Hub : Genes

Ubap1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Ubap1 0.04 0.03 6.9e-04 0.02 0.02 0.03 0.02 1.1e-03 9.9e-04 8.2e-04 1.4e-03
2 NAcc gene expression Ubap1 0.03 0.03 2.6e-03 0.02 0.02 0.01 0.02 3.5e-03 2.2e-03 1.4e-02 2.4e-03
3 Adipose gene expression Ubap1 0.21 0.1 0.0e+00 0.19 0.19 0.19 0.19 1.1e-20 2.7e-20 1.4e-20 8.7e-21
4 Adipose mRNA stability Ubap1 0.07 0.05 6.0e-05 0.03 0.03 0.03 0.03 4.9e-04 2.8e-04 3.5e-04 9.6e-05
5 Liver gene expression Ubap1 0.13 0.07 1.9e-13 0.11 0.12 0.12 0.11 1.7e-12 3.8e-13 1.0e-12 1.7e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5
Bone: apparent density1.32.22.4-1.41.5-1.51.5-1.4
Area under the delay curve1.01.11.30.8-1.11.1-1.11.1
BMI with tail2.16.87.2-2.52.7-2.62.7-2.6
BMI without tail3.87.911.0-3.32.9-2.62.8-2.3
Body weight2.610.813.2-3.63.4-3.13.4-2.8
Weight adjusted by age0.30.30.9-0.0-0.50.5-0.41.0
Bone surface0.40.81.3-1.10.9-0.90.8-0.6
Bone volume0.61.01.3-1.11.0-1.11.0-0.8
Breakpoint value in progressive ratio session1.51.62.50.8-1.31.4-1.21.6
Number of licking bursts6.77.98.4-2.82.8-2.82.9-2.6
Context. condit. distance diff. score0.00.00.10.3-0.20.0-0.20.1
Locomotion velocity, session 11.01.13.0-0.6-0.81.1-0.71.7
Locomotion distance, session 10.30.40.9-0.5-0.40.6-0.40.9
Locomotion velocity, session 22.02.32.6-1.61.6-1.51.3-1.5
Locomotion distance, session 21.01.43.6-1.91.1-0.91.0-0.6
Locomotion velocity, session 30.20.20.6-0.2-0.30.4-0.30.8
Locomotion distance, session 31.01.12.3-1.51.0-1.01.0-0.5
Stereotopy head waving bouts, day 30.10.10.30.1-0.20.0-0.00.6
Stereotopy head waving duration, day 30.10.10.20.4-0.30.10.00.4
Locomotion velocity, session 70.00.00.00.2-0.20.0-0.20.2
Locomotion distance, session 70.10.10.3-0.50.3-0.30.3-0.1
Stereotopy head waving bouts, day 72.83.13.6-1.81.8-1.81.9-1.5
Stereotopy head waving duration, day 70.91.11.4-1.11.1-1.11.2-0.9
Locomotion velocity, session 80.20.20.6-0.3-0.30.3-0.40.8
Locomotion distance, session 80.10.10.3-0.6-0.00.1-0.10.4
Degree of sensitization distance0.50.50.90.9-0.70.6-0.70.5
Degree of sensitization stereotypy1.51.71.8-1.31.3-1.31.3-1.2
Conditioned locomotion0.20.30.70.0-0.50.5-0.40.8
Cocaine response after cond. corrected2.62.94.31.3-1.81.7-1.52.1
Cocaine response after cond. not corrected2.42.64.31.0-1.71.7-1.42.1
Cocaine response before conditioning1.11.31.6-1.21.2-1.21.0-1.1
Saline control response0.71.01.9-1.40.9-0.91.1-0.3
Bone: connectivity density0.60.91.0-0.81.0-1.01.0-1.0
Bone: cortical apparent density0.20.30.70.10.5-0.70.2-0.9
Bone: cortical area2.63.94.2-1.92.0-2.01.9-2.0
Bone: cortical porosity0.30.40.70.8-0.60.7-0.50.4
Bone: cortical porosity0.00.00.00.10.00.10.1-0.1
Bone: cortical thickness1.42.23.1-1.11.6-1.61.4-1.8
Bone: cortical thickness0.00.00.10.40.0-0.1-0.1-0.3
Bone: cortical tissue density0.10.20.50.20.3-0.50.1-0.7
Condit. Reinf. active minus inactive responses0.50.50.7-0.70.8-0.80.6-0.7
Condit. Reinf. active-inactive response ratio0.40.50.80.9-0.60.5-0.80.4
Condit. Reinf. active responses2.83.43.9-1.91.9-2.01.7-1.6
Condit. Reinf. inactive responses3.54.24.5-2.12.1-2.12.0-1.9
Incentive salience index mean3.54.35.8-2.42.2-2.12.0-1.7
Condit. Reinf. lever presses7.610.115.6-4.03.3-3.03.1-2.3
Condit. Reinf. active minus inactive responses0.60.70.9-0.90.9-0.80.8-0.8
Condit. Reinf. active-inactive response ratio0.00.00.1-0.20.2-0.10.1-0.3
Condit. Reinf. active responses2.02.83.5-1.91.8-1.61.5-1.6
Condit. Reinf. inactive responses4.04.95.8-2.12.4-2.12.1-2.3
Condit. Reinf. lever presses3.14.34.9-1.72.2-2.21.9-2.2
Condit. Reinf. lever reinforcers received2.43.34.1-2.01.9-1.81.7-1.7
Conditioned reinforcement - actives1.21.31.4-1.11.2-1.11.1-1.2
Conditioned reinforcement - inactives0.60.70.9-0.70.8-0.90.9-0.7
Conditioned locomotion0.60.70.9-1.00.8-0.70.8-0.8
Patch foraging indifference point 0 sec0.40.62.0-0.5-0.50.7-0.41.4
Patch foraging indifference point AUC4.75.48.0-2.82.4-2.02.2-2.0
Delay disc. indifference point, 0s delay1.51.71.91.2-1.31.3-1.41.3
Delay disc. indifference point, 16s delay2.02.03.00.9-1.51.5-1.31.7
Delay disc. indifference point, 2s delay0.30.30.5-0.20.5-0.60.5-0.7
Delay disc. indifference point, 24s delay0.40.40.50.6-0.60.7-0.70.6
Delay disc. indifference point, 4s delay0.10.10.20.4-0.40.4-0.40.2
Delay disc. indifference point, 8s delay0.00.00.10.1-0.20.2-0.20.2
Indifference point function ln k1.72.43.01.7-1.61.3-1.61.5
Indifference point function log k1.72.43.01.7-1.61.3-1.61.5
Patch foraging total patch changes 0 sec0.20.30.9-0.9-0.10.20.10.9
Patch foraging total patch changes 12 sec1.21.52.3-1.51.3-1.01.3-1.0
Patch foraging total patch changes 18 sec0.10.20.6-0.80.4-0.10.1-0.1
Patch foraging total patch changes 24 sec1.01.22.4-1.51.1-0.81.1-0.6
Patch foraging total patch changes 6 sec0.81.13.3-1.81.0-0.70.9-0.2
Patch foraging time to switch 0 sec1.01.63.31.8-1.31.1-1.20.6
Patch foraging water rate 0 sec0.40.61.9-1.40.7-0.40.7-0.1
Patch foraging water rate 12 sec0.00.00.1-0.1-0.0-0.10.00.3
Patch foraging water rate 18 sec0.60.91.2-0.60.9-0.91.0-1.1
Patch foraging water rate 24 sec0.10.20.30.20.3-0.50.3-0.6
Patch foraging water rate 6 sec1.21.71.9-1.41.4-1.31.4-1.1
Seeking ratio, delayed vs. immediate footshock3.23.64.4-2.12.0-1.91.8-1.8
Distance traveled before self-admin4.64.98.2-2.92.3-2.02.2-1.6
Distance traveled after self-admin3.23.64.0-1.71.9-2.02.0-1.9
Extensor digitorum longus weight5.019.721.9-4.74.5-4.54.6-3.8
Bone: elastic displacement4.24.87.22.7-2.22.0-2.31.6
Bone: elastic work0.70.93.01.7-0.70.5-0.9-0.2
Bone: endosteal estimation0.61.22.8-1.71.1-1.00.9-0.5
Bone: endosteal perimeter0.51.12.7-1.60.9-1.00.9-0.4
Epididymis fat weight0.30.81.5-1.20.9-0.71.0-0.5
Delta time in closed arm before/after self-admin1.81.82.1-1.01.4-1.41.3-1.4
Delta time in open arm before/after self-admin0.30.30.40.3-0.60.6-0.50.6
Diff in mean of infusions in LGA sessions0.00.00.10.2-0.20.1-0.10.0
Delay discount exponential model param0.91.01.1-0.71.0-1.11.0-1.1
Extinction: sum of active levers before priming1.01.01.21.1-1.10.9-0.90.9
Active lever presses in extinction session 62.12.02.41.3-1.51.5-1.51.3
Bone: final force1.52.42.7-1.61.5-1.51.6-1.4
Bone: final moment1.32.12.2-1.41.4-1.51.5-1.4
Food consumed during 24 hour testing period0.60.71.4-1.20.8-0.70.9-0.4
Glucose0.50.71.4-1.20.9-0.60.7-0.6
Heart weight0.30.50.8-0.90.7-0.50.8-0.5
Delay discount hyperbolic model param0.80.81.0-0.71.0-1.00.9-1.0
Intermittent access intake day 1-15 change1.41.41.9-0.91.2-1.21.2-1.4
Intermittent access intake escalation1.21.21.3-1.01.1-1.11.1-1.1
Intermittent access intake escalation 22.82.73.3-1.31.7-1.81.6-1.8
Intermitt. access day 1 inactive lever presses0.30.30.7-0.80.6-0.40.5-0.3
Intermitt. access day 15 inactive lever presses0.00.00.1-0.40.1-0.10.20.1
Intermitt. access escalation Index0.50.40.9-1.00.6-0.60.7-0.4
Intermittent access day 1 total infusions0.70.91.10.7-0.91.0-0.91.0
Intermittent access day 15 total infusions0.40.40.6-0.80.6-0.50.6-0.6
Intermittent access terminal intake (last 3 days)1.31.51.9-1.41.2-1.21.3-1.0
Intermittent access total infusions0.60.71.2-1.10.8-0.60.8-0.6
Intermittent access day 1 locomotion2.22.32.71.3-1.61.6-1.61.4
Intermittent access day 15 total locomotion1.11.11.31.0-1.11.1-1.20.9
Intermittent access total locomotion0.30.30.60.8-0.60.5-0.60.2
Intermittent access standard deviation0.70.70.9-0.90.9-0.80.8-0.8
Left kidney weight0.20.61.3-1.20.7-0.61.0-0.2
Right kidney weight0.00.10.1-0.2-0.00.10.30.3
Cocaine induced anxiety0.40.50.50.7-0.70.7-0.70.7
Post-drug Anxiety0.40.50.8-0.90.7-0.70.6-0.5
Baseline Anxiety0.91.01.2-0.81.0-1.01.0-1.1
Tail length1.64.87.4-2.72.3-2.02.1-1.7
Length with tail0.41.42.9-1.71.2-1.01.1-0.6
Length without tail0.40.81.00.9-1.00.8-0.91.0
Times rat made contact with spout1.01.21.4-0.91.1-1.21.1-1.1
Lifetime Intake0.60.71.7-1.30.8-0.60.7-0.4
Liver weight, left0.50.81.0-1.00.9-0.81.0-0.7
Liver weight, right0.00.10.1-0.0-0.20.1-0.30.3
Locomotor activity0.00.00.1-0.10.2-0.10.2-0.2
Locomotor testing distance0.10.10.2-0.0-0.20.4-0.30.5
Locomotor testing rearing0.91.42.2-1.51.3-1.11.0-0.9
Locomotion in novel chamber0.00.00.10.2-0.10.0-0.1-0.0
Locomotion in novel chamber post-restriction2.83.44.2-1.41.9-2.01.8-2.1
Fecal boli incidents, locomotor time 11.41.61.91.4-1.31.2-1.21.1
Change in fecal boli incidents, locomotor task0.50.51.4-1.20.6-0.40.7-0.3
Time >=10cm from walls, locomotor time 10.00.00.1-0.1-0.10.20.00.3
Bouts of movement, locomotor time 10.70.71.71.3-0.90.7-0.60.6
Total resting periods, locomotor time 10.80.92.41.6-0.90.7-0.70.6
Rest time, locomotor task time 10.40.41.81.3-0.3-0.2-0.1-0.4
Distance moved, locomotor task time 10.80.92.6-1.60.9-0.60.8-0.2
Vertical activity count, locomotor time 10.40.41.5-1.20.5-0.10.40.1
Time >=10cm from walls, locomotor time 20.00.00.1-0.20.00.10.10.1
Bouts of movement, locomotor time 21.01.01.2-1.01.1-1.01.1-1.0
Total resting periods, locomotor time 20.60.60.7-0.70.8-0.80.8-0.8
Rest time, locomotor task time 20.20.21.01.0-0.40.0-0.10.1
Distance moved, locomotor task time 20.30.40.5-0.70.7-0.50.3-0.7
Vertical activity count, locomotor time 20.10.10.5-0.70.3-0.0-0.1-0.1
Light reinforcement 10.50.92.6-1.60.5-0.21.10.3
Light reinforcement 20.40.51.4-0.8-0.40.60.11.2
Bone: marrow area0.71.43.0-1.71.2-1.21.0-0.7
Bone: maximum diameter2.24.04.9-2.22.0-2.01.9-1.7
Bone: maximum force3.56.06.5-2.52.5-2.52.6-2.2
Bone: maximum moment2.95.05.3-2.22.3-2.32.3-2.1
Mean time between licks in bursts0.30.40.50.6-0.70.4-0.70.6
Mean num. licks in bursts2.53.03.61.9-1.81.6-1.81.5
Cd content in liver1.71.82.5-1.21.3-1.41.2-1.6
Co content in liver1.31.51.81.1-1.31.2-1.21.4
Cu content in liver0.20.30.90.9-0.50.2-0.50.2
Fe content in liver0.20.30.9-0.5-0.30.3-0.31.0
K content in liver0.80.81.00.7-0.91.0-0.81.0
Mg content in liver1.21.31.51.2-1.21.1-1.11.0
Mn content in liver0.80.91.2-0.30.9-1.11.1-1.1
Na content in liver0.70.81.21.1-0.90.8-0.80.6
Rb content in liver4.45.55.82.4-2.42.4-2.32.2
Se content in liver2.83.44.1-1.52.0-1.81.9-2.0
Sr content in liver0.70.60.8-0.60.8-0.90.9-0.8
Zn content in liver0.20.20.40.00.3-0.70.4-0.6
Bone: minimum diameter0.00.00.10.2-0.1-0.0-0.2-0.0
Time in familiar zone, hab. session 10.60.51.50.60.5-0.70.3-1.2
Time in novel zone, hab. session 13.43.36.01.0-1.91.7-1.82.4
Total zone transitions, hab. session 10.00.10.10.1-0.20.3-0.40.2
Total locomotion distance, hab. session 10.60.81.6-0.50.9-0.80.8-1.3
Locomotion velocity, hab. session 11.62.23.1-1.31.6-1.31.5-1.8
Time in familiar zone, hab. session 20.20.20.60.8-0.1-0.0-0.3-0.5
Time in novel zone, hab. session 22.12.13.71.0-1.51.4-1.31.9
Total zone transitions, hab. session 20.10.10.6-0.80.10.10.10.3
Total locomotion distance, hab. session 20.50.61.0-1.00.8-0.60.8-0.7
Locomotion velocity, hab. session 20.60.81.3-1.10.9-0.70.9-0.8
Novel to familiar place preference ratio4.54.65.41.8-2.22.2-2.12.3
Novelty place preference5.65.76.22.2-2.52.5-2.42.5
Time in novel zone, NPP test6.66.87.32.4-2.72.6-2.62.7
Total zone transitions, NPP test0.10.20.9-0.90.2-0.00.30.2
Total locomotion distance, NPP test0.60.92.2-1.50.9-0.51.0-0.5
Locomotion velocity, NPP test1.01.43.0-1.71.2-0.71.2-0.8
Intraocular pressure1.42.03.2-1.81.4-1.31.4-1.0
Delta distance traveled before/after self-admin0.00.00.10.4-0.1-0.0-0.0-0.1
Delta ambulatory time before/after self-admin0.30.30.70.8-0.60.4-0.40.3
Parametrial fat weight0.00.00.2-0.40.10.10.10.2
Pavlov. Cond. lever latency7.08.911.63.4-3.13.0-3.02.3
Pavlov. Cond. magazine entry latency0.30.40.7-0.80.7-0.80.4-0.5
Pavlov. Cond. change in total contacts2.02.23.4-1.81.6-1.51.4-1.0
Pavlov. Cond. index score3.14.04.8-2.22.1-2.11.9-1.7
Pavlov. Cond. latency score2.93.74.5-2.12.0-2.11.8-1.6
Pavlov. Cond. lever contacts5.05.87.5-2.72.5-2.52.3-1.9
Pavlov. Cond. magazine entry number0.60.81.11.0-0.91.1-0.70.7
Pavlov. Cond. intertrial magazine entries0.30.30.4-0.50.6-0.60.6-0.6
Pavlov. Cond. lever-magazine prob. diff.3.13.84.5-2.02.0-2.11.8-1.7
Pavlov. Cond. response bias2.73.34.4-2.11.9-1.91.6-1.4
Pavlov. Cond. lever latency4.25.77.82.0-2.52.8-2.12.5
Pavlov. Cond. magazine entry latency0.10.10.20.4-0.1-0.2-0.4-0.1
Pavlov. Cond. change in total contacts1.72.43.8-0.91.6-1.91.1-1.9
Pavlov. Cond. index score0.81.02.0-0.51.0-1.40.5-1.2
Pavlov. Cond. latency score1.21.52.6-0.71.2-1.60.8-1.5
Pavlov. Cond. lever contacts2.12.84.1-1.41.8-2.01.4-1.8
Pavlov. Cond. magazine entry number0.60.81.40.2-0.81.2-0.41.2
Pavlov. Cond. intertrial magazine entries0.10.20.4-0.60.40.10.6-0.2
Pavlov. Cond. lever-magazine prob. diff.0.81.02.0-0.51.0-1.40.5-1.3
Pavlov. Cond. response bias1.21.62.6-0.91.3-1.60.9-1.5
Time in closed arm before self-admin3.23.74.11.9-2.02.0-2.01.6
Time in closed arm after self-admin0.30.30.50.7-0.50.6-0.60.3
Time in open arm before self-admin1.51.62.9-1.71.3-1.21.3-0.7
Time in open arm after self-admin0.91.01.9-1.40.9-0.91.0-0.5
Bone: periosteal estimation1.32.74.0-2.01.7-1.71.5-1.3
Bone: periosteal perimeter0.20.41.1-1.00.5-0.60.5-0.1
Bone: post-yield work1.11.62.7-1.71.2-1.21.3-0.7
Progressive ratio test 1 active lever presses0.40.40.8-0.90.6-0.60.6-0.3
Progressive ratio test 1 breakpoint0.50.51.1-1.00.7-0.70.7-0.4
Progressive ratio test 1 inactive lever presses0.30.31.1-1.10.4-0.30.50.1
Progressive ratio test 2 active lever presses0.10.10.4-0.60.10.00.10.2
Progressive ratio test 2 breakpoint0.10.10.1-0.3-0.10.2-0.20.3
Progressive ratio test 2 inactive lever presses0.50.61.1-1.10.8-0.70.7-0.5
Incentive Sensitization - Responses0.20.20.5-0.70.4-0.30.4-0.2
Incentive Sensitization - Breakpoint0.10.10.3-0.50.2-0.10.2-0.1
Sum of active levers in priming session hrs 5-65.55.35.82.0-2.42.4-2.32.4
Progressive ratio0.40.50.70.3-0.60.8-0.80.7
Food seeking constrained by brief footshock5.46.612.3-3.52.6-2.32.5-1.7
Seeking ratio, punishment vs. effort3.13.84.4-2.11.9-2.02.1-1.6
Retroperitoneal fat weight0.00.20.50.7-0.40.3-0.20.2
Reaction time number correct0.10.10.1-0.2-0.20.4-0.30.4
Reaction time mean minus median1.62.24.1-0.41.4-1.61.5-2.0
Reaction time mean minus median AUC2.43.24.7-0.91.7-1.91.9-2.2
Reaction time num false alarms0.40.50.9-0.00.7-0.80.6-1.0
Reaction time num false alarms AUC0.71.01.2-0.61.1-1.11.1-1.1
Reaction time trials correct on left0.10.10.1-0.2-0.20.4-0.30.4
Reaction time trials on left0.10.10.2-0.1-0.30.4-0.30.5
Reaction time mean0.30.41.51.2-0.50.1-0.5-0.3
Reaction time mean AUC0.30.51.71.3-0.50.0-0.6-0.3
Median of all reaction times1.21.73.21.8-1.30.9-1.40.7
Reaction time omissions0.71.01.91.4-1.10.6-0.90.8
Reaction time false alarm rate0.30.40.60.10.6-0.70.6-0.8
Reaction time premature initiation rate1.62.14.02.0-1.41.2-1.40.9
Reaction time premature initiations1.41.92.81.7-1.41.3-1.51.0
Std. dev. reaction times0.50.71.80.30.6-0.90.6-1.3
Reaction time trials completed0.10.10.2-0.1-0.30.4-0.30.5
Reaction time trials AUC0.10.10.2-0.1-0.30.5-0.30.5
Run reversals in cocaine runway, females0.00.00.10.3-0.10.10.2-0.3
Run reversals in cocaine runway, males0.00.00.00.10.1-0.10.1-0.1
Latency to leave start box in cocaine runway1.01.11.2-1.01.1-1.11.0-1.0
Latency to leave start box in cocaine runway, F0.10.10.20.2-0.30.4-0.30.4
Latency to leave start box in cocaine runway, M2.01.92.4-1.61.4-1.41.4-1.1
Std. dev. time between licks in bursts0.20.30.50.7-0.50.5-0.40.3
Total sessions with >9 infusions0.10.10.3-0.6-0.10.2-0.10.4
Short access day 1 total inactive lever presses2.02.24.6-2.11.5-1.21.4-0.9
Short access day 10 total inactive lever presses0.30.40.6-0.80.7-0.60.6-0.4
Short access day 1 total infusions1.51.63.8-1.91.2-1.01.2-0.5
Short access day 10 total infusions0.10.20.7-0.80.10.1-0.00.3
Short access total infusions0.30.31.3-1.10.4-0.20.30.1
Short access day 1 locomotion0.70.81.10.4-0.91.0-1.00.9
Short access day 10 total locomotion0.50.61.11.0-0.70.7-0.80.3
Short access total locomotion0.10.10.2-0.1-0.30.4-0.40.3
One hour access (0.3 mA shock)0.10.20.6-0.80.4-0.30.3-0.0
Compulsive drug intake0.00.00.1-0.3-0.00.2-0.30.2
One hour access (shock baseline)0.10.10.4-0.70.2-0.10.30.2
Social response proportion2.42.63.31.6-1.61.8-1.61.3
Social responses0.30.40.7-0.80.6-0.50.7-0.5
Social time0.20.20.40.1-0.50.4-0.40.6
Soleus weight0.51.43.10.1-1.21.1-1.01.8
Bone: stiffness4.57.17.7-2.82.7-2.62.8-2.4
Tibialis anterior weight6.622.430.8-5.64.7-4.74.7-3.8
Time to tail flick, vehicle, before self-admin2.12.22.71.6-1.51.5-1.51.2
Time to tail flick, vehicle, after self-admin0.00.00.0-0.0-0.00.1-0.20.0
Time to tail flick, test, before self-admin0.70.60.7-0.70.8-0.80.8-0.8
Time to tail flick, test, after self-admin0.20.20.5-0.30.5-0.30.2-0.7
Delta time to tail flick, vehicle, before/after SA0.50.40.7-0.90.7-0.60.5-0.6
Delta time to tail flick, test, before/after SA0.40.40.60.6-0.60.7-0.70.5
Tibia length0.10.20.6-0.2-0.30.5-0.20.8
Ambulatory time before self-admin2.62.75.6-2.41.6-1.41.6-1.0
Ambulatory time after self-admin0.70.81.1-1.00.9-0.90.9-0.7
Bone: tissue strength0.30.30.3-0.50.5-0.50.5-0.5
Total heroin consumption0.40.50.60.6-0.70.7-0.70.8
Bone: trabecular number1.42.12.3-1.31.5-1.51.5-1.5
Bone: trabecular spacing0.10.10.3-0.10.4-0.30.3-0.6
Bone: trabecular thickness0.10.10.10.4-0.30.1-0.40.2
Bone: trabecular tissue density3.44.85.3-2.32.3-2.22.2-2.1
Water consumed over 24 hours1.31.51.8-1.31.2-1.31.4-1.0
Number of responses in last shaping day0.40.41.0-0.7-0.30.6-0.41.0