Hub : Genes

LOC102555623

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression LOC102555623 0.38 0.1 0.0e+00 0.3 0.33 0.34 0.25 3.8e-34 7.0e-38 1.4e-38 1.1e-27
2 OFC alternative TSS XR_005501334.1 0.23 0.12 5.1e-03 0.06 0.06 0.01 0.03 1.8e-02 1.5e-02 1.5e-01 8.7e-02
3 Liver alternative TSS XR_591363.2 0.08 0.04 1.8e-07 0.05 0.05 0.05 0.03 3.1e-06 1.1e-06 1.2e-06 1.5e-04
4 Adipose alternative TSS XR_005501334.1 0.04 0.02 1.4e-03 0.01 0.02 0.01 0 8.6e-03 3.2e-03 1.1e-02 1.2e-01
5 Liver alternative TSS XR_005501334.1 0.19 0.08 0.0e+00 0.14 0.15 0.13 0.14 9.2e-15 7.2e-16 2.0e-14 1.2e-15
6 Liver alternative TSS XR_005501334.1 0.22 0.09 0.0e+00 0.15 0.18 0.17 0.17 1.6e-16 5.0e-20 5.7e-19 6.1e-19
7 Adipose alternative TSS XR_005501334.1 0.05 0.03 5.5e-05 0.02 0.03 0.03 0.01 1.1e-03 1.7e-04 7.2e-04 4.4e-02
8 Adipose alternative TSS XR_352069.3 0.05 0.03 1.5e-04 0.03 0.03 0.02 0.01 7.9e-04 4.9e-04 6.5e-03 1.9e-02
9 PL gene expression LOC102555623 0.04 0.02 1.3e-04 0.02 0.02 0.02 0.02 2.2e-03 2.9e-03 2.0e-03 2.3e-03
10 Liver alternative TSS XR_005501333.1 0.03 0.02 9.4e-03 0.02 0.01 0.01 0.01 1.8e-03 2.8e-02 1.3e-02 8.7e-03
11 Adipose alternative TSS XR_352069.3 0.05 0.03 9.3e-05 0.03 0.03 0.02 0.01 2.6e-04 3.7e-04 2.5e-03 1.1e-02
12 NAcc gene expression LOC102555623 0.05 0.02 1.2e-05 0.04 0.03 0.03 0.04 3.2e-05 6.9e-05 1.0e-04 4.6e-05
13 Liver isoform ratio XR_005501334.1 0.2 0.08 0.0e+00 0.15 0.15 0.15 0.15 2.9e-16 2.7e-16 1.7e-16 2.4e-16
14 Adipose gene expression LOC102555623 0.17 0.07 5.6e-17 0.1 0.13 0.12 0.14 9.3e-11 2.6e-14 1.3e-13 3.1e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.40.73.10.70.1-0.80.50.80.80.4-0.61.80.90.81.2-0.80.1
Area under the delay curve0.20.20.70.20.9-0.30.60.40.30.6-0.6-0.20.40.60.1-0.3-0.4
BMI with tail3.09.614.0-3.7-3.13.4-3.6-3.3-3.4-3.73.5-2.3-2.9-2.8-0.82.82.9
BMI without tail3.36.810.8-2.8-3.32.5-3.0-2.7-2.6-2.92.9-2.1-2.7-2.7-1.62.21.9
Body weight3.916.323.1-4.8-4.44.1-4.5-4.3-4.3-4.54.5-3.0-4.2-3.9-2.23.83.3
Weight adjusted by age0.00.00.3-0.00.50.10.2-0.0-0.10.2-0.1-0.20.1-0.20.0-0.10.0
Bone surface0.10.21.5-0.1-0.5-0.40.10.30.30.1-0.21.20.20.40.8-0.50.3
Bone volume0.20.31.70.2-0.7-0.60.20.40.50.2-0.21.30.30.30.6-0.50.2
Breakpoint value in progressive ratio session0.60.71.4-0.80.31.2-1.2-0.8-1.0-1.20.90.3-0.4-0.50.60.51.2
Number of licking bursts1.51.73.7-1.60.21.9-1.6-1.4-1.6-1.51.2-1.5-0.8-0.8-1.01.40.5
Context. condit. distance diff. score0.10.21.50.11.20.3-0.10.1-0.0-0.0-0.2-0.10.50.60.2-0.2-0.4
Locomotion velocity, session 11.61.83.9-1.3-0.71.4-1.0-1.5-1.4-1.01.2-1.8-1.5-1.6-2.00.90.5
Locomotion distance, session 11.92.48.0-1.70.22.0-1.3-1.7-1.7-1.21.3-2.8-1.3-1.4-2.10.90.3
Locomotion velocity, session 20.10.10.3-0.30.20.5-0.3-0.4-0.5-0.30.3-0.3-0.3-0.4-0.3-0.30.3
Locomotion distance, session 21.52.19.1-1.30.71.6-0.7-1.4-1.4-0.60.9-3.0-1.2-1.5-2.50.9-0.1
Locomotion velocity, session 31.31.55.8-1.1-0.31.2-0.8-1.2-1.1-0.70.8-2.0-1.0-1.0-2.41.3-0.4
Locomotion distance, session 30.20.20.7-0.40.60.5-0.2-0.3-0.3-0.10.0-0.80.0-0.0-0.70.4-0.4
Stereotopy head waving bouts, day 30.70.82.8-0.7-0.90.7-0.6-0.9-0.7-0.60.8-1.0-1.1-1.2-1.71.10.1
Stereotopy head waving duration, day 31.31.63.0-1.2-1.31.2-1.2-1.3-1.2-1.21.3-1.2-1.4-1.4-1.71.10.5
Locomotion velocity, session 71.41.52.6-1.4-0.21.5-1.2-1.4-1.4-1.21.2-1.6-1.1-1.1-1.11.20.8
Locomotion distance, session 70.81.02.6-1.20.91.6-1.0-1.1-1.3-1.00.7-1.6-0.3-0.4-0.50.90.3
Stereotopy head waving bouts, day 70.40.51.10.8-0.6-1.00.80.50.80.9-0.50.1-0.1-0.1-1.10.1-0.9
Stereotopy head waving duration, day 70.50.62.30.7-0.4-1.01.00.50.81.0-0.6-0.3-0.2-0.1-1.50.1-1.1
Locomotion velocity, session 80.10.21.0-0.30.60.4-0.1-0.3-0.3-0.10.1-1.0-0.2-0.2-0.50.1-0.1
Locomotion distance, session 81.62.37.5-1.61.22.1-1.3-1.6-1.7-1.11.1-2.7-1.0-1.1-2.00.90.1
Degree of sensitization distance0.30.30.7-0.60.30.8-0.7-0.5-0.7-0.80.5-0.2-0.1-0.20.60.10.8
Degree of sensitization stereotypy0.60.71.91.0-0.6-1.41.10.81.11.1-0.70.50.00.1-0.60.1-0.7
Conditioned locomotion1.31.53.51.4-0.3-1.91.61.41.51.5-1.21.40.70.70.6-1.1-0.7
Cocaine response after cond. corrected0.10.10.50.4-0.7-0.40.10.10.20.00.10.6-0.0-0.30.30.20.3
Cocaine response after cond. not corrected0.30.31.20.6-0.6-0.60.30.40.40.2-0.11.10.3-0.01.1-0.20.6
Cocaine response before conditioning0.00.00.3-0.2-0.00.1-0.1-0.1-0.2-0.10.10.10.00.00.5-0.20.3
Saline control response0.40.53.3-0.20.2-0.00.5-0.10.00.6-0.2-1.5-0.4-0.3-1.80.1-1.0
Bone: connectivity density1.11.73.61.11.3-1.11.01.31.21.0-1.31.91.51.61.5-1.4-0.5
Bone: cortical apparent density0.20.30.8-0.30.10.6-0.5-0.5-0.5-0.50.5-0.4-0.5-0.6-0.80.90.1
Bone: cortical area2.03.06.8-1.9-2.61.6-2.1-1.8-1.7-2.12.0-0.5-1.5-1.6-0.41.31.7
Bone: cortical porosity0.40.51.2-0.5-0.90.5-0.4-0.7-0.6-0.40.6-1.1-0.8-0.8-1.10.30.2
Bone: cortical porosity0.91.01.7-0.9-1.30.8-0.8-1.0-0.9-0.81.0-1.3-1.2-1.1-1.10.50.6
Bone: cortical thickness1.62.75.6-1.6-2.41.5-2.1-1.6-1.6-2.11.9-0.2-1.3-1.5-0.21.51.7
Bone: cortical thickness1.21.54.6-0.9-2.20.7-1.3-1.0-1.0-1.31.40.1-1.2-1.40.40.71.8
Bone: cortical tissue density0.20.30.7-0.30.20.6-0.5-0.5-0.5-0.50.5-0.5-0.5-0.6-0.80.90.1
Condit. Reinf. active minus inactive responses2.73.16.1-1.8-0.42.1-1.7-1.9-1.9-1.61.6-2.5-1.6-1.6-2.01.80.7
Condit. Reinf. active-inactive response ratio6.57.19.9-2.8-1.33.1-2.9-2.9-2.9-2.82.7-2.9-2.6-2.5-2.42.91.6
Condit. Reinf. active responses0.70.93.5-0.70.31.0-0.5-0.9-0.9-0.40.6-1.9-0.8-0.8-1.51.1-0.0
Condit. Reinf. inactive responses1.51.73.11.60.7-1.71.71.51.61.7-1.50.91.21.10.6-1.0-1.1
Incentive salience index mean1.72.13.2-1.5-0.61.8-1.5-1.6-1.6-1.51.5-1.8-1.4-1.4-1.31.60.7
Condit. Reinf. lever presses0.10.10.2-0.0-0.40.2-0.3-0.3-0.2-0.30.3-0.3-0.2-0.3-0.40.4-0.2
Condit. Reinf. active minus inactive responses0.20.31.7-0.2-1.30.0-0.5-0.2-0.1-0.50.51.0-0.2-0.20.30.40.5
Condit. Reinf. active-inactive response ratio0.30.30.8-0.3-0.90.4-0.8-0.4-0.4-0.80.60.8-0.3-0.30.20.80.6
Condit. Reinf. active responses0.50.62.6-0.7-1.60.4-0.9-0.6-0.6-0.90.90.7-0.5-0.70.40.31.0
Condit. Reinf. inactive responses0.50.61.4-1.2-1.00.8-0.8-0.9-0.9-0.80.8-0.6-0.7-0.9-0.40.10.7
Condit. Reinf. lever presses0.40.51.6-0.6-1.30.4-0.8-0.5-0.6-0.90.80.5-0.4-0.50.80.71.1
Condit. Reinf. lever reinforcers received0.30.52.1-0.5-1.40.3-0.7-0.4-0.4-0.80.70.8-0.4-0.50.60.11.0
Conditioned reinforcement - actives0.50.52.70.30.4-0.30.50.20.40.6-0.4-0.70.20.3-1.60.6-1.3
Conditioned reinforcement - inactives0.80.91.61.10.7-1.11.20.91.11.3-1.00.10.60.6-0.3-1.2-1.2
Conditioned locomotion1.61.93.91.11.5-1.21.41.41.41.5-1.60.71.71.7-0.1-0.6-2.0
Patch foraging indifference point 0 sec0.61.03.50.81.9-0.40.80.90.70.9-1.10.31.31.30.6-0.6-1.0
Patch foraging indifference point AUC0.50.61.2-1.0-0.90.8-1.1-0.8-0.8-1.10.90.1-0.6-0.60.00.50.8
Delay disc. indifference point, 0s delay1.41.52.61.11.3-1.21.31.31.31.4-1.40.51.61.40.2-0.5-1.6
Delay disc. indifference point, 16s delay0.10.10.5-0.60.40.5-0.2-0.3-0.4-0.20.1-0.6-0.10.1-0.20.70.1
Delay disc. indifference point, 2s delay2.62.84.11.81.2-2.02.01.91.92.0-1.91.11.71.70.6-1.5-1.7
Delay disc. indifference point, 24s delay1.21.12.01.20.9-1.11.21.11.11.1-1.10.61.01.11.1-1.4-0.5
Delay disc. indifference point, 4s delay0.10.10.40.20.6-0.10.20.20.10.2-0.30.10.20.30.6-0.40.2
Delay disc. indifference point, 8s delay0.30.31.8-0.50.40.30.2-0.3-0.30.20.0-1.3-0.4-0.2-0.90.0-0.1
Indifference point function ln k0.60.93.5-0.90.51.2-0.7-1.0-1.0-0.60.6-1.9-0.6-0.7-1.11.00.1
Indifference point function log k0.60.93.5-0.90.51.2-0.7-1.0-1.0-0.60.6-1.9-0.6-0.7-1.11.00.1
Patch foraging total patch changes 0 sec0.40.62.80.41.7-0.10.60.60.40.6-0.80.21.11.00.5-0.4-0.8
Patch foraging total patch changes 12 sec0.20.20.5-0.50.00.6-0.7-0.4-0.5-0.70.50.1-0.00.00.6-0.20.6
Patch foraging total patch changes 18 sec0.20.21.10.11.10.5-0.3-0.1-0.2-0.2-0.1-0.20.60.40.1-0.9-0.4
Patch foraging total patch changes 24 sec0.20.31.4-0.40.20.6-0.4-0.5-0.5-0.40.4-0.8-0.2-0.3-1.20.1-0.4
Patch foraging total patch changes 6 sec0.30.52.60.00.70.5-0.60.0-0.3-0.60.10.90.90.61.6-0.80.5
Patch foraging time to switch 0 sec1.11.72.71.61.0-1.61.61.51.61.6-1.40.71.11.20.4-1.1-1.3
Patch foraging water rate 0 sec0.61.01.7-1.2-0.81.2-1.3-1.1-1.2-1.31.1-0.1-0.8-0.80.01.01.1
Patch foraging water rate 12 sec2.64.05.2-2.1-1.62.2-2.1-2.2-2.2-2.12.1-1.8-2.2-2.3-1.61.91.6
Patch foraging water rate 18 sec1.92.54.5-1.8-1.41.9-2.1-1.7-1.8-2.11.8-0.5-1.4-1.30.01.41.7
Patch foraging water rate 24 sec2.13.05.2-1.9-0.62.3-2.0-1.9-2.1-2.01.7-1.6-1.4-1.5-0.92.11.3
Patch foraging water rate 6 sec7.611.115.1-3.6-2.03.9-3.7-3.7-3.8-3.63.5-2.9-3.5-3.5-2.13.32.9
Seeking ratio, delayed vs. immediate footshock3.64.28.12.21.3-2.22.12.22.12.1-2.01.82.02.02.1-2.8-1.1
Distance traveled before self-admin0.10.10.50.4-0.7-0.30.00.10.20.00.10.6-0.2-0.20.2-0.7-0.1
Distance traveled after self-admin0.00.00.10.20.20.2-0.3-0.0-0.1-0.30.10.3-0.10.10.2-0.4-0.0
Extensor digitorum longus weight4.216.437.1-4.0-6.13.1-4.0-4.1-3.7-4.04.5-2.3-4.7-4.7-2.63.83.6
Bone: elastic displacement0.81.01.9-0.9-1.40.9-1.2-1.0-1.0-1.21.1-0.7-0.9-1.0-0.60.70.8
Bone: elastic work2.53.35.5-1.8-2.31.7-2.2-1.8-1.8-2.22.1-0.7-1.9-1.8-0.31.22.0
Bone: endosteal estimation0.10.30.8-0.9-0.90.5-0.4-0.5-0.5-0.40.5-0.4-0.6-0.5-0.30.10.4
Bone: endosteal perimeter0.20.51.2-0.8-1.10.5-0.5-0.7-0.6-0.50.6-0.9-0.7-0.7-0.90.30.1
Epididymis fat weight1.12.55.4-1.9-0.91.8-1.5-1.7-1.7-1.41.4-2.3-1.6-1.4-1.81.50.5
Delta time in closed arm before/after self-admin0.70.74.7-0.5-0.10.5-0.2-0.6-0.4-0.10.3-1.0-0.6-0.7-2.21.2-0.7
Delta time in open arm before/after self-admin0.20.21.2-0.0-0.5-0.00.1-0.2-0.00.10.1-1.0-0.3-0.4-1.1-0.3-0.4
Diff in mean of infusions in LGA sessions0.50.61.3-0.60.71.1-0.9-0.6-0.9-1.00.60.1-0.3-0.20.90.41.1
Delay discount exponential model param0.20.20.6-0.2-0.80.3-0.6-0.3-0.3-0.60.50.2-0.3-0.5-0.20.50.2
Extinction: sum of active levers before priming1.71.73.9-1.2-1.21.2-1.5-1.3-1.4-1.61.5-0.2-1.3-1.20.90.82.0
Active lever presses in extinction session 60.30.32.30.31.50.10.20.30.20.2-0.50.30.70.70.30.0-0.4
Bone: final force0.60.91.5-1.1-0.81.2-1.2-1.1-1.1-1.21.1-0.8-0.9-0.9-0.50.40.8
Bone: final moment0.60.91.6-1.1-0.91.1-1.3-1.0-1.1-1.31.1-0.6-0.9-0.8-0.20.31.0
Food consumed during 24 hour testing period2.53.04.0-2.0-1.51.9-1.9-1.9-1.9-1.91.9-1.6-1.9-1.9-0.81.11.8
Glucose1.42.03.0-1.7-1.21.5-1.6-1.5-1.6-1.61.6-1.1-1.5-1.4-0.21.11.6
Heart weight0.40.51.6-1.0-1.30.4-0.5-0.7-0.6-0.60.7-0.6-1.0-0.7-0.50.50.6
Delay discount hyperbolic model param0.40.40.8-0.5-0.90.6-0.8-0.6-0.6-0.80.7-0.1-0.6-0.7-0.40.70.4
Intermittent access intake day 1-15 change0.20.20.50.70.6-0.40.40.50.40.4-0.50.40.70.50.5-0.1-0.6
Intermittent access intake escalation0.10.10.30.60.2-0.30.30.40.30.3-0.30.40.50.30.50.1-0.3
Intermittent access intake escalation 20.00.00.20.3-0.2-0.1-0.10.10.1-0.1-0.00.30.20.20.40.0-0.0
Intermitt. access day 1 inactive lever presses0.20.20.80.30.5-0.40.60.30.30.5-0.40.10.40.20.7-0.90.1
Intermitt. access day 15 inactive lever presses0.70.71.5-1.0-1.10.6-0.5-0.9-0.8-0.60.8-0.9-1.0-1.2-0.20.81.0
Intermitt. access escalation Index0.30.31.00.4-0.8-0.80.50.40.50.4-0.21.0-0.2-0.10.60.10.4
Intermittent access day 1 total infusions3.43.95.0-2.2-1.52.2-2.0-2.2-2.2-2.02.1-1.9-2.2-2.1-1.71.71.5
Intermittent access day 15 total infusions1.21.41.9-1.2-0.91.4-1.3-1.3-1.4-1.31.3-1.1-1.1-1.2-0.71.10.8
Intermittent access terminal intake (last 3 days)1.71.93.0-1.4-0.61.7-1.5-1.6-1.6-1.51.5-1.7-1.2-1.2-1.31.20.6
Intermittent access total infusions3.33.75.1-2.1-1.32.3-2.1-2.2-2.2-2.12.1-2.1-1.9-1.8-1.61.51.3
Intermittent access day 1 locomotion1.21.31.9-1.4-1.01.3-1.3-1.3-1.3-1.21.3-1.0-1.1-1.1-0.91.00.8
Intermittent access day 15 total locomotion0.10.10.20.20.1-0.10.10.20.10.1-0.20.20.40.20.4-0.2-0.4
Intermittent access total locomotion0.80.91.3-0.9-1.01.0-1.2-1.0-1.0-1.21.1-0.4-0.8-1.0-0.30.80.8
Intermittent access standard deviation0.10.10.3-0.2-0.20.5-0.6-0.3-0.4-0.50.4-0.1-0.0-0.0-0.40.3-0.2
Left kidney weight1.64.66.4-2.4-1.82.4-2.5-2.4-2.4-2.52.5-1.8-2.2-2.2-0.81.52.0
Right kidney weight2.05.57.1-2.7-2.22.5-2.6-2.6-2.5-2.62.6-2.3-2.5-2.4-1.51.71.7
Cocaine induced anxiety0.80.92.00.51.4-0.60.90.90.81.0-1.10.31.21.20.1-0.8-1.2
Post-drug Anxiety0.10.20.8-0.30.60.10.10.2-0.00.1-0.30.40.50.50.90.10.2
Baseline Anxiety1.11.13.9-0.7-0.90.8-1.1-0.8-1.0-1.21.10.5-0.9-0.91.31.12.0
Tail length0.20.61.7-0.5-1.20.5-0.7-0.7-0.5-0.60.8-0.7-0.9-0.8-1.30.50.0
Length with tail0.62.35.4-1.7-2.31.1-1.6-1.5-1.3-1.61.7-0.3-1.8-1.6-0.71.41.6
Length without tail0.51.13.0-1.2-1.40.7-1.1-0.8-0.9-1.21.00.7-0.9-0.70.90.81.7
Times rat made contact with spout0.30.41.5-0.2-0.10.6-0.7-0.4-0.6-0.80.60.7-0.3-0.41.0-0.11.2
Lifetime Intake2.73.14.4-2.0-1.02.0-1.8-2.0-1.9-1.71.8-2.1-1.7-1.6-1.91.70.9
Liver weight, left0.20.31.5-0.00.60.2-0.0-0.00.00.1-0.2-0.40.10.3-1.20.8-1.0
Liver weight, right0.00.10.20.10.50.1-0.20.10.1-0.1-0.10.30.20.3-0.30.2-0.4
Locomotor activity0.10.20.6-0.6-0.00.6-0.4-0.4-0.6-0.50.40.2-0.2-0.20.60.10.8
Locomotor testing distance0.61.02.0-1.4-0.71.1-1.0-1.1-1.2-1.01.0-0.5-1.1-0.9-0.10.81.3
Locomotor testing rearing1.92.96.7-1.9-0.52.1-2.0-1.8-2.1-2.11.8-0.3-1.4-1.40.91.22.6
Locomotion in novel chamber3.64.59.72.21.3-2.11.82.32.11.7-2.03.12.22.23.0-1.9-0.7
Locomotion in novel chamber post-restriction0.20.30.80.7-0.0-0.80.60.50.60.5-0.40.90.10.20.8-0.20.2
Fecal boli incidents, locomotor time 10.20.20.60.20.4-0.30.60.30.40.6-0.4-0.3-0.00.3-0.70.0-0.8
Change in fecal boli incidents, locomotor task0.70.61.3-0.8-0.60.8-0.9-0.8-0.9-0.90.9-0.7-0.8-0.90.40.61.1
Time >=10cm from walls, locomotor time 10.50.52.50.50.8-0.1-0.00.50.2-0.1-0.31.21.10.91.6-0.40.1
Bouts of movement, locomotor time 10.20.21.1-0.0-0.00.1-0.3-0.0-0.2-0.30.10.60.30.21.0-0.60.8
Total resting periods, locomotor time 10.10.10.4-0.30.00.3-0.3-0.2-0.3-0.40.20.2-0.00.10.6-0.30.7
Rest time, locomotor task time 10.30.30.90.5-0.5-0.90.70.60.70.6-0.50.80.10.3-0.00.7-0.2
Distance moved, locomotor task time 10.50.50.9-0.9-0.11.0-0.9-0.8-0.9-0.90.7-0.7-0.1-0.50.40.00.9
Vertical activity count, locomotor time 10.20.20.80.10.40.3-0.2-0.1-0.2-0.30.1-0.10.70.10.7-0.90.2
Time >=10cm from walls, locomotor time 21.41.54.1-1.3-1.11.0-0.9-1.2-1.1-0.91.1-2.0-1.2-1.3-1.51.30.3
Bouts of movement, locomotor time 20.91.01.41.11.0-1.01.11.11.11.1-1.10.71.01.20.8-0.8-0.9
Total resting periods, locomotor time 21.11.21.61.21.0-1.11.21.21.11.2-1.20.81.11.30.9-1.1-0.9
Rest time, locomotor task time 21.21.43.01.3-0.0-1.51.21.31.31.1-1.01.71.10.91.3-1.1-0.3
Distance moved, locomotor task time 20.20.31.2-0.40.40.6-0.3-0.4-0.4-0.20.2-1.10.1-0.3-0.80.9-0.2
Vertical activity count, locomotor time 20.00.00.30.20.10.10.0-0.0-0.00.0-0.1-0.50.3-0.1-0.30.3-0.2
Light reinforcement 11.93.45.9-2.4-1.02.3-2.1-2.1-2.2-2.01.9-2.0-1.5-1.8-1.21.21.4
Light reinforcement 20.10.10.4-0.6-0.40.2-0.3-0.3-0.3-0.30.3-0.1-0.2-0.30.20.50.5
Bone: marrow area0.10.20.7-0.8-0.80.4-0.4-0.5-0.5-0.40.4-0.4-0.5-0.5-0.20.00.4
Bone: maximum diameter0.40.82.2-1.2-1.50.8-1.0-0.9-0.9-1.11.0-0.2-0.7-0.7-0.10.40.8
Bone: maximum force0.50.81.5-1.2-0.71.2-1.2-1.0-1.0-1.20.9-0.6-0.7-0.6-0.70.60.5
Bone: maximum moment0.50.81.5-1.2-0.91.1-1.2-1.0-1.0-1.21.0-0.4-0.7-0.6-0.30.40.7
Mean time between licks in bursts0.10.10.6-0.20.70.5-0.3-0.2-0.3-0.30.0-0.50.30.20.10.4-0.1
Mean num. licks in bursts0.91.12.91.1-0.5-1.30.91.01.00.8-0.61.70.40.41.6-1.30.5
Cd content in liver0.30.40.6-0.6-0.30.8-0.8-0.7-0.7-0.80.7-0.7-0.4-0.5-0.20.50.4
Co content in liver2.22.64.7-1.7-1.21.7-1.5-1.8-1.7-1.41.6-2.2-1.7-1.8-2.01.20.6
Cu content in liver1.21.44.81.32.2-0.50.81.00.80.8-1.11.01.51.51.2-1.2-0.8
Fe content in liver2.63.24.31.91.7-1.81.81.91.81.8-1.91.52.02.11.3-1.6-1.5
K content in liver1.61.63.51.60.8-1.31.11.31.21.1-1.11.21.31.11.9-1.6-0.5
Mg content in liver0.50.51.41.00.9-0.50.60.60.60.5-0.60.50.70.61.1-1.2-0.2
Mn content in liver0.50.51.8-0.2-1.10.2-0.7-0.4-0.4-0.80.70.7-0.3-0.51.30.11.3
Na content in liver0.00.00.00.0-0.1-0.10.10.10.10.1-0.1-0.0-0.00.00.10.00.1
Rb content in liver0.20.31.7-0.00.40.5-0.2-0.4-0.3-0.10.2-0.9-0.4-0.4-1.30.4-0.6
Se content in liver0.70.81.91.10.5-1.00.90.90.90.8-0.80.80.90.81.1-1.4-0.4
Sr content in liver0.40.41.0-0.6-1.00.1-0.3-0.4-0.4-0.30.5-0.1-0.9-0.70.10.90.9
Zn content in liver5.76.313.32.83.7-1.71.92.52.11.9-2.52.43.33.02.5-2.3-1.8
Bone: minimum diameter2.95.48.4-2.6-2.92.3-2.5-2.5-2.4-2.52.6-1.9-2.4-2.4-1.41.62.0
Time in familiar zone, hab. session 10.30.31.10.50.4-0.40.50.40.50.6-0.5-0.10.40.5-0.8-0.3-1.0
Time in novel zone, hab. session 10.10.10.50.2-0.3-0.40.20.20.20.1-0.10.50.10.00.7-0.00.3
Total zone transitions, hab. session 11.42.08.3-1.3-0.11.3-0.7-1.3-1.2-0.60.9-2.6-1.2-1.3-2.91.2-0.4
Total locomotion distance, hab. session 10.20.31.8-0.40.60.5-0.1-0.4-0.4-0.10.1-1.1-0.1-0.2-1.30.4-0.5
Locomotion velocity, hab. session 10.30.41.2-0.70.30.9-0.5-0.7-0.7-0.50.5-1.1-0.4-0.5-0.90.50.0
Time in familiar zone, hab. session 20.70.72.70.1-1.5-0.4-0.30.10.1-0.40.41.4-0.3-0.31.7-0.11.3
Time in novel zone, hab. session 20.70.72.70.51.6-0.00.60.30.30.7-0.7-0.80.60.6-1.1-0.4-1.4
Total zone transitions, hab. session 21.31.75.0-1.30.11.5-1.0-1.4-1.3-0.91.0-2.2-1.1-1.1-2.20.8-0.1
Total locomotion distance, hab. session 20.70.91.5-1.1-0.21.2-1.0-1.1-1.1-1.01.0-1.0-0.9-0.9-0.50.70.8
Locomotion velocity, hab. session 20.40.51.0-0.90.11.0-0.8-0.8-0.9-0.70.7-0.9-0.7-0.7-0.50.50.5
Novel to familiar place preference ratio0.10.20.3-0.50.30.6-0.4-0.4-0.5-0.40.4-0.6-0.3-0.2-0.0-0.10.4
Novelty place preference0.20.20.5-0.60.10.7-0.5-0.5-0.6-0.50.5-0.6-0.4-0.30.1-0.20.6
Time in novel zone, NPP test0.30.30.5-0.60.00.7-0.6-0.6-0.7-0.60.5-0.5-0.4-0.30.2-0.10.7
Total zone transitions, NPP test2.23.15.8-1.9-0.72.1-1.7-2.0-2.0-1.71.7-2.4-1.7-1.9-2.01.20.8
Total locomotion distance, NPP test0.60.81.6-0.9-0.11.3-1.2-1.0-1.1-1.21.0-0.7-0.6-0.8-0.40.60.7
Locomotion velocity, NPP test0.81.12.1-1.1-0.31.5-1.4-1.2-1.3-1.41.2-0.7-0.8-1.0-0.30.61.0
Intraocular pressure0.50.71.40.8-0.1-1.21.01.01.11.0-0.90.80.70.7-0.10.2-1.0
Delta distance traveled before/after self-admin0.20.20.8-0.30.90.7-0.4-0.3-0.5-0.30.2-0.7-0.00.0-0.30.10.0
Delta ambulatory time before/after self-admin0.20.30.8-0.40.90.8-0.5-0.5-0.6-0.50.3-0.7-0.1-0.1-0.30.40.2
Parametrial fat weight0.40.91.60.90.7-0.80.71.00.90.7-0.91.01.11.20.9-1.0-0.9
Pavlov. Cond. lever latency1.31.62.3-1.3-1.41.1-1.2-1.3-1.2-1.21.3-0.9-1.5-1.5-0.61.51.5
Pavlov. Cond. magazine entry latency0.10.21.0-0.3-0.10.2-0.0-0.3-0.20.00.1-0.9-0.4-0.3-1.00.0-0.3
Pavlov. Cond. change in total contacts0.40.41.60.61.3-0.20.60.40.40.7-0.6-0.30.60.6-0.6-0.4-1.0
Pavlov. Cond. index score0.50.61.00.90.7-0.70.70.80.80.7-0.80.60.80.90.5-1.0-0.8
Pavlov. Cond. latency score0.81.01.31.11.0-0.91.01.01.01.0-1.00.81.11.10.6-1.1-1.0
Pavlov. Cond. lever contacts0.30.40.70.70.4-0.50.40.60.50.4-0.50.80.80.70.6-0.7-0.6
Pavlov. Cond. magazine entry number0.20.31.60.30.1-0.40.20.40.30.1-0.30.90.50.41.3-0.30.3
Pavlov. Cond. intertrial magazine entries0.10.20.40.40.5-0.30.30.40.40.3-0.40.40.60.60.2-0.0-0.5
Pavlov. Cond. lever-magazine prob. diff.0.30.40.90.70.6-0.50.50.60.60.5-0.60.50.60.70.6-0.9-0.4
Pavlov. Cond. response bias0.10.10.80.10.10.00.1-0.00.00.1-0.1-0.4-0.00.0-0.9-0.1-0.6
Pavlov. Cond. lever latency1.11.42.41.41.1-1.41.41.31.31.4-1.30.71.01.00.9-1.5-0.8
Pavlov. Cond. magazine entry latency0.10.20.30.30.1-0.60.60.50.50.6-0.50.40.20.40.2-0.1-0.3
Pavlov. Cond. change in total contacts0.20.20.4-0.6-0.20.7-0.7-0.5-0.6-0.60.50.1-0.3-0.1-0.10.60.3
Pavlov. Cond. index score0.10.10.5-0.1-0.5-0.1-0.10.10.1-0.10.00.70.10.20.10.4-0.0
Pavlov. Cond. latency score0.10.10.60.20.0-0.30.20.40.30.2-0.30.80.40.60.20.2-0.3
Pavlov. Cond. lever contacts2.02.83.9-1.9-1.81.7-1.9-1.8-1.7-1.91.8-1.0-1.6-1.5-1.02.01.3
Pavlov. Cond. magazine entry number0.10.10.7-0.20.30.5-0.3-0.4-0.4-0.30.3-0.8-0.2-0.4-0.2-0.10.2
Pavlov. Cond. intertrial magazine entries0.40.61.4-0.4-1.20.4-0.8-0.5-0.5-0.90.80.6-0.4-0.51.0-0.61.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.6-0.0-0.5-0.2-0.10.10.1-0.1-0.00.70.10.30.20.3-0.0
Pavlov. Cond. response bias1.62.23.6-1.7-1.91.4-1.6-1.5-1.5-1.51.6-0.9-1.5-1.4-1.11.71.1
Time in closed arm before self-admin0.30.31.20.61.1-0.30.30.50.40.3-0.60.30.80.70.5-0.4-0.3
Time in closed arm after self-admin0.60.62.90.61.7-0.20.50.60.50.6-0.80.31.01.00.0-0.2-0.9
Time in open arm before self-admin2.22.44.2-1.8-1.91.4-1.7-1.5-1.6-1.71.7-0.4-1.6-1.60.21.22.1
Time in open arm after self-admin1.51.73.8-1.4-2.00.9-1.1-1.3-1.1-1.11.4-1.4-1.5-1.5-1.30.80.8
Bone: periosteal estimation1.12.35.3-1.8-2.31.4-1.7-1.6-1.5-1.71.7-0.7-1.5-1.5-0.51.01.5
Bone: periosteal perimeter1.01.75.1-1.5-2.31.0-1.3-1.3-1.2-1.31.5-0.8-1.4-1.4-0.90.71.0
Bone: post-yield work0.60.92.20.41.2-0.71.00.90.91.0-1.10.11.11.1-0.3-0.7-1.5
Progressive ratio test 1 active lever presses3.94.15.5-2.1-1.62.1-2.0-2.3-2.2-1.92.1-2.2-2.3-2.2-1.91.71.5
Progressive ratio test 1 breakpoint3.53.64.6-2.1-1.42.1-1.9-2.1-2.1-1.92.0-1.9-2.1-2.0-1.61.91.5
Progressive ratio test 1 inactive lever presses0.10.10.3-0.2-0.20.10.1-0.2-0.20.10.2-0.6-0.5-0.5-0.0-0.60.4
Progressive ratio test 2 active lever presses2.32.43.7-1.4-1.91.5-1.8-1.7-1.6-1.81.8-0.9-1.7-1.7-0.81.51.4
Progressive ratio test 2 breakpoint2.73.14.8-1.5-2.21.6-2.0-1.8-1.8-2.02.1-0.9-2.0-1.9-0.61.51.8
Progressive ratio test 2 inactive lever presses0.50.61.5-0.6-1.20.5-0.6-0.8-0.6-0.60.9-0.6-0.9-1.0-0.80.50.5
Incentive Sensitization - Responses0.40.41.21.1-0.2-0.90.50.70.80.5-0.50.70.50.50.2-0.4-0.8
Incentive Sensitization - Breakpoint0.40.41.11.0-0.4-0.90.50.70.80.5-0.40.90.50.40.5-0.4-0.5
Sum of active levers in priming session hrs 5-60.70.75.00.50.6-0.0-0.30.30.0-0.3-0.01.20.30.22.2-0.71.2
Progressive ratio0.20.21.5-0.2-1.2-0.40.10.10.20.10.10.2-0.2-0.30.4-0.40.3
Food seeking constrained by brief footshock1.21.42.4-0.9-1.31.2-1.5-1.2-1.3-1.61.40.0-1.1-1.20.01.11.4
Seeking ratio, punishment vs. effort0.40.51.2-0.30.61.1-0.9-0.7-0.9-0.80.6-0.4-0.4-0.3-0.31.10.5
Retroperitoneal fat weight0.93.15.0-2.2-1.91.9-2.0-1.9-1.9-2.01.9-1.5-1.9-1.7-0.80.91.4
Reaction time number correct0.30.51.3-0.8-0.80.6-0.7-0.7-0.8-0.80.8-0.2-0.8-0.70.30.11.1
Reaction time mean minus median1.41.83.51.70.3-1.91.61.61.71.5-1.41.51.01.00.7-1.0-1.0
Reaction time mean minus median AUC1.11.52.81.60.3-1.71.41.41.51.3-1.21.51.00.90.9-1.0-0.7
Reaction time num false alarms0.50.72.60.20.4-0.61.00.40.61.1-0.7-0.90.30.3-1.6-0.5-1.4
Reaction time num false alarms AUC0.40.63.6-0.0-0.2-0.50.80.20.40.9-0.4-1.1-0.10.1-1.9-0.3-1.2
Reaction time trials correct on left0.30.51.3-0.8-0.80.6-0.7-0.7-0.8-0.80.8-0.2-0.8-0.70.30.11.1
Reaction time trials on left0.30.41.1-0.6-0.80.5-0.6-0.6-0.6-0.60.7-0.0-0.7-0.60.4-0.01.1
Reaction time mean0.50.62.00.8-0.4-1.20.80.80.90.8-0.61.40.30.41.0-0.20.1
Reaction time mean AUC0.30.41.40.6-0.6-1.00.70.60.70.6-0.41.20.00.10.90.10.3
Median of all reaction times0.20.20.80.1-0.8-0.50.10.10.20.00.10.9-0.3-0.20.80.40.8
Reaction time omissions2.83.86.12.20.6-2.52.22.22.32.2-2.02.11.81.71.1-2.1-1.4
Reaction time false alarm rate0.60.82.40.50.4-0.81.10.60.81.2-0.9-0.60.50.6-1.4-0.4-1.5
Reaction time premature initiation rate1.31.73.1-1.5-1.41.1-1.1-1.3-1.2-1.01.2-1.7-1.3-1.4-1.81.40.4
Reaction time premature initiations1.72.53.4-1.8-1.81.3-1.3-1.6-1.5-1.31.5-1.8-1.7-1.8-1.81.50.8
Std. dev. reaction times2.33.25.42.20.7-2.32.02.02.22.0-1.82.01.51.51.1-1.4-1.3
Reaction time trials completed0.30.41.1-0.6-0.80.5-0.6-0.6-0.6-0.60.7-0.0-0.7-0.60.4-0.01.1
Reaction time trials AUC0.40.51.2-0.8-0.90.7-0.8-0.7-0.8-0.80.8-0.1-0.8-0.70.20.21.1
Run reversals in cocaine runway, females0.20.21.20.30.2-0.10.10.10.00.0-0.00.40.1-0.01.1-0.80.7
Run reversals in cocaine runway, males0.90.92.2-0.9-0.41.0-0.9-1.0-1.1-1.01.0-0.6-1.2-1.10.20.31.5
Latency to leave start box in cocaine runway0.10.10.80.10.90.00.20.20.00.2-0.30.20.40.50.7-0.3-0.0
Latency to leave start box in cocaine runway, F0.10.10.4-0.10.60.4-0.1-0.1-0.2-0.1-0.0-0.20.30.10.00.2-0.2
Latency to leave start box in cocaine runway, M2.22.15.51.31.4-1.21.01.51.20.9-1.32.11.51.82.3-1.6-0.3
Std. dev. time between licks in bursts0.80.93.7-0.91.71.4-0.6-0.7-1.0-0.50.3-1.9-0.0-0.1-0.90.6-0.3
Total sessions with >9 infusions2.72.99.3-1.8-0.31.8-1.2-1.7-1.6-1.01.3-2.8-1.4-1.4-3.12.0-0.1
Short access day 1 total inactive lever presses0.20.21.0-0.50.60.6-0.3-0.5-0.5-0.20.3-1.0-0.2-0.2-0.6-0.60.0
Short access day 10 total inactive lever presses3.94.38.02.02.3-2.02.42.12.02.3-2.30.92.22.01.4-2.8-1.7
Short access day 1 total infusions0.70.73.00.21.50.20.40.10.10.5-0.4-1.20.40.5-1.7-0.2-1.5
Short access day 10 total infusions1.92.14.7-1.7-0.41.6-1.2-1.6-1.6-1.11.3-2.2-1.5-1.3-1.91.60.5
Short access total infusions1.92.25.5-1.6-0.11.7-1.1-1.5-1.5-1.01.2-2.2-1.3-1.2-2.31.70.1
Short access day 1 locomotion0.60.72.8-0.11.70.7-0.0-0.1-0.20.1-0.2-1.10.60.5-1.50.4-1.3
Short access day 10 total locomotion0.10.10.60.10.80.3-0.10.0-0.1-0.1-0.10.20.50.40.1-0.2-0.3
Short access total locomotion0.10.10.6-0.40.80.5-0.2-0.1-0.3-0.1-0.1-0.20.40.4-0.20.4-0.4
One hour access (0.3 mA shock)0.30.40.8-0.5-0.90.5-0.8-0.6-0.6-0.90.80.1-0.5-0.40.30.10.6
Compulsive drug intake0.70.73.10.6-0.4-0.80.40.60.60.3-0.31.10.30.31.8-1.50.4
One hour access (shock baseline)0.50.60.8-0.8-0.40.9-0.9-0.8-0.8-0.80.8-0.7-0.7-0.6-0.60.80.4
Social response proportion0.80.91.51.00.6-1.11.21.01.11.2-1.1-0.10.90.70.4-1.1-0.9
Social responses0.20.21.6-0.3-0.40.1-0.3-0.0-0.2-0.30.20.70.10.11.3-0.30.7
Social time1.92.53.71.70.8-1.91.71.81.81.6-1.71.71.71.71.3-1.0-1.2
Soleus weight0.72.04.9-1.4-2.21.0-1.2-1.4-1.2-1.21.5-1.3-1.6-1.8-1.21.31.0
Bone: stiffness0.81.22.4-1.6-0.81.4-1.3-1.2-1.3-1.31.2-0.8-0.9-0.9-0.60.80.9
Tibialis anterior weight5.619.041.1-4.6-6.43.4-4.4-4.4-4.0-4.44.8-2.1-5.0-4.9-2.04.14.4
Time to tail flick, vehicle, before self-admin0.30.30.50.60.6-0.50.70.50.50.7-0.6-0.20.50.7-0.0-0.6-0.7
Time to tail flick, vehicle, after self-admin1.21.21.71.10.4-1.31.21.31.31.2-1.31.01.31.20.4-0.5-1.3
Time to tail flick, test, before self-admin2.92.83.81.71.0-1.91.91.91.91.9-1.81.41.91.81.1-1.5-1.4
Time to tail flick, test, after self-admin0.30.30.6-0.6-0.00.8-0.6-0.7-0.7-0.60.5-0.7-0.5-0.6-0.60.60.3
Delta time to tail flick, vehicle, before/after SA0.10.10.30.00.2-0.10.10.20.20.2-0.30.20.30.2-0.40.4-0.6
Delta time to tail flick, test, before/after SA3.22.93.8-1.7-0.72.0-1.7-1.8-1.8-1.61.6-1.9-1.9-1.8-1.71.91.0
Tibia length0.71.87.5-1.2-2.70.6-1.3-1.1-1.0-1.41.50.3-1.4-1.50.21.11.7
Ambulatory time before self-admin0.10.10.80.4-0.6-0.30.00.10.20.00.10.5-0.2-0.10.2-0.9-0.1
Ambulatory time after self-admin0.20.20.60.60.7-0.20.20.30.30.2-0.30.30.30.5-0.2-0.4-0.7
Bone: tissue strength0.70.71.4-1.2-0.31.1-1.1-0.9-1.0-1.10.8-0.5-0.6-0.5-0.30.50.7
Total heroin consumption0.10.10.30.00.30.1-0.10.10.0-0.1-0.00.30.20.20.6-0.40.2
Bone: trabecular number1.11.72.21.30.9-1.51.41.41.51.4-1.41.41.41.40.3-1.3-1.3
Bone: trabecular spacing0.40.51.6-0.3-0.40.6-0.8-0.5-0.6-0.90.60.3-0.3-0.51.20.51.2
Bone: trabecular thickness0.10.10.9-0.2-0.2-0.00.1-0.2-0.00.10.1-0.5-0.5-0.2-1.0-0.2-0.2
Bone: trabecular tissue density0.10.10.6-0.00.1-0.10.2-0.10.00.2-0.0-0.5-0.3-0.3-0.70.0-0.2
Water consumed over 24 hours0.70.81.2-0.8-0.61.0-1.1-1.0-1.0-1.11.1-0.5-0.9-1.1-0.60.70.9
Number of responses in last shaping day0.80.83.6-0.9-0.10.9-0.5-0.8-0.7-0.40.5-1.9-0.7-0.6-1.90.2-0.4