-1.81.6-1.5-0.80.3
Bone surface4.07.19.3-2.7-2.7-2.83.0-2.92.6-2.9-2.8-0.2
Bone volume1.52.64.7-1.6-1.5-1.61.8-1.61.4-1.7-2.2-0.4
Breakpoint value in progressive ratio session2.62.84.0-2.0-1.8-1.91.8-1.91.8-1.8-0.60.9
Number of licking bursts0.20.20.4-0.5-0.5-0.50.5-0.60.5-0.6-0.10.1
Context. condit. distance diff. score1.41.72.61.21.51.6-1.41.5-1.21.20.0-1.3
Locomotion velocity, session 10.10.20.6-0.4-0.1-0.20.20.00.3-0.0-0.8-0.7
Locomotion distance, session 10.81.03.3-1.1-0.5-0.70.8-0.40.9-0.6-1.8-1.4
Locomotion velocity, session 22.42.83.8-1.7-1.8-1.91.9-1.71.9-1.7-1.4-0.3
Locomotion distance, session 20.60.81.6-1.3-0.7-0.90.9-0.71.0-0.6-1.2-0.6
Locomotion velocity, session 31.41.68.30.10.80.5-0.40.8-0.40.6-2.0-2.9
Locomotion distance, session 30.10.20.90.10.20.3-0.10.3-0.10.1-0.5-1.0
Stereotopy head waving bouts, day 31.41.66.00.31.00.8-0.61.0-0.71.1-1.9-2.4
Stereotopy head waving duration, day 30.91.01.80.91.10.9-0.91.1-1.01.1-0.7-1.3
Locomotion velocity, session 71.01.13.50.11.00.8-0.71.1-0.81.0-1.2-1.9
Locomotion distance, session 70.50.62.6-0.70.50.4-0.30.6-0.10.6-1.0-1.6
Stereotopy head waving bouts, day 70.10.10.30.50.40.3-0.30.4-0.50.2-0.4-0.2
Stereotopy head waving duration, day 70.81.01.9-0.7-1.1-1.21.1-1.11.0-1.4-0.80.2
Locomotion velocity, session 80.91.12.1-1.4-0.9-1.11.0-0.91.3-0.9-1.00.3
Locomotion distance, session 80.40.62.4-0.20.50.5-0.20.6-0.20.4-1.6-1.4
Degree of sensitization distance0.50.52.1-0.50.40.1-0.10.3-0.10.6-1.2-1.4
Degree of sensitization stereotypy0.30.40.8-0.3-0.6-0.80.7-0.60.5-0.9-0.50.3
Conditioned locomotion1.31.52.3-1.5-1.3-1.41.3-1.51.4-1.2-0.70.1
Cocaine response after cond. corrected1.21.42.10.71.51.4-1.31.1-1.11.3-0.3-1.4
Cocaine response after cond. not corrected0.80.91.50.41.11.2-1.00.9-0.80.9-0.5-1.2
Cocaine response before conditioning0.81.01.4-0.8-1.2-0.91.1-1.00.9-1.2-0.11.1
Saline control response3.85.06.5-2.5-2.5-2.32.5-2.52.5-2.4-1.10.4
Bone: connectivity density2.64.15.7-2.4-2.0-1.92.2-2.02.0-2.1-2.3-0.8
Bone: cortical apparent density0.30.41.2-0.4-0.6-0.50.3-0.50.4-0.51.01.1
Bone: cortical area0.50.81.2-0.4-1.0-1.01.1-1.10.9-1.0-0.6-0.2
Bone: cortical porosity0.10.10.40.1-0.1-0.30.1-0.10.2-0.10.10.6
Bone: cortical porosity0.50.50.8-0.5-0.7-0.90.7-0.70.7-0.8-0.00.9
Bone: cortical thickness2.23.65.2-1.8-2.3-2.12.0-2.22.1-2.20.31.1
Bone: cortical thickness0.50.61.2-1.1-0.8-0.80.7-0.71.0-0.7-0.10.2
Bone: cortical tissue density0.40.51.4-0.5-0.6-0.70.4-0.60.5-0.61.01.2
Condit. Reinf. active minus inactive responses0.10.10.4-0.7-0.4-0.30.4-0.40.4-0.3-0.00.1
Condit. Reinf. active-inactive response ratio0.20.20.9-0.2-0.2-0.10.1-0.20.1-0.10.80.9
Condit. Reinf. active responses0.00.00.2-0.3-0.1-0.00.1-0.00.0-0.0-0.2-0.4
Condit. Reinf. inactive responses0.30.31.30.10.40.3-0.20.5-0.30.3-0.9-1.1
Incentive salience index mean0.30.40.7-0.8-0.6-0.50.7-0.60.6-0.5-0.6-0.6
Condit. Reinf. lever presses0.40.51.0-0.7-0.7-0.60.8-0.70.6-0.6-1.0-0.8
Condit. Reinf. active minus inactive responses0.10.20.40.50.40.4-0.40.3-0.60.2-0.00.4
Condit. Reinf. active-inactive response ratio0.60.61.41.00.90.9-0.70.8-1.20.7-0.4-0.0
Condit. Reinf. active responses0.00.10.20.0-0.2-0.10.2-0.30.0-0.3-0.10.5
Condit. Reinf. inactive responses0.30.40.7-0.7-0.8-0.60.7-0.80.9-0.60.00.3
Condit. Reinf. lever presses1.72.43.1-1.6-1.7-1.71.8-1.71.5-1.8-1.10.5
Condit. Reinf. lever reinforcers received0.20.30.6-0.3-0.6-0.50.5-0.70.3-0.60.00.8
Conditioned reinforcement - actives0.50.50.80.80.70.4-0.70.7-0.80.60.40.9
Conditioned reinforcement - inactives6.27.013.53.72.72.8-2.92.5-2.92.62.0-0.7
Conditioned locomotion9.411.319.24.43.63.3-3.73.5-3.73.52.4-1.0
Patch foraging indifference point 0 sec0.10.10.30.50.30.2-0.30.4-0.3-0.10.5-0.5
Patch foraging indifference point AUC3.23.75.3-2.1-2.2-2.12.2-2.32.1-2.1-0.60.9
Delay disc. indifference point, 0s delay0.60.62.9-0.50.20.50.10.40.10.4-1.7-1.4
Delay disc. indifference point, 16s delay1.01.01.71.10.91.1-0.91.0-1.01.00.2-1.3
Delay disc. indifference point, 2s delay0.20.21.2-0.0-0.10.30.20.10.00.5-1.1-0.6
Delay disc. indifference point, 24s delay0.10.10.3-0.3-0.00.2-0.10.00.10.20.4-0.5
Delay disc. indifference point, 4s delay0.30.31.5-0.6-0.20.30.3-0.00.30.1-0.9-1.2
Delay disc. indifference point, 8s delay0.20.20.6-0.80.10.10.0-0.10.30.0-0.8-0.6
Indifference point function ln k6.99.713.83.03.73.6-3.63.6-3.23.30.7-1.9
Indifference point function log k6.99.713.83.03.73.6-3.63.6-3.23.30.7-1.9
Patch foraging total patch changes 0 sec0.10.10.50.40.20.1-0.30.3-0.2-0.20.7-0.3
Patch foraging total patch changes 12 sec4.25.48.9-2.6-2.6-2.62.5-2.52.6-3.0-0.80.0
Patch foraging total patch changes 18 sec0.70.91.4-0.9-1.2-0.81.1-1.20.9-1.2-0.20.7
Patch foraging total patch changes 24 sec2.32.85.2-1.3-1.9-1.91.8-2.01.9-2.3-0.1-0.5
Patch foraging total patch changes 6 sec0.81.11.7-1.3-1.0-1.21.1-1.01.2-1.1-0.8-0.6
Patch foraging time to switch 0 sec1.72.64.2-1.7-1.6-1.71.9-1.31.6-1.3-2.1-0.9
Patch foraging water rate 0 sec3.86.19.53.12.52.8-2.72.3-2.62.32.50.1
Patch foraging water rate 12 sec7.010.815.43.93.63.7-3.83.2-3.43.32.7-0.7
Patch foraging water rate 18 sec2.53.44.81.92.22.1-2.21.9-1.92.10.9-0.9
Patch foraging water rate 24 sec2.94.16.42.52.22.5-2.31.9-2.22.01.4-0.3
Patch foraging water rate 6 sec3.45.07.72.32.42.8-2.52.3-2.32.41.6-0.8
Seeking ratio, delayed vs. immediate footshock0.20.21.11.00.10.3-0.20.5-0.40.50.4-0.4
Distance traveled before self-admin0.40.51.0-0.5-0.7-1.00.7-0.70.6-1.0-0.3-0.2
Distance traveled after self-admin0.10.20.30.2-0.2-0.50.1-0.40.2-0.50.50.6
Extensor digitorum longus weight6.726.334.3-5.3-5.7-5.85.9-5.75.8-5.6-3.3-0.3
Bone: elastic displacement1.21.42.21.31.11.1-1.31.3-1.01.31.50.3
Bone: elastic work0.50.61.2-0.8-0.9-0.90.8-0.91.1-0.90.0-0.1
Bone: endosteal estimation1.12.57.01.01.41.3-0.91.2-1.11.5-2.2-2.6
Bone: endosteal perimeter1.22.64.61.41.61.4-1.11.4-1.51.5-2.1-2.1
Epididymis fat weight2.25.28.62.92.42.7-2.12.3-2.41.8-0.6-2.6
Delta time in closed arm before/after self-admin0.50.53.6-0.60.1-0.10.10.20.3-0.0-0.6-1.9
Delta time in open arm before/after self-admin0.30.30.70.3-0.6-0.30.4-0.60.1-0.40.70.9
Diff in mean of infusions in LGA sessions0.40.40.7-0.8-0.7-0.60.5-0.80.6-0.80.50.6
Delay discount exponential model param0.20.20.90.60.2-0.1-0.30.2-0.3-0.10.80.9
Extinction: sum of active levers before priming4.34.35.7-2.2-2.4-2.32.4-2.32.3-2.1-1.20.5
Active lever presses in extinction session 62.32.23.0-1.7-1.6-1.71.5-1.61.5-1.7-0.11.1
Bone: final force2.74.35.7-1.9-2.2-2.32.4-2.32.2-2.2-1.9-0.6
Bone: final moment2.33.85.1-1.8-2.1-2.22.3-2.22.1-2.1-1.8-0.6
Food consumed during 24 hour testing period0.20.31.10.5-0.3-0.20.1-0.4-0.0-0.21.10.8
Glucose1.82.74.01.11.92.0-1.61.9-1.71.9-0.9-1.4
Heart weight2.94.25.72.02.42.4-2.22.3-2.12.10.3-1.6
Delay discount hyperbolic model param0.30.31.00.60.2-0.0-0.40.2-0.4-0.11.01.0
Intermittent access intake day 1-15 change0.90.91.51.20.70.9-0.90.7-1.00.41.21.2
Intermittent access intake escalation0.70.71.21.10.70.8-0.80.7-0.90.31.00.8
Intermittent access intake escalation 20.40.41.40.80.30.4-0.50.3-0.6-0.11.20.8
Intermitt. access day 1 inactive lever presses2.42.53.71.91.81.7-1.71.7-1.81.80.7-0.3
Intermitt. access day 15 inactive lever presses3.33.66.62.62.01.8-2.02.0-2.21.80.9-1.4
Intermitt. access escalation Index2.82.44.32.11.51.8-1.51.6-1.41.70.4-1.6
Intermittent access day 1 total infusions5.86.78.93.02.92.6-2.52.7-2.62.7-0.8-2.9
Intermittent access day 15 total infusions7.88.814.83.83.43.3-3.23.2-3.32.80.6-1.5
Intermittent access terminal intake (last 3 days)5.35.811.53.42.62.7-2.42.5-2.72.0-0.2-2.0
Intermittent access total infusions4.95.58.62.92.72.5-2.42.5-2.52.2-0.3-2.0
Intermittent access day 1 locomotion4.34.610.52.12.22.1-1.92.1-1.82.0-1.1-3.2
Intermittent access day 15 total locomotion4.75.19.03.02.52.5-2.42.2-2.52.00.4-1.8
Intermittent access total locomotion6.47.311.03.32.92.9-2.52.7-2.82.4-0.6-3.2
Intermittent access standard deviation1.21.32.41.61.21.2-1.31.2-1.40.60.90.5
Left kidney weight0.51.52.91.71.21.5-1.21.2-1.31.10.3-1.0
Right kidney weight0.20.62.71.60.50.6-0.50.5-0.80.10.2-0.7
Cocaine induced anxiety0.00.00.1-0.3-0.1-0.10.1-0.30.1-0.0-0.10.0
Post-drug Anxiety0.91.01.5-1.2-1.0-1.21.0-1.11.0-1.2-0.50.6
Baseline Anxiety1.92.04.0-1.4-1.5-1.61.5-1.51.6-2.0-0.50.4
Tail length0.92.85.3-2.3-1.8-1.61.6-1.91.8-1.80.21.3
Length with tail1.86.69.8-2.6-2.8-2.92.7-3.02.9-3.1-0.90.3
Length without tail1.43.05.1-1.3-1.7-2.21.8-1.91.9-2.2-1.1-0.7
Times rat made contact with spout0.50.61.3-1.1-0.7-0.70.6-0.80.8-0.60.30.8
Lifetime Intake4.24.86.62.62.52.3-2.22.4-2.32.0-0.5-2.1
Liver weight, left0.20.31.5-0.60.20.20.00.3-0.10.5-1.2-0.1
Liver weight, right0.40.73.4-0.30.20.30.10.10.20.4-1.5-1.8
Locomotor activity1.42.34.01.51.82.0-1.81.6-1.61.40.9-0.4
Locomotor testing distance1.93.25.11.52.12.3-2.22.0-1.71.90.9-0.9
Locomotor testing rearing1.52.43.51.41.91.9-1.81.8-1.61.50.6-0.7
Locomotion in novel chamber4.25.29.33.12.52.5-2.42.5-2.72.10.8-0.8
Locomotion in novel chamber post-restriction2.83.44.92.22.02.0-2.02.1-2.12.00.8-0.1
Fecal boli incidents, locomotor time 10.10.10.40.1-0.4-0.30.4-0.40.1-0.3-0.30.7
Change in fecal boli incidents, locomotor task0.20.20.5-0.50.20.1-0.00.30.20.5-0.7-0.6
Time >=10cm from walls, locomotor time 10.50.51.80.50.60.7-0.30.7-0.80.6-1.4-0.3
Bouts of movement, locomotor time 11.82.06.5-0.4-1.1-1.30.6-1.10.8-1.42.02.5
Total resting periods, locomotor time 11.41.54.9-0.2-0.9-1.00.5-0.90.6-1.41.92.2
Rest time, locomotor task time 11.61.82.41.31.21.3-1.41.3-1.41.61.50.9
Distance moved, locomotor task time 10.50.51.5-0.4-0.5-0.30.6-0.50.6-0.9-1.2-0.9
Vertical activity count, locomotor time 11.11.11.71.31.31.3-1.11.2-1.10.8-0.3-0.9
Time >=10cm from walls, locomotor time 20.20.21.60.1-0.3-0.40.2-0.3-0.1-0.30.41.3
Bouts of movement, locomotor time 20.30.30.6-0.3-0.7-0.70.5-0.60.6-0.80.60.3
Total resting periods, locomotor time 20.10.10.3-0.1-0.4-0.40.3-0.40.3-0.50.40.2
Rest time, locomotor task time 22.12.43.91.51.81.8-1.62.0-1.81.90.1-0.3
Distance moved, locomotor task time 21.21.42.4-1.0-1.2-1.21.1-1.31.2-1.60.21.1
Vertical activity count, locomotor time 20.20.20.80.20.00.2-0.20.00.00.10.90.8
Light reinforcement 10.10.20.50.20.40.4-0.50.5-0.5-0.10.70.5
Light reinforcement 21.21.62.91.71.51.0-1.41.5-1.61.10.6-0.5
Bone: marrow area1.22.67.01.01.51.3-1.01.3-1.21.5-2.2-2.6
Bone: maximum diameter0.20.41.0-0.0-0.5-0.60.7-0.70.4-0.6-1.0-0.4
Bone: maximum force3.25.68.7-2.2-2.3-2.42.7-2.42.3-2.3-2.9-1.4
Bone: maximum moment2.84.87.6-2.0-2.2-2.22.5-2.22.2-2.1-2.8-1.3
Mean time between licks in bursts0.40.51.3-1.2-0.6-0.70.6-0.61.1-0.7-0.0-0.3
Mean num. licks in bursts0.10.20.30.10.40.4-0.50.4-0.30.50.50.5
Cd content in liver1.01.12.31.50.91.2-1.00.6-1.21.10.80.5
Co content in liver1.61.95.41.11.21.3-1.51.1-1.11.32.31.2
Cu content in liver0.30.30.5-0.5-0.7-0.60.6-0.70.5-0.40.40.7
Fe content in liver0.30.30.5-0.6-0.6-0.40.7-0.70.5-0.4-0.70.2
K content in liver2.42.34.6-2.0-1.3-1.21.6-1.41.5-1.1-2.2-1.1
Mg content in liver0.50.52.0-0.6-0.1-0.20.4-0.20.3-0.0-1.3-1.4
Mn content in liver1.82.03.0-1.0-1.7-1.71.6-1.71.4-1.7-0.50.6
Na content in liver0.90.91.6-1.0-1.1-1.31.1-1.01.0-1.0-0.7-0.0
Rb content in liver1.41.72.51.01.61.5-1.41.4-1.41.6-0.3-1.0
Se content in liver0.10.10.30.6-0.20.10.2-0.2-0.30.00.10.2
Sr content in liver2.72.54.0-1.1-1.9-2.01.6-1.81.7-2.00.40.7
Zn content in liver1.01.11.8-0.7-1.3-1.31.2-1.11.1-1.3-0.2-0.5
Bone: minimum diameter1.12.06.31.11.21.1-0.81.1-1.11.2-1.8-2.5
Time in familiar zone, hab. session 10.30.30.90.50.60.5-0.50.4-0.40.5-0.2-1.0
Time in novel zone, hab. session 10.10.10.30.00.40.4-0.40.5-0.20.40.20.2
Total zone transitions, hab. session 10.40.61.1-0.7-0.8-1.10.8-0.80.8-1.0-0.30.2
Total locomotion distance, hab. session 10.40.51.40.60.70.6-0.50.7-0.60.7-0.7-1.2
Locomotion velocity, hab. session 10.10.10.50.20.20.1-0.10.2-0.20.2-0.5-0.7
Time in familiar zone, hab. session 20.10.10.5-0.70.10.2-0.1-0.10.40.00.10.0
Time in novel zone, hab. session 20.10.10.10.4-0.2-0.30.3-0.1-0.0-0.1-0.2-0.4
Total zone transitions, hab. session 21.41.72.9-1.3-1.1-1.41.4-1.11.4-1.3-1.7-1.2
Total locomotion distance, hab. session 20.40.52.9-0.00.10.00.20.20.10.2-1.4-1.7
Locomotion velocity, hab. session 20.40.62.70.30.30.3-0.00.4-0.20.4-1.4-1.6
Novel to familiar place preference ratio1.11.22.1-0.8-1.3-1.21.3-1.31.0-1.4-0.50.2
Novelty place preference0.50.51.1-0.5-0.9-0.80.9-0.90.6-1.0-0.30.2
Time in novel zone, NPP test0.40.51.0-0.5-0.8-0.70.8-0.80.5-1.0-0.3-0.0
Total zone transitions, NPP test2.13.03.9-1.9-1.8-2.01.9-1.81.9-2.0-1.5-0.0
Total locomotion distance, NPP test0.20.31.5-0.3-0.0-0.20.30.00.2-0.1-1.2-1.0
Locomotion velocity, NPP test0.10.10.7-0.2-0.1-0.30.3-0.10.2-0.0-0.8-0.5
Intraocular pressure1.62.25.92.10.71.3-1.10.7-1.40.82.41.6
Delta distance traveled before/after self-admin0.10.10.10.30.30.3-0.30.1-0.10.20.30.3
Delta ambulatory time before/after self-admin0.00.00.2-0.10.20.2-0.20.00.00.20.10.5
Parametrial fat weight1.63.15.81.32.02.1-1.71.8-1.71.5-0.9-2.4
Pavlov. Cond. lever latency0.40.50.80.40.80.6-0.80.8-0.70.60.80.9
Pavlov. Cond. magazine entry latency0.40.51.0-0.4-0.7-0.50.8-0.70.6-0.7-0.9-1.0
Pavlov. Cond. change in total contacts0.00.10.10.2-0.3-0.20.3-0.3-0.0-0.2-0.0-0.0
Pavlov. Cond. index score0.20.20.4-0.0-0.7-0.50.6-0.70.4-0.5-0.0-0.1
Pavlov. Cond. latency score0.10.20.3-0.1-0.5-0.30.5-0.50.4-0.4-0.3-0.4
Pavlov. Cond. lever contacts0.10.10.5-0.1-0.3-0.10.3-0.30.3-0.1-0.4-0.7
Pavlov. Cond. magazine entry number0.30.40.60.10.80.6-0.70.8-0.40.8-0.4-0.6
Pavlov. Cond. intertrial magazine entries1.01.23.01.30.90.9-1.10.9-1.10.81.71.0
Pavlov. Cond. lever-magazine prob. diff.0.40.50.9-0.2-0.9-0.70.9-0.90.7-0.8-0.2-0.1
Pavlov. Cond. response bias0.10.20.30.2-0.6-0.40.5-0.60.3-0.50.2-0.1
Pavlov. Cond. lever latency0.50.61.10.50.80.8-0.90.9-0.71.00.90.3
Pavlov. Cond. magazine entry latency3.43.96.4-2.0-2.2-2.22.2-2.42.2-2.5-0.80.4
Pavlov. Cond. change in total contacts1.31.73.3-0.5-1.6-1.61.5-1.61.1-1.8-0.50.6
Pavlov. Cond. index score2.12.74.9-1.3-1.9-1.81.9-2.01.6-2.2-0.90.3
Pavlov. Cond. latency score1.82.24.1-1.2-1.6-1.61.7-1.81.5-2.0-1.10.0
Pavlov. Cond. lever contacts0.40.61.3-0.6-0.9-0.80.8-0.90.6-1.2-0.20.5
Pavlov. Cond. magazine entry number5.46.610.42.22.93.0-2.93.0-2.73.21.0-0.6
Pavlov. Cond. intertrial magazine entries0.81.11.81.21.01.3-1.01.1-1.21.30.40.5
Pavlov. Cond. lever-magazine prob. diff.2.63.35.7-1.5-2.1-2.02.1-2.21.9-2.4-0.90.4
Pavlov. Cond. response bias1.52.13.8-1.2-1.7-1.61.6-1.71.4-2.0-0.50.6
Time in closed arm before self-admin0.10.10.4-0.1-0.2-0.20.3-0.40.2-0.1-0.20.6
Time in closed arm after self-admin0.20.20.30.00.50.3-0.40.5-0.30.6-0.2-0.6
Time in open arm before self-admin0.40.40.70.10.70.8-0.70.9-0.40.50.2-0.8
Time in open arm after self-admin0.30.31.30.50.10.3-0.30.1-0.20.21.10.8
Bone: periosteal estimation0.40.83.40.40.20.10.20.0-0.10.2-1.8-1.8
Bone: periosteal perimeter0.20.41.90.1-0.2-0.40.5-0.40.2-0.3-1.4-0.9
Bone: post-yield work1.21.710.2-0.5-0.3-0.50.8-0.40.2-0.1-3.2-1.8
Progressive ratio test 1 active lever presses3.43.55.52.32.11.9-2.12.0-2.12.10.9-0.1
Progressive ratio test 1 breakpoint2.93.15.32.31.91.8-1.91.8-2.02.00.80.1
Progressive ratio test 1 inactive lever presses1.31.42.71.61.31.2-1.31.1-1.20.80.6-1.0
Progressive ratio test 2 active lever presses4.95.39.03.02.52.4-2.52.4-2.62.40.8-1.0
Progressive ratio test 2 breakpoint6.37.011.33.42.92.8-2.92.8-3.02.91.4-0.6
Progressive ratio test 2 inactive lever presses8.69.920.44.53.43.4-3.43.1-3.52.91.3-1.6
Incentive Sensitization - Responses0.70.71.51.20.90.8-0.90.7-0.90.60.2-1.0
Incentive Sensitization - Breakpoint1.11.12.21.51.11.0-1.10.9-1.20.90.4-1.0
Sum of active levers in priming session hrs 5-61.41.33.4-0.6-1.1-1.30.8-1.20.7-1.21.01.9
Progressive ratio2.63.04.3-1.8-1.8-1.72.0-1.61.7-1.8-2.1-0.2
Food seeking constrained by brief footshock0.20.31.3-1.1-0.4-0.30.4-0.30.6-0.1-0.3-0.0
Seeking ratio, punishment vs. effort1.82.23.21.21.61.7-1.81.5-1.41.71.7-0.3
Retroperitoneal fat weight4.715.421.24.44.54.6-4.24.3-4.44.00.3-2.6
Reaction time number correct0.30.40.8-0.3-0.7-0.70.6-0.70.6-0.90.10.5
Reaction time mean minus median2.83.75.6-1.4-2.1-2.32.2-2.41.9-2.3-1.11.3
Reaction time mean minus median AUC1.72.23.6-0.9-1.6-1.61.6-1.91.4-1.8-0.51.5
Reaction time num false alarms0.30.50.90.10.80.7-0.90.9-0.40.70.8-0.0
Reaction time num false alarms AUC0.10.10.3-0.50.1-0.0-0.20.10.2-0.00.50.2
Reaction time trials correct on left0.30.40.8-0.3-0.7-0.70.6-0.70.6-0.90.10.5
Reaction time trials on left0.30.50.9-0.3-0.8-0.80.7-0.80.7-1.00.10.6
Reaction time mean0.10.10.60.5-0.1-0.30.1-0.3-0.1-0.40.00.8
Reaction time mean AUC0.10.10.60.6-0.0-0.20.0-0.2-0.1-0.40.10.8
Median of all reaction times0.10.10.70.80.40.2-0.40.2-0.50.00.10.2
Reaction time omissions0.81.12.2-0.7-0.9-1.30.8-1.11.0-1.5-0.11.2
Reaction time false alarm rate0.20.30.6-0.00.70.6-0.70.8-0.30.70.4-0.4
Reaction time premature initiation rate2.22.96.2-2.5-1.8-2.01.8-1.72.1-1.1-0.9-0.8
Reaction time premature initiations3.14.47.3-2.7-2.4-2.52.3-2.32.6-1.7-0.50.1
Std. dev. reaction times0.71.02.4-0.4-0.9-1.20.9-1.10.7-1.1-0.11.6
Reaction time trials completed0.30.50.9-0.3-0.8-0.80.7-0.80.7-1.00.10.6
Reaction time trials AUC0.20.30.6-0.2-0.6-0.60.5-0.60.6-0.80.00.4
Run reversals in cocaine runway, females1.31.34.9-1.2-0.3-0.60.6-0.40.9-0.7-1.7-2.2
Run reversals in cocaine runway, males0.20.10.50.70.10.6-0.10.2-0.30.40.10.5
Latency to leave start box in cocaine runway0.30.30.90.20.30.3-0.10.4-0.30.7-0.9-1.0
Latency to leave start box in cocaine runway, F0.00.00.20.1-0.1-0.00.2-0.0-0.00.1-0.3-0.4
Latency to leave start box in cocaine runway, M0.20.20.6-0.20.50.2-0.30.5-0.20.8-0.8-0.2
Std. dev. time between licks in bursts0.10.10.30.10.50.4-0.50.5-0.00.30.3-0.4
Total sessions with >9 infusions2.12.43.41.51.81.6-1.51.6-1.51.5-0.8-1.8
Short access day 1 total inactive lever presses4.75.26.72.62.62.4-2.52.6-2.52.50.8-1.5
Short access day 10 total inactive lever presses3.53.95.62.12.22.2-2.22.2-2.12.41.2-0.7
Short access day 1 total infusions3.13.34.71.92.21.8-1.92.0-1.91.9-0.4-1.7
Short access day 10 total infusions2.22.45.41.21.61.4-1.21.7-1.41.4-1.5-2.3
Short access total infusions1.82.03.81.21.61.3-1.31.5-1.31.3-1.1-2.0
Short access day 1 locomotion2.72.97.71.71.91.7-1.61.6-1.41.2-0.7-2.8
Short access day 10 total locomotion1.92.15.31.51.51.5-1.31.4-1.31.2-0.4-2.3
Short access total locomotion2.22.27.61.41.51.3-1.31.3-1.21.2-0.8-2.8
One hour access (0.3 mA shock)10.011.718.84.33.73.8-3.73.7-3.83.61.4-1.4
Compulsive drug intake2.42.54.7-2.2-1.8-1.71.6-1.51.8-1.40.50.9
One hour access (shock baseline)9.010.518.64.33.73.5-3.63.4-3.73.11.2-0.7
Social response proportion0.80.91.3-1.1-1.1-1.11.1-1.01.0-0.7-0.60.3
Social responses0.50.71.3-0.7-1.1-0.71.0-0.80.8-0.70.01.1
Social time0.50.61.2-0.7-0.9-0.70.8-0.90.8-0.7-0.21.1
Soleus weight3.610.614.03.43.73.7-3.73.7-3.63.61.3-0.8
Bone: stiffness2.43.85.0-2.1-2.0-2.12.2-2.11.9-2.0-2.1-0.3
Tibialis anterior weight9.632.743.5-5.8-6.5-6.56.5-6.66.3-6.5-2.41.1
Time to tail flick, vehicle, before self-admin1.31.33.3-1.2-0.9-0.91.1-1.10.9-0.7-1.8-1.3
Time to tail flick, vehicle, after self-admin3.13.35.4-2.1-1.7-1.32.0-1.82.1-1.6-2.3-1.1
Time to tail flick, test, before self-admin1.21.15.40.61.00.9-0.70.8-0.50.4-0.9-2.3
Time to tail flick, test, after self-admin0.10.10.2-0.2-0.4-0.10.4-0.30.3-0.5-0.30.5
Delta time to tail flick, vehicle, before/after SA0.80.81.3-1.1-0.9-0.61.0-0.81.1-0.8-1.00.1
Delta time to tail flick, test, before/after SA1.91.76.2-0.8-1.3-1.21.0-1.20.9-0.91.12.5
Tibia length0.72.13.5-0.8-1.9-1.71.8-1.91.3-1.7-0.40.8
Ambulatory time before self-admin0.30.31.2-0.0-0.6-0.70.6-0.60.3-1.1-0.00.1
Ambulatory time after self-admin0.20.21.11.10.40.2-0.40.3-0.50.20.3-0.2
Bone: tissue strength0.10.10.4-0.00.0-0.0-0.10.1-0.2-0.00.30.6
Total heroin consumption5.36.29.1-3.0-2.7-2.72.6-2.82.7-2.7-0.61.6
Bone: trabecular number0.60.92.3-0.8-0.8-0.81.1-0.90.8-1.0-1.5-0.8
Bone: trabecular spacing0.30.41.30.20.50.5-0.70.7-0.40.71.10.5
Bone: trabecular thickness0.50.50.80.70.90.8-0.80.9-0.90.6-0.4-0.4
Bone: trabecular tissue density3.14.45.72.42.32.4-2.42.3-2.42.11.40.7
Water consumed over 24 hours0.70.91.3-0.6-1.1-1.00.9-1.11.0-0.90.80.9
Number of responses in last shaping day1.21.31.91.31.31.2-1.41.1-1.10.71.0-0.7