Pigb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Pigb 0.21 0.09 2.5e-09 0.21 0.19 0.22 0.2 2.9e-09 2.0e-08 1.9e-09 1.0e-08
2 pVTA gene expression Pigb 0.32 0.1 0.0e+00 0.27 0.26 0.27 0.28 1.5e-21 5.1e-21 1.9e-21 1.1e-22
3 IL gene expression Pigb 0.35 0.16 2.8e-05 0.23 0.18 0.17 0.19 2.6e-06 4.9e-05 6.5e-05 2.3e-05
4 Brain gene expression Pigb 0.2 0.08 0.0e+00 0.23 0.23 0.23 0.24 2.1e-21 3.3e-21 2.5e-21 4.5e-22
5 Liver mRNA stability Pigb 0.02 0.01 7.3e-03 0.01 0.01 0.01 0.01 1.9e-02 5.7e-02 5.4e-02 3.1e-02
6 PL gene expression Pigb 0.23 0.08 0.0e+00 0.26 0.25 0.26 0.26 8.3e-29 2.3e-27 2.7e-28 9.9e-29
7 PL mRNA stability Pigb 0.02 0.02 4.8e-03 0.03 0.01 0.01 0.01 7.4e-04 1.7e-02 1.5e-02 3.3e-02
8 BLA gene expression Pigb 0.27 0.1 3.2e-14 0.23 0.23 0.23 0.26 3.1e-12 2.0e-12 1.8e-12 5.3e-14
9 NAcc gene expression Pigb 0.11 0.05 0.0e+00 0.13 0.12 0.12 0.13 1.1e-18 2.0e-17 2.0e-18 5.4e-19
10 Adipose mRNA stability Pigb 0.04 0.03 4.7e-03 0 0.01 0.01 0 8.4e-02 3.4e-02 2.7e-02 8.8e-02
11 Liver isoform ratio NM_001108166.3 0.02 0.01 5.2e-03 0 0.01 0 0 1.6e-01 2.1e-02 1.4e-01 1.6e-01
12 Liver isoform ratio XM_063265549.1 0.02 0.02 3.3e-03 0 0.01 0 0 1.7e-01 3.0e-02 3.2e-01 1.6e-01
13 OFC gene expression Pigb 0.22 0.11 6.7e-04 0.11 0.04 0.06 0.07 1.6e-03 3.5e-02 1.4e-02 9.4e-03
14 Adipose isoform ratio XM_063265549.1 0.04 0.02 4.0e-05 0.01 0.03 0.02 0.02 1.4e-02 2.1e-04 2.7e-03 2.2e-03
15 Adipose isoform ratio NM_001108166.3 0.04 0.02 3.2e-05 0.01 0.03 0.02 0.02 1.1e-02 1.6e-04 1.9e-03 1.7e-03
16 Eye isoform ratio NM_001108166.3 0.52 0.25 7.9e-03 0.06 -0 0.02 0.05 4.3e-02 3.6e-01 1.7e-01 5.4e-02
17 Brain isoform ratio XM_063265549.1 0.03 0.02 4.7e-03 0.02 0.02 0.02 0.02 4.7e-03 4.8e-03 7.2e-03 6.5e-03
18 LHb gene expression Pigb 0.17 0.1 4.4e-03 0.09 0.07 0.13 0.08 4.7e-03 7.9e-03 5.0e-04 6.4e-03
19 Eye isoform ratio XM_063265549.1 0.6 0.27 4.5e-03 0.08 0.04 0.08 0.07 2.5e-02 9.6e-02 2.7e-02 2.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.20.31.0-0.3-0.5-0.5-0.5-0.4-0.7-0.5-0.5-0.5-0.30.6-0.6-0.7-0.30.30.2-0.6-1.00.1
Area under the delay curve0.20.21.80.3-0.1-0.20.10.30.20.20.10.1-0.6-0.50.5-0.30.6-0.60.0-0.10.2-1.3
BMI with tail6.923.836.35.84.94.95.15.14.95.15.05.03.5-5.04.84.46.0-6.0-5.55.23.10.6
BMI without tail1.95.911.63.32.22.32.42.42.32.42.32.41.8-1.91.81.93.2-3.3-3.42.91.10.9
Body weight3.615.624.84.84.14.04.24.14.04.34.24.12.6-4.44.43.55.0-5.0-3.83.71.60.1
Weight adjusted by age3.85.710.02.42.63.22.62.32.42.42.62.32.4-2.22.12.82.2-2.2-2.52.41.51.7
Bone surface0.10.21.10.60.40.40.40.40.20.40.40.30.7-0.10.00.30.5-0.5-0.80.60.11.1
Bone volume0.10.30.70.70.50.40.50.50.30.50.50.50.6-0.30.30.40.6-0.6-0.80.4-0.20.5
Breakpoint value in progressive ratio session0.10.10.40.3-0.0-0.10.1-0.00.10.2-0.40.1-0.00.0-0.10.10.5-0.5-0.10.60.5-0.1
Number of licking bursts1.83.04.4-2.1-1.9-1.8-1.9-1.9-1.7-1.8-1.8-1.9-1.41.9-1.9-1.3-2.12.11.4-1.8-0.4-0.3
Context. condit. distance diff. score0.10.10.8-0.10.0-0.2-0.1-0.20.0-0.0-0.0-0.0-0.4-0.30.40.1-0.00.00.3-0.5-0.2-0.9
Locomotion velocity, session 11.21.35.51.01.21.21.21.20.91.21.01.21.5-0.70.60.60.6-0.6-0.90.82.31.5
Locomotion distance, session 10.30.30.7-0.6-0.6-0.6-0.5-0.4-0.6-0.5-0.6-0.5-0.30.8-0.8-0.8-0.60.60.4-0.50.70.2
Locomotion velocity, session 20.10.10.40.1-0.3-0.0-0.2-0.2-0.4-0.2-0.3-0.3-0.00.5-0.6-0.70.3-0.3-0.20.5-0.00.1
Locomotion distance, session 20.10.20.80.3-0.30.0-0.1-0.1-0.3-0.1-0.2-0.20.10.6-0.7-0.30.6-0.6-0.90.90.10.4
Locomotion velocity, session 30.30.41.8-0.2-0.6-0.4-0.5-0.4-0.3-0.5-0.5-0.40.51.2-1.3-0.5-0.50.5-0.10.20.11.1
Locomotion distance, session 33.03.34.9-2.0-2.0-1.9-2.0-2.0-1.9-2.0-2.0-2.0-1.62.2-2.2-2.1-1.71.71.6-1.4-0.8-0.7
Stereotopy head waving bouts, day 31.11.22.10.91.31.11.21.21.41.21.21.21.2-1.31.31.40.5-0.5-0.60.70.91.1
Stereotopy head waving duration, day 32.02.43.41.51.81.71.71.71.81.71.81.71.8-1.71.71.80.9-0.9-0.90.81.21.4
Locomotion velocity, session 70.70.81.2-0.9-1.1-1.0-1.1-1.0-0.9-1.1-1.1-0.9-1.00.9-0.9-0.9-0.80.80.6-0.5-0.8-0.4
Locomotion distance, session 71.51.93.4-1.5-1.6-1.4-1.5-1.5-1.6-1.5-1.5-1.5-1.01.8-1.8-1.6-1.31.30.9-0.8-0.3-0.1
Stereotopy head waving bouts, day 70.70.81.51.00.91.00.90.90.80.90.80.91.1-0.60.50.70.8-0.8-1.00.90.71.2
Stereotopy head waving duration, day 70.81.03.51.00.91.11.00.90.90.90.91.01.5-0.50.40.90.6-0.6-1.11.10.51.9
Locomotion velocity, session 80.30.31.90.60.20.40.30.30.30.30.20.31.20.3-0.40.20.3-0.3-0.80.90.31.4
Locomotion distance, session 80.50.71.6-0.7-1.0-0.9-1.0-1.0-1.0-0.9-1.0-1.0-0.61.2-1.3-1.0-0.40.40.0-0.1-0.6-0.3
Degree of sensitization distance0.00.00.2-0.1-0.1-0.1-0.1-0.1-0.3-0.1-0.1-0.10.10.2-0.2-0.2-0.20.20.1-0.10.30.4
Degree of sensitization stereotypy0.50.51.00.90.70.90.80.70.60.70.70.70.9-0.40.30.50.8-0.8-0.90.70.61.0
Conditioned locomotion0.50.52.70.70.40.30.30.40.50.40.40.4-0.8-1.01.00.51.1-1.2-0.1-0.2-0.7-1.7
Cocaine response after cond. corrected5.06.07.62.42.72.62.72.72.72.72.72.72.6-2.62.62.52.0-2.0-2.02.02.11.6
Cocaine response after cond. not corrected3.84.55.92.12.42.22.42.42.42.42.32.42.1-2.42.42.31.6-1.6-1.71.51.81.2
Cocaine response before conditioning0.91.12.5-0.9-1.1-1.1-1.1-1.1-1.0-1.1-1.1-1.0-1.60.7-0.6-0.8-0.70.60.7-0.8-1.2-1.5
Saline control response0.10.21.10.00.40.30.30.30.20.30.40.30.90.1-0.10.4-0.40.40.1-0.30.71.1
Bone: connectivity density1.62.65.1-1.5-1.7-1.6-1.6-1.6-1.9-1.6-1.6-1.7-0.82.2-2.3-1.7-1.51.51.0-1.3-1.60.8
Bone: cortical apparent density0.81.22.3-1.3-1.0-1.1-1.1-1.1-1.0-1.0-1.1-1.0-1.10.8-0.7-1.0-1.41.41.2-1.50.3-0.6
Bone: cortical area1.01.64.00.71.61.31.41.61.21.51.51.40.8-1.92.01.30.6-0.6-0.0-0.41.2-0.4
Bone: cortical porosity0.70.72.4-0.9-0.8-0.9-0.8-0.7-0.8-0.8-0.8-0.7-0.90.4-0.4-0.8-0.70.71.5-1.0-0.4-1.1
Bone: cortical porosity1.11.22.5-1.0-1.0-1.2-1.1-1.0-1.0-1.1-1.1-1.0-1.30.5-0.4-0.8-0.70.71.5-1.0-1.6-1.5
Bone: cortical thickness0.40.74.4-0.90.1-0.3-0.10.0-0.3-0.0-0.1-0.1-0.7-0.40.6-0.4-0.80.81.6-2.10.9-1.2
Bone: cortical thickness0.10.10.6-0.40.2-0.10.10.10.10.10.10.1-0.1-0.50.60.2-0.50.50.6-0.80.4-0.6
Bone: cortical tissue density0.91.22.1-1.3-1.1-1.1-1.1-1.2-1.1-1.1-1.2-1.1-1.20.9-0.9-1.1-1.41.41.2-1.40.3-0.6
Condit. Reinf. active minus inactive responses1.41.63.7-0.7-1.5-1.4-1.4-1.3-1.2-1.4-1.4-1.3-1.91.0-1.0-1.30.0-0.00.50.1-1.8-1.8
Condit. Reinf. active-inactive response ratio0.60.63.7-0.7-0.5-0.8-0.7-0.5-0.4-0.6-0.6-0.6-1.5-0.30.4-0.5-0.20.20.9-0.2-0.8-1.9
Condit. Reinf. active responses1.01.32.5-0.2-1.5-1.3-1.3-1.2-1.1-1.3-1.4-1.1-1.21.5-1.6-1.30.2-0.2-0.10.5-1.5-0.5
Condit. Reinf. inactive responses0.81.04.40.2-1.1-0.6-0.8-0.8-0.8-0.8-0.9-0.60.31.9-2.1-0.90.0-0.0-0.80.5-0.51.7
Incentive salience index mean1.01.24.1-0.3-1.3-1.2-1.2-1.0-1.0-1.2-1.2-1.0-1.90.6-0.6-1.00.4-0.50.40.3-1.6-2.0
Condit. Reinf. lever presses0.50.83.00.0-1.0-0.9-0.9-0.9-0.7-0.9-1.0-0.7-1.60.4-0.4-0.60.5-0.50.30.4-1.1-1.7
Condit. Reinf. active minus inactive responses1.62.02.81.71.41.51.51.41.41.41.51.41.7-1.11.01.61.5-1.5-1.61.30.51.4
Condit. Reinf. active-inactive response ratio1.82.12.81.51.71.61.71.61.51.61.61.51.5-1.61.61.61.3-1.3-1.10.91.21.0
Condit. Reinf. active responses0.81.02.11.30.91.00.90.91.10.90.91.00.8-0.80.81.31.4-1.4-1.31.0-0.10.5
Condit. Reinf. inactive responses0.60.82.5-0.5-1.1-1.0-1.1-0.9-0.8-1.1-1.1-0.9-1.01.1-1.1-0.7-0.20.20.3-0.5-1.6-0.5
Condit. Reinf. lever presses0.20.21.4-0.5-0.1-0.3-0.3-0.2-0.0-0.3-0.1-0.1-0.5-0.30.40.2-0.60.61.0-1.2-0.1-0.5
Condit. Reinf. lever reinforcers received0.60.81.71.20.80.90.80.80.90.80.80.90.6-0.80.71.11.3-1.3-1.10.6-0.30.2
Conditioned reinforcement - actives0.10.20.90.30.4-0.10.30.20.40.30.40.20.4-0.50.40.90.1-0.1-0.50.9-0.00.6
Conditioned reinforcement - inactives0.20.32.30.30.7-0.10.50.40.70.60.70.40.7-0.50.60.3-0.10.1-0.10.01.50.7
Conditioned locomotion0.20.21.0-0.3-0.2-0.8-0.4-0.5-0.2-0.3-0.2-0.4-0.7-0.20.30.30.1-0.10.30.1-1.0-0.7
Patch foraging indifference point 0 sec0.10.10.30.20.20.40.30.40.40.20.40.30.3-0.10.10.50.2-0.2-0.50.50.30.1
Patch foraging indifference point AUC1.82.64.5-1.4-1.9-1.8-1.8-1.9-1.9-1.7-1.7-1.9-1.62.0-2.1-1.8-0.50.50.5-0.4-2.1-0.9
Delay disc. indifference point, 0s delay1.61.83.0-1.0-1.7-1.7-1.5-1.3-1.4-1.4-1.4-1.4-1.61.5-1.5-1.7-0.50.50.8-0.7-1.2-1.5
Delay disc. indifference point, 16s delay0.30.33.0-0.0-0.1-0.2-0.10.20.0-0.10.00.1-1.0-0.70.8-0.30.3-0.30.6-0.7-0.3-1.7
Delay disc. indifference point, 2s delay0.10.10.1-0.4-0.3-0.4-0.1-0.1-0.30.0-0.1-0.3-0.00.2-0.2-0.4-0.30.30.1-0.30.3-0.2
Delay disc. indifference point, 24s delay0.10.20.9-0.2-0.2-0.4-0.3-0.1-0.1-0.2-0.2-0.1-0.50.0-0.0-0.5-0.10.10.8-1.0-0.1-0.6
Delay disc. indifference point, 4s delay0.50.52.3-0.4-0.7-1.0-0.6-0.5-0.6-0.5-0.6-0.6-1.20.2-0.1-0.90.0-0.00.6-0.6-1.1-1.5
Delay disc. indifference point, 8s delay0.30.41.20.80.30.20.40.60.60.50.40.5-0.2-0.60.60.11.1-1.1-0.60.70.8-0.8
Indifference point function ln k2.34.06.41.92.22.12.22.32.52.22.22.31.9-2.52.52.41.0-1.0-1.21.02.01.1
Indifference point function log k2.34.06.41.92.22.12.22.32.52.22.22.31.9-2.52.52.41.0-1.0-1.21.02.01.1
Patch foraging total patch changes 0 sec0.10.20.60.30.40.60.50.60.50.40.60.50.5-0.30.30.50.3-0.3-0.50.40.80.2
Patch foraging total patch changes 12 sec0.81.02.3-1.1-1.0-1.0-0.9-1.1-1.4-1.0-0.9-1.2-0.51.5-1.5-1.1-0.60.60.7-0.9-1.0-0.0
Patch foraging total patch changes 18 sec0.20.30.7-0.8-0.3-0.5-0.4-0.4-0.6-0.4-0.3-0.5-0.40.5-0.5-0.8-0.30.30.7-0.70.4-0.7
Patch foraging total patch changes 24 sec0.40.82.4-0.8-0.8-0.7-0.7-0.7-1.0-0.8-0.7-0.9-0.21.5-1.5-1.4-0.60.60.4-0.50.60.8
Patch foraging total patch changes 6 sec0.50.72.5-0.5-1.0-0.7-0.8-0.9-1.0-0.9-0.9-1.0-0.61.5-1.6-1.00.1-0.1-0.30.1-0.8-0.1
Patch foraging time to switch 0 sec0.30.71.7-0.9-0.8-0.9-0.9-0.9-0.7-1.0-1.0-0.8-0.80.5-0.4-0.7-0.80.81.0-0.8-1.3-0.6
Patch foraging water rate 0 sec1.22.63.81.61.71.81.81.71.61.81.81.71.5-1.51.51.51.4-1.4-1.41.61.90.9
Patch foraging water rate 12 sec2.65.514.22.32.52.82.72.52.12.72.62.53.0-1.61.51.51.6-1.6-1.71.53.82.7
Patch foraging water rate 18 sec0.50.82.31.00.91.21.11.00.71.11.01.01.0-0.70.70.60.5-0.4-0.20.31.51.1
Patch foraging water rate 24 sec0.20.32.0-0.3-0.2-0.0-0.0-0.1-0.30.1-0.2-0.20.60.7-0.8-0.4-0.70.70.4-0.30.91.4
Patch foraging water rate 6 sec0.60.83.90.60.91.01.01.00.71.01.00.81.1-0.50.50.50.4-0.4-0.40.62.01.4
Seeking ratio, delayed vs. immediate footshock1.31.66.71.20.81.11.01.10.81.01.01.10.8-1.01.01.71.5-1.5-1.92.6-0.00.5
Distance traveled before self-admin0.00.00.4-0.1-0.10.0-0.1-0.2-0.1-0.00.0-0.1-0.0-0.10.10.3-0.10.1-0.20.70.50.1
Distance traveled after self-admin2.32.83.81.41.81.71.81.71.71.81.81.82.0-1.81.81.61.0-0.9-1.51.61.81.6
Extensor digitorum longus weight7.027.437.26.05.45.35.55.55.15.65.55.35.0-4.84.55.16.1-6.1-6.06.11.82.3
Bone: elastic displacement0.00.10.30.30.10.10.10.20.20.20.10.2-0.1-0.20.20.00.4-0.4-0.20.2-0.1-0.5
Bone: elastic work0.10.11.00.30.1-0.0-0.00.10.30.0-0.00.1-0.4-0.50.50.00.3-0.30.1-0.1-0.4-1.0
Bone: endosteal estimation2.45.27.72.52.32.32.32.42.52.32.42.42.0-2.42.32.72.3-2.3-2.52.80.80.9
Bone: endosteal perimeter3.37.09.93.12.82.92.82.92.62.82.82.82.3-2.72.72.73.0-3.0-2.82.50.90.3
Epididymis fat weight0.10.41.5-0.3-0.7-0.6-0.5-0.6-0.7-0.4-0.5-0.70.11.1-1.2-1.1-0.20.2-0.1-0.2-0.90.5
Delta time in closed arm before/after self-admin0.30.21.3-0.4-0.3-0.5-0.4-0.2-0.3-0.3-0.6-0.2-0.6-0.00.1-0.3-0.50.50.7-1.10.1-0.7
Delta time in open arm before/after self-admin0.60.61.6-0.9-0.4-0.6-0.6-0.6-0.7-0.6-0.4-0.60.41.0-1.0-0.6-1.11.10.8-0.8-0.21.3
Diff in mean of infusions in LGA sessions1.01.34.01.50.60.20.60.81.20.80.30.90.0-1.31.21.11.7-1.7-1.42.0-0.3-0.9
Delay discount exponential model param0.10.21.2-0.3-0.00.1-0.2-0.3-0.2-0.2-0.2-0.10.50.4-0.50.3-0.60.60.00.1-0.21.1
Extinction: sum of active levers before priming0.10.10.70.0-0.00.30.1-0.2-0.1-0.1-0.0-0.00.40.3-0.40.0-0.40.40.20.00.70.8
Active lever presses in extinction session 60.70.72.61.00.60.50.80.60.60.80.40.70.9-0.60.50.80.8-0.8-1.21.60.50.7
Bone: final force0.81.32.61.11.41.21.31.31.41.31.21.30.9-1.61.61.11.0-1.0-0.50.71.00.0
Bone: final moment0.71.22.91.01.31.11.11.21.41.21.21.20.7-1.61.71.00.9-0.8-0.20.40.9-0.3
Food consumed during 24 hour testing period1.31.83.20.71.61.51.51.51.51.51.51.41.5-1.61.61.60.4-0.4-0.70.91.81.0
Glucose0.30.51.50.60.50.60.60.60.90.60.60.70.8-0.40.30.80.4-0.4-1.21.00.81.2
Heart weight0.30.42.10.90.40.70.60.5-0.10.70.30.40.3-0.1-0.0-0.11.4-1.5-0.70.7-0.6-0.0
Delay discount hyperbolic model param0.20.21.8-0.10.10.3-0.0-0.2-0.0-0.1-0.10.00.70.4-0.40.3-0.50.5-0.10.1-0.01.3
Intermittent access intake day 1-15 change0.20.41.30.60.5-0.20.40.70.70.50.60.61.0-0.20.20.4-0.10.1-0.80.30.91.2
Intermittent access intake escalation0.30.51.40.70.80.00.60.90.90.80.80.81.2-0.40.40.40.2-0.2-0.90.31.01.1
Intermittent access intake escalation 20.91.01.60.91.10.71.11.31.21.11.01.11.0-1.11.10.80.8-0.8-1.00.81.20.5
Intermitt. access day 1 inactive lever presses0.10.31.4-0.3-0.0-0.9-0.40.10.0-0.2-0.1-0.0-0.4-0.30.40.0-0.80.80.9-1.20.6-0.4
Intermitt. access day 15 inactive lever presses0.40.85.80.81.00.50.91.10.50.90.90.80.9-0.70.8-0.10.4-0.40.4-0.42.40.6
Intermitt. access escalation Index0.20.32.1-0.10.01.00.4-0.0-0.70.00.4-0.1-0.7-0.10.1-0.10.9-0.9-0.20.3-0.5-1.4
Intermittent access day 1 total infusions0.61.02.4-1.6-0.7-1.2-0.9-1.0-1.0-0.7-0.9-1.0-0.50.7-0.6-0.5-1.51.51.3-0.8-0.3-0.0
Intermittent access day 15 total infusions0.20.31.4-0.8-0.4-1.2-0.6-0.5-0.5-0.3-0.4-0.5-0.10.4-0.4-0.2-1.01.00.5-0.4-0.30.3
Intermittent access terminal intake (last 3 days)0.10.10.7-0.4-0.0-0.8-0.3-0.1-0.2-0.1-0.1-0.2-0.1-0.20.30.2-0.60.60.2-0.1-0.2-0.1
Intermittent access total infusions0.30.31.4-0.9-0.1-0.8-0.4-0.4-0.4-0.2-0.2-0.40.10.2-0.2-0.0-1.21.20.7-0.40.30.5
Intermittent access day 1 locomotion1.11.43.3-1.7-1.1-1.6-1.3-1.3-0.9-1.2-1.0-1.3-0.90.9-0.8-0.3-1.81.81.1-0.8-1.20.0
Intermittent access day 15 total locomotion0.10.20.8-0.9-0.0-0.8-0.3-0.4-0.2-0.10.0-0.4-0.3-0.30.40.2-0.90.90.7-0.2-0.1-0.1
Intermittent access total locomotion0.10.10.6-0.30.4-0.10.20.00.40.20.40.00.4-0.40.50.7-0.40.4-0.00.30.20.8
Intermittent access standard deviation0.20.32.00.10.7-0.20.40.70.50.60.50.50.8-0.60.60.4-0.30.3-0.1-0.11.40.7
Left kidney weight2.19.912.93.43.53.53.53.53.53.53.33.63.3-3.23.22.92.6-2.6-2.52.13.32.1
Right kidney weight1.56.78.82.92.73.02.82.92.82.82.62.92.9-2.22.12.12.3-2.3-2.32.12.72.3
Cocaine induced anxiety0.30.53.6-0.3-0.5-0.6-0.5-0.5-0.5-0.5-0.4-0.5-1.3-0.00.1-0.10.3-0.30.10.0-1.1-1.9
Post-drug Anxiety2.52.74.2-1.9-1.9-2.0-1.9-1.7-1.7-1.9-1.8-1.7-1.71.7-1.6-1.2-1.51.50.9-0.9-1.9-1.1
Baseline Anxiety1.72.04.7-1.4-1.6-1.2-1.4-1.3-1.1-1.6-1.3-1.3-0.12.1-2.2-1.2-1.91.90.4-0.7-0.51.6
Tail length0.62.34.1-1.2-1.6-1.5-1.6-1.6-1.4-1.5-1.5-1.4-0.52.0-2.0-1.5-1.81.81.2-1.5-1.70.9
Length with tail0.00.10.50.50.40.40.40.20.40.40.40.30.7-0.20.20.10.1-0.10.0-0.2-0.50.7
Length without tail2.27.211.52.73.13.03.12.82.73.03.02.82.0-3.43.42.53.0-3.0-1.82.11.40.1
Times rat made contact with spout0.30.33.0-0.40.20.20.10.2-0.00.10.10.1-0.3-0.30.3-0.2-0.40.40.8-1.01.7-0.4
Lifetime Intake0.20.31.0-0.9-0.1-0.8-0.4-0.4-0.5-0.2-0.2-0.50.20.3-0.3-0.0-1.01.00.6-0.20.10.6
Liver weight, left2.44.04.92.22.12.22.22.02.22.22.22.12.0-1.71.61.72.1-2.1-2.21.72.01.5
Liver weight, right1.52.64.51.91.61.41.51.51.91.61.51.71.7-1.31.21.71.6-1.6-2.11.80.61.4
Locomotor activity4.97.610.43.22.93.13.03.02.92.93.23.02.5-3.02.92.72.8-2.8-2.62.41.61.2
Locomotor testing distance3.56.28.52.62.72.92.82.72.52.62.92.72.5-2.62.62.32.3-2.2-2.31.92.21.6
Locomotor testing rearing0.71.52.61.21.21.41.41.31.11.31.41.31.6-1.00.91.21.1-1.1-1.61.00.61.3
Locomotion in novel chamber0.10.20.6-0.20.3-0.5-0.10.50.20.00.00.3-0.3-0.70.80.3-0.30.30.2-0.60.2-0.7
Locomotion in novel chamber post-restriction0.20.40.8-0.3-0.7-0.7-0.7-0.6-0.4-0.6-0.9-0.6-0.90.5-0.5-0.8-0.20.20.3-0.8-0.8-0.8
Fecal boli incidents, locomotor time 10.50.72.4-0.7-0.8-0.4-0.6-1.1-1.1-0.7-0.8-1.1-1.30.8-0.7-0.9-0.20.20.5-0.7-1.0-1.5
Change in fecal boli incidents, locomotor task2.42.35.11.11.81.01.41.91.91.41.61.91.7-1.92.01.50.3-0.3-0.91.32.21.4
Time >=10cm from walls, locomotor time 10.70.81.51.11.00.50.60.70.90.60.80.80.1-1.11.11.21.2-1.2-1.21.00.4-0.6
Bouts of movement, locomotor time 10.10.10.90.20.00.20.2-0.0-0.00.20.1-0.1-0.4-0.20.20.30.5-0.5-0.20.20.5-0.9
Total resting periods, locomotor time 10.10.10.80.1-0.00.20.1-0.1-0.10.00.0-0.1-0.4-0.10.10.20.3-0.3-0.1-0.00.6-0.9
Rest time, locomotor task time 10.40.54.8-0.20.0-0.1-0.3-0.40.0-0.5-0.1-0.2-1.4-0.60.70.00.1-0.10.4-0.70.0-2.2
Distance moved, locomotor task time 10.20.41.3-0.3-0.8-0.5-0.5-0.2-0.5-0.4-0.5-0.40.41.0-1.1-0.5-0.40.4-0.10.1-0.71.1
Vertical activity count, locomotor time 10.10.20.8-0.3-0.8-0.3-0.3-0.6-0.6-0.3-0.4-0.6-0.10.7-0.8-0.4-0.10.1-0.20.2-0.90.1
Time >=10cm from walls, locomotor time 20.20.21.50.20.20.10.2-0.10.30.20.40.2-0.5-0.50.60.20.4-0.40.00.21.0-1.2
Bouts of movement, locomotor time 20.20.41.20.60.40.70.50.60.30.40.50.60.4-0.1-0.00.40.9-0.9-1.10.90.80.4
Total resting periods, locomotor time 20.20.41.20.60.50.80.50.60.40.50.50.60.5-0.10.00.40.9-0.9-1.10.91.00.5
Rest time, locomotor task time 20.20.20.8-0.60.0-0.5-0.5-0.3-0.1-0.4-0.4-0.2-0.7-0.20.3-0.0-0.60.60.6-0.7-0.2-0.9
Distance moved, locomotor task time 20.30.31.5-0.1-0.7-0.1-0.3-0.2-0.3-0.4-0.3-0.40.51.1-1.2-0.3-0.20.2-0.50.3-0.61.2
Vertical activity count, locomotor time 20.60.92.2-1.0-1.3-0.4-0.8-1.2-1.1-0.8-0.8-1.1-0.31.4-1.5-0.9-1.11.10.4-0.5-0.40.3
Light reinforcement 11.43.57.52.31.71.81.81.81.81.81.91.70.8-1.91.81.72.7-2.7-2.12.20.7-0.5
Light reinforcement 20.20.31.4-0.30.3-0.3-0.00.20.50.0-0.00.2-0.5-0.81.00.2-0.70.71.2-0.80.1-0.8
Bone: marrow area2.55.57.72.62.42.42.42.52.62.42.52.52.1-2.52.42.82.3-2.3-2.52.80.80.9
Bone: maximum diameter3.56.69.22.53.02.93.03.02.53.03.02.82.2-3.03.02.82.3-2.3-1.91.71.80.4
Bone: maximum force0.81.32.41.21.31.21.21.31.31.31.21.31.0-1.51.61.21.2-1.1-0.80.80.6-0.0
Bone: maximum moment0.71.22.81.01.31.11.21.31.31.21.21.20.8-1.61.71.11.0-1.0-0.50.50.6-0.4
Mean time between licks in bursts0.30.61.3-1.0-0.7-0.9-0.8-0.8-0.8-0.8-0.8-0.8-0.60.6-0.5-0.8-1.11.10.9-1.0-0.2-0.0
Mean num. licks in bursts2.13.35.31.82.22.02.02.11.82.02.02.11.3-2.32.31.31.8-1.8-0.91.11.90.1
Cd content in liver2.22.55.9-1.6-1.6-1.5-1.4-1.5-2.4-1.4-1.7-1.8-1.51.9-2.0-2.4-0.60.51.0-1.1-1.1-1.0
Co content in liver1.51.75.8-1.2-1.2-1.3-1.2-1.1-1.3-1.1-1.2-1.2-2.20.6-0.5-1.4-0.20.21.4-1.4-1.5-2.4
Cu content in liver0.10.10.30.20.10.20.20.10.30.10.20.2-0.2-0.50.60.60.5-0.5-0.20.3-0.6-0.6
Fe content in liver0.20.31.00.50.40.60.50.50.30.50.50.40.80.1-0.10.30.3-0.3-0.50.50.81.0
K content in liver0.60.51.20.90.80.90.90.80.60.90.80.81.1-0.50.40.40.8-0.7-0.50.10.11.0
Mg content in liver0.50.60.80.90.70.90.80.70.70.80.80.80.8-0.70.60.80.9-0.8-0.80.5-0.10.6
Mn content in liver1.01.13.10.81.21.01.21.11.21.21.11.20.5-1.61.80.90.5-0.50.1-0.80.6-0.5
Na content in liver3.23.45.12.31.82.11.91.92.01.91.91.91.9-1.51.41.92.1-2.1-2.22.10.61.0
Rb content in liver0.91.02.71.01.01.01.01.10.81.01.11.01.6-0.50.40.70.8-0.8-1.10.90.71.6
Se content in liver0.20.31.1-0.4-0.10.1-0.0-0.1-0.3-0.1-0.1-0.10.50.6-0.6-0.3-0.80.80.7-1.00.31.1
Sr content in liver1.41.23.8-1.1-1.1-1.0-1.0-1.1-1.2-1.0-1.1-1.2-1.01.3-1.3-1.2-0.80.80.8-1.0-1.9-0.7
Zn content in liver0.10.10.60.2-0.00.1-0.00.0-0.0-0.1-0.00.1-0.4-0.40.40.00.5-0.50.1-0.1-0.7-0.8
Bone: minimum diameter0.50.92.90.71.00.80.91.00.80.90.90.9-0.2-1.61.70.80.9-0.9-0.1-0.1-0.0-1.7
Time in familiar zone, hab. session 10.20.11.30.00.1-0.10.10.0-0.30.1-0.0-0.0-0.6-0.30.3-0.20.5-0.50.2-0.1-0.5-1.1
Time in novel zone, hab. session 10.10.10.6-0.4-0.1-0.1-0.1-0.20.0-0.2-0.0-0.10.40.3-0.3-0.1-0.70.70.3-0.30.40.7
Total zone transitions, hab. session 10.71.03.3-0.9-0.9-0.7-0.8-0.9-1.2-0.8-1.0-0.9-0.41.5-1.6-1.8-0.70.70.7-0.81.00.2
Total locomotion distance, hab. session 10.30.41.6-0.4-0.6-0.4-0.5-0.5-0.7-0.5-0.6-0.6-0.11.2-1.2-1.2-0.40.30.3-0.20.60.6
Locomotion velocity, hab. session 10.10.20.7-0.2-0.3-0.1-0.2-0.2-0.4-0.2-0.3-0.30.10.8-0.8-0.8-0.10.10.10.10.80.6
Time in familiar zone, hab. session 20.20.20.5-0.6-0.4-0.4-0.4-0.4-0.6-0.3-0.4-0.4-0.00.7-0.7-0.4-0.70.70.5-0.60.10.6
Time in novel zone, hab. session 20.50.51.40.60.80.80.70.70.90.70.70.70.3-1.11.20.70.5-0.5-0.50.50.6-0.5
Total zone transitions, hab. session 20.30.41.0-0.0-0.7-0.3-0.5-0.5-0.8-0.5-0.6-0.6-0.70.9-1.0-0.90.5-0.5-0.30.3-0.8-0.3
Total locomotion distance, hab. session 20.20.20.60.3-0.4-0.0-0.2-0.3-0.6-0.3-0.3-0.3-0.50.6-0.7-0.60.8-0.8-0.40.3-0.7-0.4
Locomotion velocity, hab. session 20.20.20.60.2-0.4-0.1-0.2-0.3-0.6-0.3-0.4-0.4-0.60.6-0.6-0.60.7-0.7-0.20.2-0.8-0.5
Novel to familiar place preference ratio1.11.22.21.41.01.01.01.01.31.01.11.00.7-1.21.11.21.5-1.5-1.21.4-0.3-0.3
Novelty place preference1.41.52.61.51.11.11.11.11.31.11.21.10.8-1.31.31.41.6-1.6-1.21.4-0.3-0.3
Time in novel zone, NPP test1.81.92.71.61.41.31.41.41.61.41.41.41.0-1.61.61.71.6-1.6-1.31.50.1-0.0
Total zone transitions, NPP test0.10.21.20.1-0.20.0-0.1-0.1-0.5-0.1-0.3-0.2-0.40.5-0.6-0.90.5-0.5-0.10.11.1-0.4
Total locomotion distance, NPP test0.10.21.00.3-0.10.20.00.0-0.30.0-0.1-0.00.20.6-0.7-0.60.4-0.4-0.40.41.00.5
Locomotion velocity, NPP test0.30.41.8-0.2-0.6-0.3-0.5-0.5-0.9-0.5-0.6-0.6-0.21.2-1.3-1.10.0-0.1-0.00.10.60.4
Intraocular pressure0.10.20.4-0.2-0.3-0.1-0.4-0.2-0.5-0.3-0.5-0.3-0.10.6-0.6-0.5-0.30.30.3-0.5-0.40.4
Delta distance traveled before/after self-admin3.63.85.71.82.21.82.12.32.32.12.02.32.4-2.22.21.91.1-1.1-1.81.41.51.9
Delta ambulatory time before/after self-admin2.53.14.91.52.21.62.02.12.12.01.92.12.2-2.12.11.60.9-0.9-1.20.91.51.8
Parametrial fat weight1.84.25.2-2.2-2.2-2.1-2.1-2.1-2.3-2.1-2.1-2.2-1.92.3-2.2-2.2-2.22.22.0-2.3-0.8-0.7
Pavlov. Cond. lever latency0.60.81.9-0.01.10.91.00.91.01.01.00.81.4-0.91.00.8-0.50.5-0.3-0.40.51.3
Pavlov. Cond. magazine entry latency3.84.913.0-1.3-2.4-2.5-2.3-2.3-2.5-2.3-2.3-2.3-3.41.6-1.5-2.3-0.20.21.8-1.0-3.0-3.6
Pavlov. Cond. change in total contacts1.11.24.7-0.2-1.2-1.3-1.2-1.2-1.0-1.1-1.1-1.0-1.90.6-0.6-0.80.4-0.40.60.2-1.4-2.2
Pavlov. Cond. index score3.34.18.7-1.2-2.4-2.3-2.3-2.3-2.3-2.3-2.3-2.2-2.91.8-1.8-1.9-0.40.31.4-0.5-2.4-2.8
Pavlov. Cond. latency score2.63.36.8-1.0-2.2-2.0-2.0-2.0-2.1-2.0-2.0-1.9-2.61.7-1.7-1.7-0.30.31.2-0.5-2.1-2.4
Pavlov. Cond. lever contacts1.01.23.8-0.3-1.3-1.1-1.2-1.2-1.2-1.2-1.2-1.1-1.80.9-0.9-0.90.3-0.30.50.2-1.1-1.9
Pavlov. Cond. magazine entry number3.84.811.51.42.42.42.32.42.52.32.32.33.3-1.61.62.20.4-0.3-1.70.92.93.4
Pavlov. Cond. intertrial magazine entries0.40.54.60.1-0.20.0-0.1-0.1-0.2-0.1-0.1-0.11.10.9-1.1-0.3-0.40.4-0.70.50.42.1
Pavlov. Cond. lever-magazine prob. diff.3.03.88.2-1.1-2.3-2.1-2.2-2.2-2.2-2.2-2.1-2.1-2.91.7-1.7-1.8-0.20.21.2-0.3-2.5-2.8
Pavlov. Cond. response bias2.63.210.7-0.9-2.0-1.9-1.9-1.9-2.0-1.8-1.9-1.8-2.91.2-1.1-1.70.2-0.21.3-0.3-2.2-3.3
Pavlov. Cond. lever latency0.60.82.60.80.80.70.80.80.80.90.70.81.4-0.50.40.50.3-0.2-0.60.91.61.6
Pavlov. Cond. magazine entry latency4.04.89.8-2.6-2.0-2.0-2.1-2.1-2.3-2.1-2.1-2.2-2.31.9-1.8-2.3-2.32.32.7-3.1-0.9-1.6
Pavlov. Cond. change in total contacts0.91.53.0-1.3-1.1-1.1-1.2-1.2-1.3-1.3-1.2-1.2-1.31.1-1.1-1.2-1.01.01.2-1.7-1.5-0.9
Pavlov. Cond. index score1.62.14.3-1.7-1.4-1.3-1.4-1.5-1.6-1.5-1.4-1.5-1.61.3-1.2-1.3-1.31.21.6-2.1-1.6-1.3
Pavlov. Cond. latency score1.11.53.7-1.4-1.0-1.0-1.1-1.1-1.3-1.2-1.1-1.2-1.40.9-0.9-1.0-1.11.11.4-1.9-1.1-1.2
Pavlov. Cond. lever contacts0.50.72.3-0.8-0.8-0.7-0.8-0.8-0.7-0.9-0.7-0.8-1.30.4-0.4-0.4-0.30.30.6-0.9-1.4-1.5
Pavlov. Cond. magazine entry number3.44.27.32.51.91.92.02.12.22.12.02.12.0-1.91.82.12.2-2.2-2.32.71.21.2
Pavlov. Cond. intertrial magazine entries0.71.02.41.20.90.80.91.10.91.00.81.11.6-0.50.40.90.7-0.7-1.11.41.01.5
Pavlov. Cond. lever-magazine prob. diff.1.92.65.1-1.8-1.5-1.4-1.6-1.6-1.7-1.6-1.5-1.7-1.81.4-1.4-1.5-1.41.41.7-2.3-1.6-1.4
Pavlov. Cond. response bias2.33.15.1-1.8-1.8-1.7-1.8-1.8-1.9-1.8-1.7-1.8-2.31.4-1.4-1.6-1.11.11.6-1.9-2.2-2.1
Time in closed arm before self-admin0.10.21.0-0.2-0.3-0.6-0.4-0.4-0.4-0.3-0.3-0.3-0.70.1-0.1-0.50.2-0.20.30.1-0.4-1.0
Time in closed arm after self-admin0.20.20.4-0.4-0.4-0.7-0.5-0.4-0.5-0.4-0.5-0.4-0.60.3-0.2-0.6-0.30.30.5-0.40.0-0.7
Time in open arm before self-admin1.21.32.11.41.21.31.31.11.21.31.11.10.9-1.41.41.31.0-1.0-0.80.91.20.2
Time in open arm after self-admin0.50.50.90.60.90.70.80.70.70.81.00.70.8-0.80.80.80.4-0.4-0.40.30.90.5
Bone: periosteal estimation2.45.07.32.22.52.42.42.62.52.42.52.51.9-2.72.72.62.0-2.0-1.91.81.40.3
Bone: periosteal perimeter3.05.26.72.42.62.52.52.62.52.52.52.62.1-2.62.62.62.1-2.1-2.11.61.10.3
Bone: post-yield work0.10.10.40.50.20.20.20.30.20.20.20.30.4-0.10.10.40.5-0.5-0.70.6-0.20.3
Progressive ratio test 1 active lever presses0.20.30.7-0.8-0.4-0.8-0.5-0.5-0.5-0.5-0.3-0.5-0.00.5-0.5-0.1-0.80.80.40.0-0.10.4
Progressive ratio test 1 breakpoint0.20.30.8-0.8-0.4-0.9-0.6-0.6-0.5-0.5-0.4-0.6-0.10.6-0.6-0.1-0.90.90.5-0.0-0.10.3
Progressive ratio test 1 inactive lever presses1.31.96.4-1.9-1.0-1.8-1.3-1.2-1.2-1.3-1.0-1.3-0.21.3-1.2-0.5-2.52.51.2-1.00.20.9
Progressive ratio test 2 active lever presses0.50.61.10.30.90.60.80.70.30.90.90.51.0-0.70.60.80.5-0.5-0.61.01.00.8
Progressive ratio test 2 breakpoint0.50.51.20.20.90.60.80.70.20.90.90.41.0-0.60.60.60.5-0.5-0.60.91.10.9
Progressive ratio test 2 inactive lever presses0.20.32.7-0.40.6-0.20.30.3-0.20.40.5-0.00.4-0.40.50.1-0.60.60.9-0.41.60.4
Incentive Sensitization - Responses1.31.82.91.11.61.31.61.30.71.71.51.11.0-1.51.51.11.6-1.6-1.11.51.70.1
Incentive Sensitization - Breakpoint1.21.52.51.01.41.31.51.20.61.61.31.00.9-1.31.30.91.5-1.6-1.01.41.60.1
Sum of active levers in priming session hrs 5-60.10.10.40.20.30.40.40.20.30.30.20.30.5-0.20.20.40.0-0.0-0.30.60.00.6
Progressive ratio0.81.27.2-0.5-1.1-1.1-1.1-0.9-1.2-1.1-1.2-1.0-1.70.4-0.4-0.40.2-0.20.00.1-2.7-1.9
Food seeking constrained by brief footshock0.20.31.20.30.20.40.50.50.50.40.40.40.80.2-0.20.20.1-0.1-0.90.80.41.1
Seeking ratio, punishment vs. effort2.73.88.81.72.02.32.21.92.02.02.22.02.9-1.00.91.41.1-1.0-1.71.52.73.0
Retroperitoneal fat weight0.52.36.3-1.3-1.3-1.1-1.1-1.3-1.5-1.1-1.3-1.4-0.71.9-1.9-2.5-1.61.61.6-2.01.70.1
Reaction time number correct0.91.63.01.51.21.41.31.31.41.31.31.31.6-0.80.71.31.2-1.2-1.71.10.31.6
Reaction time mean minus median0.20.61.1-1.0-0.8-0.8-0.7-1.0-0.8-0.7-0.6-0.8-0.60.9-0.9-0.4-1.01.00.4-0.6-0.3-0.1
Reaction time mean minus median AUC0.51.22.3-1.3-1.1-1.2-1.1-1.3-1.2-1.0-1.0-1.1-0.61.3-1.3-0.8-1.51.50.9-1.10.10.2
Reaction time num false alarms0.30.40.9-0.5-0.7-0.5-0.7-0.6-0.4-0.8-0.6-0.5-0.20.9-0.9-0.5-0.90.90.5-0.50.20.6
Reaction time num false alarms AUC0.20.31.4-0.1-0.30.0-0.3-0.2-0.1-0.4-0.3-0.10.40.7-0.7-0.3-0.70.70.3-0.31.01.2
Reaction time trials correct on left0.91.63.01.51.21.41.31.31.41.31.31.31.6-0.80.71.31.2-1.2-1.71.10.31.6
Reaction time trials on left0.91.62.91.51.11.41.31.21.41.31.31.31.6-0.80.71.21.1-1.1-1.71.10.31.7
Reaction time mean2.03.24.8-2.2-1.8-2.1-1.9-1.9-1.9-1.7-1.8-1.8-1.71.6-1.5-1.4-2.22.22.0-1.8-1.1-1.1
Reaction time mean AUC2.03.14.6-2.2-1.8-2.1-1.9-1.9-1.9-1.7-1.9-1.8-1.71.6-1.5-1.4-2.12.11.8-1.5-1.3-1.1
Median of all reaction times3.04.35.9-2.4-2.0-2.4-2.2-2.2-2.1-2.0-2.2-2.1-2.11.7-1.5-1.7-2.42.42.4-2.0-1.5-1.5
Reaction time omissions0.20.20.7-0.5-0.3-0.2-0.2-0.4-0.6-0.1-0.3-0.40.40.8-0.8-0.6-0.60.60.2-0.30.50.7
Reaction time false alarm rate0.71.01.9-1.0-1.0-0.9-1.1-0.9-0.8-1.2-1.0-0.9-0.61.1-1.1-1.0-1.41.41.3-1.00.70.1
Reaction time premature initiation rate0.50.72.11.00.70.60.70.80.70.70.80.81.3-0.40.31.00.6-0.6-1.10.80.21.4
Reaction time premature initiations1.11.93.71.61.31.21.31.31.31.41.41.41.9-0.90.71.61.2-1.2-1.81.30.11.9
Std. dev. reaction times1.22.23.5-1.8-1.5-1.6-1.5-1.7-1.6-1.5-1.4-1.6-1.21.6-1.6-1.3-1.91.91.4-1.5-0.7-0.6
Reaction time trials completed0.91.62.91.51.11.41.31.21.41.31.31.31.6-0.80.71.21.1-1.1-1.71.10.31.7
Reaction time trials AUC0.71.32.41.41.01.31.21.11.21.21.21.21.5-0.70.61.11.1-1.1-1.61.00.31.6
Run reversals in cocaine runway, females0.10.10.40.10.20.40.10.60.6-0.00.30.40.3-0.20.20.1-0.40.40.2-0.40.50.6
Run reversals in cocaine runway, males0.30.31.10.3-0.30.1-0.0-0.2-0.3-0.0-0.1-0.10.50.8-1.0-0.40.3-0.3-0.60.7-0.51.1
Latency to leave start box in cocaine runway1.31.53.91.31.11.51.21.11.11.11.31.01.0-1.01.01.61.3-1.3-2.01.60.00.6
Latency to leave start box in cocaine runway, F0.40.41.70.60.30.60.50.40.40.40.50.30.90.0-0.10.90.3-0.3-1.30.90.11.2
Latency to leave start box in cocaine runway, M4.44.16.22.02.12.52.22.01.92.02.22.01.1-2.32.32.12.4-2.4-2.32.20.5-0.4
Std. dev. time between licks in bursts0.00.10.20.3-0.2-0.1-0.1-0.10.0-0.1-0.1-0.1-0.00.2-0.2-0.20.4-0.4-0.40.0-0.50.2
Total sessions with >9 infusions0.50.62.4-0.9-0.4-0.9-0.6-0.6-0.5-0.5-0.3-0.50.60.8-0.80.2-1.31.30.30.0-0.31.6
Short access day 1 total inactive lever presses0.40.51.9-0.10.80.30.50.60.40.50.70.51.1-0.60.60.5-0.80.80.4-0.91.31.4
Short access day 10 total inactive lever presses0.20.51.5-0.9-0.2-0.3-0.2-0.3-0.9-0.4-0.1-0.5-0.00.4-0.3-0.8-1.11.11.2-1.21.10.3
Short access day 1 total infusions0.10.20.9-0.40.2-0.10.0-0.1-0.10.10.3-0.10.6-0.10.10.8-0.50.5-0.40.6-0.71.0
Short access day 10 total infusions1.21.53.1-1.8-1.1-1.5-1.3-1.3-1.5-1.1-1.1-1.3-0.81.1-1.0-0.7-1.71.71.2-0.8-1.1-0.1
Short access total infusions0.70.92.5-1.3-0.7-1.3-1.0-0.9-1.0-0.8-0.8-0.9-0.01.0-1.0-0.3-1.61.60.8-0.4-0.70.8
Short access day 1 locomotion0.00.00.20.10.10.00.0-0.10.10.00.3-0.00.1-0.20.20.50.1-0.1-0.10.4-0.40.2
Short access day 10 total locomotion0.10.21.0-0.50.1-0.1-0.0-0.00.5-0.10.30.00.4-0.30.30.8-1.01.0-0.1-0.20.00.9
Short access total locomotion0.20.31.3-0.8-0.3-0.6-0.4-0.6-0.2-0.50.0-0.5-0.10.2-0.20.4-1.11.10.6-0.5-0.30.4
One hour access (0.3 mA shock)0.91.12.20.61.41.11.31.20.71.41.01.00.9-1.41.50.90.9-0.9-0.50.61.40.0
Compulsive drug intake1.21.54.60.91.51.31.41.51.11.41.01.41.5-1.21.30.80.6-0.6-0.60.22.11.1
One hour access (shock baseline)0.10.20.5-0.6-0.2-0.3-0.2-0.4-0.7-0.2-0.1-0.5-0.60.1-0.1-0.3-0.20.20.6-0.3-0.3-0.7
Social response proportion0.91.02.50.90.90.70.81.11.20.80.80.90.2-1.51.61.41.1-1.1-0.70.8-0.1-0.6
Social responses0.10.10.20.40.30.30.30.50.20.20.30.40.2-0.30.30.30.5-0.5-0.30.20.50.0
Social time0.30.40.80.40.60.70.60.70.60.50.60.70.8-0.60.60.90.1-0.1-0.20.50.90.8
Soleus weight14.041.154.97.36.46.66.76.76.86.66.66.65.9-6.05.76.57.1-7.1-7.37.43.03.4
Bone: stiffness1.01.74.11.11.31.31.41.41.31.41.41.32.0-0.80.81.30.7-0.7-1.31.21.21.8
Tibialis anterior weight13.545.855.17.37.27.17.27.37.17.27.27.27.1-6.46.17.06.6-6.6-7.07.44.14.4
Time to tail flick, vehicle, before self-admin1.61.73.2-0.8-1.7-1.4-1.6-1.4-1.2-1.6-1.6-1.4-1.51.7-1.8-1.0-0.40.40.6-0.1-1.8-0.9
Time to tail flick, vehicle, after self-admin0.20.20.9-0.00.40.30.30.40.50.20.40.40.1-0.80.90.9-0.20.2-0.20.5-0.50.0
Time to tail flick, test, before self-admin1.81.95.4-0.9-1.5-1.2-1.4-1.3-1.4-1.5-1.4-1.4-2.20.9-0.8-1.3-0.40.30.8-0.7-2.3-2.3
Time to tail flick, test, after self-admin2.02.02.6-1.5-1.6-1.6-1.5-1.4-1.4-1.5-1.3-1.4-1.41.5-1.4-1.5-1.61.61.3-1.3-1.4-0.8
Delta time to tail flick, vehicle, before/after SA0.50.41.5-0.00.80.60.60.60.70.60.80.70.5-1.11.20.9-0.30.4-0.40.30.10.4
Delta time to tail flick, test, before/after SA0.50.52.40.20.80.50.60.60.70.70.90.70.8-0.70.80.7-0.40.40.2-0.21.60.7
Tibia length0.31.04.00.40.90.50.70.90.80.80.90.8-0.4-1.82.01.20.7-0.70.10.0-0.6-1.6
Ambulatory time before self-admin0.20.30.5-0.7-0.7-0.5-0.6-0.7-0.7-0.7-0.5-0.7-0.50.6-0.6-0.4-0.70.70.5-0.10.4-0.1
Ambulatory time after self-admin2.02.44.01.11.71.51.61.61.61.61.61.71.9-1.81.81.50.6-0.5-1.21.42.01.7
Bone: tissue strength0.50.51.3-0.8-0.7-0.9-0.8-0.7-0.3-0.7-0.7-0.7-0.70.4-0.3-0.6-0.90.91.1-0.80.0-0.3
Total heroin consumption0.60.72.01.00.50.90.80.40.50.80.20.61.1-0.0-0.10.71.1-1.1-1.11.40.71.2
Bone: trabecular number1.11.73.3-1.2-1.4-1.4-1.4-1.3-1.7-1.3-1.5-1.4-0.91.6-1.7-1.5-1.00.90.9-1.1-1.80.0
Bone: trabecular spacing0.10.11.5-0.00.00.10.00.00.20.00.0-0.0-0.3-0.00.0-0.20.1-0.10.1-0.30.5-1.2
Bone: trabecular thickness0.30.30.60.30.70.60.70.70.50.70.70.60.6-0.70.80.60.00.00.1-0.70.40.7
Bone: trabecular tissue density8.011.815.93.34.03.83.93.93.73.93.83.83.7-3.83.83.52.7-2.6-2.42.23.32.1
Water consumed over 24 hours0.10.20.7-0.6-0.1-0.3-0.3-0.2-0.2-0.2-0.3-0.2-0.7-0.10.2-0.2-0.50.50.8-0.80.1-0.8
Number of responses in last shaping day0.10.20.60.60.40.10.30.20.50.20.50.40.4-0.40.40.80.1-0.1-0.30.20.30.2