Plaat3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC mRNA stability Plaat3 0.17 0.1 4.2e-03 0.05 0.01 0.04 -0.01 3.1e-02 1.8e-01 3.1e-02 7.4e-01
2 NAcc mRNA stability Plaat3 0.03 0.02 6.4e-04 0.02 0.01 0.02 0.01 1.8e-04 2.4e-03 2.6e-04 1.8e-03
3 pVTA alternative TSS XM_039101108.2 0.03 0.02 4.1e-03 0.02 0.03 0.04 0.02 1.4e-02 2.3e-03 5.3e-04 5.3e-03
4 Liver intron excision ratio chr1_214212364_214230191 0.07 0.04 1.5e-05 0.05 0.04 0.04 0.05 5.5e-06 9.1e-05 2.6e-05 7.1e-06
5 Liver intron excision ratio chr1_214230293_214237794 0.05 0.03 1.5e-04 0.04 0.03 0.03 0.04 4.3e-05 6.5e-04 1.9e-04 7.0e-05
6 pVTA alternative TSS XM_039101108.2 0.03 0.02 5.8e-03 0.01 0.02 0.04 0.01 5.9e-02 5.7e-03 2.4e-04 2.9e-02
7 pVTA mRNA stability Plaat3 0.1 0.05 2.1e-06 0.04 0.07 0.06 0.07 1.7e-04 3.2e-06 3.2e-05 1.2e-06
8 Brain mRNA stability Plaat3 0.14 0.08 3.9e-09 0.09 0.08 0.1 0 7.2e-09 5.3e-08 2.0e-09 1.1e-01
9 pVTA alternative TSS NM_017060.2 0.03 0.02 6.2e-03 0.02 0.03 0.04 0.02 1.4e-02 3.4e-03 4.9e-04 6.8e-03
10 IL mRNA stability Plaat3 0.36 0.14 1.8e-05 0.16 0.11 0.21 0.03 1.1e-04 1.2e-03 8.0e-06 6.3e-02
11 Adipose gene expression Plaat3 0.33 0.11 0.0e+00 0.19 0.18 0.18 0.19 1.1e-20 4.7e-20 4.5e-20 1.6e-20
12 NAcc isoform ratio XM_039101108.2 0.04 0.02 1.9e-07 0.04 0.04 0.04 0.04 1.0e-06 2.7e-07 2.7e-07 3.9e-07
13 Brain isoform ratio XM_039101108.2 0.02 0.02 5.2e-03 0.01 0.02 0.03 0.02 1.5e-02 2.5e-03 1.2e-03 9.7e-03
14 PL mRNA stability Plaat3 0.06 0.04 5.9e-07 0.02 0.04 0.04 0.03 1.5e-03 3.5e-05 2.9e-05 1.1e-04
15 RMTg gene expression Plaat3 0.27 0.11 8.9e-07 0.21 0.23 0.2 0.23 2.9e-06 8.4e-07 4.4e-06 9.1e-07
16 pVTA gene expression Plaat3 0.5 0.12 0.0e+00 0.52 0.53 0.53 0.53 1.6e-48 1.9e-49 3.3e-49 1.2e-49
17 Liver gene expression Plaat3 0.36 0.14 0.0e+00 0.21 0.26 0.26 0.24 8.1e-23 3.6e-28 3.9e-28 6.0e-27
18 Brain gene expression Plaat3 0.32 0.1 0.0e+00 0.33 0.34 0.36 0.36 1.2e-31 3.7e-33 1.4e-34 5.3e-35
19 NAcc gene expression Plaat3 0.31 0.09 0.0e+00 0.39 0.39 0.39 0.4 3.4e-63 5.3e-63 5.6e-63 2.3e-64
20 PL isoform ratio XM_039101108.2 0.03 0.02 1.6e-03 0.02 0.02 0.02 0.01 2.9e-03 6.4e-03 5.2e-03 1.9e-02
21 LHb gene expression Plaat3 0.53 0.14 2.5e-08 0.32 0.28 0.3 0.3 1.7e-08 2.5e-07 9.4e-08 8.1e-08
22 pVTA isoform ratio NM_017060.2 0.04 0.03 8.8e-03 0.02 0.02 0.02 0.01 9.4e-03 1.1e-02 1.0e-02 2.1e-02
23 BLA gene expression Plaat3 0.1 0.05 4.1e-05 0.09 0.06 0.06 0.07 1.3e-05 5.7e-04 4.8e-04 1.9e-04
24 Adipose mRNA stability Plaat3 0.14 0.09 2.6e-09 0.07 0.07 0.06 0.06 4.4e-08 8.2e-08 6.2e-07 3.0e-07
25 PL gene expression Plaat3 0.08 0.04 3.4e-07 0.06 0.06 0.06 0.06 9.7e-07 5.5e-07 7.2e-07 8.1e-07
26 NAcc isoform ratio NM_017060.2 0.02 0.01 2.8e-03 0 0.01 -0 0 3.8e-01 8.1e-03 6.8e-01 7.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.61.22.4-0.70.60.00.6-0.60.7-0.10.2-0.20.70.60.9-1.1-1.4-1.6-1.51.4-1.5-1.5-1.31.41.41.31.4-1.2-1.0
Area under the delay curve0.50.71.3-0.40.71.10.7-0.71.1-0.50.6-1.2-0.40.10.8-0.8-0.8-0.7-0.80.8-1.0-0.9-1.00.90.90.90.9-1.0-1.1
BMI with tail3.813.322.6-1.81.83.01.8-1.84.30.50.0-3.22.82.82.6-3.3-3.7-4.5-4.64.5-4.5-4.7-4.74.64.64.74.6-4.7-3.8
BMI without tail0.42.35.0-0.30.70.90.7-0.71.40.2-0.1-1.00.81.11.1-1.2-1.4-1.8-1.81.8-1.8-2.0-2.02.02.02.12.2-2.2-2.2
Body weight1.88.016.00.00.11.80.1-0.13.12.2-1.8-2.13.43.90.8-1.5-2.0-3.3-3.33.3-3.1-3.7-3.73.83.53.73.8-4.0-2.7
Weight adjusted by age0.20.62.51.1-1.3-0.3-1.31.3-0.01.0-0.80.21.61.3-0.40.10.5-0.5-0.50.5-0.4-0.7-0.60.70.50.20.7-0.60.1
Bone surface1.22.36.10.0-0.6-0.4-0.60.61.01.3-1.10.12.52.10.3-0.7-1.5-2.2-2.31.8-1.9-2.2-1.81.82.01.41.8-1.6-0.6
Bone volume0.81.64.2-0.70.1-0.30.0-0.01.00.6-0.40.11.81.30.7-1.0-1.6-2.1-2.01.7-1.7-1.9-1.51.51.61.21.5-1.3-0.5
Breakpoint value in progressive ratio session0.91.55.81.3-1.5-2.4-1.71.7-1.71.8-1.72.11.51.7-1.51.40.70.20.2-0.40.10.10.2-0.5-0.20.2-0.10.20.9
Number of licking bursts0.00.00.20.3-0.5-0.0-0.50.50.20.3-0.20.00.40.3-0.1-0.00.1-0.2-0.00.1-0.1-0.1-0.10.20.00.00.1-0.10.0
Context. condit. distance diff. score0.70.81.8-1.11.30.31.3-1.30.2-1.21.3-0.2-0.6-1.01.3-1.2-0.8-0.6-0.70.8-0.4-0.6-0.80.80.80.40.7-0.6-1.1
Locomotion velocity, session 10.30.31.3-0.40.80.20.7-0.70.0-0.50.6-0.3-1.1-0.30.5-0.4-0.6-0.2-0.30.4-0.5-0.2-0.30.40.50.90.3-0.5-0.9
Locomotion distance, session 11.11.43.8-0.81.10.81.0-1.00.9-0.30.6-1.0-0.50.41.0-1.1-1.3-1.2-1.31.4-1.5-1.3-1.41.31.52.01.2-1.4-1.5
Locomotion velocity, session 20.70.82.90.4-0.40.1-0.50.50.61.2-0.9-0.31.01.7-0.2-0.3-0.4-0.9-1.00.8-1.0-1.0-1.01.21.21.71.1-1.2-0.6
Locomotion distance, session 20.20.31.5-0.00.50.40.5-0.50.3-0.00.2-0.6-0.90.30.1-0.1-0.4-0.3-0.50.3-0.7-0.4-0.50.50.81.20.4-0.6-0.8
Locomotion velocity, session 34.55.28.9-2.12.52.72.4-2.43.0-1.01.4-2.7-0.20.52.3-2.4-2.3-2.3-2.52.7-2.6-2.5-2.62.22.62.22.2-2.5-2.3
Locomotion distance, session 30.40.40.8-0.40.70.70.7-0.70.7-0.10.3-0.7-0.20.30.5-0.6-0.4-0.5-0.70.7-0.7-0.7-0.70.70.80.80.6-0.9-0.9
Stereotopy head waving bouts, day 33.44.05.8-2.02.32.12.3-2.32.2-1.71.9-2.1-0.7-0.52.3-2.4-2.3-1.9-1.92.0-2.2-1.9-2.01.92.01.92.1-1.8-2.2
Stereotopy head waving duration, day 31.01.22.1-1.41.41.01.5-1.51.1-1.11.2-0.9-0.5-0.51.4-1.3-1.3-1.0-1.01.2-1.1-0.9-1.01.01.00.71.1-0.8-1.0
Locomotion velocity, session 71.51.72.7-1.61.61.31.6-1.61.4-0.91.1-1.3-0.5-0.21.4-1.4-1.5-1.2-1.51.3-1.5-1.2-1.20.91.51.51.1-1.1-1.2
Locomotion distance, session 70.91.12.6-0.61.01.31.1-1.11.1-0.81.0-1.4-0.5-0.31.2-1.0-1.0-0.8-1.11.0-1.1-1.1-1.11.11.31.01.2-1.2-1.6
Stereotopy head waving bouts, day 70.20.30.9-1.00.5-0.10.5-0.50.60.1-0.10.10.50.40.4-0.5-1.0-0.8-0.70.6-0.8-0.4-0.50.30.50.70.2-0.10.2
Stereotopy head waving duration, day 70.40.42.1-0.1-0.4-0.9-0.40.40.01.2-1.20.71.01.4-0.40.1-0.4-0.7-0.60.6-0.6-0.4-0.40.40.50.90.2-0.30.5
Locomotion velocity, session 80.30.33.10.4-0.1-0.9-0.10.1-1.0-0.20.20.7-1.8-0.4-0.40.7-0.30.50.4-0.6-0.00.60.3-0.3-0.20.5-0.60.4-0.3
Locomotion distance, session 81.21.83.2-1.71.80.31.8-1.80.5-1.41.6-0.4-1.1-0.91.7-1.5-1.8-1.2-1.31.2-1.3-1.0-1.21.21.41.51.0-0.9-1.5
Degree of sensitization distance1.41.53.0-0.91.01.31.0-1.01.3-0.81.0-1.30.2-0.21.4-1.4-1.3-1.4-1.41.4-1.3-1.4-1.41.61.41.11.7-1.4-1.5
Degree of sensitization stereotypy0.30.31.2-0.3-0.3-0.7-0.30.30.20.9-0.80.61.11.1-0.30.0-0.5-0.6-0.60.4-0.5-0.3-0.30.10.30.70.0-0.00.6
Conditioned locomotion0.20.20.70.5-0.40.3-0.40.40.40.6-0.5-0.40.20.8-0.30.2-0.1-0.3-0.20.2-0.3-0.3-0.20.60.40.60.6-0.5-0.4
Cocaine response after cond. corrected0.81.23.6-1.11.61.91.6-1.61.4-1.31.4-1.8-1.4-1.21.2-0.9-0.9-0.2-0.30.5-0.4-0.4-0.40.20.40.30.3-0.5-1.3
Cocaine response after cond. not corrected0.50.71.7-1.01.31.21.3-1.30.9-1.01.1-1.1-1.0-0.91.0-0.8-0.8-0.3-0.40.5-0.5-0.5-0.40.20.50.30.3-0.5-1.1
Cocaine response before conditioning0.91.14.70.8-1.3-2.2-1.31.3-1.71.3-1.32.01.20.9-1.00.90.80.2-0.1-0.40.30.10.2-0.4-0.1-0.2-0.40.51.1
Saline control response1.11.65.11.8-2.0-0.9-2.02.0-0.42.2-2.00.62.02.3-1.20.80.9-0.1-0.70.3-0.0-0.7-0.80.60.80.60.5-0.9-0.2
Bone: connectivity density1.11.73.6-0.0-0.2-0.2-0.20.20.80.8-0.6-0.11.81.70.5-0.8-1.2-1.8-1.91.7-1.6-1.9-1.61.81.81.31.7-1.7-1.0
Bone: cortical apparent density0.91.42.71.3-1.4-1.2-1.41.4-1.40.9-1.11.20.60.5-1.31.11.61.21.4-1.11.41.21.3-1.1-1.4-0.9-1.00.91.2
Bone: cortical area0.40.71.90.3-0.50.1-0.50.50.51.0-0.8-0.21.41.40.1-0.5-0.1-1.0-1.21.0-0.8-1.2-1.20.81.10.91.0-1.0-0.2
Bone: cortical porosity0.91.03.00.5-0.5-1.7-0.50.5-1.70.4-0.51.6-0.8-0.3-1.01.10.61.00.9-1.20.71.11.1-1.0-0.9-0.3-1.21.10.9
Bone: cortical porosity0.80.83.00.6-0.7-1.7-0.70.7-1.60.6-0.71.6-0.8-0.0-1.01.10.50.80.7-1.00.40.90.9-0.9-0.70.0-1.00.90.8
Bone: cortical thickness1.72.98.02.8-2.6-1.1-2.62.6-1.22.8-2.81.01.52.5-2.21.82.41.00.7-0.81.10.40.3-0.6-0.4-0.1-0.5-0.10.8
Bone: cortical thickness0.20.31.31.1-0.60.5-0.60.6-0.10.7-0.6-0.5-0.40.6-0.70.70.90.60.3-0.40.30.1-0.0-0.4-0.0-0.1-0.1-0.3-0.4
Bone: cortical tissue density1.01.73.01.5-1.5-1.2-1.51.5-1.41.1-1.21.30.60.6-1.51.21.71.31.5-1.21.41.21.4-1.2-1.5-1.0-1.00.91.2
Condit. Reinf. active minus inactive responses0.40.42.20.3-0.41.4-0.50.51.50.9-0.8-1.30.61.2-0.30.20.3-0.3-0.40.4-0.1-0.4-0.40.40.5-0.20.4-0.50.1
Condit. Reinf. active-inactive response ratio0.40.51.00.7-0.80.5-0.90.90.40.8-0.9-0.40.30.6-0.81.00.90.60.5-0.50.80.50.5-0.5-0.5-1.0-0.60.50.8
Condit. Reinf. active responses0.60.84.2-0.30.11.80.0-0.02.00.5-0.4-1.70.81.10.3-0.6-0.2-0.9-0.90.9-0.7-0.9-0.81.00.80.31.0-0.9-0.2
Condit. Reinf. inactive responses0.91.22.2-1.31.21.11.1-1.11.4-0.60.7-1.10.10.11.2-1.5-1.2-1.3-1.11.1-1.5-1.1-0.91.20.91.11.3-0.9-0.7
Incentive salience index mean0.71.03.20.0-0.11.6-0.10.11.80.7-0.6-1.61.01.40.2-0.5-0.2-1.0-1.01.1-0.8-1.2-1.11.11.10.61.2-1.2-0.6
Condit. Reinf. lever presses0.81.12.1-0.40.00.80.1-0.11.20.7-0.5-0.81.31.30.5-0.8-0.5-1.3-1.41.5-1.2-1.5-1.41.41.41.01.4-1.4-0.7
Condit. Reinf. active minus inactive responses0.10.10.6-0.80.1-0.70.1-0.1-0.2-0.1-0.00.70.3-0.2-0.0-0.0-0.4-0.1-0.3-0.10.00.20.1-0.5-0.1-0.3-0.50.60.7
Condit. Reinf. active-inactive response ratio0.50.84.7-2.21.30.91.3-1.31.5-0.80.8-0.80.3-0.51.0-0.9-1.5-1.0-0.70.6-0.7-0.3-0.20.10.3-0.10.20.30.4
Condit. Reinf. active responses0.10.10.40.1-0.5-0.6-0.50.5-0.30.5-0.60.60.50.5-0.30.20.1-0.0-0.3-0.00.1-0.1-0.2-0.10.1-0.0-0.20.10.4
Condit. Reinf. inactive responses0.50.72.71.7-1.2-1.3-1.21.2-1.50.9-0.81.2-0.10.5-0.90.81.10.80.2-0.50.40.2-0.0-0.20.00.1-0.3-0.1-0.1
Condit. Reinf. lever presses0.50.72.80.2-0.8-0.8-0.90.90.01.2-1.10.61.71.4-0.2-0.2-0.3-0.9-1.20.8-0.7-0.9-1.00.70.90.90.7-0.70.1
Condit. Reinf. lever reinforcers received0.20.30.70.3-0.8-0.8-0.80.8-0.40.8-0.80.80.70.7-0.60.30.30.0-0.3-0.10.1-0.0-0.1-0.20.1-0.1-0.30.10.6
Conditioned reinforcement - actives0.10.21.3-0.80.2-1.10.2-0.2-0.7-0.10.11.00.3-0.30.1-0.2-0.4-0.4-0.1-0.1-0.00.20.3-0.1-0.2-0.1-0.30.81.0
Conditioned reinforcement - inactives0.30.92.7-1.61.11.31.1-1.11.4-0.70.7-1.10.4-0.21.2-1.3-0.8-1.1-1.01.0-0.7-0.7-0.61.00.70.20.6-0.20.2
Conditioned locomotion1.42.15.9-2.22.12.42.1-2.11.6-2.22.1-2.1-1.0-1.92.1-1.9-0.6-0.6-0.40.8-0.1-0.2-0.20.50.2-0.50.30.0-0.5
Patch foraging indifference point 0 sec0.10.31.70.0-0.10.2-0.10.10.30.7-0.7-0.21.30.70.1-0.00.4-0.5-0.60.7-0.2-0.6-0.60.70.6-0.20.6-0.7-0.2
Patch foraging indifference point AUC0.51.33.61.3-1.8-1.4-1.81.8-0.71.8-1.71.31.91.6-1.40.90.60.10.0-0.50.20.00.2-0.4-0.20.0-0.30.41.3
Delay disc. indifference point, 0s delay1.82.03.2-1.41.71.71.8-1.81.6-1.61.7-1.7-1.6-0.61.5-1.5-1.8-1.0-0.81.0-1.4-1.0-1.21.10.91.61.2-1.0-1.7
Delay disc. indifference point, 16s delay0.50.72.3-0.50.51.40.4-0.41.5-0.10.2-1.30.70.30.7-0.9-0.4-0.8-1.10.9-0.8-0.9-0.80.71.00.30.9-0.8-0.4
Delay disc. indifference point, 2s delay0.91.12.0-1.21.01.11.1-1.11.3-1.11.2-1.1-0.8-0.51.3-1.3-1.4-1.1-0.80.9-1.1-0.9-0.90.90.70.90.9-0.7-1.0
Delay disc. indifference point, 24s delay0.10.20.80.9-0.40.8-0.50.50.40.1-0.0-0.8-0.00.30.1-0.30.5-0.0-0.40.3-0.2-0.4-0.50.50.6-0.00.4-0.6-0.6
Delay disc. indifference point, 4s delay0.80.82.1-0.20.71.30.8-0.81.1-0.30.4-1.3-0.30.50.7-0.7-0.5-0.6-0.70.9-0.8-1.0-1.21.21.01.01.1-1.3-1.4
Delay disc. indifference point, 8s delay0.20.32.1-0.20.60.30.6-0.60.0-0.90.9-0.3-1.5-0.70.3-0.1-0.60.20.1-0.2-0.30.1-0.10.00.00.30.0-0.0-0.7
Indifference point function ln k1.13.49.7-2.12.82.92.8-2.81.6-2.92.8-2.5-3.1-2.62.1-1.4-0.80.20.30.4-0.00.10.10.4-0.0-0.70.2-0.3-1.8
Indifference point function log k1.13.49.7-2.12.82.92.8-2.81.6-2.92.8-2.5-3.1-2.62.1-1.4-0.80.20.30.4-0.00.10.10.4-0.0-0.70.2-0.3-1.8
Patch foraging total patch changes 0 sec0.10.21.20.5-0.4-0.1-0.40.4-0.10.9-0.80.11.10.7-0.20.30.8-0.0-0.20.40.2-0.3-0.30.50.3-0.40.4-0.5-0.1
Patch foraging total patch changes 12 sec1.82.48.11.7-2.0-2.1-1.91.9-1.32.8-2.61.82.52.8-1.51.21.0-0.4-0.70.3-0.4-0.7-0.80.50.70.90.5-0.80.5
Patch foraging total patch changes 18 sec0.30.72.70.8-1.2-1.0-1.21.2-0.61.4-1.40.91.61.0-0.90.70.60.00.0-0.20.2-0.00.1-0.2-0.2-0.2-0.20.20.8
Patch foraging total patch changes 24 sec0.82.710.41.7-1.70.0-1.81.80.52.7-2.3-0.23.23.1-0.70.01.0-1.0-1.71.3-0.8-1.7-1.71.51.70.91.4-1.8-0.3
Patch foraging total patch changes 6 sec0.40.71.60.7-0.60.1-0.50.50.31.0-0.9-0.21.31.3-0.1-0.10.1-0.7-1.10.9-0.7-1.0-1.21.01.20.51.0-1.2-0.7
Patch foraging time to switch 0 sec0.41.54.2-0.60.4-0.40.3-0.30.4-0.20.30.11.00.71.0-1.4-1.6-1.9-1.91.5-1.9-1.5-1.61.41.72.01.5-1.3-1.0
Patch foraging water rate 0 sec0.20.94.8-0.10.31.60.3-0.30.7-0.50.4-1.2-0.8-1.0-0.10.41.31.21.1-0.71.30.80.9-0.8-1.0-2.2-0.90.70.5
Patch foraging water rate 12 sec0.41.66.0-0.61.22.51.2-1.21.0-1.51.3-2.0-2.0-1.80.5-0.20.91.41.3-0.71.31.01.0-0.8-0.9-1.7-0.70.5-0.3
Patch foraging water rate 18 sec0.61.28.0-0.61.32.81.2-1.21.8-1.11.1-2.6-1.2-0.71.0-0.80.10.10.10.60.1-0.4-0.40.30.2-0.30.4-0.8-1.3
Patch foraging water rate 24 sec0.60.82.3-0.60.91.50.8-0.80.9-1.31.2-1.2-1.5-1.40.5-0.10.20.80.8-0.40.70.60.4-0.7-0.6-1.4-0.70.5-0.2
Patch foraging water rate 6 sec0.60.83.8-0.20.92.00.9-0.90.8-0.90.9-1.7-1.4-1.30.5-0.20.91.00.8-0.40.90.60.5-0.7-0.4-1.2-0.50.1-0.5
Seeking ratio, delayed vs. immediate footshock0.20.32.1-0.10.21.50.2-0.21.30.3-0.1-1.40.20.40.3-0.40.1-0.3-0.40.5-0.1-0.5-0.40.70.50.20.6-0.6-0.4
Distance traveled before self-admin0.40.93.4-0.2-0.40.0-0.30.30.81.1-1.0-0.11.81.8-0.0-0.4-0.5-1.2-1.21.1-0.9-1.2-1.11.01.11.01.2-1.00.1
Distance traveled after self-admin0.40.81.61.0-1.2-1.1-1.21.2-0.91.2-1.21.10.90.8-1.10.90.90.50.5-0.60.70.40.6-0.4-0.6-0.5-0.30.41.0
Extensor digitorum longus weight1.76.929.42.5-2.7-1.0-2.62.60.44.4-3.80.54.45.4-1.40.40.2-2.0-2.32.1-1.6-2.6-2.52.52.53.12.6-3.0-1.0
Bone: elastic displacement0.50.71.70.50.0-0.60.0-0.0-1.3-0.20.10.7-1.2-0.7-0.50.61.11.31.2-1.01.21.11.0-0.8-0.9-0.7-0.90.70.2
Bone: elastic work0.40.52.01.4-0.8-0.5-0.80.8-0.81.1-1.00.30.41.1-0.60.30.90.20.10.10.1-0.3-0.50.30.41.00.4-0.8-0.7
Bone: endosteal estimation3.07.312.8-3.23.02.73.0-3.03.1-2.62.9-2.7-0.3-1.33.4-3.4-3.6-2.9-2.72.7-2.8-2.6-2.62.52.41.92.5-1.9-2.4
Bone: endosteal perimeter2.97.114.4-3.73.22.73.2-3.23.3-2.83.0-2.6-0.7-1.63.3-3.2-3.8-2.9-2.62.4-2.9-2.3-2.22.22.21.52.2-1.4-1.9
Epididymis fat weight0.84.111.9-3.43.02.13.0-3.02.3-2.02.1-1.80.4-1.12.8-2.8-2.2-2.0-1.62.0-1.5-1.5-1.41.51.30.91.5-1.0-1.0
Delta time in closed arm before/after self-admin0.70.72.40.50.41.20.3-0.30.70.6-0.5-1.20.10.80.4-0.40.4-0.3-0.71.0-0.5-0.9-1.10.91.10.70.8-1.6-1.5
Delta time in open arm before/after self-admin0.50.64.60.4-1.1-0.5-1.11.10.11.2-1.00.52.21.4-0.60.30.4-0.5-0.50.3-0.1-0.5-0.30.40.3-0.10.5-0.10.9
Diff in mean of infusions in LGA sessions0.50.93.40.8-0.7-1.4-0.80.8-1.21.8-1.81.21.31.7-1.11.11.20.20.0-0.00.1-0.2-0.10.10.10.10.3-0.50.4
Delay discount exponential model param0.40.51.10.1-0.4-1.0-0.40.4-1.00.4-0.51.10.2-0.2-0.70.70.70.70.7-0.70.90.81.0-0.9-0.8-0.7-0.90.91.0
Extinction: sum of active levers before priming0.71.04.40.5-0.6-0.6-0.70.70.11.6-1.40.42.12.1-0.4-0.0-0.1-0.9-0.90.9-0.7-1.1-0.91.00.91.31.0-1.1-0.2
Active lever presses in extinction session 61.11.14.50.7-1.2-2.1-1.31.3-1.21.7-1.51.91.71.7-0.90.60.3-0.5-0.40.3-0.3-0.5-0.20.30.20.50.6-0.20.7
Bone: final force1.01.64.00.3-0.5-0.0-0.50.50.61.0-0.8-0.21.91.70.3-0.9-0.8-1.6-1.61.5-1.5-1.8-1.81.41.62.01.5-1.6-0.8
Bone: final moment1.01.64.60.3-0.4-0.2-0.40.40.41.1-0.9-0.01.91.80.3-0.9-0.7-1.6-1.61.5-1.5-1.8-1.91.41.62.11.5-1.6-0.8
Food consumed during 24 hour testing period0.20.32.20.8-1.0-0.3-1.01.0-0.10.3-0.40.41.50.1-0.30.00.40.10.1-0.10.50.10.2-0.2-0.3-0.8-0.30.30.6
Glucose2.64.18.6-2.62.92.02.9-2.91.6-2.92.9-1.9-1.7-1.92.6-2.4-2.4-1.5-1.41.4-1.9-1.2-1.31.11.31.31.2-1.0-1.9
Heart weight2.54.17.3-2.12.72.12.7-2.72.2-1.92.0-2.2-1.1-0.62.3-2.2-2.4-1.7-1.61.9-1.8-1.6-1.81.81.82.01.8-1.9-2.5
Delay discount hyperbolic model param0.50.61.10.4-0.6-0.9-0.60.6-1.00.5-0.61.00.3-0.1-0.80.80.80.80.8-0.80.90.91.0-0.9-0.9-0.8-0.90.91.1
Intermittent access intake day 1-15 change0.10.52.0-0.60.1-0.40.1-0.1-0.5-0.70.60.5-0.2-1.10.10.10.20.40.6-0.70.60.80.9-1.1-0.9-1.1-1.01.41.3
Intermittent access intake escalation0.10.82.7-0.60.0-0.80.0-0.0-0.8-0.80.70.8-0.4-1.3-0.00.20.10.50.8-0.90.60.91.1-1.3-1.1-1.1-1.11.71.5
Intermittent access intake escalation 20.20.31.4-0.60.1-0.70.0-0.0-0.7-0.30.20.70.4-0.50.1-0.10.30.00.1-0.30.20.30.4-0.7-0.4-0.8-0.50.91.2
Intermitt. access day 1 inactive lever presses0.10.72.20.0-0.3-0.7-0.30.3-0.7-0.70.40.8-1.0-1.3-0.30.40.00.70.9-1.10.81.11.2-1.0-1.1-0.9-1.21.51.1
Intermitt. access day 15 inactive lever presses0.42.46.8-2.21.52.31.5-1.52.6-0.10.3-2.11.50.91.4-1.7-1.1-1.8-1.81.9-1.2-1.5-1.41.51.50.91.4-1.2-0.1
Intermitt. access escalation Index0.20.62.4-0.60.91.50.9-0.91.0-0.80.7-1.3-1.4-0.90.4-0.2-0.00.60.5-0.30.50.60.5-0.5-0.4-0.5-0.50.3-0.2
Intermittent access day 1 total infusions3.410.220.3-4.03.94.43.9-3.94.5-2.73.1-4.3-0.6-0.73.8-4.0-3.5-3.1-2.73.1-2.8-2.5-2.52.82.52.52.5-2.3-2.6
Intermittent access day 15 total infusions1.84.413.4-3.73.22.43.1-3.12.4-2.83.0-2.2-1.1-1.92.8-2.7-2.4-1.7-1.11.3-1.4-0.8-0.70.80.70.70.6-0.1-0.6
Intermittent access terminal intake (last 3 days)3.76.516.8-4.13.53.03.5-3.53.2-2.42.8-2.8-0.2-0.93.2-3.4-2.9-2.7-2.22.4-2.3-1.8-1.81.81.81.71.7-1.2-1.2
Intermittent access total infusions6.17.315.9-4.03.73.33.6-3.63.4-2.63.0-3.2-0.6-1.03.4-3.5-3.1-2.7-2.32.5-2.4-1.9-1.92.01.91.91.8-1.5-1.7
Intermittent access day 1 locomotion3.36.012.2-3.03.03.52.9-2.93.5-1.72.1-3.4-0.0-0.32.9-3.0-2.4-2.4-2.22.5-2.1-2.1-1.92.32.01.82.0-1.9-2.1
Intermittent access day 15 total locomotion1.14.111.2-3.32.82.72.8-2.82.8-1.61.8-2.50.6-0.52.5-2.6-2.0-2.2-1.82.0-1.5-1.5-1.41.51.41.01.5-1.0-0.8
Intermittent access total locomotion8.410.120.6-4.53.94.33.9-3.94.5-2.32.7-4.10.7-0.53.9-4.1-3.2-3.4-3.13.3-2.7-2.7-2.52.82.62.02.5-2.0-1.8
Intermittent access standard deviation0.10.31.7-1.31.00.31.0-1.00.2-0.80.7-0.2-0.2-1.00.8-0.6-0.4-0.3-0.30.2-0.10.00.0-0.30.0-0.3-0.10.40.3
Left kidney weight0.43.28.1-2.12.12.62.1-2.12.9-1.61.8-2.40.2-0.52.1-2.2-2.2-1.7-1.51.6-1.6-1.3-1.21.51.41.21.4-1.1-1.3
Right kidney weight0.21.43.1-1.51.31.61.4-1.41.8-1.01.1-1.50.5-0.21.4-1.6-1.4-1.2-1.11.1-1.0-0.9-0.81.10.90.81.1-0.8-0.7
Cocaine induced anxiety0.00.10.5-0.1-0.2-0.3-0.20.20.10.2-0.20.30.50.1-0.40.3-0.10.10.3-0.30.10.30.3-0.5-0.4-0.3-0.30.50.7
Post-drug Anxiety0.10.10.40.1-0.3-0.2-0.30.30.20.5-0.60.10.50.6-0.40.3-0.2-0.1-0.0-0.1-0.20.0-0.0-0.1-0.00.20.00.10.4
Baseline Anxiety0.10.20.40.7-0.30.4-0.30.30.10.6-0.6-0.4-0.20.6-0.20.20.30.1-0.20.2-0.1-0.2-0.30.40.40.40.3-0.7-0.6
Tail length0.41.95.12.3-2.0-0.9-1.91.9-1.11.8-1.90.80.71.2-1.81.71.91.31.2-1.11.40.81.0-0.6-0.9-0.9-0.60.40.7
Length with tail0.41.97.72.2-2.0-0.4-1.91.90.02.8-2.70.21.92.7-1.71.31.10.10.1-0.10.2-0.3-0.30.60.20.50.5-0.80.1
Length without tail0.52.412.11.7-1.40.2-1.41.40.72.9-2.7-0.42.53.5-1.10.60.7-0.6-0.80.9-0.5-1.3-1.41.51.11.41.2-1.9-0.6
Times rat made contact with spout0.50.61.61.3-1.10.5-1.11.10.20.7-0.8-0.40.00.4-0.91.00.90.80.7-0.60.90.50.4-0.4-0.5-0.9-0.50.30.3
Lifetime Intake4.65.712.4-3.53.42.93.4-3.42.9-2.22.5-2.8-0.9-0.93.0-3.0-2.7-2.3-1.92.2-2.0-1.6-1.71.91.71.71.6-1.4-1.8
Liver weight, left0.40.72.0-1.11.41.21.4-1.40.8-1.11.0-1.2-1.4-1.20.7-0.6-0.80.10.4-0.1-0.10.10.1-0.3-0.30.2-0.10.1-0.6
Liver weight, right1.32.35.0-1.52.21.62.2-2.20.9-2.22.1-1.6-2.2-1.51.8-1.7-1.3-0.6-0.50.8-1.0-0.7-0.81.00.71.00.9-0.9-1.9
Locomotor activity0.40.72.10.10.4-0.30.4-0.4-1.1-0.50.30.4-1.5-1.1-0.10.70.91.31.3-0.91.11.21.1-0.8-1.0-1.0-0.80.7-0.1
Locomotor testing distance0.20.52.6-0.00.8-0.30.8-0.8-1.1-0.80.60.4-1.6-1.20.40.10.70.90.9-0.40.80.80.6-0.3-0.6-0.7-0.40.2-0.7
Locomotor testing rearing0.20.63.0-0.41.1-0.61.1-1.1-1.3-0.90.70.7-1.7-1.20.4-0.00.30.70.5-0.40.50.70.3-0.3-0.3-0.3-0.40.2-0.6
Locomotion in novel chamber1.21.64.9-2.22.01.82.0-2.01.4-1.71.7-1.5-0.8-1.51.8-1.7-1.0-0.8-0.40.8-0.6-0.2-0.20.20.20.10.4-0.0-0.4
Locomotion in novel chamber post-restriction0.31.03.4-1.81.60.31.5-1.50.1-1.61.3-0.1-0.8-1.80.9-0.5-0.50.10.5-0.30.30.70.7-0.7-0.7-0.9-0.71.00.5
Fecal boli incidents, locomotor time 10.10.20.8-0.5-0.4-0.8-0.20.2-0.3-0.1-0.10.80.3-0.3-0.00.0-0.5-0.2-0.3-0.2-0.10.20.3-0.3-0.1-0.1-0.30.70.9
Change in fecal boli incidents, locomotor task0.60.74.8-0.20.90.90.9-0.90.4-1.61.5-0.9-2.2-1.20.6-0.6-0.70.20.4-0.2-0.10.20.10.1-0.20.30.1-0.1-1.0
Time >=10cm from walls, locomotor time 11.11.46.2-2.51.60.11.7-1.70.8-1.61.6-0.1-0.6-1.21.5-1.5-2.2-1.2-0.70.6-1.1-0.4-0.30.30.20.80.20.3-0.1
Bouts of movement, locomotor time 14.86.210.12.8-3.0-3.2-3.13.1-3.12.1-2.43.11.20.5-2.93.02.82.32.0-2.42.32.02.0-2.1-2.0-2.3-2.12.12.7
Total resting periods, locomotor time 14.14.78.02.4-2.7-2.8-2.82.8-2.72.0-2.22.81.40.5-2.42.52.41.81.6-2.01.91.71.7-1.8-1.7-2.0-1.71.82.4
Rest time, locomotor task time 10.40.72.1-0.30.10.20.2-0.2-0.1-1.00.80.0-0.8-1.4-0.00.20.40.80.9-0.90.91.11.0-1.1-1.0-1.3-0.91.30.9
Distance moved, locomotor task time 10.20.51.6-0.70.8-0.20.8-0.80.20.3-0.2-0.10.00.60.5-0.5-1.0-0.9-0.70.8-0.9-0.8-0.80.90.71.30.7-0.9-0.8
Vertical activity count, locomotor time 10.10.62.4-1.41.60.31.5-1.50.2-0.90.8-0.4-1.2-0.70.8-0.5-0.9-0.20.00.2-0.30.10.10.1-0.00.40.0-0.0-0.5
Time >=10cm from walls, locomotor time 20.20.62.4-0.0-0.6-1.5-0.60.6-1.10.4-0.51.60.5-0.1-0.60.60.30.30.6-0.70.60.70.8-0.7-0.9-0.8-0.81.11.3
Bouts of movement, locomotor time 20.20.72.61.0-1.1-0.8-1.11.1-0.61.6-1.60.71.41.3-1.00.71.00.3-0.1-0.10.3-0.1-0.1-0.00.1-0.10.0-0.20.6
Total resting periods, locomotor time 20.10.41.40.6-0.7-0.7-0.70.7-0.61.2-1.20.71.20.9-0.70.50.70.2-0.1-0.10.2-0.1-0.1-0.10.1-0.1-0.0-0.00.5
Rest time, locomotor task time 20.71.24.2-1.61.60.71.6-1.60.4-2.01.8-0.6-1.9-2.01.0-0.6-0.80.20.2-0.3-0.10.50.3-0.6-0.3-0.3-0.40.7-0.2
Distance moved, locomotor task time 21.01.44.01.4-1.3-2.0-1.41.4-1.71.5-1.61.80.70.9-1.41.51.00.70.8-0.80.90.60.7-0.5-0.8-0.5-0.80.50.8
Vertical activity count, locomotor time 20.40.92.11.0-0.5-1.0-0.60.6-1.40.6-0.71.0-0.6-0.0-1.01.21.31.21.3-1.11.31.11.0-0.9-1.1-0.9-0.80.70.5
Light reinforcement 10.10.51.20.4-0.7-0.4-0.70.7-0.60.6-0.70.60.30.0-0.70.91.10.80.6-0.70.90.90.6-0.8-0.7-1.0-0.70.70.9
Light reinforcement 20.20.52.3-1.50.60.00.7-0.70.4-0.50.60.11.2-0.11.0-1.2-0.6-1.0-0.90.9-0.6-0.5-0.40.30.40.60.5-0.00.6
Bone: marrow area3.07.413.1-3.23.12.83.1-3.13.1-2.73.0-2.7-0.5-1.53.4-3.4-3.6-2.9-2.62.6-2.8-2.5-2.52.42.41.92.5-1.9-2.4
Bone: maximum diameter0.51.12.6-0.90.40.60.4-0.41.30.00.1-0.71.30.60.9-1.1-1.2-1.6-1.61.4-1.3-1.4-1.41.11.30.71.2-0.9-0.4
Bone: maximum force2.24.38.9-0.50.10.70.1-0.11.81.0-0.7-1.02.62.31.0-1.9-1.8-2.8-2.92.6-2.6-2.9-3.02.52.63.02.6-2.5-1.4
Bone: maximum moment2.24.19.4-0.50.10.50.1-0.11.51.1-0.7-0.82.52.31.0-1.8-1.7-2.7-2.82.6-2.6-2.9-3.02.52.63.12.6-2.5-1.4
Mean time between licks in bursts0.00.31.71.3-0.50.4-0.50.5-0.20.5-0.4-0.5-0.50.6-0.40.20.80.50.3-0.10.3-0.1-0.20.50.20.60.5-0.8-0.9
Mean num. licks in bursts0.10.20.60.4-0.10.3-0.10.1-0.1-0.0-0.1-0.2-0.6-0.3-0.40.70.50.80.6-0.70.70.60.6-0.6-0.5-0.8-0.60.50.3
Cd content in liver0.30.41.6-1.10.6-0.50.5-0.5-0.2-1.00.90.6-0.4-1.20.5-0.3-0.6-0.10.1-0.20.00.50.7-0.4-0.4-0.6-0.50.90.6
Co content in liver1.61.84.51.2-0.5-0.6-0.50.5-1.4-0.30.00.8-1.3-1.1-1.01.51.72.01.8-1.81.91.71.5-1.6-1.5-2.1-1.61.30.6
Cu content in liver0.20.20.50.2-0.1-0.1-0.20.2-0.10.2-0.30.2-0.2-0.1-0.50.70.30.60.6-0.50.60.60.5-0.5-0.6-0.7-0.70.60.5
Fe content in liver0.10.10.4-0.40.4-0.70.3-0.3-0.2-0.30.30.6-0.6-0.30.2-0.0-0.6-0.2-0.20.1-0.5-0.1-0.20.20.20.2-0.00.1-0.1
K content in liver0.80.82.1-0.00.41.00.3-0.31.30.2-0.0-1.10.10.80.4-0.3-0.6-0.9-1.20.9-1.1-1.2-1.41.11.40.41.1-1.2-1.1
Mg content in liver0.91.02.0-0.51.01.41.0-1.01.3-0.50.7-1.4-0.40.11.0-0.8-0.6-0.8-1.01.1-0.9-1.1-1.31.31.30.31.2-1.3-1.4
Mn content in liver1.11.24.50.8-1.3-1.5-1.31.3-0.61.9-1.81.21.62.1-0.80.30.3-0.7-0.90.7-0.7-0.9-0.80.70.80.90.6-0.70.4
Na content in liver0.30.30.80.4-0.5-0.6-0.50.5-0.30.5-0.50.50.90.70.0-0.20.1-0.5-0.80.5-0.5-0.7-0.80.60.80.30.6-0.7-0.3
Rb content in liver0.91.03.4-1.11.71.21.6-1.60.6-1.71.6-1.1-1.8-1.70.9-0.4-0.60.40.5-0.30.20.50.3-0.1-0.3-0.4-0.40.3-0.7
Se content in liver0.20.22.1-0.60.10.30.0-0.00.80.1-0.0-0.31.50.30.3-0.4-0.3-0.7-0.50.6-0.2-0.4-0.20.40.2-0.30.3-0.10.5
Sr content in liver1.51.34.51.5-1.7-0.8-1.71.7-0.42.1-2.00.72.12.0-1.20.91.1-0.0-0.30.00.3-0.4-0.30.10.30.00.1-0.30.7
Zn content in liver0.91.03.00.9-0.61.5-0.70.71.61.3-1.1-1.51.71.6-0.20.10.5-0.6-0.90.8-0.2-1.0-1.01.01.0-0.21.0-1.2-0.4
Bone: minimum diameter2.95.69.6-2.72.52.02.5-2.52.4-2.02.2-2.0-0.1-0.82.9-3.1-2.8-2.7-2.72.6-2.7-2.5-2.52.32.42.02.4-1.9-2.0
Time in familiar zone, hab. session 10.40.41.1-0.40.50.50.5-0.50.6-0.10.2-0.50.60.30.7-0.8-0.3-0.6-0.90.8-0.6-0.8-1.00.81.00.60.9-0.9-0.8
Time in novel zone, hab. session 10.50.54.5-0.10.5-0.10.5-0.5-0.6-1.10.90.1-2.1-1.30.10.2-0.10.70.8-0.70.30.80.7-0.8-0.6-0.2-0.70.7-0.1
Total zone transitions, hab. session 10.00.10.30.2-0.3-0.2-0.30.3-0.10.5-0.60.10.20.5-0.40.30.10.0-0.1-0.10.00.10.1-0.20.10.2-0.10.00.1
Total locomotion distance, hab. session 11.01.42.4-1.41.41.51.5-1.51.6-1.01.1-1.5-0.0-0.31.4-1.4-1.3-1.2-1.21.1-1.0-1.1-1.00.91.10.81.0-0.9-1.0
Locomotion velocity, hab. session 10.50.72.0-0.80.71.30.8-0.81.4-0.30.4-1.30.50.30.7-0.8-0.7-0.9-0.90.8-0.6-0.9-0.80.70.90.60.8-0.8-0.7
Time in familiar zone, hab. session 20.40.41.10.9-0.3-0.2-0.30.3-0.80.0-0.10.2-0.9-0.3-0.70.90.81.10.9-1.00.70.90.7-0.6-0.5-0.5-0.60.4-0.1
Time in novel zone, hab. session 20.50.61.5-0.60.20.10.2-0.20.70.00.0-0.20.70.50.7-1.0-0.7-1.1-1.11.2-0.9-1.1-1.00.81.01.00.9-0.9-0.4
Total zone transitions, hab. session 21.11.43.5-0.30.51.20.5-0.51.30.4-0.1-1.30.01.30.5-0.8-0.9-1.2-1.41.4-1.5-1.4-1.61.51.61.91.4-1.7-1.4
Total locomotion distance, hab. session 21.62.13.8-1.11.41.91.4-1.41.9-0.71.0-2.0-0.30.31.4-1.4-1.3-1.4-1.61.5-1.5-1.5-1.61.51.71.51.5-1.7-1.7
Locomotion velocity, hab. session 21.72.23.8-1.31.51.91.5-1.51.9-0.91.1-1.9-0.20.11.5-1.6-1.5-1.5-1.61.5-1.5-1.5-1.61.51.71.51.5-1.6-1.6
Novel to familiar place preference ratio0.50.64.20.1-0.7-0.5-0.80.80.41.3-1.20.42.11.6-0.40.1-0.3-0.8-0.70.7-0.3-0.8-0.60.50.30.50.5-0.50.5
Novelty place preference0.30.43.2-0.1-0.5-0.4-0.60.60.31.0-0.90.41.81.3-0.30.1-0.2-0.6-0.60.6-0.2-0.6-0.50.30.20.30.3-0.30.5
Time in novel zone, NPP test0.30.42.8-0.1-0.4-0.2-0.40.40.41.0-0.80.21.71.3-0.2-0.0-0.3-0.7-0.70.7-0.3-0.7-0.60.50.40.50.5-0.50.3
Total zone transitions, NPP test0.20.41.30.2-0.4-0.7-0.30.3-0.30.8-0.70.50.61.0-0.20.2-0.4-0.5-0.70.5-0.8-0.5-0.50.60.81.20.4-0.7-0.5
Total locomotion distance, NPP test0.60.81.4-0.91.01.11.1-1.11.1-0.60.7-1.1-0.4-0.00.9-0.8-0.9-0.8-0.90.9-1.0-0.8-0.80.91.01.00.9-1.0-1.2
Locomotion velocity, NPP test0.20.30.6-0.60.60.80.7-0.70.8-0.50.5-0.8-0.4-0.10.5-0.5-0.7-0.4-0.50.5-0.6-0.4-0.40.50.60.60.5-0.5-0.8
Intraocular pressure1.11.85.20.4-1.0-1.5-1.01.0-1.30.5-0.81.60.5-0.3-1.11.41.21.21.3-1.11.51.51.7-1.4-1.6-2.3-1.51.72.1
Delta distance traveled before/after self-admin0.91.02.11.0-0.5-0.7-0.40.4-1.40.0-0.10.7-1.1-0.7-0.81.11.31.41.4-1.21.31.21.2-0.9-1.2-1.1-1.00.80.3
Delta ambulatory time before/after self-admin0.61.02.00.8-0.3-0.8-0.30.3-1.4-0.40.30.8-1.4-1.0-0.61.00.91.41.4-1.31.11.31.2-1.1-1.2-1.0-1.10.90.2
Parametrial fat weight2.25.211.2-3.33.12.93.1-3.12.9-3.03.1-2.6-0.6-1.83.0-2.7-2.6-1.9-1.81.6-2.0-1.2-1.51.61.50.91.5-0.9-1.4
Pavlov. Cond. lever latency0.60.82.1-0.20.3-0.10.2-0.2-0.3-0.80.60.2-1.4-1.3-0.30.80.01.00.9-1.10.81.31.2-1.5-0.9-1.1-1.31.30.7
Pavlov. Cond. magazine entry latency0.91.13.7-0.3-0.00.60.0-0.01.10.7-0.5-0.71.91.30.5-0.9-0.5-1.4-1.31.3-1.1-1.5-1.41.51.30.91.5-1.3-0.6
Pavlov. Cond. change in total contacts0.30.42.3-0.3-0.4-0.5-0.30.30.00.6-0.40.51.50.80.2-0.5-0.1-0.9-0.80.7-0.5-0.8-0.60.80.50.30.7-0.40.3
Pavlov. Cond. index score0.40.52.70.4-0.8-0.5-0.70.7-0.21.1-0.90.51.61.2-0.2-0.20.4-0.6-0.40.5-0.2-0.7-0.60.80.40.40.7-0.60.1
Pavlov. Cond. latency score0.40.52.00.2-0.5-0.0-0.40.40.20.8-0.60.01.41.10.1-0.50.2-0.7-0.60.8-0.5-0.9-0.81.00.50.70.9-0.9-0.3
Pavlov. Cond. lever contacts0.60.72.1-0.00.00.30.1-0.10.50.5-0.3-0.41.00.90.5-0.9-0.3-1.0-0.91.1-0.9-1.3-1.21.40.91.11.4-1.3-0.9
Pavlov. Cond. magazine entry number0.50.63.3-0.61.10.71.1-1.10.4-1.41.3-0.7-1.8-1.20.7-0.4-0.70.10.0-0.0-0.30.1-0.1-0.20.20.3-0.20.1-0.7
Pavlov. Cond. intertrial magazine entries0.60.72.30.4-0.70.0-0.70.7-0.00.5-0.60.20.70.1-0.80.71.10.80.9-0.81.21.01.1-0.9-1.1-1.3-1.11.11.5
Pavlov. Cond. lever-magazine prob. diff.0.40.62.80.4-0.8-0.8-0.70.7-0.31.1-0.90.71.71.2-0.1-0.30.3-0.7-0.60.6-0.4-0.8-0.70.90.50.50.8-0.70.1
Pavlov. Cond. response bias0.40.53.70.4-0.8-0.3-0.70.70.01.2-1.10.31.91.3-0.3-0.10.5-0.6-0.50.5-0.1-0.6-0.50.80.30.00.7-0.60.2
Pavlov. Cond. lever latency0.40.52.1-0.00.60.60.6-0.6-0.0-1.00.8-0.5-1.5-1.10.00.40.30.81.1-0.80.70.80.8-0.6-0.9-0.9-0.70.6-0.0
Pavlov. Cond. magazine entry latency1.31.87.81.4-1.6-1.0-1.61.6-0.22.6-2.40.72.52.8-1.20.80.5-0.6-1.00.5-0.5-0.7-0.80.61.01.10.7-0.90.4
Pavlov. Cond. change in total contacts0.51.26.20.0-1.0-1.7-1.01.0-0.71.7-1.51.52.51.7-0.4-0.1-0.2-1.0-1.10.8-0.8-0.8-0.70.60.71.30.6-0.50.6
Pavlov. Cond. index score0.91.46.80.5-1.1-1.0-1.11.1-0.12.0-1.80.82.62.2-0.60.1-0.1-1.0-1.30.9-0.8-1.0-1.00.81.11.30.9-0.80.4
Pavlov. Cond. latency score0.81.26.00.2-0.9-0.8-0.90.90.21.8-1.60.52.42.1-0.4-0.1-0.3-1.2-1.41.0-0.9-1.0-1.00.91.11.30.9-0.90.3
Pavlov. Cond. lever contacts0.30.52.40.2-0.7-0.9-0.70.7-0.31.0-0.90.81.51.0-0.3-0.1-0.1-0.6-0.80.5-0.4-0.5-0.50.40.60.70.4-0.40.3
Pavlov. Cond. magazine entry number2.22.811.3-1.52.11.52.1-2.10.4-3.23.0-1.2-3.2-3.41.5-0.8-0.60.81.2-0.70.60.90.9-0.8-1.0-1.4-0.81.0-0.7
Pavlov. Cond. intertrial magazine entries0.40.82.7-0.60.6-0.30.6-0.6-0.4-1.10.90.4-1.6-1.60.10.3-0.10.70.9-1.00.60.90.9-1.1-1.1-1.2-1.11.30.7
Pavlov. Cond. lever-magazine prob. diff.1.01.67.40.7-1.3-1.3-1.31.3-0.32.2-2.01.02.72.4-0.80.20.0-1.0-1.30.8-0.8-0.9-1.00.81.01.30.8-0.80.4
Pavlov. Cond. response bias0.91.24.80.6-1.2-1.0-1.21.2-0.21.8-1.60.82.22.0-0.50.00.0-0.9-1.20.8-0.7-0.9-1.00.81.11.20.8-0.90.1
Time in closed arm before self-admin0.10.20.8-0.90.3-0.10.4-0.40.3-0.60.60.10.1-0.10.5-0.7-0.9-0.6-0.50.4-0.7-0.3-0.20.40.20.30.40.00.2
Time in closed arm after self-admin0.30.31.3-0.40.70.40.7-0.7-0.1-1.11.0-0.4-1.1-1.10.8-0.8-0.4-0.1-0.10.2-0.4-0.0-0.10.10.10.20.2-0.2-0.7
Time in open arm before self-admin0.40.53.00.70.40.40.4-0.4-0.7-0.60.4-0.4-1.7-1.00.00.30.81.10.9-0.60.80.60.4-0.5-0.4-0.4-0.6-0.1-1.1
Time in open arm after self-admin0.30.41.11.1-0.80.0-0.80.8-0.01.0-0.9-0.10.70.8-0.80.80.90.50.4-0.40.70.10.2-0.3-0.2-0.4-0.1-0.10.2
Bone: periosteal estimation1.74.06.9-1.91.61.91.6-1.62.4-1.01.2-1.90.80.12.2-2.5-2.4-2.6-2.52.4-2.3-2.4-2.42.22.21.82.3-1.9-1.6
Bone: periosteal perimeter0.91.83.3-1.31.01.21.0-1.01.7-0.50.7-1.20.50.21.3-1.5-1.7-1.8-1.81.5-1.8-1.7-1.71.31.61.31.5-1.2-0.9
Bone: post-yield work3.76.412.4-2.82.01.22.0-2.02.2-1.51.8-1.40.9-0.22.8-3.1-3.5-3.4-3.42.9-3.5-3.0-3.12.62.92.82.7-2.1-1.9
Progressive ratio test 1 active lever presses0.61.12.4-1.51.41.41.3-1.31.5-1.21.4-1.4-0.7-0.81.2-1.3-1.4-0.9-0.70.7-0.8-0.5-0.50.50.50.70.5-0.2-0.6
Progressive ratio test 1 breakpoint0.61.02.2-1.41.41.31.3-1.31.5-1.21.4-1.3-0.7-0.81.2-1.2-1.5-0.9-0.70.6-0.8-0.4-0.40.50.50.70.4-0.2-0.5
Progressive ratio test 1 inactive lever presses0.20.51.2-0.30.10.50.1-0.10.70.4-0.4-0.61.10.80.4-0.6-0.3-0.8-0.90.9-0.6-0.8-0.91.10.90.70.9-0.8-0.3
Progressive ratio test 2 active lever presses1.52.25.9-2.42.01.81.9-1.91.8-1.81.9-1.7-0.3-1.02.0-2.2-1.6-1.5-1.31.3-1.2-0.8-0.90.90.90.70.7-0.3-0.4
Progressive ratio test 2 breakpoint1.72.25.7-2.42.01.81.9-1.91.9-1.71.9-1.7-0.2-0.92.0-2.2-1.6-1.5-1.31.3-1.2-0.9-0.90.91.00.70.7-0.4-0.4
Progressive ratio test 2 inactive lever presses0.92.89.2-3.02.52.62.5-2.52.4-1.51.6-2.30.0-0.72.1-2.1-1.3-1.4-1.21.4-0.9-0.8-0.81.10.90.20.8-0.4-0.1
Incentive Sensitization - Responses0.51.43.4-1.20.70.50.8-0.80.90.00.1-0.51.40.91.1-1.4-0.8-1.7-1.81.6-1.4-1.4-1.51.51.61.21.3-1.2-0.4
Incentive Sensitization - Breakpoint0.61.43.3-1.30.80.70.9-0.91.0-0.20.2-0.71.30.81.2-1.5-0.8-1.7-1.81.6-1.4-1.4-1.41.51.61.11.3-1.1-0.4
Sum of active levers in priming session hrs 5-63.02.86.71.3-2.2-2.6-2.22.2-2.01.8-1.92.51.81.1-1.91.71.50.80.9-1.21.11.01.2-1.2-1.2-1.3-1.01.52.5
Progressive ratio0.41.13.0-1.00.6-0.20.6-0.60.5-0.20.40.00.00.41.0-1.2-1.6-1.6-1.31.2-1.7-1.2-1.11.31.11.71.2-0.9-0.9
Food seeking constrained by brief footshock0.00.00.20.20.1-0.00.1-0.1-0.2-0.40.3-0.0-0.4-0.10.1-0.0-0.1-0.0-0.1-0.0-0.3-0.0-0.20.30.20.20.2-0.2-0.4
Seeking ratio, punishment vs. effort0.20.41.80.70.01.30.0-0.00.3-0.40.4-1.1-0.5-0.5-0.20.41.11.10.7-0.51.00.60.4-0.4-0.4-1.1-0.50.1-0.2
Retroperitoneal fat weight2.410.527.0-4.85.24.75.2-5.23.7-4.94.8-4.1-2.8-3.94.1-3.5-2.7-1.1-0.81.4-1.1-0.5-0.80.80.7-0.10.8-0.4-2.0
Reaction time number correct0.10.41.61.0-0.90.2-1.01.00.31.3-1.2-0.30.41.0-1.00.60.70.50.5-0.30.60.20.4-0.2-0.4-0.1-0.2-0.00.4
Reaction time mean minus median0.21.68.50.6-1.4-2.9-1.41.4-2.01.4-1.42.61.21.0-1.41.00.20.10.1-0.70.20.50.5-0.7-0.40.6-0.80.91.5
Reaction time mean minus median AUC0.31.75.91.0-1.4-2.4-1.41.4-1.91.3-1.42.20.50.6-1.61.40.70.80.6-1.20.80.90.9-1.3-0.8-0.3-1.31.21.5
Reaction time num false alarms0.30.52.40.70.10.20.1-0.1-0.7-0.40.2-0.1-1.6-0.9-0.30.50.91.21.1-0.81.00.80.6-0.6-0.8-0.9-0.60.3-0.5
Reaction time num false alarms AUC0.20.61.51.2-0.4-0.2-0.40.4-0.90.3-0.40.2-1.1-0.3-0.70.91.21.21.1-0.91.10.80.5-0.6-0.7-0.8-0.70.2-0.3
Reaction time trials correct on left0.10.41.61.0-0.90.2-1.01.00.31.3-1.2-0.30.41.0-1.00.60.70.50.5-0.30.60.20.4-0.2-0.4-0.1-0.2-0.00.4
Reaction time trials on left0.20.51.81.1-1.00.1-1.01.00.21.3-1.3-0.20.41.0-1.10.70.80.60.6-0.40.60.20.5-0.3-0.4-0.1-0.30.00.4
Reaction time mean0.10.31.1-0.3-0.2-0.9-0.10.1-0.60.2-0.30.9-0.0-0.1-0.50.5-0.10.20.2-0.60.30.60.6-0.8-0.4-0.0-0.80.91.1
Reaction time mean AUC0.10.31.0-0.4-0.1-0.9-0.00.0-0.50.2-0.20.8-0.1-0.1-0.40.4-0.20.10.1-0.50.20.50.6-0.8-0.4-0.1-0.80.91.0
Median of all reaction times0.10.10.5-0.70.30.30.4-0.40.5-0.10.1-0.3-0.1-0.10.1-0.0-0.4-0.1-0.1-0.0-0.10.10.2-0.4-0.00.0-0.40.40.5
Reaction time omissions0.71.13.61.0-1.3-1.9-1.21.2-1.61.1-1.21.80.10.6-1.31.40.60.70.7-1.00.50.80.9-1.0-0.7-0.1-1.00.91.0
Reaction time false alarm rate0.20.31.70.30.4-0.10.4-0.4-0.8-0.60.50.1-1.3-0.90.20.20.50.60.6-0.40.50.50.2-0.2-0.3-0.4-0.30.1-0.7
Reaction time premature initiation rate1.32.06.61.6-1.01.2-0.90.91.11.6-1.3-1.31.72.6-0.2-0.30.7-0.8-1.01.3-0.6-1.7-1.51.81.41.31.8-2.4-1.6
Reaction time premature initiations0.72.29.02.5-2.00.8-1.91.90.72.6-2.3-1.01.83.0-1.20.61.4-0.0-0.30.70.1-1.1-0.71.10.70.71.1-1.8-0.8
Std. dev. reaction times0.51.76.80.5-1.0-2.6-0.90.9-2.20.6-0.82.5-0.0-0.1-1.31.30.50.80.8-1.40.81.31.3-1.5-1.1-0.3-1.61.71.7
Reaction time trials completed0.20.51.81.1-1.00.1-1.01.00.21.3-1.3-0.20.41.0-1.10.70.80.60.6-0.40.60.20.5-0.3-0.4-0.1-0.30.00.4
Reaction time trials AUC0.10.31.30.9-0.80.3-0.80.80.31.2-1.1-0.40.30.9-0.80.50.60.50.4-0.20.50.10.3-0.2-0.3-0.1-0.2-0.10.2
Run reversals in cocaine runway, females2.02.35.6-0.40.91.70.9-0.91.6-0.40.6-1.90.10.51.4-1.7-1.0-1.4-1.61.8-1.7-1.8-2.01.71.91.81.9-2.2-2.4
Run reversals in cocaine runway, males0.30.31.0-0.00.1-0.30.1-0.1-0.4-0.50.40.3-1.0-0.7-0.20.4-0.00.60.7-0.70.50.70.6-0.7-0.7-0.4-0.70.70.3
Latency to leave start box in cocaine runway1.01.33.6-1.21.21.91.1-1.11.9-1.21.3-1.8-0.3-0.81.4-1.6-1.4-1.1-1.01.0-0.9-0.8-0.80.80.80.80.8-0.6-0.9
Latency to leave start box in cocaine runway, F0.20.31.2-0.40.41.10.3-0.31.0-0.10.2-1.00.50.10.5-0.6-0.4-0.5-0.60.6-0.3-0.5-0.50.50.60.30.6-0.5-0.4
Latency to leave start box in cocaine runway, M1.11.03.3-1.11.10.91.1-1.10.9-1.81.8-0.9-1.3-1.61.3-1.3-1.5-0.7-0.30.4-0.8-0.3-0.30.30.20.70.3-0.0-0.8
Std. dev. time between licks in bursts0.10.21.30.9-0.10.1-0.10.1-0.6-0.30.3-0.2-1.1-0.2-0.10.10.70.60.3-0.20.30.1-0.10.10.20.40.1-0.3-0.8
Total sessions with >9 infusions0.91.12.8-1.61.70.81.6-1.60.9-1.31.3-0.8-1.1-0.81.3-1.1-1.6-0.9-0.50.6-0.8-0.4-0.50.60.50.90.4-0.3-0.9
Short access day 1 total inactive lever presses1.01.97.0-1.92.02.62.0-2.02.3-0.91.0-2.4-0.0-0.41.6-1.5-0.9-1.0-0.71.3-0.5-0.8-0.81.10.70.40.9-1.0-1.1
Short access day 10 total inactive lever presses0.10.30.90.00.10.20.1-0.1-0.2-0.70.6-0.0-0.9-1.00.00.20.50.70.8-0.60.70.70.8-0.5-0.8-0.9-0.70.70.3
Short access day 1 total infusions1.32.66.3-2.42.52.52.5-2.52.3-1.92.0-2.3-1.3-1.21.9-1.7-1.8-1.0-0.61.0-0.8-0.4-0.60.80.50.70.6-0.5-1.2
Short access day 10 total infusions2.94.810.2-3.23.12.13.1-3.12.4-1.82.1-2.1-0.7-0.52.6-2.4-2.7-2.3-1.92.1-2.1-1.6-1.72.01.71.91.7-1.5-1.9
Short access total infusions2.84.09.1-2.83.02.03.0-3.02.2-1.92.1-2.1-1.3-0.82.4-2.1-2.5-1.7-1.41.6-1.7-1.2-1.41.61.41.81.3-1.3-2.0
Short access day 1 locomotion1.11.85.1-1.81.72.31.7-1.72.1-1.11.2-2.1-0.1-0.51.6-1.6-1.4-1.2-0.91.2-0.9-0.9-0.90.90.80.70.9-0.7-0.9
Short access day 10 total locomotion0.83.49.2-2.01.72.91.8-1.83.0-1.01.3-2.80.60.12.0-2.2-1.8-2.0-1.82.0-1.7-1.7-1.51.81.71.41.7-1.5-1.3
Short access total locomotion2.33.48.0-2.42.22.82.2-2.22.8-1.31.6-2.60.2-0.32.2-2.2-1.9-1.9-1.71.9-1.6-1.5-1.51.51.51.21.5-1.3-1.3
One hour access (0.3 mA shock)2.83.37.7-2.82.52.62.5-2.52.3-1.92.1-2.4-0.3-0.92.5-2.6-1.5-1.7-1.51.7-1.3-1.2-1.21.21.20.71.1-0.9-0.9
Compulsive drug intake1.62.49.33.1-2.6-1.1-2.62.6-1.41.7-1.81.10.61.0-1.91.72.11.51.0-1.11.20.80.8-0.6-0.6-0.8-0.70.20.5
One hour access (shock baseline)1.64.213.2-3.63.12.13.1-3.12.0-2.93.0-1.9-1.0-1.92.8-2.8-2.2-1.7-1.21.4-1.4-0.8-0.90.70.80.50.8-0.1-0.6
Social response proportion0.10.10.50.6-0.7-0.5-0.60.6-0.30.5-0.50.50.30.3-0.30.40.10.00.10.0-0.1-0.10.1-0.0-0.0-0.10.0-0.10.0
Social responses0.70.92.01.3-1.2-1.4-1.11.1-1.41.1-1.11.30.30.4-1.21.31.10.90.9-0.90.80.70.8-0.8-0.8-0.6-0.50.50.6
Social time0.50.71.80.8-0.7-1.1-0.70.7-1.20.7-0.81.1-0.70.0-1.01.30.70.90.9-1.00.70.90.7-0.9-0.8-0.5-0.80.70.5
Soleus weight0.82.49.4-2.02.30.52.3-2.3-0.4-2.92.7-0.3-2.7-3.11.5-1.2-0.50.60.9-0.40.50.80.8-0.9-0.9-0.6-0.80.9-0.3
Bone: stiffness0.50.92.4-0.2-0.30.3-0.30.31.20.7-0.6-0.41.61.20.2-0.5-1.2-1.4-1.31.0-1.3-1.3-1.30.91.01.11.0-0.8-0.2
Tibialis anterior weight2.48.434.63.6-4.1-2.1-4.14.1-0.55.4-5.01.65.15.9-2.81.81.4-1.0-1.30.9-0.5-1.5-1.41.61.31.71.4-1.90.5
Time to tail flick, vehicle, before self-admin1.11.43.0-1.00.90.80.8-0.81.2-0.40.6-0.90.30.41.2-1.4-1.5-1.6-1.41.4-1.7-1.4-1.31.41.31.61.4-1.2-1.0
Time to tail flick, vehicle, after self-admin0.71.43.7-0.60.90.20.8-0.80.6-0.20.4-0.4-0.10.51.0-1.1-1.6-1.4-1.41.3-1.7-1.4-1.51.21.51.91.3-1.5-1.6
Time to tail flick, test, before self-admin3.54.07.4-1.82.02.72.2-2.22.5-0.91.1-2.70.20.52.1-2.3-1.6-1.9-1.92.3-1.8-2.1-2.12.12.11.82.3-2.3-2.3
Time to tail flick, test, after self-admin0.20.21.20.1-0.4-1.1-0.40.4-0.70.5-0.61.10.90.2-0.40.5-0.1-0.00.0-0.20.20.20.2-0.1-0.2-0.2-0.10.40.6
Delta time to tail flick, vehicle, before/after SA0.10.10.30.3-0.1-0.3-0.00.0-0.20.3-0.30.2-0.10.3-0.10.2-0.3-0.1-0.20.2-0.2-0.2-0.30.10.30.50.2-0.4-0.6
Delta time to tail flick, test, before/after SA4.05.08.02.2-2.7-2.8-2.82.8-2.51.7-2.02.80.90.1-2.52.62.01.91.9-2.32.22.02.1-2.0-2.1-2.2-2.12.32.7
Tibia length0.51.49.00.5-1.5-0.8-1.51.50.21.9-1.80.73.02.1-0.6-0.00.2-1.1-1.10.8-0.6-1.1-0.90.70.60.50.6-0.51.0
Ambulatory time before self-admin0.20.73.8-0.3-0.5-0.4-0.40.40.41.2-1.00.41.91.7-0.2-0.2-0.4-1.1-1.00.9-0.7-1.0-0.80.70.80.71.1-0.70.4
Ambulatory time after self-admin0.00.10.7-0.2-0.2-0.0-0.10.10.20.3-0.20.10.80.5-0.1-0.10.1-0.2-0.20.20.1-0.1-0.00.10.0-0.20.4-0.00.4
Bone: tissue strength0.20.21.4-0.0-0.1-1.2-0.10.1-1.20.1-0.21.1-0.4-0.2-0.30.30.30.40.4-0.30.30.40.4-0.4-0.40.2-0.50.50.4
Total heroin consumption2.73.29.22.1-2.3-3.0-2.32.3-2.42.7-2.52.72.52.6-2.32.11.60.60.4-0.60.60.20.3-0.4-0.3-0.1-0.30.01.2
Bone: trabecular number0.81.63.5-0.70.3-0.10.3-0.30.90.5-0.3-0.11.51.30.8-1.1-1.3-1.9-1.91.9-1.6-1.8-1.41.71.61.51.6-1.4-0.7
Bone: trabecular spacing0.71.12.60.7-0.20.5-0.20.2-0.4-0.1-0.0-0.4-1.5-0.8-0.81.21.11.61.6-1.41.31.41.2-1.2-1.3-1.3-1.31.00.4
Bone: trabecular thickness0.30.41.2-1.11.0-0.11.0-1.00.2-0.70.70.1-0.0-0.40.8-0.9-0.9-0.6-0.40.5-0.6-0.4-0.20.30.20.70.4-0.2-0.2
Bone: trabecular tissue density2.13.69.2-0.80.7-1.50.7-0.7-2.1-1.91.41.6-2.6-3.0-0.30.90.52.02.3-2.11.62.62.4-2.4-2.5-1.8-2.62.81.5
Water consumed over 24 hours0.51.03.71.9-1.7-0.2-1.71.7-0.21.4-1.40.21.21.1-1.20.91.30.70.6-0.51.00.40.4-0.2-0.5-0.7-0.30.10.5
Number of responses in last shaping day0.10.20.70.7-0.3-0.3-0.40.4-0.50.7-0.80.30.50.4-0.20.30.90.20.20.10.4-0.1-0.10.1-0.0-0.20.2-0.4-0.3