Fam81a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative TSS XM_006243379.4 0.04 0.04 1.3e-05 0.04 0.04 0.04 0.04 6.1e-05 6.0e-05 9.8e-05 8.7e-05
2 PL isoform ratio XM_006243378.4 0.04 0.04 2.0e-05 0.03 0.03 0.03 0.03 1.3e-04 1.2e-04 1.4e-04 1.9e-04
3 IL gene expression Fam81a 0.25 0.18 7.5e-05 0.12 0.14 0.13 0.14 6.7e-04 3.9e-04 4.1e-04 3.2e-04
4 PL isoform ratio XM_006243379.4 0.04 0.04 3.7e-05 0.03 0.03 0.03 0.03 2.2e-04 2.4e-04 2.1e-04 3.6e-04
5 Brain gene expression Fam81a 0.17 0.12 4.1e-15 0.15 0.14 0.15 0.15 3.7e-14 3.7e-13 1.2e-13 1.0e-13
6 OFC mRNA stability Fam81a 0.24 0.18 4.9e-04 0.1 0.11 0.11 0.11 3.0e-03 1.6e-03 1.7e-03 1.3e-03
7 PL mRNA stability Fam81a 0.03 0.05 5.7e-03 0.01 0.01 0.01 0.01 1.0e-02 4.7e-02 3.0e-02 1.6e-02
8 LHb gene expression Fam81a 0.18 0.15 2.8e-03 0.07 0.1 0.08 0.1 1.1e-02 2.4e-03 6.9e-03 2.3e-03
9 PL gene expression Fam81a 0.09 0.07 2.7e-10 0.09 0.09 0.09 0.09 7.3e-10 9.4e-10 1.3e-09 1.0e-09
10 PL alternative TSS XM_006243378.4 0.04 0.04 6.0e-05 0.03 0.02 0.03 0.02 5.1e-04 9.5e-04 9.0e-04 1.2e-03
11 RMTg alternative TSS NM_001108163.1 0.73 0.16 2.6e-03 0.08 0.08 0.05 0.06 3.3e-03 4.0e-03 1.8e-02 1.2e-02
12 PL alternative TSS XM_006243378.4 0.04 0.04 4.4e-05 0.03 0.03 0.03 0.03 2.1e-04 3.1e-04 5.7e-04 3.3e-04
13 PL alternative TSS XM_006243379.4 0.05 0.04 2.8e-05 0.03 0.03 0.03 0.03 1.6e-04 1.9e-04 2.7e-04 2.5e-04
14 PL intron excision ratio chr8_70803970_70820689 0.03 0.02 1.5e-03 0.02 0.02 0.02 0.02 1.8e-03 1.9e-03 2.4e-03 2.5e-03
15 PL intron excision ratio chr8_70803970_70821437 0.03 0.02 1.7e-03 0.02 0.02 0.02 0.02 1.8e-03 2.2e-03 2.7e-03 2.6e-03
16 NAcc gene expression Fam81a 0.03 0.03 1.9e-03 0.02 0.02 0.03 0.02 3.3e-03 2.0e-03 4.2e-04 4.0e-03
17 pVTA gene expression Fam81a 0.27 0.22 1.5e-06 0.16 0.15 0.13 0.16 3.2e-07 6.3e-07 2.8e-06 2.9e-07
18 Brain mRNA stability Fam81a 0.13 0.16 4.3e-04 0.04 0.03 0.03 0.04 7.2e-05 8.8e-04 4.7e-04 1.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.61.01.11.0-1.01.0-1.0-1.01.0-0.91.1-0.91.00.81.1-1.11.1-1.1-0.70.9-1.0
Area under the delay curve0.10.10.3-0.30.3-0.30.20.3-0.30.4-0.30.2-0.30.2-0.30.3-0.30.30.60.2-0.0
BMI with tail6.019.521.0-4.64.5-4.54.34.4-4.64.5-4.44.6-4.6-3.9-4.54.5-4.54.54.4-4.14.2
BMI without tail2.96.07.5-2.52.5-2.52.52.4-2.62.5-2.52.6-2.2-2.3-2.42.4-2.42.42.7-2.32.4
Body weight4.719.621.0-4.54.5-4.44.34.4-4.54.5-4.34.4-4.5-4.4-4.44.4-4.44.44.6-4.44.3
Weight adjusted by age5.96.78.1-2.62.6-2.52.72.6-2.62.7-2.42.8-2.7-2.6-2.52.5-2.52.52.3-2.52.6
Bone surface0.00.10.1-0.30.3-0.20.20.2-0.30.3-0.10.3-0.2-0.3-0.20.2-0.20.20.3-0.30.2
Bone volume0.00.00.10.0-0.00.1-0.1-0.10.0-0.00.1-0.00.1-0.10.1-0.10.1-0.10.10.0-0.2
Breakpoint value in progressive ratio session0.40.40.7-0.60.6-0.70.80.6-0.70.6-0.70.6-0.6-0.7-0.70.7-0.70.7-0.2-0.70.8
Number of licking bursts2.42.84.91.8-1.81.7-1.6-1.61.8-1.81.6-1.91.61.51.5-1.51.5-1.5-2.21.6-1.3
Context. condit. distance diff. score1.01.21.41.1-1.11.2-1.2-1.01.1-1.11.1-1.11.11.11.1-1.11.1-1.1-1.11.1-1.1
Locomotion velocity, session 10.70.82.2-0.70.7-0.91.10.6-0.70.5-1.10.5-0.7-1.5-0.70.7-0.70.70.3-1.51.3
Locomotion distance, session 10.50.60.80.8-0.80.8-0.8-0.90.8-0.90.8-0.90.90.40.9-0.90.9-0.9-0.80.4-0.1
Locomotion velocity, session 20.00.10.3-0.20.2-0.20.20.2-0.10.1-0.20.1-0.2-0.6-0.10.1-0.10.10.0-0.50.2
Locomotion distance, session 20.00.00.3-0.00.1-0.10.2-0.0-0.10.0-0.20.10.0-0.4-0.10.1-0.10.10.2-0.40.5
Locomotion velocity, session 30.10.10.30.4-0.40.3-0.2-0.40.4-0.40.2-0.40.4-0.10.5-0.50.5-0.50.2-0.1-0.5
Locomotion distance, session 32.42.63.21.7-1.71.6-1.6-1.71.7-1.81.5-1.81.71.31.7-1.71.7-1.7-1.51.2-1.2
Stereotopy head waving bouts, day 30.81.01.8-1.11.1-1.00.91.2-1.11.1-1.01.1-1.2-0.7-0.90.9-0.90.91.4-0.70.3
Stereotopy head waving duration, day 31.01.11.6-1.21.1-1.11.01.3-1.11.2-1.11.1-1.2-0.7-1.11.1-1.11.11.0-0.70.7
Locomotion velocity, session 72.22.43.31.7-1.61.4-1.2-1.81.6-1.71.2-1.61.81.31.7-1.71.7-1.7-1.71.2-0.8
Locomotion distance, session 71.82.23.31.6-1.61.4-1.2-1.71.6-1.71.2-1.71.71.41.4-1.41.4-1.4-1.81.3-1.1
Stereotopy head waving bouts, day 72.02.24.8-1.61.6-1.41.41.6-1.61.7-1.31.6-1.6-0.9-1.41.4-1.41.41.3-1.02.2
Stereotopy head waving duration, day 71.82.25.0-1.61.6-1.41.41.6-1.61.7-1.31.7-1.7-0.9-1.31.3-1.31.31.2-0.92.2
Locomotion velocity, session 80.20.21.30.00.0-0.20.60.00.0-0.2-0.4-0.2-0.0-0.9-0.20.2-0.20.2-0.5-0.81.1
Locomotion distance, session 80.91.31.61.2-1.21.2-1.1-1.21.2-1.31.2-1.21.30.81.2-1.21.2-1.2-1.10.9-0.6
Degree of sensitization distance0.10.10.30.2-0.20.2-0.1-0.30.1-0.20.2-0.10.30.60.1-0.10.1-0.1-0.40.5-0.4
Degree of sensitization stereotypy1.21.34.4-1.21.2-1.11.11.1-1.21.2-1.01.3-1.2-0.8-1.01.0-1.01.00.9-0.82.1
Conditioned locomotion0.10.10.70.3-0.30.3-0.2-0.20.3-0.40.2-0.40.20.40.3-0.30.3-0.3-0.50.3-0.9
Cocaine response after cond. corrected3.23.64.6-1.91.9-2.02.01.9-1.91.8-2.11.8-1.9-1.9-2.02.0-2.02.01.4-1.81.6
Cocaine response after cond. not corrected1.71.92.4-1.31.3-1.41.41.4-1.31.3-1.51.3-1.3-1.4-1.51.5-1.51.51.1-1.31.1
Cocaine response before conditioning1.11.31.91.2-1.21.3-1.3-1.21.2-1.01.4-1.01.31.11.1-1.11.1-1.1-0.71.2-0.9
Saline control response0.00.10.20.0-0.10.2-0.4-0.00.10.10.30.00.10.50.1-0.10.1-0.1-0.10.50.0
Bone: connectivity density1.21.82.21.3-1.31.4-1.5-1.41.3-1.31.5-1.31.41.21.4-1.41.4-1.4-1.11.3-1.3
Bone: cortical apparent density0.50.60.70.8-0.80.8-0.8-0.80.8-0.80.8-0.80.70.80.8-0.80.8-0.8-0.80.8-0.7
Bone: cortical area0.00.00.10.2-0.20.2-0.2-0.10.3-0.20.2-0.30.1-0.00.1-0.10.1-0.1-0.3-0.00.0
Bone: cortical porosity0.50.60.80.7-0.70.8-0.8-0.80.7-0.60.9-0.60.80.90.8-0.80.8-0.8-0.40.7-0.5
Bone: cortical porosity1.41.51.91.3-1.31.3-1.3-1.31.3-1.21.3-1.21.41.31.2-1.21.2-1.2-1.01.2-1.0
Bone: cortical thickness1.42.22.71.5-1.51.6-1.5-1.41.6-1.61.5-1.61.41.31.5-1.51.5-1.5-1.71.3-1.3
Bone: cortical thickness1.11.32.41.2-1.21.2-1.1-1.11.3-1.31.1-1.31.10.91.1-1.11.1-1.1-1.50.8-0.7
Bone: cortical tissue density0.50.60.70.8-0.80.8-0.8-0.80.8-0.80.8-0.80.70.80.8-0.80.8-0.8-0.80.7-0.7
Condit. Reinf. active minus inactive responses0.10.10.40.1-0.10.3-0.2-0.30.1-0.00.4-0.00.2-0.10.2-0.20.2-0.20.6-0.1-0.5
Condit. Reinf. active-inactive response ratio0.60.60.90.8-0.80.9-0.9-0.80.8-0.81.0-0.70.80.70.8-0.80.8-0.8-0.60.8-0.9
Condit. Reinf. active responses0.40.52.1-0.70.7-0.50.60.5-0.70.7-0.40.7-0.5-0.8-0.60.6-0.60.61.5-0.90.3
Condit. Reinf. inactive responses1.31.52.5-1.21.2-1.21.21.0-1.21.2-1.11.2-1.1-1.3-1.21.2-1.21.21.6-1.41.4
Incentive salience index mean0.10.10.60.1-0.10.3-0.3-0.30.2-0.10.4-0.10.2-0.20.3-0.30.3-0.30.7-0.2-0.5
Condit. Reinf. lever presses0.10.20.30.4-0.40.5-0.5-0.50.5-0.40.5-0.40.4-0.00.6-0.60.6-0.60.3-0.0-0.4
Condit. Reinf. active minus inactive responses2.53.14.5-1.81.8-1.71.61.8-1.81.8-1.61.8-1.8-2.0-1.61.6-1.61.62.1-1.91.9
Condit. Reinf. active-inactive response ratio1.01.11.5-1.11.1-1.01.01.1-1.01.1-0.91.1-1.2-1.0-1.01.0-1.01.01.2-0.91.1
Condit. Reinf. active responses1.11.53.0-1.21.2-1.11.01.1-1.21.3-1.01.2-1.1-1.6-1.01.0-1.01.01.7-1.51.4
Condit. Reinf. inactive responses0.10.20.30.4-0.40.4-0.5-0.60.3-0.20.4-0.30.6-0.20.5-0.50.5-0.50.2-0.1-0.2
Condit. Reinf. lever presses0.81.01.51.0-1.01.1-1.2-1.00.9-1.01.2-0.81.10.81.2-1.21.2-1.2-0.50.8-0.8
Condit. Reinf. lever reinforcers received0.60.81.8-0.90.9-0.80.70.8-0.91.0-0.70.9-0.8-1.2-0.60.6-0.60.61.3-1.11.1
Conditioned reinforcement - actives0.30.30.5-0.60.6-0.70.60.7-0.60.7-0.70.5-0.70.3-0.70.7-0.70.7-0.20.20.3
Conditioned reinforcement - inactives0.00.00.4-0.00.0-0.10.20.20.00.0-0.2-0.1-0.10.1-0.20.2-0.20.2-0.7-0.10.1
Conditioned locomotion0.30.30.80.5-0.50.4-0.6-0.50.4-0.60.4-0.50.50.80.4-0.40.4-0.4-0.70.9-0.6
Patch foraging indifference point 0 sec0.10.21.2-0.40.4-0.30.20.4-0.40.4-0.30.4-0.4-0.8-0.20.2-0.20.21.1-0.80.3
Patch foraging indifference point AUC0.10.10.60.2-0.10.00.0-0.10.1-0.4-0.0-0.20.3-0.40.0-0.00.0-0.0-0.8-0.50.3
Delay disc. indifference point, 0s delay0.10.10.40.3-0.30.3-0.4-0.20.3-0.30.3-0.40.20.70.3-0.30.3-0.3-0.40.5-0.5
Delay disc. indifference point, 16s delay0.10.10.5-0.00.0-0.1-0.10.1-0.00.1-0.2-0.1-0.10.7-0.20.2-0.20.2-0.50.6-0.2
Delay disc. indifference point, 2s delay0.00.00.2-0.10.1-0.00.10.2-0.10.20.00.1-0.20.40.0-0.00.0-0.0-0.00.4-0.1
Delay disc. indifference point, 24s delay0.20.20.40.3-0.30.3-0.6-0.30.3-0.20.3-0.40.30.50.3-0.30.3-0.30.50.6-0.6
Delay disc. indifference point, 4s delay0.00.00.2-0.10.1-0.1-0.10.1-0.10.3-0.00.10.10.5-0.00.0-0.00.00.20.5-0.3
Delay disc. indifference point, 8s delay0.20.21.2-0.40.4-0.40.40.4-0.40.5-0.40.4-0.3-0.1-0.40.4-0.40.41.1-0.10.2
Indifference point function ln k0.40.61.5-0.80.8-0.80.70.8-0.80.8-0.70.8-0.9-0.4-0.70.7-0.70.71.2-0.40.3
Indifference point function log k0.40.61.5-0.80.8-0.80.70.8-0.80.8-0.70.8-0.9-0.4-0.70.7-0.70.71.2-0.40.3
Patch foraging total patch changes 0 sec0.20.31.4-0.50.5-0.40.30.4-0.50.5-0.40.5-0.5-0.9-0.30.3-0.30.31.2-0.90.3
Patch foraging total patch changes 12 sec0.00.10.10.2-0.20.2-0.4-0.20.1-0.10.3-0.10.3-0.20.3-0.30.3-0.30.1-0.2-0.3
Patch foraging total patch changes 18 sec0.10.20.4-0.40.4-0.40.30.4-0.40.2-0.40.4-0.3-0.5-0.40.4-0.40.40.1-0.60.6
Patch foraging total patch changes 24 sec0.10.10.40.1-0.10.0-0.1-0.2-0.1-0.10.10.10.2-0.70.2-0.20.2-0.20.2-0.50.6
Patch foraging total patch changes 6 sec0.30.41.0-0.60.6-0.60.50.4-0.70.5-0.60.7-0.4-1.0-0.50.5-0.50.51.0-1.00.7
Patch foraging time to switch 0 sec0.91.42.61.2-1.21.1-1.2-1.21.2-1.11.1-1.21.21.61.1-1.11.1-1.1-0.81.5-1.2
Patch foraging water rate 0 sec2.03.24.2-1.81.8-1.81.71.9-1.81.8-1.71.8-1.8-2.1-1.71.7-1.71.71.8-2.01.8
Patch foraging water rate 12 sec3.04.67.2-2.22.2-2.12.22.2-2.12.0-2.02.2-2.1-2.7-2.02.0-2.02.02.0-2.61.8
Patch foraging water rate 18 sec0.40.52.8-0.60.6-0.50.40.4-0.70.7-0.30.9-0.6-1.0-0.50.5-0.50.51.7-0.70.1
Patch foraging water rate 24 sec0.20.30.8-0.50.5-0.40.60.4-0.40.5-0.40.4-0.5-0.9-0.40.4-0.40.40.9-0.80.6
Patch foraging water rate 6 sec1.11.62.5-1.31.3-1.21.11.3-1.31.3-1.01.3-1.3-1.5-1.21.2-1.21.21.6-1.31.3
Seeking ratio, delayed vs. immediate footshock0.80.91.3-0.90.9-0.91.10.9-0.80.9-1.01.0-0.7-0.9-1.01.0-1.01.00.6-0.91.1
Distance traveled before self-admin0.40.50.8-0.60.6-0.70.60.9-0.60.7-0.70.5-0.60.4-0.90.9-0.90.9-0.80.40.3
Distance traveled after self-admin1.61.72.2-1.41.3-1.41.31.5-1.51.4-1.41.3-1.4-1.0-1.41.4-1.41.40.5-1.11.2
Extensor digitorum longus weight8.031.433.3-5.65.7-5.75.85.7-5.55.5-5.75.4-5.6-5.5-5.75.7-5.75.74.6-5.75.7
Bone: elastic displacement0.30.40.6-0.70.7-0.60.60.7-0.70.7-0.60.7-0.7-0.6-0.60.6-0.60.60.3-0.60.4
Bone: elastic work0.00.00.0-0.00.0-0.10.10.1-0.0-0.0-0.1-0.0-0.1-0.2-0.00.0-0.00.0-0.2-0.2-0.1
Bone: endosteal estimation2.14.55.0-2.12.1-2.12.12.2-2.12.1-2.12.1-2.2-2.1-2.22.2-2.22.21.8-2.12.1
Bone: endosteal perimeter3.26.67.4-2.62.6-2.62.62.7-2.52.5-2.62.4-2.6-2.7-2.72.7-2.72.72.2-2.62.3
Epididymis fat weight0.00.10.8-0.20.2-0.10.00.3-0.20.2-0.00.3-0.2-0.3-0.10.1-0.10.10.9-0.30.1
Delta time in closed arm before/after self-admin0.20.22.60.3-0.30.30.2-0.30.3-0.30.3-0.40.30.40.2-0.20.2-0.2-1.60.2-0.2
Delta time in open arm before/after self-admin1.00.91.11.0-1.01.0-1.0-1.01.0-1.10.9-1.01.00.61.0-1.01.0-1.0-1.00.7-0.9
Diff in mean of infusions in LGA sessions1.31.42.0-1.31.3-1.21.21.2-1.31.4-1.11.4-1.3-0.9-1.21.2-1.21.20.7-0.91.0
Delay discount exponential model param0.20.20.50.5-0.40.4-0.3-0.50.5-0.60.4-0.40.4-0.10.5-0.50.5-0.5-0.7-0.1-0.1
Extinction: sum of active levers before priming0.00.00.10.1-0.10.1-0.3-0.20.0-0.10.1-0.20.10.20.1-0.10.1-0.1-0.30.4-0.2
Active lever presses in extinction session 60.10.10.4-0.10.1-0.20.10.1-0.10.2-0.20.1-0.10.4-0.20.2-0.20.20.70.5-0.1
Bone: final force0.30.51.0-0.70.7-0.70.80.7-0.60.6-0.80.5-0.7-0.9-0.70.7-0.70.70.6-1.00.8
Bone: final moment0.10.10.4-0.30.3-0.30.40.3-0.20.2-0.40.2-0.3-0.5-0.30.3-0.30.30.3-0.60.4
Food consumed during 24 hour testing period1.01.22.3-1.21.2-1.00.91.3-1.21.3-0.91.2-1.3-0.8-1.11.1-1.11.10.7-0.81.5
Glucose0.30.51.2-0.60.6-0.60.60.6-0.60.6-0.70.5-0.6-1.1-0.60.6-0.60.60.5-1.00.8
Heart weight0.40.60.8-0.70.7-0.80.80.8-0.70.7-0.80.7-0.8-0.6-0.90.9-0.90.9-0.0-0.70.8
Delay discount hyperbolic model param0.10.10.30.3-0.30.3-0.2-0.30.3-0.40.3-0.30.2-0.30.3-0.30.3-0.3-0.6-0.2-0.0
Intermittent access intake day 1-15 change1.01.02.00.9-0.91.0-0.9-0.80.9-0.91.0-0.90.91.20.9-0.90.9-0.9-1.41.3-1.0
Intermittent access intake escalation1.31.22.11.0-1.01.1-1.1-0.91.0-1.01.1-1.01.01.41.0-1.01.0-1.0-1.41.5-1.2
Intermittent access intake escalation 20.00.00.2-0.10.1-0.10.10.3-0.10.1-0.10.0-0.10.4-0.20.2-0.20.2-0.50.5-0.0
Intermitt. access day 1 inactive lever presses1.71.82.51.4-1.41.4-1.6-1.41.4-1.41.3-1.51.31.31.3-1.31.3-1.3-0.21.3-1.5
Intermitt. access day 15 inactive lever presses0.10.10.50.1-0.10.1-0.20.10.2-0.10.0-0.30.10.7-0.00.0-0.00.0-0.30.6-0.3
Intermitt. access escalation Index1.41.21.4-1.11.1-1.20.91.0-1.21.1-1.21.2-1.1-1.0-1.21.2-1.21.20.5-1.11.1
Intermittent access day 1 total infusions0.20.30.60.5-0.50.5-0.2-0.50.5-0.50.4-0.70.60.80.4-0.40.4-0.4-0.70.7-0.4
Intermittent access day 15 total infusions1.11.32.81.0-1.01.0-0.8-0.91.0-1.01.0-1.01.01.61.0-1.01.0-1.0-1.71.6-1.1
Intermittent access terminal intake (last 3 days)0.40.41.60.5-0.50.5-0.3-0.30.5-0.40.5-0.50.51.10.4-0.40.4-0.4-1.31.1-0.5
Intermittent access total infusions0.20.20.60.4-0.40.4-0.2-0.30.4-0.40.4-0.50.40.80.3-0.30.3-0.3-0.70.8-0.4
Intermittent access day 1 locomotion1.71.82.51.3-1.31.4-1.2-1.31.3-1.31.4-1.31.31.61.4-1.41.4-1.4-0.91.5-1.4
Intermittent access day 15 total locomotion1.61.83.11.3-1.31.3-1.1-1.21.3-1.31.4-1.31.31.61.3-1.31.3-1.3-1.01.8-1.4
Intermittent access total locomotion0.00.00.30.0-0.00.0-0.00.1-0.10.00.10.0-0.00.50.1-0.10.1-0.10.20.6-0.2
Intermittent access standard deviation1.01.12.41.0-1.01.0-0.9-1.01.0-0.91.0-1.01.01.61.0-1.01.0-1.0-1.01.4-1.1
Left kidney weight2.67.28.1-2.82.8-2.72.72.9-2.72.8-2.72.8-2.8-2.5-2.82.8-2.82.81.6-2.52.6
Right kidney weight2.87.88.9-2.82.8-2.82.72.7-2.83.0-2.72.9-2.7-2.9-2.82.8-2.82.82.5-3.02.7
Cocaine induced anxiety0.10.10.40.2-0.20.2-0.6-0.20.2-0.20.2-0.10.20.40.2-0.20.2-0.20.60.2-0.3
Post-drug Anxiety1.82.02.71.5-1.51.5-1.6-1.51.5-1.51.4-1.41.51.31.4-1.41.4-1.4-0.11.2-1.4
Baseline Anxiety0.40.40.70.7-0.70.7-0.6-0.70.7-0.70.7-0.80.70.50.7-0.70.7-0.70.10.6-0.6
Tail length0.10.20.6-0.50.5-0.40.70.5-0.50.5-0.30.5-0.2-0.8-0.30.3-0.30.30.4-0.60.6
Length with tail0.83.05.0-1.71.8-1.61.81.8-1.61.8-1.61.6-1.7-2.2-1.61.6-1.61.61.5-2.11.8
Length without tail2.24.96.5-2.32.3-2.22.12.3-2.12.4-2.12.1-2.5-2.2-2.22.2-2.22.21.8-2.32.1
Times rat made contact with spout0.20.31.50.4-0.40.5-0.6-0.30.5-0.40.5-0.40.30.80.3-0.30.3-0.3-1.20.7-0.2
Lifetime Intake0.30.40.90.6-0.60.6-0.3-0.50.6-0.60.5-0.80.60.80.5-0.50.5-0.5-0.90.8-0.5
Liver weight, left0.60.91.8-0.90.9-0.80.70.9-0.80.8-0.70.8-1.0-1.3-0.90.9-0.90.91.2-1.30.9
Liver weight, right1.42.34.6-1.41.4-1.41.61.4-1.41.3-1.51.3-1.4-2.1-1.51.5-1.51.51.0-2.11.7
Locomotor activity6.410.211.0-3.33.3-3.23.23.3-3.33.3-3.23.3-3.2-3.0-3.23.2-3.23.23.0-2.92.9
Locomotor testing distance3.35.56.7-2.52.5-2.42.22.4-2.52.6-2.32.5-2.4-2.2-2.32.3-2.32.32.2-2.11.9
Locomotor testing rearing2.13.24.5-1.91.9-1.81.81.7-2.02.1-1.72.1-1.7-1.5-1.61.6-1.61.61.7-1.52.1
Locomotion in novel chamber0.81.02.90.9-0.91.0-1.1-0.90.9-0.91.1-0.70.81.00.9-0.90.9-0.9-1.71.2-1.2
Locomotion in novel chamber post-restriction0.30.41.10.6-0.60.5-0.7-0.50.4-0.60.5-0.40.40.80.5-0.50.5-0.5-1.00.7-0.6
Fecal boli incidents, locomotor time 10.00.00.2-0.00.0-0.0-0.10.1-0.10.00.0-0.1-0.10.0-0.00.0-0.00.0-0.50.1-0.0
Change in fecal boli incidents, locomotor task0.10.10.5-0.00.1-0.10.4-0.00.0-0.0-0.10.00.0-0.4-0.10.1-0.10.1-0.7-0.30.3
Time >=10cm from walls, locomotor time 10.20.20.4-0.40.4-0.50.30.5-0.50.2-0.60.4-0.6-0.4-0.50.5-0.50.50.4-0.40.4
Bouts of movement, locomotor time 10.20.21.4-0.20.3-0.20.40.4-0.20.2-0.10.4-0.4-0.4-0.20.2-0.20.2-1.2-0.40.3
Total resting periods, locomotor time 10.20.22.0-0.20.2-0.20.50.4-0.20.2-0.10.4-0.4-0.3-0.20.2-0.20.2-1.4-0.30.3
Rest time, locomotor task time 10.20.22.80.2-0.10.10.1-0.10.2-0.2-0.0-0.20.0-0.00.1-0.10.1-0.1-1.70.10.0
Distance moved, locomotor task time 10.10.21.00.3-0.30.4-0.4-0.30.3-0.10.4-0.30.40.30.3-0.30.3-0.31.00.2-0.4
Vertical activity count, locomotor time 10.10.10.90.2-0.20.2-0.5-0.10.1-0.20.3-0.10.30.40.2-0.20.2-0.21.00.4-0.4
Time >=10cm from walls, locomotor time 20.00.00.10.2-0.20.2-0.3-0.10.2-0.30.1-0.30.1-0.00.2-0.20.2-0.2-0.1-0.3-0.1
Bouts of movement, locomotor time 22.02.12.9-1.51.5-1.61.41.7-1.61.4-1.71.4-1.7-1.2-1.61.6-1.61.60.3-1.21.4
Total resting periods, locomotor time 22.32.43.2-1.61.6-1.71.61.8-1.71.5-1.81.5-1.8-1.2-1.61.6-1.61.60.3-1.21.6
Rest time, locomotor task time 20.20.32.40.5-0.50.4-0.2-0.40.5-0.50.3-0.50.20.30.4-0.40.4-0.4-1.60.5-0.3
Distance moved, locomotor task time 20.10.10.50.2-0.20.4-0.4-0.20.4-0.20.4-0.50.40.10.4-0.40.4-0.40.7-0.0-0.2
Vertical activity count, locomotor time 20.30.40.80.5-0.50.5-0.9-0.40.5-0.60.6-0.40.50.90.5-0.50.5-0.50.60.8-0.7
Light reinforcement 12.34.27.7-2.02.0-2.01.82.1-2.01.9-2.01.8-2.0-2.4-2.02.0-2.02.02.8-2.21.5
Light reinforcement 20.40.50.60.7-0.70.8-0.7-0.70.7-0.80.8-0.80.80.30.8-0.80.8-0.80.00.3-0.7
Bone: marrow area2.14.65.1-2.22.2-2.22.22.3-2.12.1-2.22.1-2.2-2.1-2.22.2-2.22.21.7-2.12.2
Bone: maximum diameter1.83.44.1-1.81.8-1.81.91.9-1.71.7-1.91.6-1.9-2.0-1.91.9-1.91.91.4-1.91.7
Bone: maximum force0.50.81.0-0.80.8-0.90.90.9-0.80.8-0.90.7-0.9-1.0-0.90.9-0.90.90.7-1.01.0
Bone: maximum moment0.10.20.4-0.50.5-0.50.60.6-0.40.4-0.50.4-0.5-0.6-0.50.5-0.50.50.4-0.60.6
Mean time between licks in bursts0.20.30.80.6-0.60.5-0.6-0.50.7-0.70.4-0.60.50.60.5-0.50.5-0.5-0.90.6-0.3
Mean num. licks in bursts1.31.52.1-1.41.4-1.31.21.3-1.41.4-1.11.4-1.3-0.9-1.21.2-1.21.21.3-1.01.1
Cd content in liver0.10.10.40.3-0.30.2-0.3-0.20.2-0.20.2-0.30.20.30.2-0.20.2-0.2-0.20.6-0.6
Co content in liver0.10.10.30.3-0.30.2-0.1-0.20.3-0.40.2-0.40.30.10.3-0.30.3-0.3-0.50.10.6
Cu content in liver0.20.30.7-0.40.4-0.50.60.4-0.30.2-0.60.2-0.4-0.7-0.60.6-0.60.6-0.3-0.80.8
Fe content in liver0.50.60.80.7-0.70.8-0.8-0.70.8-0.70.8-0.80.60.70.7-0.70.7-0.7-0.80.7-0.9
K content in liver2.02.02.5-1.51.5-1.41.31.5-1.51.4-1.31.5-1.4-1.5-1.31.3-1.31.31.4-1.61.4
Mg content in liver3.73.85.1-2.02.0-2.01.91.9-2.01.9-1.92.0-1.8-2.0-1.91.9-1.91.91.7-2.02.3
Mn content in liver0.00.00.2-0.10.1-0.10.00.1-0.10.0-0.10.2-0.1-0.1-0.20.2-0.20.2-0.1-0.10.4
Na content in liver2.22.33.7-1.51.5-1.51.51.4-1.51.3-1.41.5-1.6-1.8-1.51.5-1.51.51.3-1.91.9
Rb content in liver1.72.12.8-1.51.5-1.61.61.5-1.51.5-1.71.4-1.4-1.5-1.41.4-1.41.41.4-1.21.1
Se content in liver0.40.51.00.6-0.60.7-0.8-0.70.6-0.60.8-0.50.60.60.7-0.70.7-0.7-0.30.7-1.0
Sr content in liver0.00.00.10.1-0.10.1-0.2-0.20.1-0.20.2-0.10.10.10.2-0.20.2-0.20.20.0-0.3
Zn content in liver0.40.40.80.6-0.60.7-0.7-0.60.6-0.70.7-0.60.70.60.6-0.60.6-0.6-0.90.5-0.4
Bone: minimum diameter0.00.00.10.0-0.00.1-0.10.00.10.00.2-0.0-0.00.20.0-0.00.0-0.00.00.10.3
Time in familiar zone, hab. session 10.10.10.30.3-0.30.3-0.3-0.40.3-0.30.3-0.20.4-0.00.4-0.40.4-0.40.50.2-0.6
Time in novel zone, hab. session 10.10.10.80.1-0.10.00.00.10.1-0.1-0.0-0.1-0.10.2-0.10.1-0.10.1-0.90.10.2
Total zone transitions, hab. session 10.81.11.71.2-1.21.1-1.0-1.11.2-1.21.0-1.21.10.71.1-1.11.1-1.1-1.30.8-0.4
Total locomotion distance, hab. session 10.10.10.30.4-0.40.4-0.4-0.40.4-0.50.4-0.50.40.10.3-0.30.3-0.3-0.50.20.3
Locomotion velocity, hab. session 10.00.10.70.1-0.10.1-0.2-0.00.1-0.20.2-0.10.1-0.00.0-0.00.0-0.0-0.4-0.00.8
Time in familiar zone, hab. session 20.10.10.20.3-0.30.1-0.1-0.40.3-0.30.0-0.30.40.10.2-0.20.2-0.20.20.0-0.4
Time in novel zone, hab. session 20.00.00.10.0-0.00.2-0.2-0.00.10.00.30.0-0.00.30.3-0.30.3-0.3-0.30.3-0.1
Total zone transitions, hab. session 20.10.10.6-0.10.1-0.20.30.2-0.10.0-0.4-0.0-0.2-0.8-0.30.3-0.30.30.1-0.70.4
Total locomotion distance, hab. session 20.50.71.1-0.80.8-0.80.70.9-0.70.7-0.80.7-0.9-1.0-1.01.0-1.01.00.7-1.01.0
Locomotion velocity, hab. session 20.20.30.6-0.50.5-0.50.40.6-0.40.4-0.50.4-0.6-0.8-0.70.7-0.70.70.3-0.70.7
Novel to familiar place preference ratio1.31.42.2-1.31.3-1.21.21.1-1.31.4-1.11.4-1.2-0.9-0.90.9-0.90.91.3-0.91.5
Novelty place preference1.31.42.2-1.31.3-1.21.21.1-1.31.3-1.21.4-1.2-1.0-0.90.9-0.90.91.3-1.01.5
Time in novel zone, NPP test1.61.62.2-1.41.4-1.31.31.2-1.41.5-1.31.5-1.3-1.1-1.01.0-1.01.01.5-1.11.5
Total zone transitions, NPP test0.10.10.5-0.30.3-0.20.20.3-0.30.3-0.20.3-0.3-0.7-0.20.2-0.20.20.3-0.60.2
Total locomotion distance, NPP test0.40.61.0-0.80.8-0.70.60.7-0.80.8-0.60.9-0.7-1.0-0.70.7-0.70.70.8-0.90.9
Locomotion velocity, NPP test0.10.20.5-0.50.5-0.40.30.4-0.40.5-0.30.5-0.4-0.6-0.40.4-0.40.40.3-0.60.7
Intraocular pressure0.10.10.5-0.10.1-0.40.50.2-0.2-0.0-0.5-0.0-0.0-0.2-0.60.6-0.60.6-0.70.10.2
Delta distance traveled before/after self-admin0.80.82.1-0.80.8-0.70.80.7-0.80.8-0.70.8-0.8-1.4-0.70.7-0.70.71.5-1.31.0
Delta ambulatory time before/after self-admin0.30.31.7-0.40.4-0.30.40.3-0.40.4-0.30.4-0.4-1.0-0.20.2-0.20.21.3-0.90.5
Parametrial fat weight0.00.10.30.1-0.10.00.2-0.00.2-0.2-0.1-0.50.3-0.5-0.20.2-0.20.2-0.1-0.30.3
Pavlov. Cond. lever latency0.10.10.70.3-0.30.00.1-0.30.2-0.3-0.1-0.30.30.4-0.20.2-0.20.2-0.90.4-0.1
Pavlov. Cond. magazine entry latency0.91.21.61.1-1.11.2-1.1-1.21.1-1.11.2-1.11.20.71.3-1.31.3-1.3-0.70.7-0.3
Pavlov. Cond. change in total contacts0.10.10.3-0.10.10.2-0.30.10.00.20.40.1-0.3-0.10.3-0.30.3-0.30.6-0.0-0.4
Pavlov. Cond. index score0.70.91.40.9-0.91.1-1.1-0.91.0-0.91.2-0.90.90.61.2-1.21.2-1.2-0.40.6-0.5
Pavlov. Cond. latency score0.40.50.90.6-0.60.8-0.9-0.60.7-0.50.9-0.60.60.20.9-0.90.9-0.90.00.2-0.3
Pavlov. Cond. lever contacts0.10.10.30.2-0.20.4-0.5-0.20.3-0.20.5-0.30.2-0.10.5-0.50.5-0.50.4-0.1-0.3
Pavlov. Cond. magazine entry number1.21.51.9-1.21.2-1.41.31.2-1.31.2-1.41.3-1.2-0.9-1.41.4-1.41.41.0-1.00.7
Pavlov. Cond. intertrial magazine entries0.10.10.8-0.20.2-0.30.30.0-0.30.3-0.40.2-0.1-0.5-0.30.3-0.30.30.9-0.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.50.71.10.8-0.80.9-0.9-0.80.8-0.71.0-0.80.80.41.1-1.11.1-1.1-0.30.4-0.4
Pavlov. Cond. response bias0.60.71.10.8-0.81.0-1.0-0.80.8-0.71.0-0.80.80.51.0-1.01.0-1.0-0.30.5-0.6
Pavlov. Cond. lever latency0.91.21.4-1.11.1-1.11.21.1-1.11.1-1.11.1-1.1-0.7-1.21.2-1.21.20.9-0.81.0
Pavlov. Cond. magazine entry latency3.54.04.82.0-2.02.1-2.2-2.02.1-2.02.2-2.02.01.72.1-2.12.1-2.1-1.81.8-1.7
Pavlov. Cond. change in total contacts0.40.60.80.8-0.80.8-0.9-0.70.7-0.80.8-0.70.70.60.8-0.80.8-0.8-0.70.7-0.6
Pavlov. Cond. index score1.21.51.91.3-1.31.3-1.4-1.31.3-1.21.3-1.21.30.91.3-1.31.3-1.3-1.11.0-1.0
Pavlov. Cond. latency score0.81.01.31.0-1.01.0-1.1-1.01.0-1.01.1-1.01.00.61.1-1.11.1-1.1-0.80.7-0.8
Pavlov. Cond. lever contacts0.30.40.60.7-0.60.7-0.8-0.70.6-0.70.7-0.60.70.40.8-0.80.8-0.8-0.40.4-0.6
Pavlov. Cond. magazine entry number3.34.04.4-2.12.1-2.02.12.1-2.02.1-2.02.1-2.1-1.7-2.02.0-2.02.01.9-1.81.6
Pavlov. Cond. intertrial magazine entries0.60.81.8-0.90.9-0.90.90.8-0.80.9-0.90.9-0.9-0.8-0.80.8-0.80.81.4-1.00.6
Pavlov. Cond. lever-magazine prob. diff.1.31.72.01.3-1.31.3-1.4-1.41.3-1.31.3-1.31.40.91.4-1.41.4-1.4-1.21.0-1.1
Pavlov. Cond. response bias1.21.61.91.3-1.31.3-1.4-1.31.2-1.31.3-1.21.31.01.4-1.41.4-1.4-1.21.1-0.9
Time in closed arm before self-admin0.10.10.6-0.10.1-0.0-0.30.1-0.00.1-0.00.1-0.20.50.1-0.10.1-0.10.10.8-0.3
Time in closed arm after self-admin0.10.11.3-0.00.0-0.00.20.0-0.00.1-0.10.0-0.10.6-0.00.0-0.00.0-1.10.6-0.1
Time in open arm before self-admin0.90.91.7-0.90.9-0.90.90.9-1.00.9-0.90.9-0.7-0.8-1.11.1-1.11.10.9-1.30.9
Time in open arm after self-admin0.00.00.30.2-0.20.1-0.3-0.20.1-0.20.2-0.10.1-0.20.1-0.10.1-0.10.0-0.5-0.0
Bone: periosteal estimation1.12.42.8-1.51.5-1.51.51.6-1.41.4-1.51.4-1.6-1.7-1.61.6-1.61.61.2-1.71.6
Bone: periosteal perimeter1.83.03.6-1.71.7-1.71.71.8-1.61.6-1.71.6-1.8-1.9-1.81.8-1.81.81.5-1.91.6
Bone: post-yield work0.10.20.5-0.40.4-0.40.40.5-0.40.4-0.40.4-0.4-0.4-0.40.4-0.40.40.7-0.20.4
Progressive ratio test 1 active lever presses0.20.20.3-0.40.4-0.50.50.5-0.40.4-0.60.3-0.4-0.3-0.60.6-0.60.60.2-0.10.5
Progressive ratio test 1 breakpoint0.00.00.1-0.00.0-0.10.10.1-0.1-0.0-0.2-0.0-0.00.1-0.20.2-0.20.2-0.10.30.0
Progressive ratio test 1 inactive lever presses1.01.11.91.2-1.21.1-1.1-1.21.2-1.30.9-1.41.20.90.9-0.90.9-0.9-0.30.9-1.0
Progressive ratio test 2 active lever presses0.30.30.6-0.50.5-0.60.80.6-0.50.6-0.60.5-0.5-0.2-0.60.6-0.60.60.8-0.20.5
Progressive ratio test 2 breakpoint0.50.50.9-0.70.7-0.71.00.7-0.70.7-0.70.6-0.7-0.4-0.70.7-0.70.70.9-0.50.7
Progressive ratio test 2 inactive lever presses0.40.51.00.7-0.70.7-0.7-0.50.7-0.60.7-0.80.61.00.7-0.70.7-0.7-0.30.9-0.8
Incentive Sensitization - Responses0.40.40.9-0.70.7-0.60.80.7-0.70.7-0.60.6-0.7-0.4-0.60.6-0.60.60.9-0.50.6
Incentive Sensitization - Breakpoint0.20.20.6-0.50.5-0.40.60.5-0.50.6-0.40.5-0.5-0.2-0.40.4-0.40.40.8-0.30.4
Sum of active levers in priming session hrs 5-60.00.00.1-0.20.1-0.10.20.1-0.20.2-0.10.1-0.1-0.2-0.00.0-0.00.00.20.00.1
Progressive ratio0.50.52.00.6-0.60.6-0.8-0.50.7-0.40.6-0.70.61.20.3-0.30.3-0.3-1.41.2-0.8
Food seeking constrained by brief footshock0.50.60.8-0.80.8-0.80.90.6-0.70.8-0.90.6-0.6-0.9-0.90.9-0.90.90.8-0.80.9
Seeking ratio, punishment vs. effort2.83.46.3-1.71.8-1.81.91.6-1.81.6-1.81.8-1.6-2.5-1.51.5-1.51.52.3-2.42.0
Retroperitoneal fat weight0.00.10.5-0.20.2-0.10.10.20.00.2-0.2-0.1-0.3-0.7-0.30.3-0.30.30.6-0.60.3
Reaction time number correct1.82.53.2-1.61.6-1.71.81.6-1.61.6-1.71.6-1.6-1.4-1.71.7-1.71.71.6-1.31.1
Reaction time mean minus median0.20.30.50.4-0.40.6-0.4-0.70.4-0.10.7-0.30.40.00.7-0.70.7-0.7-0.4-0.1-0.3
Reaction time mean minus median AUC0.91.11.71.1-1.11.2-1.0-1.31.0-0.81.3-1.01.10.51.3-1.31.3-1.3-0.80.4-1.1
Reaction time num false alarms0.81.12.21.1-1.11.0-1.2-1.01.2-1.30.9-1.11.00.80.8-0.80.8-0.8-1.50.8-1.1
Reaction time num false alarms AUC0.30.40.80.7-0.70.6-0.8-0.60.8-0.80.6-0.80.60.30.5-0.50.5-0.5-0.70.3-0.9
Reaction time trials correct on left1.82.53.2-1.61.6-1.71.81.6-1.61.6-1.71.6-1.6-1.4-1.71.7-1.71.71.6-1.31.1
Reaction time trials on left1.92.73.4-1.71.7-1.71.81.6-1.71.7-1.81.6-1.6-1.5-1.71.7-1.71.71.6-1.41.1
Reaction time mean3.04.16.32.1-2.12.1-1.9-2.22.1-2.02.1-2.02.11.52.1-2.12.1-2.1-2.51.6-1.4
Reaction time mean AUC2.22.94.21.8-1.81.8-1.6-1.91.7-1.61.8-1.71.71.31.8-1.81.8-1.8-2.01.3-1.3
Median of all reaction times4.25.88.82.5-2.52.5-2.3-2.52.5-2.52.4-2.42.52.02.4-2.42.4-2.4-3.02.1-1.8
Reaction time omissions0.30.40.7-0.60.6-0.70.90.7-0.70.5-0.70.6-0.7-0.7-0.60.6-0.60.6-0.6-0.70.4
Reaction time false alarm rate1.72.43.31.6-1.61.6-1.8-1.51.7-1.71.5-1.71.51.21.4-1.41.4-1.4-1.61.2-1.5
Reaction time premature initiation rate1.62.23.0-1.41.4-1.51.61.4-1.41.4-1.61.4-1.5-1.7-1.51.5-1.51.51.2-1.51.0
Reaction time premature initiations2.94.05.2-2.02.0-2.12.31.9-1.92.0-2.21.9-2.0-2.2-2.12.1-2.12.11.7-2.01.4
Std. dev. reaction times1.11.52.61.3-1.21.4-1.1-1.41.2-1.01.4-1.11.20.81.4-1.41.4-1.4-1.60.7-0.7
Reaction time trials completed1.92.73.4-1.71.7-1.71.81.6-1.71.7-1.81.6-1.6-1.5-1.71.7-1.71.71.6-1.41.1
Reaction time trials AUC1.52.22.9-1.51.5-1.61.71.5-1.51.5-1.61.5-1.5-1.3-1.61.6-1.61.61.4-1.21.0
Run reversals in cocaine runway, females0.00.00.1-0.00.0-0.10.20.1-0.1-0.0-0.10.10.10.1-0.30.3-0.30.3-0.40.00.0
Run reversals in cocaine runway, males0.00.00.20.0-0.0-0.00.1-0.10.0-0.2-0.1-0.00.1-0.4-0.00.0-0.00.00.2-0.10.1
Latency to leave start box in cocaine runway2.83.14.3-1.81.8-1.91.51.8-2.01.7-1.82.0-1.9-1.4-1.71.7-1.71.72.1-1.51.5
Latency to leave start box in cocaine runway, F0.60.61.9-0.80.8-0.90.40.8-1.00.8-0.80.9-0.9-0.5-0.70.7-0.70.71.4-0.60.5
Latency to leave start box in cocaine runway, M4.14.04.9-2.02.0-2.12.12.0-2.11.9-2.12.2-2.0-1.6-2.12.1-2.12.10.9-1.82.0
Std. dev. time between licks in bursts0.30.31.1-0.50.5-0.50.40.5-0.50.4-0.50.5-0.5-0.8-0.40.4-0.40.40.9-0.81.0
Total sessions with >9 infusions0.00.00.10.3-0.30.20.1-0.20.3-0.30.1-0.40.30.10.1-0.10.1-0.1-0.2-0.0-0.0
Short access day 1 total inactive lever presses0.10.10.40.5-0.50.4-0.3-0.40.5-0.60.3-0.70.50.20.2-0.20.2-0.2-0.10.2-0.2
Short access day 10 total inactive lever presses0.60.71.40.9-0.90.7-1.2-0.70.8-0.90.7-0.80.71.10.7-0.70.7-0.7-0.01.2-1.1
Short access day 1 total infusions0.30.31.00.6-0.60.5-0.2-0.40.6-0.60.4-0.80.50.70.3-0.30.3-0.3-1.00.6-0.3
Short access day 10 total infusions0.30.41.70.6-0.60.5-0.1-0.60.6-0.60.5-0.70.60.60.5-0.50.5-0.5-1.30.5-0.3
Short access total infusions0.80.91.51.0-1.00.9-0.5-0.91.1-1.00.8-1.21.00.90.8-0.80.8-0.8-1.20.8-0.7
Short access day 1 locomotion0.10.10.40.3-0.30.1-0.1-0.10.3-0.4-0.0-0.40.20.3-0.10.1-0.10.1-0.60.2-0.1
Short access day 10 total locomotion0.00.00.0-0.00.0-0.00.20.0-0.00.0-0.00.0-0.0-0.1-0.00.0-0.00.0-0.1-0.20.1
Short access total locomotion0.80.91.21.0-1.00.9-0.8-0.91.0-1.00.9-1.10.91.00.9-0.90.9-0.9-1.10.8-0.9
One hour access (0.3 mA shock)0.20.20.4-0.40.4-0.40.60.5-0.30.3-0.50.2-0.4-0.1-0.50.5-0.50.5-0.2-0.00.4
Compulsive drug intake0.30.30.7-0.40.4-0.50.60.4-0.40.3-0.60.3-0.5-0.8-0.50.5-0.50.5-0.1-0.80.7
One hour access (shock baseline)0.20.30.90.4-0.50.4-0.4-0.30.5-0.40.4-0.60.40.90.3-0.30.3-0.3-0.60.9-0.5
Social response proportion0.10.10.40.1-0.10.4-0.5-0.00.2-0.00.5-0.10.10.40.3-0.30.3-0.30.50.3-0.7
Social responses0.10.10.9-0.30.30.00.00.3-0.10.30.20.3-0.1-0.50.1-0.10.1-0.10.9-0.40.3
Social time0.10.11.2-0.40.4-0.10.30.4-0.20.60.00.3-0.3-0.0-0.10.1-0.10.11.1-0.0-0.2
Soleus weight16.347.750.3-7.07.0-7.07.06.9-6.96.9-6.96.9-6.8-7.0-6.86.8-6.86.86.6-7.17.0
Bone: stiffness1.32.02.8-1.41.4-1.41.41.4-1.41.4-1.41.4-1.4-1.4-1.41.4-1.41.41.7-1.31.5
Tibialis anterior weight12.542.944.9-6.66.6-6.66.76.6-6.56.5-6.66.4-6.6-6.5-6.76.7-6.76.75.7-6.76.6
Time to tail flick, vehicle, before self-admin0.20.20.30.4-0.40.5-0.4-0.40.5-0.40.6-0.30.4-0.00.6-0.60.6-0.6-0.20.2-0.3
Time to tail flick, vehicle, after self-admin0.10.10.40.0-0.00.0-0.10.10.00.10.10.1-0.10.60.0-0.00.0-0.0-0.60.7-0.3
Time to tail flick, test, before self-admin0.90.91.01.0-1.01.0-0.9-0.90.9-1.01.0-0.80.90.91.0-1.01.0-1.0-1.00.8-0.9
Time to tail flick, test, after self-admin0.80.93.40.8-0.80.7-1.2-0.80.7-0.70.6-0.70.81.90.7-0.70.7-0.70.21.5-1.2
Delta time to tail flick, vehicle, before/after SA0.10.10.50.1-0.10.1-0.2-0.10.0-0.10.1-0.00.00.70.0-0.00.0-0.0-0.40.5-0.3
Delta time to tail flick, test, before/after SA0.20.21.1-0.30.3-0.4-0.00.2-0.40.4-0.40.3-0.30.3-0.40.4-0.40.41.00.10.1
Tibia length0.10.20.40.3-0.30.5-0.5-0.20.4-0.20.5-0.30.20.40.5-0.50.5-0.5-0.10.6-0.6
Ambulatory time before self-admin0.10.11.1-0.00.0-0.10.10.2-0.00.0-0.2-0.1-0.00.6-0.30.3-0.30.3-1.00.6-0.1
Ambulatory time after self-admin0.50.60.7-0.70.7-0.80.80.8-0.80.8-0.80.6-0.7-0.7-0.80.8-0.80.80.4-0.80.8
Bone: tissue strength1.51.52.41.2-1.21.2-1.2-1.21.1-1.11.2-1.11.21.41.3-1.31.3-1.3-0.51.2-1.6
Total heroin consumption2.52.94.0-1.71.7-1.92.01.6-1.91.8-1.91.8-1.7-1.4-1.81.8-1.81.81.1-1.31.7
Bone: trabecular number1.82.83.91.7-1.71.7-1.7-1.71.7-1.61.7-1.71.71.41.7-1.71.7-1.7-1.31.6-2.0
Bone: trabecular spacing0.00.00.1-0.10.1-0.20.20.2-0.20.1-0.20.1-0.2-0.1-0.20.2-0.20.20.3-0.2-0.1
Bone: trabecular thickness0.30.31.20.6-0.60.6-0.5-0.40.6-0.60.6-0.60.50.50.5-0.50.5-0.5-1.10.6-0.3
Bone: trabecular tissue density5.17.28.1-2.72.7-2.82.82.5-2.72.6-2.82.6-2.6-2.8-2.62.6-2.62.62.7-2.92.5
Water consumed over 24 hours0.40.51.60.6-0.60.7-0.8-0.50.7-0.50.8-0.60.50.80.5-0.50.5-0.5-1.20.8-0.1
Number of responses in last shaping day0.00.00.10.1-0.10.1-0.2-0.10.0-0.00.20.00.10.30.1-0.10.1-0.10.20.3-0.3