Scn8a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr7_134004549_134004813 0.02 0.02 5.6e-03 -0 0 0.01 0 4.0e-01 4.8e-02 2.2e-02 3.6e-01
2 BLA mRNA stability Scn8a 0.04 0.03 6.4e-03 0.01 0.02 0 0.01 9.5e-02 2.6e-02 2.9e-01 6.2e-02
3 NAcc alternative polyA XM_063263132.1 0.03 0.02 8.9e-06 0.03 0.03 0.03 0.03 4.8e-05 1.2e-05 8.5e-05 2.5e-05
4 NAcc alternative polyA XM_063263132.1 0.03 0.02 2.4e-05 0.03 0.03 0.02 0.03 5.2e-05 1.7e-05 1.5e-04 4.7e-05
5 Brain mRNA stability Scn8a 0.03 0.02 1.8e-03 0.01 0.01 0.01 0.01 1.9e-02 7.3e-02 3.0e-02 8.2e-02
6 NAcc alternative TSS XM_063263135.1 0.02 0.01 2.8e-03 0.02 0.01 0.02 0.01 1.7e-03 2.0e-03 1.6e-03 2.6e-03
7 NAcc isoform ratio XM_063263132.1 0.02 0.02 9.5e-03 0.01 0.01 0 0.01 8.2e-03 8.6e-03 1.4e-01 9.8e-03
8 PL mRNA stability Scn8a 0.03 0.02 2.4e-03 0.02 0.02 0.01 0.01 1.3e-03 4.3e-03 1.6e-02 8.5e-03
9 Adipose gene expression Scn8a 0.66 0.09 0.0e+00 0.62 0.61 0.61 0.61 5.4e-88 1.1e-86 1.3e-85 1.2e-86
10 Adipose alternative polyA NM_019266.3 0.29 0.11 0.0e+00 0.29 0.27 0.29 0.28 4.0e-32 1.5e-29 2.7e-32 1.3e-30
11 Adipose isoform ratio XM_063263135.1 0.1 0.05 1.9e-08 0.07 0.07 0.07 0.07 1.3e-08 7.0e-08 2.0e-08 7.3e-08
12 Adipose alternative polyA NM_019266.3 0.3 0.12 0.0e+00 0.28 0.26 0.3 0.28 4.0e-31 5.6e-29 9.6e-34 7.3e-31
13 Adipose alternative polyA XM_063263132.1 0.28 0.11 0.0e+00 0.27 0.26 0.27 0.26 3.1e-30 3.0e-28 1.8e-30 8.1e-29
14 Adipose alternative polyA XM_063263132.1 0.3 0.12 0.0e+00 0.28 0.26 0.3 0.27 9.6e-31 1.6e-28 4.0e-33 3.0e-30
15 Adipose isoform ratio NM_019266.3 0.27 0.11 0.0e+00 0.24 0.23 0.25 0.24 6.5e-27 2.6e-25 2.6e-27 3.2e-26
16 Adipose isoform ratio XM_063263133.1 0.05 0.04 5.5e-04 0.01 0.01 0.01 0 1.9e-02 3.6e-02 1.3e-02 1.4e-01
17 NAcc isoform ratio XM_063263135.1 0.02 0.02 1.7e-03 0.01 0.01 0.01 0.01 3.7e-03 3.0e-03 6.7e-03 7.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.30.53.21.81.5-0.8-0.8-0.7-0.1-0.3-0.5-0.7-0.30.2-0.30.20.3-0.20.00.3
Area under the delay curve0.10.20.60.40.7-0.5-0.5-0.80.6-0.2-0.4-0.1-0.20.4-0.20.20.2-0.2-0.3-0.2
BMI with tail1.34.613.03.13.6-2.6-2.5-1.22.4-2.0-1.3-2.1-2.01.8-1.91.91.9-1.8-1.0-1.2
BMI without tail0.31.63.41.61.8-1.3-1.2-0.30.8-1.4-0.6-1.4-1.41.4-1.41.31.3-1.3-1.2-0.4
Body weight0.62.510.82.83.3-2.1-2.0-0.71.3-1.1-0.6-1.5-1.21.3-1.21.21.2-1.1-0.6-0.1
Weight adjusted by age1.13.34.61.91.8-1.8-1.9-2.12.0-1.6-2.0-1.5-1.71.9-1.71.71.7-1.7-1.8-1.9
Bone surface0.30.63.61.91.9-1.0-0.9-0.50.2-0.5-0.3-0.6-0.40.2-0.30.30.3-0.20.10.4
Bone volume0.51.04.32.12.0-1.2-1.1-0.80.3-0.9-0.6-1.1-0.70.5-0.60.60.6-0.5-0.20.1
Breakpoint value in progressive ratio session0.10.10.50.20.3-0.0-0.00.20.10.40.30.10.3-0.60.3-0.3-0.30.30.70.3
Number of licking bursts0.00.10.2-0.4-0.3-0.2-0.1-0.40.1-0.1-0.3-0.1-0.30.3-0.30.30.3-0.3-0.4-0.5
Context. condit. distance diff. score0.10.10.30.10.10.20.20.4-0.30.20.50.20.2-0.40.2-0.2-0.20.20.20.5
Locomotion velocity, session 11.11.22.5-1.5-1.61.31.20.7-0.60.70.91.31.2-1.01.1-1.1-1.11.11.00.5
Locomotion distance, session 10.20.31.2-1.1-1.10.70.60.2-0.20.60.30.30.3-0.40.3-0.3-0.30.20.3-0.2
Locomotion velocity, session 20.60.71.1-0.9-0.90.80.80.5-0.71.10.61.01.0-0.80.9-1.0-0.90.90.70.6
Locomotion distance, session 20.50.82.8-1.7-1.51.00.90.5-0.61.20.50.60.7-0.90.6-0.6-0.60.60.80.1
Locomotion velocity, session 32.83.25.8-2.4-2.32.02.01.9-1.82.01.61.81.7-1.61.6-1.6-1.61.61.21.4
Locomotion distance, session 33.54.06.8-2.0-2.32.32.21.9-2.62.21.71.81.9-1.81.9-1.9-1.91.81.42.0
Stereotopy head waving bouts, day 31.72.03.00.71.1-1.4-1.4-1.31.7-1.4-1.1-1.5-1.51.4-1.51.61.5-1.5-1.4-1.7
Stereotopy head waving duration, day 30.10.10.3-0.40.0-0.3-0.30.10.6-0.50.0-0.4-0.40.3-0.40.50.4-0.4-0.3-0.5
Locomotion velocity, session 72.22.44.2-1.9-2.01.81.81.9-2.11.31.21.21.3-1.51.3-1.3-1.31.31.11.4
Locomotion distance, session 73.84.86.9-2.6-2.62.42.42.2-2.32.42.12.22.0-2.12.0-2.0-2.02.01.81.9
Stereotopy head waving bouts, day 74.85.66.82.42.3-2.4-2.4-2.42.0-2.4-2.6-2.4-2.32.4-2.32.42.3-2.3-2.4-2.3
Stereotopy head waving duration, day 72.93.64.31.92.0-2.0-2.0-1.81.8-2.0-2.1-1.9-1.91.9-1.81.91.8-1.8-1.8-1.9
Locomotion velocity, session 80.00.00.1-0.3-0.30.20.20.1-0.1-0.0-0.00.10.0-0.10.0-0.0-0.0-0.0-0.2-0.0
Locomotion distance, session 80.91.32.2-1.3-1.31.21.20.9-0.91.51.11.21.1-1.31.1-1.1-1.11.11.20.9
Degree of sensitization distance0.20.31.20.10.5-0.5-0.5-0.31.1-0.7-0.2-0.5-0.50.3-0.50.50.5-0.4-0.1-0.7
Degree of sensitization stereotypy3.74.15.72.32.1-2.1-2.1-2.21.8-1.9-2.4-2.0-1.92.0-1.91.91.9-1.9-2.0-2.0
Conditioned locomotion0.30.30.8-0.6-0.70.60.60.4-0.70.40.60.30.4-0.90.4-0.4-0.50.40.90.5
Cocaine response after cond. corrected0.20.20.50.00.3-0.4-0.4-0.30.5-0.7-0.5-0.4-0.50.5-0.50.50.5-0.5-0.6-0.6
Cocaine response after cond. not corrected0.00.00.2-0.3-0.20.00.00.10.0-0.4-0.2-0.1-0.10.1-0.20.20.2-0.2-0.4-0.2
Cocaine response before conditioning1.51.82.5-1.3-1.61.61.51.4-1.21.31.31.31.3-1.41.3-1.3-1.31.31.01.3
Saline control response0.20.30.7-0.5-0.60.70.70.8-0.90.10.70.20.4-0.60.4-0.4-0.40.40.30.8
Bone: connectivity density0.10.20.60.80.6-0.0-0.0-0.0-0.40.60.10.30.4-0.40.4-0.4-0.40.40.60.7
Bone: cortical apparent density1.42.23.10.50.7-1.2-1.2-1.21.5-1.7-1.1-1.7-1.71.4-1.71.71.7-1.7-1.5-1.8
Bone: cortical area0.50.83.31.71.8-1.1-1.1-0.60.6-1.1-0.6-0.8-0.70.6-0.60.60.6-0.6-0.4-0.0
Bone: cortical porosity0.90.91.4-0.6-0.70.90.90.9-1.10.60.80.91.1-1.11.1-1.1-1.11.11.11.2
Bone: cortical porosity1.11.21.8-0.8-0.91.11.11.1-1.30.71.00.91.2-1.21.2-1.2-1.21.21.21.3
Bone: cortical thickness0.20.41.51.01.2-0.9-0.8-0.40.6-0.8-0.5-0.6-0.50.4-0.50.50.5-0.4-0.3-0.2
Bone: cortical thickness0.40.50.9-0.8-0.70.80.80.8-1.00.80.70.70.6-0.70.6-0.6-0.60.60.50.8
Bone: cortical tissue density1.22.02.90.40.6-1.1-1.1-1.11.4-1.7-1.0-1.6-1.71.3-1.71.71.7-1.7-1.4-1.7
Condit. Reinf. active minus inactive responses0.00.00.20.10.1-0.1-0.1-0.10.40.2-0.0-0.10.10.10.0-0.1-0.00.1-0.0-0.2
Condit. Reinf. active-inactive response ratio0.20.20.3-0.1-0.10.30.30.5-0.20.50.40.40.5-0.40.5-0.5-0.50.50.30.5
Condit. Reinf. active responses0.00.00.3-0.2-0.10.0-0.0-0.30.50.3-0.1-0.10.2-0.10.1-0.2-0.10.20.2-0.4
Condit. Reinf. inactive responses0.10.10.6-0.7-0.60.10.1-0.40.4-0.1-0.1-0.3-0.0-0.0-0.00.00.1-0.00.1-0.6
Incentive salience index mean0.20.30.80.70.7-0.6-0.6-0.80.90.0-0.6-0.4-0.30.5-0.30.30.3-0.3-0.4-0.6
Condit. Reinf. lever presses0.91.42.61.41.5-1.4-1.4-1.61.6-0.6-1.3-1.0-1.01.0-1.01.01.0-0.9-0.7-1.3
Condit. Reinf. active minus inactive responses0.40.71.30.91.1-0.9-0.9-0.60.9-1.0-0.4-0.8-0.90.9-0.80.90.8-0.8-0.6-0.7
Condit. Reinf. active-inactive response ratio0.10.20.50.30.7-0.5-0.50.10.5-0.60.0-0.4-0.40.6-0.40.40.4-0.4-0.4-0.3
Condit. Reinf. active responses0.40.51.00.70.7-0.7-0.7-0.60.6-1.0-0.4-0.8-0.80.7-0.80.80.8-0.7-0.4-0.6
Condit. Reinf. inactive responses0.10.10.20.1-0.1-0.1-0.1-0.50.1-0.3-0.4-0.4-0.30.2-0.30.40.3-0.3-0.0-0.4
Condit. Reinf. lever presses0.81.11.5-1.0-0.91.01.01.2-1.11.11.21.21.0-1.11.0-1.0-1.01.01.01.2
Condit. Reinf. lever reinforcers received0.00.00.20.10.2-0.2-0.2-0.00.1-0.40.1-0.2-0.30.2-0.30.30.3-0.20.1-0.2
Conditioned reinforcement - actives0.20.61.3-1.1-1.00.80.80.8-0.90.50.70.60.7-0.90.7-0.7-0.70.70.70.6
Conditioned reinforcement - inactives0.61.73.9-2.0-1.91.51.51.3-1.51.11.11.11.1-1.21.1-1.1-1.11.00.80.9
Conditioned locomotion0.71.01.6-1.3-1.00.91.01.2-0.80.90.90.91.0-1.11.0-1.0-1.01.01.00.9
Patch foraging indifference point 0 sec0.51.44.3-1.7-2.11.81.71.2-1.71.10.90.90.8-0.60.8-0.7-0.70.70.21.0
Patch foraging indifference point AUC0.10.30.80.10.0-0.4-0.4-0.90.6-0.2-0.7-0.6-0.60.6-0.60.60.6-0.7-0.6-0.8
Delay disc. indifference point, 0s delay0.10.10.60.60.8-0.5-0.5-0.60.40.1-0.40.2-0.00.2-0.00.00.0-0.0-0.20.0
Delay disc. indifference point, 16s delay0.00.00.10.20.3-0.1-0.1-0.10.0-0.10.00.20.1-0.00.1-0.1-0.10.10.00.2
Delay disc. indifference point, 2s delay5.76.47.32.52.5-2.5-2.5-2.42.5-2.4-2.4-2.4-2.62.7-2.62.62.6-2.6-2.5-2.4
Delay disc. indifference point, 24s delay0.10.10.70.20.5-0.4-0.3-0.40.9-0.1-0.1-0.0-0.00.0-0.00.00.0-0.00.2-0.2
Delay disc. indifference point, 4s delay0.20.20.80.50.8-0.6-0.6-0.90.6-0.2-0.5-0.3-0.30.4-0.30.30.3-0.3-0.4-0.3
Delay disc. indifference point, 8s delay0.10.20.5-0.30.00.20.30.1-0.20.60.50.50.5-0.40.5-0.5-0.50.50.40.7
Indifference point function ln k0.10.31.71.11.3-0.8-0.7-0.10.7-0.5-0.2-0.2-0.20.2-0.20.20.2-0.10.10.1
Indifference point function log k0.10.31.71.11.3-0.8-0.7-0.10.7-0.5-0.2-0.2-0.20.2-0.20.20.2-0.10.10.1
Patch foraging total patch changes 0 sec0.72.05.1-1.9-2.32.01.91.5-1.81.31.21.11.0-0.81.0-1.0-1.00.90.51.2
Patch foraging total patch changes 12 sec0.40.62.6-1.3-1.61.21.10.4-0.80.50.70.40.4-0.30.4-0.4-0.40.30.30.3
Patch foraging total patch changes 18 sec0.40.93.5-1.6-1.91.41.30.7-1.41.10.40.70.6-0.20.6-0.5-0.50.50.10.5
Patch foraging total patch changes 24 sec0.20.62.0-1.0-1.41.11.10.4-1.11.10.40.40.5-0.40.5-0.4-0.50.40.10.5
Patch foraging total patch changes 6 sec0.50.93.4-1.6-1.91.41.30.6-1.00.80.60.70.6-0.70.6-0.6-0.60.50.20.4
Patch foraging time to switch 0 sec0.10.20.7-0.3-0.60.20.1-0.2-0.5-0.8-0.3-0.4-0.50.5-0.50.50.5-0.6-0.8-0.5
Patch foraging water rate 0 sec0.10.31.20.71.1-0.5-0.40.10.60.40.0-0.00.3-0.40.3-0.3-0.30.40.90.4
Patch foraging water rate 12 sec0.10.31.00.60.5-0.1-0.0-0.1-0.11.00.10.50.7-0.60.7-0.7-0.70.70.80.6
Patch foraging water rate 18 sec0.00.10.40.10.2-0.1-0.0-0.10.10.50.20.20.1-0.30.2-0.1-0.20.20.60.1
Patch foraging water rate 24 sec0.30.41.81.31.3-0.9-0.9-0.60.9-0.4-0.5-0.4-0.30.1-0.30.30.2-0.20.4-0.2
Patch foraging water rate 6 sec0.30.41.81.31.3-0.7-0.6-0.60.50.7-0.40.20.3-0.20.3-0.3-0.30.40.40.4
Seeking ratio, delayed vs. immediate footshock0.00.10.20.40.4-0.2-0.2-0.50.40.1-0.20.20.10.10.1-0.1-0.10.1-0.0-0.1
Distance traveled before self-admin0.20.41.1-1.0-1.10.80.70.5-0.60.60.50.50.5-0.50.5-0.4-0.40.40.40.3
Distance traveled after self-admin2.64.65.1-2.0-2.12.22.22.2-2.02.02.32.02.2-2.22.2-2.1-2.22.22.22.0
Extensor digitorum longus weight7.028.035.45.96.0-5.6-5.6-5.04.9-5.2-4.8-5.7-5.35.1-5.35.35.3-5.3-4.8-4.6
Bone: elastic displacement3.84.88.6-2.9-2.92.52.42.3-1.72.02.32.12.1-2.12.1-2.0-2.02.02.01.6
Bone: elastic work2.43.24.1-1.8-1.61.61.71.9-1.21.71.71.91.9-1.91.9-1.9-1.91.92.01.6
Bone: endosteal estimation0.20.53.11.71.6-0.8-0.7-0.1-0.1-0.50.0-0.5-0.20.2-0.10.10.1-0.10.00.6
Bone: endosteal perimeter0.51.24.72.22.0-1.3-1.3-0.70.3-1.2-0.6-1.1-0.80.8-0.80.80.8-0.8-0.80.0
Epididymis fat weight1.67.910.1-2.0-1.72.32.42.6-2.33.03.22.93.0-3.13.0-3.1-3.13.13.23.0
Delta time in closed arm before/after self-admin0.20.10.3-0.0-0.20.30.30.4-0.40.40.40.20.4-0.50.4-0.4-0.40.40.50.4
Delta time in open arm before/after self-admin2.53.03.6-1.8-1.81.91.81.6-1.91.61.91.71.7-1.71.7-1.7-1.71.71.71.7
Diff in mean of infusions in LGA sessions0.61.01.61.31.3-1.1-1.1-1.11.0-0.8-0.9-1.1-1.00.7-1.01.01.0-0.9-0.5-0.9
Delay discount exponential model param0.20.30.9-0.5-0.80.70.61.0-0.80.30.50.20.4-0.50.4-0.3-0.40.40.40.4
Extinction: sum of active levers before priming0.91.43.01.71.7-1.4-1.4-1.41.5-1.0-1.0-0.8-1.00.8-1.01.01.0-1.0-0.6-1.0
Active lever presses in extinction session 60.70.71.3-0.7-0.40.60.61.2-0.60.90.80.90.9-1.00.9-0.9-0.91.01.00.9
Bone: final force0.30.53.51.51.9-0.9-0.8-0.10.4-0.0-0.1-0.0-0.0-0.00.0-0.1-0.10.10.50.7
Bone: final moment0.30.53.31.51.8-0.8-0.70.10.20.00.00.00.1-0.20.2-0.2-0.20.30.60.9
Food consumed during 24 hour testing period0.51.02.5-0.30.00.50.60.9-0.41.21.01.11.1-1.31.2-1.2-1.21.21.61.1
Glucose0.10.10.3-0.5-0.40.40.40.2-0.10.40.30.30.4-0.40.4-0.4-0.40.40.50.2
Heart weight0.40.71.4-0.4-0.40.70.70.9-1.20.80.80.80.8-0.80.8-0.8-0.80.90.81.1
Delay discount hyperbolic model param0.30.41.1-0.6-0.90.80.81.1-0.90.40.60.40.5-0.60.5-0.5-0.50.60.60.5
Intermittent access intake day 1-15 change0.31.62.3-1.0-0.81.11.21.3-1.21.21.41.11.3-1.51.3-1.3-1.31.31.51.4
Intermittent access intake escalation0.10.61.0-0.4-0.30.60.60.7-0.80.70.90.60.8-0.90.8-0.8-0.80.81.01.0
Intermittent access intake escalation 20.40.71.0-0.4-0.50.70.70.8-1.01.00.61.00.9-0.80.9-0.9-0.90.90.71.0
Intermitt. access day 1 inactive lever presses0.00.10.3-0.3-0.0-0.1-0.10.30.5-0.2-0.2-0.3-0.20.2-0.20.20.2-0.2-0.1-0.4
Intermitt. access day 15 inactive lever presses0.00.10.3-0.4-0.40.30.30.6-0.10.30.20.30.3-0.20.3-0.3-0.30.30.10.3
Intermitt. access escalation Index0.82.53.51.61.3-1.6-1.6-1.91.7-1.3-1.9-1.4-1.51.5-1.51.51.5-1.5-1.7-1.8
Intermittent access day 1 total infusions0.20.72.2-1.4-1.21.01.01.5-1.00.50.90.50.5-0.50.5-0.5-0.50.50.30.6
Intermittent access day 15 total infusions0.30.71.9-1.1-1.00.91.01.4-1.10.51.10.50.6-0.70.6-0.6-0.60.60.50.9
Intermittent access terminal intake (last 3 days)0.30.62.0-1.1-1.00.90.91.4-1.10.40.90.40.5-0.50.4-0.4-0.40.40.30.8
Intermittent access total infusions0.60.72.2-1.4-1.11.01.01.5-1.10.41.00.40.4-0.40.4-0.4-0.40.40.20.8
Intermittent access day 1 locomotion0.81.43.3-1.8-1.51.31.31.6-1.20.91.41.00.9-1.00.9-0.9-0.90.90.81.0
Intermittent access day 15 total locomotion1.24.85.4-2.2-2.02.22.22.3-2.32.12.32.12.2-2.32.2-2.2-2.22.22.02.3
Intermittent access total locomotion2.53.06.3-2.5-2.11.91.92.1-1.81.41.91.41.5-1.61.5-1.5-1.51.51.41.6
Intermittent access standard deviation0.73.44.6-1.6-1.61.81.82.1-1.91.91.81.91.9-1.81.9-1.9-1.91.91.62.0
Left kidney weight0.10.52.71.61.5-0.9-0.8-0.50.2-0.3-0.4-0.4-0.40.7-0.40.40.4-0.4-0.50.2
Right kidney weight0.42.59.23.03.0-2.0-2.0-1.51.3-1.0-1.3-1.2-1.11.2-1.01.01.0-1.0-0.9-0.5
Cocaine induced anxiety0.00.10.60.80.6-0.2-0.10.3-0.2-0.00.1-0.00.1-0.10.1-0.1-0.10.20.30.5
Post-drug Anxiety0.30.30.80.40.40.10.10.6-0.40.40.40.40.6-0.70.6-0.6-0.60.60.80.9
Baseline Anxiety0.10.10.50.30.5-0.5-0.4-0.50.7-0.2-0.4-0.2-0.20.1-0.20.20.2-0.2-0.1-0.3
Tail length0.10.31.7-0.3-0.50.60.60.7-1.30.30.60.20.4-0.00.4-0.4-0.40.3-0.21.0
Length with tail0.00.21.21.01.1-0.5-0.4-0.1-0.2-0.00.2-0.4-0.10.4-0.00.00.0-0.0-0.20.6
Length without tail0.20.84.62.02.1-1.3-1.2-0.90.9-0.0-0.3-0.4-0.10.1-0.00.00.00.00.50.2
Times rat made contact with spout0.40.50.9-0.3-0.40.50.50.3-0.60.80.50.90.8-0.70.8-0.8-0.80.80.80.7
Lifetime Intake1.31.64.1-1.9-1.71.51.52.0-1.50.91.50.90.9-0.90.9-0.9-0.90.90.71.2
Liver weight, left0.30.53.51.71.9-1.0-0.9-0.00.0-0.1-0.3-0.1-0.10.1-0.10.10.1-0.00.00.6
Liver weight, right0.10.20.90.30.60.00.10.8-0.50.50.50.30.30.00.3-0.3-0.30.30.30.9
Locomotor activity0.20.30.9-1.0-0.90.70.60.6-0.60.80.30.80.5-0.30.5-0.4-0.40.40.10.3
Locomotor testing distance0.40.92.3-1.5-1.51.21.11.2-0.91.10.61.10.7-0.30.7-0.7-0.70.60.00.5
Locomotor testing rearing0.31.12.2-1.2-1.51.41.41.3-1.40.80.91.00.9-0.50.8-0.8-0.80.80.21.0
Locomotion in novel chamber1.01.34.02.01.8-1.4-1.3-0.80.9-1.0-1.0-1.0-1.01.1-1.01.01.0-0.9-1.0-0.5
Locomotion in novel chamber post-restriction0.20.71.4-0.8-0.50.60.70.8-0.50.81.10.70.9-1.10.9-0.9-0.90.91.20.9
Fecal boli incidents, locomotor time 11.23.34.0-1.9-1.71.81.82.0-1.61.81.92.01.8-1.81.8-1.8-1.81.81.71.7
Change in fecal boli incidents, locomotor task1.01.11.30.70.8-1.0-1.0-0.91.1-1.1-1.1-1.1-1.11.1-1.11.11.1-1.1-1.1-1.1
Time >=10cm from walls, locomotor time 10.40.51.3-1.1-0.90.80.81.0-0.80.20.90.40.5-0.50.5-0.5-0.50.50.50.6
Bouts of movement, locomotor time 10.10.10.5-0.20.1-0.2-0.2-0.70.30.2-0.50.20.2-0.10.1-0.2-0.10.20.0-0.4
Total resting periods, locomotor time 10.10.20.8-0.9-0.50.20.2-0.2-0.10.5-0.20.50.4-0.30.4-0.4-0.40.40.2-0.2
Rest time, locomotor task time 10.20.30.9-0.9-0.80.60.60.4-0.70.70.30.50.5-0.50.5-0.5-0.50.50.30.3
Distance moved, locomotor task time 10.10.30.70.40.4-0.5-0.5-0.20.8-0.7-0.4-0.5-0.60.6-0.50.60.5-0.6-0.5-0.5
Vertical activity count, locomotor time 10.21.21.91.41.3-1.1-1.1-0.71.0-1.4-0.9-1.3-1.21.1-1.11.11.1-1.1-0.9-0.8
Time >=10cm from walls, locomotor time 20.20.41.4-1.2-0.90.70.70.9-0.80.60.50.60.5-0.40.5-0.5-0.50.50.30.5
Bouts of movement, locomotor time 20.41.32.31.41.5-1.2-1.2-0.91.2-1.3-0.7-1.1-1.11.1-1.11.11.1-1.1-1.0-0.6
Total resting periods, locomotor time 20.52.13.41.71.8-1.5-1.5-1.31.5-1.6-1.0-1.4-1.41.5-1.41.41.4-1.4-1.4-1.0
Rest time, locomotor task time 20.00.00.1-0.1-0.1-0.1-0.1-0.20.2-0.2-0.1-0.2-0.20.1-0.20.20.2-0.2-0.1-0.3
Distance moved, locomotor task time 20.00.00.20.00.1-0.2-0.2-0.20.4-0.2-0.3-0.1-0.10.3-0.10.10.1-0.2-0.3-0.3
Vertical activity count, locomotor time 20.00.10.40.40.4-0.3-0.3-0.60.3-0.3-0.2-0.3-0.30.4-0.20.20.2-0.3-0.2-0.2
Light reinforcement 10.00.10.4-0.6-0.60.20.2-0.30.10.6-0.10.30.1-0.10.1-0.1-0.10.10.1-0.3
Light reinforcement 20.10.21.50.70.3-0.4-0.4-1.20.30.4-0.40.1-0.30.4-0.20.20.3-0.3-0.4-0.4
Bone: marrow area0.20.42.71.61.5-0.7-0.60.0-0.2-0.40.1-0.4-0.10.1-0.00.00.00.00.10.7
Bone: maximum diameter0.20.51.21.11.1-0.7-0.7-0.40.1-1.1-0.3-0.7-0.60.6-0.60.60.6-0.6-0.5-0.0
Bone: maximum force0.71.57.22.32.7-1.7-1.6-0.91.2-0.8-0.9-0.9-0.70.6-0.60.60.6-0.5-0.0-0.1
Bone: maximum moment0.61.26.72.32.6-1.6-1.4-0.60.9-0.7-0.7-0.7-0.50.4-0.40.40.4-0.30.20.2
Mean time between licks in bursts0.20.92.4-1.5-1.10.80.81.2-0.21.31.11.00.9-0.90.9-0.9-0.90.90.80.5
Mean num. licks in bursts0.41.01.6-0.3-0.40.90.91.0-0.90.91.01.01.1-1.11.1-1.1-1.11.11.21.3
Cd content in liver0.20.20.6-0.6-0.60.50.50.8-0.3-0.10.50.20.4-0.50.4-0.4-0.40.3-0.00.4
Co content in liver0.20.30.70.50.3-0.3-0.3-0.80.4-0.3-0.3-0.6-0.60.5-0.60.50.6-0.6-0.8-0.4
Cu content in liver0.10.10.70.5-0.00.20.2-0.0-0.9-0.10.20.10.10.10.1-0.1-0.10.1-0.20.5
Fe content in liver0.30.41.2-0.9-1.10.70.70.6-1.10.10.50.50.3-0.10.3-0.3-0.30.2-0.60.4
K content in liver0.00.00.10.2-0.00.00.0-0.2-0.3-0.3-0.20.0-0.10.3-0.10.10.1-0.1-0.3-0.0
Mg content in liver0.20.20.5-0.6-0.50.50.50.4-0.40.30.70.40.5-0.50.5-0.5-0.50.50.70.4
Mn content in liver0.20.20.90.40.4-0.5-0.5-0.90.4-0.2-0.8-0.6-0.40.3-0.40.40.4-0.40.1-0.7
Na content in liver0.10.10.60.60.10.10.1-0.5-0.70.3-0.30.50.10.30.1-0.1-0.10.1-0.40.3
Rb content in liver0.60.71.3-1.1-1.11.01.01.0-1.00.31.00.60.7-0.60.7-0.7-0.70.70.60.8
Se content in liver0.91.12.5-1.6-1.51.21.11.0-1.31.00.70.90.9-0.90.9-0.9-0.90.90.60.6
Sr content in liver0.20.10.30.60.10.20.1-0.0-0.50.5-0.40.40.4-0.30.4-0.4-0.40.40.20.5
Zn content in liver1.11.21.9-1.4-1.31.21.21.2-1.11.01.31.01.0-1.11.0-1.0-1.01.01.01.0
Bone: minimum diameter0.61.24.42.02.1-1.4-1.3-0.80.7-1.3-0.7-1.1-0.80.8-0.80.80.8-0.7-0.5-0.1
Time in familiar zone, hab. session 10.10.10.7-0.20.1-0.1-0.1-0.10.7-0.10.30.00.3-0.20.2-0.3-0.20.30.8-0.2
Time in novel zone, hab. session 10.60.61.90.50.4-0.5-0.5-0.40.1-0.7-0.6-0.7-1.00.8-1.01.01.0-1.1-1.4-0.5
Total zone transitions, hab. session 11.52.13.81.21.2-1.5-1.5-1.71.9-1.2-2.0-1.5-1.31.3-1.31.31.3-1.3-1.0-1.9
Total locomotion distance, hab. session 10.00.10.3-0.4-0.2-0.0-0.0-0.10.50.4-0.30.10.1-0.10.1-0.0-0.10.10.2-0.5
Locomotion velocity, hab. session 10.00.10.2-0.4-0.2-0.0-0.0-0.00.50.4-0.30.10.1-0.10.1-0.1-0.10.10.2-0.4
Time in familiar zone, hab. session 20.20.32.00.30.5-0.1-0.10.10.50.20.40.30.5-0.60.5-0.5-0.50.71.40.3
Time in novel zone, hab. session 20.40.42.0-0.3-0.4-0.0-0.1-0.1-0.3-0.6-0.3-0.7-0.80.7-0.80.80.8-0.9-1.4-0.5
Total zone transitions, hab. session 20.10.10.6-0.2-0.30.10.1-0.2-0.10.8-0.40.30.2-0.30.2-0.2-0.20.20.5-0.2
Total locomotion distance, hab. session 20.20.30.7-0.8-0.70.50.50.4-0.40.80.30.40.4-0.60.4-0.4-0.40.40.70.2
Locomotion velocity, hab. session 20.30.41.1-0.8-0.70.60.60.5-0.61.10.30.60.6-0.70.6-0.6-0.60.60.80.4
Novel to familiar place preference ratio1.92.53.61.91.8-1.7-1.7-1.71.4-1.0-1.9-1.6-1.51.5-1.51.51.5-1.5-1.7-1.4
Novelty place preference1.62.13.21.61.6-1.6-1.6-1.51.3-0.9-1.8-1.4-1.31.4-1.31.31.3-1.4-1.5-1.3
Time in novel zone, NPP test1.82.23.21.61.5-1.6-1.6-1.51.4-1.0-1.8-1.5-1.41.4-1.41.41.4-1.4-1.5-1.4
Total zone transitions, NPP test0.20.31.3-0.9-1.00.40.4-0.4-0.11.1-0.10.50.3-0.40.3-0.3-0.30.30.5-0.4
Total locomotion distance, NPP test1.01.43.7-1.9-1.81.21.20.5-0.81.90.81.31.0-1.11.0-1.0-1.01.01.30.4
Locomotion velocity, NPP test1.11.64.7-1.7-1.61.21.20.5-0.82.20.81.41.2-1.21.2-1.2-1.21.11.30.5
Intraocular pressure1.83.06.1-2.5-2.42.12.11.8-1.21.51.81.41.5-1.71.5-1.5-1.51.51.71.3
Delta distance traveled before/after self-admin4.95.46.5-1.7-1.82.22.22.4-2.32.22.52.32.5-2.42.5-2.5-2.52.52.52.5
Delta ambulatory time before/after self-admin3.05.16.0-1.7-1.82.22.22.4-2.42.12.42.22.4-2.32.4-2.4-2.42.42.32.4
Parametrial fat weight1.53.45.9-2.3-1.81.81.81.9-0.72.02.41.91.8-1.71.8-1.7-1.81.82.21.5
Pavlov. Cond. lever latency1.01.32.1-1.4-1.31.21.31.4-1.10.81.31.01.1-1.11.1-1.1-1.11.00.91.1
Pavlov. Cond. magazine entry latency1.82.33.11.71.8-1.6-1.6-1.51.3-1.4-1.4-1.5-1.61.5-1.61.61.6-1.5-1.5-1.2
Pavlov. Cond. change in total contacts3.03.24.52.12.1-2.0-1.9-1.91.8-1.2-1.8-1.7-1.81.8-1.81.81.8-1.7-1.5-1.6
Pavlov. Cond. index score3.14.05.72.42.2-2.1-2.1-2.21.7-1.6-2.1-1.8-2.02.0-2.02.02.0-1.9-1.9-1.7
Pavlov. Cond. latency score2.83.55.22.32.1-1.9-2.0-2.11.5-1.6-2.0-1.7-1.91.9-1.91.81.8-1.8-1.8-1.6
Pavlov. Cond. lever contacts1.11.32.21.51.3-1.2-1.2-1.40.9-0.8-1.3-1.0-1.11.1-1.11.11.1-1.1-0.9-1.0
Pavlov. Cond. magazine entry number1.21.62.1-1.4-1.41.31.31.2-1.01.01.11.21.3-1.31.3-1.3-1.31.31.41.0
Pavlov. Cond. intertrial magazine entries2.12.54.4-2.1-2.11.71.71.3-1.01.71.51.51.5-1.71.5-1.5-1.51.51.70.9
Pavlov. Cond. lever-magazine prob. diff.3.03.75.62.42.3-2.1-2.1-2.21.7-1.5-2.1-1.7-1.91.9-1.91.91.9-1.8-1.7-1.7
Pavlov. Cond. response bias0.70.91.31.11.1-1.0-1.0-1.00.8-0.5-0.9-0.8-1.00.9-1.01.01.0-0.9-0.8-0.8
Pavlov. Cond. lever latency1.52.13.61.91.6-1.4-1.4-1.51.3-1.6-1.7-1.5-1.41.4-1.41.41.4-1.4-1.2-1.3
Pavlov. Cond. magazine entry latency1.52.23.6-1.9-1.51.31.41.5-1.11.61.71.61.5-1.31.5-1.5-1.51.51.41.3
Pavlov. Cond. change in total contacts0.41.01.61.01.2-1.2-1.2-1.01.2-0.9-0.8-0.9-1.01.0-0.91.00.9-0.9-0.8-0.9
Pavlov. Cond. index score0.91.52.6-1.6-1.21.11.11.2-0.91.31.51.31.2-1.11.2-1.2-1.21.21.01.0
Pavlov. Cond. latency score0.81.32.5-1.6-1.21.01.11.2-0.91.21.41.31.1-1.01.1-1.1-1.11.10.91.0
Pavlov. Cond. lever contacts1.52.23.5-1.9-1.61.41.51.5-1.31.51.71.51.5-1.41.5-1.5-1.51.51.31.3
Pavlov. Cond. magazine entry number0.70.91.31.10.8-0.8-0.8-1.00.6-1.0-1.2-1.1-0.90.9-0.90.90.9-1.0-1.1-0.8
Pavlov. Cond. intertrial magazine entries1.02.23.3-1.4-1.71.81.81.7-1.81.51.51.31.2-1.41.2-1.2-1.21.21.01.6
Pavlov. Cond. lever-magazine prob. diff.0.61.01.8-1.3-1.00.80.91.0-0.71.11.21.11.0-0.91.0-1.0-1.01.00.90.8
Pavlov. Cond. response bias1.92.63.9-2.0-1.51.41.51.6-1.11.91.91.71.6-1.51.6-1.6-1.61.61.61.4
Time in closed arm before self-admin1.93.34.12.01.9-1.9-1.9-1.61.6-1.9-1.9-1.9-1.81.9-1.71.71.7-1.8-1.8-1.7
Time in closed arm after self-admin1.82.13.11.61.4-1.5-1.5-1.41.4-1.4-1.5-1.8-1.41.4-1.41.41.4-1.4-1.3-1.5
Time in open arm before self-admin0.60.71.40.10.4-0.7-0.8-0.81.2-0.8-0.9-0.7-0.90.8-0.90.90.9-0.9-0.8-1.1
Time in open arm after self-admin0.20.20.7-0.9-0.60.50.50.5-0.20.20.50.60.4-0.40.4-0.4-0.40.40.40.3
Bone: periosteal estimation0.41.04.92.22.2-1.3-1.2-0.40.2-1.0-0.5-0.9-0.50.5-0.50.40.4-0.4-0.30.4
Bone: periosteal perimeter1.22.36.22.52.5-1.8-1.7-1.10.9-1.8-1.0-1.6-1.31.2-1.31.31.3-1.2-1.2-0.4
Bone: post-yield work0.10.21.51.11.2-0.6-0.6-0.10.00.2-0.2-0.1-0.1-0.1-0.10.10.1-0.00.30.4
Progressive ratio test 1 active lever presses2.23.99.5-3.1-2.72.32.22.3-1.91.42.31.41.6-1.91.5-1.5-1.51.51.61.4
Progressive ratio test 1 breakpoint2.54.29.9-3.1-2.82.42.32.4-2.01.52.51.51.7-2.01.6-1.6-1.61.71.81.5
Progressive ratio test 1 inactive lever presses0.00.10.9-1.0-0.50.30.30.5-0.10.10.30.00.1-0.30.1-0.1-0.10.10.00.1
Progressive ratio test 2 active lever presses0.40.62.7-1.6-1.10.90.91.3-1.00.30.90.40.3-0.40.3-0.3-0.30.30.20.6
Progressive ratio test 2 breakpoint0.30.42.1-1.4-0.90.70.71.0-0.80.20.60.20.1-0.20.1-0.1-0.10.1-0.00.4
Progressive ratio test 2 inactive lever presses0.51.63.4-1.8-1.41.41.41.8-1.31.01.41.01.1-1.11.0-1.0-1.01.00.91.3
Incentive Sensitization - Responses0.20.71.00.71.0-0.8-0.8-0.60.5-0.8-0.9-0.8-0.91.0-0.90.80.9-0.9-1.0-0.5
Incentive Sensitization - Breakpoint0.40.81.30.81.0-0.9-0.9-0.70.6-0.9-1.0-0.9-1.01.1-1.00.91.0-1.0-1.1-0.6
Sum of active levers in priming session hrs 5-60.10.10.1-0.20.1-0.2-0.2-0.20.4-0.2-0.3-0.2-0.30.2-0.30.30.3-0.3-0.1-0.4
Progressive ratio0.10.21.3-1.1-1.00.60.60.4-0.40.40.40.40.3-0.30.3-0.2-0.30.20.20.1
Food seeking constrained by brief footshock0.70.92.5-1.6-1.51.11.10.8-0.80.80.90.70.8-0.90.8-0.8-0.80.80.70.5
Seeking ratio, punishment vs. effort0.00.00.10.20.1-0.0-0.0-0.10.10.00.00.00.1-0.10.1-0.1-0.10.10.10.1
Retroperitoneal fat weight2.712.316.3-3.7-3.33.53.53.5-2.64.03.93.83.5-3.13.5-3.5-3.53.53.63.2
Reaction time number correct0.20.61.50.2-0.10.60.60.9-1.20.90.50.60.7-1.00.7-0.7-0.80.81.11.2
Reaction time mean minus median0.10.72.4-1.3-1.51.21.10.6-1.40.20.70.70.5-0.70.4-0.4-0.40.40.30.3
Reaction time mean minus median AUC0.00.21.0-0.7-1.00.70.60.1-0.8-0.20.30.20.2-0.70.2-0.2-0.20.20.4-0.1
Reaction time num false alarms0.00.10.5-0.7-0.60.30.2-0.10.3-0.20.10.0-0.00.2-0.00.10.0-0.1-0.2-0.3
Reaction time num false alarms AUC0.10.20.5-0.6-0.50.00.0-0.40.7-0.3-0.2-0.2-0.20.5-0.30.30.3-0.3-0.5-0.7
Reaction time trials correct on left0.20.61.50.2-0.10.60.60.9-1.20.90.50.60.7-1.00.7-0.7-0.80.81.11.2
Reaction time trials on left0.20.71.60.2-0.20.70.70.9-1.31.00.50.60.8-1.00.8-0.8-0.80.81.11.2
Reaction time mean0.10.30.6-0.7-0.80.70.60.8-0.8-0.20.70.20.3-0.50.3-0.3-0.30.30.30.5
Reaction time mean AUC0.10.20.4-0.5-0.60.60.50.7-0.7-0.20.60.10.2-0.40.2-0.2-0.20.20.30.4
Median of all reaction times0.10.20.7-0.4-0.40.40.40.8-0.4-0.20.60.00.2-0.30.2-0.2-0.20.20.20.5
Reaction time omissions0.71.24.4-1.8-2.11.51.41.0-1.40.60.70.80.8-0.90.8-0.8-0.70.70.50.4
Reaction time false alarm rate0.60.82.1-0.3-0.0-0.6-0.6-1.01.4-0.9-0.7-0.7-0.81.2-0.80.90.9-0.9-1.2-1.4
Reaction time premature initiation rate1.32.03.7-1.7-1.91.61.61.0-1.31.91.31.31.3-1.31.3-1.3-1.31.31.11.0
Reaction time premature initiations1.02.95.2-1.5-1.81.91.91.4-1.92.31.51.61.6-1.71.7-1.6-1.71.61.61.6
Std. dev. reaction times0.10.51.9-1.2-1.41.00.90.4-1.00.10.60.50.3-0.50.3-0.3-0.30.30.30.1
Reaction time trials completed0.20.71.60.2-0.20.70.70.9-1.31.00.50.60.8-1.00.8-0.8-0.80.81.11.2
Reaction time trials AUC0.10.41.00.40.10.40.40.7-1.00.70.30.40.6-0.80.6-0.6-0.60.60.91.0
Run reversals in cocaine runway, females0.10.10.40.3-0.10.30.30.5-0.60.00.60.20.2-0.30.2-0.2-0.20.30.40.6
Run reversals in cocaine runway, males1.51.62.70.80.7-1.0-1.0-1.10.8-1.5-1.3-1.6-1.51.3-1.51.51.5-1.5-1.5-1.3
Latency to leave start box in cocaine runway0.40.61.30.10.6-0.8-0.8-0.81.2-0.7-1.0-0.3-0.70.9-0.70.70.7-0.7-0.9-1.0
Latency to leave start box in cocaine runway, F0.30.41.0-0.30.1-0.4-0.5-0.80.8-0.6-0.8-0.4-0.60.6-0.60.60.6-0.6-0.7-1.0
Latency to leave start box in cocaine runway, M0.50.51.10.91.1-0.9-0.9-0.60.8-0.4-0.8-0.2-0.50.9-0.50.50.5-0.5-0.8-0.5
Std. dev. time between licks in bursts0.50.91.6-1.1-1.31.01.00.5-0.81.10.81.01.1-1.01.0-1.1-1.01.00.80.6
Total sessions with >9 infusions0.60.83.5-1.9-1.31.01.01.3-0.70.60.80.60.5-0.60.5-0.5-0.50.50.30.5
Short access day 1 total inactive lever presses0.40.72.2-1.5-1.21.01.01.1-0.70.60.90.60.6-0.70.6-0.6-0.60.60.60.6
Short access day 10 total inactive lever presses0.00.10.30.60.3-0.2-0.2-0.10.0-0.1-0.5-0.1-0.30.5-0.30.30.3-0.3-0.6-0.1
Short access day 1 total infusions1.01.93.8-1.9-1.61.51.52.0-1.61.11.51.11.1-1.21.1-1.1-1.11.20.91.4
Short access day 10 total infusions0.30.52.0-1.4-1.20.90.81.4-1.00.20.70.20.2-0.20.2-0.2-0.20.2-0.10.4
Short access total infusions2.12.96.1-2.4-2.22.02.02.5-2.01.31.91.41.3-1.41.3-1.3-1.31.31.11.5
Short access day 1 locomotion0.10.21.2-1.1-0.70.50.50.7-0.40.20.60.30.3-0.40.2-0.2-0.20.30.20.4
Short access day 10 total locomotion0.10.31.0-1.0-0.80.70.71.0-1.00.20.70.10.2-0.30.2-0.2-0.20.20.20.6
Short access total locomotion0.60.92.6-1.6-1.31.11.11.3-1.00.61.10.60.7-0.80.6-0.6-0.60.70.60.8
One hour access (0.3 mA shock)0.10.10.30.40.4-0.2-0.20.6-0.1-0.4-0.0-0.3-0.20.1-0.20.20.2-0.2-0.20.1
Compulsive drug intake0.50.71.20.91.0-0.9-0.9-0.71.1-0.9-0.7-0.8-0.80.8-0.80.80.8-0.8-0.6-0.8
One hour access (shock baseline)0.00.10.40.10.10.10.10.6-0.5-0.00.2-0.00.1-0.10.1-0.1-0.10.1-0.10.4
Social response proportion1.21.52.4-1.2-1.11.21.21.5-1.31.31.31.41.3-0.81.3-1.3-1.31.20.81.4
Social responses0.20.31.4-1.2-1.10.60.60.6-0.30.80.10.20.3-0.30.3-0.3-0.20.2-0.3-0.1
Social time0.60.91.8-0.6-0.60.80.91.2-0.91.20.81.41.0-0.51.0-1.0-1.01.00.51.2
Soleus weight0.00.10.70.80.7-0.3-0.3-0.30.10.00.30.1-0.00.20.0-0.0-0.0-0.0-0.20.3
Bone: stiffness2.03.611.93.23.4-2.5-2.4-1.81.7-1.5-1.5-1.7-1.51.4-1.51.41.4-1.3-0.9-0.7
Tibialis anterior weight9.633.139.35.96.0-5.9-5.9-5.45.4-6.0-5.2-6.3-6.05.4-6.06.05.9-5.9-5.2-5.3
Time to tail flick, vehicle, before self-admin0.10.10.6-0.7-0.60.40.40.5-0.40.20.10.40.20.20.1-0.1-0.10.1-0.40.1
Time to tail flick, vehicle, after self-admin0.40.71.20.50.9-0.9-0.9-0.30.8-0.7-1.0-1.1-0.90.9-0.90.90.9-0.9-0.9-0.8
Time to tail flick, test, before self-admin0.30.30.70.60.2-0.4-0.4-0.80.5-0.5-0.6-0.8-0.50.4-0.50.50.5-0.5-0.3-0.7
Time to tail flick, test, after self-admin0.30.30.70.80.7-0.5-0.5-0.30.2-0.5-0.5-0.8-0.50.6-0.50.50.5-0.6-0.5-0.3
Delta time to tail flick, vehicle, before/after SA0.00.00.20.20.4-0.2-0.20.30.0-0.0-0.0-0.3-0.1-0.2-0.10.10.00.00.20.1
Delta time to tail flick, test, before/after SA0.00.00.20.00.2-0.1-0.00.4-0.2-0.10.00.1-0.10.3-0.10.10.1-0.1-0.30.2
Tibia length0.20.62.40.50.9-0.00.11.1-0.80.71.10.30.6-0.80.6-0.6-0.70.71.01.5
Ambulatory time before self-admin0.30.81.9-1.2-1.41.11.00.5-0.81.00.80.80.8-0.90.8-0.7-0.80.80.80.5
Ambulatory time after self-admin3.35.35.9-2.1-2.42.42.42.2-2.42.12.42.22.3-2.42.3-2.3-2.32.32.32.2
Bone: tissue strength0.40.41.00.81.0-0.8-0.7-0.61.0-0.4-0.5-0.7-0.50.3-0.50.50.5-0.4-0.0-0.5
Total heroin consumption0.40.51.3-0.2-0.10.40.40.6-0.20.80.90.80.7-1.00.7-0.7-0.70.81.10.8
Bone: trabecular number0.20.30.80.90.60.00.00.0-0.50.50.30.20.5-0.50.6-0.6-0.60.60.90.9
Bone: trabecular spacing0.20.30.6-0.20.0-0.4-0.4-0.30.6-0.6-0.4-0.5-0.60.6-0.60.60.6-0.6-0.7-0.7
Bone: trabecular thickness0.71.01.81.31.0-1.0-1.0-1.30.8-0.9-1.2-1.2-0.80.9-0.80.80.8-0.8-0.6-0.9
Bone: trabecular tissue density2.74.85.91.72.1-2.4-2.3-2.12.4-2.4-2.1-2.0-2.22.1-2.22.22.2-2.2-1.9-2.4
Water consumed over 24 hours0.81.62.6-0.8-0.91.31.31.1-1.61.11.31.31.3-1.51.3-1.3-1.31.31.41.5
Number of responses in last shaping day0.10.20.50.00.3-0.4-0.4-0.30.5-0.7-0.3-0.7-0.40.1-0.40.40.4-0.4-0.3-0.5