Hub : Genes

Rnf111

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Rnf111 0.12 0.1 9.4e-04 0.05 0.05 0.05 0.05 3.3e-03 3.6e-03 3.5e-03 3.9e-03
2 PL intron excision ratio chr8_80025016_80060269 0.03 0.03 2.0e-03 0.01 0 0.01 0.01 1.3e-02 8.6e-02 2.3e-02 4.2e-02
3 pVTA intron excision ratio chr8_80060228_80060682 0.05 0.04 1.3e-03 0.04 0.03 0.03 0.03 6.0e-04 9.9e-04 9.9e-04 8.7e-04
4 NAcc intron excision ratio chr8_80025016_80060682 0.02 0.01 2.2e-03 0.01 0.01 0.01 0.01 6.6e-03 3.7e-03 7.4e-03 1.0e-02
5 Adipose gene expression Rnf111 0.03 0.03 4.1e-04 0.02 0.02 0.02 0.02 1.8e-03 2.2e-03 3.7e-03 2.6e-03
6 Brain gene expression Rnf111 0.04 0.03 2.2e-04 0.03 0.04 0.04 0.03 3.7e-04 1.5e-04 2.9e-04 3.9e-04
7 IC intron excision ratio chr8_80060228_80060682 0.07 0.07 5.4e-03 0.02 0.03 0.02 0.02 4.6e-02 2.9e-02 6.8e-02 5.4e-02
8 NAcc isoform ratio XM_039081135.2 0.02 0.03 1.6e-03 0.01 0.01 0.01 0.01 3.4e-03 2.6e-03 1.3e-02 3.5e-03
9 Brain intron excision ratio chr8_80025016_80060682 0.02 0.02 8.8e-03 0.01 0.01 0.01 0.01 2.8e-02 4.2e-02 2.9e-02 5.9e-02
10 pVTA intron excision ratio chr8_80025016_80060682 0.07 0.07 4.0e-04 0.04 0.04 0.04 0.04 2.6e-04 3.4e-04 4.2e-04 3.5e-04
11 Liver intron excision ratio chr8_80025016_80060166 0.02 0.02 9.8e-03 0.01 0 -0 0 5.9e-02 8.4e-02 8.1e-01 1.0e-01
12 Adipose alternative TSS XM_039081136.2 0.02 0.02 5.2e-03 0.01 0.01 0.01 0.01 9.2e-03 1.0e-02 1.0e-02 1.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.60.91.3-1.1-1.10.8-0.90.91.00.90.9-1.1-0.81.1-1.0
Area under the delay curve0.00.00.10.20.20.2-0.00.20.00.10.10.3-0.2-0.40.3
BMI with tail7.024.225.55.15.1-4.74.9-5.0-5.0-4.9-4.85.04.7-4.95.0
BMI without tail2.78.29.03.03.0-2.82.8-2.9-2.9-2.8-2.82.92.8-2.92.9
Body weight4.720.821.94.74.7-4.54.6-4.7-4.6-4.6-4.64.64.3-4.54.4
Weight adjusted by age4.56.98.72.72.7-2.72.6-2.5-2.6-2.6-2.62.62.9-2.42.4
Bone surface0.00.10.20.20.2-0.40.2-0.3-0.2-0.3-0.30.00.40.00.1
Bone volume0.00.00.1-0.2-0.2-0.1-0.0-0.10.0-0.0-0.0-0.20.10.3-0.1
Breakpoint value in progressive ratio session0.91.11.41.11.1-0.91.0-0.9-1.0-1.0-1.01.11.0-1.21.1
Number of licking bursts1.52.53.7-1.9-1.91.4-1.61.51.61.51.5-1.5-1.41.5-1.5
Context. condit. distance diff. score1.01.21.7-1.2-1.21.2-1.11.11.11.11.1-1.0-1.30.9-0.9
Locomotion velocity, session 11.11.22.10.60.6-1.41.1-1.3-1.1-1.2-1.30.71.4-0.60.9
Locomotion distance, session 10.30.40.8-0.8-0.80.3-0.50.40.60.50.4-0.9-0.30.8-0.7
Locomotion velocity, session 20.10.20.40.10.1-0.60.4-0.4-0.4-0.5-0.50.10.6-0.30.4
Locomotion distance, session 20.10.10.50.00.0-0.60.3-0.3-0.3-0.4-0.50.10.7-0.20.3
Locomotion velocity, session 30.10.10.3-0.5-0.5-0.0-0.10.00.20.10.0-0.6-0.10.5-0.2
Locomotion distance, session 32.22.33.0-1.7-1.71.4-1.51.41.51.41.4-1.7-1.41.6-1.4
Stereotopy head waving bouts, day 30.80.91.51.21.2-0.90.9-0.9-1.0-0.9-0.81.00.8-0.90.8
Stereotopy head waving duration, day 31.01.11.71.31.3-1.01.0-1.0-1.1-1.0-0.91.10.9-1.11.0
Locomotion velocity, session 71.92.13.0-1.7-1.71.3-1.41.21.41.41.3-1.6-1.41.5-1.4
Locomotion distance, session 71.72.23.2-1.8-1.81.5-1.51.41.51.51.4-1.3-1.51.3-1.3
Stereotopy head waving bouts, day 71.51.73.21.81.8-1.11.2-1.1-1.3-1.2-1.11.31.1-1.31.3
Stereotopy head waving duration, day 71.21.43.11.81.8-1.01.1-0.9-1.2-1.0-0.91.10.9-1.11.1
Locomotion velocity, session 80.20.30.6-0.1-0.1-0.80.5-0.7-0.5-0.6-0.70.20.7-0.30.4
Locomotion distance, session 80.71.01.8-1.3-1.30.9-1.01.01.00.90.9-1.1-0.90.9-0.9
Degree of sensitization distance0.20.20.3-0.3-0.30.6-0.40.40.40.50.5-0.1-0.60.1-0.3
Degree of sensitization stereotypy0.80.91.81.31.3-0.80.9-0.7-0.9-0.8-0.80.80.8-0.91.0
Conditioned locomotion0.10.20.3-0.4-0.40.4-0.30.60.30.40.4-0.4-0.40.3-0.3
Cocaine response after cond. corrected3.44.14.41.91.9-2.12.1-1.9-2.1-2.1-2.12.02.0-2.02.1
Cocaine response after cond. not corrected2.12.52.91.41.4-1.71.6-1.5-1.6-1.7-1.71.51.6-1.51.6
Cocaine response before conditioning0.91.11.4-1.0-1.00.9-1.11.01.11.01.0-1.0-1.01.1-1.2
Saline control response0.00.00.10.30.30.2-0.00.30.00.10.20.1-0.3-0.0-0.2
Bone: connectivity density1.01.62.0-1.3-1.31.1-1.21.41.31.21.2-1.3-1.11.4-1.3
Bone: cortical apparent density1.21.71.8-1.3-1.31.3-1.31.31.31.31.3-1.3-1.31.3-1.2
Bone: cortical area0.10.20.4-0.6-0.60.2-0.3-0.00.30.20.2-0.5-0.30.5-0.5
Bone: cortical porosity1.01.11.2-1.0-1.01.0-1.11.11.11.11.1-1.0-1.01.1-1.1
Bone: cortical porosity1.51.61.8-1.3-1.31.2-1.31.31.31.31.3-1.2-1.21.3-1.3
Bone: cortical thickness1.83.04.1-2.0-2.01.5-1.71.41.71.61.6-1.8-1.61.8-1.8
Bone: cortical thickness0.80.91.4-1.2-1.20.8-0.90.80.90.80.8-1.1-0.91.1-1.0
Bone: cortical tissue density1.11.51.7-1.3-1.31.3-1.21.21.21.21.3-1.3-1.21.2-1.2
Condit. Reinf. active minus inactive responses0.00.00.1-0.1-0.10.1-0.1-0.00.10.00.0-0.2-0.00.1-0.2
Condit. Reinf. active-inactive response ratio0.50.50.6-0.8-0.80.8-0.70.60.70.70.7-0.7-0.80.6-0.8
Condit. Reinf. active responses0.30.40.50.60.6-0.60.7-0.7-0.7-0.7-0.70.60.7-0.70.5
Condit. Reinf. inactive responses1.11.31.51.21.2-1.21.2-1.1-1.1-1.2-1.21.11.2-1.10.9
Incentive salience index mean0.00.00.1-0.2-0.2-0.10.0-0.2-0.0-0.1-0.1-0.30.10.2-0.3
Condit. Reinf. lever presses0.10.10.3-0.4-0.40.1-0.1-0.10.10.0-0.0-0.5-0.10.4-0.3
Condit. Reinf. active minus inactive responses2.93.85.41.81.8-2.12.0-2.3-2.0-2.1-2.11.52.1-1.61.5
Condit. Reinf. active-inactive response ratio0.91.01.31.11.1-1.01.1-1.1-1.1-1.1-1.00.81.1-0.90.8
Condit. Reinf. active responses1.52.13.71.31.3-1.71.6-1.9-1.5-1.6-1.71.01.7-1.01.0
Condit. Reinf. inactive responses0.10.10.3-0.2-0.2-0.30.1-0.5-0.1-0.2-0.3-0.40.20.4-0.2
Condit. Reinf. lever presses0.71.02.1-1.0-1.00.7-0.90.50.90.80.8-1.4-0.81.4-1.4
Condit. Reinf. lever reinforcers received1.01.42.61.01.0-1.41.3-1.6-1.2-1.3-1.40.71.3-0.70.7
Conditioned reinforcement - actives0.20.41.01.01.0-0.10.4-0.1-0.5-0.3-0.20.90.1-0.90.8
Conditioned reinforcement - inactives0.10.10.2-0.2-0.20.4-0.30.10.30.30.40.0-0.5-0.0-0.0
Conditioned locomotion0.20.20.8-0.0-0.00.7-0.40.90.40.50.60.0-0.5-0.0-0.1
Patch foraging indifference point 0 sec0.20.40.70.50.5-0.80.7-0.8-0.7-0.8-0.80.30.6-0.20.3
Patch foraging indifference point AUC0.10.10.4-0.3-0.3-0.60.3-0.6-0.2-0.4-0.4-0.00.7-0.00.0
Delay disc. indifference point, 0s delay0.20.30.4-0.3-0.30.6-0.60.60.50.60.6-0.4-0.70.4-0.5
Delay disc. indifference point, 16s delay0.10.10.4-0.1-0.10.6-0.40.50.30.50.50.1-0.6-0.20.0
Delay disc. indifference point, 2s delay0.00.00.20.00.00.4-0.20.30.10.20.30.0-0.3-0.10.2
Delay disc. indifference point, 24s delay0.20.20.5-0.4-0.40.6-0.50.70.50.50.5-0.3-0.60.2-0.3
Delay disc. indifference point, 4s delay0.10.10.3-0.2-0.20.5-0.40.60.30.40.5-0.1-0.50.1-0.2
Delay disc. indifference point, 8s delay0.10.10.20.30.3-0.10.2-0.1-0.2-0.2-0.20.40.1-0.40.5
Indifference point function ln k0.20.40.60.80.8-0.60.6-0.3-0.6-0.6-0.50.80.5-0.80.7
Indifference point function log k0.20.40.60.80.8-0.60.6-0.3-0.6-0.6-0.50.80.5-0.80.7
Patch foraging total patch changes 0 sec0.30.50.90.60.6-0.90.8-0.9-0.7-0.8-0.90.40.8-0.30.3
Patch foraging total patch changes 12 sec0.00.10.2-0.2-0.2-0.20.1-0.4-0.0-0.1-0.1-0.30.20.3-0.4
Patch foraging total patch changes 18 sec0.10.20.70.30.3-0.60.5-0.8-0.5-0.5-0.50.30.5-0.20.3
Patch foraging total patch changes 24 sec0.10.20.7-0.1-0.1-0.80.4-0.7-0.3-0.5-0.6-0.10.70.2-0.2
Patch foraging total patch changes 6 sec0.40.71.20.60.6-0.90.9-1.1-0.8-0.9-1.00.60.9-0.60.7
Patch foraging time to switch 0 sec1.22.43.9-1.2-1.22.0-1.61.71.61.71.7-1.2-1.91.2-1.1
Patch foraging water rate 0 sec1.83.95.31.91.9-2.32.0-2.0-2.0-2.1-2.11.72.2-1.81.6
Patch foraging water rate 12 sec3.06.38.32.32.3-2.92.6-2.7-2.6-2.7-2.72.02.9-2.02.1
Patch foraging water rate 18 sec0.30.50.80.70.7-0.90.7-0.4-0.7-0.8-0.80.40.9-0.50.4
Patch foraging water rate 24 sec0.30.50.70.60.6-0.70.7-0.8-0.7-0.8-0.80.50.7-0.50.6
Patch foraging water rate 6 sec1.42.13.01.41.4-1.71.5-1.3-1.5-1.5-1.51.31.6-1.31.2
Seeking ratio, delayed vs. immediate footshock0.50.60.80.70.7-0.80.8-0.9-0.8-0.8-0.90.90.7-0.80.8
Distance traveled before self-admin0.20.30.60.70.70.40.00.4-0.10.10.20.7-0.6-0.80.6
Distance traveled after self-admin1.11.31.81.41.4-0.91.1-0.9-1.1-1.1-1.01.30.8-1.31.3
Extensor digitorum longus weight8.432.933.75.75.7-5.85.8-5.6-5.8-5.8-5.75.75.8-5.75.7
Bone: elastic displacement0.40.40.60.70.7-0.80.6-0.6-0.7-0.6-0.60.60.7-0.70.7
Bone: elastic work0.00.00.1-0.1-0.1-0.20.1-0.2-0.1-0.1-0.1-0.10.20.00.1
Bone: endosteal estimation2.14.75.22.02.0-2.32.2-2.3-2.2-2.2-2.22.12.2-2.02.1
Bone: endosteal perimeter3.26.97.82.42.4-2.82.7-2.8-2.7-2.7-2.72.62.7-2.52.5
Epididymis fat weight0.00.00.00.20.2-0.00.00.1-0.1-0.00.0-0.00.00.00.1
Delta time in closed arm before/after self-admin1.41.32.0-1.2-1.20.9-1.11.41.11.11.1-1.2-0.91.3-1.1
Delta time in open arm before/after self-admin0.20.20.3-0.4-0.40.3-0.40.20.40.40.3-0.5-0.30.5-0.5
Diff in mean of infusions in LGA sessions1.11.41.71.31.3-1.21.2-1.0-1.2-1.1-1.11.21.2-1.21.1
Delay discount exponential model param0.10.10.2-0.3-0.3-0.1-0.1-0.10.10.0-0.0-0.40.10.5-0.4
Extinction: sum of active levers before priming0.40.40.50.70.7-0.60.7-0.6-0.7-0.7-0.70.70.6-0.70.5
Active lever presses in extinction session 60.70.70.91.01.0-0.70.7-0.9-0.7-0.7-0.70.90.7-0.81.0
Bone: final force0.20.30.90.10.1-0.60.6-0.9-0.5-0.6-0.70.20.6-0.20.3
Bone: final moment0.00.10.3-0.3-0.3-0.20.1-0.5-0.1-0.2-0.3-0.20.10.2-0.1
Food consumed during 24 hour testing period0.71.01.31.11.1-0.91.0-0.9-1.0-1.0-0.91.10.8-1.11.0
Glucose0.91.41.81.01.0-1.41.2-1.2-1.2-1.3-1.31.01.3-1.11.2
Heart weight1.21.83.01.61.6-1.01.3-1.1-1.3-1.2-1.11.71.0-1.71.5
Delay discount hyperbolic model param0.00.00.1-0.2-0.2-0.30.1-0.3-0.0-0.1-0.2-0.20.20.3-0.2
Intermittent access intake day 1-15 change0.50.91.3-0.6-0.61.2-1.01.11.01.11.1-0.9-1.00.9-0.9
Intermittent access intake escalation0.30.70.9-0.5-0.50.9-0.80.90.80.90.9-0.8-0.80.9-0.8
Intermittent access intake escalation 20.00.00.10.30.30.2-0.00.2-0.00.10.10.2-0.1-0.10.2
Intermitt. access day 1 inactive lever presses1.14.04.7-1.9-1.91.9-2.02.22.02.02.0-2.1-1.92.1-2.1
Intermitt. access day 15 inactive lever presses0.10.20.60.70.7-0.00.20.1-0.3-0.1-0.10.5-0.1-0.50.4
Intermitt. access escalation Index0.30.51.10.70.7-0.60.6-1.1-0.6-0.6-0.60.80.5-0.90.5
Intermittent access day 1 total infusions0.50.81.1-0.9-0.91.0-0.91.00.90.90.9-0.7-1.00.7-0.7
Intermittent access day 15 total infusions1.21.82.3-1.1-1.11.5-1.41.31.31.41.4-1.3-1.41.3-1.3
Intermittent access terminal intake (last 3 days)0.50.61.1-0.5-0.51.1-0.80.80.80.90.9-0.7-0.80.7-0.6
Intermittent access total infusions0.20.30.5-0.4-0.40.7-0.60.60.60.60.6-0.4-0.60.4-0.4
Intermittent access day 1 locomotion2.32.93.7-1.6-1.61.8-1.71.91.71.71.8-1.7-1.71.7-1.6
Intermittent access day 15 total locomotion1.32.34.9-1.2-1.21.6-1.52.21.51.51.6-1.5-1.31.5-1.4
Intermittent access total locomotion0.10.10.60.20.20.3-0.10.80.10.20.2-0.10.00.1-0.0
Intermittent access standard deviation0.20.30.7-0.4-0.40.7-0.60.90.60.60.7-0.5-0.60.6-0.3
Left kidney weight1.88.310.03.23.2-2.72.9-2.8-2.9-2.8-2.73.12.6-2.93.0
Right kidney weight2.611.613.83.63.6-3.03.4-3.4-3.4-3.3-3.33.73.0-3.63.5
Cocaine induced anxiety0.10.10.2-0.2-0.20.5-0.30.40.30.40.4-0.2-0.40.1-0.1
Post-drug Anxiety2.42.62.9-1.6-1.61.7-1.61.61.61.71.7-1.5-1.71.5-1.5
Baseline Anxiety0.81.01.3-1.1-1.10.8-1.00.81.00.90.9-1.1-0.81.1-1.0
Tail length0.00.00.0-0.0-0.0-0.1-0.0-0.1-0.00.00.0-0.0-0.00.0-0.1
Length with tail0.52.43.01.51.5-1.71.6-1.7-1.6-1.6-1.71.41.4-1.41.3
Length without tail3.611.512.93.33.3-3.53.5-3.6-3.5-3.5-3.63.33.3-3.23.2
Times rat made contact with spout0.40.51.3-0.5-0.50.8-0.71.10.70.80.9-0.3-0.70.4-0.4
Lifetime Intake0.10.20.3-0.5-0.50.5-0.40.30.40.40.4-0.3-0.40.3-0.2
Liver weight, left3.76.17.62.32.3-2.82.5-2.5-2.5-2.6-2.62.32.8-2.22.2
Liver weight, right1.11.82.70.90.9-1.51.5-1.6-1.4-1.5-1.61.21.4-1.21.2
Locomotor activity6.510.211.43.43.4-3.23.2-2.9-3.2-3.1-3.13.33.1-3.33.1
Locomotor testing distance3.86.88.42.92.9-2.62.6-2.3-2.6-2.5-2.42.72.5-2.72.6
Locomotor testing rearing1.73.54.32.12.1-1.81.8-1.8-1.8-1.8-1.81.81.7-1.81.9
Locomotion in novel chamber0.20.30.8-0.4-0.40.5-0.50.50.50.50.6-0.5-0.50.7-0.9
Locomotion in novel chamber post-restriction0.50.91.4-1.0-1.01.2-0.90.80.91.01.0-0.8-1.10.7-0.8
Fecal boli incidents, locomotor time 10.00.10.2-0.1-0.10.4-0.20.10.20.30.3-0.2-0.50.2-0.2
Change in fecal boli incidents, locomotor task0.00.00.1-0.0-0.0-0.30.1-0.1-0.1-0.2-0.20.20.4-0.20.1
Time >=10cm from walls, locomotor time 10.20.20.30.60.6-0.40.4-0.2-0.4-0.4-0.40.50.4-0.40.5
Bouts of movement, locomotor time 10.10.10.20.40.4-0.40.3-0.4-0.3-0.3-0.2-0.00.10.2-0.1
Total resting periods, locomotor time 10.10.10.20.40.4-0.40.3-0.3-0.3-0.3-0.20.00.20.1-0.1
Rest time, locomotor task time 10.00.00.00.00.0-0.20.00.1-0.0-0.0-0.1-0.00.10.1-0.1
Distance moved, locomotor task time 10.10.10.2-0.4-0.40.3-0.30.20.30.30.3-0.3-0.10.2-0.2
Vertical activity count, locomotor time 10.10.20.4-0.3-0.30.6-0.40.50.40.50.5-0.2-0.50.2-0.2
Time >=10cm from walls, locomotor time 20.00.00.1-0.1-0.1-0.20.1-0.2-0.0-0.1-0.1-0.10.30.1-0.0
Bouts of movement, locomotor time 21.21.93.01.71.7-1.21.3-1.1-1.4-1.3-1.21.61.0-1.41.4
Total resting periods, locomotor time 21.22.13.41.81.8-1.21.4-1.1-1.4-1.3-1.31.61.1-1.51.5
Rest time, locomotor task time 20.20.30.5-0.3-0.30.5-0.50.50.50.50.5-0.6-0.70.6-0.5
Distance moved, locomotor task time 20.00.00.2-0.4-0.4-0.1-0.10.00.10.00.0-0.10.30.2-0.1
Vertical activity count, locomotor time 20.30.40.8-0.5-0.50.9-0.70.90.70.70.8-0.3-0.60.3-0.4
Light reinforcement 12.35.56.22.12.1-2.52.5-2.5-2.4-2.5-2.52.32.5-2.32.1
Light reinforcement 20.10.20.4-0.6-0.60.2-0.40.20.40.30.3-0.6-0.30.6-0.5
Bone: marrow area2.14.65.22.02.0-2.32.2-2.2-2.2-2.2-2.22.12.2-2.02.0
Bone: maximum diameter1.93.54.51.51.5-2.12.0-2.1-1.9-2.0-2.01.72.0-1.61.7
Bone: maximum force0.20.30.70.20.2-0.70.6-0.8-0.5-0.6-0.70.40.6-0.30.4
Bone: maximum moment0.00.00.2-0.1-0.1-0.20.2-0.5-0.1-0.2-0.3-0.00.20.10.0
Mean time between licks in bursts0.20.40.7-0.6-0.60.7-0.70.90.70.70.7-0.4-0.70.3-0.6
Mean num. licks in bursts0.71.12.01.41.4-0.91.0-0.7-1.0-0.9-0.91.10.9-1.11.1
Cd content in liver1.31.51.8-1.1-1.11.3-1.21.21.21.31.3-1.1-1.41.1-1.1
Co content in liver1.21.41.7-1.3-1.31.1-1.21.31.21.21.3-1.1-1.21.0-1.1
Cu content in liver0.00.00.1-0.3-0.3-0.10.0-0.00.0-0.0-0.10.10.20.00.0
Fe content in liver0.20.20.40.40.4-0.60.6-0.5-0.6-0.6-0.60.40.5-0.30.3
K content in liver1.81.82.91.21.2-1.51.4-1.1-1.4-1.4-1.41.21.7-1.21.2
Mg content in liver1.61.72.11.21.2-1.41.3-1.2-1.3-1.3-1.31.31.5-1.21.2
Mn content in liver0.00.00.1-0.2-0.20.1-0.20.30.20.10.20.0-0.10.0-0.1
Na content in liver7.78.29.62.52.5-3.13.0-2.9-3.0-3.0-3.12.73.1-2.72.7
Rb content in liver0.60.70.90.90.9-0.90.8-0.7-0.8-0.8-0.80.81.0-0.80.8
Se content in liver0.00.00.1-0.2-0.20.1-0.20.30.10.20.2-0.3-0.10.3-0.3
Sr content in liver0.00.00.1-0.3-0.30.2-0.20.10.20.20.2-0.2-0.20.2-0.2
Zn content in liver0.00.00.20.10.1-0.30.2-0.1-0.2-0.2-0.20.10.4-0.00.1
Bone: minimum diameter0.00.10.2-0.2-0.20.3-0.20.00.20.20.2-0.3-0.40.4-0.4
Time in familiar zone, hab. session 10.00.00.1-0.3-0.3-0.1-0.10.10.10.10.0-0.20.10.3-0.2
Time in novel zone, hab. session 10.00.00.1-0.1-0.10.3-0.20.20.20.20.2-0.1-0.40.0-0.0
Total zone transitions, hab. session 10.60.81.4-1.2-1.20.6-0.80.80.80.70.7-1.0-0.51.0-1.1
Total locomotion distance, hab. session 10.10.10.3-0.5-0.50.2-0.30.30.30.20.2-0.2-0.10.3-0.4
Locomotion velocity, hab. session 10.00.00.0-0.2-0.20.00.00.0-0.0-0.0-0.0-0.00.20.0-0.2
Time in familiar zone, hab. session 20.00.10.1-0.3-0.30.3-0.30.10.30.20.2-0.2-0.20.2-0.1
Time in novel zone, hab. session 20.00.00.1-0.0-0.00.1-0.10.20.10.10.2-0.2-0.20.2-0.2
Total zone transitions, hab. session 20.30.30.70.10.1-0.80.6-0.7-0.6-0.7-0.70.50.8-0.40.5
Total locomotion distance, hab. session 20.70.91.30.70.7-1.01.0-1.0-1.0-1.0-1.01.11.1-1.01.0
Locomotion velocity, hab. session 20.40.50.70.40.4-0.70.7-0.7-0.7-0.7-0.70.80.9-0.80.7
Novel to familiar place preference ratio1.01.11.71.31.3-0.91.0-1.1-1.0-1.0-1.01.00.9-1.01.1
Novelty place preference1.01.11.71.31.3-0.91.1-1.1-1.1-1.0-1.00.90.9-1.01.1
Time in novel zone, NPP test1.31.42.01.41.4-1.01.2-1.2-1.2-1.1-1.11.01.0-1.11.2
Total zone transitions, NPP test0.20.30.80.40.4-0.80.5-0.5-0.5-0.6-0.60.20.9-0.20.2
Total locomotion distance, NPP test0.60.81.30.80.8-1.00.9-0.9-0.9-0.9-0.90.71.1-0.70.7
Locomotion velocity, NPP test0.20.30.70.50.5-0.60.6-0.5-0.6-0.6-0.60.40.8-0.40.3
Intraocular pressure0.00.00.2-0.1-0.10.10.0-0.0-0.0-0.0-0.10.4-0.0-0.40.3
Delta distance traveled before/after self-admin1.11.22.00.80.8-1.31.2-1.4-1.1-1.2-1.30.71.4-0.70.8
Delta ambulatory time before/after self-admin0.40.40.90.40.4-0.80.7-1.0-0.7-0.8-0.80.30.9-0.30.3
Parametrial fat weight1.02.44.0-2.0-2.01.4-1.51.51.51.51.4-1.4-1.51.4-1.3
Pavlov. Cond. lever latency0.10.10.2-0.3-0.30.5-0.40.40.40.40.4-0.1-0.50.2-0.1
Pavlov. Cond. magazine entry latency0.70.91.4-1.1-1.10.8-0.90.80.90.80.8-1.2-0.81.1-1.0
Pavlov. Cond. change in total contacts0.00.00.00.10.10.00.00.1-0.00.00.1-0.1-0.00.1-0.2
Pavlov. Cond. index score0.50.71.1-0.9-0.90.7-0.70.70.70.70.7-1.0-0.61.0-1.0
Pavlov. Cond. latency score0.20.30.6-0.6-0.60.3-0.40.30.40.40.4-0.7-0.30.7-0.7
Pavlov. Cond. lever contacts0.00.00.1-0.2-0.2-0.20.0-0.1-0.0-0.1-0.1-0.20.20.1-0.1
Pavlov. Cond. magazine entry number1.01.21.61.21.2-1.01.1-0.9-1.1-1.0-1.01.31.0-1.21.2
Pavlov. Cond. intertrial magazine entries0.10.10.20.30.3-0.40.3-0.4-0.3-0.4-0.40.30.4-0.40.3
Pavlov. Cond. lever-magazine prob. diff.0.30.30.7-0.7-0.70.4-0.50.40.50.50.5-0.8-0.40.8-0.7
Pavlov. Cond. response bias0.40.50.8-0.8-0.80.5-0.60.60.60.60.6-0.9-0.50.8-0.7
Pavlov. Cond. lever latency0.40.51.10.70.7-0.40.6-0.3-0.6-0.5-0.51.10.4-1.11.1
Pavlov. Cond. magazine entry latency3.64.45.4-2.1-2.12.0-2.12.12.12.02.1-2.1-1.92.2-2.3
Pavlov. Cond. change in total contacts0.40.61.3-0.8-0.80.6-0.70.60.70.70.7-1.0-0.61.0-1.2
Pavlov. Cond. index score1.01.42.1-1.2-1.20.9-1.11.01.11.11.0-1.4-0.91.4-1.5
Pavlov. Cond. latency score0.60.91.4-1.0-1.00.7-0.80.80.90.80.8-1.2-0.71.2-1.2
Pavlov. Cond. lever contacts0.30.41.0-0.7-0.70.3-0.50.30.60.50.4-1.0-0.41.0-1.0
Pavlov. Cond. magazine entry number3.74.65.42.32.3-1.92.1-2.1-2.1-2.1-2.12.31.9-2.32.3
Pavlov. Cond. intertrial magazine entries0.91.41.91.11.1-1.21.2-1.4-1.2-1.2-1.21.21.1-1.21.2
Pavlov. Cond. lever-magazine prob. diff.1.21.62.3-1.3-1.31.0-1.21.11.21.11.1-1.5-1.01.5-1.5
Pavlov. Cond. response bias1.62.13.3-1.5-1.51.2-1.41.21.41.31.3-1.7-1.21.7-1.8
Time in closed arm before self-admin0.10.10.50.30.30.4-0.20.70.20.30.40.1-0.4-0.0-0.0
Time in closed arm after self-admin0.70.71.7-0.5-0.50.9-0.91.30.90.91.0-0.6-0.90.7-0.8
Time in open arm before self-admin0.60.71.40.70.7-0.60.7-1.2-0.7-0.8-0.80.90.7-1.01.0
Time in open arm after self-admin0.30.30.90.50.5-0.50.6-0.9-0.5-0.6-0.60.50.5-0.50.5
Bone: periosteal estimation1.02.12.91.21.2-1.61.5-1.7-1.5-1.6-1.61.31.5-1.21.3
Bone: periosteal perimeter1.72.93.91.41.4-1.81.8-2.0-1.8-1.8-1.81.61.7-1.51.6
Bone: post-yield work0.10.10.10.40.4-0.30.3-0.2-0.3-0.3-0.30.40.3-0.40.3
Progressive ratio test 1 active lever presses0.10.10.2-0.4-0.40.4-0.40.30.40.40.4-0.2-0.40.2-0.1
Progressive ratio test 1 breakpoint0.10.20.2-0.5-0.50.5-0.40.30.40.40.4-0.2-0.40.2-0.2
Progressive ratio test 1 inactive lever presses2.23.24.2-2.1-2.11.7-1.81.61.91.81.7-1.7-1.71.8-1.7
Progressive ratio test 2 active lever presses0.20.20.40.50.5-0.20.4-0.2-0.4-0.3-0.30.60.3-0.60.6
Progressive ratio test 2 breakpoint0.10.20.40.50.5-0.20.3-0.2-0.4-0.3-0.30.50.3-0.50.6
Progressive ratio test 2 inactive lever presses0.10.20.3-0.3-0.30.5-0.50.50.40.50.5-0.4-0.50.4-0.3
Incentive Sensitization - Responses0.20.30.70.80.8-0.20.5-0.3-0.5-0.4-0.40.60.2-0.60.7
Incentive Sensitization - Breakpoint0.10.20.50.70.7-0.10.3-0.2-0.4-0.3-0.20.50.1-0.50.6
Sum of active levers in priming session hrs 5-60.10.10.20.50.5-0.30.3-0.1-0.3-0.3-0.30.30.2-0.50.4
Progressive ratio0.61.01.8-0.5-0.51.3-1.11.21.01.21.3-0.4-1.30.7-0.6
Food seeking constrained by brief footshock0.20.30.50.50.5-0.70.5-0.5-0.5-0.5-0.50.50.6-0.50.5
Seeking ratio, punishment vs. effort3.24.76.71.71.7-2.62.3-2.4-2.2-2.4-2.51.62.6-1.81.7
Retroperitoneal fat weight0.10.30.7-0.8-0.80.4-0.40.50.40.40.3-0.6-0.40.8-0.7
Reaction time number correct1.22.23.01.61.6-1.41.5-1.0-1.5-1.4-1.41.61.5-1.71.7
Reaction time mean minus median0.00.10.4-0.2-0.20.1-0.2-0.30.20.10.1-0.70.10.6-0.6
Reaction time mean minus median AUC0.30.61.4-0.8-0.80.6-0.70.30.70.70.6-1.2-0.41.1-1.1
Reaction time num false alarms0.60.81.4-1.2-1.20.9-0.80.70.90.80.8-0.8-0.90.9-0.9
Reaction time num false alarms AUC0.20.30.7-0.8-0.80.6-0.50.30.50.40.4-0.5-0.50.6-0.6
Reaction time trials correct on left1.22.23.01.61.6-1.41.5-1.0-1.5-1.4-1.41.61.5-1.71.7
Reaction time trials on left1.32.43.21.61.6-1.51.5-1.1-1.5-1.5-1.51.71.5-1.71.8
Reaction time mean2.13.44.7-2.0-2.01.6-1.81.51.81.71.7-2.0-1.42.1-2.2
Reaction time mean AUC1.52.33.2-1.7-1.71.3-1.51.31.51.41.4-1.7-1.21.7-1.8
Median of all reaction times4.25.97.2-2.7-2.72.2-2.42.32.42.32.3-2.5-2.12.6-2.7
Reaction time omissions0.20.30.50.40.4-0.50.5-0.7-0.5-0.5-0.60.40.7-0.40.4
Reaction time false alarm rate1.41.92.7-1.7-1.71.4-1.30.91.31.31.2-1.4-1.31.5-1.5
Reaction time premature initiation rate1.72.42.81.31.3-1.61.6-1.7-1.6-1.6-1.61.51.6-1.51.5
Reaction time premature initiations2.24.04.41.81.8-2.02.0-1.9-2.0-2.0-2.02.02.1-2.12.1
Std. dev. reaction times0.61.11.9-1.1-1.10.9-1.00.61.01.00.9-1.3-0.71.4-1.4
Reaction time trials completed1.32.43.21.61.6-1.51.5-1.1-1.5-1.5-1.51.71.5-1.71.8
Reaction time trials AUC1.12.02.81.51.5-1.31.4-0.9-1.4-1.4-1.41.61.4-1.61.7
Run reversals in cocaine runway, females0.00.00.0-0.2-0.2-0.0-0.10.20.10.10.10.10.00.00.1
Run reversals in cocaine runway, males0.00.00.10.20.2-0.30.2-0.3-0.2-0.2-0.30.00.3-0.10.1
Latency to leave start box in cocaine runway2.52.94.12.02.0-1.21.6-1.7-1.7-1.6-1.51.81.2-1.91.9
Latency to leave start box in cocaine runway, F0.70.91.41.21.2-0.60.9-1.0-0.9-0.9-0.80.90.7-1.00.9
Latency to leave start box in cocaine runway, M6.05.67.02.62.6-1.92.3-2.3-2.3-2.2-2.22.61.9-2.62.7
Std. dev. time between licks in bursts0.30.50.90.50.5-0.90.7-1.0-0.7-0.8-0.80.40.8-0.40.4
Total sessions with >9 infusions0.20.20.5-0.7-0.70.3-0.4-0.10.40.40.3-0.4-0.20.5-0.4
Short access day 1 total inactive lever presses0.60.81.0-1.0-1.01.0-0.90.70.90.90.9-0.6-0.90.8-0.8
Short access day 10 total inactive lever presses0.61.53.1-0.8-0.81.3-1.21.81.21.31.3-1.1-1.31.2-1.2
Short access day 1 total infusions0.10.20.4-0.4-0.40.6-0.40.20.40.50.5-0.1-0.50.20.0
Short access day 10 total infusions1.11.41.8-1.4-1.41.2-1.20.91.21.21.2-1.1-1.01.1-1.0
Short access total infusions0.40.60.9-0.9-0.90.8-0.80.40.80.80.7-0.7-0.60.7-0.6
Short access day 1 locomotion0.10.10.2-0.5-0.50.4-0.30.00.30.30.30.0-0.2-0.00.2
Short access day 10 total locomotion0.30.50.9-0.8-0.80.6-0.70.70.70.60.6-0.9-0.41.0-0.9
Short access total locomotion0.40.50.7-0.8-0.80.7-0.70.40.70.70.7-0.7-0.50.7-0.7
One hour access (0.3 mA shock)0.80.91.51.11.1-0.80.9-0.7-0.9-0.8-0.81.00.9-1.01.2
Compulsive drug intake1.41.62.11.01.0-1.51.3-1.2-1.3-1.4-1.41.21.4-1.31.2
One hour access (shock baseline)0.10.20.4-0.2-0.20.6-0.50.50.50.50.6-0.3-0.60.3-0.1
Social response proportion0.20.20.4-0.1-0.10.6-0.50.50.40.50.6-0.3-0.70.3-0.6
Social responses0.00.00.10.20.2-0.20.1-0.2-0.1-0.2-0.1-0.30.10.2-0.3
Social time0.00.10.30.30.30.4-0.00.10.00.10.10.1-0.5-0.00.1
Soleus weight16.849.551.77.07.0-7.27.1-6.9-7.1-7.1-7.07.07.2-7.07.0
Bone: stiffness0.61.01.40.90.9-0.91.1-1.2-1.0-1.1-1.10.90.9-0.80.8
Tibialis anterior weight13.947.149.86.76.7-6.86.9-7.1-6.9-6.9-6.96.86.9-6.86.9
Time to tail flick, vehicle, before self-admin0.30.30.6-0.5-0.50.4-0.40.30.50.40.4-0.8-0.20.8-0.8
Time to tail flick, vehicle, after self-admin0.91.23.1-0.4-0.41.3-1.11.81.11.31.4-0.6-1.50.5-0.7
Time to tail flick, test, before self-admin2.02.12.6-1.6-1.61.2-1.41.21.41.41.4-1.5-1.21.6-1.6
Time to tail flick, test, after self-admin2.42.55.2-0.9-0.92.3-1.71.71.71.92.0-0.9-2.11.0-1.0
Delta time to tail flick, vehicle, before/after SA0.80.81.7-0.4-0.41.0-0.91.30.91.01.1-0.4-1.30.4-0.5
Delta time to tail flick, test, before/after SA0.20.20.60.80.80.20.2-0.1-0.3-0.1-0.10.6-0.1-0.60.7
Tibia length0.10.10.3-0.3-0.30.3-0.30.50.30.40.4-0.4-0.40.4-0.5
Ambulatory time before self-admin0.10.10.40.20.20.5-0.20.50.20.30.30.3-0.6-0.30.2
Ambulatory time after self-admin0.40.50.60.80.8-0.50.7-0.7-0.7-0.7-0.70.80.5-0.80.8
Bone: tissue strength1.41.51.7-1.2-1.21.3-1.21.11.21.21.2-1.2-1.21.2-1.2
Total heroin consumption1.71.92.81.71.7-1.01.3-1.1-1.3-1.2-1.11.71.1-1.71.6
Bone: trabecular number1.52.43.0-1.7-1.71.4-1.51.51.61.51.5-1.7-1.31.7-1.6
Bone: trabecular spacing0.00.10.10.30.3-0.20.2-0.2-0.2-0.2-0.20.30.2-0.40.2
Bone: trabecular thickness0.50.71.1-1.1-1.10.7-0.80.80.80.80.8-0.7-0.70.8-0.7
Bone: trabecular tissue density4.46.57.52.32.3-2.72.6-2.7-2.6-2.6-2.72.42.7-2.42.5
Water consumed over 24 hours0.30.30.5-0.5-0.50.7-0.60.70.60.60.6-0.4-0.70.5-0.5
Number of responses in last shaping day0.00.10.20.30.30.4-0.20.20.10.30.30.1-0.2-0.00.1