Hub : Genes

Cyp7b1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr2_100638373_100669465 0.1 0.07 4.4e-06 0.04 0.04 0.06 0.05 2.7e-05 9.1e-06 3.1e-07 5.6e-06
2 NAcc mRNA stability Cyp7b1 0.03 0.03 1.1e-03 0.01 0.02 0.01 0.01 6.1e-03 1.8e-03 1.0e-02 7.6e-03
3 PL intron excision ratio chr2_100660904_100669465 0.08 0.06 3.8e-05 0.04 0.04 0.04 0.04 6.4e-05 2.9e-05 6.4e-05 1.6e-05
4 PL gene expression Cyp7b1 0.13 0.06 5.1e-15 0.07 0.1 0.09 0.09 1.2e-08 1.3e-10 7.7e-10 6.9e-10
5 NAcc intron excision ratio chr2_100638373_100669465 0.05 0.04 1.0e-04 0.03 0.03 0.03 0.03 1.6e-04 2.2e-04 2.5e-04 1.7e-04
6 NAcc intron excision ratio chr2_100660904_100669465 0.05 0.04 8.1e-05 0.04 0.03 0.03 0.03 4.0e-05 3.2e-04 2.6e-04 7.7e-05
7 PL alternative polyA NM_019138.1 0.03 0.02 5.0e-04 0.02 0.01 0 0.01 6.6e-03 1.6e-02 8.1e-02 3.0e-02
8 PL alternative polyA XM_039101794.1 0.03 0.02 4.6e-04 0.01 0.01 0 0.01 1.3e-02 1.1e-02 7.6e-02 2.9e-02
9 Brain gene expression Cyp7b1 0.3 0.13 0.0e+00 0.2 0.19 0.19 0.2 1.6e-18 2.0e-17 1.8e-17 6.8e-18
10 BLA gene expression Cyp7b1 0.46 0.16 0.0e+00 0.22 0.24 0.25 0.25 5.0e-12 2.7e-13 2.2e-13 7.3e-14
11 NAcc gene expression Cyp7b1 0.11 0.06 3.1e-14 0.09 0.1 0.1 0.1 1.3e-10 1.7e-11 1.2e-11 1.5e-11
12 pVTA gene expression Cyp7b1 0.08 0.08 2.3e-03 0.01 0.06 0.06 0.08 7.5e-02 1.6e-03 1.9e-03 3.4e-04
13 Brain mRNA stability Cyp7b1 0.07 0.05 4.3e-05 0.03 0.03 0.02 0.03 3.7e-04 6.8e-04 5.7e-03 2.1e-03
14 Liver alternative polyA NM_019138.1 0.05 0.04 2.0e-03 0.01 0.01 0.01 0 4.8e-02 3.3e-02 2.2e-02 8.2e-02
15 Liver mRNA stability Cyp7b1 0.15 0.1 1.9e-10 0.05 0.06 0.04 0.05 3.6e-06 2.4e-07 1.1e-05 2.3e-06
16 Liver alternative polyA XM_039101794.1 0.06 0.04 6.8e-04 0 0.01 0.01 0 2.2e-01 5.1e-02 2.6e-02 1.2e-01
17 Liver gene expression Cyp7b1 0.98 0.01 0.0e+00 0.32 0.38 0.39 0.39 4.2e-36 1.1e-44 2.5e-45 6.2e-46

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density1.62.64.31.6-1.71.5-1.81.9-1.91.91.91.9-1.92.0-2.02.10.40.5-0.2-0.2
Area under the delay curve0.70.71.4-1.11.0-0.90.7-1.21.2-1.1-0.9-1.10.6-0.90.7-0.60.0-0.0-0.10.2
BMI with tail2.06.48.9-3.02.8-2.92.6-2.82.8-2.7-2.6-2.82.3-2.52.5-2.1-2.2-2.22.0-1.8
BMI without tail2.45.06.2-2.52.4-2.52.5-2.02.0-1.9-2.2-2.22.2-2.11.4-2.4-2.5-2.52.4-2.1
Body weight2.29.212.8-3.63.4-3.43.2-3.43.4-3.4-3.2-3.43.0-3.23.3-2.7-2.0-2.22.0-1.6
Weight adjusted by age0.80.91.8-1.21.0-0.81.1-1.01.0-1.0-1.0-0.71.4-1.01.0-1.2-0.6-0.70.5-0.3
Bone surface0.10.20.7-0.0-0.30.1-0.40.5-0.50.50.50.5-0.50.6-0.50.8-0.4-0.40.6-0.7
Bone volume0.20.41.00.5-0.60.5-0.70.8-0.80.80.80.8-0.70.8-0.71.00.10.10.1-0.2
Breakpoint value in progressive ratio session0.50.50.8-0.80.8-0.90.6-0.50.5-0.7-0.6-0.70.6-0.50.4-0.5-0.9-0.90.9-0.9
Number of licking bursts2.32.84.5-2.11.8-1.71.8-1.81.8-1.8-1.8-1.81.9-1.81.9-1.8-1.0-1.10.9-0.6
Context. condit. distance diff. score0.50.61.2-0.80.7-0.50.7-0.90.9-0.9-0.8-0.90.9-0.81.1-0.80.30.2-0.40.6
Locomotion velocity, session 10.50.51.0-0.70.7-0.80.7-0.60.6-0.6-0.6-0.60.6-0.60.4-0.6-1.0-1.01.0-0.9
Locomotion distance, session 10.00.00.0-0.00.2-0.10.1-0.20.2-0.2-0.2-0.20.0-0.2-0.1-0.1-0.0-0.0-0.10.1
Locomotion velocity, session 22.63.03.9-1.92.0-2.01.9-1.81.8-1.8-1.9-1.81.6-1.81.3-1.8-1.5-1.61.4-1.1
Locomotion distance, session 20.10.20.5-0.40.3-0.40.3-0.10.1-0.1-0.2-0.10.1-0.1-0.1-0.2-0.7-0.70.7-0.7
Locomotion velocity, session 30.80.91.5-0.81.0-1.01.1-1.01.0-1.0-1.1-1.01.2-1.21.0-1.2-0.7-0.60.5-0.3
Locomotion distance, session 30.70.81.2-0.90.9-0.91.0-0.80.8-0.8-0.9-0.81.0-0.90.8-0.9-1.1-1.00.9-0.8
Stereotopy head waving bouts, day 30.10.20.30.4-0.50.4-0.50.4-0.40.40.40.4-0.40.4-0.20.40.50.5-0.50.4
Stereotopy head waving duration, day 30.30.30.50.6-0.60.6-0.70.6-0.60.60.70.6-0.70.6-0.60.70.50.5-0.40.3
Locomotion velocity, session 71.51.62.11.1-1.41.4-1.51.4-1.41.41.51.4-1.31.4-1.11.50.91.0-0.90.6
Locomotion distance, session 71.41.82.71.0-1.51.4-1.51.6-1.61.61.61.6-1.41.6-1.41.60.40.5-0.2-0.0
Stereotopy head waving bouts, day 70.60.71.2-0.40.6-0.50.7-1.01.0-1.0-0.9-1.00.7-0.90.9-0.80.60.6-0.91.1
Stereotopy head waving duration, day 70.40.50.8-0.50.7-0.60.7-0.90.9-0.9-0.9-0.90.7-0.90.8-0.80.10.1-0.40.6
Locomotion velocity, session 81.31.52.3-1.21.3-1.21.4-1.51.5-1.5-1.5-1.51.3-1.51.2-1.5-0.3-0.40.20.1
Locomotion distance, session 81.31.92.8-1.41.5-1.31.5-1.61.6-1.6-1.6-1.61.6-1.71.6-1.7-0.3-0.40.10.2
Degree of sensitization distance3.43.44.81.6-2.01.9-2.12.1-2.12.12.22.1-2.22.2-2.12.20.80.8-0.50.1
Degree of sensitization stereotypy2.62.84.2-1.41.7-1.51.8-2.12.1-2.1-2.0-2.11.9-2.12.0-2.00.10.0-0.50.9
Conditioned locomotion1.92.33.61.9-1.61.6-1.61.2-1.21.21.41.3-1.51.3-1.31.41.91.8-1.71.5
Cocaine response after cond. corrected0.20.20.30.3-0.40.4-0.40.6-0.60.60.50.6-0.30.6-0.40.5-0.4-0.20.3-0.3
Cocaine response after cond. not corrected0.20.20.30.2-0.40.3-0.40.6-0.60.60.50.6-0.30.6-0.40.5-0.5-0.30.4-0.5
Cocaine response before conditioning0.10.10.30.0-0.20.1-0.40.4-0.40.40.40.4-0.50.4-0.40.5-0.3-0.30.4-0.5
Saline control response0.40.50.8-0.70.8-0.80.8-0.80.8-0.8-0.8-0.80.8-0.80.9-0.6-0.5-0.60.5-0.4
Bone: connectivity density1.82.85.31.5-1.61.4-1.81.9-1.91.91.91.9-2.12.0-2.32.2-0.10.10.3-0.6
Bone: cortical apparent density1.01.31.9-1.01.3-1.21.3-1.41.4-1.4-1.4-1.41.3-1.31.3-1.3-0.4-0.50.3-0.1
Bone: cortical area0.50.71.9-0.40.2-0.00.4-0.70.7-0.7-0.6-0.71.0-0.81.4-0.71.31.0-1.21.4
Bone: cortical porosity0.30.30.50.4-0.60.5-0.50.7-0.70.70.60.7-0.50.6-0.60.50.00.10.1-0.2
Bone: cortical porosity0.10.10.20.3-0.40.4-0.30.4-0.40.40.30.4-0.20.3-0.30.10.30.3-0.20.1
Bone: cortical thickness0.61.13.90.7-0.81.0-0.60.3-0.30.30.40.30.10.20.50.22.01.8-1.92.0
Bone: cortical thickness1.21.42.6-1.61.3-1.31.3-1.11.1-1.1-1.2-1.11.3-1.11.2-1.1-1.1-1.11.1-0.9
Bone: cortical tissue density1.11.42.0-1.01.3-1.31.4-1.41.4-1.4-1.4-1.41.3-1.41.3-1.4-0.6-0.70.5-0.3
Condit. Reinf. active minus inactive responses0.00.00.1-0.10.2-0.10.2-0.20.2-0.2-0.2-0.20.2-0.20.1-0.30.20.1-0.20.3
Condit. Reinf. active-inactive response ratio0.00.00.1-0.20.2-0.20.1-0.10.1-0.1-0.0-0.1-0.1-0.0-0.10.0-0.3-0.30.3-0.3
Condit. Reinf. active responses0.10.20.3-0.30.5-0.40.5-0.40.4-0.4-0.5-0.40.4-0.40.2-0.5-0.3-0.40.3-0.3
Condit. Reinf. inactive responses0.30.40.6-0.50.7-0.70.7-0.50.5-0.5-0.7-0.50.7-0.60.4-0.8-0.7-0.70.7-0.6
Incentive salience index mean0.20.20.3-0.40.5-0.40.5-0.50.5-0.5-0.5-0.50.5-0.50.4-0.6-0.1-0.10.00.1
Condit. Reinf. lever presses0.30.41.0-0.70.7-0.70.7-0.50.5-0.5-0.5-0.50.5-0.50.2-0.6-1.0-1.00.9-0.9
Condit. Reinf. active minus inactive responses0.40.40.9-0.90.7-0.70.6-0.80.8-0.8-0.7-0.80.7-0.60.9-0.6-0.4-0.30.1-0.0
Condit. Reinf. active-inactive response ratio0.40.40.7-0.80.7-0.80.5-0.50.5-0.5-0.5-0.60.4-0.40.6-0.4-0.8-0.70.7-0.7
Condit. Reinf. active responses0.20.20.6-0.80.5-0.50.4-0.50.5-0.5-0.5-0.50.5-0.40.8-0.4-0.3-0.20.1-0.0
Condit. Reinf. inactive responses0.10.10.4-0.30.10.00.2-0.30.3-0.3-0.2-0.30.5-0.20.6-0.20.30.3-0.50.6
Condit. Reinf. lever presses0.30.40.60.7-0.70.7-0.70.8-0.80.80.70.7-0.60.7-0.50.60.40.4-0.20.1
Condit. Reinf. lever reinforcers received0.10.10.5-0.70.4-0.40.3-0.40.4-0.4-0.3-0.40.4-0.30.6-0.3-0.3-0.20.1-0.1
Conditioned reinforcement - actives0.40.41.01.0-0.60.6-0.60.7-0.70.60.60.6-0.70.6-0.70.50.60.4-0.40.3
Conditioned reinforcement - inactives0.20.21.01.0-0.50.4-0.30.6-0.60.50.40.6-0.50.3-0.90.00.10.2-0.0-0.0
Conditioned locomotion0.60.71.6-1.10.9-0.91.0-0.80.8-0.7-1.0-0.91.1-1.00.8-1.2-0.1-0.60.2-0.0
Patch foraging indifference point 0 sec0.20.41.40.10.1-0.00.3-0.50.5-0.4-0.5-0.30.5-0.60.5-0.51.00.9-1.01.2
Patch foraging indifference point AUC0.10.10.40.3-0.10.2-0.10.3-0.30.20.20.2-0.20.1-0.2-0.1-0.2-0.40.5-0.7
Delay disc. indifference point, 0s delay0.40.40.8-0.50.4-0.20.5-0.70.7-0.7-0.6-0.50.7-0.70.8-0.60.70.5-0.70.9
Delay disc. indifference point, 16s delay0.20.20.5-0.1-0.00.0-0.3-0.10.1-0.20.1-0.2-0.50.2-0.20.50.70.6-0.70.6
Delay disc. indifference point, 2s delay0.60.61.1-0.60.7-0.70.5-1.01.0-0.9-0.8-1.00.5-0.70.9-0.40.70.7-0.81.0
Delay disc. indifference point, 24s delay0.80.81.70.6-0.80.8-1.10.8-0.80.71.00.7-1.31.0-1.01.30.70.8-0.60.4
Delay disc. indifference point, 4s delay1.71.82.3-1.51.5-1.41.5-1.51.5-1.5-1.5-1.41.3-1.50.8-1.5-1.1-1.11.0-0.7
Delay disc. indifference point, 8s delay0.70.71.1-1.01.0-1.00.8-1.01.0-1.0-0.9-0.90.7-0.90.7-0.7-0.5-0.50.4-0.3
Indifference point function ln k1.11.52.4-1.31.4-1.51.3-1.31.3-1.1-1.2-1.11.0-1.10.8-1.0-1.5-1.41.4-1.2
Indifference point function log k1.11.52.4-1.31.4-1.51.3-1.31.3-1.1-1.2-1.11.0-1.10.8-1.0-1.5-1.41.4-1.2
Patch foraging total patch changes 0 sec0.30.50.9-0.30.5-0.40.7-0.80.8-0.7-0.8-0.61.0-0.90.7-0.90.50.3-0.50.7
Patch foraging total patch changes 12 sec0.00.10.30.1-0.10.1-0.0-0.20.2-0.2-0.00.1-0.0-0.10.30.00.60.4-0.40.4
Patch foraging total patch changes 18 sec0.10.10.30.4-0.10.30.1-0.00.0-0.0-0.1-0.00.2-0.20.1-0.30.60.3-0.30.3
Patch foraging total patch changes 24 sec0.10.10.30.4-0.40.4-0.40.3-0.30.30.40.5-0.50.3-0.40.40.20.1-0.0-0.1
Patch foraging total patch changes 6 sec0.20.30.6-0.20.5-0.40.6-0.70.7-0.7-0.7-0.60.6-0.80.5-0.60.2-0.0-0.10.2
Patch foraging time to switch 0 sec0.30.40.9-0.90.5-0.30.4-0.80.8-0.9-0.6-0.70.5-0.50.9-0.50.20.2-0.50.6
Patch foraging water rate 0 sec0.10.20.90.7-0.30.2-0.20.5-0.50.70.30.4-0.30.3-0.90.2-0.3-0.20.5-0.5
Patch foraging water rate 12 sec1.11.62.91.2-1.31.2-1.11.6-1.61.71.41.6-1.11.4-1.71.1-0.3-0.20.6-0.9
Patch foraging water rate 18 sec0.81.12.51.1-1.10.9-0.81.4-1.41.51.11.4-0.81.0-1.60.7-0.4-0.30.6-0.8
Patch foraging water rate 24 sec0.50.72.30.3-0.30.1-0.40.7-0.70.90.60.7-0.60.6-1.00.7-1.2-1.01.4-1.5
Patch foraging water rate 6 sec0.20.31.2-0.20.2-0.30.50.2-0.20.3-0.20.10.5-0.2-0.4-0.5-0.9-0.91.1-1.1
Seeking ratio, delayed vs. immediate footshock2.52.94.32.0-1.61.7-2.01.6-1.61.71.71.2-1.81.8-1.42.11.71.8-1.61.4
Distance traveled before self-admin3.43.64.9-2.12.1-2.22.1-2.02.0-1.9-2.1-2.02.0-2.01.9-1.9-1.5-1.61.3-1.1
Distance traveled after self-admin3.03.34.9-1.72.1-2.12.0-2.12.1-2.1-2.2-2.21.8-2.12.2-1.9-0.6-0.80.5-0.2
Extensor digitorum longus weight6.324.831.2-5.55.5-5.55.6-5.25.2-5.2-5.4-5.25.4-5.34.7-5.3-4.0-4.33.7-2.9
Bone: elastic displacement2.93.35.01.9-2.01.9-1.92.2-2.22.22.12.2-1.92.1-2.11.80.60.8-0.40.1
Bone: elastic work1.11.42.11.2-1.31.3-1.31.4-1.41.41.31.4-1.21.3-1.31.30.60.7-0.40.2
Bone: endosteal estimation1.42.94.8-2.21.9-1.91.8-1.71.7-1.7-1.7-1.71.7-1.71.6-1.5-1.6-1.71.6-1.4
Bone: endosteal perimeter1.42.96.0-1.71.6-1.51.7-2.12.1-2.1-1.9-2.12.0-2.02.4-1.80.3-0.0-0.40.7
Epididymis fat weight4.610.717.6-4.23.6-3.63.5-3.73.7-3.7-3.5-3.63.2-3.53.7-3.2-1.9-2.31.8-1.4
Delta time in closed arm before/after self-admin0.40.40.70.7-0.60.4-0.70.6-0.60.60.70.5-0.80.7-0.80.80.10.2-0.0-0.1
Delta time in open arm before/after self-admin1.21.21.8-1.31.2-1.11.1-1.31.3-1.2-1.1-1.11.2-1.11.3-0.9-0.8-0.80.7-0.6
Diff in mean of infusions in LGA sessions0.50.61.20.9-1.01.0-0.61.1-1.11.00.81.0-0.40.7-0.90.10.40.4-0.30.3
Delay discount exponential model param0.60.61.21.0-0.90.9-0.61.1-1.11.10.81.0-0.60.8-0.70.40.10.10.0-0.1
Extinction: sum of active levers before priming2.12.14.4-2.11.8-2.01.0-1.81.8-1.9-1.3-1.80.9-1.22.0-0.4-0.8-0.80.7-0.6
Active lever presses in extinction session 60.10.10.30.00.3-0.30.3-0.20.2-0.3-0.2-0.30.4-0.30.2-0.4-0.5-0.50.5-0.5
Bone: final force1.32.13.6-1.91.6-1.51.5-1.61.6-1.6-1.6-1.61.7-1.61.8-1.3-0.8-0.90.7-0.5
Bone: final moment1.11.83.1-1.81.4-1.41.4-1.51.5-1.5-1.4-1.51.6-1.41.7-1.2-0.6-0.80.6-0.4
Food consumed during 24 hour testing period4.04.86.0-2.52.4-2.42.4-2.22.2-2.2-2.3-2.22.4-2.22.1-2.2-2.1-2.11.8-1.4
Glucose0.60.81.2-1.11.0-1.01.0-0.90.9-0.9-1.0-1.01.1-1.01.0-1.0-0.4-0.70.6-0.5
Heart weight0.10.10.2-0.50.3-0.5-0.1-0.40.4-0.5-0.1-0.2-0.50.00.10.5-0.2-0.30.1-0.2
Delay discount hyperbolic model param0.70.71.41.1-1.01.0-0.81.2-1.21.11.01.1-0.70.9-0.80.60.20.2-0.1-0.0
Intermittent access intake day 1-15 change1.01.01.7-0.91.2-1.11.2-0.90.9-0.9-1.2-1.31.3-1.10.9-1.2-0.5-0.80.5-0.4
Intermittent access intake escalation0.40.40.9-0.10.8-0.70.8-0.50.5-0.4-0.8-0.90.9-0.80.3-0.9-0.2-0.50.3-0.2
Intermittent access intake escalation 20.30.20.70.30.5-0.50.7-0.30.3-0.1-0.6-0.60.8-0.70.3-0.9-0.1-0.40.2-0.1
Intermitt. access day 1 inactive lever presses0.20.21.00.7-0.30.1-0.50.3-0.30.40.40.2-1.00.5-0.90.60.20.2-0.10.0
Intermitt. access day 15 inactive lever presses0.50.51.41.0-0.60.6-0.80.8-0.80.80.70.6-1.00.6-1.20.70.20.4-0.10.0
Intermitt. access escalation Index0.30.30.70.5-0.60.6-0.70.4-0.40.40.60.5-0.80.6-0.60.80.20.5-0.20.2
Intermittent access day 1 total infusions0.30.31.00.8-0.50.5-0.40.6-0.60.60.40.6-0.60.4-1.00.10.70.3-0.60.5
Intermittent access day 15 total infusions0.20.21.10.9-0.20.3-0.00.5-0.50.60.10.2-0.20.0-1.0-0.30.60.1-0.40.4
Intermittent access terminal intake (last 3 days)0.30.31.40.10.6-0.50.8-0.30.3-0.3-0.7-0.50.5-0.8-0.4-1.20.1-0.5-0.00.1
Intermittent access total infusions0.10.21.10.7-0.20.2-0.10.3-0.30.30.10.2-0.40.0-1.0-0.20.50.1-0.40.4
Intermittent access day 1 locomotion0.60.61.2-0.71.0-0.90.9-0.80.8-0.8-1.0-1.10.9-0.90.7-1.0-0.3-0.60.3-0.2
Intermittent access day 15 total locomotion0.90.92.4-0.61.1-0.91.3-0.90.9-0.8-1.2-1.11.3-1.20.7-1.6-0.2-0.80.3-0.1
Intermittent access total locomotion0.81.01.9-0.71.2-1.11.2-1.01.0-0.9-1.2-1.31.1-1.20.7-1.4-0.3-0.80.3-0.1
Intermittent access standard deviation0.70.72.7-0.40.9-0.91.2-0.50.5-0.5-1.1-0.91.2-1.10.2-1.6-0.3-0.70.4-0.2
Left kidney weight0.00.00.30.1-0.0-0.0-0.20.0-0.0-0.10.10.0-0.50.1-0.00.40.20.1-0.20.1
Right kidney weight0.41.32.2-1.51.3-1.31.1-1.41.4-1.5-1.3-1.30.9-1.21.4-0.9-0.1-0.40.2-0.0
Cocaine induced anxiety0.10.10.20.4-0.40.4-0.30.4-0.40.40.40.4-0.20.4-0.10.30.40.3-0.30.3
Post-drug Anxiety0.60.70.91.0-1.01.0-0.91.0-1.01.00.91.0-0.70.8-0.80.70.60.6-0.50.4
Baseline Anxiety0.40.40.90.9-0.70.7-0.60.7-0.70.70.60.7-0.70.5-0.90.50.30.4-0.10.1
Tail length0.61.83.6-1.41.3-1.31.6-1.41.4-1.3-1.6-1.31.7-1.61.3-1.9-0.4-0.60.4-0.1
Length with tail0.83.06.4-1.81.8-1.71.7-2.12.1-2.1-2.0-2.02.0-2.02.5-1.60.1-0.1-0.20.5
Length without tail0.51.24.0-1.00.9-0.80.5-1.41.4-1.5-1.0-1.20.8-1.02.0-0.20.90.7-1.01.1
Times rat made contact with spout3.43.96.5-2.32.0-1.92.2-2.22.2-2.2-2.2-2.22.5-2.32.5-2.2-0.7-0.90.5-0.1
Lifetime Intake0.20.31.30.8-0.30.4-0.20.5-0.50.40.30.4-0.50.1-1.1-0.10.60.2-0.50.4
Liver weight, left3.96.210.2-3.22.7-2.62.8-2.52.5-2.5-2.6-2.42.7-2.52.3-2.6-2.2-2.21.9-1.5
Liver weight, right1.72.83.9-1.71.9-1.81.9-2.02.0-2.0-2.0-1.91.8-2.01.6-1.9-0.9-0.90.6-0.3
Locomotor activity1.22.03.0-1.71.6-1.71.4-1.61.6-1.6-1.4-1.41.2-1.31.5-1.1-1.1-1.21.1-0.9
Locomotor testing distance1.52.63.8-1.91.8-1.81.6-1.91.9-1.9-1.7-1.71.6-1.61.8-1.3-1.1-1.21.0-0.8
Locomotor testing rearing0.00.10.3-0.20.2-0.10.0-0.40.4-0.4-0.1-0.20.1-0.10.60.10.10.0-0.10.1
Locomotion in novel chamber0.20.20.7-0.20.4-0.50.5-0.50.5-0.7-0.6-0.50.6-0.50.8-0.60.10.0-0.20.3
Locomotion in novel chamber post-restriction0.40.41.40.9-0.40.3-0.80.3-0.30.20.50.2-1.20.5-0.51.00.70.7-0.70.6
Fecal boli incidents, locomotor time 10.80.91.8-1.11.1-1.00.6-0.90.9-1.0-0.6-1.10.1-0.50.6-0.0-1.3-1.31.3-1.3
Change in fecal boli incidents, locomotor task0.60.61.10.1-1.01.1-0.81.0-1.00.80.80.9-0.30.9-0.20.60.80.8-0.70.7
Time >=10cm from walls, locomotor time 10.10.10.3-0.4-0.10.1-0.10.2-0.20.20.20.1-0.20.2-0.00.3-0.4-0.40.5-0.6
Bouts of movement, locomotor time 10.10.10.5-0.10.2-0.2-0.2-0.10.1-0.20.1-0.1-0.60.2-0.30.5-0.6-0.50.6-0.7
Total resting periods, locomotor time 10.10.10.5-0.00.1-0.1-0.2-0.10.1-0.10.2-0.1-0.70.2-0.40.5-0.5-0.50.6-0.7
Rest time, locomotor task time 10.70.82.9-0.60.8-0.80.5-0.50.5-0.6-0.4-0.6-0.1-0.30.1-0.1-1.6-1.41.6-1.7
Distance moved, locomotor task time 10.40.41.8-0.1-0.00.10.3-0.30.3-0.1-0.3-0.10.7-0.40.5-0.71.10.9-1.21.4
Vertical activity count, locomotor time 10.70.83.70.1-0.20.20.2-0.30.3-0.0-0.4-0.10.6-0.50.3-0.81.61.4-1.71.9
Time >=10cm from walls, locomotor time 20.00.10.7-0.8-0.10.1-0.10.0-0.00.20.1-0.0-0.20.2-0.10.2-0.1-0.10.1-0.1
Bouts of movement, locomotor time 21.41.53.01.7-1.11.4-1.10.9-0.90.80.90.9-1.20.9-1.10.91.71.6-1.71.6
Total resting periods, locomotor time 21.01.12.51.6-0.91.2-0.90.7-0.70.60.70.7-1.00.7-1.00.61.41.3-1.41.4
Rest time, locomotor task time 20.30.31.60.10.20.00.00.1-0.1-0.20.10.1-0.40.1-0.40.2-1.1-1.11.2-1.3
Distance moved, locomotor task time 20.30.41.40.5-0.50.4-0.40.2-0.20.50.30.4-0.10.2-0.10.21.21.1-1.21.2
Vertical activity count, locomotor time 20.10.10.40.10.2-0.20.3-0.40.4-0.1-0.4-0.30.4-0.5-0.0-0.50.50.4-0.50.6
Light reinforcement 11.42.64.3-2.01.8-1.91.5-2.12.1-2.1-1.7-1.71.5-1.61.9-1.2-0.9-1.00.7-0.5
Light reinforcement 23.24.37.7-1.92.1-1.82.0-2.62.6-2.6-2.4-2.52.3-2.42.8-2.20.40.1-0.61.1
Bone: marrow area1.43.04.8-2.21.9-2.01.8-1.61.6-1.6-1.7-1.61.7-1.61.5-1.5-1.7-1.81.7-1.5
Bone: maximum diameter0.71.33.4-1.10.9-0.81.1-1.31.3-1.3-1.2-1.31.4-1.31.9-1.20.60.3-0.60.8
Bone: maximum force1.11.92.9-1.71.5-1.51.4-1.51.5-1.5-1.5-1.51.5-1.51.7-1.2-0.6-0.80.6-0.4
Bone: maximum moment0.81.52.5-1.61.3-1.31.3-1.31.3-1.3-1.3-1.31.4-1.31.5-1.1-0.5-0.70.6-0.4
Mean time between licks in bursts0.50.73.3-0.30.6-0.80.5-0.20.2-0.2-0.3-0.20.0-0.3-0.2-0.2-1.4-1.51.7-1.8
Mean num. licks in bursts0.40.50.80.9-0.70.8-0.70.6-0.60.60.60.6-0.50.6-0.50.60.80.8-0.80.8
Cd content in liver1.11.32.8-1.21.1-1.21.1-0.70.7-0.7-0.9-0.81.0-0.80.6-0.9-1.7-1.61.6-1.5
Co content in liver1.61.82.5-1.61.4-1.51.4-1.31.3-1.3-1.3-1.31.4-1.31.5-1.3-1.3-1.31.3-1.1
Cu content in liver0.00.00.10.0-0.20.2-0.20.1-0.1-0.00.20.2-0.20.10.10.30.30.1-0.1-0.0
Fe content in liver0.60.82.50.8-0.60.8-0.70.2-0.20.20.40.3-0.60.3-0.10.61.61.5-1.61.5
K content in liver0.20.20.50.4-0.40.5-0.50.4-0.40.30.40.3-0.50.5-0.40.50.50.7-0.70.7
Mg content in liver0.30.30.50.3-0.50.5-0.60.6-0.60.50.70.6-0.70.7-0.70.7-0.10.10.0-0.1
Mn content in liver0.10.10.30.3-0.20.1-0.20.2-0.20.30.30.3-0.50.2-0.40.4-0.1-0.20.3-0.4
Na content in liver1.11.12.3-0.90.9-0.70.9-1.31.3-1.3-1.1-1.31.1-1.21.5-1.00.50.5-0.91.2
Rb content in liver0.91.21.61.1-1.21.2-1.21.3-1.31.11.21.2-1.11.2-1.01.10.80.8-0.60.5
Se content in liver0.30.41.30.5-0.60.7-0.60.3-0.30.20.50.4-0.70.4-0.00.61.11.0-1.01.0
Sr content in liver1.41.23.00.5-0.60.4-0.81.0-1.01.01.11.0-1.31.1-1.51.2-1.3-1.11.4-1.7
Zn content in liver0.50.52.3-0.40.1-0.20.00.3-0.30.20.20.4-0.30.4-0.40.3-1.5-1.31.4-1.5
Bone: minimum diameter0.20.30.8-0.10.2-0.10.4-0.50.5-0.5-0.5-0.50.6-0.60.9-0.60.80.6-0.70.8
Time in familiar zone, hab. session 10.00.00.10.1-0.10.2-0.20.1-0.10.10.20.1-0.20.2-0.20.10.20.2-0.10.1
Time in novel zone, hab. session 10.20.20.3-0.40.5-0.50.5-0.50.5-0.5-0.5-0.50.6-0.50.5-0.5-0.4-0.30.2-0.1
Total zone transitions, hab. session 10.20.30.6-0.70.5-0.50.5-0.40.4-0.4-0.4-0.40.3-0.30.2-0.3-0.8-0.70.7-0.7
Total locomotion distance, hab. session 10.10.20.4-0.60.5-0.50.4-0.50.5-0.5-0.4-0.50.3-0.40.3-0.4-0.3-0.30.2-0.2
Locomotion velocity, hab. session 10.30.40.7-0.80.7-0.70.6-0.60.6-0.6-0.6-0.60.5-0.50.5-0.5-0.6-0.60.5-0.5
Time in familiar zone, hab. session 20.40.40.70.6-0.70.6-0.70.8-0.80.80.80.8-0.70.8-0.80.70.10.00.2-0.3
Time in novel zone, hab. session 20.10.10.20.3-0.20.2-0.30.3-0.30.30.30.3-0.40.3-0.50.4-0.2-0.00.0-0.1
Total zone transitions, hab. session 20.50.61.0-0.80.9-0.80.9-0.90.9-0.9-0.9-0.90.9-0.90.8-1.0-0.2-0.30.20.0
Total locomotion distance, hab. session 20.10.10.2-0.40.4-0.30.4-0.40.4-0.4-0.4-0.40.4-0.40.3-0.50.0-0.10.10.0
Locomotion velocity, hab. session 20.20.20.4-0.50.5-0.40.5-0.50.5-0.5-0.5-0.50.5-0.50.5-0.60.1-0.1-0.00.1
Novel to familiar place preference ratio2.02.12.61.6-1.61.6-1.61.5-1.51.51.51.5-1.51.5-1.41.51.21.3-1.21.0
Novelty place preference1.71.82.21.5-1.51.4-1.51.4-1.41.41.41.4-1.41.4-1.31.41.01.1-1.00.8
Time in novel zone, NPP test1.51.62.11.4-1.41.4-1.41.2-1.21.21.31.2-1.31.2-1.11.31.21.3-1.21.1
Total zone transitions, NPP test0.10.10.1-0.30.3-0.30.3-0.30.3-0.3-0.3-0.30.2-0.30.1-0.3-0.2-0.30.3-0.2
Total locomotion distance, NPP test0.10.20.3-0.50.5-0.40.5-0.40.4-0.4-0.5-0.40.5-0.50.4-0.5-0.1-0.30.2-0.1
Locomotion velocity, NPP test0.00.00.1-0.20.0-0.0-0.00.1-0.10.10.10.1-0.10.1-0.10.0-0.2-0.30.3-0.4
Intraocular pressure2.53.54.9-2.02.1-2.21.7-1.91.9-1.8-1.7-1.91.4-1.71.4-1.1-2.1-2.12.2-2.0
Delta distance traveled before/after self-admin0.60.61.50.9-0.80.9-0.50.6-0.60.60.40.6-0.30.3-0.20.11.21.2-1.21.2
Delta ambulatory time before/after self-admin0.90.91.41.2-1.11.1-0.91.1-1.11.00.80.9-0.90.8-0.70.51.11.1-1.11.0
Parametrial fat weight2.65.07.6-2.42.3-2.22.6-2.32.3-2.3-2.4-2.22.8-2.52.5-2.5-1.7-1.81.5-1.1
Pavlov. Cond. lever latency0.10.10.40.3-0.40.4-0.30.3-0.30.30.20.3-0.10.20.10.20.60.6-0.50.5
Pavlov. Cond. magazine entry latency0.81.04.3-0.30.4-0.60.20.1-0.10.10.00.1-0.40.1-0.90.1-1.9-1.81.9-2.1
Pavlov. Cond. change in total contacts1.31.41.7-1.01.3-1.31.3-1.31.3-1.3-1.3-1.31.1-1.30.9-1.3-1.1-1.10.9-0.7
Pavlov. Cond. index score1.31.64.1-1.21.3-1.41.2-0.90.9-0.9-1.0-0.90.7-0.90.3-0.8-2.0-1.91.9-1.8
Pavlov. Cond. latency score0.91.12.7-1.01.1-1.21.0-0.80.8-0.8-0.8-0.80.6-0.80.2-0.7-1.6-1.61.5-1.4
Pavlov. Cond. lever contacts0.70.92.3-0.80.9-1.00.8-0.60.6-0.6-0.7-0.60.4-0.60.0-0.6-1.5-1.51.4-1.4
Pavlov. Cond. magazine entry number1.51.84.71.2-1.41.5-1.20.9-0.90.91.00.9-0.71.0-0.30.92.22.1-2.12.0
Pavlov. Cond. intertrial magazine entries0.50.50.91.0-0.80.9-0.70.7-0.70.70.70.7-0.50.6-0.50.50.90.9-0.90.8
Pavlov. Cond. lever-magazine prob. diff.1.62.04.1-1.31.5-1.61.4-1.21.2-1.2-1.2-1.20.9-1.20.5-1.1-2.0-2.01.9-1.7
Pavlov. Cond. response bias1.61.95.5-1.11.3-1.51.2-0.90.9-0.9-1.0-0.90.6-0.90.0-0.9-2.3-2.22.3-2.2
Pavlov. Cond. lever latency0.60.83.2-0.60.6-0.80.5-0.20.2-0.2-0.2-0.10.0-0.1-0.4-0.1-1.8-1.61.7-1.7
Pavlov. Cond. magazine entry latency0.30.31.3-0.70.3-0.50.2-0.10.1-0.1-0.1-0.10.1-0.10.10.1-0.9-0.91.1-1.1
Pavlov. Cond. change in total contacts0.30.41.50.4-0.50.6-0.50.2-0.20.20.30.2-0.20.20.20.31.21.1-1.11.1
Pavlov. Cond. index score0.00.00.3-0.0-0.10.1-0.10.1-0.10.10.10.00.00.00.30.10.50.3-0.30.2
Pavlov. Cond. latency score0.00.00.2-0.1-0.10.1-0.0-0.00.0-0.00.0-0.00.1-0.10.4-0.00.50.3-0.20.2
Pavlov. Cond. lever contacts0.81.03.90.9-0.91.0-0.70.4-0.40.40.50.4-0.30.30.20.32.01.8-1.81.8
Pavlov. Cond. magazine entry number0.00.00.10.3-0.00.1-0.0-0.00.0-0.0-0.00.0-0.10.0-0.3-0.10.00.2-0.30.3
Pavlov. Cond. intertrial magazine entries0.10.20.50.2-0.20.1-0.30.4-0.40.40.40.4-0.50.5-0.60.4-0.7-0.50.5-0.6
Pavlov. Cond. lever-magazine prob. diff.0.00.00.3-0.20.1-0.10.1-0.20.2-0.2-0.1-0.20.3-0.20.5-0.10.30.1-0.10.1
Pavlov. Cond. response bias0.30.41.70.5-0.60.6-0.50.3-0.30.30.30.3-0.20.30.30.31.31.1-1.11.1
Time in closed arm before self-admin0.70.81.71.2-0.80.8-0.60.7-0.70.70.50.9-0.60.6-0.60.41.31.1-1.31.3
Time in closed arm after self-admin0.80.81.81.3-0.90.8-0.80.8-0.80.70.70.8-1.00.7-0.80.61.11.0-1.11.0
Time in open arm before self-admin0.20.20.80.9-0.50.5-0.30.6-0.60.60.50.4-0.10.4-0.20.2-0.3-0.10.4-0.4
Time in open arm after self-admin2.83.14.1-1.61.9-1.91.7-1.81.8-1.7-1.6-1.81.9-1.61.8-1.3-2.0-1.91.9-1.8
Bone: periosteal estimation0.81.63.1-1.71.3-1.21.4-1.41.4-1.4-1.4-1.41.6-1.41.7-1.3-0.4-0.60.4-0.2
Bone: periosteal perimeter1.11.84.7-1.10.9-0.71.1-1.51.5-1.5-1.3-1.51.6-1.52.2-1.31.00.7-1.11.3
Bone: post-yield work1.31.82.8-1.71.5-1.61.3-1.21.2-1.2-1.2-1.21.1-1.21.0-1.0-1.5-1.61.6-1.6
Progressive ratio test 1 active lever presses0.50.51.4-0.40.8-0.70.9-0.60.6-0.9-0.9-0.70.9-1.00.4-1.2-0.3-0.60.3-0.2
Progressive ratio test 1 breakpoint0.40.41.2-0.40.7-0.60.8-0.60.6-0.8-0.8-0.60.8-0.90.3-1.1-0.2-0.50.2-0.1
Progressive ratio test 1 inactive lever presses0.70.71.61.3-0.80.7-1.00.8-0.80.70.90.7-1.30.9-1.01.10.60.6-0.50.3
Progressive ratio test 2 active lever presses0.40.41.31.1-0.60.6-0.50.7-0.70.50.50.6-0.70.3-1.00.30.80.4-0.50.4
Progressive ratio test 2 breakpoint0.10.10.50.7-0.20.2-0.10.3-0.30.10.10.2-0.2-0.1-0.6-0.10.60.1-0.30.3
Progressive ratio test 2 inactive lever presses0.10.20.90.8-0.20.2-0.30.3-0.30.30.30.3-0.70.1-0.90.20.30.1-0.20.1
Incentive Sensitization - Responses0.90.91.81.4-1.01.0-0.91.0-1.01.00.91.1-1.00.7-1.20.70.80.6-0.60.4
Incentive Sensitization - Breakpoint0.80.81.81.3-1.01.0-0.91.0-1.01.00.91.0-0.90.7-1.20.70.80.6-0.60.4
Sum of active levers in priming session hrs 5-62.02.02.8-1.41.5-1.61.3-1.31.3-1.4-1.2-1.21.2-1.21.2-1.1-1.7-1.71.6-1.6
Progressive ratio0.30.41.10.2-0.60.7-0.60.6-0.60.70.60.7-0.70.6-1.10.60.30.3-0.30.2
Food seeking constrained by brief footshock0.70.81.61.1-1.00.8-0.81.2-1.21.01.01.3-0.81.0-1.30.6-0.1-0.10.2-0.4
Seeking ratio, punishment vs. effort0.10.20.60.5-0.2-0.0-0.10.3-0.30.20.30.3-0.20.30.00.2-0.6-0.50.7-0.8
Retroperitoneal fat weight3.010.013.7-3.73.6-3.53.4-3.53.5-3.6-3.4-3.43.1-3.43.2-3.0-2.3-2.52.1-1.7
Reaction time number correct0.60.91.60.7-1.00.8-1.11.1-1.11.21.11.1-0.91.2-0.91.20.40.5-0.30.2
Reaction time mean minus median6.58.614.4-2.93.1-3.23.0-2.62.6-2.5-2.7-2.72.5-2.61.9-2.6-3.8-3.73.6-3.3
Reaction time mean minus median AUC6.68.616.8-2.93.1-3.22.8-2.42.4-2.4-2.5-2.62.3-2.31.8-2.3-4.1-3.93.9-3.7
Reaction time num false alarms1.01.43.01.1-1.21.1-1.51.1-1.11.11.41.3-1.51.4-0.71.70.91.0-0.70.5
Reaction time num false alarms AUC0.50.72.00.7-0.90.7-1.10.8-0.80.71.00.9-1.11.1-0.41.40.70.7-0.50.3
Reaction time trials correct on left0.60.91.60.7-1.00.8-1.11.1-1.11.21.11.1-0.91.2-0.91.20.40.5-0.30.2
Reaction time trials on left0.50.81.50.7-0.90.7-1.01.0-1.01.21.01.0-0.91.1-0.81.20.30.5-0.20.1
Reaction time mean2.73.87.7-2.02.0-2.11.8-1.61.6-1.5-1.5-1.51.5-1.41.3-1.4-2.8-2.72.8-2.6
Reaction time mean AUC2.73.67.7-2.01.9-2.11.6-1.51.5-1.5-1.4-1.41.3-1.31.2-1.2-2.8-2.72.8-2.7
Median of all reaction times1.31.84.3-1.41.3-1.41.1-1.01.0-1.0-0.9-0.90.9-0.90.8-0.9-2.1-2.02.1-2.0
Reaction time omissions3.54.78.2-2.52.3-2.42.0-1.91.9-1.9-1.8-1.91.7-1.71.6-1.6-2.9-2.72.7-2.6
Reaction time false alarm rate0.10.20.50.3-0.30.3-0.50.2-0.20.00.30.3-0.50.30.20.60.70.6-0.60.5
Reaction time premature initiation rate0.40.51.60.3-0.20.1-0.10.6-0.60.70.40.5-0.30.4-1.10.2-1.2-0.91.2-1.3
Reaction time premature initiations0.50.71.90.4-0.40.2-0.40.8-0.81.00.70.8-0.60.7-1.30.6-1.2-0.91.2-1.4
Std. dev. reaction times4.86.710.6-2.62.7-2.82.6-2.32.3-2.3-2.3-2.32.3-2.31.9-2.3-3.3-3.23.2-3.0
Reaction time trials completed0.50.81.50.7-0.90.7-1.01.0-1.01.21.01.0-0.91.1-0.81.20.30.5-0.20.1
Reaction time trials AUC0.40.61.20.6-0.90.7-0.90.9-0.91.00.90.9-0.71.0-0.71.10.40.5-0.40.2
Run reversals in cocaine runway, females0.90.94.6-0.50.6-0.41.4-0.60.6-0.6-1.2-0.51.7-1.20.9-2.10.0-0.2-0.10.5
Run reversals in cocaine runway, males0.30.30.90.8-0.40.4-0.20.2-0.20.20.20.4-0.20.2-0.4-0.10.90.8-0.90.9
Latency to leave start box in cocaine runway0.10.10.3-0.50.1-0.10.30.0-0.00.0-0.10.20.4-0.2-0.5-0.4-0.4-0.40.4-0.3
Latency to leave start box in cocaine runway, F0.20.20.6-0.20.0-0.10.20.1-0.10.10.00.20.3-0.1-0.6-0.2-0.7-0.60.8-0.7
Latency to leave start box in cocaine runway, M1.01.02.3-1.50.9-0.91.2-0.80.8-0.8-1.0-0.71.2-1.00.7-1.4-0.9-1.00.8-0.7
Std. dev. time between licks in bursts0.60.71.20.7-0.80.6-0.81.0-1.01.01.01.0-0.90.9-0.91.1-0.1-0.20.6-0.8
Total sessions with >9 infusions0.50.51.1-0.60.8-0.70.9-0.70.7-0.7-0.8-0.71.0-0.80.8-1.0-0.2-0.50.2-0.1
Short access day 1 total inactive lever presses0.10.10.4-0.1-0.20.1-0.50.2-0.20.10.40.2-0.50.3-0.00.6-0.00.20.0-0.1
Short access day 10 total inactive lever presses0.60.71.21.1-0.90.7-1.00.7-0.71.00.90.9-1.00.9-0.61.10.50.6-0.30.2
Short access day 1 total infusions1.71.82.6-1.41.5-1.51.5-1.51.5-1.6-1.5-1.41.5-1.51.5-1.4-0.8-1.00.8-0.6
Short access day 10 total infusions0.10.20.90.8-0.20.3-0.20.4-0.40.20.20.3-0.40.1-1.0-0.10.50.1-0.30.3
Short access total infusions0.10.10.40.6-0.20.2-0.00.3-0.30.20.10.3-0.1-0.0-0.6-0.30.40.0-0.30.3
Short access day 1 locomotion0.40.40.8-0.50.7-0.80.8-0.60.6-0.7-0.8-0.70.9-0.80.8-0.9-0.3-0.50.3-0.3
Short access day 10 total locomotion0.20.20.7-0.20.6-0.60.6-0.40.4-0.4-0.6-0.80.6-0.50.4-0.7-0.1-0.30.1-0.0
Short access total locomotion0.50.50.8-0.50.8-0.80.9-0.70.7-0.6-0.8-0.90.9-0.80.7-0.9-0.2-0.50.2-0.1
One hour access (0.3 mA shock)1.41.74.22.1-1.31.3-1.11.5-1.51.51.11.2-1.31.0-2.00.71.20.8-0.90.8
Compulsive drug intake1.41.42.91.0-1.21.1-1.41.1-1.11.31.31.2-1.71.3-1.51.50.70.9-0.70.4
One hour access (shock baseline)0.91.12.91.7-1.11.1-0.81.2-1.21.10.91.1-0.80.8-1.30.41.10.6-0.80.7
Social response proportion0.30.41.0-1.00.5-0.70.4-0.30.3-0.3-0.3-0.20.1-0.20.3-0.2-0.9-0.91.0-1.0
Social responses1.11.43.3-1.81.3-1.41.2-1.41.4-1.4-1.2-1.11.1-1.21.4-0.9-0.8-1.00.7-0.6
Social time0.20.30.50.1-0.50.5-0.50.7-0.70.60.70.7-0.70.7-0.60.6-0.2-0.20.2-0.4
Soleus weight0.41.21.8-1.21.2-1.11.3-1.21.2-1.2-1.3-1.31.4-1.31.2-1.3-0.5-0.60.4-0.2
Bone: stiffness2.03.24.9-2.02.0-1.91.9-2.12.1-2.1-2.0-2.11.9-2.02.2-1.7-0.7-0.90.6-0.3
Tibialis anterior weight6.121.027.0-5.05.1-5.05.2-5.05.0-4.9-5.2-5.05.1-5.14.4-5.1-3.2-3.42.8-2.0
Time to tail flick, vehicle, before self-admin0.70.73.8-0.2-0.20.30.2-0.00.0-0.1-0.30.00.5-0.30.2-0.81.61.2-1.71.9
Time to tail flick, vehicle, after self-admin3.63.85.52.0-2.02.0-2.11.7-1.71.71.91.8-1.91.9-1.51.92.32.3-2.22.0
Time to tail flick, test, before self-admin0.30.30.6-0.30.5-0.40.5-0.50.5-0.8-0.6-0.50.6-0.60.5-0.50.30.2-0.40.6
Time to tail flick, test, after self-admin3.83.96.92.4-1.91.9-1.81.7-1.71.71.51.7-1.61.6-1.41.42.62.5-2.62.5
Delta time to tail flick, vehicle, before/after SA5.04.98.32.6-2.32.3-2.72.3-2.32.32.62.3-2.72.6-2.32.91.21.4-1.00.5
Delta time to tail flick, test, before/after SA1.21.01.91.4-1.11.1-0.90.9-0.91.20.90.9-0.70.9-0.70.61.31.2-1.21.2
Tibia length0.10.30.8-0.80.4-0.30.5-0.60.6-0.7-0.5-0.50.7-0.60.9-0.50.20.1-0.20.3
Ambulatory time before self-admin3.63.75.6-2.12.2-2.42.1-2.22.2-2.1-2.1-2.11.9-2.02.1-1.7-1.5-1.61.3-1.0
Ambulatory time after self-admin0.80.81.4-0.81.0-1.11.0-1.11.1-1.0-1.2-1.10.9-1.11.2-1.0-0.1-0.2-0.00.2
Bone: tissue strength0.00.00.20.1-0.10.2-0.10.1-0.10.10.10.1-0.10.1-0.10.10.30.3-0.40.4
Total heroin consumption0.30.40.9-0.40.5-0.30.7-0.50.5-0.7-0.7-0.61.0-0.70.8-0.9-0.1-0.20.00.1
Bone: trabecular number1.72.74.41.6-1.71.5-1.81.9-1.91.91.91.9-2.01.9-2.12.10.50.6-0.30.0
Bone: trabecular spacing0.20.20.6-0.60.3-0.20.5-0.40.4-0.4-0.5-0.40.8-0.50.7-0.70.00.0-0.20.3
Bone: trabecular thickness1.31.52.41.3-1.21.0-1.31.5-1.51.51.41.5-1.51.5-1.61.50.00.10.2-0.4
Bone: trabecular tissue density1.92.65.3-1.31.4-1.11.6-1.91.9-1.9-1.8-1.91.9-1.92.3-2.10.60.4-0.81.2
Water consumed over 24 hours0.30.41.1-1.00.7-0.60.6-0.60.6-0.6-0.6-0.60.7-0.50.5-0.5-0.8-0.60.5-0.4
Number of responses in last shaping day2.52.64.2-1.61.7-1.61.9-1.71.7-1.8-1.8-1.62.0-1.91.7-2.0-1.0-1.20.9-0.7