Hub : Genes

LOC102555623

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS XR_005501333.2 0.25 0.09 0.0e+00 0.19 0.21 0.21 0.17 1.3e-20 1.8e-22 3.3e-23 2.8e-18
2 Liver gene expression LOC102555623 0.57 0.13 0.0e+00 0.4 0.39 0.41 0.41 8.3e-48 4.9e-46 2.7e-48 2.4e-48
3 pVTA alternative TSS XR_352069.4 0.08 0.04 2.1e-04 0.03 0.05 0.03 0.04 4.0e-03 7.5e-05 1.4e-03 4.3e-04
4 Liver alternative TSS XR_005501335.2 0.18 0.08 0.0e+00 0.12 0.14 0.14 0.15 8.9e-14 4.2e-15 1.2e-15 6.2e-16
5 PL gene expression LOC102555623 0.05 0.02 2.8e-05 0.05 0.05 0.04 0.04 7.7e-06 6.6e-06 9.5e-06 1.1e-05
6 Liver alternative TSS XR_005501334.2 0.28 0.1 0.0e+00 0.22 0.21 0.21 0.21 1.5e-23 5.1e-23 3.5e-23 3.4e-23
7 Adipose gene expression LOC102555623 0.21 0.09 0.0e+00 0.09 0.15 0.15 0.16 1.8e-10 1.4e-16 2.2e-16 7.1e-18
8 BLA gene expression LOC102555623 0.09 0.05 1.8e-04 0.04 0.04 0.04 0.05 2.8e-03 4.2e-03 2.4e-03 1.1e-03
9 NAcc gene expression LOC102555623 0.06 0.03 7.1e-10 0.07 0.06 0.06 0.07 2.3e-11 4.4e-10 7.1e-10 3.1e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.81.43.61.1-1.1-1.0-1.2-1.91.00.1-1.5-1.1
Area under the delay curve0.10.10.20.2-0.3-0.5-0.40.40.40.0-0.4-0.3
BMI with tail1.96.510.6-3.03.13.32.81.0-2.82.52.21.2
BMI without tail2.16.311.2-2.72.93.32.60.6-2.92.62.31.6
Body weight2.510.916.4-3.83.94.03.71.2-3.73.62.52.0
Weight adjusted by age0.10.21.2-0.10.00.1-0.11.10.1-0.00.8-0.1
Bone surface0.30.62.30.6-0.7-0.5-0.9-1.50.70.1-0.6-0.6
Bone volume0.30.52.40.7-0.7-0.5-0.9-1.50.50.2-0.4-0.2
Breakpoint value in progressive ratio session0.40.51.3-0.50.60.30.8-0.3-0.41.0-1.1-0.6
Number of licking bursts0.50.91.8-1.31.20.81.31.1-0.70.6-0.4-0.4
Context. condit. distance diff. score0.40.51.90.1-0.3-0.5-0.1-0.20.6-0.3-1.3-1.4
Locomotion velocity, session 12.32.54.6-1.61.51.41.62.1-1.60.71.31.9
Locomotion distance, session 12.12.69.2-1.81.61.21.73.0-1.20.70.91.1
Locomotion velocity, session 20.20.20.8-0.50.40.30.30.9-0.30.3-0.40.1
Locomotion distance, session 22.23.114.8-1.61.40.91.53.8-1.10.21.21.7
Locomotion velocity, session 31.51.83.9-1.41.30.91.42.0-1.10.21.31.6
Locomotion distance, session 30.20.20.8-0.50.40.20.40.9-0.1-0.20.30.0
Stereotopy head waving bouts, day 31.01.22.9-0.81.00.91.11.0-1.20.31.31.7
Stereotopy head waving duration, day 31.51.82.5-1.41.41.41.50.9-1.50.91.31.6
Locomotion velocity, session 71.31.52.5-1.51.41.11.41.6-1.11.10.60.5
Locomotion distance, session 70.70.92.5-1.41.10.81.01.6-0.40.60.0-0.8
Stereotopy head waving bouts, day 70.80.93.90.7-0.4-0.3-0.30.5-0.1-1.11.42.0
Stereotopy head waving duration, day 71.01.24.90.6-0.3-0.4-0.20.9-0.2-1.21.82.2
Locomotion velocity, session 80.20.21.3-0.50.30.10.41.1-0.2-0.00.20.1
Locomotion distance, session 81.62.39.6-1.91.50.91.83.1-0.90.6-0.10.2
Degree of sensitization distance0.40.41.4-0.60.40.40.4-0.0-0.10.8-0.9-1.2
Degree of sensitization stereotypy0.80.82.71.0-0.7-0.6-0.6-0.00.1-1.11.11.6
Conditioned locomotion1.01.12.21.5-1.3-1.0-1.4-1.20.7-1.00.40.5
Cocaine response after cond. corrected0.10.10.40.5-0.3-0.0-0.3-0.60.00.3-0.40.4
Cocaine response after cond. not corrected0.30.30.90.7-0.6-0.2-0.7-1.00.20.4-0.7-0.2
Cocaine response before conditioning0.00.10.2-0.20.10.30.00.0-0.10.40.2-0.4
Saline control response1.01.44.7-0.60.50.30.41.9-0.4-0.72.21.7
Bone: connectivity density1.72.64.31.5-1.6-1.6-1.6-1.71.6-0.6-2.1-1.9
Bone: cortical apparent density0.10.20.4-0.30.40.40.60.4-0.40.7-0.3-0.1
Bone: cortical area1.11.73.5-1.31.41.91.0-0.9-1.21.81.00.7
Bone: cortical porosity0.80.81.7-0.80.81.00.71.0-0.80.21.21.3
Bone: cortical porosity1.41.52.6-1.11.11.31.01.1-1.20.61.51.6
Bone: cortical thickness0.81.43.6-1.01.11.60.9-1.2-1.11.90.20.4
Bone: cortical thickness0.80.92.3-0.70.81.40.6-0.9-1.11.50.40.6
Bone: cortical tissue density0.10.20.4-0.40.50.40.60.5-0.40.6-0.2-0.1
Condit. Reinf. active minus inactive responses2.62.95.8-1.91.81.62.12.4-1.61.01.21.3
Condit. Reinf. active-inactive response ratio5.66.09.6-2.92.82.53.12.5-2.62.11.31.6
Condit. Reinf. active responses0.91.14.5-0.80.80.61.12.1-0.80.10.90.9
Condit. Reinf. inactive responses1.21.42.71.6-1.5-1.3-1.6-0.41.2-1.40.0-0.1
Incentive salience index mean1.41.72.6-1.51.41.41.61.5-1.30.80.90.9
Condit. Reinf. lever presses0.00.10.2-0.00.00.20.1-0.1-0.0-0.40.40.2
Condit. Reinf. active minus inactive responses0.20.32.10.1-0.00.2-0.1-1.4-0.10.3-0.00.1
Condit. Reinf. active-inactive response ratio0.30.31.8-0.10.20.20.3-1.3-0.30.5-0.7-0.3
Condit. Reinf. active responses0.30.41.2-0.40.40.70.2-1.1-0.50.80.30.3
Condit. Reinf. inactive responses0.60.81.6-1.00.91.10.70.6-0.81.01.30.8
Condit. Reinf. lever presses0.30.41.5-0.30.40.70.1-1.2-0.30.90.1-0.2
Condit. Reinf. lever reinforcers received0.20.31.4-0.20.30.60.1-1.2-0.30.80.20.2
Conditioned reinforcement - actives0.40.81.90.4-0.5-0.9-0.21.30.5-1.40.61.1
Conditioned reinforcement - inactives0.40.61.21.0-1.0-1.0-0.80.30.7-1.1-0.10.2
Conditioned locomotion2.43.25.11.9-2.0-2.2-2.1-1.12.2-1.8-0.8-1.1
Patch foraging indifference point 0 sec0.61.12.00.8-1.0-1.1-1.00.11.4-1.0-1.0-1.3
Patch foraging indifference point AUC0.30.40.8-0.70.70.80.5-0.6-0.50.90.7-0.6
Delay disc. indifference point, 0s delay1.71.83.01.4-1.5-1.5-1.7-0.81.7-1.3-0.9-0.8
Delay disc. indifference point, 16s delay0.20.20.7-0.60.50.20.40.8-0.20.50.3-0.0
Delay disc. indifference point, 2s delay2.22.54.01.8-1.8-1.8-2.0-1.01.8-1.7-0.9-0.5
Delay disc. indifference point, 24s delay0.70.81.21.0-1.1-0.9-1.1-0.40.9-0.8-0.8-0.6
Delay disc. indifference point, 4s delay0.20.21.00.3-0.3-0.4-0.3-0.10.30.2-1.0-0.8
Delay disc. indifference point, 8s delay0.60.73.5-0.60.60.20.51.9-0.50.40.81.0
Indifference point function ln k0.50.93.6-1.00.90.61.01.9-0.60.20.30.7
Indifference point function log k0.50.93.6-1.00.90.61.01.9-0.60.20.30.7
Patch foraging total patch changes 0 sec0.40.71.60.5-0.7-0.9-0.70.21.2-0.8-0.9-1.3
Patch foraging total patch changes 12 sec0.10.20.9-0.10.00.2-0.0-0.30.20.3-0.6-0.9
Patch foraging total patch changes 18 sec0.20.41.40.2-0.3-0.3-0.30.20.8-0.5-0.7-1.2
Patch foraging total patch changes 24 sec0.10.20.7-0.20.20.10.20.80.1-0.50.80.3
Patch foraging total patch changes 6 sec0.81.15.00.1-0.3-0.1-0.4-1.30.80.3-1.6-2.2
Patch foraging time to switch 0 sec0.71.42.61.6-1.4-1.4-1.3-0.51.0-1.4-1.00.1
Patch foraging water rate 0 sec0.30.61.2-1.10.90.90.8-0.2-0.61.00.4-0.4
Patch foraging water rate 12 sec1.63.34.7-2.22.12.02.21.3-2.01.51.51.4
Patch foraging water rate 18 sec0.91.42.3-1.51.41.51.4-0.5-1.11.5-0.3-0.4
Patch foraging water rate 24 sec1.31.83.8-1.91.71.51.81.0-1.21.40.3-0.2
Patch foraging water rate 6 sec6.18.914.2-3.63.63.23.82.4-3.33.11.31.3
Seeking ratio, delayed vs. immediate footshock3.03.65.82.2-2.3-1.9-2.4-1.52.0-1.6-1.3-1.6
Distance traveled before self-admin0.40.52.40.6-0.6-0.4-0.5-0.70.3-1.60.70.3
Distance traveled after self-admin0.10.10.60.3-0.3-0.2-0.10.20.2-0.80.1-0.2
Extensor digitorum longus weight4.216.722.8-3.94.34.84.01.2-4.83.74.34.6
Bone: elastic displacement0.60.71.4-0.80.91.20.8-0.1-0.90.60.90.8
Bone: elastic work1.62.13.9-1.61.62.01.5-0.4-1.71.90.60.7
Bone: endosteal estimation0.10.31.1-0.60.50.60.30.1-0.40.21.00.5
Bone: endosteal perimeter0.30.62.6-0.70.60.70.50.4-0.6-0.01.60.9
Epididymis fat weight0.72.54.1-2.01.92.01.71.0-1.61.11.80.8
Delta time in closed arm before/after self-admin1.01.02.8-0.80.80.41.01.7-0.70.21.21.2
Delta time in open arm before/after self-admin0.70.72.60.4-0.3-0.2-0.40.90.2-1.11.11.6
Diff in mean of infusions in LGA sessions0.81.04.7-0.0-0.0-0.30.3-0.50.10.7-2.2-1.8
Delay discount exponential model param0.10.10.3-0.30.30.50.4-0.4-0.4-0.10.60.3
Extinction: sum of active levers before priming0.50.51.3-0.50.50.80.6-0.7-0.61.2-1.0-0.5
Active lever presses in extinction session 61.11.12.90.8-0.9-1.2-0.7-0.21.1-0.5-1.7-1.4
Bone: final force0.30.50.9-0.90.81.00.8-0.1-0.70.90.20.0
Bone: final moment0.30.51.0-0.80.81.00.7-0.3-0.71.00.1-0.1
Food consumed during 24 hour testing period1.82.43.3-1.81.81.81.71.3-1.71.80.71.1
Glucose1.72.64.5-2.02.02.11.80.7-1.82.00.80.2
Heart weight1.11.62.3-1.51.41.51.1-0.1-1.31.51.21.2
Delay discount hyperbolic model param0.20.30.5-0.50.50.70.6-0.2-0.60.10.70.4
Intermittent access intake day 1-15 change0.30.71.40.9-0.9-1.0-0.8-0.70.8-1.2-0.4-0.3
Intermittent access intake escalation0.71.51.91.2-1.3-1.3-1.3-1.21.3-1.4-0.9-1.0
Intermittent access intake escalation 21.01.12.51.0-1.0-1.0-0.8-1.60.8-0.7-1.4-1.0
Intermitt. access day 1 inactive lever presses0.20.61.1-0.80.90.80.71.0-0.71.00.60.5
Intermitt. access day 15 inactive lever presses0.61.12.3-1.01.01.20.80.6-1.10.81.51.2
Intermitt. access escalation Index0.10.10.80.0-0.00.1-0.0-0.2-0.30.00.60.9
Intermittent access day 1 total infusions1.52.53.4-1.81.81.81.81.4-1.81.61.30.8
Intermittent access day 15 total infusions0.20.20.5-0.70.60.70.70.0-0.60.40.1-0.2
Intermittent access terminal intake (last 3 days)0.60.81.6-1.21.01.01.30.8-1.00.60.30.2
Intermittent access total infusions1.51.72.9-1.61.51.51.71.2-1.41.10.80.5
Intermittent access day 1 locomotion0.81.01.5-1.21.11.21.10.7-0.90.91.20.3
Intermittent access day 15 total locomotion0.40.71.70.7-0.7-0.6-0.8-0.90.9-1.30.1-1.0
Intermittent access total locomotion0.10.10.3-0.10.10.30.1-0.5-0.1-0.00.4-0.5
Intermittent access standard deviation0.10.10.3-0.40.40.40.5-0.5-0.40.2-0.2-0.1
Left kidney weight1.04.57.5-2.42.42.72.20.5-2.42.31.61.6
Right kidney weight0.94.16.3-2.32.32.52.00.6-2.22.21.81.6
Cocaine induced anxiety0.10.10.3-0.0-0.1-0.2-0.1-0.30.40.0-0.6-0.3
Post-drug Anxiety0.40.40.70.5-0.6-0.7-0.7-0.50.8-0.6-0.6-0.6
Baseline Anxiety0.10.10.2-0.30.30.40.40.2-0.50.30.30.3
Tail length0.10.40.8-0.40.50.80.5-0.4-0.80.90.50.8
Length with tail0.62.74.4-1.81.91.91.80.3-1.92.11.11.1
Length without tail0.30.81.5-1.21.20.91.10.4-0.81.10.50.4
Times rat made contact with spout0.60.72.9-0.20.30.30.3-0.5-0.31.2-1.7-1.0
Lifetime Intake1.41.72.7-1.61.51.31.71.5-1.31.00.90.7
Liver weight, left0.10.10.5-0.30.40.10.40.3-0.1-0.30.70.4
Liver weight, right0.00.10.2-0.30.30.20.3-0.30.0-0.1-0.2-0.5
Locomotor activity0.20.20.9-0.70.50.40.40.3-0.30.9-0.1-0.4
Locomotor testing distance0.50.92.1-1.21.01.00.90.7-0.91.40.30.1
Locomotor testing rearing1.53.07.7-2.01.81.71.90.5-1.72.8-1.0-1.1
Locomotion in novel chamber6.28.010.12.9-3.1-2.7-3.0-3.22.8-1.8-2.7-3.0
Locomotion in novel chamber post-restriction0.00.10.20.4-0.3-0.1-0.2-0.2-0.10.3-0.4-0.2
Fecal boli incidents, locomotor time 10.10.20.9-0.20.1-0.30.21.0-0.1-0.40.40.7
Change in fecal boli incidents, locomotor task0.70.71.4-0.80.91.20.90.2-0.90.90.7-0.3
Time >=10cm from walls, locomotor time 11.21.34.30.5-0.6-0.5-0.6-1.60.90.0-1.5-2.1
Bouts of movement, locomotor time 10.40.41.4-0.10.00.1-0.1-0.90.10.7-1.2-1.0
Total resting periods, locomotor time 10.20.20.6-0.40.30.30.2-0.3-0.20.8-0.7-0.6
Rest time, locomotor task time 10.10.10.80.3-0.2-0.3-0.2-0.2-0.10.10.40.9
Distance moved, locomotor task time 10.10.20.5-0.40.40.70.20.4-0.10.60.0-0.4
Vertical activity count, locomotor time 10.10.20.50.2-0.30.0-0.5-0.20.6-0.2-0.4-0.7
Time >=10cm from walls, locomotor time 21.31.94.1-1.31.31.41.31.3-1.30.22.01.5
Bouts of movement, locomotor time 20.71.11.51.1-1.2-1.1-1.2-0.91.1-1.0-0.9-1.0
Total resting periods, locomotor time 20.71.21.71.2-1.3-1.1-1.3-0.91.2-1.0-0.9-1.0
Rest time, locomotor task time 20.70.91.81.2-1.1-0.8-1.3-1.30.9-0.4-0.3-0.5
Distance moved, locomotor task time 20.10.10.9-0.20.20.10.21.00.0-0.20.30.4
Vertical activity count, locomotor time 20.10.10.30.2-0.2-0.1-0.30.10.4-0.6-0.10.2
Light reinforcement 11.33.25.3-2.32.12.11.91.8-1.61.61.40.8
Light reinforcement 20.10.20.4-0.30.40.40.20.1-0.40.60.50.4
Bone: marrow area0.10.20.9-0.60.40.50.20.1-0.30.10.90.4
Bone: maximum diameter0.20.40.8-0.80.60.90.2-0.7-0.30.90.80.1
Bone: maximum force0.30.51.0-1.00.80.90.7-0.2-0.50.90.1-0.0
Bone: maximum moment0.30.51.1-0.90.70.90.6-0.5-0.51.1-0.1-0.1
Mean time between licks in bursts0.10.20.7-0.30.20.10.20.20.20.1-0.9-0.7
Mean num. licks in bursts0.40.61.91.0-0.8-0.4-0.9-1.40.30.2-0.6-0.2
Cd content in liver0.30.30.5-0.60.60.70.7-0.2-0.40.7-0.5-0.7
Co content in liver4.75.47.4-2.52.52.32.52.7-2.31.22.42.3
Cu content in liver1.72.05.71.0-1.2-1.1-1.0-0.91.5-1.0-2.4-1.9
Fe content in liver1.82.23.31.8-1.8-1.6-1.8-1.41.5-1.80.0-0.0
K content in liver1.71.62.61.4-1.4-0.9-1.3-1.11.3-1.4-0.6-1.6
Mg content in liver0.40.41.60.4-0.5-0.3-0.4-0.00.6-0.7-0.7-1.3
Mn content in liver0.30.31.20.0-0.00.5-0.1-1.1-0.10.5-0.6-0.6
Na content in liver0.30.30.60.5-0.5-0.6-0.6-0.70.6-0.2-0.4-0.7
Rb content in liver0.30.31.60.4-0.4-0.5-0.20.50.5-1.30.10.3
Se content in liver0.30.30.50.7-0.7-0.4-0.7-0.50.4-0.70.5-0.0
Sr content in liver0.20.20.6-0.20.20.30.2-0.5-0.60.80.50.1
Zn content in liver19.021.242.23.8-4.2-4.0-4.0-3.74.8-3.0-6.1-6.5
Bone: minimum diameter2.34.26.8-2.32.32.62.00.8-2.12.02.01.8
Time in familiar zone, hab. session 10.20.20.60.3-0.3-0.4-0.30.30.4-0.70.30.4
Time in novel zone, hab. session 10.10.10.40.3-0.3-0.1-0.3-0.60.1-0.00.1-0.0
Total zone transitions, hab. session 12.33.310.5-1.61.51.01.63.2-1.30.41.92.3
Total locomotion distance, hab. session 10.30.42.2-0.50.40.00.51.5-0.2-0.10.50.5
Locomotion velocity, hab. session 10.30.41.7-0.70.70.40.81.3-0.50.40.30.3
Time in familiar zone, hab. session 20.50.63.60.3-0.10.4-0.3-1.9-0.30.9-0.2-0.3
Time in novel zone, hab. session 20.50.52.20.1-0.3-0.7-0.11.50.6-1.1-0.0-0.1
Total zone transitions, hab. session 21.72.26.6-1.71.51.01.62.6-1.10.61.21.3
Total locomotion distance, hab. session 20.70.91.5-1.21.10.81.11.1-0.91.10.10.0
Locomotion velocity, hab. session 20.40.61.1-1.00.80.61.01.0-0.70.9-0.0-0.0
Novel to familiar place preference ratio0.10.10.4-0.40.30.30.30.7-0.20.4-0.1-0.3
Novelty place preference0.20.20.4-0.60.40.50.40.7-0.30.6-0.1-0.3
Time in novel zone, NPP test0.20.20.4-0.60.40.50.40.6-0.30.6-0.1-0.4
Total zone transitions, NPP test2.13.15.7-2.01.91.72.02.4-1.71.21.11.4
Total locomotion distance, NPP test0.40.50.9-0.90.80.71.00.6-0.60.8-0.5-0.4
Locomotion velocity, NPP test0.50.81.3-1.11.00.91.10.5-0.81.2-0.6-0.4
Intraocular pressure0.40.50.80.9-0.8-0.7-0.9-0.80.6-0.80.00.6
Delta distance traveled before/after self-admin0.40.41.7-0.70.60.30.71.3-0.30.7-0.1-0.4
Delta ambulatory time before/after self-admin0.40.51.1-0.70.60.30.70.9-0.31.0-0.5-0.7
Parametrial fat weight0.10.30.80.2-0.3-0.4-0.2-0.60.4-0.7-0.4-0.9
Pavlov. Cond. lever latency1.11.42.2-1.21.31.21.30.7-1.51.50.70.9
Pavlov. Cond. magazine entry latency0.20.30.90.00.0-0.10.00.7-0.0-0.71.00.6
Pavlov. Cond. change in total contacts0.30.31.00.3-0.4-0.7-0.31.00.6-0.9-0.2-0.2
Pavlov. Cond. index score0.50.61.10.8-0.8-0.8-0.8-0.50.9-1.0-0.4-0.6
Pavlov. Cond. latency score0.81.01.51.0-1.1-1.0-1.1-0.61.2-1.2-0.6-0.8
Pavlov. Cond. lever contacts0.60.81.10.8-0.9-0.8-0.9-0.81.1-1.1-0.6-0.9
Pavlov. Cond. magazine entry number0.30.41.20.4-0.5-0.2-0.5-1.10.40.3-0.8-0.8
Pavlov. Cond. intertrial magazine entries0.20.20.30.5-0.6-0.5-0.5-0.40.6-0.4-0.3-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.50.70.7-0.7-0.7-0.7-0.40.8-0.8-0.5-0.8
Pavlov. Cond. response bias0.10.20.90.2-0.2-0.3-0.10.50.3-0.90.40.3
Pavlov. Cond. lever latency1.01.42.11.5-1.4-1.4-1.3-0.41.1-1.4-0.8-0.8
Pavlov. Cond. magazine entry latency0.10.10.20.3-0.4-0.5-0.4-0.20.3-0.20.10.0
Pavlov. Cond. change in total contacts0.10.20.4-0.50.40.40.4-0.3-0.20.6-0.3-0.3
Pavlov. Cond. index score0.10.10.70.1-0.1-0.1-0.2-0.90.20.20.00.0
Pavlov. Cond. latency score0.20.20.70.4-0.4-0.5-0.5-0.80.5-0.1-0.4-0.3
Pavlov. Cond. lever contacts1.01.42.0-1.41.41.41.20.1-1.21.41.01.0
Pavlov. Cond. magazine entry number0.10.10.4-0.30.40.50.40.6-0.40.10.0-0.0
Pavlov. Cond. intertrial magazine entries0.20.31.0-0.30.30.80.1-1.0-0.40.8-0.1-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.90.2-0.2-0.2-0.3-0.90.30.1-0.1-0.0
Pavlov. Cond. response bias1.21.62.0-1.41.41.41.20.3-1.31.31.41.4
Time in closed arm before self-admin0.10.10.50.0-0.1-0.4-0.00.10.3-0.0-0.5-0.7
Time in closed arm after self-admin0.40.41.7-0.0-0.2-0.50.10.10.40.2-1.1-1.3
Time in open arm before self-admin0.91.03.4-0.80.91.20.8-0.7-1.11.8-0.3-0.4
Time in open arm after self-admin0.30.31.60.10.00.2-0.20.4-0.2-0.30.71.3
Bone: periosteal estimation0.71.52.8-1.41.31.71.0-0.3-1.21.41.31.0
Bone: periosteal perimeter0.81.43.4-1.21.11.50.80.1-1.10.91.81.4
Bone: post-yield work0.71.02.00.7-0.9-1.3-1.00.11.4-1.4-0.3-0.7
Progressive ratio test 1 active lever presses4.04.97.0-2.42.42.22.52.6-2.31.81.91.6
Progressive ratio test 1 breakpoint3.84.66.6-2.42.32.12.52.6-2.21.81.71.4
Progressive ratio test 1 inactive lever presses0.40.61.0-0.70.70.80.70.9-1.01.00.70.5
Progressive ratio test 2 active lever presses2.02.43.3-1.51.61.61.81.1-1.81.21.41.6
Progressive ratio test 2 breakpoint1.82.02.9-1.51.51.61.71.0-1.71.21.21.4
Progressive ratio test 2 inactive lever presses0.20.41.5-0.10.20.20.40.8-0.4-0.20.91.2
Incentive Sensitization - Responses0.70.92.41.2-1.1-1.0-0.9-0.90.8-1.5-0.20.2
Incentive Sensitization - Breakpoint0.70.92.01.1-1.0-0.9-0.9-1.10.7-1.4-0.20.2
Sum of active levers in priming session hrs 5-61.91.87.00.8-0.7-0.5-0.5-2.00.40.4-2.7-1.8
Progressive ratio0.10.20.5-0.00.10.5-0.1-0.7-0.40.30.70.5
Food seeking constrained by brief footshock1.21.42.3-1.41.51.51.5-0.2-1.41.50.10.2
Seeking ratio, punishment vs. effort0.30.50.9-0.80.70.41.00.8-0.50.7-0.8-0.4
Retroperitoneal fat weight0.41.73.1-1.51.51.81.3-0.4-1.51.51.00.1
Reaction time number correct0.20.41.0-0.70.70.70.70.1-0.81.00.20.3
Reaction time mean minus median0.51.32.71.6-1.4-1.3-1.4-1.01.0-0.9-0.10.3
Reaction time mean minus median AUC0.51.22.51.6-1.4-1.2-1.3-1.10.9-0.7-0.50.0
Reaction time num false alarms0.60.92.80.2-0.2-0.4-0.41.70.3-0.91.41.5
Reaction time num false alarms AUC0.81.23.9-0.10.0-0.1-0.11.6-0.1-0.81.92.0
Reaction time trials correct on left0.20.41.0-0.70.70.70.70.1-0.81.00.20.3
Reaction time trials on left0.20.30.8-0.60.60.60.6-0.0-0.70.90.10.3
Reaction time mean0.20.41.00.9-0.7-0.4-0.7-1.00.20.30.20.4
Reaction time mean AUC0.20.30.50.7-0.4-0.2-0.5-0.7-0.10.40.50.6
Median of all reaction times0.20.20.80.2-0.00.2-0.1-0.7-0.40.90.50.5
Reaction time omissions2.13.05.12.3-2.1-2.0-2.2-1.61.7-1.4-0.8-0.1
Reaction time false alarm rate0.50.71.60.4-0.5-0.6-0.61.10.5-1.11.21.3
Reaction time premature initiation rate1.72.36.3-1.41.51.51.11.4-1.20.52.51.8
Reaction time premature initiations1.83.26.8-1.71.81.81.51.4-1.61.02.62.2
Std. dev. reaction times1.32.34.62.2-1.9-1.7-1.9-1.41.5-1.3-0.5-0.1
Reaction time trials completed0.20.30.8-0.60.60.60.6-0.0-0.70.90.10.3
Reaction time trials AUC0.20.41.0-0.70.70.70.70.0-0.81.00.20.3
Run reversals in cocaine runway, females0.10.10.4-0.10.10.20.20.1-0.20.5-0.7-0.5
Run reversals in cocaine runway, males1.01.12.3-1.01.00.91.21.0-1.31.5-0.40.1
Latency to leave start box in cocaine runway0.20.31.30.2-0.3-0.3-0.40.10.6-0.4-0.5-1.1
Latency to leave start box in cocaine runway, F0.10.10.3-0.1-0.0-0.3-0.10.60.4-0.6-0.0-0.4
Latency to leave start box in cocaine runway, M0.90.82.90.6-0.7-0.5-0.7-1.00.70.0-1.1-1.7
Std. dev. time between licks in bursts0.50.73.3-0.90.60.20.61.80.2-0.3-0.6-0.8
Total sessions with >9 infusions1.31.67.2-1.31.10.71.22.7-0.70.21.10.7
Short access day 1 total inactive lever presses0.40.61.9-0.90.80.70.91.4-0.50.40.2-0.2
Short access day 10 total inactive lever presses0.61.52.51.4-1.4-1.4-1.6-0.11.5-1.4-0.7-0.6
Short access day 1 total infusions0.60.84.5-0.60.4-0.00.62.1-0.0-0.80.70.6
Short access day 10 total infusions1.41.84.9-1.51.31.11.52.2-1.30.90.90.7
Short access total infusions1.62.06.4-1.61.41.01.62.5-1.20.91.00.8
Short access day 1 locomotion0.50.63.2-0.90.70.20.81.8-0.0-0.20.1-0.1
Short access day 10 total locomotion0.10.20.7-0.10.1-0.00.10.20.20.4-0.8-0.8
Short access total locomotion0.20.21.0-0.30.1-0.00.10.70.30.1-0.2-1.0
One hour access (0.3 mA shock)0.00.10.2-0.10.10.30.2-0.5-0.10.30.1-0.1
Compulsive drug intake0.20.31.70.4-0.30.2-0.5-1.30.10.2-0.1-0.4
One hour access (shock baseline)0.30.40.8-0.70.60.60.90.7-0.80.40.50.5
Social response proportion0.91.02.21.2-1.2-0.9-1.3-0.21.0-1.50.1-0.2
Social responses0.30.41.60.1-0.20.2-0.4-1.20.30.2-0.7-1.3
Social time2.43.24.22.0-2.0-1.8-2.1-2.01.9-1.7-1.1-1.5
Soleus weight0.92.74.9-1.41.61.81.50.9-1.80.92.22.0
Bone: stiffness0.60.92.3-1.31.11.21.00.1-0.91.50.20.1
Tibialis anterior weight5.619.027.2-4.24.75.24.30.9-5.24.64.24.4
Time to tail flick, vehicle, before self-admin0.70.71.41.0-1.0-0.9-1.00.21.0-1.20.20.3
Time to tail flick, vehicle, after self-admin1.11.43.11.3-1.3-1.1-1.5-1.21.2-1.80.30.3
Time to tail flick, test, before self-admin1.31.32.51.4-1.4-1.1-1.6-1.21.4-1.0-0.3-0.4
Time to tail flick, test, after self-admin0.10.10.30.3-0.3-0.4-0.4-0.20.5-0.4-0.2-0.2
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.50.40.30.3-0.0-0.2-0.30.40.1
Delta time to tail flick, test, before/after SA0.70.71.6-1.11.10.81.30.8-1.00.50.20.4
Tibia length0.61.53.1-0.91.11.60.8-0.9-1.41.81.11.2
Ambulatory time before self-admin0.40.62.80.7-0.7-0.4-0.6-0.40.4-1.70.60.3
Ambulatory time after self-admin0.60.72.40.8-0.8-0.9-0.70.30.9-1.6-0.0-0.3
Bone: tissue strength0.40.41.0-1.00.80.70.8-0.0-0.50.9-0.2-0.4
Total heroin consumption0.30.41.80.4-0.4-0.3-0.4-1.30.40.3-0.9-0.6
Bone: trabecular number1.01.72.71.6-1.6-1.6-1.6-1.01.5-1.2-0.6-0.4
Bone: trabecular spacing0.40.61.3-0.40.50.70.4-0.9-0.51.0-0.9-1.1
Bone: trabecular thickness0.20.20.8-0.10.20.10.10.7-0.20.10.70.9
Bone: trabecular tissue density0.30.41.1-0.30.40.20.51.1-0.60.50.70.9
Water consumed over 24 hours0.30.40.9-0.70.70.60.70.4-0.61.0-0.30.3
Number of responses in last shaping day2.22.56.7-1.21.20.91.22.6-1.1-0.42.22.1