Macrod1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr1_204254960_204257000 0.08 0.04 5.6e-10 0.09 0.09 0.1 0.1 3.5e-10 2.7e-10 7.2e-11 1.1e-10
2 pVTA intron excision ratio chr1_204254960_204257000 0.09 0.05 6.0e-04 0.1 0.07 0.07 0.08 3.3e-05 6.0e-04 7.4e-04 1.9e-04
3 BLA intron excision ratio chr1_204254960_204257000 0.06 0.04 1.8e-03 0.06 0.06 0.05 0.06 5.3e-04 4.7e-04 1.3e-03 6.4e-04
4 NAcc alternative polyA XM_039099901.1 0.03 0.02 7.8e-04 0.01 0.02 0.01 0.01 1.6e-02 2.8e-03 8.3e-03 9.2e-03
5 PL intron excision ratio chr1_204254960_204281876 0.04 0.03 5.0e-05 0.04 0.03 0.03 0.04 1.6e-05 1.0e-04 5.3e-04 6.7e-05
6 LHb gene expression Macrod1 0.25 0.13 2.2e-03 0.05 0.07 0.05 0.03 2.4e-02 8.8e-03 2.4e-02 5.8e-02
7 Liver intron excision ratio chr1_204254960_204325753 0.04 0.03 8.5e-03 -0 0 0 -0 4.7e-01 2.5e-01 2.0e-01 4.2e-01
8 Liver gene expression Macrod1 0.21 0.13 8.3e-11 0.07 0.08 0.08 0.08 1.3e-08 1.7e-09 6.9e-09 9.2e-09
9 Brain gene expression Macrod1 0.07 0.04 1.7e-06 0.06 0.06 0.04 0.06 1.2e-06 5.6e-06 7.7e-05 2.7e-06
10 Brain mRNA stability Macrod1 0.07 0.04 5.2e-06 0.06 0.05 0.04 0.04 3.9e-06 1.1e-05 2.6e-04 6.2e-05
11 NAcc intron excision ratio chr1_204254960_204257000 0.03 0.02 2.4e-04 0.03 0.03 0.03 0.03 9.0e-05 2.5e-04 1.7e-04 3.5e-04
12 Brain intron excision ratio chr1_204254960_204257000 0.07 0.05 4.5e-06 0.06 0.06 0.05 0.06 2.4e-06 1.4e-06 1.5e-05 3.9e-06
13 Adipose alternative polyA XM_039099939.1 0.06 0.04 1.6e-03 0.01 0.01 0 0.01 3.0e-02 5.1e-02 1.3e-01 4.9e-02
14 PL gene expression Macrod1 0.2 0.1 1.6e-07 0.07 0.06 0.06 0.06 7.7e-08 2.2e-07 1.1e-07 6.7e-07
15 NAcc isoform ratio NM_139337.2 0.03 0.02 3.3e-03 0.01 0.02 0.01 0.01 7.6e-03 3.8e-03 1.3e-02 2.2e-02
16 NAcc intron excision ratio chr1_204386696_204386868 0.04 0.03 3.8e-04 0.01 0.03 0.03 0.03 2.0e-02 2.0e-04 3.1e-04 3.5e-04
17 NAcc isoform ratio XM_006230677.4 0.04 0.02 1.6e-04 0.02 0.04 0.03 0.03 1.1e-03 5.6e-05 8.8e-05 4.4e-04
18 NAcc gene expression Macrod1 0.05 0.03 8.5e-05 0.01 0.01 0.01 0.01 3.7e-02 6.5e-03 9.8e-03 3.9e-02
19 PL isoform ratio XM_006230677.4 0.04 0.02 7.5e-04 0.02 0.02 0.02 0.02 5.9e-03 9.7e-04 5.0e-03 5.9e-03
20 PL intron excision ratio chr1_204386585_204386868 0.03 0.02 5.9e-03 0.02 0.02 0.01 0.01 5.4e-03 2.2e-03 7.6e-03 2.0e-02
21 PL isoform ratio NM_139337.2 0.03 0.02 5.1e-03 0.02 0.02 0.02 0.01 4.3e-03 3.3e-03 4.7e-03 1.1e-02
22 Liver mRNA stability Macrod1 0.06 0.04 3.1e-04 0.04 0.02 0.02 0.03 5.2e-05 2.3e-03 1.6e-03 2.2e-04
23 PL alternative polyA XM_039099901.1 0.05 0.05 2.4e-03 0.02 0.01 0.01 0.01 1.6e-03 7.1e-03 8.8e-03 2.6e-02
24 NAcc intron excision ratio chr1_204386585_204386868 0.06 0.04 1.5e-05 0.04 0.04 0.03 0.04 3.6e-05 3.8e-05 2.2e-04 2.7e-05
25 PL intron excision ratio chr1_204386696_204386868 0.03 0.02 4.0e-03 0.01 0.02 0.01 0.01 2.2e-02 1.1e-03 1.7e-02 4.9e-02
26 PL alternative polyA XM_039099701.1 0.09 0.09 9.3e-03 0.02 0.01 0.04 0.01 1.3e-03 2.1e-02 7.6e-05 8.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.81.33.50.60.4-1.11.6-0.50.0-0.41.5-0.6-0.50.5-0.9-1.10.8-1.6-1.31.4-0.41.01.2-1.31.9-1.81.6-1.11.7
Area under the delay curve0.40.41.00.20.2-0.40.3-0.3-0.7-0.30.0-0.2-0.10.1-0.6-0.90.7-0.7-0.80.80.30.90.9-1.01.0-1.00.8-1.00.9
BMI with tail4.615.032.72.82.9-4.04.7-3.00.3-2.73.8-2.9-3.03.0-3.6-1.71.5-5.2-4.95.00.44.24.7-4.95.5-5.75.1-4.33.7
BMI without tail2.85.79.12.42.6-2.62.5-2.50.3-2.11.7-2.0-2.12.1-2.7-0.30.3-2.9-2.93.01.22.83.0-3.02.9-3.02.5-2.81.6
Body weight3.615.324.14.03.9-4.74.7-4.12.1-3.93.6-4.3-4.44.4-4.30.6-1.2-4.9-4.94.71.64.34.4-4.44.0-4.23.8-3.91.6
Weight adjusted by age1.31.53.01.51.5-1.71.7-1.51.6-1.51.6-1.5-1.51.5-1.21.1-0.7-1.3-1.21.10.20.90.9-0.90.5-0.50.6-0.6-0.1
Bone surface3.05.315.92.12.0-3.03.8-1.92.1-1.84.0-2.0-2.02.0-2.1-0.60.4-3.1-2.52.6-0.81.62.0-2.22.8-2.82.3-1.52.0
Bone volume1.32.39.70.90.7-1.72.7-0.71.2-0.63.1-0.8-0.70.7-0.9-1.10.9-2.1-1.51.6-1.40.71.1-1.32.2-2.11.8-0.71.8
Breakpoint value in progressive ratio session1.51.64.51.71.7-1.81.8-1.52.1-1.51.9-1.5-1.51.5-1.41.2-1.5-1.2-1.01.00.30.70.6-0.60.4-0.30.4-0.30.2
Number of licking bursts0.10.10.40.50.6-0.50.6-0.30.6-0.50.6-0.5-0.50.5-0.30.3-0.1-0.4-0.30.3-0.10.10.2-0.20.1-0.20.1-0.1-0.3
Context. condit. distance diff. score0.60.72.7-1.0-0.81.1-1.11.1-1.71.2-1.11.01.0-1.00.9-1.11.00.60.4-0.4-0.3-0.3-0.20.20.1-0.10.3-0.00.4
Locomotion velocity, session 10.40.52.50.30.4-0.30.1-0.5-0.7-0.4-0.3-0.5-0.40.4-0.7-0.10.3-0.6-0.70.70.70.90.9-0.90.9-0.90.6-1.01.6
Locomotion distance, session 11.31.65.30.60.6-1.01.0-0.8-0.7-0.60.5-0.9-0.80.8-1.2-0.60.7-1.5-1.51.60.51.61.7-1.71.9-1.81.6-1.72.3
Locomotion velocity, session 22.22.54.01.81.7-2.01.9-1.81.0-1.61.4-1.7-1.71.7-1.80.8-0.4-2.0-1.91.90.81.71.8-1.81.5-1.41.3-1.61.4
Locomotion distance, session 20.91.33.60.80.7-1.10.7-1.0-0.3-0.90.3-1.1-1.01.0-1.40.10.1-1.2-1.31.31.01.41.5-1.51.5-1.40.9-1.51.9
Locomotion velocity, session 31.51.75.6-0.7-0.50.00.40.5-2.00.80.10.30.5-0.5-0.0-2.12.0-1.2-1.21.3-0.61.11.4-1.52.2-2.22.4-1.51.6
Locomotion distance, session 30.20.20.6-0.2-0.1-0.00.10.1-0.60.2-0.1-0.1-0.10.1-0.1-0.30.5-0.4-0.40.40.00.40.5-0.50.6-0.80.8-0.50.6
Stereotopy head waving bouts, day 31.31.55.5-0.8-0.70.4-0.10.6-2.30.8-0.30.70.7-0.70.1-2.32.0-0.8-0.81.0-0.40.91.1-1.21.8-1.82.0-1.31.5
Stereotopy head waving duration, day 30.60.72.8-1.1-0.90.8-0.50.9-1.51.0-0.40.90.9-0.90.7-1.71.40.10.10.0-0.7-0.10.1-0.20.7-0.70.8-0.20.5
Locomotion velocity, session 70.80.93.9-0.9-0.80.5-0.11.0-1.51.2-0.10.91.0-1.00.5-2.01.5-0.3-0.30.4-0.80.20.4-0.51.0-1.11.6-0.51.0
Locomotion distance, session 70.40.51.9-0.2-0.30.0-0.20.0-1.40.2-0.60.10.1-0.1-0.3-0.70.8-0.5-0.70.70.50.90.9-0.90.9-1.01.3-1.10.7
Stereotopy head waving bouts, day 70.30.41.7-0.4-0.10.30.40.9-0.10.90.80.60.6-0.60.6-1.20.9-0.10.2-0.1-1.3-0.6-0.30.20.5-0.60.20.50.6
Stereotopy head waving duration, day 70.60.73.11.01.1-1.11.6-0.51.2-0.51.7-0.8-0.90.9-0.6-0.2-0.2-1.1-0.80.8-0.50.40.5-0.61.0-0.90.4-0.20.6
Locomotion velocity, session 81.21.44.01.31.4-1.20.6-1.30.2-1.30.2-1.3-1.21.2-1.70.5-0.5-1.0-1.01.11.41.31.3-1.31.1-1.00.2-1.42.0
Locomotion distance, session 80.71.06.5-0.30.0-0.00.30.4-1.40.60.20.30.4-0.4-0.2-1.61.6-0.7-0.60.8-0.40.60.9-1.01.7-1.71.4-1.02.6
Degree of sensitization distance0.40.41.8-0.1-0.1-0.00.10.1-1.10.2-0.10.40.3-0.3-0.2-1.10.9-0.6-0.60.7-0.00.70.8-0.81.0-0.91.3-0.90.6
Degree of sensitization stereotypy0.30.42.50.50.6-0.61.20.11.00.11.6-0.3-0.30.3-0.1-0.30.1-0.6-0.30.3-1.0-0.20.0-0.10.6-0.60.10.30.7
Conditioned locomotion1.11.22.31.41.5-1.41.1-1.40.8-1.30.8-1.3-1.41.4-1.40.6-0.5-1.2-1.21.20.91.21.1-1.10.8-0.90.5-1.00.1
Cocaine response after cond. corrected0.60.73.8-1.1-1.21.0-1.20.8-2.00.8-1.50.70.7-0.70.5-1.01.00.50.2-0.20.20.10.1-0.20.4-0.30.4-0.40.6
Cocaine response after cond. not corrected0.40.52.8-0.9-1.10.8-0.90.5-1.70.6-1.10.60.5-0.50.3-1.00.80.30.1-0.00.20.20.2-0.30.5-0.40.4-0.50.6
Cocaine response before conditioning0.30.42.20.70.4-0.81.0-0.71.5-0.81.2-0.5-0.50.5-0.50.7-0.9-0.4-0.20.2-0.2-0.0-0.00.0-0.10.2-0.20.3-0.2
Saline control response3.03.96.92.62.5-2.52.0-2.61.8-2.51.3-2.5-2.62.6-2.41.6-1.5-1.9-2.01.91.72.01.8-1.70.8-0.60.8-1.6-0.4
Bone: connectivity density2.13.36.71.61.3-2.32.6-1.61.0-1.52.3-1.7-1.61.6-1.8-0.30.1-2.5-2.22.30.11.82.0-2.02.2-2.12.0-1.71.2
Bone: cortical apparent density0.40.62.30.70.7-0.2-0.2-0.61.0-0.7-0.4-0.5-0.50.5-0.31.5-1.40.40.3-0.40.8-0.1-0.30.4-1.21.2-1.00.3-1.4
Bone: cortical area0.40.62.20.70.9-1.01.4-0.61.0-0.61.5-0.5-0.60.6-0.5-0.0-0.2-1.1-0.90.8-0.50.40.5-0.60.7-0.60.8-0.3-0.2
Bone: cortical porosity0.00.00.60.30.5-0.10.0-0.10.3-0.10.1-0.1-0.10.1-0.1-0.0-0.20.10.1-0.10.1-0.1-0.10.1-0.2-0.00.10.10.8
Bone: cortical porosity0.30.31.00.81.0-0.60.4-0.70.8-0.70.4-0.7-0.70.7-0.70.4-0.7-0.3-0.30.20.50.30.2-0.2-0.0-0.10.1-0.20.6
Bone: cortical thickness1.83.07.22.42.3-1.91.2-2.32.2-2.40.5-2.2-2.32.3-1.82.5-2.7-1.0-1.21.01.91.31.0-0.8-0.50.7-0.4-0.8-1.8
Bone: cortical thickness0.80.92.91.00.8-0.80.1-1.20.3-1.3-0.6-1.2-1.31.3-1.21.3-1.3-0.5-0.80.71.71.10.9-0.8-0.10.10.1-1.0-0.2
Bone: cortical tissue density0.50.72.80.80.8-0.3-0.2-0.71.1-0.8-0.4-0.7-0.60.6-0.41.7-1.50.40.2-0.30.9-0.0-0.30.4-1.21.2-1.00.3-1.4
Condit. Reinf. active minus inactive responses0.20.21.10.61.0-0.30.2-0.50.3-0.40.1-0.2-0.30.3-0.30.6-0.4-0.3-0.30.30.30.30.3-0.2-0.10.10.2-0.2-1.0
Condit. Reinf. active-inactive response ratio0.30.32.40.40.70.0-0.3-0.30.6-0.3-0.30.0-0.10.10.00.9-0.70.40.4-0.40.3-0.3-0.40.5-0.90.9-0.80.4-1.5
Condit. Reinf. active responses0.10.10.50.10.4-0.10.30.0-0.00.10.30.30.3-0.30.10.00.2-0.3-0.30.2-0.30.10.2-0.20.2-0.20.5-0.1-0.7
Condit. Reinf. inactive responses0.40.51.4-0.6-0.60.10.40.6-0.60.70.60.60.7-0.70.3-1.21.2-0.4-0.30.4-1.00.00.2-0.30.9-1.01.1-0.21.0
Incentive salience index mean0.30.41.20.71.1-0.70.7-0.70.1-0.60.5-0.4-0.40.4-0.60.3-0.0-0.8-0.90.80.20.80.8-0.80.6-0.50.9-0.7-0.4
Condit. Reinf. lever presses0.40.51.20.50.6-0.81.1-0.50.2-0.41.0-0.4-0.40.4-0.5-0.30.3-1.1-1.01.0-0.30.70.8-0.91.0-0.81.1-0.70.2
Condit. Reinf. active minus inactive responses0.40.51.7-0.7-0.50.60.00.80.10.90.60.90.9-0.90.8-0.80.60.40.7-0.6-1.3-1.0-0.80.7-0.10.2-0.00.90.0
Condit. Reinf. active-inactive response ratio1.51.65.4-1.4-1.10.90.11.5-0.41.71.01.71.7-1.71.4-1.81.80.40.8-0.7-2.3-1.4-1.00.80.5-0.50.41.10.6
Condit. Reinf. active responses0.00.10.30.00.3-0.00.30.10.40.00.50.10.1-0.10.2-0.1-0.10.00.2-0.2-0.5-0.4-0.30.3-0.10.2-0.00.4-0.2
Condit. Reinf. inactive responses0.60.71.91.11.2-0.70.1-1.00.5-1.3-0.4-1.2-1.21.2-1.01.1-1.2-0.3-0.50.41.40.80.6-0.5-0.20.3-0.1-0.6-0.4
Condit. Reinf. lever presses0.91.35.61.21.2-1.62.1-0.91.8-1.02.4-1.1-1.11.1-1.0-0.0-0.4-1.4-1.11.1-0.60.50.6-0.70.9-0.80.8-0.20.1
Condit. Reinf. lever reinforcers received0.10.10.90.30.5-0.30.6-0.20.9-0.30.9-0.2-0.10.1-0.00.2-0.3-0.10.1-0.1-0.5-0.3-0.30.3-0.10.2-0.10.5-0.3
Conditioned reinforcement - actives0.90.92.2-0.9-1.00.7-0.21.00.21.00.60.80.7-0.71.0-0.81.10.81.2-1.0-1.5-1.4-1.21.1-0.40.3-0.41.30.9
Conditioned reinforcement - inactives4.85.410.7-3.0-2.82.8-1.83.0-1.22.7-0.92.82.7-2.73.3-1.61.92.22.4-2.4-2.6-2.7-2.52.4-1.51.4-1.12.5-1.3
Conditioned locomotion6.98.214.6-3.8-3.83.6-2.93.6-2.23.4-2.13.33.3-3.33.8-1.81.92.92.9-2.9-2.4-2.9-2.82.8-2.12.0-1.42.6-1.9
Patch foraging indifference point 0 sec0.10.22.5-0.2-0.00.3-0.10.3-0.00.3-0.10.20.2-0.20.6-0.0-0.40.20.1-0.2-0.3-0.3-0.30.3-0.40.40.10.4-1.6
Patch foraging indifference point AUC1.92.26.02.22.2-2.12.2-1.72.5-1.72.2-1.4-1.61.6-1.51.3-1.1-1.5-1.31.20.20.80.8-0.80.4-0.60.6-0.40.1
Delay disc. indifference point, 0s delay1.11.26.00.0-0.0-0.30.1-0.1-1.60.1-0.3-0.2-0.20.2-0.8-1.21.5-0.9-1.01.10.61.21.4-1.41.4-1.91.4-1.62.5
Delay disc. indifference point, 16s delay0.70.71.8-1.0-0.80.8-0.41.2-0.71.2-0.21.21.3-1.31.1-1.30.90.40.4-0.4-1.0-0.6-0.50.5-0.30.20.10.5-0.8
Delay disc. indifference point, 2s delay0.40.41.9-0.1-0.2-0.20.40.0-0.70.10.40.50.5-0.5-0.3-1.01.4-0.6-0.50.6-0.30.40.6-0.71.0-0.90.8-0.71.1
Delay disc. indifference point, 24s delay0.20.20.90.30.3-0.0-0.5-0.4-0.3-0.4-0.9-0.3-0.20.2-0.20.6-0.40.0-0.20.10.90.50.3-0.2-0.40.50.0-0.5-0.8
Delay disc. indifference point, 4s delay0.60.61.90.40.6-0.3-0.0-0.6-1.0-0.6-0.6-0.4-0.40.4-0.8-0.10.1-0.7-1.01.01.01.21.2-1.20.9-0.90.8-1.40.6
Delay disc. indifference point, 8s delay0.50.51.50.40.3-0.3-0.1-0.4-0.8-0.5-0.5-0.6-0.50.5-0.8-0.80.4-0.5-0.60.70.90.90.9-0.90.9-0.90.3-1.11.2
Indifference point function ln k3.65.116.1-3.2-3.13.2-3.52.7-4.02.6-3.72.32.4-2.42.2-2.21.82.21.8-1.7-0.1-1.0-1.11.0-0.60.7-0.60.4-0.3
Indifference point function log k3.65.116.1-3.2-3.13.2-3.52.7-4.02.6-3.72.32.4-2.42.2-2.21.82.21.8-1.7-0.1-1.0-1.11.0-0.60.7-0.60.4-0.3
Patch foraging total patch changes 0 sec0.10.23.0-0.00.10.3-0.30.1-0.00.1-0.5-0.0-0.10.10.40.4-0.80.30.1-0.20.2-0.1-0.20.3-0.50.6-0.10.2-1.7
Patch foraging total patch changes 12 sec3.03.97.02.72.4-2.62.5-2.22.5-2.32.1-2.4-2.62.6-2.01.6-2.1-2.1-2.11.90.81.61.5-1.50.9-0.91.3-1.1-0.5
Patch foraging total patch changes 18 sec0.40.51.91.11.1-0.91.1-0.81.4-0.71.2-0.6-0.70.7-0.50.7-0.8-0.6-0.40.4-0.10.10.1-0.10.0-0.00.40.1-0.7
Patch foraging total patch changes 24 sec2.02.44.92.02.2-1.91.9-1.71.9-2.01.4-1.7-1.91.9-1.21.8-1.6-1.6-1.71.50.61.31.2-1.10.3-0.31.3-0.9-1.6
Patch foraging total patch changes 6 sec0.81.22.01.31.4-1.31.2-1.10.5-1.10.7-1.0-1.21.2-1.10.6-0.5-1.3-1.41.30.71.31.2-1.20.8-0.91.1-1.1-0.5
Patch foraging time to switch 0 sec1.62.45.61.11.0-1.82.4-1.10.7-0.92.3-1.1-1.01.0-1.4-0.60.9-2.2-1.81.9-0.51.31.6-1.72.1-1.92.1-1.31.9
Patch foraging water rate 0 sec3.15.08.7-2.3-2.22.8-2.92.1-1.41.9-2.72.32.2-2.22.5-0.2-0.22.82.5-2.6-0.5-2.1-2.32.4-2.42.4-2.02.0-2.8
Patch foraging water rate 12 sec4.57.018.4-3.0-2.73.6-4.22.6-3.02.2-4.32.82.8-2.82.8-0.50.43.32.7-2.80.2-1.9-2.22.3-2.52.3-2.31.6-2.2
Patch foraging water rate 18 sec1.41.97.0-1.8-1.82.0-2.41.4-2.31.3-2.61.41.4-1.41.3-0.60.61.51.1-1.20.3-0.6-0.70.7-0.70.8-0.70.3-1.0
Patch foraging water rate 24 sec2.02.86.6-2.2-2.32.3-2.61.6-2.01.3-2.61.71.7-1.71.7-0.40.62.01.7-1.7-0.1-1.2-1.31.4-1.21.3-1.51.0-1.4
Patch foraging water rate 6 sec2.23.211.0-2.0-2.02.5-3.01.5-2.31.5-3.32.02.0-2.01.7-0.10.12.21.6-1.70.6-0.9-1.21.3-1.71.6-1.30.7-1.8
Seeking ratio, delayed vs. immediate footshock0.10.10.6-0.3-0.10.4-0.50.0-0.40.3-0.60.10.1-0.10.4-0.0-0.10.40.2-0.30.1-0.1-0.20.2-0.40.40.00.1-0.8
Distance traveled before self-admin0.30.32.00.50.5-0.71.2-0.31.1-0.21.4-0.5-0.40.4-0.1-0.0-0.4-0.7-0.50.4-0.70.00.1-0.20.3-0.20.40.2-0.4
Distance traveled after self-admin0.10.20.90.10.2-0.20.4-0.00.9-0.10.6-0.1-0.10.10.20.5-0.60.10.2-0.3-0.4-0.4-0.40.5-0.30.4-0.60.6-0.3
Extensor digitorum longus weight5.320.835.15.55.5-5.95.7-5.43.9-5.14.5-5.2-5.25.2-5.22.3-2.3-5.4-5.35.12.34.64.6-4.63.4-3.53.3-3.90.8
Bone: elastic displacement1.01.15.3-0.7-0.71.3-2.00.5-1.10.5-2.30.50.6-0.60.60.7-0.61.51.1-1.11.1-0.4-0.70.8-1.41.3-1.20.4-0.5
Bone: elastic work1.01.23.81.31.3-0.90.1-1.40.3-1.5-0.7-1.5-1.41.4-1.41.3-1.5-0.6-1.00.91.91.41.1-1.00.00.00.2-1.2-0.2
Bone: endosteal estimation1.43.211.7-1.6-1.40.60.51.5-2.21.70.91.71.6-1.60.8-3.43.4-0.9-0.50.7-2.20.00.6-0.82.5-2.52.5-0.62.8
Bone: endosteal perimeter1.94.014.6-2.0-1.70.90.62.1-1.92.31.52.22.1-2.11.4-3.83.7-0.60.00.3-3.1-0.7-0.0-0.32.4-2.42.20.12.9
Epididymis fat weight1.32.97.6-2.6-2.42.1-1.12.4-2.42.7-0.82.02.1-2.12.2-2.81.70.80.8-0.8-2.0-1.1-0.80.60.5-0.60.80.70.5
Delta time in closed arm before/after self-admin0.90.92.80.4-0.1-0.2-0.4-0.7-1.2-0.4-1.4-0.7-0.70.7-0.7-0.1-0.8-0.6-1.11.01.71.51.3-1.20.2-0.21.0-1.6-1.0
Delta time in open arm before/after self-admin0.50.52.10.10.6-0.20.70.01.4-0.11.20.1-0.00.00.50.9-0.40.10.4-0.4-1.1-0.8-0.80.8-0.60.7-0.61.1-1.4
Diff in mean of infusions in LGA sessions0.50.65.20.80.8-0.50.4-0.61.2-0.70.3-0.4-0.40.4-0.31.5-2.3-0.0-0.1-0.00.40.0-0.10.2-0.61.0-0.30.3-1.1
Delay discount exponential model param0.30.40.9-0.3-0.30.4-0.30.40.60.40.00.20.1-0.10.60.7-0.50.70.7-0.8-0.4-0.8-0.90.9-0.80.9-0.71.0-0.6
Extinction: sum of active levers before priming3.03.05.82.22.4-2.32.3-2.12.0-2.02.1-1.9-2.02.0-1.91.3-1.2-1.9-1.71.70.61.41.4-1.41.0-1.41.0-1.11.2
Active lever presses in extinction session 61.31.25.21.51.4-1.41.7-1.12.3-1.11.9-1.3-1.21.2-0.81.4-1.8-0.9-0.60.5-0.10.20.2-0.10.00.2-0.00.2-0.4
Bone: final force2.23.57.42.02.0-2.42.7-1.91.5-1.82.5-1.7-1.81.8-1.90.1-0.2-2.5-2.32.30.21.81.9-2.02.0-1.91.9-1.61.4
Bone: final moment1.93.26.71.81.9-2.32.6-1.81.4-1.72.3-1.7-1.61.6-1.80.1-0.2-2.4-2.22.10.11.71.8-1.91.9-1.81.8-1.51.4
Food consumed during 24 hour testing period0.30.30.90.00.10.10.10.11.0-0.00.4-0.0-0.10.10.50.7-0.00.40.5-0.6-0.5-0.7-0.80.8-1.00.9-0.90.9-0.8
Glucose1.52.26.8-2.0-2.31.4-0.81.8-2.22.0-0.41.71.7-1.71.3-2.42.60.40.6-0.4-1.5-0.7-0.30.20.9-1.10.80.12.0
Heart weight1.62.37.4-2.4-2.72.1-2.01.9-2.61.9-2.01.61.7-1.71.6-1.41.51.21.0-0.9-0.5-0.7-0.60.6-0.0-0.10.00.20.2
Delay discount hyperbolic model param0.40.51.1-0.4-0.40.5-0.40.40.60.4-0.00.20.1-0.10.70.7-0.60.80.8-0.9-0.4-0.9-1.01.0-1.01.0-0.81.0-0.8
Intermittent access intake day 1-15 change1.21.23.1-0.9-0.71.0-0.61.00.50.90.10.80.7-0.71.30.00.21.31.5-1.5-1.2-1.7-1.71.6-1.11.0-1.31.8-0.3
Intermittent access intake escalation1.00.92.4-0.8-0.70.9-0.51.00.40.90.10.70.6-0.61.2-0.20.11.11.3-1.3-1.2-1.5-1.41.4-0.90.8-1.11.5-0.4
Intermittent access intake escalation 20.80.82.3-0.5-0.40.6-0.20.70.80.50.30.60.4-0.41.10.4-0.50.91.0-1.1-1.1-1.3-1.31.3-1.11.0-1.01.5-1.1
Intermitt. access day 1 inactive lever presses1.92.14.1-1.8-1.61.7-1.31.9-1.21.8-0.82.02.0-2.01.8-1.41.21.31.4-1.4-1.3-1.5-1.31.3-0.60.7-0.61.20.0
Intermitt. access day 15 inactive lever presses2.83.06.5-2.2-2.12.0-0.92.4-1.12.3-0.22.52.4-2.42.6-1.61.61.21.3-1.4-2.4-1.8-1.51.5-0.80.50.11.6-0.9
Intermitt. access escalation Index1.11.03.9-1.5-1.61.4-1.51.1-2.01.2-1.81.00.9-0.91.0-1.00.80.80.5-0.50.1-0.2-0.20.2-0.40.20.2-0.1-0.4
Intermittent access day 1 total infusions3.94.515.9-3.0-3.02.2-1.12.9-3.12.8-0.52.52.3-2.32.2-4.03.80.50.7-0.5-2.4-1.0-0.50.31.1-1.21.50.31.2
Intermittent access day 15 total infusions5.86.513.4-3.7-3.53.0-1.83.6-2.43.4-0.73.02.8-2.83.3-3.53.11.92.2-2.0-3.2-2.5-2.11.9-0.20.2-0.12.00.5
Intermittent access terminal intake (last 3 days)4.14.512.9-3.1-2.92.3-0.83.0-2.02.90.22.52.3-2.32.8-3.63.00.91.3-1.2-3.3-1.9-1.41.20.6-0.60.71.40.7
Intermittent access total infusions3.74.112.5-2.9-2.92.2-0.92.9-2.22.9-0.12.52.2-2.22.5-3.53.10.91.2-1.0-2.8-1.6-1.21.00.6-0.50.91.10.7
Intermittent access day 1 locomotion2.52.610.8-2.2-2.31.5-0.82.0-3.02.0-0.71.51.5-1.51.3-3.32.9-0.1-0.10.2-1.4-0.00.3-0.51.4-1.51.6-0.60.9
Intermittent access day 15 total locomotion3.23.57.7-2.8-2.72.2-1.12.7-1.82.5-0.42.32.2-2.22.6-2.62.11.11.3-1.3-2.5-1.7-1.41.3-0.10.10.21.4-0.6
Intermittent access total locomotion4.45.016.0-3.2-3.22.3-0.73.1-2.73.20.02.82.7-2.72.8-4.03.50.50.8-0.7-3.3-1.4-0.90.70.9-0.91.30.90.2
Intermittent access standard deviation1.31.32.6-1.4-1.31.4-0.91.4-0.21.3-0.30.90.7-0.71.5-0.50.01.31.5-1.5-1.3-1.6-1.61.5-0.80.8-1.11.6-0.5
Left kidney weight0.41.13.6-1.7-1.91.2-0.61.3-0.91.4-0.21.31.3-1.31.4-1.31.10.60.7-0.7-1.3-0.9-0.80.7-0.1-0.00.10.8-0.8
Right kidney weight0.20.73.2-1.1-1.00.60.21.1-0.01.10.80.80.9-0.91.3-1.00.70.20.4-0.5-1.8-0.9-0.70.70.1-0.20.40.9-0.5
Cocaine induced anxiety0.10.10.70.10.2-0.20.50.10.4-0.00.80.50.5-0.50.2-0.20.5-0.2-0.00.1-0.8-0.3-0.10.10.3-0.40.10.20.0
Post-drug Anxiety0.60.62.81.01.1-1.11.4-0.71.4-0.71.7-0.8-0.70.7-0.60.2-0.2-0.8-0.50.5-0.50.10.2-0.30.5-0.70.20.00.8
Baseline Anxiety1.61.74.31.61.5-1.51.1-1.51.2-1.50.7-2.1-2.02.0-1.51.1-1.7-1.0-1.21.11.21.21.0-1.00.5-0.50.6-0.90.7
Tail length0.82.46.72.22.2-1.50.6-2.11.7-2.00.0-1.8-2.02.0-1.72.3-2.6-0.6-0.90.72.11.20.8-0.6-0.60.7-0.6-0.7-1.9
Length with tail1.45.09.22.82.7-2.82.3-2.82.3-2.81.5-3.0-3.03.0-2.52.1-2.5-2.2-2.32.11.82.11.9-1.80.8-0.80.8-1.6-0.6
Length without tail1.12.44.41.51.2-1.92.0-1.51.3-1.61.6-2.1-2.02.0-1.50.7-1.2-1.9-1.91.80.61.51.5-1.51.2-1.31.4-1.20.6
Times rat made contact with spout0.60.71.81.11.3-0.70.1-1.00.7-1.2-0.3-1.0-1.11.1-0.91.4-1.1-0.1-0.30.31.20.60.4-0.3-0.40.4-0.5-0.4-0.8
Lifetime Intake3.03.411.5-2.7-2.72.0-1.02.6-2.42.6-0.42.22.0-2.02.1-3.42.70.70.9-0.8-2.3-1.2-0.80.60.8-0.80.90.70.9
Liver weight, left0.20.31.1-0.1-0.00.10.10.2-0.70.50.20.30.3-0.3-0.2-1.10.9-0.3-0.20.3-0.20.20.3-0.41.0-0.90.4-0.40.9
Liver weight, right0.71.23.20.20.5-0.40.4-0.2-1.4-0.2-0.1-0.2-0.20.2-0.7-1.10.8-1.1-1.21.30.41.31.5-1.51.8-1.81.7-1.61.7
Locomotor activity1.01.56.4-1.3-1.31.8-2.31.0-1.60.8-2.50.91.0-1.01.00.1-0.71.71.2-1.30.7-0.6-0.80.9-1.11.2-1.10.5-0.9
Locomotor testing distance1.11.810.3-1.4-1.41.9-2.71.1-2.30.8-3.21.01.0-1.01.00.0-0.41.71.1-1.21.2-0.3-0.60.7-1.11.2-0.90.1-0.9
Locomotor testing rearing0.81.35.9-1.3-1.31.7-2.11.1-2.00.9-2.40.91.0-1.01.0-0.40.01.30.9-1.00.6-0.4-0.50.6-0.60.9-0.60.1-0.3
Locomotion in novel chamber3.44.38.5-2.9-2.62.5-1.42.9-1.52.9-0.52.32.2-2.22.9-2.02.01.72.0-1.9-2.7-2.3-2.01.9-0.70.9-0.32.0-0.3
Locomotion in novel chamber post-restriction2.32.84.7-2.1-2.12.1-1.72.0-1.42.1-1.12.22.2-2.21.9-2.01.41.71.8-1.7-1.3-1.7-1.61.5-0.80.9-0.91.4-0.2
Fecal boli incidents, locomotor time 10.30.42.4-0.10.0-0.30.90.20.90.31.60.40.4-0.40.3-0.50.7-0.20.2-0.1-1.4-0.7-0.40.30.3-0.50.20.70.7
Change in fecal boli incidents, locomotor task0.70.72.00.20.2-0.1-0.5-0.5-1.4-0.5-1.2-0.3-0.30.3-0.9-0.40.9-0.3-0.60.71.41.11.1-1.10.8-0.60.7-1.41.1
Time >=10cm from walls, locomotor time 11.51.55.8-1.1-1.00.50.51.3-0.81.51.31.31.3-1.30.8-2.12.4-0.20.3-0.1-2.2-0.8-0.40.11.3-1.31.00.42.2
Bouts of movement, locomotor time 11.82.06.91.11.0-0.40.0-0.82.5-1.00.2-0.8-0.80.8-0.12.5-2.60.80.8-1.00.6-0.8-1.11.3-2.11.9-2.21.4-2.0
Total resting periods, locomotor time 11.41.55.20.80.7-0.30.1-0.62.3-0.70.3-0.7-0.60.60.12.2-2.20.80.8-0.90.3-0.9-1.21.3-1.91.7-1.91.4-1.8
Rest time, locomotor task time 11.61.82.8-1.1-0.91.5-1.61.1-0.51.2-1.21.51.6-1.61.40.10.61.71.7-1.6-0.5-1.5-1.51.5-1.51.6-1.31.4-1.1
Distance moved, locomotor task time 10.70.82.80.30.6-0.70.9-0.4-0.2-0.40.7-0.9-0.90.9-0.7-0.60.0-1.1-1.01.00.10.91.0-1.11.4-1.70.8-0.91.5
Vertical activity count, locomotor time 10.60.61.8-1.2-0.91.0-0.81.1-1.31.1-0.60.70.7-0.70.8-1.30.60.50.5-0.5-0.6-0.5-0.30.30.3-0.5-0.10.21.0
Time >=10cm from walls, locomotor time 20.40.41.20.10.40.10.30.40.90.30.80.40.4-0.40.50.2-0.10.40.7-0.7-1.0-1.0-0.90.9-0.40.6-0.71.1-0.2
Bouts of movement, locomotor time 20.30.41.40.70.5-0.50.4-0.61.0-0.60.2-0.8-0.90.9-0.20.9-1.2-0.2-0.30.10.40.20.00.1-0.60.5-0.30.1-1.1
Total resting periods, locomotor time 20.20.20.60.40.2-0.30.3-0.40.7-0.30.2-0.6-0.60.6-0.10.5-0.8-0.1-0.10.00.10.0-0.10.1-0.40.4-0.30.2-0.8
Rest time, locomotor task time 21.51.83.5-1.8-1.91.7-1.51.6-1.81.8-1.11.61.6-1.61.4-1.41.71.21.3-1.1-0.9-1.1-1.00.9-0.20.4-0.20.70.6
Distance moved, locomotor task time 20.80.92.91.21.5-1.00.8-1.01.5-1.30.7-1.3-1.31.3-0.91.4-1.7-0.5-0.50.40.70.40.3-0.2-0.1-0.2-0.5-0.1-0.1
Vertical activity count, locomotor time 20.40.52.50.10.30.2-0.9-0.30.1-0.5-1.1-0.2-0.20.2-0.21.3-1.60.70.4-0.51.1-0.0-0.30.4-0.80.7-1.10.2-0.7
Light reinforcement 10.30.52.6-0.10.10.6-0.70.20.10.3-0.60.20.2-0.20.60.6-0.70.80.7-0.80.0-0.7-0.80.8-1.11.0-0.80.8-1.6
Light reinforcement 21.82.46.4-1.8-1.91.4-0.32.1-0.32.30.61.92.0-2.02.2-1.61.40.91.3-1.2-2.5-1.8-1.61.4-0.70.50.01.7-0.2
Bone: marrow area1.53.111.6-1.6-1.40.60.41.6-2.31.70.81.71.6-1.60.8-3.43.4-0.8-0.50.7-2.10.10.6-0.92.5-2.52.5-0.72.8
Bone: maximum diameter0.40.74.30.00.3-0.61.60.20.70.22.10.20.2-0.20.1-1.11.0-1.0-0.60.6-1.6-0.10.2-0.31.3-1.21.10.10.5
Bone: maximum force3.05.212.61.81.9-2.73.5-1.71.3-1.53.4-1.5-1.51.5-1.9-0.80.8-3.3-2.82.9-0.72.02.4-2.53.0-2.93.1-1.92.0
Bone: maximum moment2.74.610.91.71.7-2.53.3-1.61.2-1.43.2-1.4-1.41.4-1.8-0.80.7-3.1-2.72.7-0.61.92.3-2.42.8-2.82.9-1.81.9
Mean time between licks in bursts1.01.44.71.31.0-0.9-0.0-1.4-0.0-1.5-0.9-1.7-1.61.6-1.41.4-1.3-0.7-1.11.02.21.61.3-1.20.1-0.10.4-1.4-0.0
Mean num. licks in bursts0.20.20.9-0.1-0.10.4-0.80.0-0.30.1-0.90.20.2-0.20.10.4-0.40.60.4-0.50.6-0.1-0.30.3-0.60.7-0.60.1-0.2
Cd content in liver1.11.22.3-1.1-0.61.1-0.61.4-0.11.10.11.51.5-1.51.4-0.70.91.01.3-1.2-1.5-1.5-1.41.3-0.50.6-0.71.40.4
Co content in liver1.82.17.2-0.5-0.31.5-2.40.5-0.70.4-2.70.60.6-0.60.71.4-1.02.11.6-1.71.3-0.9-1.21.4-2.22.0-2.20.9-1.9
Cu content in liver0.10.20.90.60.6-0.40.3-0.60.7-0.50.3-0.3-0.30.3-0.30.9-0.4-0.1-0.10.10.30.10.00.0-0.30.1-0.30.0-0.5
Fe content in liver0.20.31.40.40.5-0.60.9-0.20.50.01.20.10.1-0.1-0.3-0.30.5-0.6-0.30.4-0.60.10.2-0.30.7-0.70.5-0.11.0
K content in liver2.42.34.31.31.4-1.71.8-1.40.2-0.91.4-1.3-1.31.3-1.6-0.50.4-2.1-2.02.00.41.81.9-2.02.0-2.02.1-1.80.6
Mg content in liver0.70.72.80.20.3-0.50.8-0.1-0.60.20.6-0.1-0.10.1-0.4-0.91.0-1.1-1.01.1-0.30.81.0-1.11.3-1.41.7-1.00.4
Mn content in liver1.01.24.31.41.5-1.51.9-1.11.9-0.82.1-1.1-1.11.1-0.80.6-0.7-1.3-1.00.9-0.40.40.5-0.50.4-0.50.7-0.10.3
Na content in liver0.60.61.51.01.1-1.01.2-0.80.9-0.61.2-0.8-0.80.8-0.70.1-0.1-1.0-0.80.8-0.10.60.6-0.60.6-0.50.8-0.4-0.2
Rb content in liver0.91.13.1-1.4-1.31.3-1.11.3-1.81.4-1.01.31.3-1.30.9-1.51.40.70.6-0.5-0.6-0.5-0.30.30.3-0.30.50.11.0
Se content in liver0.60.73.9-0.5-0.50.10.80.70.90.81.60.90.9-0.91.0-0.60.70.00.5-0.5-2.0-1.1-0.90.8-0.20.1-0.11.2-0.6
Sr content in liver1.91.75.01.81.6-1.61.5-1.72.2-1.61.3-1.7-1.71.7-1.01.6-1.8-0.9-0.90.70.60.60.5-0.4-0.50.4-0.3-0.1-1.7
Zn content in liver0.70.81.71.00.9-1.11.3-1.01.1-0.81.1-1.1-1.11.1-0.60.9-0.7-1.1-1.11.00.10.70.7-0.70.3-0.50.7-0.5-1.1
Bone: minimum diameter1.22.28.3-1.4-1.20.60.41.4-1.81.60.81.71.6-1.60.9-2.92.8-0.7-0.40.6-2.0-0.00.4-0.62.0-1.82.1-0.51.7
Time in familiar zone, hab. session 10.10.10.4-0.4-0.30.3-0.20.5-0.60.3-0.30.30.2-0.20.3-0.60.40.0-0.10.0-0.20.00.1-0.10.0-0.10.5-0.1-0.1
Time in novel zone, hab. session 10.20.10.9-0.2-0.30.3-0.7-0.1-0.70.1-0.90.00.1-0.1-0.20.20.00.30.2-0.10.70.20.1-0.10.1-0.1-0.4-0.30.7
Total zone transitions, hab. session 10.30.52.11.01.5-0.80.8-0.70.6-0.70.7-0.9-0.80.8-0.70.4-0.2-0.7-0.60.60.20.50.5-0.50.6-0.50.3-0.40.7
Total locomotion distance, hab. session 10.30.52.1-0.6-0.00.5-0.10.7-1.20.9-0.00.50.7-0.70.4-1.31.5-0.2-0.10.2-0.70.00.2-0.30.8-0.90.9-0.31.0
Locomotion velocity, hab. session 10.10.20.7-0.10.50.10.10.2-0.60.40.20.10.2-0.20.1-0.70.8-0.3-0.20.3-0.40.10.3-0.30.6-0.70.7-0.30.5
Time in familiar zone, hab. session 20.50.52.70.60.4-0.2-0.6-0.7-0.3-0.8-1.2-0.8-0.80.8-0.80.8-0.90.1-0.20.21.70.70.5-0.4-0.40.3-0.3-0.7-0.0
Time in novel zone, hab. session 20.20.20.8-0.2-0.1-0.10.60.10.20.30.90.30.3-0.30.3-0.30.7-0.4-0.30.3-0.9-0.10.0-0.10.6-0.50.40.10.2
Total zone transitions, hab. session 21.62.13.91.11.4-1.51.5-1.20.0-1.01.1-1.5-1.41.4-1.5-0.30.3-1.8-1.81.80.51.71.8-1.82.0-1.91.8-1.71.4
Total locomotion distance, hab. session 20.70.92.6-0.00.5-0.30.4-0.2-1.20.00.1-0.2-0.20.2-0.5-1.11.3-1.0-1.01.10.11.01.2-1.21.5-1.61.6-1.31.2
Locomotion velocity, hab. session 20.60.82.6-0.40.2-0.00.30.2-1.30.40.20.10.2-0.2-0.1-1.51.6-0.8-0.70.8-0.40.70.9-1.01.5-1.51.6-1.01.3
Novel to familiar place preference ratio0.60.74.50.60.2-1.11.8-0.51.6-0.52.1-0.7-0.60.6-0.30.1-0.2-1.0-0.70.6-1.00.00.2-0.20.6-0.50.50.20.1
Novelty place preference0.40.43.00.3-0.2-0.71.3-0.21.3-0.21.7-0.3-0.20.2-0.00.0-0.1-0.7-0.30.3-1.1-0.2-0.10.00.3-0.30.30.40.0
Time in novel zone, NPP test0.30.32.40.3-0.2-0.71.2-0.21.1-0.21.5-0.3-0.20.2-0.0-0.0-0.1-0.7-0.40.4-0.9-0.10.1-0.10.4-0.40.40.20.1
Total zone transitions, NPP test1.82.53.81.71.9-2.02.0-1.61.0-1.51.7-1.8-1.71.7-1.80.4-0.2-1.9-1.71.80.51.51.6-1.61.7-1.71.2-1.41.8
Total locomotion distance, NPP test0.40.62.20.10.5-0.30.4-0.2-0.8-0.00.2-0.3-0.30.3-0.5-0.80.9-0.8-0.80.90.10.80.9-1.01.3-1.41.2-1.01.5
Locomotion velocity, NPP test0.20.31.60.10.5-0.30.3-0.1-0.5-0.00.3-0.3-0.30.3-0.4-0.60.8-0.6-0.50.60.00.50.6-0.70.9-1.00.8-0.71.2
Intraocular pressure2.23.16.5-1.5-1.51.5-1.11.40.81.2-0.31.51.5-1.52.10.8-0.32.02.1-2.2-1.5-2.4-2.42.4-2.21.9-2.12.6-2.0
Delta distance traveled before/after self-admin0.10.10.7-0.1-0.00.2-0.7-0.0-0.4-0.2-0.80.0-0.10.1-0.20.4-0.30.40.3-0.20.70.1-0.00.1-0.10.1-0.5-0.10.4
Delta ambulatory time before/after self-admin0.20.21.00.10.20.1-0.6-0.3-0.5-0.4-0.9-0.1-0.20.2-0.50.7-0.20.30.1-0.11.00.30.2-0.10.1-0.1-0.6-0.40.9
Parametrial fat weight1.22.37.9-2.0-1.91.3-0.61.9-2.41.9-0.21.51.4-1.41.3-2.82.80.10.3-0.1-1.7-0.4-0.0-0.11.4-1.51.3-0.11.9
Pavlov. Cond. lever latency0.40.51.3-0.6-0.60.8-1.00.6-0.30.6-0.80.40.4-0.40.50.1-0.21.01.0-1.00.1-0.8-0.80.8-0.60.5-1.10.7-0.1
Pavlov. Cond. magazine entry latency0.40.51.30.50.7-0.81.1-0.40.3-0.31.1-0.4-0.40.4-0.4-0.20.4-1.0-0.90.9-0.40.60.7-0.80.8-0.71.2-0.60.1
Pavlov. Cond. change in total contacts0.20.21.5-0.3-0.4-0.10.70.30.60.31.20.50.5-0.50.5-0.20.6-0.20.1-0.1-1.2-0.5-0.40.30.00.00.20.6-0.2
Pavlov. Cond. index score0.10.10.50.40.5-0.50.7-0.40.7-0.40.7-0.3-0.30.3-0.10.3-0.2-0.4-0.30.3-0.30.10.1-0.1-0.10.20.20.1-0.4
Pavlov. Cond. latency score0.10.10.40.40.5-0.40.6-0.40.4-0.30.6-0.3-0.20.2-0.20.10.1-0.5-0.50.4-0.10.30.3-0.30.10.00.5-0.2-0.2
Pavlov. Cond. lever contacts0.10.10.50.30.3-0.40.4-0.4-0.1-0.30.2-0.2-0.20.2-0.3-0.10.2-0.5-0.60.60.10.50.5-0.50.4-0.30.7-0.50.1
Pavlov. Cond. magazine entry number0.20.31.6-0.4-0.50.4-0.70.3-1.30.3-1.00.30.2-0.2-0.0-0.60.50.1-0.00.10.50.40.4-0.40.5-0.50.3-0.60.9
Pavlov. Cond. intertrial magazine entries1.41.73.2-1.0-1.11.2-1.11.10.31.0-0.61.31.2-1.21.40.3-0.41.51.5-1.6-0.7-1.6-1.71.7-1.71.8-1.51.7-1.7
Pavlov. Cond. lever-magazine prob. diff.0.20.30.90.70.8-0.70.9-0.60.9-0.61.0-0.5-0.50.5-0.40.4-0.2-0.6-0.50.5-0.20.30.3-0.30.10.00.3-0.1-0.2
Pavlov. Cond. response bias0.10.10.70.30.4-0.30.5-0.30.7-0.20.6-0.1-0.10.10.10.3-0.2-0.2-0.20.1-0.4-0.1-0.10.1-0.30.30.10.2-0.8
Pavlov. Cond. lever latency0.40.52.6-0.4-0.40.8-1.40.3-0.80.4-1.60.50.5-0.50.30.4-0.01.00.8-0.80.8-0.3-0.50.5-0.90.7-0.90.2-0.4
Pavlov. Cond. magazine entry latency2.32.74.72.01.9-2.22.2-1.92.0-2.01.9-2.2-2.12.1-1.71.1-1.7-1.8-1.71.60.71.31.3-1.20.9-0.80.9-0.9-0.2
Pavlov. Cond. change in total contacts0.71.07.30.80.8-1.32.2-0.52.1-0.52.7-0.6-0.60.6-0.30.0-0.4-1.2-0.70.7-1.4-0.10.1-0.20.6-0.50.50.40.5
Pavlov. Cond. index score1.31.66.11.31.1-1.82.3-1.11.9-1.22.5-1.3-1.41.4-1.00.3-0.8-1.6-1.31.3-0.50.70.8-0.81.0-0.91.0-0.40.2
Pavlov. Cond. latency score1.11.45.61.11.0-1.62.2-0.91.7-1.12.4-1.2-1.21.2-0.90.0-0.6-1.6-1.31.2-0.60.60.8-0.91.2-1.01.1-0.40.3
Pavlov. Cond. lever contacts0.20.31.80.40.3-0.71.1-0.31.2-0.51.3-0.5-0.50.5-0.20.1-0.6-0.5-0.30.3-0.6-0.1-0.00.00.2-0.00.10.3-0.3
Pavlov. Cond. magazine entry number3.44.19.2-2.5-2.42.8-3.02.2-2.92.3-2.92.52.5-2.52.0-1.31.82.32.1-1.9-0.3-1.4-1.41.4-1.11.1-1.10.9-0.1
Pavlov. Cond. intertrial magazine entries0.70.91.6-1.0-0.71.2-1.11.0-0.81.0-0.81.31.3-1.31.0-0.60.81.21.2-1.1-0.5-1.0-1.01.0-0.60.6-0.80.90.0
Pavlov. Cond. lever-magazine prob. diff.1.52.06.31.51.4-2.02.4-1.42.1-1.52.5-1.6-1.61.6-1.20.5-1.0-1.7-1.41.4-0.30.80.9-0.91.0-0.90.9-0.50.2
Pavlov. Cond. response bias0.81.24.11.21.0-1.51.9-0.91.9-1.12.0-1.3-1.31.3-0.90.5-1.0-1.2-1.00.9-0.30.40.5-0.50.6-0.50.5-0.1-0.1
Time in closed arm before self-admin0.20.21.4-0.00.2-0.30.70.20.60.01.20.10.1-0.10.10.20.8-0.30.10.0-1.0-0.4-0.20.10.6-0.40.20.41.2
Time in closed arm after self-admin0.20.21.0-0.3-0.40.2-0.50.2-1.00.2-0.80.10.1-0.1-0.1-0.10.50.0-0.10.20.50.40.4-0.40.4-0.30.6-0.60.9
Time in open arm before self-admin0.60.75.4-0.1-0.30.6-1.6-0.2-1.5-0.1-2.3-0.1-0.30.3-0.3-0.1-0.90.60.0-0.11.90.70.5-0.3-0.50.5-0.3-0.8-0.5
Time in open arm after self-admin0.60.73.6-0.10.00.4-0.8-0.00.4-0.1-0.8-0.0-0.10.10.30.9-1.30.90.7-0.80.5-0.5-0.70.8-1.31.2-1.40.7-1.9
Bone: periosteal estimation0.81.65.2-0.5-0.3-0.31.40.6-0.60.71.70.80.7-0.70.3-2.32.1-1.3-0.91.0-1.80.20.7-0.92.1-2.02.1-0.51.5
Bone: periosteal perimeter0.50.92.8-0.10.1-0.51.30.30.00.31.70.30.2-0.20.0-1.51.3-1.1-0.70.8-1.40.10.5-0.61.6-1.51.4-0.31.3
Bone: post-yield work2.73.710.5-0.5-0.3-0.92.40.7-0.40.93.20.70.7-0.7-0.0-3.13.0-2.0-1.31.6-2.80.31.0-1.33.2-3.02.9-0.73.2
Progressive ratio test 1 active lever presses2.72.85.5-2.2-2.12.0-1.62.1-1.42.1-0.92.32.2-2.22.0-1.61.61.61.7-1.6-1.5-1.7-1.61.5-0.70.6-0.61.40.1
Progressive ratio test 1 breakpoint2.32.44.7-2.0-1.91.9-1.51.9-1.31.9-0.92.22.0-2.01.9-1.41.51.51.7-1.6-1.4-1.7-1.51.4-0.70.6-0.81.40.3
Progressive ratio test 1 inactive lever presses0.60.61.9-1.3-1.41.2-1.01.2-1.20.9-1.10.90.7-0.71.1-0.70.30.70.5-0.6-0.4-0.5-0.50.5-0.20.1-0.20.4-0.5
Progressive ratio test 2 active lever presses3.94.27.8-2.8-2.62.4-1.42.8-1.62.7-0.52.82.6-2.62.7-2.42.21.61.9-1.7-2.6-2.1-1.81.7-0.60.6-0.11.80.0
Progressive ratio test 2 breakpoint5.15.710.2-3.1-2.92.9-2.03.1-1.73.0-1.13.23.0-3.03.1-2.12.12.22.4-2.3-2.5-2.6-2.42.2-1.31.3-0.72.2-0.3
Progressive ratio test 2 inactive lever presses6.17.114.4-3.8-3.53.3-2.03.7-2.23.4-1.03.33.2-3.23.7-2.92.52.22.3-2.3-3.2-2.7-2.42.3-0.90.8-0.42.3-0.9
Incentive Sensitization - Responses0.60.62.1-1.0-0.90.8-0.11.1-0.31.10.31.00.9-0.91.2-1.10.90.30.5-0.5-1.5-0.8-0.70.6-0.20.30.40.8-0.5
Incentive Sensitization - Breakpoint0.90.92.6-1.2-1.01.0-0.31.3-0.51.30.21.31.1-1.11.5-1.21.00.50.7-0.7-1.6-1.0-0.90.8-0.30.40.40.9-0.6
Sum of active levers in priming session hrs 5-61.21.16.70.70.6-0.61.1-0.22.6-0.41.8-0.3-0.50.50.31.6-1.40.10.5-0.6-1.1-1.1-1.11.1-1.11.0-0.81.5-0.8
Progressive ratio2.32.76.11.61.8-1.92.2-1.40.9-1.12.1-1.6-1.51.5-1.7-0.60.3-2.0-1.71.8-0.01.31.6-1.72.1-2.11.8-1.32.5
Food seeking constrained by brief footshock0.40.51.50.60.4-0.6-0.0-0.9-0.2-0.8-0.5-0.8-0.80.8-1.00.8-0.3-0.4-0.60.61.20.90.8-0.80.3-0.20.0-1.00.6
Seeking ratio, punishment vs. effort1.41.86.9-1.2-1.61.6-2.30.9-1.40.7-2.61.01.0-1.01.00.8-0.31.61.1-1.21.0-0.5-0.80.9-1.71.7-1.40.4-1.9
Retroperitoneal fat weight3.110.022.2-4.7-4.74.0-3.04.3-4.24.3-2.23.94.0-4.03.8-4.03.62.42.4-2.3-2.9-2.4-2.01.9-0.20.10.21.70.6
Reaction time number correct0.20.31.00.70.7-0.50.3-0.70.7-0.70.1-0.6-0.60.6-0.50.9-1.0-0.2-0.30.20.60.30.2-0.2-0.30.0-0.0-0.1-0.1
Reaction time mean minus median1.52.07.31.61.7-1.92.4-1.32.3-1.42.7-1.7-1.61.6-1.40.3-0.7-1.5-1.01.1-0.40.40.6-0.71.1-0.80.6-0.21.4
Reaction time mean minus median AUC0.81.13.61.31.5-1.41.5-1.11.9-1.31.7-1.6-1.51.5-1.00.6-1.0-0.8-0.50.50.00.20.2-0.30.4-0.2-0.10.00.6
Reaction time num false alarms0.40.64.6-0.2-0.70.7-1.60.0-1.10.0-2.1-0.00.1-0.1-0.10.5-0.80.80.3-0.41.60.30.10.1-0.80.9-0.5-0.4-0.4
Reaction time num false alarms AUC0.40.63.60.4-0.0-0.0-0.9-0.7-0.5-0.7-1.6-0.7-0.60.6-0.71.0-1.30.3-0.20.11.90.80.5-0.3-0.50.6-0.3-0.7-0.3
Reaction time trials correct on left0.20.31.00.70.7-0.50.3-0.70.7-0.70.1-0.6-0.60.6-0.50.9-1.0-0.2-0.30.20.60.30.2-0.2-0.30.0-0.0-0.1-0.1
Reaction time trials on left0.20.31.20.80.8-0.60.3-0.80.8-0.80.1-0.7-0.70.7-0.60.9-1.1-0.2-0.30.20.70.40.2-0.2-0.30.0-0.0-0.1-0.0
Reaction time mean0.20.21.0-0.3-0.10.00.40.40.70.10.90.10.1-0.10.4-0.40.00.20.4-0.4-1.0-0.7-0.60.60.1-0.0-0.50.80.4
Reaction time mean AUC0.20.31.2-0.3-0.10.10.40.50.60.21.00.10.2-0.20.4-0.40.10.20.5-0.4-1.1-0.8-0.70.60.1-0.1-0.50.80.5
Median of all reaction times0.20.31.1-0.7-0.50.40.10.80.10.40.50.50.5-0.50.7-0.70.30.30.5-0.5-1.1-0.8-0.60.60.1-0.1-0.50.7-0.0
Reaction time omissions0.50.72.60.80.7-0.90.6-0.61.2-1.20.7-1.6-1.51.5-0.90.7-1.4-0.3-0.20.20.50.20.1-0.10.1-0.2-0.30.00.9
Reaction time false alarm rate0.20.32.7-0.2-0.60.5-1.1-0.0-1.10.0-1.6-0.00.1-0.1-0.20.2-0.40.40.1-0.11.20.40.3-0.2-0.30.5-0.2-0.6-0.2
Reaction time premature initiation rate2.73.66.32.42.3-2.01.2-2.40.6-2.4-0.0-1.9-2.12.1-2.31.7-1.5-1.8-2.22.12.42.52.2-2.10.7-0.81.2-2.3-0.7
Reaction time premature initiations3.34.68.62.92.8-2.41.3-2.91.5-2.90.2-2.4-2.62.6-2.62.5-2.3-1.8-2.22.02.82.52.1-1.90.3-0.50.8-2.0-0.9
Std. dev. reaction times0.30.42.40.60.7-0.71.0-0.31.5-0.61.4-0.6-0.60.6-0.40.2-0.6-0.20.1-0.1-0.5-0.5-0.40.30.00.1-0.30.60.8
Reaction time trials completed0.20.31.20.80.8-0.60.3-0.80.8-0.80.1-0.7-0.70.7-0.60.9-1.1-0.2-0.30.20.70.40.2-0.2-0.30.0-0.0-0.1-0.0
Reaction time trials AUC0.20.20.80.60.6-0.50.2-0.70.5-0.7-0.0-0.6-0.60.6-0.50.7-0.9-0.2-0.30.20.70.40.3-0.2-0.2-0.10.1-0.20.1
Run reversals in cocaine runway, females2.22.15.50.80.6-1.10.7-1.0-1.1-0.8-0.3-1.2-1.21.2-1.5-0.60.4-1.7-2.02.01.42.22.2-2.21.7-1.72.0-2.30.6
Run reversals in cocaine runway, males0.10.10.4-0.10.50.3-0.5-0.1-0.3-0.0-0.50.40.4-0.40.10.20.10.40.4-0.30.2-0.2-0.20.2-0.1-0.1-0.50.10.6
Latency to leave start box in cocaine runway0.40.43.1-0.2-0.10.10.30.5-0.70.70.40.40.3-0.30.1-1.41.8-0.4-0.20.3-0.70.10.3-0.40.6-0.70.9-0.30.7
Latency to leave start box in cocaine runway, F0.10.10.50.10.1-0.00.30.10.10.30.40.1-0.00.00.1-0.70.5-0.1-0.00.1-0.4-0.1-0.0-0.0-0.1-0.00.30.1-0.3
Latency to leave start box in cocaine runway, M0.60.55.0-0.3-0.20.10.00.4-0.80.50.20.30.4-0.4-0.2-0.91.8-0.2-0.00.2-0.30.10.3-0.41.0-0.90.7-0.42.2
Std. dev. time between licks in bursts0.40.42.70.2-0.10.2-1.0-0.3-0.9-0.5-1.6-0.7-0.60.6-0.50.6-0.50.2-0.20.21.60.80.6-0.4-0.20.2-0.1-0.80.2
Total sessions with >9 infusions1.41.67.3-1.7-1.61.2-0.91.6-2.31.6-0.81.31.2-1.20.9-2.72.20.20.3-0.1-0.8-0.20.1-0.21.0-1.10.8-0.31.2
Short access day 1 total inactive lever presses3.03.36.9-2.6-2.62.4-2.02.4-2.42.3-1.72.52.5-2.52.2-1.91.81.51.4-1.3-1.2-1.3-1.11.1-0.60.4-0.40.9-0.6
Short access day 10 total inactive lever presses2.12.46.0-1.9-2.02.1-2.41.8-2.21.7-2.41.81.7-1.71.5-0.80.81.81.5-1.40.0-1.0-1.01.1-1.10.9-0.90.6-0.3
Short access day 1 total infusions2.12.27.0-2.1-2.21.7-1.22.0-2.41.9-0.91.91.9-1.91.5-2.62.10.70.7-0.6-1.2-0.7-0.40.30.6-0.60.60.20.6
Short access day 10 total infusions1.92.19.9-1.8-1.91.0-0.21.6-2.31.80.01.71.4-1.41.0-3.22.5-0.3-0.10.3-1.5-0.10.3-0.51.6-1.41.7-0.41.1
Short access total infusions1.41.57.0-1.6-1.71.0-0.51.5-2.21.5-0.41.41.2-1.20.8-2.62.1-0.0-0.00.1-1.0-0.00.3-0.41.3-1.21.3-0.41.2
Short access day 1 locomotion1.41.56.6-1.8-1.91.2-0.61.7-2.31.5-0.70.90.9-0.91.1-2.61.9-0.0-0.10.2-1.00.00.3-0.41.0-1.31.2-0.40.3
Short access day 10 total locomotion0.91.03.6-1.5-1.61.1-0.51.3-1.81.4-0.51.21.0-1.01.1-1.91.50.10.0-0.0-1.0-0.20.0-0.10.5-0.50.8-0.1-0.2
Short access total locomotion1.11.14.6-1.4-1.60.9-0.41.3-2.11.3-0.51.00.8-0.80.9-2.11.7-0.3-0.30.4-0.80.20.4-0.50.9-1.01.3-0.6-0.3
One hour access (0.3 mA shock)6.98.115.9-4.0-3.93.6-2.63.9-2.73.7-1.63.43.3-3.33.7-2.92.92.52.7-2.5-2.9-2.8-2.52.4-1.01.0-0.62.3-0.4
Compulsive drug intake2.72.88.12.21.9-1.50.3-2.11.2-2.3-0.8-2.2-2.02.0-2.02.8-2.3-0.6-1.10.92.81.71.2-1.0-0.50.6-0.5-1.3-1.1
One hour access (shock baseline)7.79.017.1-4.1-3.93.5-2.04.1-2.03.8-0.53.63.4-3.43.9-3.53.22.53.0-2.8-3.9-3.4-3.02.7-0.70.6-0.72.90.3
Social response proportion0.50.51.21.01.0-1.01.1-0.91.0-0.81.1-0.7-0.70.7-0.80.3-0.6-0.8-0.70.70.20.50.5-0.50.4-0.40.1-0.40.2
Social responses0.40.52.21.01.2-0.60.3-1.11.0-0.90.1-0.7-0.70.7-0.71.1-1.5-0.1-0.20.10.80.30.1-0.0-0.20.5-0.7-0.0-0.8
Social time0.30.41.10.91.0-0.70.3-1.00.6-1.00.1-0.8-0.80.8-0.90.8-1.1-0.2-0.30.30.80.40.3-0.30.20.0-0.2-0.30.1
Soleus weight2.36.812.7-3.4-3.13.6-3.33.3-3.23.3-2.83.23.2-3.23.0-2.21.92.82.7-2.5-1.4-2.2-2.12.1-1.21.4-1.21.7-0.2
Bone: stiffness1.82.98.91.51.6-2.22.8-1.31.5-1.23.0-1.2-1.31.3-1.5-0.60.4-2.3-1.91.9-0.71.21.5-1.62.1-2.02.0-1.11.4
Tibialis anterior weight6.622.639.76.26.3-6.35.9-5.95.3-5.84.9-5.8-5.85.8-5.43.5-3.5-5.1-5.04.72.54.24.1-4.02.6-2.62.2-3.3-0.7
Time to tail flick, vehicle, before self-admin1.61.63.40.70.7-1.21.7-0.60.0-0.51.6-0.8-0.90.9-0.9-0.91.2-1.7-1.51.6-0.51.11.4-1.51.8-1.81.8-1.21.8
Time to tail flick, vehicle, after self-admin3.94.26.52.02.0-2.21.8-2.10.2-2.01.1-2.1-2.12.1-2.50.10.3-2.4-2.42.51.42.52.5-2.62.3-2.42.0-2.52.1
Time to tail flick, test, before self-admin0.90.93.6-0.7-0.60.3-0.20.6-1.90.5-0.60.10.2-0.20.1-1.31.4-0.6-0.80.8-0.00.91.0-1.01.4-1.51.7-1.21.1
Time to tail flick, test, after self-admin0.10.10.30.20.2-0.30.2-0.40.2-0.30.2-0.5-0.40.4-0.40.3-0.2-0.2-0.10.20.20.20.2-0.20.3-0.5-0.2-0.10.4
Delta time to tail flick, vehicle, before/after SA0.90.91.91.11.1-1.00.6-1.30.1-1.10.1-1.0-0.90.9-1.40.4-0.3-0.9-1.01.01.21.21.1-1.10.8-1.00.4-1.20.8
Delta time to tail flick, test, before/after SA1.31.14.81.00.9-0.60.4-1.02.2-0.90.6-0.7-0.70.7-0.41.8-1.70.50.6-0.60.4-0.6-0.80.9-1.41.4-1.71.0-1.3
Tibia length0.51.39.41.00.9-1.52.5-0.72.5-0.63.1-0.5-0.50.5-0.30.3-0.3-1.3-0.70.7-1.6-0.2-0.0-0.10.5-0.40.50.6-0.3
Ambulatory time before self-admin0.30.32.50.20.3-0.41.10.11.30.11.6-0.2-0.20.20.30.1-0.4-0.4-0.10.0-1.2-0.5-0.40.30.10.10.30.7-0.5
Ambulatory time after self-admin0.40.41.6-0.7-0.50.40.20.80.20.80.60.80.8-0.80.9-0.30.60.30.5-0.5-1.3-0.8-0.70.6-0.10.2-0.10.8-0.3
Bone: tissue strength0.20.20.4-0.2-0.30.20.00.30.40.30.40.30.4-0.40.4-0.1-0.10.30.4-0.5-0.5-0.6-0.60.5-0.40.3-0.40.7-0.5
Total heroin consumption3.33.87.32.62.4-2.62.2-2.52.6-2.61.9-2.7-2.62.6-2.32.2-2.5-1.6-1.51.51.31.41.2-1.20.7-0.60.2-0.90.4
Bone: trabecular number0.71.14.10.40.2-1.01.8-0.30.6-0.22.0-0.4-0.30.3-0.4-1.00.8-1.5-1.11.2-1.10.50.8-0.91.5-1.51.5-0.51.4
Bone: trabecular spacing0.50.62.9-0.10.00.7-1.4-0.0-0.5-0.0-1.70.20.2-0.20.10.9-0.91.00.7-0.81.2-0.2-0.40.6-1.21.1-0.80.2-1.3
Bone: trabecular thickness0.50.61.5-1.0-1.20.8-0.31.1-0.81.20.10.91.0-1.00.9-1.21.10.30.5-0.4-1.1-0.6-0.40.30.4-0.3-0.00.41.2
Bone: trabecular tissue density2.73.96.2-2.3-2.22.5-2.32.2-1.32.2-1.72.12.2-2.22.1-0.90.62.42.5-2.4-1.0-2.2-2.22.2-1.61.7-1.72.00.0
Water consumed over 24 hours0.70.93.31.21.3-0.80.3-1.21.3-1.30.0-1.1-1.11.1-0.71.8-1.3-0.1-0.30.11.00.40.1-0.0-0.90.9-0.7-0.0-1.0
Number of responses in last shaping day0.80.82.4-1.2-1.41.2-1.41.1-1.10.7-1.50.90.9-0.91.0-0.0-0.60.90.6-0.80.1-0.4-0.60.6-0.60.5-0.50.4-1.4