Hub : Genes

Mrps28

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Mrps28 0.37 0.17 4.5e-05 0.16 0.11 0.17 0.01 1.5e-04 1.2e-03 6.5e-05 1.5e-01
2 PL gene expression Mrps28 0.11 0.08 5.5e-08 0.05 0.05 0.05 0.05 3.3e-06 3.5e-06 4.2e-06 5.3e-06
3 Brain mRNA stability Mrps28 0.09 0.06 1.7e-05 0.01 0.02 0.01 0.01 2.4e-02 4.8e-03 2.7e-02 1.4e-02
4 Liver intron excision ratio chr2_92820902_92855850 0.15 0.09 2.6e-11 0.08 0.09 0.09 0.09 1.3e-09 3.5e-10 3.2e-10 4.2e-10
5 Eye mRNA stability Mrps28 0.34 0.19 2.1e-03 0.24 0.08 0.22 0.24 1.4e-04 2.3e-02 2.9e-04 1.2e-04
6 Adipose mRNA stability Mrps28 0.37 0.18 0.0e+00 0.12 0.19 0.2 0.2 1.1e-12 4.8e-21 5.8e-22 2.3e-21
7 Adipose intron excision ratio chr2_92852680_92855850 0.15 0.09 4.8e-11 0.09 0.09 0.09 0.1 1.5e-10 4.1e-10 1.6e-10 1.2e-10
8 Adipose gene expression Mrps28 0.07 0.05 5.4e-06 0.03 0.04 0.04 0.03 1.0e-04 6.5e-05 6.6e-05 1.1e-04
9 Liver gene expression Mrps28 0.16 0.1 4.0e-13 0.07 0.09 0.09 0.08 6.3e-08 6.3e-10 1.1e-09 1.3e-09
10 Adipose intron excision ratio chr2_92820902_92855850 0.19 0.1 1.7e-14 0.11 0.12 0.12 0.12 1.5e-12 7.8e-13 2.5e-13 1.0e-12
11 Liver mRNA stability Mrps28 0.37 0.29 1.9e-15 0.11 0.12 0.1 0.1 7.3e-12 5.6e-13 1.5e-11 1.0e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.91.62.51.21.0-1.60.4-1.51.50.7-1.6-1.51.0-1.2
Area under the delay curve1.11.11.9-0.7-1.01.2-0.31.4-1.2-0.71.31.3-0.91.1
BMI with tail2.06.518.6-4.3-4.03.63.22.30.12.01.00.51.3-0.7
BMI without tail4.28.624.8-4.7-5.04.42.63.5-1.21.61.81.40.80.0
Body weight0.83.59.6-3.1-2.82.42.71.30.71.70.3-0.01.3-0.8
Weight adjusted by age0.20.20.40.20.1-0.5-0.1-0.4-0.10.3-0.6-0.60.4-0.6
Bone surface1.72.95.10.70.8-1.41.3-2.02.31.6-2.1-2.11.8-1.9
Bone volume1.93.25.31.00.9-1.71.1-2.02.21.5-2.3-2.31.8-2.0
Breakpoint value in progressive ratio session0.10.20.6-0.8-0.50.60.50.20.10.40.10.10.3-0.1
Number of licking bursts0.00.00.1-0.1-0.20.2-0.00.2-0.1-0.00.20.2-0.10.1
Context. condit. distance diff. score0.40.50.9-0.3-0.10.6-0.40.5-0.6-0.81.01.0-0.80.9
Locomotion velocity, session 10.30.30.7-0.8-0.80.80.40.7-0.3-0.10.50.5-0.20.3
Locomotion distance, session 10.40.51.5-1.0-0.70.51.20.00.80.6-0.2-0.30.6-0.5
Locomotion velocity, session 20.80.92.6-1.6-1.51.41.11.2-0.10.50.60.40.2-0.1
Locomotion distance, session 21.31.84.4-1.0-0.80.22.1-0.41.71.7-1.1-1.31.6-1.6
Locomotion velocity, session 30.50.61.30.00.10.2-0.90.6-1.1-1.00.80.9-0.90.9
Locomotion distance, session 30.30.30.60.10.2-0.50.5-0.50.70.6-0.8-0.80.7-0.7
Stereotopy head waving bouts, day 30.10.10.20.40.3-0.40.1-0.50.30.1-0.4-0.40.2-0.2
Stereotopy head waving duration, day 30.50.60.9-0.6-0.70.8-0.30.9-0.9-0.50.90.9-0.70.8
Locomotion velocity, session 78.79.615.72.02.2-3.41.6-3.83.82.1-4.0-3.82.8-3.2
Locomotion distance, session 73.34.27.92.12.4-2.80.2-2.82.30.5-2.4-2.21.1-1.5
Stereotopy head waving bouts, day 70.40.51.6-1.1-1.31.00.70.7-0.30.50.30.20.3-0.1
Stereotopy head waving duration, day 70.91.12.3-1.3-1.51.50.21.3-1.1-0.21.11.0-0.40.7
Locomotion velocity, session 81.21.53.6-1.9-1.91.81.11.7-0.40.40.90.80.10.2
Locomotion distance, session 80.30.51.3-1.1-0.90.81.10.40.50.60.1-0.00.5-0.4
Degree of sensitization distance0.60.61.20.91.0-1.1-0.1-1.10.80.2-0.9-0.80.4-0.6
Degree of sensitization stereotypy1.41.53.5-1.7-1.91.90.51.5-1.10.11.21.0-0.30.6
Conditioned locomotion0.30.40.70.30.1-0.50.6-0.40.70.7-0.8-0.80.8-0.9
Cocaine response after cond. corrected0.70.82.71.61.5-1.4-0.9-0.80.3-0.7-0.4-0.3-0.50.1
Cocaine response after cond. not corrected1.61.75.32.32.0-2.1-1.3-1.30.3-0.7-0.9-0.7-0.4-0.0
Cocaine response before conditioning0.40.51.20.80.6-1.0-0.3-1.10.20.3-0.9-0.80.5-0.5
Saline control response1.21.52.90.4-0.0-1.00.8-1.11.11.4-1.7-1.71.6-1.6
Bone: connectivity density1.11.73.11.21.4-1.70.2-1.71.50.6-1.6-1.51.0-1.2
Bone: cortical apparent density0.30.41.0-0.8-1.00.80.20.8-0.6-0.20.60.5-0.30.4
Bone: cortical area0.50.81.9-1.3-1.41.21.40.60.40.90.1-0.00.7-0.4
Bone: cortical porosity0.00.10.1-0.3-0.20.20.3-0.00.20.3-0.1-0.20.2-0.2
Bone: cortical porosity0.00.00.1-0.2-0.10.10.3-0.10.20.2-0.2-0.20.2-0.2
Bone: cortical thickness0.40.72.0-1.3-1.41.20.90.8-0.10.60.40.20.3-0.1
Bone: cortical thickness2.63.06.9-2.4-2.62.60.72.3-1.50.11.71.5-0.40.8
Bone: cortical tissue density0.30.40.9-0.8-1.00.70.10.8-0.6-0.20.60.6-0.30.4
Condit. Reinf. active minus inactive responses4.14.69.2-2.1-2.00.83.00.11.63.0-1.7-1.92.9-2.6
Condit. Reinf. active-inactive response ratio5.76.112.5-2.3-2.20.83.40.11.73.5-2.0-2.33.3-3.1
Condit. Reinf. active responses3.74.59.1-2.0-1.90.83.0-0.01.73.0-1.7-1.92.8-2.5
Condit. Reinf. inactive responses0.10.20.5-0.7-0.50.70.50.20.10.20.30.20.10.0
Incentive salience index mean4.04.910.7-2.1-1.80.93.3-0.12.03.0-1.7-1.92.8-2.6
Condit. Reinf. lever presses1.72.36.4-1.8-1.30.92.5-0.21.71.9-0.8-1.01.7-1.5
Condit. Reinf. active minus inactive responses2.42.95.30.70.7-1.51.3-2.02.31.5-2.1-2.11.8-1.9
Condit. Reinf. active-inactive response ratio1.71.83.1-0.2-0.2-0.51.6-0.91.81.6-1.5-1.61.6-1.7
Condit. Reinf. active responses3.85.38.61.61.5-2.41.2-2.92.91.7-2.9-2.82.1-2.4
Condit. Reinf. inactive responses1.31.63.21.31.2-1.50.2-1.81.30.7-1.5-1.50.9-1.1
Condit. Reinf. lever presses1.01.42.50.90.9-1.20.5-1.61.40.9-1.5-1.41.1-1.2
Condit. Reinf. lever reinforcers received3.34.77.61.61.5-2.31.0-2.82.71.5-2.7-2.72.0-2.2
Conditioned reinforcement - actives2.32.34.51.61.7-2.00.0-2.11.70.5-1.8-1.70.9-1.3
Conditioned reinforcement - inactives0.91.02.31.21.2-1.5-0.1-1.31.10.0-1.1-1.00.3-0.6
Conditioned locomotion0.20.30.60.70.2-0.70.1-0.80.40.1-0.7-0.70.2-0.4
Patch foraging indifference point 0 sec0.50.92.21.41.5-1.1-1.3-0.5-0.3-1.1-0.00.1-0.80.4
Patch foraging indifference point AUC0.00.00.20.40.2-0.4-0.2-0.10.00.0-0.1-0.10.10.0
Delay disc. indifference point, 0s delay0.10.10.30.10.10.2-0.30.3-0.3-0.40.50.5-0.50.5
Delay disc. indifference point, 16s delay0.60.61.4-0.7-0.91.0-0.11.2-1.0-0.30.90.8-0.50.6
Delay disc. indifference point, 2s delay0.70.82.3-1.1-0.80.61.5-0.00.81.1-0.5-0.61.0-0.8
Delay disc. indifference point, 24s delay0.60.61.00.2-0.20.3-0.80.5-1.0-0.90.90.9-1.01.0
Delay disc. indifference point, 4s delay2.52.65.6-1.8-1.92.20.12.4-1.6-0.51.91.7-0.91.2
Delay disc. indifference point, 8s delay1.21.22.10.4-0.10.3-1.10.9-1.3-1.41.21.3-1.41.4
Indifference point function ln k1.11.52.7-0.9-1.21.4-0.51.6-1.6-0.81.51.4-1.01.1
Indifference point function log k1.11.52.7-0.9-1.21.4-0.51.6-1.6-0.81.51.4-1.01.1
Patch foraging total patch changes 0 sec0.60.92.21.21.2-0.8-1.5-0.1-0.7-1.20.30.5-1.10.7
Patch foraging total patch changes 12 sec0.91.22.61.51.6-1.0-1.5-0.6-0.3-1.30.40.6-1.11.0
Patch foraging total patch changes 18 sec0.20.20.7-0.1-0.10.3-0.50.5-0.8-0.30.60.6-0.30.5
Patch foraging total patch changes 24 sec0.20.30.70.70.9-0.4-0.7-0.1-0.1-0.70.30.4-0.60.7
Patch foraging total patch changes 6 sec0.20.30.70.60.8-0.4-0.9-0.1-0.4-0.50.20.3-0.40.5
Patch foraging time to switch 0 sec1.52.36.3-1.7-1.30.92.5-0.11.51.9-0.8-1.11.8-1.5
Patch foraging water rate 0 sec0.60.92.30.40.40.0-1.50.7-1.4-1.20.80.9-1.21.0
Patch foraging water rate 12 sec0.20.31.01.00.7-0.7-0.7-0.3-0.0-0.4-0.2-0.1-0.30.0
Patch foraging water rate 18 sec0.10.20.50.10.2-0.40.1-0.20.30.4-0.7-0.70.5-0.7
Patch foraging water rate 24 sec0.40.61.40.0-0.10.3-1.00.9-1.2-0.90.80.8-0.90.8
Patch foraging water rate 6 sec0.30.41.21.00.6-0.6-1.1-0.2-0.5-0.70.10.2-0.60.5
Seeking ratio, delayed vs. immediate footshock2.12.57.12.52.7-2.2-1.7-1.70.4-1.3-0.6-0.3-0.80.4
Distance traveled before self-admin1.51.63.1-1.4-1.51.70.11.7-1.2-0.41.51.4-0.81.0
Distance traveled after self-admin1.21.33.1-0.9-1.01.3-0.51.7-1.4-0.61.41.3-0.91.0
Extensor digitorum longus weight5.120.056.0-7.5-7.06.94.15.2-1.62.33.02.31.00.1
Bone: elastic displacement0.80.91.4-0.00.2-0.50.8-0.91.11.1-1.1-1.21.2-1.2
Bone: elastic work0.40.50.9-0.2-0.1-0.20.8-0.60.90.9-0.8-0.90.9-0.9
Bone: endosteal estimation1.43.16.2-0.9-0.70.22.5-0.92.22.4-1.6-1.82.3-2.1
Bone: endosteal perimeter0.51.02.80.00.4-0.41.2-1.01.71.0-1.0-1.01.0-1.0
Epididymis fat weight0.40.92.10.50.3-0.0-1.00.3-0.8-1.51.01.1-1.41.3
Delta time in closed arm before/after self-admin1.61.52.8-1.2-0.91.6-0.11.6-1.0-0.71.71.6-0.91.3
Delta time in open arm before/after self-admin0.20.20.40.60.6-0.7-0.2-0.50.2-0.2-0.4-0.4-0.1-0.2
Diff in mean of infusions in LGA sessions0.91.02.4-1.5-1.31.31.60.50.61.10.0-0.10.9-0.6
Delay discount exponential model param0.91.01.60.50.8-1.00.4-1.21.20.8-1.3-1.21.0-1.1
Extinction: sum of active levers before priming0.10.10.2-0.4-0.40.4-0.10.5-0.4-0.10.30.3-0.20.2
Active lever presses in extinction session 60.00.00.10.30.2-0.2-0.30.0-0.0-0.1-0.0-0.0-0.10.0
Bone: final force0.71.22.8-1.6-1.61.21.70.60.51.2-0.1-0.31.0-0.7
Bone: final moment0.61.02.4-1.4-1.41.11.60.50.61.1-0.1-0.30.9-0.7
Food consumed during 24 hour testing period1.01.22.9-1.6-1.41.70.31.2-1.0-0.21.31.1-0.40.8
Glucose1.21.93.5-1.6-1.91.80.11.8-1.5-0.41.51.4-0.71.0
Heart weight0.50.61.51.21.1-0.8-1.0-0.5-0.2-1.00.20.3-0.80.7
Delay discount hyperbolic model param1.01.11.80.71.0-1.20.1-1.31.10.7-1.3-1.20.9-1.1
Intermittent access intake day 1-15 change1.21.23.61.81.9-1.4-1.3-0.80.0-1.1-0.10.1-0.80.6
Intermittent access intake escalation0.80.82.61.51.6-1.2-1.1-0.70.0-0.7-0.20.0-0.50.4
Intermittent access intake escalation 21.91.95.52.22.3-2.0-1.2-1.70.7-0.6-0.9-0.6-0.30.0
Intermitt. access day 1 inactive lever presses1.01.03.1-0.1-0.50.5-1.11.2-1.8-0.81.11.1-1.01.1
Intermitt. access day 15 inactive lever presses2.42.67.32.11.7-1.4-2.7-0.4-1.6-2.00.50.8-1.81.4
Intermitt. access escalation Index0.50.41.1-0.1-0.10.5-0.80.6-1.1-0.50.80.8-0.60.7
Intermittent access day 1 total infusions2.32.66.32.11.8-2.5-0.5-2.01.30.1-2.0-1.80.6-1.2
Intermittent access day 15 total infusions3.43.89.73.02.8-3.1-1.1-2.41.3-0.4-1.9-1.60.2-0.8
Intermittent access terminal intake (last 3 days)3.53.89.63.13.0-3.0-1.3-2.31.2-0.6-1.7-1.4-0.1-0.5
Intermittent access total infusions2.73.07.82.82.5-2.7-1.0-2.01.2-0.6-1.5-1.3-0.1-0.5
Intermittent access day 1 locomotion0.40.41.00.90.7-1.0-0.3-0.70.4-0.2-0.6-0.6-0.0-0.3
Intermittent access day 15 total locomotion0.60.71.30.80.7-1.10.1-1.10.80.4-1.1-1.00.5-0.8
Intermittent access total locomotion0.70.82.11.41.2-1.5-0.6-1.10.6-0.4-0.8-0.6-0.1-0.2
Intermittent access standard deviation1.71.84.22.12.0-1.4-1.9-0.4-0.5-1.60.20.5-1.31.0
Left kidney weight0.61.73.51.11.2-0.3-1.90.2-1.1-1.81.01.2-1.71.6
Right kidney weight1.33.67.11.21.2-0.1-2.40.6-1.7-2.71.92.1-2.62.5
Cocaine induced anxiety0.30.40.60.30.10.1-0.70.4-0.8-0.70.60.7-0.70.8
Post-drug Anxiety0.40.40.9-0.8-0.90.90.20.9-0.80.10.60.5-0.10.3
Baseline Anxiety0.30.30.5-0.3-0.2-0.20.6-0.30.30.7-0.6-0.70.7-0.7
Tail length0.30.82.7-1.1-1.61.20.61.4-0.70.30.60.5-0.00.2
Length with tail0.10.20.50.20.4-0.50.3-0.50.70.3-0.5-0.50.4-0.4
Length without tail1.22.65.11.72.3-2.20.0-2.21.70.3-1.8-1.60.7-1.1
Times rat made contact with spout0.20.20.4-0.2-0.30.4-0.30.5-0.6-0.40.60.6-0.50.6
Lifetime Intake2.93.38.93.02.7-2.9-1.3-2.01.1-0.8-1.5-1.2-0.2-0.4
Liver weight, left0.81.34.0-2.0-1.81.71.31.2-0.30.90.50.30.6-0.3
Liver weight, right0.40.61.10.20.10.2-0.90.4-1.0-1.00.90.9-1.01.0
Locomotor activity0.61.02.1-1.3-1.31.40.41.4-0.6-0.21.11.0-0.50.6
Locomotor testing distance0.20.30.8-0.7-0.80.80.10.9-0.5-0.10.60.5-0.30.3
Locomotor testing rearing0.50.71.71.00.8-0.5-1.3-0.2-0.6-1.10.50.6-1.01.0
Locomotion in novel chamber0.81.02.5-1.6-1.61.31.11.00.01.10.2-0.00.8-0.5
Locomotion in novel chamber post-restriction0.60.71.4-0.20.00.5-1.00.5-1.2-0.91.01.1-0.91.1
Fecal boli incidents, locomotor time 10.20.20.30.40.3-0.50.1-0.50.30.3-0.6-0.50.4-0.5
Change in fecal boli incidents, locomotor task0.40.40.90.51.0-0.4-0.7-0.4-0.0-0.90.30.4-0.70.7
Time >=10cm from walls, locomotor time 10.10.10.3-0.00.2-0.30.0-0.60.20.3-0.5-0.50.4-0.4
Bouts of movement, locomotor time 13.53.87.60.70.30.4-2.61.3-2.8-2.32.02.2-2.32.3
Total resting periods, locomotor time 11.92.14.50.80.5-0.0-2.10.8-2.0-1.81.31.4-1.71.6
Rest time, locomotor task time 11.31.52.70.20.30.2-1.50.7-1.5-1.61.31.4-1.61.5
Distance moved, locomotor task time 10.40.40.9-0.7-0.60.50.90.40.61.0-0.3-0.40.8-0.7
Vertical activity count, locomotor time 11.41.43.6-1.3-1.20.91.90.11.21.7-0.6-0.71.4-1.2
Time >=10cm from walls, locomotor time 20.40.40.9-0.6-0.30.10.7-0.40.60.9-0.6-0.70.9-0.8
Bouts of movement, locomotor time 24.54.89.8-0.0-0.41.2-2.41.8-3.1-2.42.62.6-2.62.7
Total resting periods, locomotor time 25.66.012.1-0.1-0.51.4-2.61.9-3.5-2.62.92.9-2.93.0
Rest time, locomotor task time 22.02.34.2-0.5-0.41.0-1.41.1-2.1-1.61.91.9-1.71.9
Distance moved, locomotor task time 20.20.20.4-0.4-0.20.30.60.50.70.5-0.1-0.20.4-0.5
Vertical activity count, locomotor time 22.02.14.8-2.0-2.01.52.21.20.91.7-0.2-0.41.4-1.2
Light reinforcement 10.10.30.50.0-0.30.3-0.10.7-0.4-0.50.60.6-0.60.7
Light reinforcement 21.31.84.5-2.0-2.11.91.02.0-0.80.31.00.8-0.00.2
Bone: marrow area1.43.16.4-1.1-0.80.32.5-0.82.12.4-1.6-1.72.3-2.1
Bone: maximum diameter0.30.51.5-1.1-0.91.21.00.60.30.40.50.40.10.1
Bone: maximum force0.40.71.9-1.2-1.41.11.20.60.20.90.10.00.6-0.4
Bone: maximum moment0.30.51.3-1.1-1.21.01.10.40.30.80.1-0.00.6-0.3
Mean time between licks in bursts1.52.13.30.30.5-0.91.3-1.51.81.5-1.8-1.81.7-1.8
Mean num. licks in bursts0.00.00.1-0.2-0.10.1-0.10.2-0.3-0.20.20.2-0.20.2
Cd content in liver1.01.21.9-0.5-0.51.0-0.61.4-1.3-0.91.41.4-1.11.2
Co content in liver2.22.64.3-0.2-0.31.1-1.41.5-1.8-1.72.02.1-2.02.0
Cu content in liver1.62.05.82.42.4-2.0-1.3-1.60.6-1.0-0.6-0.3-0.70.3
Fe content in liver1.82.13.40.10.2-0.71.5-1.31.81.7-1.7-1.81.8-1.8
K content in liver1.01.02.61.51.6-1.4-0.3-1.41.1-0.4-0.7-0.6-0.1-0.2
Mg content in liver1.61.73.41.21.3-1.50.5-1.71.80.5-1.5-1.40.8-1.1
Mn content in liver0.40.40.80.40.6-0.70.3-0.90.80.4-0.8-0.80.5-0.6
Na content in liver0.20.30.5-0.00.20.2-0.50.2-0.4-0.70.60.6-0.70.7
Rb content in liver0.00.00.10.20.2-0.1-0.10.2-0.1-0.20.10.1-0.20.1
Se content in liver0.20.31.10.81.0-0.6-0.6-0.70.2-0.3-0.1-0.1-0.20.2
Sr content in liver0.20.10.3-0.2-0.1-0.00.4-0.30.40.5-0.4-0.40.5-0.5
Zn content in liver1.01.13.11.71.8-1.4-1.3-1.20.1-0.8-0.3-0.2-0.60.4
Bone: minimum diameter3.15.812.9-1.8-1.50.73.6-0.92.93.2-1.9-2.23.1-2.8
Time in familiar zone, hab. session 11.91.83.60.1-0.30.7-1.51.3-1.9-1.41.51.6-1.61.6
Time in novel zone, hab. session 10.50.41.00.70.8-1.00.0-1.00.70.1-0.8-0.70.3-0.5
Total zone transitions, hab. session 10.40.51.1-0.7-0.80.21.00.30.40.9-0.6-0.70.9-0.8
Total locomotion distance, hab. session 11.01.42.4-0.4-0.3-0.41.5-0.51.41.5-1.4-1.41.5-1.5
Locomotion velocity, hab. session 11.21.73.5-1.0-0.70.11.9-0.21.51.7-1.2-1.41.7-1.6
Time in familiar zone, hab. session 22.42.55.61.31.4-0.6-2.40.4-1.6-2.21.21.4-2.01.8
Time in novel zone, hab. session 21.41.42.7-0.9-1.20.41.6-0.20.91.7-1.0-1.11.5-1.4
Total zone transitions, hab. session 20.20.20.4-0.30.10.3-0.30.5-0.4-0.50.60.6-0.50.5
Total locomotion distance, hab. session 20.20.30.5-0.6-0.10.20.7-0.00.60.7-0.4-0.50.7-0.6
Locomotion velocity, hab. session 20.20.20.5-0.50.10.00.7-0.10.70.6-0.4-0.50.6-0.6
Novel to familiar place preference ratio0.30.30.7-0.9-0.80.80.50.4-0.10.50.20.10.3-0.1
Novelty place preference0.20.20.6-0.7-0.70.80.30.5-0.30.20.40.30.10.1
Time in novel zone, NPP test0.50.51.1-0.9-0.91.10.00.9-0.8-0.10.80.7-0.30.5
Total zone transitions, NPP test0.00.10.2-0.5-0.30.40.30.4-0.0-0.00.20.2-0.00.1
Total locomotion distance, NPP test0.20.30.6-0.6-0.30.20.8-0.00.50.7-0.4-0.50.7-0.6
Locomotion velocity, NPP test0.40.51.0-0.20.1-0.30.8-0.61.00.8-0.8-0.90.9-0.9
Intraocular pressure1.21.65.1-2.3-2.02.01.41.1-0.20.80.80.60.50.0
Delta distance traveled before/after self-admin0.30.30.60.50.6-0.7-0.1-0.40.40.4-0.8-0.80.5-0.7
Delta ambulatory time before/after self-admin0.60.71.71.11.3-1.2-0.6-0.90.50.1-0.9-0.80.3-0.6
Parametrial fat weight0.10.10.2-0.2-0.30.4-0.00.4-0.5-0.20.40.4-0.20.4
Pavlov. Cond. lever latency1.11.44.41.00.4-0.3-2.10.4-1.9-1.30.80.9-1.21.2
Pavlov. Cond. magazine entry latency0.40.51.6-1.0-0.70.71.30.20.70.8-0.2-0.30.7-0.6
Pavlov. Cond. change in total contacts1.71.95.6-2.0-1.61.52.40.51.21.5-0.1-0.31.1-0.9
Pavlov. Cond. index score0.60.82.8-1.2-0.80.81.70.21.10.9-0.1-0.30.7-0.6
Pavlov. Cond. latency score0.60.72.7-1.1-0.60.71.60.11.20.8-0.1-0.30.6-0.6
Pavlov. Cond. lever contacts2.22.56.8-1.0-0.40.22.6-0.82.51.8-1.3-1.41.7-1.7
Pavlov. Cond. magazine entry number0.60.82.21.51.3-1.3-1.1-0.90.1-0.6-0.5-0.3-0.30.1
Pavlov. Cond. intertrial magazine entries1.72.14.52.11.8-2.1-0.7-1.90.90.3-1.6-1.50.6-0.9
Pavlov. Cond. lever-magazine prob. diff.0.60.72.5-1.2-0.80.91.60.31.00.80.0-0.10.6-0.4
Pavlov. Cond. response bias1.11.33.9-1.6-1.21.02.00.41.11.3-0.3-0.51.1-1.0
Pavlov. Cond. lever latency0.60.82.3-1.2-1.21.20.31.5-0.8-0.00.80.7-0.20.4
Pavlov. Cond. magazine entry latency0.10.10.2-0.5-0.20.30.4-0.30.40.30.0-0.00.2-0.2
Pavlov. Cond. change in total contacts1.42.03.8-0.1-0.1-0.51.6-1.51.91.6-1.5-1.61.7-1.6
Pavlov. Cond. index score0.50.71.2-0.00.1-0.30.8-1.11.10.9-0.9-0.91.0-0.9
Pavlov. Cond. latency score0.40.41.20.20.3-0.40.5-1.10.90.6-0.7-0.80.7-0.7
Pavlov. Cond. lever contacts0.70.92.61.01.1-1.10.0-1.61.10.4-1.1-1.00.6-0.7
Pavlov. Cond. magazine entry number0.30.30.80.80.5-0.5-0.90.3-0.6-0.70.20.3-0.60.5
Pavlov. Cond. intertrial magazine entries0.20.20.5-0.3-0.50.10.70.30.40.7-0.4-0.50.6-0.6
Pavlov. Cond. lever-magazine prob. diff.0.50.61.20.20.3-0.50.6-1.11.00.7-0.9-0.90.9-0.8
Pavlov. Cond. response bias0.91.22.40.20.5-0.70.9-1.51.51.0-1.2-1.21.2-1.2
Time in closed arm before self-admin1.01.23.11.81.5-1.7-0.8-1.20.3-0.0-1.1-0.90.3-0.5
Time in closed arm after self-admin0.80.81.7-0.1-0.30.6-0.91.1-1.3-0.61.11.1-0.81.0
Time in open arm before self-admin0.50.51.2-1.1-0.90.71.1-0.00.60.8-0.1-0.20.7-0.4
Time in open arm after self-admin0.30.31.2-1.1-0.90.70.90.40.10.20.10.00.1-0.2
Bone: periosteal estimation1.63.38.2-1.8-1.61.02.9-0.21.92.5-1.1-1.42.2-1.9
Bone: periosteal perimeter0.30.41.3-0.7-0.60.51.20.00.80.8-0.2-0.30.7-0.5
Bone: post-yield work0.71.02.01.41.2-0.7-1.4-0.3-0.7-1.30.50.7-1.21.1
Progressive ratio test 1 active lever presses2.32.45.82.42.0-1.7-2.0-0.4-0.5-2.10.30.5-1.71.2
Progressive ratio test 1 breakpoint2.02.15.42.32.0-1.7-1.8-0.5-0.3-1.90.10.4-1.61.0
Progressive ratio test 1 inactive lever presses0.50.61.30.80.4-0.5-1.00.2-0.8-1.20.50.6-1.00.8
Progressive ratio test 2 active lever presses1.41.53.71.81.8-1.9-0.6-1.71.0-0.4-1.1-0.90.0-0.3
Progressive ratio test 2 breakpoint1.31.53.61.61.7-1.9-0.5-1.71.1-0.2-1.2-1.00.2-0.5
Progressive ratio test 2 inactive lever presses0.70.92.81.71.1-1.4-1.2-1.0-0.0-0.6-0.5-0.4-0.30.1
Incentive Sensitization - Responses2.62.74.91.11.2-1.70.6-2.22.01.2-2.0-2.01.5-1.6
Incentive Sensitization - Breakpoint2.22.24.31.11.2-1.70.5-2.11.91.0-1.8-1.81.3-1.4
Sum of active levers in priming session hrs 5-60.60.61.20.40.5-0.70.6-0.91.10.6-0.9-0.90.7-0.8
Progressive ratio2.42.84.6-0.3-0.20.9-1.51.4-1.8-2.02.12.1-2.12.1
Food seeking constrained by brief footshock2.43.07.5-2.5-2.01.62.70.81.22.1-0.5-0.81.8-1.5
Seeking ratio, punishment vs. effort3.94.88.4-0.8-0.7-0.32.8-1.12.52.9-2.3-2.52.9-2.8
Retroperitoneal fat weight0.10.20.80.40.9-0.4-0.1-0.60.4-0.3-0.1-0.0-0.10.1
Reaction time number correct0.71.02.00.30.0-0.80.5-0.80.71.2-1.4-1.41.3-1.3
Reaction time mean minus median1.72.24.0-0.7-0.61.2-1.31.6-2.0-1.51.81.8-1.71.6
Reaction time mean minus median AUC1.51.93.2-1.3-1.01.4-0.71.6-1.8-1.11.71.6-1.31.3
Reaction time num false alarms1.62.25.60.00.7-1.11.5-1.72.41.2-1.7-1.71.5-1.5
Reaction time num false alarms AUC1.42.04.60.10.9-1.21.2-1.82.21.0-1.7-1.61.3-1.4
Reaction time trials correct on left0.71.02.00.30.0-0.80.5-0.80.71.2-1.4-1.41.3-1.3
Reaction time trials on left0.81.12.20.30.0-0.80.6-0.90.81.2-1.4-1.51.3-1.4
Reaction time mean0.60.92.4-1.5-1.31.40.41.2-0.70.00.90.8-0.20.4
Reaction time mean AUC0.70.92.6-1.6-1.41.50.51.2-0.70.10.90.8-0.10.3
Median of all reaction times0.71.03.2-1.8-1.51.41.10.9-0.10.70.50.30.5-0.2
Reaction time omissions0.20.20.6-0.8-0.70.6-0.10.7-0.5-0.20.50.4-0.30.2
Reaction time false alarm rate0.20.21.2-0.20.6-0.30.6-0.71.1-0.1-0.3-0.20.1-0.1
Reaction time premature initiation rate0.91.22.81.71.6-0.9-1.2-0.7-0.0-1.30.30.5-1.21.1
Reaction time premature initiations0.60.92.81.71.4-1.3-0.9-1.10.2-0.6-0.4-0.2-0.50.3
Std. dev. reaction times1.52.13.3-0.9-0.61.3-1.11.5-1.8-1.31.81.8-1.51.5
Reaction time trials completed0.81.12.20.30.0-0.80.6-0.90.81.2-1.4-1.51.3-1.4
Reaction time trials AUC0.91.32.60.30.0-0.90.7-0.90.91.4-1.6-1.61.4-1.6
Run reversals in cocaine runway, females1.51.43.9-1.7-1.62.00.51.4-0.5-0.01.41.2-0.40.7
Run reversals in cocaine runway, males1.51.54.1-2.0-1.71.61.41.20.01.30.2-0.01.0-0.6
Latency to leave start box in cocaine runway0.20.20.60.80.6-0.60.0-0.50.6-0.2-0.2-0.2-0.10.1
Latency to leave start box in cocaine runway, F0.91.03.11.81.4-1.6-0.7-1.20.5-0.3-0.8-0.70.0-0.2
Latency to leave start box in cocaine runway, M0.30.31.1-0.8-0.80.71.00.40.40.30.20.20.2-0.1
Std. dev. time between licks in bursts0.80.91.70.20.2-0.70.6-1.00.81.1-1.3-1.31.2-1.3
Total sessions with >9 infusions1.51.65.02.22.1-1.9-1.4-1.00.3-1.0-0.6-0.4-0.70.1
Short access day 1 total inactive lever presses1.11.23.82.01.6-1.6-1.3-0.90.0-0.9-0.3-0.1-0.70.4
Short access day 10 total inactive lever presses1.51.73.5-0.3-0.70.8-1.11.4-1.9-1.31.61.6-1.41.5
Short access day 1 total infusions1.41.54.42.12.0-1.6-1.5-0.70.0-1.2-0.2-0.0-0.90.5
Short access day 10 total infusions2.32.57.42.72.3-2.4-2.0-1.3-0.2-1.5-0.7-0.4-1.00.4
Short access total infusions2.83.18.73.02.7-2.8-1.6-1.80.7-1.1-1.2-0.9-0.5-0.2
Short access day 1 locomotion0.80.91.70.40.50.1-1.00.4-0.7-1.31.01.1-1.31.3
Short access day 10 total locomotion0.10.20.5-0.3-0.40.3-0.00.7-0.4-0.30.50.4-0.40.3
Short access total locomotion0.30.30.80.90.6-0.5-0.6-0.2-0.1-0.90.20.3-0.80.5
One hour access (0.3 mA shock)1.82.14.62.12.0-2.1-0.5-1.91.4-0.2-1.4-1.20.2-0.6
Compulsive drug intake1.51.53.6-1.8-1.91.91.51.60.00.90.70.50.4-0.2
One hour access (shock baseline)3.23.89.53.13.0-3.0-1.6-2.41.0-1.0-1.4-1.1-0.4-0.1
Social response proportion0.91.01.9-0.2-0.20.5-1.10.8-1.4-1.21.11.1-1.21.1
Social responses1.62.14.7-0.6-0.71.1-1.21.5-2.2-1.41.71.7-1.61.5
Social time0.71.02.11.41.4-1.5-0.7-1.40.4-0.1-0.9-0.80.1-0.3
Soleus weight0.61.85.0-2.2-1.92.20.91.6-0.70.31.31.1-0.10.5
Bone: stiffness0.10.20.5-0.5-0.70.70.10.6-0.50.00.50.4-0.10.3
Tibialis anterior weight5.117.448.4-7.0-6.55.85.13.9-0.03.71.20.52.6-1.6
Time to tail flick, vehicle, before self-admin0.50.51.20.70.8-0.90.1-1.10.90.3-0.8-0.80.5-0.5
Time to tail flick, vehicle, after self-admin1.11.22.01.31.1-1.40.1-1.21.20.6-1.3-1.20.8-1.0
Time to tail flick, test, before self-admin0.30.31.10.40.5-0.1-1.00.5-0.8-0.60.40.5-0.60.5
Time to tail flick, test, after self-admin0.90.92.51.61.2-1.3-1.5-0.9-0.5-0.7-0.4-0.2-0.50.3
Delta time to tail flick, vehicle, before/after SA0.90.91.81.21.1-1.3-0.0-1.11.00.3-1.2-1.10.6-0.8
Delta time to tail flick, test, before/after SA0.50.40.80.50.1-0.1-0.90.1-0.9-0.90.60.7-0.80.9
Tibia length0.30.82.11.41.0-1.0-1.3-0.1-0.6-1.00.10.2-0.80.7
Ambulatory time before self-admin1.01.02.2-1.0-1.21.30.11.5-1.0-0.31.21.1-0.60.8
Ambulatory time after self-admin0.10.10.6-0.3-0.30.4-0.20.8-0.6-0.10.30.3-0.20.1
Bone: tissue strength0.70.71.51.21.2-1.0-1.2-0.5-0.3-1.10.10.3-0.80.6
Total heroin consumption0.30.30.7-0.10.1-0.20.6-0.60.80.6-0.6-0.70.7-0.7
Bone: trabecular number0.30.51.00.80.7-1.00.1-0.90.80.2-0.8-0.70.4-0.5
Bone: trabecular spacing0.10.10.3-0.5-0.30.50.20.2-0.10.20.20.10.2-0.0
Bone: trabecular thickness0.70.81.71.10.8-1.30.1-1.10.80.4-1.2-1.10.6-0.8
Bone: trabecular tissue density1.31.84.1-0.2-0.80.9-1.21.3-2.0-1.31.61.6-1.41.5
Water consumed over 24 hours0.40.51.0-0.9-1.00.90.10.9-0.80.10.60.5-0.10.3
Number of responses in last shaping day0.30.40.90.3-0.20.2-0.70.6-0.9-0.60.60.6-0.70.6