Hub : Genes

Rnf111

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Rnf111 0.12 0.1 9.4e-04 0.05 0.05 0.05 0.05 3.3e-03 3.6e-03 3.4e-03 3.8e-03
2 PL intron excision ratio chr8_80025016_80060269 0.03 0.03 2.0e-03 0.01 0 0.01 0.01 1.3e-02 8.6e-02 2.3e-02 4.1e-02
3 pVTA intron excision ratio chr8_80060228_80060682 0.05 0.04 1.3e-03 0.04 0.03 0.03 0.03 6.0e-04 9.9e-04 4.2e-03 8.7e-04
4 NAcc intron excision ratio chr8_80025016_80060682 0.02 0.01 2.2e-03 0.01 0.01 0.01 0.01 6.6e-03 3.7e-03 7.4e-03 1.1e-02
5 Adipose gene expression Rnf111 0.03 0.03 4.1e-04 0.02 0.02 0.02 0.02 1.8e-03 2.2e-03 3.8e-03 2.8e-03
6 Brain gene expression Rnf111 0.04 0.03 2.2e-04 0.03 0.04 0.04 0.03 3.7e-04 1.5e-04 2.9e-04 3.8e-04
7 IC intron excision ratio chr8_80060228_80060682 0.07 0.07 5.4e-03 0.02 0.03 0.02 0.02 4.6e-02 2.9e-02 6.9e-02 5.6e-02
8 NAcc isoform ratio XM_039081135.2 0.02 0.03 1.6e-03 0.01 0.01 0.01 0.01 3.4e-03 2.6e-03 1.3e-02 3.6e-03
9 Brain intron excision ratio chr8_80025016_80060682 0.02 0.02 8.8e-03 0.01 0.01 0.01 0.01 2.8e-02 4.2e-02 2.9e-02 6.0e-02
10 pVTA intron excision ratio chr8_80025016_80060682 0.07 0.07 4.0e-04 0.04 0.04 0.04 0.04 2.6e-04 3.4e-04 4.2e-04 3.6e-04
11 Liver intron excision ratio chr8_80025016_80060166 0.02 0.02 9.8e-03 0.01 0 -0 0 5.9e-02 8.4e-02 7.8e-01 9.9e-02
12 Adipose alternative TSS XM_039081136.2 0.02 0.02 5.2e-03 0.01 0.01 0.01 0.01 9.2e-03 1.0e-02 1.0e-02 1.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.50.91.31.11.1-0.8-0.9-0.91.00.90.91.10.8-1.11.0
Area under the delay curve0.00.00.1-0.2-0.2-0.2-0.0-0.20.00.10.1-0.30.20.4-0.3
BMI with tail6.924.225.5-5.1-5.14.74.95.0-5.0-4.9-4.8-5.0-4.74.9-5.0
BMI without tail1.58.29.0-3.0-3.02.82.82.9-2.9-2.8-2.8-2.9-2.82.9-2.9
Body weight4.720.821.9-4.7-4.74.54.64.7-4.6-4.6-4.6-4.6-4.34.5-4.4
Weight adjusted by age2.36.98.7-2.7-2.72.72.62.5-2.6-2.6-2.6-2.6-2.92.4-2.4
Bone surface0.00.10.2-0.2-0.20.40.20.3-0.2-0.3-0.3-0.0-0.4-0.0-0.1
Bone volume0.00.00.10.20.20.1-0.00.10.0-0.0-0.00.2-0.1-0.30.1
Breakpoint value in progressive ratio session0.61.11.4-1.1-1.10.91.00.9-1.0-1.0-1.0-1.1-1.01.2-1.1
Number of licking bursts0.82.53.71.91.9-1.4-1.6-1.51.61.51.51.51.4-1.51.5
Context. condit. distance diff. score1.01.21.71.21.2-1.2-1.1-1.11.11.11.11.01.3-0.90.9
Locomotion velocity, session 11.01.22.1-0.6-0.61.41.11.3-1.1-1.2-1.3-0.7-1.40.6-0.9
Locomotion distance, session 10.30.40.80.80.8-0.3-0.5-0.40.60.50.40.90.3-0.80.7
Locomotion velocity, session 20.10.20.4-0.1-0.10.60.40.4-0.4-0.5-0.5-0.1-0.60.3-0.4
Locomotion distance, session 20.10.10.5-0.0-0.00.60.30.3-0.3-0.4-0.5-0.1-0.70.2-0.3
Locomotion velocity, session 30.10.10.30.50.50.0-0.1-0.00.20.10.00.60.1-0.50.2
Locomotion distance, session 32.02.33.01.71.7-1.4-1.5-1.41.51.41.41.71.4-1.61.4
Stereotopy head waving bouts, day 30.80.91.5-1.2-1.20.90.90.9-1.0-0.9-0.8-1.0-0.80.9-0.8
Stereotopy head waving duration, day 30.91.11.7-1.3-1.31.01.01.0-1.1-1.0-0.9-1.1-0.91.1-1.0
Locomotion velocity, session 71.92.13.01.71.7-1.3-1.4-1.21.41.41.31.61.4-1.51.4
Locomotion distance, session 71.72.23.21.81.8-1.5-1.5-1.41.51.51.41.31.5-1.31.3
Stereotopy head waving bouts, day 71.51.73.2-1.8-1.81.11.21.1-1.3-1.2-1.1-1.3-1.11.3-1.3
Stereotopy head waving duration, day 71.11.43.1-1.8-1.81.01.10.9-1.2-1.0-0.9-1.1-0.91.1-1.1
Locomotion velocity, session 80.20.30.60.10.10.80.50.7-0.5-0.6-0.7-0.2-0.70.3-0.4
Locomotion distance, session 80.71.01.81.31.3-0.9-1.0-1.01.00.90.91.10.9-0.90.9
Degree of sensitization distance0.10.20.30.30.3-0.6-0.4-0.40.40.50.50.10.6-0.10.3
Degree of sensitization stereotypy0.80.91.8-1.3-1.30.80.90.7-0.9-0.8-0.8-0.8-0.80.9-1.0
Conditioned locomotion0.10.20.30.40.4-0.4-0.3-0.60.30.40.40.40.4-0.30.3
Cocaine response after cond. corrected2.74.14.4-1.9-1.92.12.11.9-2.1-2.1-2.1-2.0-2.02.0-2.1
Cocaine response after cond. not corrected1.72.52.9-1.4-1.41.71.61.5-1.6-1.7-1.7-1.5-1.61.5-1.6
Cocaine response before conditioning0.91.11.41.01.0-0.9-1.1-1.01.11.01.01.01.0-1.11.2
Saline control response0.00.00.1-0.3-0.3-0.2-0.0-0.30.00.10.2-0.10.30.00.2
Bone: connectivity density1.01.62.01.31.3-1.1-1.2-1.41.31.21.21.31.1-1.41.3
Bone: cortical apparent density1.01.71.81.31.3-1.3-1.3-1.31.31.31.31.31.3-1.31.2
Bone: cortical area0.10.20.40.60.6-0.2-0.30.00.30.20.20.50.3-0.50.5
Bone: cortical porosity1.01.11.21.01.0-1.0-1.1-1.11.11.11.11.01.0-1.11.1
Bone: cortical porosity1.51.61.81.31.3-1.2-1.3-1.31.31.31.31.21.2-1.31.3
Bone: cortical thickness1.83.04.12.02.0-1.5-1.7-1.41.71.61.61.81.6-1.81.8
Bone: cortical thickness0.70.91.41.21.2-0.8-0.9-0.80.90.80.81.10.9-1.11.0
Bone: cortical tissue density1.01.51.71.31.3-1.3-1.2-1.21.21.21.31.31.2-1.21.2
Condit. Reinf. active minus inactive responses0.00.00.10.10.1-0.1-0.10.00.10.00.00.20.0-0.10.2
Condit. Reinf. active-inactive response ratio0.50.50.60.80.8-0.8-0.7-0.60.70.70.70.70.8-0.60.8
Condit. Reinf. active responses0.30.40.5-0.6-0.60.60.70.7-0.7-0.7-0.7-0.6-0.70.7-0.5
Condit. Reinf. inactive responses1.01.31.5-1.2-1.21.21.21.1-1.1-1.2-1.2-1.1-1.21.1-0.9
Incentive salience index mean0.00.00.10.20.20.10.00.2-0.0-0.1-0.10.3-0.1-0.20.3
Condit. Reinf. lever presses0.00.10.30.40.4-0.1-0.10.10.10.0-0.00.50.1-0.40.3
Condit. Reinf. active minus inactive responses2.43.85.4-1.8-1.82.12.02.3-2.0-2.1-2.1-1.5-2.11.6-1.5
Condit. Reinf. active-inactive response ratio0.61.01.3-1.1-1.11.01.11.1-1.1-1.1-1.0-0.8-1.10.9-0.8
Condit. Reinf. active responses1.52.13.7-1.3-1.31.71.61.9-1.5-1.6-1.7-1.0-1.71.0-1.0
Condit. Reinf. inactive responses0.10.10.30.20.20.30.10.5-0.1-0.2-0.30.4-0.2-0.40.2
Condit. Reinf. lever presses0.71.02.11.01.0-0.7-0.9-0.50.90.80.81.40.8-1.41.4
Condit. Reinf. lever reinforcers received1.01.42.6-1.0-1.01.41.31.6-1.2-1.3-1.4-0.7-1.30.7-0.7
Conditioned reinforcement - actives0.10.41.0-1.0-1.00.10.40.1-0.5-0.3-0.2-0.9-0.10.9-0.8
Conditioned reinforcement - inactives0.00.10.20.20.2-0.4-0.3-0.10.30.30.4-0.00.50.00.0
Conditioned locomotion0.10.20.80.00.0-0.7-0.4-0.90.40.50.6-0.00.50.00.1
Patch foraging indifference point 0 sec0.10.40.7-0.5-0.50.80.70.8-0.7-0.8-0.8-0.3-0.60.2-0.3
Patch foraging indifference point AUC0.10.10.40.30.30.60.30.6-0.2-0.4-0.40.0-0.70.0-0.0
Delay disc. indifference point, 0s delay0.20.30.40.30.3-0.6-0.6-0.60.50.60.60.40.7-0.40.5
Delay disc. indifference point, 16s delay0.10.10.40.10.1-0.6-0.4-0.50.30.50.5-0.10.60.2-0.0
Delay disc. indifference point, 2s delay0.00.00.2-0.0-0.0-0.4-0.2-0.30.10.20.3-0.00.30.1-0.2
Delay disc. indifference point, 24s delay0.10.20.50.40.4-0.6-0.5-0.70.50.50.50.30.6-0.20.3
Delay disc. indifference point, 4s delay0.10.10.30.20.2-0.5-0.4-0.60.30.40.50.10.5-0.10.2
Delay disc. indifference point, 8s delay0.00.10.2-0.3-0.30.10.20.1-0.2-0.2-0.2-0.4-0.10.4-0.5
Indifference point function ln k0.10.40.6-0.8-0.80.60.60.3-0.6-0.6-0.5-0.8-0.50.8-0.7
Indifference point function log k0.10.40.6-0.8-0.80.60.60.3-0.6-0.6-0.5-0.8-0.50.8-0.7
Patch foraging total patch changes 0 sec0.20.50.9-0.6-0.60.90.80.9-0.7-0.8-0.9-0.4-0.80.3-0.3
Patch foraging total patch changes 12 sec0.00.10.20.20.20.20.10.4-0.0-0.1-0.10.3-0.2-0.30.4
Patch foraging total patch changes 18 sec0.10.20.7-0.3-0.30.60.50.8-0.5-0.5-0.5-0.3-0.50.2-0.3
Patch foraging total patch changes 24 sec0.10.20.70.10.10.80.40.7-0.3-0.5-0.60.1-0.7-0.20.2
Patch foraging total patch changes 6 sec0.40.71.2-0.6-0.60.90.91.1-0.8-0.9-1.0-0.6-0.90.6-0.7
Patch foraging time to switch 0 sec0.62.43.91.21.2-2.0-1.6-1.71.61.71.71.21.9-1.21.1
Patch foraging water rate 0 sec1.03.95.3-1.9-1.92.32.02.0-2.0-2.1-2.1-1.7-2.21.8-1.6
Patch foraging water rate 12 sec1.66.38.3-2.3-2.32.92.62.7-2.6-2.7-2.7-2.0-2.92.0-2.1
Patch foraging water rate 18 sec0.20.50.8-0.7-0.70.90.70.4-0.7-0.8-0.8-0.4-0.90.5-0.4
Patch foraging water rate 24 sec0.30.50.7-0.6-0.60.70.70.8-0.7-0.8-0.8-0.5-0.70.5-0.6
Patch foraging water rate 6 sec1.42.13.0-1.4-1.41.71.51.3-1.5-1.5-1.5-1.3-1.61.3-1.2
Seeking ratio, delayed vs. immediate footshock0.40.60.8-0.7-0.70.80.80.9-0.8-0.8-0.9-0.9-0.70.8-0.8
Distance traveled before self-admin0.10.30.6-0.7-0.7-0.40.0-0.4-0.10.10.2-0.70.60.8-0.6
Distance traveled after self-admin0.81.31.8-1.4-1.40.91.10.9-1.1-1.1-1.0-1.3-0.81.3-1.3
Extensor digitorum longus weight8.232.933.7-5.7-5.75.85.85.6-5.8-5.8-5.7-5.7-5.85.7-5.7
Bone: elastic displacement0.30.40.6-0.7-0.70.80.60.6-0.7-0.6-0.6-0.6-0.70.7-0.7
Bone: elastic work0.00.00.10.10.10.20.10.2-0.1-0.1-0.10.1-0.2-0.0-0.1
Bone: endosteal estimation1.94.75.2-2.0-2.02.32.22.3-2.2-2.2-2.2-2.1-2.22.0-2.1
Bone: endosteal perimeter2.86.97.8-2.4-2.42.82.72.8-2.7-2.7-2.7-2.6-2.72.5-2.5
Epididymis fat weight0.00.00.0-0.2-0.20.00.0-0.1-0.1-0.00.00.0-0.0-0.0-0.1
Delta time in closed arm before/after self-admin1.41.32.01.21.2-0.9-1.1-1.41.11.11.11.20.9-1.31.1
Delta time in open arm before/after self-admin0.10.20.30.40.4-0.3-0.4-0.20.40.40.30.50.3-0.50.5
Diff in mean of infusions in LGA sessions0.81.41.7-1.3-1.31.21.21.0-1.2-1.1-1.1-1.2-1.21.2-1.1
Delay discount exponential model param0.00.10.20.30.30.1-0.10.10.10.0-0.00.4-0.1-0.50.4
Extinction: sum of active levers before priming0.30.40.5-0.7-0.70.60.70.6-0.7-0.7-0.7-0.7-0.60.7-0.5
Active lever presses in extinction session 60.70.70.9-1.0-1.00.70.70.9-0.7-0.7-0.7-0.9-0.70.8-1.0
Bone: final force0.20.30.9-0.1-0.10.60.60.9-0.5-0.6-0.7-0.2-0.60.2-0.3
Bone: final moment0.00.10.30.30.30.20.10.5-0.1-0.2-0.30.2-0.1-0.20.1
Food consumed during 24 hour testing period0.51.01.3-1.1-1.10.91.00.9-1.0-1.0-0.9-1.1-0.81.1-1.0
Glucose0.91.41.8-1.0-1.01.41.21.2-1.2-1.3-1.3-1.0-1.31.1-1.2
Heart weight1.11.83.0-1.6-1.61.01.31.1-1.3-1.2-1.1-1.7-1.01.7-1.5
Delay discount hyperbolic model param0.00.00.10.20.20.30.10.3-0.0-0.1-0.20.2-0.2-0.30.2
Intermittent access intake day 1-15 change0.20.91.30.60.6-1.2-1.0-1.11.01.11.10.91.0-0.90.9
Intermittent access intake escalation0.10.70.90.50.5-0.9-0.8-0.90.80.90.90.80.8-0.90.8
Intermittent access intake escalation 20.00.00.1-0.3-0.3-0.2-0.0-0.2-0.00.10.1-0.20.10.1-0.2
Intermitt. access day 1 inactive lever presses0.34.04.71.91.9-1.9-2.0-2.22.02.02.02.11.9-2.12.1
Intermitt. access day 15 inactive lever presses0.00.20.6-0.7-0.70.00.2-0.1-0.3-0.1-0.1-0.50.10.5-0.4
Intermitt. access escalation Index0.20.51.1-0.7-0.70.60.61.1-0.6-0.6-0.6-0.8-0.50.9-0.5
Intermittent access day 1 total infusions0.30.81.10.90.9-1.0-0.9-1.00.90.90.90.71.0-0.70.7
Intermittent access day 15 total infusions0.71.82.31.11.1-1.5-1.4-1.31.31.41.41.31.4-1.31.3
Intermittent access terminal intake (last 3 days)0.30.61.10.50.5-1.1-0.8-0.80.80.90.90.70.8-0.70.6
Intermittent access total infusions0.20.30.50.40.4-0.7-0.6-0.60.60.60.60.40.6-0.40.4
Intermittent access day 1 locomotion1.62.93.71.61.6-1.8-1.7-1.91.71.71.81.71.7-1.71.6
Intermittent access day 15 total locomotion0.62.34.91.21.2-1.6-1.5-2.21.51.51.61.51.3-1.51.4
Intermittent access total locomotion0.10.10.6-0.2-0.2-0.3-0.1-0.80.10.20.20.1-0.0-0.10.0
Intermittent access standard deviation0.10.30.70.40.4-0.7-0.6-0.90.60.60.70.50.6-0.60.3
Left kidney weight1.08.310.0-3.2-3.22.72.92.8-2.9-2.8-2.7-3.1-2.62.9-3.0
Right kidney weight1.711.613.8-3.6-3.63.03.43.4-3.4-3.3-3.3-3.7-3.03.6-3.5
Cocaine induced anxiety0.00.10.20.20.2-0.5-0.3-0.40.30.40.40.20.4-0.10.1
Post-drug Anxiety2.22.62.91.61.6-1.7-1.6-1.61.61.71.71.51.7-1.51.5
Baseline Anxiety0.61.01.31.11.1-0.8-1.0-0.81.00.90.91.10.8-1.11.0
Tail length0.00.00.00.00.00.1-0.00.1-0.00.00.00.00.0-0.00.1
Length with tail0.52.43.0-1.5-1.51.71.61.7-1.6-1.6-1.7-1.4-1.41.4-1.3
Length without tail2.211.512.9-3.3-3.33.53.53.6-3.5-3.5-3.6-3.3-3.33.2-3.2
Times rat made contact with spout0.40.51.30.50.5-0.8-0.7-1.10.70.80.90.30.7-0.40.4
Lifetime Intake0.10.20.30.50.5-0.5-0.4-0.30.40.40.40.30.4-0.30.2
Liver weight, left3.56.17.6-2.3-2.32.82.52.5-2.5-2.6-2.6-2.3-2.82.2-2.2
Liver weight, right1.11.82.7-0.9-0.91.51.51.6-1.4-1.5-1.6-1.2-1.41.2-1.2
Locomotor activity6.510.211.4-3.4-3.43.23.22.9-3.2-3.1-3.1-3.3-3.13.3-3.1
Locomotor testing distance2.86.88.4-2.9-2.92.62.62.3-2.6-2.5-2.4-2.7-2.52.7-2.6
Locomotor testing rearing1.03.54.3-2.1-2.11.81.81.8-1.8-1.8-1.8-1.8-1.71.8-1.9
Locomotion in novel chamber0.20.30.80.40.4-0.5-0.5-0.50.50.50.60.50.5-0.70.9
Locomotion in novel chamber post-restriction0.30.91.41.01.0-1.2-0.9-0.80.91.01.00.81.1-0.70.8
Fecal boli incidents, locomotor time 10.00.10.20.10.1-0.4-0.2-0.10.20.30.30.20.5-0.20.2
Change in fecal boli incidents, locomotor task0.00.00.10.00.00.30.10.1-0.1-0.2-0.2-0.2-0.40.2-0.1
Time >=10cm from walls, locomotor time 10.20.20.3-0.6-0.60.40.40.2-0.4-0.4-0.4-0.5-0.40.4-0.5
Bouts of movement, locomotor time 10.10.10.2-0.4-0.40.40.30.4-0.3-0.3-0.20.0-0.1-0.20.1
Total resting periods, locomotor time 10.10.10.2-0.4-0.40.40.30.3-0.3-0.3-0.2-0.0-0.2-0.10.1
Rest time, locomotor task time 10.00.00.0-0.0-0.00.20.0-0.1-0.0-0.0-0.10.0-0.1-0.10.1
Distance moved, locomotor task time 10.00.10.20.40.4-0.3-0.3-0.20.30.30.30.30.1-0.20.2
Vertical activity count, locomotor time 10.00.20.40.30.3-0.6-0.4-0.50.40.50.50.20.5-0.20.2
Time >=10cm from walls, locomotor time 20.00.00.10.10.10.20.10.2-0.0-0.1-0.10.1-0.3-0.10.0
Bouts of movement, locomotor time 20.61.93.0-1.7-1.71.21.31.1-1.4-1.3-1.2-1.6-1.01.4-1.4
Total resting periods, locomotor time 20.52.13.4-1.8-1.81.21.41.1-1.4-1.3-1.3-1.6-1.11.5-1.5
Rest time, locomotor task time 20.20.30.50.30.3-0.5-0.5-0.50.50.50.50.60.7-0.60.5
Distance moved, locomotor task time 20.00.00.20.40.40.1-0.1-0.00.10.00.00.1-0.3-0.20.1
Vertical activity count, locomotor time 20.20.40.80.50.5-0.9-0.7-0.90.70.70.80.30.6-0.30.4
Light reinforcement 11.25.56.2-2.1-2.12.52.52.5-2.4-2.5-2.5-2.3-2.52.3-2.1
Light reinforcement 20.10.20.40.60.6-0.2-0.4-0.20.40.30.30.60.3-0.60.5
Bone: marrow area1.94.65.2-2.0-2.02.32.22.2-2.2-2.2-2.2-2.1-2.22.0-2.0
Bone: maximum diameter1.73.54.5-1.5-1.52.12.02.1-1.9-2.0-2.0-1.7-2.01.6-1.7
Bone: maximum force0.10.30.7-0.2-0.20.70.60.8-0.5-0.6-0.7-0.4-0.60.3-0.4
Bone: maximum moment0.00.00.20.10.10.20.20.5-0.1-0.2-0.30.0-0.2-0.1-0.0
Mean time between licks in bursts0.10.40.70.60.6-0.7-0.7-0.90.70.70.70.40.7-0.30.6
Mean num. licks in bursts0.41.12.0-1.4-1.40.91.00.7-1.0-0.9-0.9-1.1-0.91.1-1.1
Cd content in liver1.31.51.81.11.1-1.3-1.2-1.21.21.31.31.11.4-1.11.1
Co content in liver1.21.41.71.31.3-1.1-1.2-1.31.21.21.31.11.2-1.01.1
Cu content in liver0.00.00.10.30.30.10.00.00.0-0.0-0.1-0.1-0.2-0.0-0.0
Fe content in liver0.20.20.4-0.4-0.40.60.60.5-0.6-0.6-0.6-0.4-0.50.3-0.3
K content in liver1.81.82.9-1.2-1.21.51.41.1-1.4-1.4-1.4-1.2-1.71.2-1.2
Mg content in liver1.51.72.1-1.2-1.21.41.31.2-1.3-1.3-1.3-1.3-1.51.2-1.2
Mn content in liver0.00.00.10.20.2-0.1-0.2-0.30.20.10.2-0.00.1-0.00.1
Na content in liver7.38.29.6-2.5-2.53.13.02.9-3.0-3.0-3.1-2.7-3.12.7-2.7
Rb content in liver0.60.70.9-0.9-0.90.90.80.7-0.8-0.8-0.8-0.8-1.00.8-0.8
Se content in liver0.00.00.10.20.2-0.1-0.2-0.30.10.20.20.30.1-0.30.3
Sr content in liver0.00.00.10.30.3-0.2-0.2-0.10.20.20.20.20.2-0.20.2
Zn content in liver0.00.00.2-0.1-0.10.30.20.1-0.2-0.2-0.2-0.1-0.40.0-0.1
Bone: minimum diameter0.00.10.20.20.2-0.3-0.2-0.00.20.20.20.30.4-0.40.4
Time in familiar zone, hab. session 10.00.00.10.30.30.1-0.1-0.10.10.10.00.2-0.1-0.30.2
Time in novel zone, hab. session 10.00.00.10.10.1-0.3-0.2-0.20.20.20.20.10.4-0.00.0
Total zone transitions, hab. session 10.60.81.41.21.2-0.6-0.8-0.80.80.70.71.00.5-1.01.1
Total locomotion distance, hab. session 10.10.10.30.50.5-0.2-0.3-0.30.30.20.20.20.1-0.30.4
Locomotion velocity, hab. session 10.00.00.00.20.2-0.00.0-0.0-0.0-0.0-0.00.0-0.2-0.00.2
Time in familiar zone, hab. session 20.00.10.10.30.3-0.3-0.3-0.10.30.20.20.20.2-0.20.1
Time in novel zone, hab. session 20.00.00.10.00.0-0.1-0.1-0.20.10.10.20.20.2-0.20.2
Total zone transitions, hab. session 20.30.30.7-0.1-0.10.80.60.7-0.6-0.7-0.7-0.5-0.80.4-0.5
Total locomotion distance, hab. session 20.70.91.3-0.7-0.71.01.01.0-1.0-1.0-1.0-1.1-1.11.0-1.0
Locomotion velocity, hab. session 20.40.50.7-0.4-0.40.70.70.7-0.7-0.7-0.7-0.8-0.90.8-0.7
Novel to familiar place preference ratio0.91.11.7-1.3-1.30.91.01.1-1.0-1.0-1.0-1.0-0.91.0-1.1
Novelty place preference0.91.11.7-1.3-1.30.91.11.1-1.1-1.0-1.0-0.9-0.91.0-1.1
Time in novel zone, NPP test1.11.42.0-1.4-1.41.01.21.2-1.2-1.1-1.1-1.0-1.01.1-1.2
Total zone transitions, NPP test0.20.30.8-0.4-0.40.80.50.5-0.5-0.6-0.6-0.2-0.90.2-0.2
Total locomotion distance, NPP test0.60.81.3-0.8-0.81.00.90.9-0.9-0.9-0.9-0.7-1.10.7-0.7
Locomotion velocity, NPP test0.20.30.7-0.5-0.50.60.60.5-0.6-0.6-0.6-0.4-0.80.4-0.3
Intraocular pressure0.00.00.20.10.1-0.10.00.0-0.0-0.0-0.1-0.40.00.4-0.3
Delta distance traveled before/after self-admin1.11.22.0-0.8-0.81.31.21.4-1.1-1.2-1.3-0.7-1.40.7-0.8
Delta ambulatory time before/after self-admin0.30.40.9-0.4-0.40.80.71.0-0.7-0.8-0.8-0.3-0.90.3-0.3
Parametrial fat weight1.02.44.02.02.0-1.4-1.5-1.51.51.51.41.41.5-1.41.3
Pavlov. Cond. lever latency0.10.10.20.30.3-0.5-0.4-0.40.40.40.40.10.5-0.20.1
Pavlov. Cond. magazine entry latency0.70.91.41.11.1-0.8-0.9-0.80.90.80.81.20.8-1.11.0
Pavlov. Cond. change in total contacts0.00.00.0-0.1-0.1-0.00.0-0.1-0.00.00.10.10.0-0.10.2
Pavlov. Cond. index score0.50.71.10.90.9-0.7-0.7-0.70.70.70.71.00.6-1.01.0
Pavlov. Cond. latency score0.20.30.60.60.6-0.3-0.4-0.30.40.40.40.70.3-0.70.7
Pavlov. Cond. lever contacts0.00.00.10.20.20.20.00.1-0.0-0.1-0.10.2-0.2-0.10.1
Pavlov. Cond. magazine entry number1.01.21.6-1.2-1.21.01.10.9-1.1-1.0-1.0-1.3-1.01.2-1.2
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.3-0.30.40.30.4-0.3-0.4-0.4-0.3-0.40.4-0.3
Pavlov. Cond. lever-magazine prob. diff.0.30.30.70.70.7-0.4-0.5-0.40.50.50.50.80.4-0.80.7
Pavlov. Cond. response bias0.40.50.80.80.8-0.5-0.6-0.60.60.60.60.90.5-0.80.7
Pavlov. Cond. lever latency0.30.51.1-0.7-0.70.40.60.3-0.6-0.5-0.5-1.1-0.41.1-1.1
Pavlov. Cond. magazine entry latency3.14.45.42.12.1-2.0-2.1-2.12.12.02.12.11.9-2.22.3
Pavlov. Cond. change in total contacts0.30.61.30.80.8-0.6-0.7-0.60.70.70.71.00.6-1.01.2
Pavlov. Cond. index score0.91.42.11.21.2-0.9-1.1-1.01.11.11.01.40.9-1.41.5
Pavlov. Cond. latency score0.50.91.41.01.0-0.7-0.8-0.80.90.80.81.20.7-1.21.2
Pavlov. Cond. lever contacts0.30.41.00.70.7-0.3-0.5-0.30.60.50.41.00.4-1.01.0
Pavlov. Cond. magazine entry number3.54.65.4-2.3-2.31.92.12.1-2.1-2.1-2.1-2.3-1.92.3-2.3
Pavlov. Cond. intertrial magazine entries0.71.41.9-1.1-1.11.21.21.4-1.2-1.2-1.2-1.2-1.11.2-1.2
Pavlov. Cond. lever-magazine prob. diff.1.01.62.31.31.3-1.0-1.2-1.11.21.11.11.51.0-1.51.5
Pavlov. Cond. response bias1.52.13.31.51.5-1.2-1.4-1.21.41.31.31.71.2-1.71.8
Time in closed arm before self-admin0.10.10.5-0.3-0.3-0.4-0.2-0.70.20.30.4-0.10.40.00.0
Time in closed arm after self-admin0.60.71.70.50.5-0.9-0.9-1.30.90.91.00.60.9-0.70.8
Time in open arm before self-admin0.60.71.4-0.7-0.70.60.71.2-0.7-0.8-0.8-0.9-0.71.0-1.0
Time in open arm after self-admin0.30.30.9-0.5-0.50.50.60.9-0.5-0.6-0.6-0.5-0.50.5-0.5
Bone: periosteal estimation0.92.12.9-1.2-1.21.61.51.7-1.5-1.6-1.6-1.3-1.51.2-1.3
Bone: periosteal perimeter1.52.93.9-1.4-1.41.81.82.0-1.8-1.8-1.8-1.6-1.71.5-1.6
Bone: post-yield work0.10.10.1-0.4-0.40.30.30.2-0.3-0.3-0.3-0.4-0.30.4-0.3
Progressive ratio test 1 active lever presses0.10.10.20.40.4-0.4-0.4-0.30.40.40.40.20.4-0.20.1
Progressive ratio test 1 breakpoint0.10.20.20.50.5-0.5-0.4-0.30.40.40.40.20.4-0.20.2
Progressive ratio test 1 inactive lever presses1.23.24.22.12.1-1.7-1.8-1.61.91.81.71.71.7-1.81.7
Progressive ratio test 2 active lever presses0.10.20.4-0.5-0.50.20.40.2-0.4-0.3-0.3-0.6-0.30.6-0.6
Progressive ratio test 2 breakpoint0.10.20.4-0.5-0.50.20.30.2-0.4-0.3-0.3-0.5-0.30.5-0.6
Progressive ratio test 2 inactive lever presses0.10.20.30.30.3-0.5-0.5-0.50.40.50.50.40.5-0.40.3
Incentive Sensitization - Responses0.10.30.7-0.8-0.80.20.50.3-0.5-0.4-0.4-0.6-0.20.6-0.7
Incentive Sensitization - Breakpoint0.10.20.5-0.7-0.70.10.30.2-0.4-0.3-0.2-0.5-0.10.5-0.6
Sum of active levers in priming session hrs 5-60.10.10.2-0.5-0.50.30.30.1-0.3-0.3-0.3-0.3-0.20.5-0.4
Progressive ratio0.31.01.80.50.5-1.3-1.1-1.21.01.21.30.41.3-0.70.6
Food seeking constrained by brief footshock0.20.30.5-0.5-0.50.70.50.5-0.5-0.5-0.5-0.5-0.60.5-0.5
Seeking ratio, punishment vs. effort2.14.76.7-1.7-1.72.62.32.4-2.2-2.4-2.5-1.6-2.61.8-1.7
Retroperitoneal fat weight0.10.30.70.80.8-0.4-0.4-0.50.40.40.30.60.4-0.80.7
Reaction time number correct0.62.23.0-1.6-1.61.41.51.0-1.5-1.4-1.4-1.6-1.51.7-1.7
Reaction time mean minus median0.00.10.40.20.2-0.1-0.20.30.20.10.10.7-0.1-0.60.6
Reaction time mean minus median AUC0.10.61.40.80.8-0.6-0.7-0.30.70.70.61.20.4-1.11.1
Reaction time num false alarms0.50.81.41.21.2-0.9-0.8-0.70.90.80.80.80.9-0.90.9
Reaction time num false alarms AUC0.10.30.70.80.8-0.6-0.5-0.30.50.40.40.50.5-0.60.6
Reaction time trials correct on left0.62.23.0-1.6-1.61.41.51.0-1.5-1.4-1.4-1.6-1.51.7-1.7
Reaction time trials on left0.72.43.2-1.6-1.61.51.51.1-1.5-1.5-1.5-1.7-1.51.7-1.8
Reaction time mean1.53.44.72.02.0-1.6-1.8-1.51.81.71.72.01.4-2.12.2
Reaction time mean AUC1.02.33.21.71.7-1.3-1.5-1.31.51.41.41.71.2-1.71.8
Median of all reaction times3.85.97.22.72.7-2.2-2.4-2.32.42.32.32.52.1-2.62.7
Reaction time omissions0.20.30.5-0.4-0.40.50.50.7-0.5-0.5-0.6-0.4-0.70.4-0.4
Reaction time false alarm rate1.41.92.71.71.7-1.4-1.3-0.91.31.31.21.41.3-1.51.5
Reaction time premature initiation rate1.52.42.8-1.3-1.31.61.61.7-1.6-1.6-1.6-1.5-1.61.5-1.5
Reaction time premature initiations1.34.04.4-1.8-1.82.02.01.9-2.0-2.0-2.0-2.0-2.12.1-2.1
Std. dev. reaction times0.31.11.91.11.1-0.9-1.0-0.61.01.00.91.30.7-1.41.4
Reaction time trials completed0.72.43.2-1.6-1.61.51.51.1-1.5-1.5-1.5-1.7-1.51.7-1.8
Reaction time trials AUC0.62.02.8-1.5-1.51.31.40.9-1.4-1.4-1.4-1.6-1.41.6-1.7
Run reversals in cocaine runway, females0.00.00.00.20.20.0-0.1-0.20.10.10.1-0.1-0.0-0.0-0.1
Run reversals in cocaine runway, males0.00.00.1-0.2-0.20.30.20.3-0.2-0.2-0.3-0.0-0.30.1-0.1
Latency to leave start box in cocaine runway2.12.94.1-2.0-2.01.21.61.7-1.7-1.6-1.5-1.8-1.21.9-1.9
Latency to leave start box in cocaine runway, F0.70.91.4-1.2-1.20.60.91.0-0.9-0.9-0.8-0.9-0.71.0-0.9
Latency to leave start box in cocaine runway, M5.85.67.0-2.6-2.61.92.32.3-2.3-2.2-2.2-2.6-1.92.6-2.7
Std. dev. time between licks in bursts0.30.50.9-0.5-0.50.90.71.0-0.7-0.8-0.8-0.4-0.80.4-0.4
Total sessions with >9 infusions0.20.20.50.70.7-0.3-0.40.10.40.40.30.40.2-0.50.4
Short access day 1 total inactive lever presses0.40.81.01.01.0-1.0-0.9-0.70.90.90.90.60.9-0.80.8
Short access day 10 total inactive lever presses0.21.53.10.80.8-1.3-1.2-1.81.21.31.31.11.3-1.21.2
Short access day 1 total infusions0.10.20.40.40.4-0.6-0.4-0.20.40.50.50.10.5-0.2-0.0
Short access day 10 total infusions0.81.41.81.41.4-1.2-1.2-0.91.21.21.21.11.0-1.11.0
Short access total infusions0.40.60.90.90.9-0.8-0.8-0.40.80.80.70.70.6-0.70.6
Short access day 1 locomotion0.00.10.20.50.5-0.4-0.3-0.00.30.30.3-0.00.20.0-0.2
Short access day 10 total locomotion0.10.50.90.80.8-0.6-0.7-0.70.70.60.60.90.4-1.00.9
Short access total locomotion0.30.50.70.80.8-0.7-0.7-0.40.70.70.70.70.5-0.70.7
One hour access (0.3 mA shock)0.70.91.5-1.1-1.10.80.90.7-0.9-0.8-0.8-1.0-0.91.0-1.2
Compulsive drug intake1.11.62.1-1.0-1.01.51.31.2-1.3-1.4-1.4-1.2-1.41.3-1.2
One hour access (shock baseline)0.10.20.40.20.2-0.6-0.5-0.50.50.50.60.30.6-0.30.1
Social response proportion0.20.20.40.10.1-0.6-0.5-0.50.40.50.60.30.7-0.30.6
Social responses0.00.00.1-0.2-0.20.20.10.2-0.1-0.2-0.10.3-0.1-0.20.3
Social time0.00.10.3-0.3-0.3-0.4-0.0-0.10.00.10.1-0.10.50.0-0.1
Soleus weight16.849.551.7-7.0-7.07.27.16.9-7.1-7.1-7.0-7.0-7.27.0-7.0
Bone: stiffness0.51.01.4-0.9-0.90.91.11.2-1.0-1.1-1.1-0.9-0.90.8-0.8
Tibialis anterior weight13.747.149.8-6.7-6.76.86.97.1-6.9-6.9-6.9-6.8-6.96.8-6.9
Time to tail flick, vehicle, before self-admin0.20.30.60.50.5-0.4-0.4-0.30.50.40.40.80.2-0.80.8
Time to tail flick, vehicle, after self-admin0.61.23.10.40.4-1.3-1.1-1.81.11.31.40.61.5-0.50.7
Time to tail flick, test, before self-admin1.82.12.61.61.6-1.2-1.4-1.21.41.41.41.51.2-1.61.6
Time to tail flick, test, after self-admin2.42.55.20.90.9-2.3-1.7-1.71.71.92.00.92.1-1.01.0
Delta time to tail flick, vehicle, before/after SA0.70.81.70.40.4-1.0-0.9-1.30.91.01.10.41.3-0.40.5
Delta time to tail flick, test, before/after SA0.20.20.6-0.8-0.8-0.20.20.1-0.3-0.1-0.1-0.60.10.6-0.7
Tibia length0.10.10.30.30.3-0.3-0.3-0.50.30.40.40.40.4-0.40.5
Ambulatory time before self-admin0.00.10.4-0.2-0.2-0.5-0.2-0.50.20.30.3-0.30.60.3-0.2
Ambulatory time after self-admin0.30.50.6-0.8-0.80.50.70.7-0.7-0.7-0.7-0.8-0.50.8-0.8
Bone: tissue strength1.41.51.71.21.2-1.3-1.2-1.11.21.21.21.21.2-1.21.2
Total heroin consumption1.71.92.8-1.7-1.71.01.31.1-1.3-1.2-1.1-1.7-1.11.7-1.6
Bone: trabecular number1.32.43.01.71.7-1.4-1.5-1.51.61.51.51.71.3-1.71.6
Bone: trabecular spacing0.00.10.1-0.3-0.30.20.20.2-0.2-0.2-0.2-0.3-0.20.4-0.2
Bone: trabecular thickness0.50.71.11.11.1-0.7-0.8-0.80.80.80.80.70.7-0.80.7
Bone: trabecular tissue density3.76.57.5-2.3-2.32.72.62.7-2.6-2.6-2.7-2.4-2.72.4-2.5
Water consumed over 24 hours0.20.30.50.50.5-0.7-0.6-0.70.60.60.60.40.7-0.50.5
Number of responses in last shaping day0.00.10.2-0.3-0.3-0.4-0.2-0.20.10.30.3-0.10.20.0-0.1