Plaat3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC mRNA stability Plaat3 0.17 0.1 4.2e-03 0.05 0.01 0.04 -0.01 3.1e-02 1.8e-01 3.2e-02 7.5e-01
2 NAcc mRNA stability Plaat3 0.03 0.02 6.4e-04 0.02 0.01 0.02 0.01 1.8e-04 2.4e-03 2.5e-04 1.9e-03
3 pVTA alternative TSS XM_039101108.2 0.03 0.02 4.1e-03 0.02 0.03 0.04 0.02 1.4e-02 2.3e-03 5.3e-04 5.9e-03
4 Liver intron excision ratio chr1_214212364_214230191 0.07 0.04 1.5e-05 0.05 0.04 0.04 0.05 5.5e-06 9.1e-05 2.6e-05 7.0e-06
5 Liver intron excision ratio chr1_214230293_214237794 0.05 0.03 1.5e-04 0.04 0.03 0.03 0.04 4.3e-05 6.5e-04 1.9e-04 6.6e-05
6 pVTA alternative TSS XM_039101108.2 0.03 0.02 5.8e-03 0.01 0.02 0.04 0.01 5.9e-02 5.7e-03 2.3e-04 2.7e-02
7 pVTA mRNA stability Plaat3 0.1 0.05 2.1e-06 0.04 0.07 0.06 0.07 1.7e-04 3.2e-06 3.2e-05 1.2e-06
8 Brain mRNA stability Plaat3 0.14 0.08 3.9e-09 0.09 0.08 0.1 0 7.2e-09 5.3e-08 2.0e-09 1.2e-01
9 pVTA alternative TSS NM_017060.2 0.03 0.02 6.2e-03 0.02 0.03 0.04 0.02 1.4e-02 3.4e-03 4.8e-04 7.0e-03
10 IL mRNA stability Plaat3 0.36 0.14 1.8e-05 0.16 0.11 0.22 0.03 1.1e-04 1.2e-03 6.8e-06 6.2e-02
11 Adipose gene expression Plaat3 0.33 0.11 0.0e+00 0.19 0.18 0.18 0.19 1.1e-20 4.7e-20 4.5e-20 1.5e-20
12 NAcc isoform ratio XM_039101108.2 0.04 0.02 1.9e-07 0.04 0.04 0.04 0.04 1.0e-06 2.7e-07 2.7e-07 4.1e-07
13 Brain isoform ratio XM_039101108.2 0.02 0.02 5.2e-03 0.01 0.02 0.03 0.02 1.5e-02 2.5e-03 1.2e-03 9.5e-03
14 PL mRNA stability Plaat3 0.06 0.04 5.9e-07 0.02 0.04 0.04 0.03 1.5e-03 3.5e-05 3.0e-05 1.1e-04
15 RMTg gene expression Plaat3 0.27 0.11 8.9e-07 0.21 0.23 0.2 0.23 2.9e-06 8.4e-07 4.4e-06 9.1e-07
16 pVTA gene expression Plaat3 0.5 0.12 0.0e+00 0.52 0.53 0.53 0.53 1.6e-48 1.9e-49 3.3e-49 1.2e-49
17 Liver gene expression Plaat3 0.36 0.14 0.0e+00 0.21 0.26 0.26 0.24 8.1e-23 3.6e-28 3.9e-28 5.9e-27
18 Brain gene expression Plaat3 0.32 0.1 0.0e+00 0.33 0.34 0.36 0.36 1.2e-31 3.7e-33 1.4e-34 5.2e-35
19 NAcc gene expression Plaat3 0.31 0.09 0.0e+00 0.39 0.39 0.39 0.4 3.4e-63 5.3e-63 4.8e-63 2.3e-64
20 PL isoform ratio XM_039101108.2 0.03 0.02 1.6e-03 0.02 0.02 0.02 0.01 2.9e-03 6.4e-03 5.2e-03 2.0e-02
21 LHb gene expression Plaat3 0.53 0.14 2.5e-08 0.32 0.28 0.3 0.3 1.7e-08 2.5e-07 9.4e-08 8.9e-08
22 pVTA isoform ratio NM_017060.2 0.04 0.03 8.8e-03 0.02 0.02 0.02 0.01 9.4e-03 1.1e-02 1.0e-02 1.9e-02
23 BLA gene expression Plaat3 0.1 0.05 4.1e-05 0.09 0.06 0.06 0.07 1.3e-05 5.7e-04 4.8e-04 1.7e-04
24 Adipose mRNA stability Plaat3 0.14 0.09 2.6e-09 0.07 0.07 0.06 0.06 4.4e-08 8.2e-08 6.2e-07 3.0e-07
25 PL gene expression Plaat3 0.08 0.04 3.4e-07 0.06 0.06 0.06 0.06 9.7e-07 5.5e-07 7.2e-07 8.7e-07
26 NAcc isoform ratio NM_017060.2 0.02 0.01 2.8e-03 0 0.01 -0 0 3.8e-01 8.1e-03 6.2e-01 7.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.71.22.40.7-0.6-0.0-0.60.6-0.7-0.1-0.20.2-0.7-0.60.91.11.4-1.6-1.51.4-1.5-1.51.3-1.4-1.4-1.3-1.4-1.2-1.0
Area under the delay curve0.60.71.30.4-0.7-1.1-0.70.7-1.1-0.5-0.61.20.4-0.10.80.80.8-0.7-0.80.8-1.0-0.91.0-0.9-0.9-0.9-0.9-1.0-1.1
BMI with tail3.913.322.61.8-1.8-3.0-1.81.8-4.30.5-0.03.2-2.8-2.82.63.33.7-4.5-4.64.5-4.5-4.74.7-4.6-4.6-4.7-4.6-4.7-3.8
BMI without tail0.82.35.00.3-0.7-0.9-0.70.7-1.40.20.11.0-0.8-1.11.11.21.4-1.8-1.81.8-1.8-2.02.0-2.0-2.0-2.1-2.2-2.2-2.2
Body weight1.88.016.0-0.0-0.1-1.8-0.10.1-3.12.21.82.1-3.4-3.90.81.52.0-3.3-3.33.3-3.2-3.73.7-3.8-3.5-3.7-3.8-4.0-2.7
Weight adjusted by age0.40.62.5-1.11.30.31.3-1.30.01.00.8-0.2-1.6-1.3-0.4-0.1-0.5-0.5-0.50.5-0.4-0.70.6-0.7-0.5-0.2-0.7-0.60.1
Bone surface1.22.36.1-0.00.60.40.6-0.6-1.01.31.1-0.1-2.5-2.10.30.71.5-2.2-2.31.8-1.9-2.21.8-1.8-2.0-1.4-1.8-1.6-0.6
Bone volume0.91.64.20.7-0.10.3-0.00.0-1.00.60.4-0.1-1.8-1.30.71.01.6-2.1-2.01.7-1.7-1.91.5-1.5-1.6-1.2-1.5-1.3-0.5
Breakpoint value in progressive ratio session1.31.55.8-1.31.52.41.7-1.71.71.81.7-2.1-1.5-1.7-1.5-1.4-0.70.20.2-0.40.10.1-0.20.50.2-0.20.10.20.9
Number of licking bursts0.00.00.2-0.30.50.00.5-0.5-0.20.30.2-0.0-0.4-0.3-0.10.0-0.1-0.2-0.00.1-0.1-0.10.1-0.2-0.0-0.0-0.1-0.10.0
Context. condit. distance diff. score0.70.81.81.1-1.3-0.3-1.31.3-0.2-1.2-1.30.20.61.01.31.20.8-0.6-0.70.8-0.4-0.60.8-0.8-0.8-0.4-0.7-0.6-1.1
Locomotion velocity, session 10.30.31.20.4-0.8-0.2-0.70.7-0.0-0.5-0.60.31.10.30.50.40.6-0.2-0.30.4-0.5-0.20.3-0.4-0.5-0.9-0.3-0.5-0.9
Locomotion distance, session 11.11.43.80.8-1.1-0.8-1.01.0-0.9-0.3-0.61.00.5-0.41.01.11.3-1.2-1.31.4-1.5-1.31.4-1.3-1.5-2.0-1.2-1.4-1.5
Locomotion velocity, session 20.70.82.9-0.40.4-0.10.5-0.5-0.61.20.90.3-1.0-1.7-0.20.30.4-0.9-1.00.8-1.0-1.01.0-1.2-1.2-1.7-1.1-1.2-0.6
Locomotion distance, session 20.20.31.50.0-0.5-0.4-0.50.5-0.3-0.0-0.20.60.9-0.30.10.10.4-0.3-0.50.3-0.7-0.40.5-0.5-0.8-1.2-0.4-0.6-0.8
Locomotion velocity, session 34.65.28.92.1-2.5-2.7-2.42.4-3.0-1.0-1.42.70.2-0.52.32.42.3-2.3-2.52.7-2.6-2.52.6-2.2-2.6-2.2-2.2-2.5-2.3
Locomotion distance, session 30.40.40.80.4-0.7-0.7-0.70.7-0.7-0.1-0.30.70.2-0.30.50.60.4-0.5-0.70.7-0.7-0.70.7-0.7-0.8-0.8-0.6-0.9-0.9
Stereotopy head waving bouts, day 33.54.05.82.0-2.3-2.1-2.32.3-2.2-1.7-1.92.10.70.52.32.42.3-1.9-1.92.0-2.1-1.92.0-1.9-2.0-1.9-2.1-1.8-2.2
Stereotopy head waving duration, day 31.01.22.11.4-1.4-1.0-1.51.5-1.1-1.1-1.20.90.50.51.41.31.3-1.0-1.01.2-1.1-0.91.0-1.0-1.0-0.7-1.1-0.8-1.0
Locomotion velocity, session 71.51.72.71.6-1.6-1.3-1.61.6-1.4-0.9-1.11.30.50.21.41.41.5-1.2-1.51.3-1.5-1.21.2-0.9-1.5-1.5-1.1-1.1-1.2
Locomotion distance, session 70.91.12.60.6-1.0-1.3-1.11.1-1.1-0.8-1.01.40.50.31.21.01.0-0.8-1.11.0-1.1-1.11.1-1.1-1.3-1.0-1.2-1.2-1.6
Stereotopy head waving bouts, day 70.20.30.91.0-0.50.1-0.50.5-0.60.10.1-0.1-0.5-0.40.40.51.0-0.8-0.70.6-0.8-0.40.5-0.3-0.5-0.7-0.2-0.10.2
Stereotopy head waving duration, day 70.40.42.10.10.40.90.4-0.4-0.01.21.2-0.7-1.1-1.4-0.4-0.10.4-0.7-0.60.6-0.6-0.40.4-0.4-0.5-0.9-0.2-0.30.5
Locomotion velocity, session 80.30.33.1-0.40.10.90.1-0.11.0-0.2-0.2-0.71.80.4-0.4-0.70.30.50.4-0.6-0.00.6-0.30.30.2-0.50.60.4-0.3
Locomotion distance, session 81.21.83.21.7-1.8-0.3-1.81.8-0.5-1.4-1.60.41.10.91.71.51.8-1.2-1.31.2-1.3-1.01.2-1.2-1.4-1.5-1.0-0.9-1.5
Degree of sensitization distance1.51.53.00.9-1.0-1.3-1.01.0-1.3-0.8-1.01.3-0.20.21.41.41.3-1.4-1.41.4-1.3-1.41.4-1.6-1.4-1.1-1.7-1.4-1.5
Degree of sensitization stereotypy0.30.31.20.30.30.70.3-0.3-0.20.90.8-0.6-1.1-1.1-0.3-0.00.5-0.6-0.60.4-0.5-0.30.3-0.1-0.3-0.7-0.0-0.00.6
Conditioned locomotion0.20.20.7-0.50.4-0.30.4-0.4-0.40.60.50.4-0.2-0.8-0.3-0.20.1-0.3-0.20.2-0.3-0.30.2-0.6-0.4-0.6-0.6-0.5-0.4
Cocaine response after cond. corrected1.01.23.61.1-1.6-1.9-1.61.6-1.4-1.3-1.41.81.41.21.20.90.9-0.2-0.30.5-0.4-0.40.4-0.2-0.4-0.3-0.3-0.5-1.3
Cocaine response after cond. not corrected0.60.71.71.0-1.3-1.2-1.31.3-0.9-1.0-1.11.11.00.91.00.80.8-0.3-0.40.5-0.5-0.50.4-0.2-0.5-0.3-0.3-0.5-1.1
Cocaine response before conditioning0.91.14.7-0.81.32.21.3-1.31.71.31.3-2.0-1.2-0.9-1.0-0.9-0.80.2-0.1-0.40.30.1-0.20.40.10.20.40.51.1
Saline control response1.21.65.1-1.82.00.92.0-2.00.42.22.0-0.6-2.0-2.3-1.2-0.8-0.9-0.1-0.70.3-0.0-0.70.8-0.6-0.8-0.6-0.5-0.9-0.2
Bone: connectivity density1.11.73.60.00.20.20.2-0.2-0.80.80.60.1-1.8-1.70.50.81.2-1.8-1.91.7-1.6-1.91.6-1.8-1.8-1.3-1.7-1.7-1.0
Bone: cortical apparent density1.11.42.7-1.31.41.21.4-1.41.40.91.1-1.2-0.6-0.5-1.3-1.1-1.61.21.4-1.11.41.2-1.31.11.40.91.00.91.2
Bone: cortical area0.50.71.9-0.30.5-0.10.5-0.5-0.51.00.80.2-1.4-1.40.10.50.1-1.0-1.21.0-0.8-1.21.2-0.8-1.1-0.9-1.0-1.0-0.2
Bone: cortical porosity0.91.03.0-0.50.51.70.5-0.51.70.40.5-1.60.80.3-1.0-1.1-0.61.00.9-1.20.71.1-1.11.00.90.31.21.10.9
Bone: cortical porosity0.80.83.0-0.60.71.70.7-0.71.60.60.7-1.60.80.0-1.0-1.1-0.50.80.7-1.00.40.9-0.90.90.7-0.01.00.90.8
Bone: cortical thickness1.72.98.0-2.82.61.12.6-2.61.22.82.8-1.0-1.5-2.5-2.2-1.8-2.41.00.7-0.81.10.4-0.30.60.40.10.5-0.10.8
Bone: cortical thickness0.20.31.3-1.10.6-0.50.6-0.60.10.70.60.50.4-0.6-0.7-0.7-0.90.60.3-0.40.30.10.00.40.00.10.1-0.3-0.4
Bone: cortical tissue density1.21.73.0-1.51.51.21.5-1.51.41.11.2-1.3-0.6-0.6-1.5-1.2-1.71.31.5-1.21.41.2-1.41.21.51.01.00.91.2
Condit. Reinf. active minus inactive responses0.40.42.2-0.30.4-1.40.5-0.5-1.50.90.81.3-0.6-1.2-0.3-0.2-0.3-0.3-0.40.4-0.1-0.40.4-0.4-0.50.2-0.4-0.50.1
Condit. Reinf. active-inactive response ratio0.40.51.0-0.70.8-0.50.9-0.9-0.40.80.90.4-0.3-0.6-0.8-1.0-0.90.60.5-0.50.80.5-0.50.50.51.00.60.50.8
Condit. Reinf. active responses0.70.84.20.3-0.1-1.8-0.00.0-2.00.50.41.7-0.8-1.10.30.60.2-0.9-0.90.9-0.7-0.90.8-1.0-0.8-0.3-1.0-0.9-0.2
Condit. Reinf. inactive responses1.01.22.21.3-1.2-1.1-1.11.1-1.4-0.6-0.71.1-0.1-0.11.21.51.2-1.3-1.11.1-1.5-1.10.9-1.2-0.9-1.1-1.3-0.9-0.7
Incentive salience index mean0.81.03.2-0.00.1-1.60.1-0.1-1.80.70.61.6-1.0-1.40.20.50.2-1.0-1.01.1-0.8-1.21.1-1.1-1.1-0.6-1.2-1.2-0.6
Condit. Reinf. lever presses0.81.12.10.4-0.0-0.8-0.10.1-1.20.70.50.8-1.3-1.30.50.80.5-1.3-1.41.5-1.3-1.51.4-1.4-1.4-1.0-1.4-1.4-0.7
Condit. Reinf. active minus inactive responses0.10.10.60.8-0.10.7-0.10.10.2-0.10.0-0.7-0.30.2-0.00.00.4-0.1-0.3-0.10.00.2-0.10.50.10.30.50.60.7
Condit. Reinf. active-inactive response ratio0.70.84.72.2-1.3-0.9-1.31.3-1.5-0.8-0.80.8-0.30.51.00.91.5-1.0-0.70.6-0.7-0.30.2-0.1-0.30.1-0.20.30.4
Condit. Reinf. active responses0.10.10.4-0.10.50.60.5-0.50.30.50.6-0.6-0.5-0.5-0.3-0.2-0.1-0.0-0.3-0.00.1-0.10.20.1-0.10.00.20.10.4
Condit. Reinf. inactive responses0.50.72.7-1.71.21.31.2-1.21.50.90.8-1.20.1-0.5-0.9-0.8-1.10.80.2-0.50.40.20.00.2-0.0-0.10.3-0.1-0.1
Condit. Reinf. lever presses0.50.72.8-0.20.80.80.9-0.9-0.01.21.1-0.6-1.7-1.4-0.20.20.3-0.9-1.20.8-0.7-0.91.0-0.7-0.9-0.9-0.7-0.70.1
Condit. Reinf. lever reinforcers received0.20.30.7-0.30.80.80.8-0.80.40.80.8-0.8-0.7-0.7-0.6-0.3-0.30.0-0.3-0.10.1-0.00.10.2-0.10.10.30.10.6
Conditioned reinforcement - actives0.10.21.30.8-0.21.1-0.20.20.7-0.1-0.1-1.0-0.30.30.10.20.4-0.4-0.1-0.1-0.00.2-0.30.10.20.10.30.81.0
Conditioned reinforcement - inactives0.60.92.71.6-1.1-1.3-1.11.1-1.4-0.7-0.71.1-0.40.21.21.30.8-1.1-1.01.0-0.7-0.70.6-1.0-0.7-0.2-0.6-0.20.2
Conditioned locomotion1.62.15.92.2-2.1-2.4-2.12.1-1.6-2.2-2.12.11.01.92.11.90.6-0.6-0.40.8-0.1-0.20.2-0.5-0.20.5-0.30.0-0.5
Patch foraging indifference point 0 sec0.20.31.7-0.00.1-0.20.1-0.1-0.30.70.70.2-1.3-0.70.10.0-0.4-0.5-0.60.7-0.2-0.60.6-0.7-0.60.2-0.6-0.7-0.2
Patch foraging indifference point AUC0.91.33.6-1.31.81.41.8-1.80.71.81.7-1.3-1.9-1.6-1.4-0.9-0.60.10.0-0.50.20.0-0.20.40.2-0.00.30.41.3
Delay disc. indifference point, 0s delay1.82.03.21.4-1.7-1.7-1.81.8-1.6-1.6-1.71.71.60.61.51.51.8-1.0-0.81.0-1.4-1.01.2-1.1-0.9-1.6-1.2-1.0-1.7
Delay disc. indifference point, 16s delay0.60.72.30.5-0.5-1.4-0.40.4-1.5-0.1-0.21.3-0.7-0.30.70.90.4-0.8-1.10.9-0.8-0.90.8-0.7-1.0-0.3-0.9-0.8-0.4
Delay disc. indifference point, 2s delay1.01.12.01.2-1.0-1.1-1.11.1-1.3-1.1-1.21.10.80.51.31.31.4-1.1-0.80.9-1.1-0.90.9-0.9-0.7-0.9-0.9-0.7-1.0
Delay disc. indifference point, 24s delay0.20.20.8-0.90.4-0.80.5-0.5-0.40.10.00.80.0-0.30.10.3-0.5-0.0-0.40.3-0.2-0.40.5-0.5-0.60.0-0.4-0.6-0.6
Delay disc. indifference point, 4s delay0.80.82.10.2-0.7-1.3-0.80.8-1.1-0.3-0.41.30.3-0.50.70.70.5-0.6-0.70.9-0.8-1.01.2-1.2-1.0-1.0-1.1-1.3-1.4
Delay disc. indifference point, 8s delay0.20.32.10.2-0.6-0.3-0.60.6-0.0-0.9-0.90.31.50.70.30.10.60.20.1-0.2-0.20.10.1-0.0-0.0-0.3-0.0-0.0-0.7
Indifference point function ln k2.03.49.72.1-2.8-2.9-2.82.8-1.6-2.9-2.82.53.12.62.11.40.80.20.30.4-0.00.1-0.1-0.40.00.7-0.2-0.3-1.8
Indifference point function log k2.03.49.72.1-2.8-2.9-2.82.8-1.6-2.9-2.82.53.12.62.11.40.80.20.30.4-0.00.1-0.1-0.40.00.7-0.2-0.3-1.8
Patch foraging total patch changes 0 sec0.10.21.2-0.50.40.10.4-0.40.10.90.8-0.1-1.1-0.7-0.2-0.3-0.8-0.0-0.20.40.2-0.30.3-0.5-0.30.4-0.4-0.5-0.1
Patch foraging total patch changes 12 sec1.82.48.1-1.72.02.11.9-1.91.32.82.6-1.8-2.5-2.8-1.5-1.2-1.0-0.4-0.70.3-0.4-0.80.8-0.5-0.7-0.9-0.5-0.80.5
Patch foraging total patch changes 18 sec0.40.72.7-0.81.21.01.2-1.20.61.41.4-0.9-1.6-1.0-0.9-0.7-0.60.00.0-0.20.2-0.0-0.10.20.20.20.20.20.8
Patch foraging total patch changes 24 sec1.62.710.4-1.71.7-0.01.8-1.8-0.52.72.30.2-3.2-3.1-0.7-0.0-1.0-1.0-1.71.3-0.8-1.81.7-1.5-1.7-0.9-1.4-1.8-0.3
Patch foraging total patch changes 6 sec0.40.71.6-0.70.6-0.10.5-0.5-0.31.00.90.2-1.3-1.3-0.10.1-0.1-0.7-1.10.9-0.7-1.01.2-1.0-1.2-0.5-1.0-1.2-0.7
Patch foraging time to switch 0 sec0.81.54.20.6-0.40.4-0.30.3-0.4-0.2-0.3-0.1-1.0-0.71.01.41.6-1.9-1.91.5-1.9-1.51.6-1.4-1.7-2.0-1.5-1.3-1.0
Patch foraging water rate 0 sec0.40.94.80.1-0.3-1.6-0.30.3-0.7-0.5-0.41.20.81.0-0.1-0.4-1.31.21.1-0.71.30.8-0.90.81.02.20.90.70.5
Patch foraging water rate 12 sec0.81.66.00.6-1.2-2.5-1.21.2-1.0-1.5-1.32.02.01.80.50.2-0.91.41.3-0.71.31.0-1.00.80.91.70.70.5-0.3
Patch foraging water rate 18 sec0.81.28.00.6-1.3-2.8-1.21.2-1.8-1.1-1.12.61.20.71.00.8-0.10.10.10.60.0-0.30.4-0.3-0.20.3-0.4-0.8-1.3
Patch foraging water rate 24 sec0.60.82.30.6-0.9-1.5-0.80.8-0.9-1.3-1.21.21.51.40.50.1-0.20.80.8-0.40.70.6-0.40.70.61.40.70.5-0.2
Patch foraging water rate 6 sec0.60.83.80.2-0.9-2.0-0.90.9-0.8-0.9-0.91.71.41.30.50.2-0.91.00.8-0.40.90.6-0.50.70.41.20.50.1-0.5
Seeking ratio, delayed vs. immediate footshock0.30.32.10.1-0.2-1.5-0.20.2-1.30.30.11.4-0.2-0.40.30.4-0.1-0.3-0.40.5-0.1-0.50.4-0.7-0.5-0.2-0.6-0.6-0.4
Distance traveled before self-admin0.70.93.40.20.4-0.00.3-0.3-0.81.11.00.1-1.8-1.8-0.00.40.5-1.2-1.21.1-0.9-1.21.1-1.0-1.1-1.0-1.2-1.00.1
Distance traveled after self-admin0.60.81.6-1.01.21.11.2-1.20.91.21.2-1.1-0.9-0.8-1.1-0.9-0.90.50.5-0.60.70.4-0.60.40.60.50.30.41.0
Extensor digitorum longus weight1.87.029.4-2.52.71.02.6-2.6-0.44.43.8-0.5-4.4-5.4-1.4-0.4-0.2-2.0-2.32.1-1.6-2.62.5-2.5-2.5-3.1-2.6-3.0-1.0
Bone: elastic displacement0.60.71.7-0.5-0.00.6-0.00.01.3-0.2-0.1-0.71.20.7-0.5-0.6-1.11.31.2-1.01.21.1-1.00.80.90.70.90.70.2
Bone: elastic work0.40.52.0-1.40.80.50.8-0.80.81.11.0-0.3-0.4-1.1-0.6-0.3-0.90.20.10.10.1-0.30.5-0.3-0.4-1.0-0.4-0.8-0.7
Bone: endosteal estimation3.37.312.83.2-3.0-2.7-3.03.0-3.1-2.6-2.92.70.31.33.43.43.6-2.9-2.72.7-2.8-2.62.6-2.5-2.4-1.9-2.5-1.9-2.4
Bone: endosteal perimeter3.47.114.43.7-3.2-2.7-3.23.2-3.3-2.8-3.02.60.71.63.33.23.8-2.9-2.62.4-2.8-2.32.2-2.2-2.2-1.5-2.2-1.4-1.9
Epididymis fat weight1.24.111.93.4-3.0-2.1-3.03.0-2.3-2.0-2.11.8-0.41.12.82.82.2-2.0-1.62.0-1.5-1.51.4-1.5-1.3-0.9-1.5-1.0-1.0
Delta time in closed arm before/after self-admin0.70.72.4-0.5-0.4-1.2-0.30.3-0.70.60.51.2-0.1-0.80.40.4-0.4-0.3-0.71.0-0.5-0.91.1-0.9-1.1-0.7-0.8-1.6-1.5
Delta time in open arm before/after self-admin0.60.64.6-0.41.10.51.1-1.1-0.11.21.0-0.5-2.2-1.4-0.6-0.3-0.4-0.5-0.50.3-0.1-0.50.3-0.4-0.30.1-0.5-0.10.9
Diff in mean of infusions in LGA sessions0.70.93.4-0.80.71.40.8-0.81.21.81.8-1.2-1.3-1.7-1.1-1.1-1.20.20.0-0.00.1-0.20.1-0.1-0.1-0.1-0.3-0.50.4
Delay discount exponential model param0.50.51.1-0.10.41.00.4-0.41.00.40.5-1.1-0.20.2-0.7-0.7-0.70.70.7-0.70.90.8-1.00.90.80.70.90.91.0
Extinction: sum of active levers before priming0.91.04.4-0.50.60.60.7-0.7-0.11.61.4-0.4-2.1-2.1-0.40.00.1-0.9-0.90.9-0.7-1.10.9-1.0-0.9-1.3-1.0-1.1-0.2
Active lever presses in extinction session 61.11.14.5-0.71.22.11.3-1.31.21.71.5-1.9-1.7-1.7-0.9-0.6-0.3-0.5-0.40.3-0.3-0.50.2-0.3-0.2-0.5-0.6-0.20.7
Bone: final force1.01.64.0-0.30.50.00.5-0.5-0.61.00.80.2-1.9-1.70.30.90.8-1.6-1.61.5-1.5-1.81.8-1.4-1.6-2.0-1.5-1.6-0.8
Bone: final moment1.01.64.6-0.30.40.20.4-0.4-0.41.10.90.0-1.9-1.80.30.90.7-1.6-1.61.5-1.5-1.81.9-1.4-1.6-2.1-1.5-1.6-0.8
Food consumed during 24 hour testing period0.20.32.2-0.81.00.31.0-1.00.10.30.4-0.4-1.5-0.1-0.3-0.0-0.40.10.1-0.10.50.1-0.20.20.30.80.30.30.6
Glucose2.64.18.62.6-2.9-2.0-2.92.9-1.6-2.9-2.91.91.71.92.62.42.4-1.5-1.41.4-1.8-1.21.3-1.1-1.3-1.3-1.2-1.0-1.9
Heart weight2.64.17.32.1-2.7-2.1-2.72.7-2.2-1.9-2.02.21.10.62.32.22.4-1.7-1.61.9-1.8-1.61.8-1.8-1.8-2.0-1.8-1.9-2.5
Delay discount hyperbolic model param0.50.61.1-0.40.60.90.6-0.61.00.50.6-1.0-0.30.1-0.8-0.8-0.80.80.8-0.80.90.9-1.00.90.90.80.90.91.1
Intermittent access intake day 1-15 change0.30.52.00.6-0.10.4-0.10.10.5-0.7-0.6-0.50.21.10.1-0.1-0.20.40.6-0.70.60.8-0.91.10.91.11.01.41.3
Intermittent access intake escalation0.40.82.70.6-0.00.8-0.00.00.8-0.8-0.7-0.80.41.3-0.0-0.2-0.10.50.8-0.90.60.9-1.11.31.11.11.11.71.5
Intermittent access intake escalation 20.20.31.40.6-0.10.7-0.00.00.7-0.3-0.2-0.7-0.40.50.10.1-0.30.00.1-0.30.20.3-0.40.70.40.80.50.91.2
Intermitt. access day 1 inactive lever presses0.20.72.2-0.00.30.70.3-0.30.7-0.7-0.4-0.81.01.3-0.3-0.4-0.00.70.9-1.10.81.1-1.21.01.10.91.21.51.1
Intermitt. access day 15 inactive lever presses1.12.46.82.2-1.5-2.3-1.51.5-2.6-0.1-0.32.1-1.5-0.91.41.71.1-1.8-1.81.9-1.2-1.51.4-1.5-1.5-0.9-1.4-1.2-0.1
Intermitt. access escalation Index0.40.62.40.6-0.9-1.5-0.90.9-1.0-0.8-0.71.31.40.90.40.20.00.60.5-0.30.50.6-0.50.50.40.50.50.3-0.2
Intermittent access day 1 total infusions6.310.220.34.0-3.9-4.4-3.93.9-4.5-2.7-3.14.30.60.73.84.03.5-3.1-2.73.1-2.8-2.52.5-2.8-2.5-2.5-2.5-2.3-2.6
Intermittent access day 15 total infusions2.94.413.43.7-3.2-2.4-3.13.1-2.4-2.8-3.02.21.11.92.82.72.4-1.7-1.11.3-1.4-0.70.7-0.8-0.7-0.7-0.6-0.1-0.6
Intermittent access terminal intake (last 3 days)5.06.516.84.1-3.5-3.0-3.53.5-3.2-2.4-2.82.80.30.93.23.42.9-2.7-2.22.4-2.3-1.81.8-1.8-1.8-1.7-1.7-1.2-1.2
Intermittent access total infusions6.27.315.94.0-3.7-3.3-3.63.6-3.4-2.6-3.03.20.71.03.43.53.1-2.7-2.22.5-2.3-1.91.9-2.0-1.9-1.9-1.8-1.5-1.7
Intermittent access day 1 locomotion4.76.012.23.0-3.0-3.5-2.92.9-3.5-1.7-2.13.40.00.32.93.02.4-2.4-2.22.5-2.1-2.11.9-2.3-2.0-1.8-2.0-1.9-2.1
Intermittent access day 15 total locomotion2.34.111.23.3-2.8-2.7-2.82.8-2.8-1.6-1.82.5-0.60.52.52.62.0-2.2-1.82.0-1.5-1.51.4-1.5-1.4-1.0-1.5-1.0-0.8
Intermittent access total locomotion8.410.120.64.5-3.9-4.3-3.93.9-4.5-2.3-2.74.1-0.70.53.94.13.2-3.4-3.13.3-2.7-2.72.5-2.8-2.6-2.0-2.5-2.0-1.8
Intermittent access standard deviation0.20.31.71.3-1.0-0.3-1.01.0-0.2-0.8-0.70.20.21.00.80.60.4-0.3-0.30.2-0.10.0-0.00.3-0.00.30.10.40.3
Left kidney weight0.73.28.12.1-2.1-2.6-2.12.1-2.9-1.6-1.82.4-0.20.52.12.22.2-1.7-1.51.6-1.6-1.31.2-1.5-1.4-1.2-1.4-1.1-1.3
Right kidney weight0.31.43.11.5-1.3-1.6-1.41.4-1.8-1.0-1.11.5-0.50.21.41.61.4-1.2-1.11.1-1.0-0.90.8-1.1-0.9-0.8-1.1-0.8-0.7
Cocaine induced anxiety0.10.10.50.10.20.30.2-0.2-0.10.20.2-0.3-0.5-0.1-0.4-0.30.10.10.3-0.30.10.3-0.30.50.40.30.30.50.7
Post-drug Anxiety0.10.10.4-0.10.30.20.3-0.3-0.20.50.6-0.1-0.5-0.6-0.4-0.30.2-0.1-0.0-0.1-0.20.00.00.10.0-0.2-0.00.10.4
Baseline Anxiety0.10.20.4-0.70.3-0.40.3-0.3-0.10.60.60.40.2-0.6-0.2-0.2-0.30.1-0.20.2-0.1-0.20.3-0.4-0.4-0.4-0.3-0.7-0.6
Tail length0.51.95.1-2.32.00.91.9-1.91.11.81.9-0.8-0.7-1.2-1.8-1.7-1.91.31.2-1.11.40.8-1.00.60.90.90.60.40.7
Length with tail0.41.97.7-2.22.00.41.9-1.9-0.02.82.7-0.2-1.9-2.7-1.7-1.3-1.10.10.1-0.10.2-0.30.3-0.6-0.2-0.5-0.5-0.80.1
Length without tail0.72.412.1-1.71.4-0.21.4-1.4-0.72.92.70.4-2.5-3.5-1.1-0.6-0.7-0.6-0.80.9-0.5-1.31.4-1.5-1.1-1.4-1.2-1.9-0.6
Times rat made contact with spout0.50.61.6-1.31.1-0.51.1-1.1-0.20.70.80.4-0.0-0.4-0.9-1.0-0.90.80.7-0.60.90.5-0.40.40.50.90.50.30.3
Lifetime Intake4.75.712.43.5-3.4-2.9-3.43.4-2.9-2.2-2.52.80.90.93.03.02.7-2.3-1.92.2-2.0-1.61.7-1.9-1.7-1.7-1.6-1.4-1.8
Liver weight, left0.40.72.01.1-1.4-1.2-1.41.4-0.8-1.1-1.01.21.41.20.70.60.80.10.4-0.1-0.10.1-0.10.30.3-0.20.10.1-0.6
Liver weight, right1.32.35.01.5-2.2-1.6-2.22.2-0.9-2.2-2.11.62.21.51.81.71.3-0.6-0.50.8-1.0-0.70.8-1.0-0.7-1.0-0.9-0.9-1.9
Locomotor activity0.40.72.1-0.1-0.40.3-0.40.41.1-0.5-0.3-0.41.41.1-0.1-0.7-0.91.31.3-0.91.11.2-1.10.81.01.00.80.7-0.1
Locomotor testing distance0.30.52.60.0-0.80.3-0.80.81.1-0.8-0.6-0.41.61.20.4-0.1-0.70.90.9-0.40.80.8-0.60.30.60.70.40.2-0.7
Locomotor testing rearing0.30.63.00.4-1.10.6-1.11.11.3-0.9-0.7-0.71.71.20.40.0-0.30.70.5-0.40.50.7-0.30.30.30.30.40.2-0.6
Locomotion in novel chamber1.31.64.92.2-2.0-1.8-2.02.0-1.4-1.7-1.71.50.81.51.81.71.0-0.8-0.40.8-0.6-0.20.2-0.2-0.2-0.1-0.4-0.0-0.4
Locomotion in novel chamber post-restriction0.61.03.41.8-1.6-0.3-1.51.5-0.1-1.6-1.30.10.81.80.90.50.50.10.5-0.30.30.7-0.70.70.70.90.71.00.5
Fecal boli incidents, locomotor time 10.10.20.80.50.40.80.2-0.20.3-0.10.1-0.8-0.30.3-0.0-0.00.5-0.2-0.3-0.2-0.10.2-0.30.30.10.10.30.70.9
Change in fecal boli incidents, locomotor task0.70.74.80.2-0.9-0.9-0.90.9-0.4-1.6-1.50.92.21.20.60.60.70.20.4-0.2-0.10.2-0.1-0.10.2-0.3-0.1-0.1-1.0
Time >=10cm from walls, locomotor time 11.31.46.22.5-1.6-0.1-1.71.7-0.8-1.6-1.60.10.61.21.51.52.2-1.2-0.70.6-1.1-0.40.3-0.3-0.2-0.8-0.20.3-0.1
Bouts of movement, locomotor time 15.56.210.1-2.83.03.23.1-3.13.12.12.4-3.1-1.2-0.5-2.9-3.0-2.82.32.0-2.42.32.0-2.02.12.02.32.12.12.7
Total resting periods, locomotor time 14.24.78.0-2.42.72.82.8-2.82.72.02.2-2.8-1.4-0.5-2.4-2.5-2.41.81.6-2.01.91.7-1.71.81.72.01.71.82.4
Rest time, locomotor task time 10.50.72.10.3-0.1-0.2-0.20.20.1-1.0-0.8-0.00.81.4-0.0-0.2-0.40.80.9-0.90.91.1-1.01.11.01.30.91.30.9
Distance moved, locomotor task time 10.30.51.60.7-0.80.2-0.80.8-0.20.30.20.1-0.0-0.60.50.51.0-0.9-0.70.8-0.9-0.80.8-0.9-0.7-1.3-0.7-0.9-0.8
Vertical activity count, locomotor time 10.20.62.41.4-1.6-0.3-1.51.5-0.2-0.9-0.80.41.20.70.80.50.9-0.20.00.2-0.30.1-0.1-0.10.0-0.4-0.0-0.0-0.5
Time >=10cm from walls, locomotor time 20.40.62.40.00.61.50.6-0.61.10.40.5-1.6-0.50.1-0.6-0.6-0.30.30.6-0.70.60.7-0.80.70.90.80.81.11.3
Bouts of movement, locomotor time 20.40.72.6-1.01.10.81.1-1.10.61.61.6-0.7-1.4-1.3-1.0-0.7-1.00.3-0.1-0.10.3-0.20.10.0-0.10.1-0.0-0.20.6
Total resting periods, locomotor time 20.20.41.4-0.60.70.70.7-0.70.61.21.2-0.7-1.2-0.9-0.7-0.5-0.70.2-0.1-0.10.2-0.10.10.1-0.10.10.0-0.00.5
Rest time, locomotor task time 20.91.24.21.6-1.6-0.7-1.61.6-0.4-2.0-1.80.61.92.01.00.60.80.20.2-0.3-0.00.5-0.30.60.30.30.40.7-0.2
Distance moved, locomotor task time 21.11.44.0-1.41.32.01.4-1.41.71.51.6-1.8-0.7-0.9-1.4-1.5-1.00.70.8-0.80.90.6-0.70.50.80.50.80.50.8
Vertical activity count, locomotor time 20.70.92.1-1.00.51.00.6-0.61.40.60.7-1.00.60.0-1.0-1.2-1.31.21.3-1.11.31.1-1.00.91.10.90.80.70.5
Light reinforcement 10.20.51.2-0.40.70.40.7-0.70.60.60.7-0.6-0.3-0.0-0.7-0.9-1.10.80.6-0.70.90.9-0.60.80.71.00.70.70.9
Light reinforcement 20.30.52.31.5-0.6-0.0-0.70.7-0.4-0.5-0.6-0.1-1.20.11.01.20.6-1.0-0.90.9-0.6-0.50.4-0.3-0.4-0.6-0.5-0.00.6
Bone: marrow area3.47.413.13.2-3.1-2.8-3.13.1-3.1-2.7-3.02.70.51.53.43.43.6-2.9-2.62.6-2.8-2.52.5-2.4-2.4-1.9-2.5-1.9-2.4
Bone: maximum diameter0.61.12.60.9-0.4-0.6-0.40.4-1.30.0-0.10.7-1.3-0.60.91.11.2-1.6-1.61.4-1.3-1.41.4-1.1-1.3-0.7-1.2-0.9-0.4
Bone: maximum force2.44.38.90.5-0.1-0.7-0.10.1-1.81.00.71.0-2.6-2.31.01.91.8-2.8-2.92.6-2.6-2.93.0-2.5-2.6-3.0-2.6-2.5-1.4
Bone: maximum moment2.34.19.40.5-0.1-0.5-0.10.1-1.51.10.70.8-2.5-2.31.01.81.7-2.7-2.82.6-2.6-2.93.0-2.5-2.6-3.1-2.6-2.5-1.4
Mean time between licks in bursts0.10.31.7-1.30.5-0.40.5-0.50.20.50.40.50.5-0.6-0.4-0.2-0.80.50.3-0.10.3-0.10.2-0.5-0.2-0.6-0.5-0.8-0.9
Mean num. licks in bursts0.20.20.6-0.40.1-0.30.1-0.10.1-0.00.10.20.60.3-0.4-0.7-0.50.80.6-0.70.70.6-0.60.60.50.80.60.50.3
Cd content in liver0.30.41.61.1-0.60.5-0.50.50.2-1.0-0.9-0.60.41.20.50.30.6-0.10.1-0.20.00.5-0.70.40.40.60.50.90.6
Co content in liver1.61.84.5-1.20.50.60.5-0.51.4-0.3-0.0-0.81.31.1-1.0-1.5-1.72.01.8-1.81.91.7-1.51.61.52.11.61.30.6
Cu content in liver0.20.20.5-0.20.10.10.2-0.20.10.20.3-0.20.20.1-0.5-0.7-0.30.60.6-0.50.60.6-0.50.50.60.70.70.60.5
Fe content in liver0.10.10.40.4-0.40.7-0.30.30.2-0.3-0.3-0.60.60.30.20.00.6-0.2-0.20.1-0.5-0.10.2-0.2-0.2-0.20.00.1-0.1
K content in liver0.80.82.10.0-0.4-1.0-0.30.3-1.30.20.01.1-0.1-0.80.40.30.6-0.9-1.20.9-1.1-1.21.4-1.1-1.4-0.4-1.1-1.2-1.1
Mg content in liver1.01.02.00.5-1.0-1.4-1.01.0-1.3-0.5-0.71.40.4-0.11.00.80.6-0.8-1.01.1-0.9-1.11.3-1.3-1.3-0.3-1.2-1.3-1.4
Mn content in liver1.11.24.5-0.81.31.51.3-1.30.61.91.8-1.2-1.6-2.1-0.8-0.3-0.3-0.7-0.90.7-0.7-0.90.8-0.7-0.8-0.9-0.6-0.70.4
Na content in liver0.30.30.8-0.40.50.60.5-0.50.30.50.5-0.5-0.9-0.70.00.2-0.1-0.5-0.80.5-0.5-0.70.8-0.6-0.8-0.3-0.6-0.7-0.3
Rb content in liver0.91.03.41.1-1.7-1.2-1.61.6-0.6-1.7-1.61.11.81.70.90.40.60.40.5-0.30.20.5-0.30.10.30.40.40.3-0.7
Se content in liver0.20.22.10.6-0.1-0.3-0.00.0-0.80.10.00.3-1.5-0.30.30.40.3-0.7-0.50.6-0.2-0.40.2-0.4-0.20.3-0.3-0.10.5
Sr content in liver1.51.34.5-1.51.70.81.7-1.70.42.12.0-0.7-2.1-2.0-1.2-0.9-1.1-0.0-0.40.00.3-0.40.3-0.1-0.3-0.0-0.1-0.30.7
Zn content in liver0.91.03.0-0.90.6-1.50.7-0.7-1.61.31.11.5-1.7-1.6-0.2-0.1-0.5-0.6-0.90.8-0.2-1.01.0-1.0-1.00.2-1.0-1.2-0.4
Bone: minimum diameter3.05.69.62.7-2.5-2.0-2.52.5-2.4-2.0-2.22.00.10.82.93.12.8-2.7-2.72.6-2.7-2.52.5-2.3-2.4-2.0-2.4-1.9-2.0
Time in familiar zone, hab. session 10.50.41.10.4-0.5-0.5-0.50.5-0.6-0.1-0.20.5-0.6-0.30.70.80.3-0.6-0.90.8-0.6-0.81.0-0.8-1.0-0.6-0.9-0.9-0.8
Time in novel zone, hab. session 10.50.54.50.1-0.50.1-0.50.50.6-1.1-0.9-0.12.11.30.1-0.20.10.70.8-0.70.30.8-0.70.80.60.20.70.7-0.1
Total zone transitions, hab. session 10.00.10.3-0.20.30.20.3-0.30.10.50.6-0.1-0.2-0.5-0.4-0.3-0.10.0-0.1-0.10.00.1-0.10.2-0.1-0.20.10.00.1
Total locomotion distance, hab. session 11.01.42.41.4-1.4-1.5-1.51.5-1.6-1.0-1.11.50.10.31.41.41.3-1.2-1.21.1-1.0-1.11.0-0.9-1.1-0.8-1.0-0.9-1.0
Locomotion velocity, hab. session 10.50.72.00.8-0.7-1.3-0.80.8-1.4-0.3-0.41.3-0.5-0.30.70.80.7-0.9-0.90.8-0.6-0.90.8-0.7-0.9-0.6-0.8-0.8-0.7
Time in familiar zone, hab. session 20.40.41.1-0.90.30.20.3-0.30.80.00.1-0.20.90.3-0.7-0.9-0.81.10.9-1.00.70.9-0.70.60.50.50.60.4-0.1
Time in novel zone, hab. session 20.60.61.50.6-0.2-0.1-0.20.2-0.70.0-0.00.2-0.7-0.50.71.00.7-1.1-1.11.2-0.9-1.11.0-0.8-1.0-1.0-0.9-0.9-0.4
Total zone transitions, hab. session 21.11.43.50.3-0.5-1.2-0.50.5-1.30.40.11.3-0.0-1.30.50.80.9-1.2-1.41.4-1.5-1.41.6-1.5-1.6-1.9-1.4-1.7-1.4
Total locomotion distance, hab. session 21.62.13.81.1-1.4-1.9-1.41.4-1.9-0.7-1.02.00.3-0.31.41.41.3-1.4-1.61.5-1.5-1.51.6-1.5-1.7-1.5-1.5-1.7-1.7
Locomotion velocity, hab. session 21.72.23.81.3-1.5-1.9-1.51.5-1.9-0.9-1.11.90.2-0.11.51.61.5-1.5-1.61.5-1.5-1.51.6-1.5-1.7-1.5-1.5-1.6-1.6
Novel to familiar place preference ratio0.60.64.3-0.10.70.50.8-0.8-0.41.31.2-0.4-2.1-1.6-0.4-0.10.3-0.8-0.70.7-0.3-0.80.6-0.5-0.3-0.5-0.5-0.50.5
Novelty place preference0.40.43.20.10.50.40.6-0.6-0.31.00.9-0.4-1.8-1.3-0.3-0.10.2-0.6-0.60.6-0.2-0.60.5-0.3-0.2-0.3-0.3-0.30.5
Time in novel zone, NPP test0.40.42.80.10.40.20.4-0.4-0.41.00.8-0.2-1.7-1.3-0.20.00.3-0.7-0.70.7-0.3-0.70.6-0.5-0.4-0.5-0.5-0.50.3
Total zone transitions, NPP test0.20.41.3-0.20.40.70.3-0.30.30.80.7-0.5-0.6-1.0-0.2-0.20.4-0.5-0.70.5-0.8-0.50.5-0.6-0.8-1.2-0.4-0.7-0.5
Total locomotion distance, NPP test0.60.81.40.9-1.0-1.1-1.11.1-1.1-0.6-0.71.10.40.00.90.80.9-0.8-0.90.9-1.0-0.80.8-0.9-1.0-1.0-0.9-1.0-1.2
Locomotion velocity, NPP test0.20.30.60.6-0.6-0.8-0.70.7-0.8-0.5-0.50.80.40.10.50.50.7-0.4-0.50.5-0.6-0.40.4-0.5-0.6-0.6-0.5-0.5-0.8
Intraocular pressure1.31.85.2-0.41.01.51.0-1.01.30.50.8-1.6-0.50.3-1.1-1.4-1.21.21.3-1.11.51.5-1.71.41.62.31.51.72.1
Delta distance traveled before/after self-admin0.91.02.1-1.00.50.70.4-0.41.40.00.1-0.71.10.7-0.8-1.1-1.31.41.4-1.21.31.2-1.20.91.21.11.00.80.3
Delta ambulatory time before/after self-admin0.81.02.0-0.80.30.80.3-0.31.4-0.4-0.3-0.81.41.0-0.6-1.0-0.91.41.4-1.31.21.3-1.21.11.21.01.10.90.2
Parametrial fat weight2.25.211.23.3-3.1-2.9-3.13.1-2.9-3.0-3.12.60.61.83.02.72.6-1.9-1.81.6-2.0-1.21.5-1.6-1.5-0.9-1.5-0.9-1.4
Pavlov. Cond. lever latency0.60.82.10.2-0.30.1-0.20.20.3-0.8-0.6-0.21.41.3-0.3-0.8-0.01.00.9-1.10.81.3-1.21.50.91.11.31.30.7
Pavlov. Cond. magazine entry latency0.91.13.70.30.0-0.6-0.00.0-1.10.70.50.7-1.9-1.30.50.90.5-1.4-1.31.3-1.1-1.51.4-1.5-1.3-0.9-1.5-1.3-0.6
Pavlov. Cond. change in total contacts0.40.42.30.30.40.50.3-0.3-0.00.60.4-0.5-1.5-0.80.20.50.1-0.9-0.80.7-0.5-0.80.6-0.8-0.5-0.3-0.7-0.40.3
Pavlov. Cond. index score0.40.52.7-0.40.80.50.7-0.70.21.10.9-0.5-1.6-1.2-0.20.2-0.4-0.6-0.40.5-0.2-0.70.6-0.8-0.4-0.4-0.7-0.60.1
Pavlov. Cond. latency score0.40.52.0-0.20.50.00.4-0.4-0.20.80.6-0.0-1.4-1.10.10.5-0.2-0.7-0.60.8-0.5-0.90.8-1.0-0.5-0.7-0.9-0.9-0.3
Pavlov. Cond. lever contacts0.60.72.10.0-0.0-0.3-0.10.1-0.50.50.30.4-1.0-0.90.50.90.3-1.0-0.91.1-0.9-1.31.2-1.4-0.9-1.1-1.4-1.3-0.9
Pavlov. Cond. magazine entry number0.50.63.30.6-1.1-0.7-1.11.1-0.4-1.4-1.30.71.81.20.70.40.70.10.0-0.0-0.30.10.10.2-0.2-0.30.20.1-0.7
Pavlov. Cond. intertrial magazine entries0.60.72.3-0.40.7-0.00.7-0.70.00.50.6-0.2-0.7-0.1-0.8-0.7-1.10.80.9-0.81.21.0-1.10.91.11.31.11.11.5
Pavlov. Cond. lever-magazine prob. diff.0.40.62.8-0.40.80.80.7-0.70.31.10.9-0.7-1.7-1.2-0.10.3-0.3-0.7-0.60.6-0.4-0.80.7-0.9-0.5-0.5-0.8-0.70.1
Pavlov. Cond. response bias0.40.53.7-0.40.80.30.7-0.7-0.01.21.1-0.3-1.9-1.3-0.30.1-0.5-0.6-0.50.5-0.2-0.60.5-0.8-0.3-0.0-0.7-0.60.2
Pavlov. Cond. lever latency0.40.52.10.0-0.6-0.6-0.60.60.0-1.0-0.80.51.51.10.0-0.4-0.30.81.1-0.80.70.8-0.80.60.90.90.70.6-0.0
Pavlov. Cond. magazine entry latency1.51.87.8-1.41.61.01.6-1.60.22.62.4-0.7-2.5-2.8-1.2-0.8-0.5-0.6-1.00.5-0.5-0.70.8-0.6-1.0-1.1-0.7-0.90.4
Pavlov. Cond. change in total contacts0.71.26.3-0.01.01.71.0-1.00.71.71.5-1.5-2.5-1.7-0.40.10.2-1.0-1.10.8-0.8-0.80.7-0.6-0.7-1.3-0.6-0.50.6
Pavlov. Cond. index score1.01.46.8-0.51.11.01.1-1.10.12.01.8-0.8-2.6-2.2-0.6-0.10.1-1.0-1.30.9-0.8-1.01.0-0.8-1.1-1.3-0.9-0.80.4
Pavlov. Cond. latency score0.91.26.0-0.20.90.80.9-0.9-0.21.81.6-0.5-2.4-2.1-0.40.10.3-1.2-1.41.0-0.9-1.01.0-0.9-1.1-1.3-0.9-0.90.3
Pavlov. Cond. lever contacts0.30.52.4-0.20.70.90.7-0.70.31.00.9-0.8-1.5-1.0-0.30.10.1-0.6-0.90.5-0.4-0.50.5-0.4-0.6-0.7-0.4-0.40.3
Pavlov. Cond. magazine entry number2.32.811.31.5-2.1-1.5-2.12.1-0.4-3.2-3.01.23.23.41.50.80.60.81.2-0.70.60.9-0.90.81.01.40.81.0-0.7
Pavlov. Cond. intertrial magazine entries0.50.82.70.6-0.60.3-0.60.60.4-1.1-0.9-0.41.61.60.1-0.30.10.70.9-1.00.60.9-0.91.11.11.21.11.30.7
Pavlov. Cond. lever-magazine prob. diff.1.21.67.4-0.71.31.31.3-1.30.32.22.0-1.0-2.7-2.4-0.8-0.2-0.0-1.0-1.30.8-0.8-0.91.0-0.8-1.0-1.3-0.8-0.80.4
Pavlov. Cond. response bias0.91.24.8-0.61.21.01.2-1.20.21.81.6-0.8-2.2-2.0-0.5-0.0-0.0-0.9-1.20.8-0.8-0.91.0-0.8-1.1-1.2-0.8-0.90.1
Time in closed arm before self-admin0.20.20.80.9-0.30.1-0.40.4-0.3-0.6-0.6-0.1-0.10.10.50.70.9-0.6-0.50.4-0.7-0.30.2-0.4-0.2-0.3-0.40.00.2
Time in closed arm after self-admin0.30.31.30.4-0.7-0.4-0.70.70.1-1.1-1.00.41.11.10.80.80.4-0.1-0.10.2-0.4-0.00.1-0.1-0.1-0.2-0.2-0.2-0.7
Time in open arm before self-admin0.40.53.0-0.7-0.4-0.4-0.40.40.7-0.6-0.40.41.71.00.0-0.3-0.81.10.9-0.60.80.6-0.40.50.40.40.6-0.1-1.1
Time in open arm after self-admin0.30.41.1-1.10.8-0.00.8-0.80.01.00.90.1-0.7-0.8-0.8-0.8-0.90.50.4-0.40.70.1-0.20.30.20.40.1-0.10.2
Bone: periosteal estimation1.94.06.91.9-1.6-1.9-1.61.6-2.4-1.0-1.21.9-0.8-0.12.22.52.4-2.6-2.52.4-2.3-2.42.4-2.2-2.2-1.8-2.3-1.9-1.6
Bone: periosteal perimeter1.01.83.31.3-1.0-1.2-1.01.0-1.7-0.5-0.71.2-0.5-0.21.31.51.7-1.8-1.81.5-1.8-1.71.7-1.3-1.6-1.3-1.5-1.2-0.9
Bone: post-yield work4.46.412.42.8-2.0-1.2-2.02.0-2.2-1.5-1.81.4-0.90.22.83.13.5-3.4-3.42.9-3.5-3.03.1-2.6-2.9-2.8-2.7-2.1-1.9
Progressive ratio test 1 active lever presses0.91.12.41.5-1.4-1.4-1.31.3-1.5-1.2-1.41.40.70.81.21.31.4-0.9-0.70.7-0.8-0.50.5-0.5-0.5-0.7-0.5-0.2-0.6
Progressive ratio test 1 breakpoint0.81.02.21.4-1.4-1.3-1.31.3-1.5-1.2-1.41.30.70.81.21.21.5-0.9-0.70.6-0.8-0.40.4-0.5-0.5-0.7-0.4-0.2-0.5
Progressive ratio test 1 inactive lever presses0.30.51.20.3-0.1-0.5-0.10.1-0.70.40.40.6-1.1-0.80.40.60.3-0.8-0.90.9-0.6-0.80.9-1.1-0.9-0.7-0.9-0.8-0.3
Progressive ratio test 2 active lever presses1.92.25.92.4-2.0-1.8-1.91.9-1.8-1.8-1.91.70.31.02.02.21.6-1.5-1.31.3-1.2-0.80.9-0.9-0.9-0.7-0.7-0.3-0.4
Progressive ratio test 2 breakpoint1.92.25.72.4-2.0-1.8-1.91.9-1.9-1.7-1.91.70.20.92.02.21.6-1.5-1.31.3-1.2-0.90.9-0.9-1.0-0.7-0.7-0.4-0.4
Progressive ratio test 2 inactive lever presses1.72.89.23.0-2.5-2.6-2.52.5-2.4-1.5-1.62.3-0.00.72.12.11.3-1.4-1.21.4-0.9-0.80.8-1.1-0.9-0.2-0.8-0.4-0.1
Incentive Sensitization - Responses1.01.43.41.2-0.7-0.5-0.80.8-0.9-0.0-0.10.5-1.4-0.91.11.40.8-1.7-1.81.6-1.4-1.41.5-1.5-1.6-1.2-1.3-1.2-0.4
Incentive Sensitization - Breakpoint1.11.43.31.3-0.8-0.7-0.90.9-1.0-0.2-0.20.7-1.3-0.81.21.50.8-1.7-1.81.6-1.4-1.41.4-1.5-1.6-1.1-1.3-1.1-0.4
Sum of active levers in priming session hrs 5-63.12.86.7-1.32.22.62.2-2.22.01.81.9-2.5-1.8-1.1-1.9-1.7-1.50.80.9-1.21.11.0-1.21.21.21.31.01.52.5
Progressive ratio0.71.13.01.0-0.60.2-0.60.6-0.5-0.2-0.4-0.0-0.0-0.41.01.21.6-1.6-1.31.2-1.7-1.21.1-1.3-1.1-1.7-1.2-0.9-0.9
Food seeking constrained by brief footshock0.00.00.2-0.2-0.10.0-0.10.10.2-0.4-0.30.00.40.10.10.00.1-0.0-0.1-0.0-0.3-0.00.2-0.3-0.2-0.2-0.2-0.2-0.4
Seeking ratio, punishment vs. effort0.30.41.8-0.7-0.0-1.3-0.00.0-0.3-0.4-0.41.10.50.5-0.2-0.4-1.11.10.7-0.50.90.6-0.40.40.41.10.50.1-0.2
Retroperitoneal fat weight2.510.527.04.8-5.2-4.7-5.25.2-3.7-4.9-4.84.12.83.94.13.52.7-1.1-0.81.4-1.1-0.50.8-0.8-0.70.1-0.8-0.4-2.0
Reaction time number correct0.20.41.6-1.00.9-0.21.0-1.0-0.31.31.20.3-0.4-1.0-1.0-0.6-0.70.50.5-0.30.60.1-0.40.20.40.10.2-0.00.4
Reaction time mean minus median0.61.68.5-0.61.42.91.4-1.42.01.41.4-2.6-1.2-1.0-1.4-1.0-0.20.10.1-0.70.20.5-0.50.70.4-0.60.80.91.5
Reaction time mean minus median AUC0.71.75.9-1.01.42.41.4-1.41.91.31.4-2.2-0.5-0.6-1.6-1.4-0.70.80.6-1.20.80.9-0.91.30.80.31.31.21.5
Reaction time num false alarms0.40.52.4-0.7-0.1-0.2-0.10.10.7-0.4-0.20.11.60.9-0.3-0.5-0.91.21.1-0.81.00.8-0.60.60.80.90.60.3-0.5
Reaction time num false alarms AUC0.40.61.5-1.20.40.20.4-0.40.90.30.4-0.21.10.3-0.7-0.9-1.21.21.1-0.91.10.8-0.50.60.70.80.70.2-0.3
Reaction time trials correct on left0.20.41.6-1.00.9-0.21.0-1.0-0.31.31.20.3-0.4-1.0-1.0-0.6-0.70.50.5-0.30.60.1-0.40.20.40.10.2-0.00.4
Reaction time trials on left0.30.51.8-1.11.0-0.11.0-1.0-0.21.31.30.2-0.4-1.0-1.1-0.7-0.80.60.6-0.40.60.2-0.50.30.40.10.30.00.4
Reaction time mean0.20.31.10.30.20.90.1-0.10.60.20.3-0.90.00.1-0.5-0.50.10.20.2-0.60.30.6-0.60.80.40.00.80.91.1
Reaction time mean AUC0.20.31.00.40.10.90.0-0.00.50.20.2-0.80.10.1-0.4-0.40.20.10.1-0.50.20.5-0.60.80.40.10.80.91.0
Median of all reaction times0.10.10.50.7-0.3-0.3-0.40.4-0.5-0.1-0.10.30.10.10.10.00.4-0.1-0.1-0.0-0.10.1-0.20.40.0-0.00.40.40.5
Reaction time omissions0.81.13.6-1.01.31.91.2-1.21.61.11.2-1.8-0.1-0.6-1.3-1.4-0.60.70.7-1.00.50.8-0.91.00.70.11.00.91.0
Reaction time false alarm rate0.20.31.7-0.3-0.40.1-0.40.40.8-0.6-0.5-0.11.30.90.2-0.2-0.50.60.6-0.40.50.5-0.20.20.30.40.30.1-0.7
Reaction time premature initiation rate1.42.06.6-1.61.0-1.20.9-0.9-1.11.61.31.3-1.7-2.6-0.20.3-0.7-0.8-1.01.3-0.7-1.71.5-1.8-1.4-1.3-1.8-2.4-1.6
Reaction time premature initiations1.22.29.0-2.52.0-0.81.9-1.9-0.72.62.31.0-1.8-3.0-1.2-0.6-1.4-0.0-0.30.70.1-1.10.7-1.1-0.7-0.7-1.1-1.8-0.8
Std. dev. reaction times0.91.76.8-0.51.02.60.9-0.92.20.60.8-2.50.00.1-1.3-1.3-0.50.80.8-1.40.81.3-1.31.51.10.31.61.71.7
Reaction time trials completed0.30.51.8-1.11.0-0.11.0-1.0-0.21.31.30.2-0.4-1.0-1.1-0.7-0.80.60.6-0.40.60.2-0.50.30.40.10.30.00.4
Reaction time trials AUC0.20.31.3-0.90.8-0.30.8-0.8-0.31.21.10.4-0.3-0.9-0.8-0.5-0.60.50.4-0.20.50.1-0.30.20.30.10.2-0.10.2
Run reversals in cocaine runway, females2.32.35.60.4-0.9-1.7-0.90.9-1.6-0.4-0.61.9-0.1-0.51.41.71.0-1.4-1.61.8-1.7-1.82.0-1.7-1.9-1.8-1.9-2.2-2.4
Run reversals in cocaine runway, males0.30.31.00.0-0.10.3-0.10.10.4-0.5-0.4-0.31.00.7-0.2-0.40.00.60.7-0.70.50.7-0.60.70.70.40.70.70.3
Latency to leave start box in cocaine runway1.21.33.61.2-1.2-1.9-1.11.1-1.9-1.2-1.31.80.30.81.41.61.4-1.1-1.01.0-0.9-0.80.8-0.8-0.8-0.8-0.8-0.6-0.9
Latency to leave start box in cocaine runway, F0.30.31.20.4-0.4-1.1-0.30.3-1.0-0.1-0.21.0-0.5-0.10.50.60.4-0.5-0.60.6-0.3-0.50.5-0.5-0.6-0.3-0.6-0.5-0.4
Latency to leave start box in cocaine runway, M1.11.03.31.1-1.1-0.9-1.11.1-0.9-1.8-1.80.91.31.61.31.31.5-0.7-0.30.4-0.8-0.30.3-0.3-0.2-0.7-0.3-0.0-0.8
Std. dev. time between licks in bursts0.10.21.3-0.90.1-0.10.1-0.10.6-0.3-0.30.21.10.2-0.1-0.1-0.70.60.3-0.20.30.10.1-0.1-0.2-0.4-0.1-0.3-0.8
Total sessions with >9 infusions0.91.12.81.6-1.7-0.8-1.61.6-0.9-1.3-1.30.81.10.81.31.11.6-0.9-0.50.6-0.8-0.40.5-0.6-0.5-0.9-0.4-0.3-0.9
Short access day 1 total inactive lever presses1.51.97.01.9-2.0-2.6-2.02.0-2.3-0.9-1.02.40.00.41.61.50.9-1.0-0.71.3-0.5-0.80.8-1.1-0.7-0.4-0.9-1.0-1.1
Short access day 10 total inactive lever presses0.10.30.9-0.0-0.1-0.2-0.10.10.2-0.7-0.60.00.91.00.0-0.2-0.50.70.8-0.60.70.7-0.80.50.80.90.70.70.3
Short access day 1 total infusions2.02.66.32.4-2.5-2.5-2.52.5-2.3-1.9-2.02.31.31.21.91.71.8-1.0-0.61.0-0.8-0.40.6-0.8-0.5-0.7-0.6-0.5-1.2
Short access day 10 total infusions3.84.810.23.2-3.1-2.1-3.13.1-2.4-1.8-2.12.10.70.52.62.42.7-2.3-1.92.1-2.1-1.61.7-2.0-1.7-1.9-1.7-1.5-1.9
Short access total infusions3.14.09.12.8-3.0-2.0-3.03.0-2.2-1.9-2.12.11.30.82.42.12.5-1.7-1.41.6-1.6-1.21.4-1.6-1.4-1.8-1.3-1.3-2.0
Short access day 1 locomotion1.41.85.11.8-1.7-2.3-1.71.7-2.1-1.1-1.22.10.10.51.61.61.4-1.2-0.91.2-0.9-0.90.9-0.9-0.8-0.7-0.9-0.7-0.9
Short access day 10 total locomotion1.83.49.22.0-1.7-2.9-1.81.8-3.0-1.0-1.32.8-0.6-0.12.02.21.8-2.0-1.82.0-1.7-1.71.5-1.8-1.7-1.4-1.7-1.5-1.3
Short access total locomotion2.93.48.02.4-2.2-2.8-2.22.2-2.8-1.3-1.62.6-0.20.32.22.21.9-1.9-1.71.9-1.6-1.51.5-1.5-1.5-1.2-1.5-1.3-1.3
One hour access (0.3 mA shock)2.93.37.72.8-2.5-2.6-2.52.5-2.3-1.9-2.12.40.30.92.52.61.5-1.7-1.51.7-1.3-1.21.2-1.2-1.2-0.7-1.1-0.9-0.9
Compulsive drug intake2.02.49.3-3.12.61.12.6-2.61.41.71.8-1.1-0.6-1.0-1.9-1.7-2.11.51.0-1.11.20.8-0.80.60.60.80.70.20.5
One hour access (shock baseline)2.74.213.23.6-3.1-2.1-3.13.1-2.0-2.9-3.01.91.01.92.82.82.2-1.7-1.21.4-1.4-0.80.9-0.7-0.8-0.5-0.8-0.1-0.6
Social response proportion0.10.10.5-0.60.70.50.6-0.60.30.50.5-0.5-0.3-0.3-0.3-0.4-0.10.00.10.0-0.1-0.1-0.10.00.00.1-0.0-0.10.0
Social responses0.70.92.0-1.31.21.41.1-1.11.41.11.1-1.3-0.3-0.4-1.2-1.3-1.10.90.9-0.90.80.7-0.80.80.80.60.50.50.6
Social time0.50.71.8-0.80.71.10.7-0.71.20.70.8-1.10.7-0.0-1.0-1.3-0.70.90.9-1.00.70.9-0.70.90.80.50.80.70.5
Soleus weight0.82.49.42.0-2.3-0.5-2.32.30.4-2.9-2.70.32.73.11.51.20.50.60.9-0.40.50.8-0.80.90.90.60.80.9-0.3
Bone: stiffness0.50.92.40.20.3-0.30.3-0.3-1.20.70.60.4-1.6-1.20.20.51.2-1.4-1.31.0-1.3-1.31.3-0.9-1.0-1.1-1.0-0.8-0.2
Tibialis anterior weight2.58.434.6-3.64.12.14.1-4.10.55.45.0-1.6-5.1-5.9-2.8-1.8-1.4-1.0-1.30.9-0.6-1.51.4-1.6-1.3-1.7-1.4-1.90.5
Time to tail flick, vehicle, before self-admin1.41.43.01.0-0.9-0.8-0.80.8-1.2-0.4-0.60.9-0.3-0.41.21.41.5-1.6-1.41.4-1.7-1.41.3-1.4-1.3-1.6-1.4-1.2-1.0
Time to tail flick, vehicle, after self-admin1.01.43.70.6-0.9-0.2-0.80.8-0.6-0.2-0.40.40.1-0.51.01.11.6-1.4-1.41.3-1.7-1.41.5-1.2-1.5-1.9-1.3-1.5-1.6
Time to tail flick, test, before self-admin3.94.07.41.8-2.0-2.7-2.22.2-2.5-0.9-1.12.7-0.2-0.52.12.31.6-1.9-1.92.3-1.9-2.12.1-2.1-2.1-1.8-2.3-2.3-2.3
Time to tail flick, test, after self-admin0.20.21.2-0.10.41.10.4-0.40.70.50.6-1.1-0.9-0.2-0.4-0.50.1-0.00.0-0.20.20.2-0.20.10.20.20.10.40.6
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.30.10.30.0-0.00.20.30.3-0.20.1-0.3-0.1-0.20.3-0.1-0.20.2-0.2-0.20.3-0.1-0.3-0.5-0.2-0.4-0.6
Delta time to tail flick, test, before/after SA4.95.08.0-2.22.72.82.8-2.82.51.72.0-2.8-0.9-0.1-2.5-2.6-2.01.91.9-2.32.22.0-2.12.02.12.22.12.32.7
Tibia length0.51.49.0-0.51.50.81.5-1.5-0.21.91.8-0.7-3.0-2.1-0.60.0-0.2-1.1-1.10.8-0.6-1.10.9-0.7-0.6-0.5-0.6-0.51.0
Ambulatory time before self-admin0.50.73.80.30.50.40.4-0.4-0.41.21.0-0.4-1.9-1.7-0.20.20.4-1.1-1.00.9-0.7-1.00.8-0.7-0.8-0.7-1.1-0.70.4
Ambulatory time after self-admin0.10.10.70.20.20.00.1-0.1-0.20.30.2-0.1-0.8-0.5-0.10.1-0.1-0.2-0.20.20.1-0.10.0-0.1-0.00.2-0.4-0.00.4
Bone: tissue strength0.20.21.40.00.11.20.1-0.11.20.10.2-1.10.40.2-0.3-0.3-0.30.40.4-0.30.30.4-0.40.40.4-0.20.50.50.4
Total heroin consumption2.83.29.2-2.12.33.02.3-2.32.42.72.5-2.7-2.5-2.6-2.3-2.1-1.60.60.4-0.60.60.2-0.30.40.30.10.30.01.2
Bone: trabecular number0.91.63.50.7-0.30.1-0.30.3-0.90.50.30.1-1.5-1.30.81.11.3-1.9-1.91.9-1.6-1.81.4-1.7-1.6-1.5-1.6-1.4-0.7
Bone: trabecular spacing0.81.12.6-0.70.2-0.50.2-0.20.4-0.10.00.41.50.8-0.8-1.2-1.11.61.6-1.41.31.4-1.21.21.31.31.31.00.4
Bone: trabecular thickness0.30.41.21.1-1.00.1-1.01.0-0.2-0.7-0.7-0.10.00.40.80.90.9-0.6-0.40.5-0.6-0.40.2-0.3-0.2-0.7-0.4-0.2-0.2
Bone: trabecular tissue density2.53.69.20.8-0.71.5-0.70.72.1-1.9-1.4-1.62.63.0-0.3-0.9-0.52.02.3-2.11.72.6-2.42.42.51.82.62.81.5
Water consumed over 24 hours0.81.03.7-1.91.70.21.7-1.70.21.41.4-0.2-1.2-1.1-1.2-0.9-1.30.70.6-0.51.00.4-0.40.20.50.70.30.10.5
Number of responses in last shaping day0.10.20.7-0.70.30.30.4-0.40.50.70.8-0.3-0.5-0.4-0.2-0.3-0.90.20.20.10.4-0.10.1-0.10.00.2-0.2-0.4-0.3