Ovol1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	LHb	gene expression	Ovol1	0.15	0.09	5.5e-03	0.07	0.05	0.04	0.03	8.1e-03	2.6e-02	4.9e-02	8.3e-02
2	pVTA	gene expression	Ovol1	0.12	0.07	4.0e-04	0.04	0.06	0.05	0.04	6.2e-03	1.1e-03	3.3e-03	5.5e-03
3	Brain	gene expression	Ovol1	0.36	0.15	1.4e-12	0.08	0.11	0.12	0.12	4.4e-08	4.4e-10	2.1e-11	2.7e-11
4	NAcc	gene expression	Ovol1	0.09	0.04	1.5e-10	0.05	0.09	0.08	0.08	3.9e-06	2.1e-10	5.2e-10	6.2e-10
5	Adipose	gene expression	Ovol1	0.12	0.07	5.0e-08	0.04	0.04	0.04	0.03	7.0e-05	4.3e-05	7.5e-05	1.4e-04
6	BLA	gene expression	Ovol1	0.25	0.12	9.5e-08	0.13	0.14	0.13	0.13	1.6e-07	1.1e-07	2.7e-07	2.0e-07
7	PL	gene expression	Ovol1	0.31	0.12	0.0e+00	0.27	0.28	0.28	0.28	5.1e-30	6.3e-31	6.1e-31	3.0e-31
8	RMTg	gene expression	Ovol1	0.45	0.16	5.2e-04	0.05	0.05	0.04	0.08	1.9e-02	2.2e-02	2.7e-02	2.9e-03
9	OFC	gene expression	Ovol1	0.34	0.17	1.7e-03	0.17	0.06	0.12	0.14	6.3e-05	1.5e-02	8.3e-04	3.4e-04
10	IL	gene expression	Ovol1	0.33	0.16	3.8e-04	0.14	0.13	0.13	0.1	3.6e-04	4.8e-04	4.7e-04	2.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	1.6	2.7	4.6	0.8	-1.5	1.5	-1.8	-2.1	-1.8	-1.9	0.2	2.1	1.6
Area under the delay curve	0.5	0.5	1.6	-0.4	-0.3	0.7	-0.6	-0.6	-0.6	-1.1	-0.5	0.8	1.3
BMI with tail	6.9	22.4	29.8	3.0	-4.6	4.8	-5.1	-5.3	-5.4	-5.5	-1.1	5.2	5.4
BMI without tail	3.5	7.2	9.6	1.5	-2.5	3.0	-2.8	-2.7	-3.0	-3.1	-1.2	3.1	3.1
Body weight	3.4	14.2	21.2	4.3	-4.6	3.9	-4.4	-4.0	-4.2	-3.4	-1.8	2.9	3.2
Weight adjusted by age	0.8	1.0	2.8	1.7	-1.4	1.3	-1.1	-1.0	-0.8	-0.3	-0.1	0.3	0.3
Bone surface	3.6	6.4	10.7	2.8	-3.1	2.5	-3.1	-3.3	-2.5	-2.2	0.6	2.0	1.9
Bone volume	2.0	3.5	6.8	1.6	-2.0	1.8	-2.2	-2.6	-1.7	-1.8	1.2	1.8	1.5
Breakpoint value in progressive ratio session	1.7	1.9	4.8	2.2	-1.8	1.8	-1.6	-1.5	-1.0	-0.8	0.1	0.7	0.4
Number of licking bursts	0.2	0.2	0.4	0.6	-0.6	0.6	-0.6	-0.6	-0.3	-0.2	0.2	0.2	0.2
Context. condit. distance diff. score	0.7	0.9	3.2	-1.8	1.4	-1.0	1.1	0.9	0.6	0.2	0.2	0.3	-0.5
Locomotion velocity, session 1	0.1	0.1	0.8	0.0	0.1	-0.2	0.2	0.5	-0.1	0.1	-0.9	-0.4	-0.3
Locomotion distance, session 1	1.7	2.2	3.4	0.9	-1.4	1.6	-1.6	-1.4	-1.9	-1.8	-1.0	1.7	1.3
Locomotion velocity, session 2	2.9	3.4	4.8	2.0	-2.2	2.2	-2.1	-1.9	-2.1	-1.8	-0.9	1.5	1.3
Locomotion distance, session 2	1.7	2.3	3.3	1.2	-1.5	1.7	-1.6	-1.4	-1.8	-1.8	-1.2	1.4	1.5
Locomotion velocity, session 3	0.5	0.6	1.6	-0.2	-0.2	0.3	-0.5	-0.6	-1.1	-1.2	-0.3	1.1	1.2
Locomotion distance, session 3	0.0	0.0	0.0	-0.1	0.1	-0.1	0.1	0.1	-0.1	-0.1	-0.1	-0.1	0.1
Stereotopy head waving bouts, day 3	0.5	0.6	1.6	-1.0	0.2	-0.1	-0.1	-0.1	-0.9	-1.1	-0.6	0.7	1.2
Stereotopy head waving duration, day 3	0.2	0.3	1.5	-1.2	0.6	-0.5	0.3	0.2	-0.1	-0.4	-0.1	0.3	0.4
Locomotion velocity, session 7	1.2	1.4	4.2	-0.4	-0.2	0.8	-0.6	-1.1	-1.0	-1.7	0.5	2.0	1.7
Locomotion distance, session 7	0.6	0.8	1.9	0.0	-0.3	0.7	-0.6	-0.6	-1.0	-1.2	-0.8	1.4	1.1
Stereotopy head waving bouts, day 7	0.3	0.3	1.7	-0.6	0.1	-0.0	-0.1	-0.5	0.1	-0.3	1.3	0.4	0.7
Stereotopy head waving duration, day 7	1.3	1.6	2.8	0.9	-1.4	1.4	-1.5	-1.7	-1.0	-1.2	0.6	1.3	1.4
Locomotion velocity, session 8	0.5	0.6	2.4	1.2	-0.9	0.4	-0.6	-0.0	-0.9	-0.2	-1.6	0.1	-0.3
Locomotion distance, session 8	0.2	0.4	1.0	-0.5	0.0	0.1	-0.2	-0.4	-0.7	-1.0	0.1	1.0	0.8
Degree of sensitization distance	0.7	0.7	1.7	0.0	-0.4	0.6	-0.7	-0.7	-1.1	-1.1	-0.4	1.3	0.9
Degree of sensitization stereotypy	0.6	0.7	1.4	0.6	-0.8	0.8	-0.9	-1.2	-0.3	-0.5	1.1	0.6	1.0
Conditioned locomotion	0.7	0.8	2.1	1.4	-1.2	0.9	-1.0	-0.7	-1.0	-0.6	-0.9	0.4	0.2
Cocaine response after cond. corrected	0.7	0.8	2.0	-1.4	1.2	-1.1	1.0	1.1	0.3	0.2	-0.9	-0.4	-0.1
Cocaine response after cond. not corrected	0.5	0.6	1.6	-1.3	1.0	-0.9	0.8	0.9	0.1	0.1	-0.7	-0.3	0.1
Cocaine response before conditioning	0.4	0.5	0.9	1.0	-0.9	0.8	-0.8	-0.8	-0.4	-0.2	0.7	0.3	0.7
Saline control response	2.7	3.5	6.2	2.5	-2.4	2.0	-2.2	-1.6	-2.1	-1.2	-1.5	1.1	1.4
Bone: connectivity density	3.2	5.0	7.3	2.0	-2.5	2.3	-2.7	-2.7	-2.4	-2.2	-0.3	2.5	1.7
Bone: cortical apparent density	0.1	0.2	0.7	0.6	-0.4	0.8	-0.3	-0.2	0.0	-0.1	-0.5	0.0	0.1
Bone: cortical area	0.2	0.4	1.6	1.3	-0.8	0.5	-0.6	-0.7	-0.4	-0.2	0.5	-0.1	0.2
Bone: cortical porosity	0.5	0.6	1.0	0.2	-0.7	0.9	-0.8	-0.9	-0.8	-0.8	-0.0	1.0	0.8
Bone: cortical porosity	0.8	0.9	1.5	0.7	-1.1	1.2	-1.1	-1.0	-1.0	-0.9	-0.4	0.9	0.7
Bone: cortical thickness	0.9	1.4	6.5	2.5	-1.5	1.3	-1.0	-0.4	-0.7	0.0	-1.5	-0.3	-0.4
Bone: cortical thickness	0.5	0.5	2.9	1.0	-0.4	0.2	-0.1	0.5	-0.2	0.3	-1.7	-0.5	-0.7
Bone: cortical tissue density	0.1	0.2	0.7	0.6	-0.5	0.8	-0.4	-0.2	0.0	-0.0	-0.6	-0.1	0.0
Condit. Reinf. active minus inactive responses	0.4	0.4	0.9	0.5	-0.6	0.9	-0.7	-0.6	-0.6	-0.7	-0.4	0.5	0.8
Condit. Reinf. active-inactive response ratio	0.0	0.0	0.3	0.2	-0.2	0.5	-0.2	-0.1	0.1	-0.1	-0.1	-0.0	0.2
Condit. Reinf. active responses	0.3	0.4	0.7	0.4	-0.5	0.8	-0.6	-0.7	-0.7	-0.8	0.2	0.8	0.7
Condit. Reinf. inactive responses	0.3	0.3	0.9	0.0	-0.2	0.2	-0.4	-0.7	-0.6	-0.8	0.7	0.9	0.6
Incentive salience index mean	1.0	1.2	1.9	0.7	-1.0	1.4	-1.1	-1.1	-1.2	-1.3	-0.3	1.2	1.4
Condit. Reinf. lever presses	0.6	0.7	1.1	0.7	-0.8	0.8	-0.8	-1.0	-1.0	-1.0	0.2	1.0	1.0
Condit. Reinf. active minus inactive responses	0.2	0.2	1.7	-0.3	0.2	-0.2	0.1	-0.3	0.3	0.2	1.3	-0.1	0.5
Condit. Reinf. active-inactive response ratio	0.7	0.7	4.5	-0.7	0.7	-0.8	0.5	-0.2	0.6	0.2	2.1	-0.3	0.7
Condit. Reinf. active responses	0.3	0.4	0.8	0.3	-0.5	0.6	-0.7	-0.9	-0.3	-0.5	0.6	0.6	0.9
Condit. Reinf. inactive responses	0.9	1.1	1.8	0.6	-1.0	1.4	-1.2	-0.9	-1.0	-1.0	-1.1	1.3	0.7
Condit. Reinf. lever presses	1.3	1.8	4.3	2.1	-1.8	1.3	-1.6	-1.8	-1.0	-0.7	0.7	0.7	0.7
Condit. Reinf. lever reinforcers received	0.4	0.5	1.1	0.6	-0.8	0.8	-0.9	-1.0	-0.3	-0.4	0.6	0.6	0.8
Conditioned reinforcement - actives	0.9	0.9	2.8	-0.3	0.8	-0.9	0.8	0.5	1.0	0.9	1.7	-0.8	-1.0
Conditioned reinforcement - inactives	5.4	6.0	9.0	-2.6	3.0	-2.6	2.8	2.0	2.9	2.1	2.8	-1.7	-1.6
Conditioned locomotion	7.8	9.4	14.0	-3.2	3.7	-3.7	3.5	3.0	3.3	2.7	2.3	-2.4	-2.5
Patch foraging indifference point 0 sec	0.0	0.0	0.1	-0.3	0.1	-0.2	0.0	-0.0	0.0	-0.1	0.2	0.1	-0.1
Patch foraging indifference point AUC	1.5	1.7	5.6	2.4	-1.9	1.5	-1.6	-1.4	-0.8	-0.5	0.1	0.3	0.0
Delay disc. indifference point, 0s delay	0.5	0.5	1.3	-1.0	0.1	0.5	-0.2	-0.2	-0.6	-1.1	-0.7	0.7	1.1
Delay disc. indifference point, 16s delay	0.2	0.3	0.8	-0.9	0.6	-0.3	0.3	-0.2	0.5	-0.4	0.7	0.1	0.5
Delay disc. indifference point, 2s delay	0.0	0.0	0.2	-0.2	0.1	-0.1	-0.0	-0.1	-0.1	-0.3	0.2	0.0	0.4
Delay disc. indifference point, 24s delay	0.2	0.2	1.0	-0.5	0.3	0.0	0.3	0.6	0.1	0.0	-1.0	-0.3	0.0
Delay disc. indifference point, 4s delay	0.4	0.5	1.3	-0.6	-0.1	0.6	-0.3	-0.1	-0.6	-0.8	-1.1	0.6	1.1
Delay disc. indifference point, 8s delay	0.3	0.3	1.1	-0.5	-0.2	0.3	-0.4	-0.2	-0.6	-0.7	-1.0	0.6	0.8
Indifference point function ln k	3.9	5.5	14.2	-3.8	3.3	-2.8	2.9	2.8	1.6	1.1	-0.3	-1.0	-0.6
Indifference point function log k	3.9	5.5	14.2	-3.8	3.3	-2.8	2.9	2.8	1.6	1.1	-0.3	-1.0	-0.6
Patch foraging total patch changes 0 sec	0.0	0.1	0.1	-0.2	0.2	-0.4	0.2	0.4	0.1	0.2	-0.2	-0.2	-0.4
Patch foraging total patch changes 12 sec	3.2	4.1	8.2	2.9	-2.7	2.4	-2.5	-2.2	-1.8	-1.5	-0.6	1.5	0.8
Patch foraging total patch changes 18 sec	0.5	0.7	1.3	1.0	-1.0	0.7	-1.0	-1.1	-0.7	-0.8	0.3	0.7	0.4
Patch foraging total patch changes 24 sec	0.8	1.0	3.4	1.8	-1.5	1.0	-1.2	-0.8	-0.8	-0.2	-0.6	0.2	-0.2
Patch foraging total patch changes 6 sec	0.9	1.4	2.3	1.5	-1.4	1.2	-1.4	-1.2	-1.4	-1.0	-0.8	1.0	0.5
Patch foraging time to switch 0 sec	3.4	5.3	8.5	1.6	-2.4	2.3	-2.6	-2.9	-2.3	-2.5	0.3	2.7	2.2
Patch foraging water rate 0 sec	5.5	8.8	12.0	-2.6	3.3	-3.4	3.5	3.5	3.0	3.0	0.6	-3.0	-2.7
Patch foraging water rate 12 sec	8.7	13.4	21.4	-3.9	4.3	-4.1	4.3	4.6	3.4	3.4	-0.4	-3.4	-2.9
Patch foraging water rate 18 sec	2.5	3.4	5.6	-2.2	2.3	-2.2	2.2	2.4	1.3	1.4	-0.6	-1.5	-1.3
Patch foraging water rate 24 sec	4.5	6.2	9.5	-2.7	3.0	-2.9	3.0	3.1	2.2	2.3	-0.0	-2.3	-1.9
Patch foraging water rate 6 sec	4.1	5.9	10.7	-2.4	2.9	-2.8	2.9	3.3	2.0	2.3	-0.8	-2.3	-1.6
Seeking ratio, delayed vs. immediate footshock	0.4	0.5	1.4	-0.2	-0.3	0.7	-0.6	-0.7	-0.5	-0.9	-0.3	0.9	1.2
Distance traveled before self-admin	0.3	0.4	0.7	0.7	-0.8	0.7	-0.7	-0.8	-0.3	-0.3	0.7	0.3	0.3
Distance traveled after self-admin	0.1	0.1	0.3	0.5	-0.4	0.4	-0.3	-0.4	0.1	0.1	0.6	0.1	0.1
Extensor digitorum longus weight	5.1	20.2	35.5	6.0	-5.8	5.1	-5.2	-4.5	-4.6	-3.5	-2.1	3.3	3.2
Bone: elastic displacement	2.1	2.4	4.8	-1.0	1.6	-1.7	1.8	2.2	1.2	1.7	-1.0	-1.6	-1.3
Bone: elastic work	0.5	0.6	3.4	1.1	-0.6	0.3	-0.3	0.4	-0.6	0.1	-1.8	-0.4	-0.1
Bone: endosteal estimation	0.4	1.0	2.0	-1.4	0.5	-0.6	-0.0	-0.6	-0.6	-1.2	1.3	1.0	1.4
Bone: endosteal perimeter	0.6	1.2	5.2	-1.5	0.7	-0.9	0.1	-0.6	-0.2	-0.8	2.3	1.0	1.2
Epididymis fat weight	1.1	2.5	6.5	-2.6	2.2	-2.1	1.7	1.1	1.3	0.6	1.7	-0.3	-0.4
Delta time in closed arm before/after self-admin	0.6	0.5	4.3	0.2	-0.2	0.1	-0.1	0.4	-0.8	-0.2	-2.1	0.2	0.2
Delta time in open arm before/after self-admin	0.4	0.4	2.3	0.1	0.1	-0.2	0.2	-0.1	0.9	0.5	1.5	-0.4	-0.8
Diff in mean of infusions in LGA sessions	0.2	0.2	0.7	0.9	-0.3	0.1	-0.1	0.0	0.1	0.4	-0.0	-0.4	-0.7
Delay discount exponential model param	0.4	0.4	1.3	0.3	0.3	-0.7	0.5	0.5	0.5	0.9	0.5	-0.7	-1.1
Extinction: sum of active levers before priming	4.6	4.6	8.0	2.4	-2.5	2.8	-2.5	-2.4	-1.9	-1.9	-0.4	1.9	1.7
Active lever presses in extinction session 6	0.6	0.6	2.8	1.7	-1.0	0.5	-0.5	-0.4	-0.0	0.4	0.5	-0.7	-0.6
Bone: final force	1.9	3.1	5.4	2.3	-2.3	1.8	-2.1	-1.9	-1.8	-1.4	-0.3	1.2	1.4
Bone: final moment	1.7	2.7	4.8	2.2	-2.1	1.7	-2.0	-1.8	-1.7	-1.4	-0.3	1.2	1.3
Food consumed during 24 hour testing period	0.6	0.7	2.2	0.2	0.3	-0.6	0.5	0.5	1.0	1.1	0.8	-1.1	-1.5
Glucose	0.5	0.7	3.4	-1.8	1.0	-0.6	0.5	-0.1	0.0	-0.7	0.9	0.6	1.0
Heart weight	1.1	1.6	4.6	-2.1	1.9	-1.6	1.5	1.3	0.9	0.5	0.2	-0.3	-0.0
Delay discount hyperbolic model param	0.4	0.4	1.2	0.3	0.3	-0.7	0.5	0.5	0.5	0.9	0.6	-0.6	-1.1
Intermittent access intake day 1-15 change	2.1	2.1	2.8	-0.7	1.3	-1.6	1.5	1.2	1.7	1.5	1.6	-1.5	-1.5
Intermittent access intake escalation	1.3	1.3	2.0	-0.6	1.1	-1.2	1.2	0.9	1.4	1.1	1.4	-1.0	-1.1
Intermittent access intake escalation 2	1.3	1.3	2.1	-0.4	0.9	-0.9	1.1	0.9	1.5	1.3	1.3	-1.3	-1.2
Intermitt. access day 1 inactive lever presses	1.5	1.6	3.1	-1.8	1.7	-1.5	1.4	1.0	1.4	0.9	1.3	-0.7	-0.7
Intermitt. access day 15 inactive lever presses	2.2	2.4	4.8	-1.5	1.8	-1.7	1.7	1.0	1.8	1.2	2.2	-1.1	-0.9
Intermitt. access escalation Index	0.8	0.7	3.0	-1.7	1.2	-0.9	0.7	0.5	0.2	-0.3	-0.3	0.4	0.5
Intermittent access day 1 total infusions	1.4	1.6	5.7	-2.4	1.6	-1.5	0.9	-0.0	0.3	-0.4	1.8	0.8	0.6
Intermittent access day 15 total infusions	4.5	5.0	8.7	-2.9	2.9	-3.0	2.4	1.5	2.1	1.4	2.9	-0.9	-1.1
Intermittent access terminal intake (last 3 days)	3.0	3.3	8.7	-2.3	2.3	-2.4	1.8	0.8	1.5	0.9	3.0	-0.5	-0.6
Intermittent access total infusions	1.6	1.8	6.0	-2.0	1.7	-1.7	1.1	0.2	0.9	0.2	2.5	0.2	-0.1
Intermittent access day 1 locomotion	0.9	0.9	3.2	-1.8	1.1	-1.0	0.4	-0.2	-0.3	-0.8	0.6	1.1	1.0
Intermittent access day 15 total locomotion	2.6	2.8	5.8	-2.1	2.2	-2.2	1.7	0.9	1.6	0.9	2.4	-0.5	-0.7
Intermittent access total locomotion	2.1	2.3	7.4	-2.5	2.0	-1.9	1.2	0.1	0.9	-0.1	2.7	0.5	0.3
Intermittent access standard deviation	1.7	1.8	2.6	-1.1	1.5	-1.6	1.5	1.2	1.5	1.4	1.4	-1.1	-1.2
Left kidney weight	0.5	1.3	2.3	-1.5	1.5	-1.3	1.3	0.8	1.3	0.5	1.5	-0.6	-0.5
Right kidney weight	0.5	1.4	3.4	-0.6	1.0	-1.4	1.2	0.7	1.4	1.0	1.8	-1.3	-1.0
Cocaine induced anxiety	0.1	0.1	0.7	-0.1	0.2	-0.2	0.3	0.1	0.4	0.3	0.8	-0.4	-0.2
Post-drug Anxiety	0.2	0.3	1.1	1.0	-0.7	0.4	-0.4	-0.3	-0.1	0.1	0.6	-0.6	-0.1
Baseline Anxiety	0.9	1.0	3.3	1.8	-1.4	1.0	-1.1	-0.6	-0.9	-0.4	-1.1	0.1	0.1
Tail length	0.3	1.0	2.2	1.4	-0.4	0.0	0.2	0.9	0.3	1.2	-1.5	-1.2	-1.5
Length with tail	0.6	2.2	9.7	3.1	-2.1	1.1	-1.4	-0.7	-1.0	0.1	-1.6	-0.5	-0.6
Length without tail	1.0	2.2	7.7	2.8	-2.1	1.1	-1.8	-1.3	-1.5	-0.6	-0.9	0.1	0.4
Times rat made contact with spout	0.6	0.7	1.7	0.7	-0.9	1.3	-0.9	-0.6	-0.8	-0.7	-1.0	0.9	0.4
Lifetime Intake	1.1	1.2	3.6	-1.8	1.5	-1.4	0.9	0.1	0.5	-0.1	1.9	0.5	0.2
Liver weight, left	0.0	0.0	0.1	-0.4	0.2	-0.1	0.2	0.1	0.0	-0.1	0.1	-0.0	-0.0
Liver weight, right	0.1	0.2	0.7	-0.3	0.2	-0.6	0.2	0.4	-0.4	-0.1	-0.8	-0.0	-0.2
Locomotor activity	2.0	3.3	6.1	-1.6	2.0	-2.1	2.1	2.5	1.4	1.7	-0.9	-1.7	-1.5
Locomotor testing distance	2.7	4.5	9.0	-1.9	2.4	-2.4	2.5	3.0	1.5	1.9	-1.5	-1.9	-1.7
Locomotor testing rearing	1.7	2.6	4.9	-1.7	1.9	-1.9	1.8	2.2	1.1	1.4	-1.0	-1.1	-1.3
Locomotion in novel chamber	3.7	4.6	7.2	-2.6	2.6	-2.7	2.4	1.6	2.2	1.5	2.5	-1.3	-1.2
Locomotion in novel chamber post-restriction	1.9	2.2	3.8	-1.9	2.0	-1.9	1.7	1.3	1.5	1.1	1.3	-0.9	-0.8
Fecal boli incidents, locomotor time 1	0.4	0.5	3.7	0.3	0.0	-0.2	0.1	-0.5	0.6	0.2	1.9	-0.3	-0.2
Change in fecal boli incidents, locomotor task	0.8	0.8	3.2	-0.2	-0.4	0.6	-0.6	-0.1	-1.2	-0.8	-1.8	0.8	0.8
Time >=10cm from walls, locomotor time 1	0.8	0.8	3.5	-0.9	0.2	-0.3	-0.2	-1.0	-0.3	-0.7	1.9	1.0	0.8
Bouts of movement, locomotor time 1	0.4	0.5	1.5	1.0	-1.0	1.2	-0.8	-0.7	0.1	-0.1	-0.1	0.0	0.4
Total resting periods, locomotor time 1	0.4	0.4	1.2	0.9	-0.9	1.1	-0.8	-0.8	0.1	-0.1	0.3	0.1	0.4
Rest time, locomotor task time 1	1.5	1.7	2.6	-1.2	1.5	-1.6	1.5	1.4	1.3	1.3	0.7	-1.3	-1.1
Distance moved, locomotor task time 1	0.7	0.8	1.5	0.4	-0.7	0.8	-1.0	-1.1	-1.0	-1.2	-0.2	1.2	0.8
Vertical activity count, locomotor time 1	0.6	0.6	1.4	-1.1	1.2	-1.0	1.0	0.8	0.7	0.5	0.3	-0.4	-0.4
Time >=10cm from walls, locomotor time 2	0.2	0.2	1.2	-0.2	-0.1	0.4	-0.2	-0.5	0.2	-0.1	1.1	0.3	0.1
Bouts of movement, locomotor time 2	0.3	0.4	1.1	0.6	-0.7	1.1	-0.7	-0.6	-0.2	-0.5	-0.2	0.2	0.5
Total resting periods, locomotor time 2	0.3	0.3	0.9	0.4	-0.6	0.9	-0.6	-0.6	-0.1	-0.6	-0.0	0.2	0.6
Rest time, locomotor task time 2	1.2	1.3	3.7	-1.9	1.6	-1.4	1.4	1.0	1.0	0.6	0.7	-0.7	-0.2
Distance moved, locomotor task time 2	0.5	0.5	1.7	1.3	-1.0	1.0	-0.8	-0.6	-0.5	-0.3	-0.5	0.3	-0.1
Vertical activity count, locomotor time 2	0.8	0.9	1.9	-0.0	0.6	-0.8	0.9	1.4	0.6	1.1	-1.0	-1.1	-1.3
Light reinforcement 1	0.3	0.5	1.0	-0.5	0.7	-0.5	0.7	0.8	0.8	0.7	-0.1	-0.6	-1.0
Light reinforcement 2	1.4	1.9	4.2	-1.1	1.4	-1.6	1.4	0.8	1.6	1.2	2.0	-1.1	-1.1
Bone: marrow area	0.5	1.0	2.3	-1.5	0.5	-0.6	-0.0	-0.6	-0.7	-1.2	1.3	1.1	1.5
Bone: maximum diameter	0.2	0.3	2.2	0.5	-0.2	-0.4	-0.1	-0.4	0.1	0.1	1.5	-0.5	0.1
Bone: maximum force	3.6	6.3	9.4	2.6	-2.9	2.5	-2.9	-3.1	-2.6	-2.5	0.2	2.2	2.3
Bone: maximum moment	3.2	5.5	8.1	2.4	-2.7	2.3	-2.7	-2.8	-2.5	-2.3	0.2	2.1	2.1
Mean time between licks in bursts	0.6	0.8	4.8	0.8	-0.7	0.6	-0.6	0.2	-1.0	-0.3	-2.2	0.2	0.1
Mean num. licks in bursts	0.1	0.1	0.3	-0.5	0.3	-0.0	0.2	0.4	0.1	-0.0	-0.6	0.3	-0.1
Cd content in liver	2.5	2.8	3.8	-1.2	1.7	-2.0	1.7	1.3	2.0	1.7	1.7	-1.6	-1.7
Co content in liver	2.3	2.7	5.0	-1.4	1.7	-1.2	1.9	2.2	1.7	1.7	-1.0	-1.6	-1.7
Cu content in liver	0.5	0.6	1.5	0.7	-0.8	1.2	-0.8	-0.9	-0.5	-0.8	-0.1	1.0	0.4
Fe content in liver	0.0	0.0	0.1	0.4	-0.2	-0.2	-0.1	-0.1	-0.1	0.1	0.2	-0.2	-0.1
K content in liver	3.4	3.4	4.4	1.5	-1.9	1.9	-2.0	-2.0	-2.1	-2.0	-0.6	2.0	1.9
Mg content in liver	2.6	2.7	4.7	0.4	-1.2	1.7	-1.6	-1.8	-1.7	-2.1	-0.1	2.2	2.2
Mn content in liver	1.3	1.4	3.8	1.9	-1.7	1.2	-1.5	-1.5	-0.9	-0.6	0.4	0.8	0.3
Na content in liver	0.3	0.3	1.3	1.1	-0.8	0.3	-0.5	-0.4	-0.3	0.0	0.2	0.0	-0.4
Rb content in liver	0.3	0.3	1.8	-1.3	0.7	-0.2	0.3	0.1	0.1	-0.4	0.3	0.6	0.4
Se content in liver	0.3	0.4	3.2	0.2	-0.1	-0.2	-0.2	-0.7	0.2	0.0	1.8	0.2	0.1
Sr content in liver	0.7	0.6	2.9	1.7	-1.1	0.7	-0.6	-0.3	-0.0	0.5	-0.3	-0.7	-0.7
Zn content in liver	1.2	1.3	2.6	1.2	-1.3	1.6	-1.3	-1.3	-0.9	-1.0	-0.3	0.9	0.9
Bone: minimum diameter	0.7	1.4	3.3	-1.1	0.1	0.4	-0.5	-1.1	-0.8	-1.6	1.2	1.7	1.8
Time in familiar zone, hab. session 1	0.2	0.1	0.6	-0.4	0.1	-0.1	-0.1	-0.2	-0.3	-0.4	0.3	0.8	0.5
Time in novel zone, hab. session 1	0.8	0.8	1.3	-0.5	0.7	-0.9	0.8	1.2	0.6	0.9	-0.8	-1.1	-1.0
Total zone transitions, hab. session 1	0.8	1.1	1.8	1.2	-1.2	1.3	-1.2	-1.1	-0.9	-0.9	-0.2	1.1	0.8
Total locomotion distance, hab. session 1	0.1	0.2	0.5	-0.7	0.2	-0.0	0.0	-0.3	-0.2	-0.7	0.3	0.7	0.6
Locomotion velocity, hab. session 1	0.2	0.3	0.7	-0.2	-0.2	0.4	-0.3	-0.6	-0.4	-0.8	0.1	0.7	0.6
Time in familiar zone, hab. session 2	0.4	0.4	2.2	-0.1	0.3	-0.6	0.4	0.9	-0.2	0.4	-1.5	-0.5	-0.4
Time in novel zone, hab. session 2	0.5	0.5	1.0	0.2	-0.5	1.0	-0.7	-1.0	-0.2	-0.7	0.7	0.9	0.9
Total zone transitions, hab. session 2	4.1	5.3	7.4	1.3	-2.3	2.5	-2.6	-2.5	-2.5	-2.6	-0.8	2.7	2.4
Total locomotion distance, hab. session 2	1.3	1.7	3.7	-0.2	-0.8	1.1	-1.2	-1.3	-1.6	-1.9	-0.5	1.7	1.7
Locomotion velocity, hab. session 2	1.0	1.4	3.2	-0.4	-0.6	0.8	-1.0	-1.3	-1.3	-1.8	-0.0	1.6	1.6
Novel to familiar place preference ratio	1.0	1.0	2.1	1.1	-1.1	1.2	-1.1	-1.4	-0.3	-0.6	1.1	0.7	0.7
Novelty place preference	0.6	0.6	1.4	0.7	-0.8	0.9	-0.8	-1.1	-0.1	-0.4	1.2	0.6	0.5
Time in novel zone, NPP test	0.4	0.4	1.0	0.6	-0.7	0.8	-0.7	-1.0	-0.1	-0.3	1.0	0.5	0.5
Total zone transitions, NPP test	2.5	3.6	5.0	1.9	-2.2	2.2	-2.2	-2.1	-2.0	-1.8	-0.6	2.0	1.4
Total locomotion distance, NPP test	0.7	1.0	1.9	0.2	-0.7	1.0	-0.9	-1.0	-1.1	-1.3	-0.4	1.4	1.3
Locomotion velocity, NPP test	0.7	0.9	1.8	0.3	-0.7	1.1	-0.9	-1.0	-1.0	-1.3	-0.2	1.3	1.2
Intraocular pressure	2.4	3.3	4.9	-1.2	1.7	-1.9	1.9	1.5	2.2	2.0	2.1	-1.7	-1.9
Delta distance traveled before/after self-admin	0.1	0.1	0.4	-0.0	0.2	-0.4	0.3	0.5	0.1	0.3	-0.7	-0.3	-0.2
Delta ambulatory time before/after self-admin	0.1	0.2	1.0	0.0	0.1	-0.2	0.2	0.5	-0.0	0.3	-1.0	-0.2	-0.1
Parametrial fat weight	0.7	1.4	6.3	-2.5	1.4	-0.7	0.7	-0.0	0.3	-0.7	1.5	0.9	0.9
Pavlov. Cond. lever latency	0.5	0.6	1.2	-0.5	0.8	-0.8	0.8	0.9	0.9	0.9	-0.0	-0.6	-1.1
Pavlov. Cond. magazine entry latency	1.0	1.3	2.5	0.3	-0.9	1.3	-1.2	-1.4	-0.9	-1.4	0.2	1.3	1.6
Pavlov. Cond. change in total contacts	0.4	0.5	1.2	0.1	-0.4	0.8	-0.5	-1.0	-0.1	-0.6	1.1	0.5	0.9
Pavlov. Cond. index score	0.2	0.2	0.5	0.3	-0.4	0.6	-0.5	-0.6	-0.2	-0.4	0.3	0.2	0.7
Pavlov. Cond. latency score	0.2	0.3	0.7	0.1	-0.4	0.6	-0.5	-0.6	-0.4	-0.6	0.2	0.4	0.9
Pavlov. Cond. lever contacts	0.1	0.2	0.6	0.0	-0.3	0.4	-0.3	-0.4	-0.5	-0.5	-0.1	0.3	0.7
Pavlov. Cond. magazine entry number	0.1	0.1	0.4	-0.5	0.4	-0.4	0.3	0.5	-0.3	-0.1	-0.6	0.2	-0.1
Pavlov. Cond. intertrial magazine entries	0.8	1.0	1.5	-0.4	1.0	-0.9	1.1	0.8	1.2	1.1	1.0	-1.0	-1.0
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	0.8	0.5	-0.7	0.9	-0.8	-0.9	-0.4	-0.6	0.2	0.4	0.9
Pavlov. Cond. response bias	0.1	0.1	0.2	0.3	-0.3	0.4	-0.2	-0.4	0.1	-0.1	0.4	-0.1	0.4
Pavlov. Cond. lever latency	0.3	0.4	0.9	-0.9	0.8	-0.4	0.8	0.9	0.5	0.4	-0.8	-0.4	-0.3
Pavlov. Cond. magazine entry latency	3.2	3.6	5.8	2.4	-2.4	2.3	-2.3	-2.2	-1.7	-1.6	-0.5	1.5	1.3
Pavlov. Cond. change in total contacts	1.7	2.3	4.8	1.9	-1.8	1.7	-1.7	-2.2	-0.7	-1.0	1.5	1.0	1.0
Pavlov. Cond. index score	1.9	2.4	4.4	2.1	-1.9	1.7	-1.9	-2.1	-1.2	-1.2	0.6	1.2	1.0
Pavlov. Cond. latency score	1.7	2.1	3.6	1.9	-1.8	1.5	-1.7	-1.9	-1.1	-1.1	0.6	1.2	1.0
Pavlov. Cond. lever contacts	0.2	0.2	0.9	1.0	-0.5	-0.0	-0.4	-0.4	0.0	0.3	0.7	-0.3	-0.5
Pavlov. Cond. magazine entry number	4.6	5.6	10.3	-3.2	3.1	-2.9	2.9	2.8	1.9	1.8	0.3	-1.6	-1.4
Pavlov. Cond. intertrial magazine entries	0.8	1.1	2.0	-1.4	1.4	-1.4	1.2	1.0	0.9	0.8	0.7	-0.7	-0.5
Pavlov. Cond. lever-magazine prob. diff.	2.3	2.9	5.1	2.3	-2.1	1.9	-2.0	-2.2	-1.3	-1.3	0.4	1.3	1.1
Pavlov. Cond. response bias	0.9	1.2	3.3	1.8	-1.5	1.1	-1.4	-1.4	-0.7	-0.6	0.5	0.5	0.2
Time in closed arm before self-admin	0.2	0.2	1.2	0.0	-0.2	0.1	-0.3	-0.5	0.0	-0.2	1.1	0.2	0.1
Time in closed arm after self-admin	0.2	0.2	0.5	-0.1	-0.1	0.2	-0.2	-0.1	-0.6	-0.4	-0.7	0.4	0.6
Time in open arm before self-admin	0.6	0.6	4.4	-0.6	0.5	-0.0	0.4	0.9	-0.2	-0.2	-2.1	0.1	0.2
Time in open arm after self-admin	0.6	0.6	1.1	-0.5	0.7	-0.7	0.8	0.9	0.9	0.9	-0.2	-0.9	-1.1
Bone: periosteal estimation	0.2	0.5	1.8	-0.0	-0.2	-0.2	-0.3	-0.8	-0.5	-0.8	1.3	0.5	0.9
Bone: periosteal perimeter	0.3	0.4	1.0	0.4	-0.5	0.2	-0.6	-0.9	-0.6	-0.6	1.0	0.5	0.8
Bone: post-yield work	6.2	8.4	14.8	0.6	-2.1	2.5	-2.8	-3.8	-2.6	-3.6	2.1	3.7	3.5
Progressive ratio test 1 active lever presses	1.7	1.8	3.0	-1.6	1.7	-1.6	1.5	1.0	1.3	1.0	1.4	-0.6	-0.9
Progressive ratio test 1 breakpoint	1.8	1.8	3.0	-1.5	1.7	-1.7	1.5	1.1	1.4	1.1	1.3	-0.8	-1.1
Progressive ratio test 1 inactive lever presses	0.4	0.5	1.2	-1.1	1.0	-0.8	0.8	0.6	0.7	0.5	0.3	-0.1	-0.4
Progressive ratio test 2 active lever presses	2.7	2.9	6.1	-1.9	2.2	-2.1	1.8	1.1	1.7	1.2	2.5	-0.8	-1.1
Progressive ratio test 2 breakpoint	4.0	4.5	7.1	-2.2	2.7	-2.6	2.4	1.7	2.2	1.7	2.3	-1.3	-1.6
Progressive ratio test 2 inactive lever presses	4.8	5.5	10.0	-3.2	3.1	-2.8	2.5	1.5	2.4	1.4	3.1	-0.9	-1.1
Incentive Sensitization - Responses	0.3	0.3	2.0	-0.3	0.6	-0.6	0.4	-0.0	0.5	0.2	1.4	-0.1	-0.4
Incentive Sensitization - Breakpoint	0.5	0.5	2.4	-0.5	0.8	-0.8	0.6	0.2	0.7	0.4	1.5	-0.2	-0.5
Sum of active levers in priming session hrs 5-6	1.2	1.1	2.8	1.4	-0.3	-0.1	0.2	0.1	1.0	1.3	1.7	-1.4	-1.3
Progressive ratio	4.8	5.5	8.1	1.5	-2.4	2.6	-2.7	-2.8	-2.4	-2.6	-0.1	2.4	2.6
Food seeking constrained by brief footshock	0.2	0.3	1.7	0.6	-0.4	0.5	-0.3	0.1	-0.6	-0.1	-1.3	0.0	0.1
Seeking ratio, punishment vs. effort	3.0	3.7	6.9	-1.4	2.0	-2.0	2.2	2.6	1.7	2.0	-0.9	-1.9	-1.9
Retroperitoneal fat weight	2.2	7.3	18.9	-4.4	3.8	-3.4	3.1	2.1	2.3	1.2	2.4	-0.6	-0.9
Reaction time number correct	0.1	0.2	0.6	0.8	-0.3	-0.2	0.0	0.3	0.0	0.4	-0.6	-0.7	-0.4
Reaction time mean minus median	1.8	2.4	4.5	2.1	-2.0	1.6	-1.9	-2.0	-1.1	-1.0	0.8	0.7	1.4
Reaction time mean minus median AUC	0.6	0.8	2.5	1.6	-1.2	0.9	-1.0	-1.0	-0.4	-0.2	0.5	-0.1	0.6
Reaction time num false alarms	0.3	0.4	2.0	-0.4	0.6	-0.4	0.6	1.0	-0.1	0.2	-1.4	-0.4	-0.2
Reaction time num false alarms AUC	0.3	0.3	2.7	0.3	-0.1	0.3	0.0	0.5	-0.5	-0.1	-1.7	-0.1	0.1
Reaction time trials correct on left	0.1	0.2	0.6	0.8	-0.3	-0.2	0.0	0.3	0.0	0.4	-0.6	-0.7	-0.4
Reaction time trials on left	0.2	0.2	0.8	0.9	-0.3	-0.1	0.0	0.3	0.0	0.4	-0.6	-0.8	-0.5
Reaction time mean	0.2	0.2	1.4	0.1	-0.1	0.2	-0.1	-0.5	0.5	0.1	1.2	-0.4	0.2
Reaction time mean AUC	0.2	0.3	1.8	0.0	-0.1	0.4	-0.2	-0.6	0.4	-0.1	1.3	-0.2	0.5
Median of all reaction times	0.2	0.2	1.3	-0.4	0.2	0.0	0.2	-0.2	0.6	0.1	1.2	-0.4	0.1
Reaction time omissions	0.7	1.0	2.1	1.5	-1.3	1.4	-1.1	-1.1	-0.7	-0.7	-0.1	0.3	0.7
Reaction time false alarm rate	0.1	0.2	1.2	-0.4	0.4	-0.1	0.3	0.6	-0.3	-0.1	-1.1	0.0	0.1
Reaction time premature initiation rate	1.4	1.8	6.7	1.7	-1.6	1.2	-1.3	-0.4	-1.4	-0.6	-2.6	0.2	0.3
Reaction time premature initiations	1.6	2.2	7.6	2.4	-1.9	1.3	-1.3	-0.3	-1.3	-0.3	-2.8	-0.2	0.0
Std. dev. reaction times	0.4	0.6	1.1	1.0	-0.9	0.8	-0.9	-1.1	-0.2	-0.3	0.9	-0.0	0.7
Reaction time trials completed	0.2	0.2	0.8	0.9	-0.3	-0.1	0.0	0.3	0.0	0.4	-0.6	-0.8	-0.5
Reaction time trials AUC	0.1	0.2	0.5	0.7	-0.2	-0.2	0.1	0.4	-0.0	0.4	-0.7	-0.7	-0.4
Run reversals in cocaine runway, females	3.3	3.2	4.8	0.6	-1.4	1.7	-1.7	-1.5	-2.2	-2.1	-1.9	2.0	2.1
Run reversals in cocaine runway, males	2.0	1.9	2.9	-0.4	1.2	-1.5	1.5	1.7	1.3	1.7	-0.1	-1.7	-1.6
Latency to leave start box in cocaine runway	0.5	0.6	1.3	-0.0	-0.4	0.5	-0.7	-1.0	-0.8	-1.0	0.4	1.1	0.9
Latency to leave start box in cocaine runway, F	0.4	0.4	0.9	0.0	-0.4	0.7	-0.6	-0.8	-0.4	-0.9	0.4	0.9	0.8
Latency to leave start box in cocaine runway, M	0.1	0.1	0.3	0.1	-0.1	-0.2	-0.2	-0.2	-0.5	-0.2	0.1	0.3	0.2
Std. dev. time between licks in bursts	0.4	0.5	3.0	-0.3	0.3	-0.4	0.5	1.1	-0.2	0.3	-1.7	-0.3	-0.2
Total sessions with >9 infusions	0.4	0.4	1.7	-1.3	0.8	-0.9	0.4	0.1	-0.2	-0.3	0.3	0.6	0.4
Short access day 1 total inactive lever presses	1.3	1.4	3.9	-2.0	1.8	-1.5	1.4	1.0	1.0	0.5	0.8	-0.4	-0.1
Short access day 10 total inactive lever presses	1.9	2.1	4.3	-2.1	2.0	-1.7	1.8	1.6	1.3	1.0	-0.2	-0.9	-0.6
Short access day 1 total infusions	0.7	0.7	2.6	-1.6	1.0	-0.7	0.4	-0.2	-0.1	-0.7	0.8	1.1	0.9
Short access day 10 total infusions	1.1	1.2	3.2	-0.8	0.1	0.1	-0.6	-1.3	-1.0	-1.5	1.0	1.8	1.4
Short access total infusions	0.5	0.5	1.4	-0.9	0.4	-0.4	-0.1	-0.6	-0.6	-0.9	0.5	1.2	0.9
Short access day 1 locomotion	0.5	0.5	1.6	-1.3	0.9	-1.0	0.4	-0.1	-0.2	-0.5	0.5	0.9	0.7
Short access day 10 total locomotion	0.4	0.5	1.2	-1.1	0.6	-0.5	0.1	-0.4	-0.3	-0.7	0.5	1.0	0.9
Short access total locomotion	0.4	0.4	1.2	-0.9	0.5	-0.4	-0.0	-0.4	-0.5	-0.8	0.2	1.1	0.9
One hour access (0.3 mA shock)	6.6	7.7	12.9	-3.4	3.6	-3.5	3.2	2.3	2.7	2.1	2.7	-1.6	-1.9
Compulsive drug intake	1.5	1.5	6.3	1.6	-1.4	1.4	-1.1	-0.2	-1.0	-0.3	-2.5	0.1	0.1
One hour access (shock baseline)	6.4	7.5	14.8	-3.2	3.4	-3.3	2.9	1.8	2.8	1.9	3.9	-1.4	-1.5
Social response proportion	0.4	0.5	1.1	0.9	-1.0	0.5	-1.0	-0.9	-0.6	-0.4	0.0	0.4	0.3
Social responses	0.1	0.1	0.5	0.7	-0.3	0.0	-0.2	0.1	-0.1	0.3	-0.4	-0.3	-0.6
Social time	0.2	0.2	0.7	0.7	-0.4	0.2	-0.2	0.2	-0.2	0.3	-0.8	-0.5	-0.6
Soleus weight	2.2	6.5	14.3	-3.8	3.5	-3.1	3.1	2.6	2.3	1.5	1.3	-1.3	-0.9
Bone: stiffness	3.2	5.0	8.2	2.2	-2.6	2.4	-2.6	-2.9	-2.1	-2.2	0.6	2.1	1.9
Tibialis anterior weight	4.2	14.5	44.2	6.6	-5.5	3.9	-4.4	-3.5	-3.6	-1.9	-1.9	1.3	1.3
Time to tail flick, vehicle, before self-admin	0.9	1.0	1.8	0.6	-1.0	1.1	-1.0	-1.1	-1.0	-1.0	0.2	0.9	1.3
Time to tail flick, vehicle, after self-admin	2.4	2.6	4.2	1.1	-1.7	1.6	-1.7	-1.4	-2.0	-1.7	-1.5	1.6	1.5
Time to tail flick, test, before self-admin	0.7	0.7	1.7	-0.7	0.1	0.2	-0.3	-0.5	-1.0	-1.2	-0.5	1.2	1.3
Time to tail flick, test, after self-admin	0.0	0.0	0.1	0.0	0.1	-0.1	0.2	0.3	0.2	0.3	-0.1	-0.3	0.0
Delta time to tail flick, vehicle, before/after SA	0.7	0.7	1.3	0.6	-0.9	0.7	-0.9	-0.7	-1.1	-0.9	-1.1	0.8	0.5
Delta time to tail flick, test, before/after SA	1.1	1.0	2.5	0.9	-0.1	-0.2	0.4	0.8	1.1	1.4	0.2	-1.6	-1.5
Tibia length	0.4	1.1	3.5	1.9	-1.1	0.3	-0.7	-1.0	0.2	0.4	1.8	-0.9	-0.6
Ambulatory time before self-admin	0.3	0.3	1.9	0.5	-0.5	0.4	-0.5	-0.8	0.0	-0.1	1.4	0.1	-0.0
Ambulatory time after self-admin	0.2	0.2	1.6	-0.2	0.0	0.0	-0.1	-0.5	0.2	-0.1	1.3	0.4	0.3
Bone: tissue strength	0.1	0.1	0.4	0.2	-0.2	0.3	-0.3	-0.4	-0.1	-0.2	0.6	0.4	0.4
Total heroin consumption	3.4	4.0	8.0	2.8	-2.6	2.7	-2.3	-2.0	-1.7	-1.4	-0.9	1.1	1.2
Bone: trabecular number	1.2	1.8	3.9	1.0	-1.3	1.2	-1.6	-2.0	-1.2	-1.4	1.0	1.6	0.9
Bone: trabecular spacing	0.3	0.4	1.1	-0.6	0.6	-0.3	0.6	0.9	0.3	0.3	-1.0	-0.5	-0.1
Bone: trabecular thickness	0.2	0.2	0.7	-0.6	0.2	0.0	-0.1	-0.5	-0.1	-0.4	0.8	0.8	0.4
Bone: trabecular tissue density	2.8	4.0	6.4	-2.4	2.5	-2.3	2.4	2.0	2.1	1.6	1.4	-1.3	-1.3
Water consumed over 24 hours	0.3	0.4	1.0	1.0	-0.8	0.9	-0.6	-0.3	-0.2	0.1	-0.7	-0.0	-0.4
Number of responses in last shaping day	1.1	1.1	1.9	-1.0	1.3	-1.4	1.3	1.3	1.0	1.1	-0.1	-0.8	-0.9