Hub : Genes

Plaat3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Plaat3 0.06 0.04 1.6e-04 0.01 0.02 0.02 0.03 8.3e-03 1.1e-03 1.8e-03 4.5e-04
2 BLA alternative TSS XM_039101108.1 0.07 0.05 1.6e-03 0.03 0.02 0.01 0.03 8.3e-03 4.2e-02 7.1e-02 1.6e-02
3 Liver intron excision ratio chr1_204783209_204801036 0.06 0.04 2.3e-05 0.04 0.03 0.04 0.04 3.8e-05 1.4e-04 6.7e-05 1.7e-05
4 Liver intron excision ratio chr1_204801138_204808639 0.05 0.03 2.0e-04 0.03 0.03 0.03 0.03 2.1e-04 8.6e-04 2.2e-04 1.5e-04
5 pVTA mRNA stability Plaat3 0.22 0.11 1.5e-04 0.06 0.07 0.08 0.06 1.5e-03 6.0e-04 3.0e-04 1.8e-03
6 Adipose gene expression Plaat3 0.31 0.11 0.0e+00 0.18 0.17 0.18 0.18 1.2e-19 9.3e-19 8.0e-20 1.4e-19
7 IL mRNA stability Plaat3 0.36 0.13 1.2e-05 0.17 0.11 0.16 0.03 5.4e-05 1.6e-03 1.2e-04 6.6e-02
8 Brain mRNA stability Plaat3 0.13 0.08 2.1e-08 0.07 0.07 0.08 0.01 2.1e-07 3.3e-07 8.3e-08 3.9e-02
9 Brain isoform ratio XM_039101108.1 0.03 0.02 1.6e-03 0.01 0.01 0.01 0.01 4.1e-02 2.1e-02 1.9e-02 3.6e-02
10 RMTg gene expression Plaat3 0.31 0.12 5.3e-08 0.22 0.28 0.18 0.29 1.5e-06 2.7e-08 1.3e-05 2.4e-08
11 PL mRNA stability Plaat3 0.07 0.04 1.8e-07 0.03 0.05 0.05 0.05 3.3e-04 2.6e-06 5.8e-06 6.8e-06
12 Brain gene expression Plaat3 0.33 0.1 0.0e+00 0.32 0.35 0.35 0.35 2.1e-30 1.1e-33 9.4e-34 7.1e-34
13 Liver gene expression Plaat3 0.35 0.13 0.0e+00 0.22 0.26 0.25 0.25 1.5e-23 1.3e-28 1.1e-27 3.6e-27
14 Adipose alternative TSS NM_017060.2 0.03 0.02 7.0e-03 0 0 0 0 9.8e-02 2.0e-01 2.2e-01 1.2e-01
15 Adipose mRNA stability Plaat3 0.14 0.09 2.5e-09 0.07 0.07 0.05 0.06 4.1e-08 8.1e-08 1.6e-06 3.0e-07
16 pVTA gene expression Plaat3 0.41 0.13 0.0e+00 0.38 0.38 0.37 0.38 9.2e-18 1.9e-17 4.6e-17 2.3e-17
17 PL gene expression Plaat3 0.07 0.04 1.0e-06 0.06 0.05 0.06 0.06 1.3e-07 1.5e-06 1.1e-06 6.3e-07
18 NAcc gene expression Plaat3 0.28 0.09 0.0e+00 0.32 0.31 0.3 0.31 3.9e-37 3.7e-36 7.2e-35 2.1e-36
19 PL isoform ratio XM_039101108.1 0.04 0.03 2.1e-04 0.03 0.03 0.02 0.03 1.2e-04 2.7e-04 9.2e-04 3.8e-04
20 LHb gene expression Plaat3 0.5 0.15 1.3e-07 0.25 0.27 0.27 0.27 9.9e-07 3.9e-07 3.3e-07 3.7e-07
21 BLA gene expression Plaat3 0.1 0.06 5.0e-05 0.06 0.05 0.05 0.05 2.2e-04 8.3e-04 1.2e-03 1.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.81.32.60.21.0-0.70.7-0.10.8-0.50.3-1.1-1.61.3-1.61.4-1.41.21.41.41.2-1.21.31.4
Area under the delay curve0.50.60.9-0.50.5-0.90.90.20.1-0.90.5-0.8-0.60.8-0.80.8-0.90.80.90.90.8-0.80.90.9
BMI with tail3.711.921.80.81.8-1.51.5-1.83.2-1.2-0.0-2.9-4.43.4-4.74.2-4.54.34.54.14.3-4.34.24.2
BMI without tail0.91.93.80.40.4-0.50.5-1.21.5-0.0-0.5-0.7-1.51.2-1.91.7-1.71.91.71.71.9-1.81.71.7
Body weight1.87.618.12.7-0.70.9-0.9-4.04.31.4-2.7-0.5-2.90.9-3.42.7-3.33.03.23.13.1-3.13.03.1
Weight adjusted by age0.80.92.81.5-1.01.1-1.1-1.41.70.6-1.0-0.1-0.90.1-1.00.7-0.60.90.81.00.9-0.90.80.5
Bone surface1.42.56.71.60.40.4-0.4-1.42.20.4-0.6-0.9-2.61.5-2.31.8-1.81.71.91.71.6-1.61.81.7
Bone volume1.01.85.41.11.0-0.20.2-0.61.5-0.1-0.2-1.1-2.31.5-2.01.6-1.51.41.61.51.3-1.31.51.4
Breakpoint value in progressive ratio session1.11.24.92.2-1.21.7-1.7-1.61.51.6-1.31.1-0.1-0.90.1-0.4-0.2-0.4-0.1-0.6-0.40.3-0.40.1
Number of licking bursts0.00.00.10.1-0.30.3-0.3-0.30.20.20.20.0-0.40.1-0.20.1-0.20.00.20.1-0.0-0.00.20.3
Context. condit. distance diff. score0.80.92.0-1.41.1-1.41.41.0-0.8-1.41.0-1.2-0.40.9-0.50.9-0.30.90.50.80.9-0.90.80.3
Locomotion velocity, session 10.20.20.9-0.90.3-0.70.70.3-0.3-0.70.8-0.3-0.10.5-0.40.5-0.30.30.50.40.3-0.30.60.4
Locomotion distance, session 11.01.32.3-0.40.8-1.01.0-0.10.6-1.00.6-1.2-1.11.1-1.41.5-1.31.31.41.21.4-1.51.51.5
Locomotion velocity, session 21.01.13.41.4-0.50.5-0.5-1.51.90.4-1.1-0.3-1.00.3-1.31.0-1.11.21.21.21.1-1.01.11.1
Locomotion distance, session 20.20.20.6-0.10.1-0.40.4-0.10.3-0.50.2-0.2-0.20.4-0.60.4-0.70.60.80.50.6-0.60.60.8
Locomotion velocity, session 33.74.37.2-0.72.2-2.22.20.40.6-1.90.5-2.2-2.32.1-2.32.6-2.42.12.72.22.1-2.22.52.5
Locomotion distance, session 30.30.30.6-0.30.5-0.70.7-0.10.2-0.40.0-0.6-0.60.4-0.70.8-0.70.70.80.70.7-0.70.70.7
Stereotopy head waving bouts, day 33.23.75.5-1.42.0-2.32.31.2-0.4-2.31.0-2.4-1.72.2-1.92.0-2.22.12.02.02.0-2.02.11.9
Stereotopy head waving duration, day 31.01.22.2-1.11.4-1.51.51.0-0.5-1.40.6-1.4-0.91.3-0.91.2-1.11.01.01.00.9-0.91.20.9
Locomotion velocity, session 71.51.62.8-0.71.7-1.61.60.8-0.2-1.40.9-1.5-1.31.4-1.11.3-1.41.11.60.91.2-1.11.21.4
Locomotion distance, session 70.91.12.0-1.30.7-1.21.30.6-0.5-1.20.8-1.1-0.71.0-0.91.0-1.21.21.41.01.2-1.21.21.1
Stereotopy head waving bouts, day 70.20.21.20.51.1-0.50.50.20.4-0.3-0.2-0.7-0.70.7-0.60.7-0.10.30.00.40.3-0.30.50.0
Stereotopy head waving duration, day 70.60.73.01.60.10.6-0.6-1.31.70.8-1.50.0-0.90.2-0.80.7-0.30.50.20.60.4-0.40.70.3
Locomotion velocity, session 80.20.20.8-0.6-0.50.1-0.10.2-0.5-0.20.90.50.7-0.10.2-0.50.1-0.4-0.4-0.3-0.50.5-0.30.1
Locomotion distance, session 81.31.93.6-1.31.6-1.71.71.2-0.5-1.91.5-1.7-1.01.7-1.31.4-1.01.31.01.21.4-1.41.31.1
Degree of sensitization distance1.61.62.5-1.00.9-1.21.20.6-0.2-1.30.6-1.5-1.21.4-1.31.3-1.41.61.51.51.5-1.51.51.4
Degree of sensitization stereotypy0.30.32.01.40.30.4-0.4-0.71.20.6-0.8-0.0-0.60.2-0.50.40.10.1-0.10.20.1-0.00.2-0.1
Conditioned locomotion0.20.30.70.6-0.60.4-0.4-0.80.80.3-0.80.2-0.20.0-0.50.1-0.50.60.40.60.5-0.50.40.4
Cocaine response after cond. corrected0.80.93.8-2.01.1-1.51.51.1-1.3-1.41.4-0.80.10.7-0.20.4-0.80.10.60.30.2-0.40.40.7
Cocaine response after cond. not corrected0.60.62.6-1.61.0-1.41.40.9-1.0-1.21.0-0.60.10.6-0.20.3-0.50.10.50.30.2-0.40.30.4
Cocaine response before conditioning0.50.62.01.4-0.71.2-1.2-0.80.91.1-1.20.80.0-0.60.2-0.40.8-0.4-0.6-0.3-0.20.3-0.4-0.9
Saline control response1.01.35.01.5-1.91.7-1.7-2.21.91.5-1.50.9-0.4-0.7-0.50.2-0.40.50.40.60.6-0.50.50.2
Bone: connectivity density1.32.14.20.90.10.1-0.1-1.21.80.0-0.5-0.8-2.11.2-2.01.7-1.81.61.91.81.6-1.61.81.8
Bone: cortical apparent density0.91.12.20.9-1.51.4-1.4-0.90.51.2-0.91.31.0-1.31.0-0.91.2-0.7-1.0-0.9-0.80.8-0.9-1.4
Bone: cortical area0.50.82.11.3-0.10.5-0.5-1.01.50.4-0.9-0.4-1.40.4-1.10.9-0.91.01.00.90.9-0.90.90.7
Bone: cortical porosity0.20.30.70.1-0.10.2-0.20.1-0.30.50.20.50.6-0.40.6-0.80.2-0.8-0.3-0.8-0.70.7-0.9-0.1
Bone: cortical porosity0.40.50.90.4-0.60.7-0.7-0.4-0.00.9-0.10.90.8-0.70.7-0.90.4-0.9-0.4-0.9-0.80.8-0.9-0.2
Bone: cortical thickness1.72.77.32.4-2.62.4-2.4-2.72.22.4-2.41.90.5-1.90.4-0.60.3-0.3-0.3-0.4-0.40.5-0.4-0.5
Bone: cortical thickness0.30.41.60.4-1.30.7-0.7-0.90.40.7-0.50.80.7-0.90.5-0.50.1-0.2-0.0-0.4-0.10.2-0.3-0.1
Bone: cortical tissue density1.01.32.61.0-1.61.5-1.5-1.00.61.3-0.91.41.1-1.41.0-1.01.2-0.8-1.1-1.0-0.80.9-1.0-1.4
Condit. Reinf. active minus inactive responses0.30.31.81.1-0.40.6-0.6-0.81.10.6-1.40.3-0.2-0.3-0.30.3-0.10.30.20.40.3-0.30.30.1
Condit. Reinf. active-inactive response ratio0.60.71.80.8-0.80.9-1.0-0.50.50.9-1.31.10.6-1.00.6-0.60.9-0.7-0.9-0.5-0.70.7-0.5-1.0
Condit. Reinf. active responses0.50.61.71.20.30.1-0.1-0.51.30.2-1.3-0.5-0.90.3-0.90.9-0.60.90.80.90.9-0.90.80.8
Condit. Reinf. inactive responses1.01.22.20.21.3-1.01.00.40.4-0.80.1-1.5-1.21.2-1.11.1-1.21.31.31.21.3-1.31.01.4
Incentive salience index mean0.70.82.11.0-0.10.2-0.2-0.81.50.1-1.1-0.4-1.00.3-1.11.1-0.91.11.01.11.0-1.01.11.0
Condit. Reinf. lever presses0.81.11.90.70.3-0.10.1-0.61.4-0.2-0.6-0.9-1.30.7-1.31.4-1.21.31.21.31.3-1.31.41.3
Condit. Reinf. active minus inactive responses0.20.20.70.10.9-0.20.20.6-0.40.00.4-0.1-0.10.30.3-0.30.5-0.6-0.5-0.5-0.50.6-0.5-0.6
Condit. Reinf. active-inactive response ratio0.60.74.6-0.12.1-1.11.11.2-0.5-0.80.5-1.0-0.91.3-0.30.50.2-0.0-0.1-0.00.1-0.10.1-0.2
Condit. Reinf. active responses0.00.10.10.40.00.3-0.3-0.20.20.4-0.20.20.0-0.20.1-0.20.3-0.3-0.4-0.2-0.20.2-0.3-0.3
Condit. Reinf. inactive responses0.30.42.20.1-1.50.9-0.9-0.90.30.6-0.20.80.8-1.00.3-0.50.1-0.2-0.2-0.1-0.20.2-0.30.0
Condit. Reinf. lever presses0.40.62.21.4-0.41.0-0.9-1.21.50.9-0.80.0-1.00.1-0.80.5-0.40.50.40.50.6-0.50.40.2
Condit. Reinf. lever reinforcers received0.10.20.50.7-0.30.6-0.6-0.50.50.7-0.40.40.0-0.30.2-0.20.4-0.3-0.5-0.2-0.20.3-0.4-0.4
Conditioned reinforcement - actives0.70.72.3-0.80.6-0.40.41.4-1.4-0.51.5-0.40.50.50.7-0.70.6-0.9-0.9-0.8-0.90.9-0.9-0.6
Conditioned reinforcement - inactives0.60.72.4-0.81.5-1.31.31.4-0.8-1.20.7-1.4-0.60.8-0.10.5-0.00.20.20.40.2-0.20.3-0.4
Conditioned locomotion1.21.44.2-1.91.7-1.81.82.1-1.6-1.81.2-1.5-0.20.90.20.50.40.2-0.00.40.2-0.20.2-0.8
Patch foraging indifference point 0 sec0.20.41.60.50.10.1-0.1-0.80.90.5-1.3-0.0-0.6-0.1-0.50.7-0.10.60.60.60.8-0.70.6-0.3
Patch foraging indifference point AUC1.21.46.52.5-1.31.8-1.8-1.82.01.7-1.50.6-0.7-0.5-0.2-0.1-0.50.00.2-0.0-0.00.1-0.00.3
Delay disc. indifference point, 0s delay1.61.73.8-1.51.2-1.81.81.1-0.6-1.91.2-1.4-0.41.5-1.21.1-1.31.21.01.41.2-1.21.21.4
Delay disc. indifference point, 16s delay0.60.61.30.00.8-0.60.60.00.5-0.6-0.4-1.1-1.10.6-0.81.1-0.90.91.11.00.9-0.91.00.5
Delay disc. indifference point, 2s delay0.80.91.8-0.81.0-1.11.10.8-0.4-1.31.2-1.3-0.71.3-0.90.9-1.00.80.60.90.8-0.70.80.8
Delay disc. indifference point, 24s delay0.10.10.7-0.3-0.80.2-0.1-0.40.2-0.1-0.1-0.1-0.1-0.2-0.10.3-0.40.40.50.40.4-0.40.40.1
Delay disc. indifference point, 4s delay0.60.71.3-0.50.2-0.90.9-0.20.3-0.8-0.1-0.6-0.40.5-0.90.9-1.01.01.01.21.0-1.01.11.0
Delay disc. indifference point, 8s delay0.30.31.1-1.00.2-0.80.80.7-0.8-0.91.0-0.10.40.4-0.1-0.1-0.2-0.00.10.1-0.00.00.10.3
Indifference point function ln k2.13.014.0-3.72.0-2.82.82.6-2.7-2.61.9-1.20.80.80.20.50.40.2-0.00.40.4-0.30.4-0.6
Indifference point function log k2.13.014.0-3.72.0-2.82.82.6-2.7-2.61.9-1.20.80.80.20.50.40.2-0.00.40.4-0.30.4-0.6
Patch foraging total patch changes 0 sec0.20.31.70.4-0.30.3-0.3-0.90.80.8-1.30.3-0.3-0.5-0.20.40.10.40.40.40.6-0.40.4-0.5
Patch foraging total patch changes 12 sec2.22.89.63.1-1.72.0-2.0-3.13.02.2-2.50.9-1.3-0.8-0.80.4-1.30.71.10.50.8-0.60.70.8
Patch foraging total patch changes 18 sec0.40.51.71.3-0.71.1-1.1-1.11.01.3-0.90.6-0.2-0.50.1-0.20.1-0.10.0-0.3-0.00.1-0.3-0.2
Patch foraging total patch changes 24 sec3.03.610.72.7-1.61.7-1.7-3.23.31.7-2.90.1-1.8-0.5-1.51.4-1.81.51.91.61.5-1.51.61.0
Patch foraging total patch changes 6 sec0.60.81.70.7-0.40.3-0.3-1.31.30.5-0.8-0.2-1.10.3-1.10.9-1.11.11.21.11.2-1.11.10.4
Patch foraging time to switch 0 sec1.21.84.30.50.6-0.40.5-0.30.9-0.70.8-1.4-1.91.7-1.81.5-1.71.51.71.51.4-1.41.62.1
Patch foraging water rate 0 sec0.61.05.6-0.90.1-0.20.10.7-1.0-0.0-0.70.61.2-1.11.3-0.81.4-0.8-1.2-0.8-0.70.7-0.9-2.4
Patch foraging water rate 12 sec0.91.34.3-2.10.5-1.11.11.4-1.9-0.9-0.20.21.6-1.01.5-0.81.2-0.8-1.0-0.8-0.60.7-0.8-1.6
Patch foraging water rate 18 sec0.50.74.2-2.00.8-1.31.31.1-1.1-1.20.5-0.50.70.00.20.50.10.4-0.10.40.6-0.50.3-0.6
Patch foraging water rate 24 sec0.70.93.2-1.60.7-0.90.91.3-1.5-0.90.50.11.1-0.30.9-0.51.5-0.5-1.0-0.6-0.30.5-0.6-1.8
Patch foraging water rate 6 sec0.40.62.7-1.60.2-0.90.80.8-1.3-0.70.10.11.1-0.71.0-0.40.9-0.6-0.4-0.7-0.40.4-0.5-1.1
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.0-0.1-0.00.0-0.30.30.1-0.5-0.2-0.2-0.1-0.20.3-0.40.40.20.50.3-0.30.30.1
Distance traveled before self-admin0.80.83.51.9-0.10.7-0.7-1.41.81.0-1.70.1-1.0-0.2-0.60.5-0.70.60.60.40.4-0.60.50.5
Distance traveled after self-admin0.30.41.21.0-0.50.9-0.9-0.70.61.1-1.00.60.1-0.60.3-0.40.3-0.2-0.4-0.3-0.50.3-0.4-0.3
Extensor digitorum longus weight2.59.730.94.3-2.22.5-2.5-5.15.62.5-4.10.3-2.90.1-3.12.4-2.73.12.82.72.9-2.92.82.5
Bone: elastic displacement0.70.82.7-0.7-0.5-0.00.00.5-1.00.00.30.71.6-1.01.3-1.01.0-1.0-1.0-0.9-0.90.9-1.0-0.9
Bone: elastic work0.30.41.90.4-1.40.8-0.8-1.20.80.7-0.90.70.5-0.80.1-0.1-0.20.30.20.30.2-0.30.10.3
Bone: endosteal estimation3.37.212.4-2.23.4-3.13.12.2-1.1-3.22.3-3.5-2.73.5-2.62.5-2.32.52.42.52.4-2.52.42.5
Bone: endosteal perimeter3.26.614.6-1.93.8-3.23.22.6-1.2-3.02.3-3.5-2.73.6-2.42.2-2.12.22.02.12.1-2.12.02.1
Epididymis fat weight1.12.77.7-1.22.8-2.42.41.0-0.3-1.60.5-2.0-1.71.6-1.31.8-1.21.31.61.41.4-1.61.51.5
Delta time in closed arm before/after self-admin0.90.91.8-0.4-0.2-0.50.5-1.21.0-0.1-1.3-0.0-0.6-0.1-0.81.2-1.31.11.31.21.3-1.21.31.0
Delta time in open arm before/after self-admin0.60.63.71.9-0.61.2-1.2-1.01.30.9-1.20.2-0.6-0.5-0.10.10.40.3-0.10.10.1-0.10.1-0.5
Diff in mean of infusions in LGA sessions1.51.76.82.0-1.01.4-1.4-1.91.32.1-2.61.80.4-1.60.7-0.70.2-0.6-0.2-0.8-0.60.7-0.7-0.5
Delay discount exponential model param0.40.40.70.5-0.30.7-0.7-0.2-0.00.9-0.50.70.5-0.70.7-0.70.8-0.7-0.8-0.9-0.70.7-0.8-0.7
Extinction: sum of active levers before priming1.31.34.82.2-1.01.3-1.3-2.02.11.5-2.00.6-0.7-0.4-0.70.3-0.40.40.70.50.6-0.50.50.9
Active lever presses in extinction session 61.51.45.22.3-1.21.8-1.8-1.81.71.9-2.11.1-0.2-0.90.1-0.3-0.1-0.1-0.2-0.3-0.30.2-0.3-0.1
Bone: final force1.32.14.41.5-0.20.5-0.5-1.62.10.4-0.8-0.8-1.90.9-1.91.6-1.81.81.81.61.6-1.61.71.7
Bone: final moment1.32.04.41.5-0.20.5-0.5-1.62.10.4-0.9-0.7-1.90.8-1.81.5-1.71.71.71.61.6-1.61.61.7
Food consumed during 24 hour testing period0.10.20.70.2-0.60.8-0.8-0.20.00.40.20.0-0.1-0.20.2-0.20.6-0.3-0.4-0.2-0.30.3-0.3-0.7
Glucose1.92.96.4-2.32.5-2.42.42.5-1.9-2.52.5-2.1-0.92.1-0.80.9-0.90.80.80.60.7-0.80.70.8
Heart weight1.01.44.2-2.01.7-2.02.01.5-1.3-1.81.0-1.2-0.20.9-0.40.8-0.70.50.40.70.6-0.70.70.7
Delay discount hyperbolic model param0.50.50.90.5-0.40.8-0.8-0.2-0.10.9-0.50.80.6-0.80.8-0.80.9-0.8-0.9-0.9-0.80.8-0.9-0.8
Intermittent access intake day 1-15 change1.11.12.50.3-0.10.5-0.50.6-0.80.60.40.70.8-0.61.3-1.31.4-1.4-1.3-1.6-1.41.4-1.5-1.3
Intermittent access intake escalation0.70.71.90.40.10.3-0.40.3-0.50.60.10.70.6-0.51.1-1.01.1-1.1-1.0-1.4-1.11.1-1.2-1.1
Intermittent access intake escalation 20.60.61.21.1-0.40.9-0.9-0.40.21.1-0.70.70.2-0.70.8-0.70.9-0.8-0.6-1.0-0.80.8-0.9-0.9
Intermitt. access day 1 inactive lever presses0.70.72.5-1.41.3-1.21.21.6-1.4-1.11.1-0.80.10.80.2-0.00.3-0.3-0.3-0.1-0.30.3-0.1-0.4
Intermitt. access day 15 inactive lever presses1.21.33.00.11.7-1.31.30.30.5-1.0-0.7-1.6-1.51.0-0.91.5-1.01.11.21.31.1-1.11.30.6
Intermitt. access escalation Index0.70.61.7-1.21.1-1.31.30.6-0.4-1.10.6-0.9-0.20.4-0.20.8-0.80.60.70.50.6-0.50.60.6
Intermittent access day 1 total infusions5.96.815.2-2.33.8-3.93.92.3-0.8-3.52.5-3.4-2.03.1-2.02.6-2.02.01.82.42.0-2.02.11.9
Intermittent access day 15 total infusions2.62.910.8-1.83.3-2.92.92.5-1.5-2.32.3-2.0-0.72.0-0.30.8-0.30.30.20.40.3-0.30.30.3
Intermittent access terminal intake (last 3 days)2.93.211.9-0.93.5-2.92.91.6-0.4-2.11.4-2.4-1.62.3-1.31.7-1.21.21.11.31.1-1.11.21.1
Intermittent access total infusions3.23.611.5-1.43.4-3.13.01.9-0.7-2.41.8-2.5-1.52.3-1.21.7-1.21.21.01.41.2-1.21.21.1
Intermittent access day 1 locomotion6.16.312.0-2.13.2-3.53.51.5-0.2-3.11.9-3.1-2.12.9-2.32.8-2.22.42.22.62.4-2.42.42.0
Intermittent access day 15 total locomotion1.92.15.4-0.92.3-2.22.21.2-0.2-1.81.2-2.0-1.41.7-1.01.6-0.81.21.01.21.2-1.21.10.6
Intermittent access total locomotion6.27.115.4-1.43.9-3.63.61.60.1-3.01.6-3.5-2.83.2-2.43.1-2.12.52.32.62.5-2.52.51.8
Intermittent access standard deviation0.70.81.7-0.30.6-0.20.20.7-1.10.40.40.50.7-0.21.0-1.01.2-1.2-1.1-1.3-1.21.2-1.2-1.1
Left kidney weight0.20.51.30.21.1-0.90.80.10.4-0.4-0.9-0.7-0.80.6-0.70.8-0.80.70.60.80.8-0.80.8-0.2
Right kidney weight0.30.71.70.91.0-0.50.4-0.41.0-0.0-1.1-0.8-1.30.7-1.01.0-1.00.80.71.00.9-0.91.00.4
Cocaine induced anxiety0.10.10.50.70.4-0.00.1-0.20.6-0.2-0.4-0.3-0.60.3-0.40.4-0.10.40.40.20.3-0.30.30.1
Post-drug Anxiety0.30.32.01.4-0.30.7-0.7-0.70.90.6-1.20.4-0.3-0.2-0.2-0.20.0-0.10.2-0.0-0.10.10.00.2
Baseline Anxiety0.90.93.11.3-1.51.3-1.3-1.51.01.6-1.71.10.2-1.00.1-0.5-0.4-0.3-0.1-0.1-0.30.3-0.00.5
Tail length0.92.98.11.8-2.52.2-2.2-2.31.42.4-2.82.31.2-2.10.9-1.11.1-0.8-0.9-0.6-0.70.8-0.8-1.2
Length with tail0.93.311.82.8-2.32.2-2.2-3.43.02.4-3.41.3-0.4-1.3-0.80.3-0.90.80.80.90.7-0.70.80.7
Length without tail0.92.05.72.0-1.01.0-1.0-2.32.41.1-1.80.0-1.3-0.1-1.41.0-1.81.21.41.31.2-1.31.31.5
Times rat made contact with spout0.50.61.80.3-1.31.0-1.0-0.70.20.9-0.71.10.8-1.00.6-0.70.7-0.5-0.6-0.4-0.50.5-0.5-0.7
Lifetime Intake2.83.210.6-1.63.3-3.13.11.7-0.8-2.21.4-2.2-1.22.1-1.21.5-1.21.10.91.41.1-1.11.21.1
Liver weight, left0.20.31.1-0.91.1-0.90.90.6-0.7-0.41.0-0.20.20.4-0.0-0.00.5-0.0-0.3-0.30.0-0.0-0.3-0.2
Liver weight, right1.01.73.2-0.81.2-1.51.50.10.2-1.20.7-1.3-1.11.2-1.51.3-1.51.51.61.41.5-1.61.31.8
Locomotor activity0.50.82.3-1.5-0.0-0.40.40.6-1.30.10.10.71.5-0.91.2-0.91.1-0.9-0.9-0.7-0.80.8-0.9-0.9
Locomotor testing distance0.40.63.8-2.00.1-0.80.80.8-1.4-0.50.30.31.5-0.60.9-0.40.7-0.4-0.5-0.2-0.30.3-0.4-0.5
Locomotor testing rearing0.30.52.5-1.60.7-1.01.00.8-1.3-0.50.30.01.0-0.30.6-0.40.5-0.4-0.5-0.2-0.40.4-0.40.0
Locomotion in novel chamber1.11.34.5-1.22.1-1.61.61.7-1.1-1.51.8-1.8-0.61.5-0.20.7-0.10.40.10.20.3-0.30.20.0
Locomotion in novel chamber post-restriction1.01.23.7-1.41.5-1.31.31.9-1.8-1.01.4-0.40.60.40.8-0.61.2-1.0-0.9-0.8-0.80.8-0.9-0.9
Fecal boli incidents, locomotor time 10.10.10.70.60.40.2-0.20.4-0.10.10.9-0.4-0.60.5-0.1-0.10.1-0.4-0.2-0.3-0.30.2-0.3-0.0
Change in fecal boli incidents, locomotor task0.70.73.1-1.70.2-1.11.20.9-1.0-1.51.2-0.60.50.6-0.20.2-0.30.50.30.40.4-0.50.40.5
Time >=10cm from walls, locomotor time 11.61.75.8-0.92.4-1.81.81.8-1.0-1.62.1-1.7-0.92.0-0.70.7-0.60.30.30.30.3-0.30.30.7
Bouts of movement, locomotor time 14.54.98.61.8-2.72.9-2.9-1.40.32.7-1.92.81.6-2.51.9-2.32.5-2.1-1.9-2.1-2.12.3-2.0-2.2
Total resting periods, locomotor time 13.23.66.81.7-2.32.6-2.6-1.30.42.4-1.82.31.1-2.11.5-1.92.2-1.7-1.6-1.7-1.71.9-1.6-1.9
Rest time, locomotor task time 10.80.93.4-0.70.0-0.10.11.2-1.3-0.40.80.31.0-0.51.1-0.91.8-0.9-1.1-1.0-1.11.0-1.0-1.4
Distance moved, locomotor task time 10.40.52.50.10.6-0.60.5-0.40.6-0.00.0-0.4-0.70.7-0.80.7-1.60.60.50.60.8-0.80.61.1
Vertical activity count, locomotor time 10.50.52.0-1.01.4-1.31.31.0-0.8-0.80.8-0.50.10.60.00.1-0.80.0-0.1-0.0-0.00.0-0.10.3
Time >=10cm from walls, locomotor time 20.40.41.00.60.00.6-0.60.1-0.20.60.10.40.4-0.20.6-0.70.7-0.8-1.0-0.8-0.80.8-0.9-0.8
Bouts of movement, locomotor time 20.80.94.11.4-1.11.2-1.2-1.61.21.5-2.00.8-0.2-1.10.1-0.20.1-0.10.1-0.1-0.10.10.1-0.1
Total resting periods, locomotor time 20.50.52.71.0-0.70.8-0.9-1.10.91.1-1.60.6-0.2-0.80.0-0.10.2-0.10.1-0.1-0.10.10.0-0.1
Rest time, locomotor task time 21.21.44.2-1.91.6-1.71.72.0-2.0-1.61.9-0.70.50.80.5-0.30.6-0.5-0.4-0.5-0.70.6-0.5-0.3
Distance moved, locomotor task time 20.81.02.71.2-1.31.4-1.4-1.20.71.7-0.81.30.6-1.00.6-0.80.3-0.7-0.7-0.8-0.50.5-0.8-0.5
Vertical activity count, locomotor time 20.91.02.30.0-1.10.8-0.8-0.3-0.41.0-0.51.51.5-1.41.2-1.20.8-1.0-1.2-1.0-1.00.9-1.2-1.0
Light reinforcement 10.40.72.70.3-0.50.6-0.6-0.3-0.10.9-0.41.00.6-0.90.8-0.71.4-0.8-0.6-0.9-0.81.0-0.8-1.6
Light reinforcement 20.40.52.30.51.5-0.70.70.80.2-0.60.7-1.3-1.31.0-0.50.9-0.20.50.40.30.4-0.30.40.4
Bone: marrow area3.37.112.3-2.33.4-3.23.22.3-1.2-3.22.4-3.5-2.63.5-2.62.4-2.22.52.42.42.3-2.42.32.5
Bone: maximum diameter0.61.13.60.61.1-0.40.4-0.10.8-0.3-0.1-1.1-1.91.3-1.51.3-1.01.21.21.11.1-1.11.10.9
Bone: maximum force3.05.210.41.50.8-0.20.2-1.62.6-0.3-0.9-1.9-3.22.0-3.12.7-2.92.92.82.72.7-2.72.82.8
Bone: maximum moment2.84.89.41.50.8-0.20.2-1.62.6-0.2-1.0-1.8-3.11.8-3.02.6-2.72.82.72.62.6-2.62.62.7
Mean time between licks in bursts0.30.41.90.0-1.40.6-0.6-1.10.70.5-1.00.60.6-0.8-0.10.0-0.40.50.40.50.5-0.40.50.3
Mean num. licks in bursts0.30.41.1-0.2-0.40.2-0.20.1-0.40.2-0.50.61.0-0.70.7-0.70.8-0.5-0.8-0.5-0.50.5-0.6-1.0
Cd content in liver0.50.62.0-0.91.1-0.50.51.4-1.3-0.51.2-0.2-0.00.40.4-0.40.7-0.7-0.6-0.6-0.80.8-0.5-0.7
Co content in liver2.73.27.1-1.4-1.10.4-0.40.8-2.00.40.81.82.7-1.72.4-2.21.9-2.2-2.0-2.1-2.22.2-2.1-2.1
Cu content in liver0.20.20.70.3-0.60.6-0.6-0.60.30.9-0.40.70.3-0.60.3-0.20.1-0.5-0.0-0.2-0.50.4-0.2-0.1
Fe content in liver0.00.10.20.10.5-0.10.10.1-0.00.00.4-0.2-0.40.4-0.20.0-0.2-0.20.2-0.1-0.30.20.00.3
K content in liver1.81.73.20.80.4-0.40.4-0.61.3-0.3-0.5-0.9-1.51.2-1.81.5-1.81.71.71.71.7-1.81.61.5
Mg content in liver2.02.13.60.01.1-1.01.00.00.8-0.9-0.1-1.5-1.61.5-1.71.8-1.81.81.91.81.8-1.81.81.6
Mn content in liver0.91.03.81.9-0.51.2-1.2-1.51.91.3-1.10.1-1.1-0.1-0.70.7-0.90.40.60.50.4-0.40.61.0
Na content in liver0.40.41.11.0-0.30.4-0.4-0.71.00.4-0.4-0.3-0.90.3-0.70.6-0.70.70.70.50.8-0.80.60.7
Rb content in liver0.81.03.1-1.81.5-1.71.71.5-1.3-1.41.2-1.0-0.00.9-0.20.5-0.40.20.40.40.2-0.20.30.4
Se content in liver0.20.31.41.10.60.3-0.3-0.10.80.2-0.5-0.5-1.20.5-0.50.7-0.10.30.10.40.2-0.20.4-0.1
Sr content in liver2.32.16.72.5-1.82.0-2.0-2.62.42.0-2.41.1-0.4-1.2-0.10.0-0.20.20.10.10.2-0.20.2-0.2
Zn content in liver1.61.75.22.0-0.60.8-0.9-2.02.31.0-2.0-0.1-1.3-0.1-1.11.0-1.21.41.41.11.3-1.41.10.8
Bone: minimum diameter3.05.69.8-1.42.9-2.62.61.5-0.4-2.61.6-3.1-2.83.0-2.52.4-2.32.42.42.42.3-2.32.32.2
Time in familiar zone, hab. session 10.40.40.8-0.10.4-0.50.5-0.10.3-0.6-0.3-0.7-0.60.4-0.60.7-0.50.90.70.90.9-0.80.70.6
Time in novel zone, hab. session 10.60.61.9-1.20.1-0.50.51.0-1.3-0.41.40.30.9-0.00.7-0.70.3-0.8-0.4-0.8-0.80.7-0.6-0.3
Total zone transitions, hab. session 10.00.10.20.4-0.20.4-0.4-0.50.50.3-0.40.3-0.2-0.1-0.1-0.00.1-0.10.2-0.2-0.10.10.0-0.0
Total locomotion distance, hab. session 10.81.12.1-0.61.4-1.41.40.9-0.3-1.50.7-1.4-1.01.3-0.91.0-0.61.10.90.81.1-1.00.90.6
Locomotion velocity, hab. session 10.30.40.80.10.8-0.70.70.30.2-0.8-0.0-0.8-0.70.7-0.70.7-0.40.90.60.60.9-0.80.70.4
Time in familiar zone, hab. session 20.50.51.8-0.4-1.00.3-0.3-0.0-0.60.10.20.91.3-0.90.8-1.10.5-0.7-0.5-0.6-0.70.7-0.8-0.3
Time in novel zone, hab. session 20.70.71.80.20.7-0.30.3-0.20.8-0.2-0.3-0.9-1.40.8-1.01.3-0.91.00.90.90.9-0.91.10.7
Total zone transitions, hab. session 21.11.42.70.50.3-0.40.4-0.81.4-0.4-0.6-0.7-1.20.7-1.51.4-1.51.51.71.41.5-1.51.51.6
Total locomotion distance, hab. session 21.31.72.6-0.41.1-1.41.40.40.3-1.50.4-1.4-1.21.3-1.41.5-1.31.61.51.51.6-1.61.41.4
Locomotion velocity, hab. session 21.31.82.8-0.51.3-1.51.50.60.2-1.70.5-1.6-1.21.4-1.51.5-1.31.51.41.51.6-1.61.41.3
Novel to familiar place preference ratio0.80.83.11.7-0.10.8-0.8-1.31.80.9-1.5-0.0-1.40.1-0.80.8-0.60.60.40.50.6-0.50.70.6
Novelty place preference0.50.52.11.40.10.6-0.6-1.01.40.7-1.2-0.1-1.20.1-0.60.6-0.40.40.20.30.4-0.30.50.4
Time in novel zone, NPP test0.60.62.01.30.20.5-0.5-1.01.40.6-1.2-0.2-1.20.2-0.70.8-0.60.60.40.50.6-0.50.70.7
Total zone transitions, NPP test0.30.41.40.6-0.30.4-0.4-1.01.20.3-0.4-0.1-0.70.3-0.80.7-0.70.60.70.60.7-0.70.80.8
Total locomotion distance, NPP test0.50.71.1-0.60.8-1.01.00.30.1-1.00.4-0.9-0.60.9-0.90.9-1.01.00.90.91.0-1.00.91.0
Locomotion velocity, NPP test0.20.30.7-0.40.5-0.70.70.3-0.1-0.80.4-0.7-0.30.6-0.50.5-0.60.60.50.50.6-0.60.50.6
Intraocular pressure1.11.55.00.6-0.41.1-1.10.0-0.31.1-0.91.20.7-1.21.3-1.01.8-1.5-1.6-1.3-1.61.6-1.2-2.2
Delta distance traveled before/after self-admin0.40.41.0-0.9-0.3-0.10.10.6-1.00.00.70.51.0-0.30.7-0.80.6-0.6-0.7-0.5-0.60.7-0.6-0.5
Delta ambulatory time before/after self-admin0.60.61.7-1.2-0.3-0.20.30.9-1.3-0.31.20.41.2-0.20.8-0.90.7-0.8-0.9-0.8-0.80.8-0.8-0.5
Parametrial fat weight2.14.19.4-2.03.1-3.03.02.4-1.5-3.02.5-2.4-1.62.5-1.31.3-1.21.22.01.01.2-1.11.20.5
Pavlov. Cond. lever latency1.21.52.8-1.00.1-0.10.10.9-1.6-0.10.71.21.3-0.61.4-1.41.6-1.6-1.4-1.7-1.71.6-1.4-1.4
Pavlov. Cond. magazine entry latency1.21.53.01.20.2-0.00.0-0.81.5-0.2-0.9-1.1-1.50.7-1.41.2-1.71.51.51.51.5-1.51.31.7
Pavlov. Cond. change in total contacts0.40.41.20.90.30.2-0.2-0.20.80.0-0.4-0.8-1.10.6-0.80.6-0.60.70.50.80.7-0.60.60.5
Pavlov. Cond. index score0.40.51.31.2-0.40.6-0.6-0.81.20.4-0.8-0.5-0.60.0-0.60.5-0.70.70.50.80.7-0.70.50.6
Pavlov. Cond. latency score0.40.51.20.8-0.20.3-0.3-0.61.10.1-0.6-0.7-0.70.2-0.80.7-0.90.90.71.01.0-0.90.70.9
Pavlov. Cond. lever contacts0.50.61.40.4-0.0-0.10.1-0.40.8-0.2-0.3-0.9-0.70.5-0.90.9-1.01.10.91.21.1-1.10.90.8
Pavlov. Cond. magazine entry number0.40.52.4-1.50.7-1.11.10.9-1.1-1.01.2-0.20.30.40.00.20.1-0.00.1-0.1-0.00.00.1-0.1
Pavlov. Cond. intertrial magazine entries0.80.92.60.8-0.30.7-0.7-0.10.00.8-0.80.80.7-1.01.0-0.91.5-1.1-1.2-0.9-1.11.0-1.1-1.6
Pavlov. Cond. lever-magazine prob. diff.0.50.61.71.3-0.50.7-0.7-0.91.30.5-0.8-0.5-0.70.1-0.70.5-0.80.80.60.90.8-0.80.50.7
Pavlov. Cond. response bias0.40.51.71.3-0.40.7-0.7-0.91.20.6-1.1-0.3-0.7-0.1-0.50.4-0.60.70.50.70.7-0.60.40.6
Pavlov. Cond. lever latency0.40.61.8-0.7-0.2-0.30.20.8-1.1-0.30.50.61.3-0.51.0-1.00.7-0.9-0.9-0.8-0.90.8-0.9-0.6
Pavlov. Cond. magazine entry latency1.51.76.12.5-1.21.6-1.6-2.32.41.8-2.21.0-0.7-0.7-0.60.2-0.60.40.50.30.3-0.30.40.6
Pavlov. Cond. change in total contacts0.70.93.92.0-0.11.1-1.1-1.51.81.3-1.2-0.1-1.50.1-0.80.6-0.50.30.40.40.4-0.40.40.5
Pavlov. Cond. index score1.01.34.82.2-0.41.2-1.2-1.82.21.4-1.70.2-1.4-0.0-1.00.7-0.70.70.80.60.7-0.70.70.6
Pavlov. Cond. latency score1.01.24.32.0-0.20.9-0.9-1.72.11.2-1.5-0.0-1.50.2-1.20.9-0.80.90.90.80.8-0.80.80.7
Pavlov. Cond. lever contacts0.20.31.11.0-0.40.9-0.9-0.90.90.9-0.70.3-0.5-0.3-0.20.10.1-0.0-0.0-0.10.00.0-0.0-0.2
Pavlov. Cond. magazine entry number2.53.010.7-3.31.3-2.02.03.0-3.2-2.32.9-0.81.30.61.1-0.60.9-0.9-0.9-0.7-0.70.7-0.7-0.8
Pavlov. Cond. intertrial magazine entries0.70.92.3-1.00.6-0.60.61.4-1.5-0.51.10.11.00.01.0-0.91.0-1.2-1.1-1.0-0.91.0-1.0-0.9
Pavlov. Cond. lever-magazine prob. diff.1.11.55.32.3-0.61.3-1.3-2.02.31.5-1.80.3-1.3-0.1-1.00.7-0.70.70.70.60.6-0.60.70.5
Pavlov. Cond. response bias0.70.93.31.8-0.71.3-1.3-1.61.81.4-1.40.5-0.8-0.3-0.60.3-0.30.30.30.20.3-0.30.30.2
Time in closed arm before self-admin0.10.10.60.40.30.1-0.10.6-0.0-0.30.8-0.7-0.40.5-0.30.1-0.10.3-0.00.10.1-0.20.00.2
Time in closed arm after self-admin0.50.52.0-1.40.3-0.80.80.9-0.9-1.01.3-0.60.00.6-0.10.4-0.80.40.40.20.5-0.40.30.5
Time in open arm before self-admin0.50.53.2-1.8-0.3-0.50.50.3-1.1-0.10.30.81.3-0.60.8-0.60.6-0.6-0.3-0.5-0.50.4-0.4-0.5
Time in open arm after self-admin1.11.22.70.6-1.11.1-1.1-0.70.11.2-1.21.31.0-1.41.1-1.01.7-0.9-1.1-0.9-1.00.9-1.0-1.4
Bone: periosteal estimation1.93.97.4-0.42.2-1.71.70.70.4-1.70.8-2.5-2.72.5-2.42.2-2.02.32.22.22.1-2.22.12.1
Bone: periosteal perimeter0.91.53.40.11.4-0.90.90.30.4-0.80.4-1.5-1.91.6-1.61.2-1.41.41.41.21.3-1.31.21.2
Bone: post-yield work4.46.012.2-0.83.0-2.22.21.30.1-2.41.7-3.2-3.43.5-3.02.7-2.42.62.52.42.4-2.52.52.3
Progressive ratio test 1 active lever presses1.01.13.3-1.41.6-1.51.51.8-1.6-1.31.4-0.80.40.70.5-0.20.4-0.5-0.6-0.3-0.50.5-0.4-0.5
Progressive ratio test 1 breakpoint1.01.13.6-1.41.4-1.31.31.9-1.8-1.31.6-0.70.50.60.6-0.40.6-0.6-0.8-0.5-0.60.7-0.6-0.6
Progressive ratio test 1 inactive lever presses0.30.30.7-0.50.6-0.80.80.10.0-0.4-0.3-0.5-0.30.3-0.50.7-0.50.60.40.80.6-0.60.70.3
Progressive ratio test 2 active lever presses1.51.65.5-1.42.3-2.12.12.0-1.3-1.81.9-1.7-0.61.4-0.20.7-0.30.30.30.30.2-0.20.30.1
Progressive ratio test 2 breakpoint1.41.55.1-1.52.1-1.81.82.3-1.7-1.72.0-1.4-0.11.00.40.10.2-0.3-0.2-0.2-0.30.3-0.3-0.4
Progressive ratio test 2 inactive lever presses1.61.97.2-1.12.7-2.42.41.6-0.7-1.80.7-1.9-1.01.5-0.61.2-0.60.70.61.10.7-0.70.90.2
Incentive Sensitization - Responses0.50.51.40.31.0-0.70.70.10.4-0.40.1-1.0-1.20.7-0.80.9-0.70.70.90.90.7-0.70.80.5
Incentive Sensitization - Breakpoint0.60.61.40.21.1-0.80.80.30.3-0.50.2-1.1-1.20.8-0.80.9-0.70.70.90.90.7-0.70.80.5
Sum of active levers in priming session hrs 5-62.12.06.82.6-1.32.2-2.2-1.41.22.1-2.01.30.0-1.30.8-1.10.4-1.0-0.8-1.1-1.31.1-1.0-0.9
Progressive ratio0.50.62.00.30.3-0.00.0-0.40.7-0.00.7-0.6-0.91.1-1.10.7-1.40.70.80.60.8-0.70.61.4
Food seeking constrained by brief footshock0.00.10.3-0.5-0.4-0.00.00.1-0.4-0.30.20.30.4-0.10.1-0.30.2-0.1-0.00.0-0.10.2-0.00.0
Seeking ratio, punishment vs. effort0.40.41.2-0.9-0.3-0.30.30.5-0.9-0.5-0.50.51.0-0.90.9-0.51.1-0.4-0.4-0.3-0.50.5-0.3-1.1
Retroperitoneal fat weight1.75.616.5-3.54.1-3.93.93.4-2.6-3.42.6-2.7-0.82.3-0.71.4-0.60.90.90.91.0-0.90.90.5
Reaction time number correct0.50.74.10.8-1.01.0-1.0-1.40.91.1-2.00.80.4-1.00.2-0.3-0.3-0.2-0.20.1-0.10.10.00.1
Reaction time mean minus median0.50.73.01.7-0.61.2-1.2-0.80.81.20.30.8-0.3-0.1-0.0-0.7-0.3-0.8-0.3-0.8-0.80.8-0.80.4
Reaction time mean minus median AUC0.81.11.81.3-1.01.3-1.3-0.80.41.30.21.30.5-0.80.6-1.20.4-1.3-0.8-1.4-1.31.3-1.3-0.5
Reaction time num false alarms0.40.62.7-1.3-0.6-0.10.10.3-1.1-0.10.20.71.6-0.91.0-0.90.4-0.7-0.7-0.7-0.60.7-0.8-0.5
Reaction time num false alarms AUC0.40.62.4-0.8-1.10.3-0.3-0.4-0.60.5-0.11.11.6-1.20.9-0.90.2-0.7-0.6-0.8-0.60.7-0.8-0.5
Reaction time trials correct on left0.50.74.10.8-1.01.0-1.0-1.40.91.1-2.00.80.4-1.00.2-0.3-0.3-0.2-0.20.1-0.10.10.00.1
Reaction time trials on left0.50.74.20.9-1.01.1-1.1-1.40.91.2-2.10.90.5-1.10.3-0.4-0.3-0.3-0.2-0.0-0.20.2-0.10.0
Reaction time mean0.20.31.10.60.30.2-0.20.2-0.10.40.60.50.2-0.10.4-0.60.4-1.0-0.7-0.9-1.00.9-0.9-0.3
Reaction time mean AUC0.20.31.00.50.40.2-0.20.3-0.20.40.60.40.2-0.00.3-0.60.3-1.0-0.7-0.8-1.00.9-0.9-0.3
Median of all reaction times0.10.10.40.30.6-0.20.20.2-0.00.10.30.1-0.10.20.0-0.10.2-0.4-0.3-0.3-0.50.3-0.4-0.2
Reaction time omissions0.81.12.40.6-1.01.1-1.1-0.5-0.11.10.31.61.1-1.01.0-1.40.5-1.4-0.7-1.4-1.41.4-1.3-0.4
Reaction time false alarm rate0.30.41.6-1.3-0.2-0.50.50.6-1.1-0.51.10.21.0-0.30.6-0.40.2-0.3-0.3-0.5-0.30.3-0.5-0.2
Reaction time premature initiation rate1.62.15.61.3-1.70.9-0.9-2.32.40.7-1.60.0-0.6-0.4-1.21.3-1.41.71.51.51.9-1.91.41.4
Reaction time premature initiations1.92.79.51.9-2.61.9-1.9-3.12.81.7-2.70.9-0.0-1.4-0.60.6-1.11.00.91.01.3-1.30.90.9
Std. dev. reaction times0.81.12.70.9-0.40.9-0.9-0.0-0.21.00.91.10.7-0.60.9-1.40.5-1.6-1.0-1.6-1.61.6-1.5-0.5
Reaction time trials completed0.50.74.20.9-1.01.1-1.1-1.40.91.2-2.10.90.5-1.10.3-0.4-0.3-0.3-0.2-0.0-0.20.2-0.10.0
Reaction time trials AUC0.40.53.60.7-0.80.8-0.8-1.30.81.0-1.90.70.4-0.90.2-0.2-0.4-0.2-0.10.1-0.10.10.10.1
Run reversals in cocaine runway, females2.32.24.8-0.70.3-0.90.9-0.60.8-1.00.3-1.3-1.31.1-1.81.9-1.81.92.21.81.9-1.91.92.0
Run reversals in cocaine runway, males0.30.30.8-0.6-0.1-0.10.10.7-0.9-0.30.60.30.8-0.20.6-0.70.3-0.7-0.7-0.6-0.60.6-0.6-0.4
Latency to leave start box in cocaine runway1.11.22.5-1.11.2-1.31.31.0-0.4-1.41.6-1.5-1.01.4-0.81.1-1.10.90.80.80.9-1.00.90.8
Latency to leave start box in cocaine runway, F0.10.10.3-0.10.3-0.30.30.10.2-0.30.2-0.5-0.50.4-0.30.5-0.60.40.40.40.4-0.40.40.2
Latency to leave start box in cocaine runway, M1.51.48.0-1.91.2-1.31.42.0-1.7-1.52.8-1.20.01.4-0.10.1-0.4-0.10.0-0.10.0-0.1-0.10.5
Std. dev. time between licks in bursts0.10.10.8-0.9-0.7-0.20.20.1-0.5-0.30.40.20.8-0.40.3-0.2-0.10.00.10.00.00.00.0-0.1
Total sessions with >9 infusions2.32.57.0-2.22.5-2.62.61.7-1.1-2.22.1-1.8-0.61.9-0.81.2-0.80.90.60.90.9-0.80.80.9
Short access day 1 total inactive lever presses1.31.54.3-1.92.0-2.12.11.5-1.0-1.70.9-1.5-0.41.2-0.51.0-0.30.70.60.90.7-0.70.80.1
Short access day 10 total inactive lever presses1.01.15.1-2.30.9-1.31.31.8-1.9-1.51.4-0.50.80.30.7-0.20.3-0.5-0.3-0.3-0.50.5-0.4-0.5
Short access day 1 total infusions1.92.06.5-1.72.5-2.62.51.5-0.9-1.91.1-1.6-0.61.5-0.81.1-0.80.80.61.00.8-0.80.80.8
Short access day 10 total infusions3.64.09.5-1.53.1-3.13.11.2-0.3-2.41.1-2.4-1.62.4-1.82.0-1.71.71.42.11.7-1.61.91.7
Short access total infusions2.22.57.1-1.62.6-2.72.61.2-0.6-1.90.9-1.8-1.01.8-1.21.4-1.21.10.91.51.1-1.11.31.2
Short access day 1 locomotion3.13.36.1-1.22.4-2.52.50.50.3-1.80.4-2.1-1.71.9-1.82.2-1.81.91.82.01.9-1.91.91.6
Short access day 10 total locomotion2.22.54.1-1.01.8-2.02.00.60.3-1.70.9-2.0-1.61.7-1.52.0-1.41.71.71.61.7-1.71.61.2
Short access total locomotion3.63.76.3-1.02.0-2.32.30.40.6-1.90.8-2.3-2.02.0-1.92.5-1.92.22.12.12.2-2.22.11.6
One hour access (0.3 mA shock)2.42.98.2-2.32.9-2.82.82.7-1.9-2.52.3-2.1-0.41.7-0.00.8-0.20.20.10.30.2-0.20.2-0.1
Compulsive drug intake2.02.08.00.8-2.82.3-2.2-1.90.81.9-2.11.71.0-2.00.6-0.80.5-0.4-0.5-0.4-0.40.4-0.4-0.5
One hour access (shock baseline)2.83.211.1-1.93.3-2.82.83.1-2.2-2.43.0-1.9-0.31.90.30.20.3-0.3-0.4-0.4-0.30.3-0.4-0.4
Social response proportion0.10.10.40.3-0.70.6-0.6-0.60.40.5-0.40.4-0.1-0.2-0.10.1-0.10.10.20.20.2-0.10.20.1
Social responses0.70.91.80.4-1.31.2-1.2-1.00.21.3-1.01.31.0-1.20.8-1.01.0-0.6-0.8-0.8-0.50.6-0.9-0.6
Social time0.40.61.60.2-0.80.7-0.7-0.5-0.10.8-0.31.31.0-0.90.7-0.90.3-0.8-0.9-0.9-0.70.9-0.9-0.5
Soleus weight1.02.89.6-2.92.2-2.42.43.1-2.9-2.12.1-1.10.90.80.9-0.21.0-0.3-0.8-0.6-0.40.4-0.6-1.1
Bone: stiffness0.81.33.91.20.40.2-0.2-0.91.50.2-0.3-0.8-2.01.2-1.71.2-1.41.31.41.21.2-1.11.31.4
Tibialis anterior weight3.311.338.55.7-3.54.0-4.0-6.06.24.0-5.31.7-2.1-1.1-2.21.4-1.62.11.61.92.0-1.91.81.5
Time to tail flick, vehicle, before self-admin2.02.14.20.21.0-0.70.7-0.31.0-0.90.3-1.6-1.81.6-1.81.7-2.01.52.01.61.6-1.61.72.0
Time to tail flick, vehicle, after self-admin1.11.23.4-0.4-0.2-0.30.3-0.50.6-0.61.0-0.8-1.01.1-1.41.1-1.81.21.61.11.2-1.31.21.8
Time to tail flick, test, before self-admin3.02.94.6-0.91.5-1.81.80.20.6-1.70.3-1.9-1.51.6-1.72.1-2.02.12.02.02.1-2.12.02.0
Time to tail flick, test, after self-admin0.10.10.4-0.2-0.30.2-0.20.2-0.30.20.20.20.3-0.10.2-0.40.3-0.2-0.6-0.2-0.30.3-0.3-0.2
Delta time to tail flick, vehicle, before/after SA0.10.10.5-0.5-0.60.1-0.1-0.0-0.2-0.00.70.10.30.1-0.1-0.1-0.10.1-0.2-0.10.1-0.1-0.10.2
Delta time to tail flick, test, before/after SA3.73.35.31.2-2.02.3-2.3-0.7-0.22.1-1.02.01.5-1.91.7-2.21.9-1.9-2.1-1.9-2.02.0-1.9-1.9
Tibia length0.61.77.42.7-0.41.4-1.4-1.72.51.3-1.8-0.3-1.90.3-1.10.9-0.70.80.50.90.7-0.80.80.7
Ambulatory time before self-admin0.70.84.42.10.00.8-0.8-1.31.61.1-1.50.2-1.0-0.3-0.40.4-0.40.50.40.20.3-0.30.20.3
Ambulatory time after self-admin0.10.20.60.80.5-0.00.0-0.10.60.1-0.2-0.6-0.70.2-0.30.4-0.30.50.40.20.2-0.30.30.2
Bone: tissue strength0.20.20.70.00.10.3-0.3-0.0-0.10.6-0.40.50.3-0.30.3-0.30.9-0.3-0.5-0.4-0.50.4-0.3-0.8
Total heroin consumption1.92.26.72.6-2.02.2-2.2-2.21.92.1-2.22.00.4-1.50.3-0.80.2-0.5-0.6-0.7-0.60.5-0.7-0.2
Bone: trabecular number1.11.74.20.50.9-0.40.4-0.51.2-0.3-0.2-1.2-2.11.3-1.81.7-1.61.41.61.61.4-1.41.61.6
Bone: trabecular spacing0.81.12.9-0.4-0.80.4-0.40.1-0.80.5-0.31.31.7-1.31.3-1.31.4-0.8-1.1-1.1-1.11.1-1.2-1.5
Bone: trabecular thickness0.30.41.7-0.21.3-1.01.00.9-0.4-0.70.8-0.9-0.40.8-0.30.4-0.30.10.20.20.2-0.20.10.4
Bone: trabecular tissue density2.23.27.8-1.80.8-0.70.72.3-2.8-0.62.10.61.9-0.52.0-1.81.7-2.2-1.9-2.2-2.22.2-2.0-1.6
Water consumed over 24 hours0.70.82.90.9-1.71.5-1.5-1.40.81.2-1.21.00.5-1.10.5-0.50.5-0.2-0.5-0.3-0.20.2-0.3-0.6
Number of responses in last shaping day0.10.10.5-0.50.2-0.30.3-0.3-0.00.4-0.70.10.2-0.30.10.20.10.10.00.20.1-0.10.1-0.2