Hub : Genes

Eml3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Eml3 0.29 0.14 1.5e-06 0.22 0.2 0.2 0.24 6.4e-06 2.0e-05 1.8e-05 1.6e-06
2 IC gene expression Eml3 0.18 0.1 2.0e-07 0.15 0.12 0.12 0.12 7.5e-07 1.1e-05 6.8e-06 8.3e-06
3 Adipose gene expression Eml3 0.83 0.08 0.0e+00 0.47 0.48 0.5 0.49 2.4e-58 5.4e-60 5.3e-64 2.9e-62
4 LHb gene expression Eml3 0.61 0.13 3.1e-14 0.24 0.33 0.33 0.27 2.2e-06 1.3e-08 9.9e-09 4.3e-07
5 Adipose mRNA stability Eml3 0.19 0.1 1.8e-15 0.11 0.1 0.1 0.1 6.2e-12 3.7e-11 5.3e-11 1.1e-11
6 NAcc intron excision ratio chr1_215258766_215258917 0.02 0.01 6.6e-04 0.02 0.02 0.02 0.02 2.5e-04 7.1e-04 7.2e-04 8.2e-04
7 IL gene expression Eml3 0.2 0.11 1.4e-04 0.14 0.13 0.13 0.12 2.7e-04 5.8e-04 5.5e-04 6.7e-04
8 pVTA gene expression Eml3 0.29 0.23 0.0e+00 0.26 0.23 0.25 0.26 7.3e-21 1.8e-18 8.0e-20 1.2e-20
9 pVTA intron excision ratio chr1_215257259_215258699 0.03 0.02 5.4e-03 0.02 0.03 0.01 0.02 4.6e-03 4.1e-03 3.8e-02 1.2e-02
10 pVTA mRNA stability Eml3 0.08 0.05 2.0e-08 0.09 0.09 0.09 0.09 8.3e-08 7.9e-08 6.2e-08 9.7e-08
11 NAcc gene expression Eml3 0.2 0.09 0.0e+00 0.31 0.31 0.31 0.31 2.6e-48 3.2e-48 5.7e-48 2.0e-48
12 Brain gene expression Eml3 0.53 0.13 0.0e+00 0.4 0.4 0.41 0.41 2.3e-39 4.6e-40 6.7e-41 4.6e-41
13 BLA gene expression Eml3 0.22 0.11 1.6e-13 0.22 0.25 0.25 0.24 7.4e-12 1.4e-13 2.5e-13 3.6e-13
14 pVTA intron excision ratio chr1_215259436_215259604 0.03 0.02 1.3e-03 0.04 0.04 0.03 0.04 1.8e-04 5.6e-04 1.3e-03 4.0e-04
15 NAcc mRNA stability Eml3 0.02 0.01 4.9e-03 0.01 0.01 0.01 0.01 1.7e-03 5.6e-03 2.5e-02 3.6e-03
16 PL gene expression Eml3 0.3 0.15 0.0e+00 0.25 0.23 0.25 0.24 3.6e-27 3.0e-25 1.3e-26 1.8e-26
17 Liver gene expression Eml3 0.6 0.12 0.0e+00 0.38 0.4 0.42 0.4 6.2e-45 3.7e-47 5.1e-51 1.6e-47
18 RMTg gene expression Eml3 0.46 0.15 1.8e-10 0.24 0.24 0.25 0.23 5.3e-07 3.6e-07 3.4e-07 7.6e-07
19 NAcc intron excision ratio chr1_215259436_215259604 0.02 0.02 9.8e-04 0.01 0.02 0.02 0.02 2.2e-03 4.4e-04 5.7e-04 7.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.30.41.2-0.6-0.7-0.5-0.3-0.5-0.7-0.6-0.6-0.90.6-0.7-0.6-0.90.50.7-0.7-0.4-0.51.1
Area under the delay curve0.20.20.5-0.1-0.1-0.4-0.1-0.4-0.4-0.4-0.4-0.40.4-0.4-0.4-0.50.50.4-0.4-0.6-0.50.7
BMI with tail2.58.516.5-2.7-2.5-3.5-1.4-2.6-2.6-2.6-2.6-3.42.9-3.1-2.7-3.62.92.6-2.6-3.4-2.54.1
BMI without tail0.82.44.0-1.2-0.9-1.5-0.9-1.6-1.4-1.5-1.5-1.61.6-1.7-1.6-1.81.81.3-1.3-1.9-1.72.0
Body weight3.515.421.2-4.0-3.6-4.6-2.9-3.9-3.8-3.9-3.9-4.23.9-4.1-3.8-4.34.03.5-3.5-4.3-3.54.5
Weight adjusted by age0.50.71.2-1.1-0.9-1.0-0.8-0.9-0.7-0.6-0.6-1.00.8-1.0-0.9-0.90.61.0-1.0-0.7-0.60.9
Bone surface1.73.04.6-2.1-2.1-2.0-1.1-1.5-1.7-1.7-1.7-2.11.7-1.7-1.6-2.01.51.6-1.6-1.4-1.22.1
Bone volume0.51.02.0-1.3-1.3-1.2-0.4-0.8-1.0-0.9-0.9-1.40.9-0.9-0.8-1.30.70.9-0.9-0.6-0.51.4
Breakpoint value in progressive ratio session1.61.92.9-1.6-1.7-1.6-1.7-1.2-1.4-1.3-1.3-1.41.6-1.2-1.3-1.21.61.4-1.4-1.3-1.00.9
Number of licking bursts0.00.00.2-0.20.1-0.2-0.0-0.2-0.4-0.3-0.3-0.00.0-0.1-0.1-0.10.10.1-0.10.1-0.10.1
Context. condit. distance diff. score0.10.10.80.90.50.40.60.50.00.10.10.3-0.30.30.40.1-0.3-0.30.3-0.00.00.1
Locomotion velocity, session 10.10.20.50.3-0.1-0.1-0.3-0.3-0.4-0.4-0.4-0.20.1-0.4-0.4-0.40.20.6-0.6-0.5-0.70.4
Locomotion distance, session 10.91.21.9-0.4-0.9-0.8-0.7-0.9-1.2-1.4-1.4-1.11.0-1.1-1.0-1.21.01.1-1.1-1.2-1.21.4
Locomotion velocity, session 22.73.24.5-1.7-1.9-1.8-1.4-1.6-1.8-1.9-1.9-1.92.0-1.7-1.6-1.91.91.6-1.6-2.1-1.51.9
Locomotion distance, session 20.40.61.3-0.3-0.6-0.6-0.6-0.6-0.9-1.0-1.0-0.70.9-0.7-0.7-0.71.00.7-0.7-1.1-0.90.7
Locomotion velocity, session 30.60.71.9-0.4-0.5-0.8-0.2-0.7-0.9-0.8-0.8-0.90.7-0.9-0.8-1.10.70.7-0.7-0.9-0.91.4
Locomotion distance, session 30.20.20.4-0.3-0.0-0.5-0.5-0.6-0.4-0.3-0.3-0.20.2-0.6-0.6-0.40.10.5-0.5-0.4-0.70.4
Stereotopy head waving bouts, day 30.10.21.00.60.30.21.00.4-0.2-0.2-0.2-0.20.20.30.4-0.30.4-0.40.4-0.30.20.7
Stereotopy head waving duration, day 30.10.10.50.60.10.20.70.4-0.4-0.4-0.4-0.20.30.20.3-0.30.5-0.30.3-0.4-0.00.5
Locomotion velocity, session 70.10.10.20.2-0.2-0.10.50.2-0.4-0.3-0.3-0.20.30.10.1-0.20.3-0.20.2-0.30.10.4
Locomotion distance, session 70.00.10.20.30.3-0.10.2-0.2-0.2-0.1-0.1-0.10.2-0.2-0.1-0.30.20.1-0.1-0.5-0.40.5
Stereotopy head waving bouts, day 70.10.10.3-0.4-0.6-0.10.20.0-0.5-0.5-0.5-0.50.3-0.00.0-0.40.30.0-0.0-0.10.20.5
Stereotopy head waving duration, day 71.21.52.3-1.4-1.5-1.1-0.9-1.1-1.4-1.4-1.4-1.41.3-1.1-1.0-1.31.31.0-1.0-1.0-0.91.3
Locomotion velocity, session 80.10.10.30.40.10.0-0.3-0.2-0.4-0.3-0.30.00.3-0.1-0.2-0.10.40.2-0.2-0.6-0.60.1
Locomotion distance, session 80.10.20.80.90.50.20.90.6-0.00.00.00.2-0.20.40.50.0-0.2-0.50.5-0.10.20.3
Degree of sensitization distance0.10.10.50.20.1-0.20.70.1-0.1-0.1-0.1-0.30.10.00.2-0.40.2-0.20.2-0.30.00.7
Degree of sensitization stereotypy0.50.51.3-1.1-1.1-0.6-0.4-0.5-0.8-0.9-0.9-1.00.8-0.5-0.5-0.80.80.5-0.5-0.5-0.20.8
Conditioned locomotion0.70.81.2-0.8-0.8-0.9-0.8-0.8-0.9-0.9-0.9-0.91.0-0.8-0.8-0.91.00.8-0.8-1.1-0.80.9
Cocaine response after cond. corrected0.20.21.31.20.70.40.40.40.10.10.10.5-0.40.40.40.3-0.4-0.20.2-0.1-0.1-0.2
Cocaine response after cond. not corrected0.20.20.80.90.50.40.40.40.40.30.30.5-0.60.40.40.3-0.6-0.20.20.20.1-0.2
Cocaine response before conditioning0.10.10.8-0.9-0.7-0.1-0.4-0.30.40.40.4-0.3-0.1-0.3-0.2-0.1-0.30.2-0.20.50.3-0.1
Saline control response3.54.76.4-2.2-2.0-2.5-2.2-2.4-2.2-2.2-2.2-1.92.0-2.3-2.3-2.02.02.1-2.1-2.2-2.21.8
Bone: connectivity density1.62.64.2-1.6-1.7-1.5-1.2-1.5-1.5-1.4-1.4-1.91.6-1.7-1.6-1.91.51.6-1.6-1.4-1.42.0
Bone: cortical apparent density0.20.30.7-0.4-0.8-0.2-0.8-0.4-0.9-0.8-0.8-0.40.6-0.3-0.4-0.30.50.5-0.5-0.3-0.50.1
Bone: cortical area0.60.91.8-1.4-1.2-1.2-0.7-1.0-0.9-0.9-0.9-1.10.9-1.0-0.9-1.00.80.8-0.8-0.7-0.51.0
Bone: cortical porosity0.10.10.30.20.10.2-0.00.4-0.1-0.1-0.10.20.10.50.30.40.2-0.30.3-0.10.3-0.6
Bone: cortical porosity0.10.10.2-0.0-0.2-0.1-0.30.0-0.4-0.3-0.3-0.00.40.1-0.00.10.50.1-0.1-0.4-0.1-0.2
Bone: cortical thickness3.25.37.9-2.5-2.5-2.0-2.8-2.6-2.3-2.4-2.4-2.02.3-2.4-2.5-2.02.22.4-2.4-2.0-2.31.6
Bone: cortical thickness0.60.71.5-0.6-0.7-0.5-1.2-1.0-0.8-0.9-0.9-0.50.6-0.9-1.0-0.60.61.0-1.0-0.7-1.10.4
Bone: cortical tissue density0.40.51.1-0.6-0.9-0.4-0.9-0.5-1.0-1.0-1.0-0.60.8-0.5-0.6-0.40.70.6-0.6-0.4-0.60.2
Condit. Reinf. active minus inactive responses0.91.01.3-1.0-1.1-0.9-1.0-0.9-0.9-0.9-0.9-1.11.0-1.0-1.0-1.10.91.1-1.1-0.8-0.91.0
Condit. Reinf. active-inactive response ratio0.40.40.9-0.5-0.7-0.4-0.9-0.5-0.7-0.7-0.7-0.60.6-0.7-0.7-0.60.60.9-0.9-0.5-0.80.5
Condit. Reinf. active responses0.50.61.2-1.0-1.1-0.8-0.5-0.6-0.6-0.7-0.7-1.10.9-0.8-0.7-1.00.80.7-0.7-0.7-0.41.0
Condit. Reinf. inactive responses0.10.20.6-0.10.10.00.80.40.60.40.4-0.1-0.30.30.40.0-0.3-0.50.50.30.80.2
Incentive salience index mean1.11.42.0-1.3-1.3-1.2-1.0-1.1-1.1-1.1-1.1-1.31.1-1.3-1.2-1.41.01.2-1.2-1.0-1.01.4
Condit. Reinf. lever presses0.81.11.9-1.3-1.2-1.2-0.6-1.1-1.0-1.0-1.0-1.20.8-1.2-1.0-1.30.71.0-1.0-0.9-0.81.4
Condit. Reinf. active minus inactive responses0.40.51.00.30.30.70.70.70.50.50.50.5-0.50.80.80.7-0.6-0.90.90.81.0-0.7
Condit. Reinf. active-inactive response ratio1.11.32.90.70.61.11.71.40.90.90.90.6-0.71.31.50.9-0.8-1.51.51.01.7-0.7
Condit. Reinf. active responses0.00.00.2-0.4-0.3-0.2-0.2-0.2-0.3-0.3-0.3-0.20.1-0.2-0.1-0.1-0.0-0.00.0-0.00.0-0.0
Condit. Reinf. inactive responses0.40.61.5-0.6-0.4-0.9-1.2-1.1-0.7-0.6-0.6-0.30.3-1.0-1.0-0.50.20.9-0.9-0.6-1.10.3
Condit. Reinf. lever presses0.60.81.8-1.4-1.1-1.3-0.7-1.0-0.7-0.7-0.7-1.00.7-1.0-0.9-1.00.60.8-0.8-0.8-0.51.0
Condit. Reinf. lever reinforcers received0.10.10.4-0.6-0.6-0.4-0.4-0.4-0.5-0.4-0.4-0.30.3-0.3-0.3-0.20.20.2-0.2-0.2-0.10.1
Conditioned reinforcement - actives0.61.02.10.70.51.31.01.31.11.11.10.6-0.90.90.90.9-0.8-1.01.01.51.4-0.8
Conditioned reinforcement - inactives0.30.41.10.40.20.71.00.90.70.70.70.1-0.50.40.60.3-0.6-0.60.60.91.1-0.0
Conditioned locomotion2.33.05.22.11.72.12.32.11.71.71.71.3-1.61.61.71.3-1.6-1.71.71.61.7-0.9
Patch foraging indifference point 0 sec0.61.01.5-0.9-0.9-1.2-0.8-1.0-1.2-1.2-1.2-1.00.9-0.9-0.9-1.01.00.9-0.9-1.1-0.91.0
Patch foraging indifference point AUC0.60.82.4-1.4-1.5-1.3-0.9-0.7-0.9-0.9-0.9-1.11.1-0.6-0.6-0.80.90.7-0.7-0.7-0.20.6
Delay disc. indifference point, 0s delay0.10.10.50.70.70.30.70.20.30.20.20.2-0.30.10.2-0.0-0.2-0.20.2-0.0-0.00.3
Delay disc. indifference point, 16s delay0.10.10.3-0.3-0.3-0.30.1-0.2-0.2-0.2-0.2-0.40.2-0.3-0.2-0.40.20.2-0.2-0.2-0.10.5
Delay disc. indifference point, 2s delay0.20.30.80.50.50.40.90.50.60.70.70.3-0.50.40.50.2-0.5-0.50.50.40.50.0
Delay disc. indifference point, 24s delay0.30.30.6-0.3-0.3-0.5-0.5-0.6-0.5-0.5-0.5-0.40.5-0.6-0.6-0.60.50.6-0.6-0.6-0.80.6
Delay disc. indifference point, 4s delay0.90.91.6-0.4-0.4-0.8-0.7-1.0-1.0-0.9-0.9-0.80.9-1.0-1.0-1.01.11.0-1.0-1.2-1.31.2
Delay disc. indifference point, 8s delay0.10.10.50.70.70.40.20.20.10.10.10.4-0.20.20.20.3-0.1-0.20.20.0-0.1-0.2
Indifference point function ln k1.32.46.32.52.41.61.41.31.51.41.41.9-2.01.21.21.3-1.9-1.11.11.10.4-1.1
Indifference point function log k1.32.46.32.52.41.61.41.31.51.41.41.9-2.01.21.21.3-1.9-1.11.11.10.4-1.1
Patch foraging total patch changes 0 sec0.71.31.7-0.9-0.9-1.2-1.1-1.2-1.3-1.3-1.3-1.01.0-1.1-1.1-1.01.11.1-1.1-1.2-1.20.9
Patch foraging total patch changes 12 sec5.57.19.7-3.0-3.1-2.9-2.6-2.5-2.9-2.8-2.8-2.83.0-2.4-2.4-2.52.92.3-2.3-2.6-2.12.2
Patch foraging total patch changes 18 sec0.30.51.2-0.9-1.1-0.7-0.7-0.7-0.9-0.9-0.9-0.80.9-0.4-0.5-0.60.70.6-0.6-0.6-0.40.4
Patch foraging total patch changes 24 sec5.08.510.0-3.0-3.1-3.2-2.6-2.9-3.2-3.1-3.1-3.02.9-2.8-2.8-3.02.92.8-2.8-2.7-2.62.8
Patch foraging total patch changes 6 sec1.42.22.9-1.4-1.5-1.7-1.3-1.4-1.7-1.6-1.6-1.41.4-1.4-1.4-1.51.41.4-1.4-1.4-1.41.4
Patch foraging time to switch 0 sec0.10.20.8-0.6-0.7-0.20.2-0.1-0.3-0.3-0.3-0.90.6-0.3-0.2-0.70.60.1-0.1-0.30.10.9
Patch foraging water rate 0 sec0.20.41.00.90.80.70.20.40.50.50.51.0-1.00.60.50.8-0.9-0.30.30.70.2-0.9
Patch foraging water rate 12 sec0.71.53.81.71.91.00.70.71.21.21.21.7-1.70.80.81.3-1.5-0.70.71.00.3-1.3
Patch foraging water rate 18 sec0.10.20.80.70.90.0-0.1-0.30.20.20.20.6-0.7-0.3-0.30.1-0.50.3-0.3-0.0-0.7-0.1
Patch foraging water rate 24 sec0.71.02.21.51.31.00.80.91.00.90.91.3-1.21.00.91.1-1.1-0.80.80.80.5-1.1
Patch foraging water rate 6 sec0.60.92.31.41.50.90.50.60.80.70.71.4-1.40.60.51.1-1.2-0.50.50.80.1-1.1
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.3-0.1-0.2-0.1-0.3-0.2-0.1-0.1-0.20.2-0.3-0.3-0.30.20.5-0.5-0.2-0.30.3
Distance traveled before self-admin1.41.93.5-1.8-1.9-1.6-1.0-1.2-1.4-1.4-1.4-1.61.4-1.3-1.3-1.51.21.2-1.2-1.2-0.81.5
Distance traveled after self-admin0.30.30.8-0.7-0.9-0.8-0.9-0.5-0.6-0.6-0.6-0.50.4-0.5-0.6-0.40.50.6-0.6-0.4-0.40.2
Extensor digitorum longus weight6.726.329.4-5.4-5.0-5.4-4.7-5.2-5.2-5.2-5.2-5.25.1-5.3-5.1-5.35.15.0-5.0-5.1-4.75.1
Bone: elastic displacement0.20.20.60.70.70.8-0.00.20.40.40.40.7-0.40.40.30.6-0.4-0.20.20.40.0-0.8
Bone: elastic work1.41.82.8-1.0-1.0-1.0-1.6-1.5-1.2-1.3-1.3-1.11.2-1.4-1.5-1.21.31.6-1.6-1.3-1.71.1
Bone: endosteal estimation1.02.15.71.31.51.02.41.61.61.61.60.9-1.61.31.60.8-1.6-1.61.61.31.6-0.2
Bone: endosteal perimeter1.94.19.31.71.81.23.02.32.12.12.11.4-2.12.02.31.4-2.2-2.32.31.92.5-0.8
Epididymis fat weight0.82.85.91.11.71.02.41.61.92.02.01.2-1.71.41.71.2-1.8-1.91.91.62.0-0.7
Delta time in closed arm before/after self-admin2.52.34.0-0.8-0.8-1.5-1.4-1.6-1.5-1.5-1.5-1.31.5-1.5-1.5-1.61.71.6-1.6-2.0-2.01.5
Delta time in open arm before/after self-admin1.01.02.6-1.4-1.6-0.8-0.7-0.7-1.0-1.0-1.0-1.31.2-0.8-0.8-1.00.90.8-0.8-0.6-0.30.9
Diff in mean of infusions in LGA sessions2.53.13.8-1.6-1.9-1.7-1.9-1.6-2.0-1.9-1.9-1.71.9-1.6-1.7-1.61.91.8-1.8-1.6-1.71.4
Delay discount exponential model param0.20.20.50.10.10.40.10.40.50.40.40.5-0.40.50.40.6-0.5-0.40.40.60.6-0.7
Extinction: sum of active levers before priming3.64.05.1-2.1-2.3-2.2-1.8-1.8-2.1-2.1-2.1-2.11.9-2.0-2.0-2.11.91.9-1.9-1.8-1.72.0
Active lever presses in extinction session 61.81.83.7-1.7-1.9-1.5-1.3-1.1-1.3-1.3-1.3-1.61.5-1.3-1.3-1.31.31.2-1.2-1.1-0.81.2
Bone: final force1.42.23.1-1.7-1.7-1.5-1.1-1.5-1.4-1.4-1.4-1.71.4-1.5-1.4-1.71.31.4-1.4-1.2-1.21.7
Bone: final moment1.42.33.2-1.8-1.7-1.6-1.2-1.5-1.5-1.5-1.5-1.71.5-1.6-1.5-1.71.31.5-1.5-1.2-1.21.8
Food consumed during 24 hour testing period0.20.20.5-0.00.4-0.00.30.20.50.50.50.5-0.70.40.30.6-0.7-0.30.30.50.5-0.6
Glucose1.93.04.61.92.01.42.11.71.81.91.91.7-1.91.61.71.4-1.8-1.81.81.51.5-1.1
Heart weight0.10.10.70.50.8-0.10.6-0.10.30.20.20.0-0.3-0.3-0.1-0.30.0-0.10.1-0.3-0.40.7
Delay discount hyperbolic model param0.10.10.40.00.00.3-0.00.30.30.20.20.3-0.30.30.30.5-0.4-0.30.30.50.4-0.6
Intermittent access intake day 1-15 change1.73.44.81.41.51.71.81.91.91.91.91.7-1.81.81.81.9-1.9-2.02.02.02.2-1.9
Intermittent access intake escalation2.14.35.91.61.61.91.92.12.12.12.11.9-2.02.12.02.2-2.1-2.22.22.32.4-2.1
Intermittent access intake escalation 21.31.42.80.70.70.81.21.31.31.31.31.0-1.11.21.21.2-1.3-1.31.31.31.7-1.2
Intermitt. access day 1 inactive lever presses0.52.02.61.31.21.41.41.61.41.41.41.3-1.21.51.51.5-1.3-1.61.61.41.6-1.5
Intermitt. access day 15 inactive lever presses0.10.31.0-0.8-0.8-0.70.2-0.3-0.2-0.2-0.2-1.00.5-0.5-0.3-0.80.30.4-0.4-0.30.21.0
Intermitt. access escalation Index0.40.60.90.91.00.80.60.60.70.70.70.9-0.90.70.70.8-0.8-0.70.70.70.4-0.8
Intermittent access day 1 total infusions0.50.73.80.90.71.12.00.90.90.90.9-0.1-0.60.50.8-0.1-0.5-0.80.80.60.80.8
Intermittent access day 15 total infusions4.16.210.42.32.22.73.22.72.72.72.71.8-2.52.32.52.0-2.4-2.52.52.62.8-1.5
Intermittent access terminal intake (last 3 days)1.82.36.51.31.11.62.51.81.71.71.70.7-1.41.31.60.8-1.4-1.61.61.62.0-0.2
Intermittent access total infusions1.61.95.51.41.21.72.41.71.51.51.50.6-1.31.11.40.6-1.1-1.41.41.41.6-0.0
Intermittent access day 1 locomotion0.20.21.50.50.30.71.20.50.30.30.3-0.4-0.10.10.3-0.4-0.1-0.40.40.10.30.9
Intermittent access day 15 total locomotion0.40.72.70.70.40.91.71.20.90.90.90.0-0.60.70.90.2-0.7-0.90.90.81.20.3
Intermittent access total locomotion0.81.04.90.80.41.02.21.31.01.01.0-0.2-0.70.71.0-0.1-0.7-0.90.90.81.40.8
Intermittent access standard deviation0.81.72.31.21.21.21.41.51.51.51.51.1-1.31.21.31.2-1.2-1.31.31.31.5-1.1
Left kidney weight0.10.62.10.60.70.41.40.80.80.80.80.3-0.70.50.80.3-0.6-0.90.90.60.90.1
Right kidney weight0.10.31.10.30.50.11.00.60.60.70.70.2-0.50.30.50.2-0.4-0.70.70.40.80.0
Cocaine induced anxiety0.00.00.1-0.1-0.1-0.0-0.10.10.10.10.1-0.10.20.10.10.10.0-0.10.10.00.3-0.2
Post-drug Anxiety0.20.20.4-0.6-0.6-0.6-0.5-0.4-0.4-0.4-0.4-0.50.6-0.4-0.4-0.40.40.6-0.6-0.5-0.20.4
Baseline Anxiety0.70.81.4-0.6-0.6-0.9-0.9-0.9-0.9-0.9-0.9-0.70.7-0.9-0.9-0.90.81.0-1.0-0.9-1.20.9
Tail length0.41.72.9-1.4-1.0-1.1-1.7-1.6-1.5-1.6-1.6-0.91.2-1.3-1.4-0.91.31.2-1.2-1.1-1.50.6
Length with tail1.56.58.2-2.9-2.5-2.8-2.7-2.8-2.8-2.8-2.8-2.32.4-2.6-2.6-2.32.32.4-2.4-2.3-2.42.0
Length without tail3.210.414.2-3.3-3.2-3.8-3.2-3.3-3.5-3.3-3.3-3.03.0-3.3-3.3-3.13.03.2-3.2-3.2-3.12.9
Times rat made contact with spout0.30.40.9-0.4-0.2-0.4-0.9-0.8-0.7-0.7-0.7-0.20.3-0.6-0.7-0.30.50.7-0.7-0.4-0.80.1
Lifetime Intake1.11.33.91.31.11.52.01.41.31.31.30.5-1.00.91.10.4-0.9-1.11.11.11.10.1
Liver weight, left1.01.62.31.31.51.01.11.11.31.41.41.4-1.41.21.21.4-1.3-1.31.31.11.1-1.4
Liver weight, right0.91.53.01.51.71.01.30.91.21.21.21.4-1.61.01.01.1-1.5-1.11.11.10.7-0.9
Locomotor activity0.30.41.91.11.40.50.00.20.60.50.51.0-0.80.30.20.7-0.6-0.20.20.3-0.2-0.8
Locomotor testing distance0.30.51.91.31.40.80.20.10.70.60.61.0-0.90.30.20.7-0.8-0.20.20.4-0.3-0.7
Locomotor testing rearing0.40.82.11.21.50.90.40.41.01.01.01.2-1.20.60.50.9-1.2-0.60.60.80.1-0.9
Locomotion in novel chamber2.32.94.11.71.71.82.01.91.91.91.91.4-1.71.61.71.5-1.7-1.71.71.71.8-1.2
Locomotion in novel chamber post-restriction2.03.34.41.91.71.91.92.11.61.71.71.7-1.62.02.01.8-1.4-1.91.91.82.0-1.7
Fecal boli incidents, locomotor time 10.60.91.80.40.40.81.01.00.91.01.00.6-0.81.01.00.8-1.0-1.01.01.11.3-0.8
Change in fecal boli incidents, locomotor task0.40.41.51.21.20.70.70.50.50.50.50.9-0.70.60.50.6-0.5-0.50.50.30.1-0.5
Time >=10cm from walls, locomotor time 13.13.35.71.41.31.72.42.11.71.81.81.3-1.72.02.11.5-1.8-2.02.01.92.3-1.2
Bouts of movement, locomotor time 10.10.10.6-0.3-0.50.0-0.80.1-0.2-0.1-0.10.10.40.30.10.30.30.1-0.1-0.00.2-0.8
Total resting periods, locomotor time 10.10.10.4-0.3-0.5-0.0-0.60.1-0.1-0.0-0.00.00.30.30.10.30.20.0-0.00.00.3-0.7
Rest time, locomotor task time 11.82.32.91.31.51.51.31.41.51.51.51.6-1.51.41.41.7-1.5-1.61.61.61.5-1.7
Distance moved, locomotor task time 10.30.40.8-0.6-0.6-0.8-0.4-0.6-0.5-0.6-0.6-0.80.6-0.7-0.6-0.80.50.7-0.7-0.7-0.70.9
Vertical activity count, locomotor time 10.20.40.70.80.70.60.70.60.60.60.60.6-0.60.60.60.5-0.8-0.50.50.50.4-0.4
Time >=10cm from walls, locomotor time 20.30.41.10.10.10.40.60.80.60.70.70.4-0.50.80.80.7-0.6-0.70.70.81.1-0.7
Bouts of movement, locomotor time 20.81.21.7-1.3-1.2-1.1-1.3-1.1-1.0-1.1-1.1-1.11.1-1.1-1.1-1.01.11.1-1.1-0.9-0.90.8
Total resting periods, locomotor time 20.30.50.8-0.9-0.8-0.7-0.8-0.7-0.6-0.7-0.7-0.70.7-0.7-0.7-0.60.70.7-0.7-0.6-0.50.5
Rest time, locomotor task time 22.83.64.22.02.12.01.91.91.71.91.91.9-1.91.91.91.9-1.8-1.91.91.81.7-1.8
Distance moved, locomotor task time 20.40.51.1-0.8-0.8-0.8-1.1-0.8-0.5-0.6-0.6-0.60.7-0.7-0.8-0.50.70.8-0.8-0.7-0.60.3
Vertical activity count, locomotor time 20.10.10.50.10.0-0.1-0.7-0.3-0.1-0.3-0.30.20.1-0.1-0.30.20.10.3-0.3-0.2-0.5-0.4
Light reinforcement 10.00.10.30.10.20.2-0.1-0.00.30.20.20.4-0.50.20.10.4-0.5-0.20.20.60.2-0.5
Light reinforcement 20.60.92.30.10.30.81.31.01.00.90.90.4-0.71.01.10.6-0.8-1.21.21.31.5-0.5
Bone: marrow area1.22.56.31.51.61.12.51.71.71.71.71.1-1.71.51.71.0-1.7-1.71.71.41.7-0.4
Bone: maximum diameter0.10.10.4-0.5-0.5-0.60.50.1-0.1-0.1-0.1-0.50.1-0.10.1-0.30.1-0.20.2-0.20.50.5
Bone: maximum force1.93.35.9-2.3-2.1-2.2-1.1-1.7-1.6-1.6-1.6-2.31.8-1.9-1.7-2.21.61.6-1.6-1.6-1.32.4
Bone: maximum moment2.03.55.8-2.3-2.1-2.2-1.1-1.8-1.6-1.6-1.6-2.31.8-2.0-1.7-2.21.61.7-1.7-1.6-1.32.4
Mean time between licks in bursts0.61.43.1-0.6-0.4-1.1-1.5-1.6-0.8-0.8-0.8-0.70.7-1.5-1.5-1.00.91.6-1.6-1.2-1.70.9
Mean num. licks in bursts0.00.00.10.30.10.3-0.2-0.00.20.20.20.2-0.10.10.00.2-0.00.0-0.0-0.0-0.1-0.3
Cd content in liver1.11.22.11.10.81.01.41.40.80.80.80.9-0.91.41.41.0-1.0-1.21.21.01.3-0.9
Co content in liver0.50.51.41.10.90.9-0.00.50.50.50.51.1-0.80.70.51.0-0.8-0.40.40.60.1-1.2
Cu content in liver0.00.00.10.20.10.2-0.20.1-0.00.00.00.10.0-0.0-0.00.10.10.1-0.1-0.0-0.1-0.2
Fe content in liver0.00.00.10.30.10.10.20.3-0.0-0.0-0.00.0-0.00.20.2-0.00.0-0.10.1-0.00.00.1
K content in liver0.50.50.9-0.9-0.6-0.7-0.5-0.9-0.6-0.6-0.6-0.70.5-0.9-0.8-0.80.40.6-0.6-0.3-0.70.8
Mg content in liver0.20.20.4-0.1-0.0-0.3-0.1-0.5-0.5-0.5-0.5-0.30.2-0.5-0.4-0.50.20.3-0.3-0.2-0.60.6
Mn content in liver2.62.94.5-2.1-2.0-1.8-1.6-1.7-1.8-1.7-1.7-1.91.8-1.7-1.7-1.71.71.6-1.6-1.2-1.31.6
Na content in liver0.30.30.7-0.8-0.7-0.7-0.4-0.7-0.5-0.5-0.5-0.60.4-0.7-0.6-0.60.20.4-0.4-0.2-0.40.6
Rb content in liver1.72.03.61.71.91.41.31.21.41.31.31.7-1.61.31.31.5-1.5-1.41.41.20.9-1.4
Se content in liver0.00.00.2-0.4-0.3-0.00.30.10.00.00.0-0.30.10.00.1-0.10.1-0.20.20.20.40.2
Sr content in liver4.13.64.4-2.0-2.0-1.9-1.8-1.8-2.1-2.1-2.1-2.02.1-1.7-1.8-1.82.11.8-1.8-1.9-1.51.6
Zn content in liver3.03.44.3-1.6-1.9-1.9-1.5-1.6-2.1-2.1-2.1-1.92.0-1.7-1.6-1.92.01.7-1.7-2.0-1.61.8
Bone: minimum diameter0.61.23.50.81.00.51.91.11.21.21.20.6-1.20.91.20.5-1.3-1.21.21.01.4-0.0
Time in familiar zone, hab. session 10.10.10.2-0.2-0.3-0.3-0.2-0.3-0.1-0.2-0.2-0.3-0.1-0.4-0.3-0.4-0.10.4-0.4-0.1-0.30.4
Time in novel zone, hab. session 11.11.11.81.21.41.30.70.81.01.21.21.3-1.10.90.81.2-1.1-0.90.91.20.6-1.2
Total zone transitions, hab. session 10.30.41.1-0.5-0.5-0.7-0.6-0.4-1.0-1.0-1.0-0.60.7-0.5-0.6-0.50.70.5-0.5-0.7-0.60.5
Total locomotion distance, hab. session 10.10.10.60.40.10.10.80.6-0.1-0.1-0.1-0.0-0.00.40.50.0-0.0-0.50.50.10.40.2
Locomotion velocity, hab. session 10.10.20.5-0.3-0.5-0.40.20.0-0.7-0.7-0.7-0.60.6-0.1-0.0-0.50.60.0-0.0-0.4-0.00.6
Time in familiar zone, hab. session 20.30.40.90.30.60.8-0.4-0.10.70.50.50.8-0.90.0-0.00.7-1.00.1-0.10.9-0.1-0.9
Time in novel zone, hab. session 20.60.61.3-0.6-0.7-1.0-0.2-0.4-0.8-0.7-0.7-1.01.0-0.6-0.5-1.01.00.5-0.5-1.1-0.51.1
Total zone transitions, hab. session 21.82.33.1-1.2-1.5-1.5-1.3-1.5-1.6-1.7-1.7-1.41.3-1.6-1.6-1.61.21.6-1.6-1.5-1.61.6
Total locomotion distance, hab. session 20.20.30.7-0.3-0.5-0.5-0.1-0.4-0.7-0.8-0.8-0.60.5-0.5-0.4-0.70.40.5-0.5-0.5-0.50.8
Locomotion velocity, hab. session 20.10.10.5-0.1-0.4-0.40.2-0.1-0.5-0.6-0.6-0.50.3-0.3-0.1-0.50.30.2-0.2-0.4-0.20.7
Novel to familiar place preference ratio1.71.93.2-1.6-1.5-1.8-1.0-1.1-1.2-1.3-1.3-1.61.7-1.2-1.1-1.41.71.0-1.0-1.6-0.81.4
Novelty place preference1.01.02.1-1.3-1.1-1.4-0.7-0.8-0.9-0.9-0.9-1.21.3-0.9-0.8-1.11.40.7-0.7-1.3-0.51.1
Time in novel zone, NPP test1.11.22.2-1.3-1.1-1.5-0.8-0.9-0.9-0.9-0.9-1.31.4-1.0-0.9-1.21.40.8-0.8-1.3-0.71.2
Total zone transitions, NPP test1.52.13.3-1.1-1.5-1.3-1.2-1.3-1.7-1.8-1.8-1.41.5-1.3-1.3-1.41.41.4-1.4-1.7-1.41.4
Total locomotion distance, NPP test0.20.30.70.0-0.4-0.3-0.1-0.2-0.7-0.7-0.7-0.50.6-0.4-0.3-0.60.60.4-0.4-0.9-0.50.7
Locomotion velocity, NPP test0.10.20.50.1-0.4-0.2-0.0-0.0-0.6-0.6-0.6-0.30.5-0.1-0.1-0.40.50.2-0.2-0.7-0.30.4
Intraocular pressure0.20.20.70.30.40.60.10.50.50.40.40.6-0.40.50.40.7-0.5-0.40.40.50.5-0.8
Delta distance traveled before/after self-admin0.20.20.70.80.70.4-0.20.30.30.30.30.7-0.60.30.10.5-0.4-0.10.10.4-0.2-0.7
Delta ambulatory time before/after self-admin0.30.41.01.01.00.70.00.50.50.50.51.0-0.80.50.40.8-0.6-0.30.30.60.0-1.0
Parametrial fat weight1.74.08.91.71.91.23.02.22.12.02.01.5-2.02.02.21.5-1.9-2.42.41.72.4-1.0
Pavlov. Cond. lever latency0.81.01.61.21.21.00.61.00.91.01.01.2-0.81.00.91.2-0.8-0.90.90.70.7-1.3
Pavlov. Cond. magazine entry latency0.50.61.7-1.3-1.3-0.8-0.3-0.7-0.5-0.5-0.5-1.20.7-0.7-0.6-1.00.60.7-0.7-0.3-0.21.1
Pavlov. Cond. change in total contacts0.10.10.8-0.7-0.9-0.20.30.0-0.2-0.2-0.2-0.60.20.00.1-0.40.2-0.00.00.20.50.4
Pavlov. Cond. index score0.30.41.2-1.1-1.1-0.6-0.4-0.6-0.5-0.5-0.5-0.90.5-0.6-0.5-0.80.50.6-0.6-0.2-0.20.8
Pavlov. Cond. latency score0.30.41.0-1.0-1.0-0.7-0.4-0.7-0.5-0.5-0.5-0.90.5-0.7-0.6-0.80.40.6-0.6-0.3-0.40.9
Pavlov. Cond. lever contacts0.30.40.9-0.8-0.8-0.6-0.3-0.7-0.5-0.6-0.6-0.80.5-0.7-0.6-0.80.40.6-0.6-0.3-0.40.9
Pavlov. Cond. magazine entry number0.30.41.61.11.30.60.50.60.50.50.50.9-0.60.50.50.7-0.6-0.60.60.20.1-0.6
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.1-0.10.3-0.00.30.30.30.3-0.00.20.30.30.30.2-0.30.30.00.5-0.4
Pavlov. Cond. lever-magazine prob. diff.0.40.41.3-1.1-1.1-0.6-0.4-0.6-0.5-0.6-0.6-0.90.6-0.5-0.5-0.80.50.5-0.5-0.2-0.10.8
Pavlov. Cond. response bias0.50.61.7-1.3-1.3-0.7-0.5-0.7-0.6-0.6-0.6-1.00.7-0.7-0.6-0.90.60.6-0.6-0.3-0.20.9
Pavlov. Cond. lever latency0.30.51.31.00.81.20.60.70.40.40.40.8-0.40.80.70.7-0.3-0.70.70.70.4-0.8
Pavlov. Cond. magazine entry latency4.04.87.6-2.7-2.8-2.3-2.3-2.2-1.9-1.9-1.9-2.42.2-2.2-2.2-2.22.02.2-2.2-1.9-1.82.0
Pavlov. Cond. change in total contacts0.61.02.6-1.6-1.5-1.6-0.8-0.9-0.7-0.7-0.7-1.20.8-1.0-0.9-1.00.50.8-0.8-0.8-0.41.0
Pavlov. Cond. index score1.72.34.4-2.1-2.1-1.9-1.4-1.5-1.1-1.1-1.1-1.81.4-1.5-1.4-1.61.21.5-1.5-1.3-0.91.5
Pavlov. Cond. latency score1.52.04.0-2.0-2.0-1.8-1.2-1.3-1.1-1.1-1.1-1.71.3-1.4-1.3-1.61.11.3-1.3-1.2-0.81.5
Pavlov. Cond. lever contacts0.20.31.0-0.9-0.8-1.0-0.6-0.6-0.2-0.2-0.2-0.60.3-0.6-0.6-0.60.20.6-0.6-0.5-0.30.5
Pavlov. Cond. magazine entry number5.97.311.43.33.43.02.72.62.42.42.43.0-2.82.72.62.8-2.5-2.62.62.52.1-2.5
Pavlov. Cond. intertrial magazine entries1.62.43.11.61.51.61.51.71.21.21.21.6-1.41.71.71.6-1.4-1.81.81.51.5-1.6
Pavlov. Cond. lever-magazine prob. diff.2.02.65.0-2.2-2.2-2.0-1.5-1.6-1.2-1.2-1.2-1.91.5-1.7-1.6-1.71.31.6-1.6-1.4-1.11.6
Pavlov. Cond. response bias1.52.13.7-1.9-1.7-1.9-1.4-1.5-1.1-1.1-1.1-1.61.2-1.6-1.5-1.51.11.5-1.5-1.3-1.11.4
Time in closed arm before self-admin0.20.30.7-0.00.20.40.70.50.60.60.60.2-0.70.40.50.4-0.7-0.60.60.80.9-0.3
Time in closed arm after self-admin0.60.61.40.81.20.80.70.50.90.90.90.9-1.00.70.70.7-0.8-0.70.70.60.5-0.6
Time in open arm before self-admin0.20.21.41.21.00.5-0.10.10.10.10.10.8-0.30.10.00.4-0.20.0-0.0-0.1-0.7-0.4
Time in open arm after self-admin0.70.71.2-0.4-0.8-0.5-1.0-0.6-1.1-1.1-1.1-0.71.0-0.8-0.9-0.70.90.9-0.9-0.8-1.00.6
Bone: periosteal estimation0.10.21.2-0.10.1-0.21.10.40.40.40.4-0.2-0.40.20.4-0.2-0.5-0.50.50.40.70.6
Bone: periosteal perimeter0.10.20.7-0.10.0-0.30.90.40.30.30.3-0.1-0.40.20.40.0-0.5-0.50.50.40.80.2
Bone: post-yield work0.30.52.50.20.1-0.11.60.80.70.70.7-0.2-0.60.50.8-0.1-0.7-0.70.70.51.10.6
Progressive ratio test 1 active lever presses0.50.71.81.00.71.31.11.10.80.80.80.4-0.60.80.80.4-0.5-0.80.80.90.8-0.2
Progressive ratio test 1 breakpoint0.60.71.81.00.61.31.11.10.80.80.80.4-0.60.80.90.4-0.5-0.80.80.90.9-0.2
Progressive ratio test 1 inactive lever presses0.40.51.2-0.7-0.8-0.4-0.4-0.6-0.6-0.6-0.6-1.00.8-0.7-0.6-1.01.00.6-0.6-0.4-0.51.1
Progressive ratio test 2 active lever presses1.51.83.61.31.01.61.91.71.41.41.40.7-1.21.21.40.9-1.0-1.41.41.51.7-0.5
Progressive ratio test 2 breakpoint1.41.63.41.20.91.51.81.61.41.41.40.6-1.11.21.30.8-1.0-1.31.31.41.6-0.4
Progressive ratio test 2 inactive lever presses0.81.33.30.90.81.21.81.41.31.31.30.5-1.01.01.20.7-0.9-1.21.21.21.6-0.3
Incentive Sensitization - Responses0.20.31.1-0.7-0.8-0.70.1-0.3-0.3-0.3-0.3-1.00.5-0.6-0.4-0.80.60.4-0.4-0.4-0.01.1
Incentive Sensitization - Breakpoint0.20.20.9-0.6-0.6-0.60.3-0.2-0.2-0.2-0.2-0.80.3-0.4-0.3-0.70.40.2-0.2-0.30.10.9
Sum of active levers in priming session hrs 5-60.20.21.3-1.0-1.1-0.6-0.5-0.0-0.3-0.3-0.3-0.50.60.1-0.0-0.10.40.1-0.10.00.5-0.2
Progressive ratio0.00.10.4-0.1-0.00.10.60.20.30.10.1-0.1-0.30.00.2-0.1-0.3-0.10.10.30.40.4
Food seeking constrained by brief footshock0.00.00.10.20.10.10.10.00.0-0.0-0.00.1-0.20.00.00.0-0.10.0-0.00.0-0.1-0.0
Seeking ratio, punishment vs. effort0.10.10.60.20.1-0.2-0.5-0.4-0.4-0.3-0.30.00.3-0.2-0.3-0.10.50.3-0.3-0.5-0.80.0
Retroperitoneal fat weight3.314.119.83.94.33.34.53.84.03.93.93.6-3.93.73.83.4-3.8-3.93.93.23.5-2.8
Reaction time number correct0.50.91.7-1.0-0.6-1.1-1.3-1.3-0.7-0.7-0.7-0.60.5-1.2-1.3-0.70.51.1-1.1-0.7-1.20.6
Reaction time mean minus median0.10.20.7-0.8-0.8-0.7-0.20.1-0.2-0.2-0.2-0.50.50.10.1-0.00.5-0.10.1-0.30.6-0.1
Reaction time mean minus median AUC0.00.10.3-0.4-0.4-0.3-0.40.10.00.00.00.00.10.20.20.30.2-0.10.1-0.00.5-0.6
Reaction time num false alarms0.10.10.70.90.60.4-0.40.00.0-0.0-0.00.5-0.10.1-0.10.2-0.00.1-0.1-0.2-0.7-0.3
Reaction time num false alarms AUC0.20.31.40.30.1-0.2-1.0-0.5-0.6-0.6-0.6-0.00.5-0.5-0.6-0.20.60.7-0.7-0.8-1.20.1
Reaction time trials correct on left0.50.91.7-1.0-0.6-1.1-1.3-1.3-0.7-0.7-0.7-0.60.5-1.2-1.3-0.70.51.1-1.1-0.7-1.20.6
Reaction time trials on left0.50.91.9-1.0-0.6-1.1-1.4-1.3-0.7-0.8-0.8-0.60.6-1.2-1.3-0.80.61.1-1.1-0.7-1.20.6
Reaction time mean0.20.40.90.2-0.10.50.40.90.60.60.60.3-0.40.70.70.6-0.7-0.60.60.61.0-0.7
Reaction time mean AUC0.40.61.20.30.10.60.61.00.80.80.80.5-0.70.80.80.8-0.9-0.70.70.81.1-0.8
Median of all reaction times0.20.20.60.2-0.20.50.40.80.40.50.50.2-0.40.50.50.4-0.7-0.40.40.50.7-0.4
Reaction time omissions0.10.20.6-0.6-0.8-0.6-0.8-0.3-0.5-0.5-0.5-0.40.6-0.2-0.3-0.20.60.4-0.4-0.5-0.2-0.0
Reaction time false alarm rate0.10.10.80.90.50.5-0.00.3-0.0-0.0-0.00.30.10.30.20.20.1-0.10.1-0.3-0.3-0.2
Reaction time premature initiation rate5.57.510.4-2.6-2.4-2.8-2.7-3.2-2.7-2.6-2.6-2.62.4-3.1-3.0-2.92.52.8-2.8-2.6-3.02.8
Reaction time premature initiations5.39.513.9-3.0-2.6-3.2-3.4-3.7-2.9-2.9-2.9-2.72.6-3.5-3.5-3.02.73.3-3.3-2.8-3.52.8
Std. dev. reaction times0.20.41.20.3-0.00.40.31.00.50.50.50.5-0.30.90.80.8-0.4-0.70.70.51.1-1.0
Reaction time trials completed0.50.91.9-1.0-0.6-1.1-1.4-1.3-0.7-0.8-0.8-0.60.6-1.2-1.3-0.80.61.1-1.1-0.7-1.20.6
Reaction time trials AUC0.40.81.6-0.9-0.5-1.0-1.2-1.2-0.6-0.7-0.7-0.50.5-1.2-1.2-0.70.51.1-1.1-0.6-1.20.5
Run reversals in cocaine runway, females1.21.22.2-0.5-0.6-0.8-0.6-1.0-1.1-1.1-1.1-1.00.9-1.2-1.1-1.31.01.1-1.1-1.3-1.51.5
Run reversals in cocaine runway, males0.40.40.60.70.70.70.40.60.30.50.50.8-0.60.70.60.8-0.5-0.70.70.60.5-0.8
Latency to leave start box in cocaine runway0.30.41.00.60.80.41.00.60.80.70.70.4-0.70.40.50.3-0.7-0.60.60.40.6-0.1
Latency to leave start box in cocaine runway, F0.00.10.2-0.2-0.0-0.4-0.0-0.3-0.1-0.0-0.0-0.30.2-0.3-0.3-0.30.20.2-0.2-0.3-0.20.4
Latency to leave start box in cocaine runway, M2.01.92.51.51.51.31.61.41.51.41.41.3-1.51.21.31.2-1.5-1.21.21.31.3-1.0
Std. dev. time between licks in bursts0.10.10.60.20.4-0.1-0.5-0.60.10.10.10.2-0.2-0.5-0.5-0.0-0.20.6-0.6-0.2-0.70.0
Total sessions with >9 infusions0.81.02.01.21.11.41.31.11.11.11.10.7-0.90.91.00.7-0.8-1.01.01.10.8-0.4
Short access day 1 total inactive lever presses0.10.10.30.50.20.50.50.40.10.10.1-0.2-0.10.00.1-0.3-0.0-0.00.00.1-0.00.5
Short access day 10 total inactive lever presses0.20.50.90.90.80.50.60.80.70.70.70.9-0.70.80.80.8-0.8-0.80.80.50.6-0.8
Short access day 1 total infusions1.21.63.11.51.41.81.61.31.31.31.31.0-1.21.11.20.9-1.1-1.21.21.31.0-0.5
Short access day 10 total infusions0.40.52.10.70.61.01.40.80.70.70.7-0.0-0.50.40.6-0.1-0.4-0.60.60.60.60.6
Short access total infusions0.50.62.01.11.01.21.40.90.80.80.80.3-0.70.60.70.2-0.5-0.70.70.70.50.3
Short access day 1 locomotion0.40.51.50.80.61.21.00.80.70.70.70.3-0.60.50.60.3-0.5-0.60.60.90.6-0.0
Short access day 10 total locomotion0.10.10.70.1-0.10.20.80.3-0.0-0.0-0.0-0.50.1-0.10.1-0.50.0-0.20.20.00.20.9
Short access total locomotion0.20.31.30.60.40.71.10.80.50.50.5-0.1-0.30.40.5-0.0-0.4-0.50.50.50.60.4
One hour access (0.3 mA shock)1.41.73.91.31.11.52.01.61.41.41.40.8-1.11.11.30.8-1.2-1.41.41.21.5-0.4
Compulsive drug intake1.31.63.5-1.1-0.9-1.4-1.9-1.5-1.3-1.3-1.3-0.71.0-1.3-1.4-0.81.01.3-1.3-1.3-1.60.5
One hour access (shock baseline)3.65.610.12.32.02.73.22.72.52.52.51.7-2.12.22.41.8-2.2-2.52.52.42.7-1.3
Social response proportion0.10.10.3-0.5-0.0-0.6-0.3-0.60.00.00.0-0.10.1-0.4-0.3-0.20.20.2-0.2-0.3-0.30.1
Social responses0.10.10.6-0.4-0.1-0.5-0.7-0.6-0.2-0.3-0.30.00.1-0.3-0.40.00.20.3-0.3-0.2-0.4-0.3
Social time0.10.10.3-0.00.2-0.5-0.5-0.2-0.3-0.3-0.30.20.1-0.1-0.20.20.20.1-0.1-0.4-0.3-0.4
Soleus weight2.77.99.93.13.22.92.72.82.82.72.73.0-3.02.82.82.8-3.0-2.72.72.72.4-2.7
Bone: stiffness0.30.41.5-1.2-1.0-0.9-0.3-0.5-0.5-0.5-0.5-0.90.6-0.6-0.5-0.80.40.4-0.4-0.2-0.10.8
Tibialis anterior weight8.829.934.9-5.9-5.8-5.6-5.1-5.2-5.8-5.8-5.8-5.65.9-5.3-5.3-5.45.95.1-5.1-5.5-4.75.0
Time to tail flick, vehicle, before self-admin0.10.10.7-0.3-0.3-0.20.3-0.1-0.2-0.2-0.2-0.60.4-0.2-0.1-0.60.40.2-0.2-0.3-0.00.8
Time to tail flick, vehicle, after self-admin0.40.51.1-0.5-0.4-0.6-0.4-0.7-0.7-0.8-0.8-0.80.6-0.8-0.7-0.90.70.7-0.7-0.7-0.81.0
Time to tail flick, test, before self-admin0.70.72.2-0.3-0.4-0.6-0.2-0.7-0.9-0.9-0.9-0.90.8-1.0-0.8-1.20.70.8-0.8-1.0-1.01.5
Time to tail flick, test, after self-admin0.00.00.1-0.3-0.1-0.10.10.10.10.20.2-0.0-0.00.10.10.1-0.1-0.10.10.00.3-0.1
Delta time to tail flick, vehicle, before/after SA0.40.40.6-0.5-0.5-0.6-0.6-0.7-0.7-0.7-0.7-0.50.5-0.6-0.6-0.60.50.6-0.6-0.7-0.80.5
Delta time to tail flick, test, before/after SA0.30.31.3-0.2-0.10.2-0.20.40.50.50.50.5-0.30.60.50.8-0.4-0.50.50.60.8-1.1
Tibia length0.82.25.8-2.1-2.4-1.7-0.8-1.0-1.7-1.7-1.7-1.91.8-1.2-1.0-1.51.60.9-0.9-1.1-0.41.5
Ambulatory time before self-admin0.91.33.0-1.6-1.7-1.4-0.9-0.9-1.1-1.1-1.1-1.41.1-1.1-1.0-1.20.91.0-1.0-0.9-0.51.1
Ambulatory time after self-admin0.10.10.3-0.4-0.5-0.5-0.3-0.1-0.2-0.2-0.2-0.30.0-0.2-0.2-0.20.00.2-0.2-0.00.10.2
Bone: tissue strength0.30.30.80.30.60.20.20.00.60.60.60.7-0.80.20.20.6-0.9-0.30.30.70.2-0.6
Total heroin consumption5.56.48.4-2.7-2.9-2.8-2.9-2.4-2.7-2.7-2.7-2.42.7-2.3-2.4-2.22.72.5-2.5-2.4-2.21.8
Bone: trabecular number0.91.52.9-1.3-1.3-1.2-0.7-1.1-1.2-1.1-1.1-1.51.2-1.3-1.2-1.51.11.2-1.2-1.0-1.01.7
Bone: trabecular spacing0.40.51.30.70.90.80.00.30.80.80.81.0-0.80.50.40.9-0.8-0.50.50.70.2-1.1
Bone: trabecular thickness0.30.40.70.40.40.70.70.80.60.60.60.4-0.60.70.70.5-0.7-0.60.60.90.8-0.4
Bone: trabecular tissue density4.97.39.23.02.52.92.32.82.52.42.42.9-2.62.92.82.9-2.6-2.72.72.62.4-2.9
Water consumed over 24 hours0.70.91.7-1.1-0.7-1.0-1.3-1.3-1.0-1.0-1.0-0.70.7-1.1-1.1-0.70.71.1-1.1-0.7-1.10.5
Number of responses in last shaping day0.30.30.6-0.3-0.3-0.2-0.6-0.5-0.6-0.6-0.6-0.50.6-0.6-0.6-0.60.70.5-0.5-0.6-0.80.6