Hub : Genes

Ganab

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA isoform ratio NM_001398785.1 0.05 0.04 1.6e-05 0.06 0.05 0.05 0.05 1.8e-05 8.7e-05 1.1e-04 4.5e-05
2 NAcc gene expression Ganab 0.03 0.02 7.3e-05 0.02 0.03 0.02 0.02 1.3e-04 5.3e-05 2.1e-04 2.8e-04
3 PL gene expression Ganab 0.04 0.02 2.5e-06 0.06 0.06 0.04 0.06 3.6e-07 1.0e-06 2.2e-05 6.9e-07
4 BLA gene expression Ganab 0.12 0.07 2.1e-06 0.09 0.09 0.1 0.09 1.3e-05 1.3e-05 5.3e-06 1.4e-05
5 IC intron excision ratio chr1_215223064_215226988 0.19 0.1 5.3e-08 0.14 0.16 0.09 0.16 1.5e-06 2.2e-07 1.2e-04 2.5e-07
6 Brain isoform ratio NM_001398784.1 0.06 0.04 5.9e-07 0.08 0.06 0.06 0.07 1.3e-07 4.8e-06 1.8e-06 7.2e-07
7 Brain isoform ratio NM_001398785.1 0.06 0.04 6.4e-07 0.08 0.06 0.06 0.07 6.0e-08 4.0e-06 1.4e-06 1.9e-07
8 NAcc intron excision ratio chr1_215223584_215226988 0.09 0.05 0.0e+00 0.14 0.14 0.14 0.14 8.4e-21 1.6e-20 1.6e-20 3.2e-20
9 PL intron excision ratio chr1_215223064_215226988 0.15 0.09 0.0e+00 0.2 0.18 0.19 0.19 3.6e-21 3.7e-19 2.3e-20 9.5e-21
10 NAcc intron excision ratio chr1_215223064_215226988 0.09 0.05 0.0e+00 0.15 0.14 0.14 0.14 1.8e-21 4.5e-21 4.0e-21 4.7e-21
11 IC gene expression Ganab 0.11 0.07 2.6e-04 0.02 0.02 0.04 0.02 6.2e-02 5.7e-02 7.7e-03 3.9e-02
12 Brain gene expression Ganab 0.09 0.05 1.9e-10 0.1 0.11 0.1 0.1 2.2e-09 3.1e-10 2.2e-09 8.9e-10
13 Liver gene expression Ganab 0.28 0.17 2.1e-09 0.07 0.06 0.06 0.07 6.0e-08 9.2e-08 1.2e-07 6.7e-08
14 NAcc isoform ratio NM_001398785.1 0.01 0.01 5.3e-03 0.01 0.01 0.01 0.01 1.8e-02 4.5e-03 8.1e-03 1.1e-02
15 IC intron excision ratio chr1_215223584_215226988 0.23 0.11 5.5e-09 0.16 0.18 0.17 0.18 2.1e-07 3.6e-08 8.3e-08 5.9e-08
16 NAcc isoform ratio NM_001398784.1 0.02 0.02 2.5e-04 0.02 0.03 0.03 0.03 1.2e-03 7.0e-05 5.4e-05 7.3e-05
17 Adipose isoform ratio NM_001398784.1 0.03 0.02 9.6e-03 -0 0 0 -0 3.9e-01 1.5e-01 8.2e-02 4.9e-01
18 pVTA gene expression Ganab 0.15 0.08 1.8e-15 0.17 0.19 0.18 0.18 4.9e-14 5.1e-15 7.8e-15 1.3e-14
19 pVTA isoform ratio NM_001398784.1 0.05 0.04 9.8e-05 0.03 0.03 0.03 0.03 3.2e-03 1.6e-03 3.2e-03 1.8e-03
20 pVTA intron excision ratio chr1_215233340_215234658 0.03 0.02 4.4e-03 0.01 0.01 0 0 6.2e-02 7.9e-02 1.2e-01 1.1e-01
21 Brain intron excision ratio chr1_215233340_215234658 0.09 0.06 7.3e-08 0.06 0.06 0.07 0.08 1.8e-06 1.3e-06 3.5e-07 9.5e-08
22 Brain intron excision ratio chr1_215233879_215234658 0.05 0.03 1.0e-04 0.01 0.03 0.04 0.03 1.8e-02 1.2e-03 3.0e-04 6.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.40.71.80.70.40.60.70.7-0.80.8-0.80.70.81.30.7-0.71.0-0.5-1.3-0.91.0-1.10.50.6-0.7
Area under the delay curve0.10.10.40.1-0.30.10.10.1-0.10.1-0.10.10.10.30.2-0.20.3-0.1-0.40.60.4-0.40.40.10.1
BMI with tail2.38.116.72.81.52.72.72.5-2.82.8-2.72.72.63.92.6-2.83.4-2.1-4.1-1.33.6-3.82.72.6-2.1
BMI without tail0.41.32.91.30.31.21.11.0-1.01.0-1.01.00.91.21.2-1.21.4-1.0-1.40.41.5-1.71.61.0-0.5
Body weight3.113.719.54.02.84.03.83.6-3.83.8-3.73.73.64.13.7-3.84.2-3.4-4.2-1.44.3-4.43.93.4-2.8
Weight adjusted by age0.71.11.71.11.01.11.11.0-1.11.1-1.11.01.11.31.0-1.01.1-0.9-1.1-1.11.1-1.10.90.8-1.1
Bone surface2.54.67.72.11.82.12.12.0-2.22.2-2.22.12.12.81.9-2.02.4-1.7-2.6-2.02.3-2.31.62.0-2.2
Bone volume1.22.14.71.31.11.31.31.2-1.41.4-1.41.31.42.21.1-1.31.6-0.9-2.0-1.91.6-1.60.81.3-1.5
Breakpoint value in progressive ratio session2.22.74.51.72.11.71.81.8-1.71.7-1.71.71.71.21.7-1.71.5-1.9-1.1-1.41.4-1.31.31.8-1.8
Number of licking bursts0.00.00.10.2-0.10.20.1-0.00.0-0.0-0.1-0.1-0.00.10.00.10.00.00.0-0.20.0-0.10.2-0.00.2
Context. condit. distance diff. score0.40.41.1-0.9-1.1-0.9-0.8-0.70.7-0.70.7-0.5-0.7-0.3-0.60.5-0.40.60.11.0-0.30.2-0.5-0.50.7
Locomotion velocity, session 10.10.11.9-0.3-0.4-0.3-0.2-0.10.1-0.10.10.1-0.1-0.30.1-0.1-0.0-0.00.01.40.1-0.20.4-0.20.4
Locomotion distance, session 10.50.61.20.50.20.40.50.7-0.60.6-0.61.00.60.70.8-0.90.9-0.7-1.10.91.0-1.11.00.9-0.6
Locomotion velocity, session 22.52.94.11.81.61.71.71.7-1.61.6-1.72.01.61.61.8-2.01.9-1.8-1.9-0.41.9-1.91.71.8-1.7
Locomotion distance, session 20.20.20.70.40.20.30.40.5-0.30.3-0.30.60.30.10.6-0.60.4-0.6-0.30.80.5-0.60.70.5-0.2
Locomotion velocity, session 30.30.41.50.5-0.20.40.40.4-0.30.3-0.40.50.41.00.5-0.50.8-0.2-1.20.10.9-1.10.80.4-0.2
Locomotion distance, session 30.10.10.60.3-0.10.30.20.2-0.20.2-0.20.10.10.00.3-0.20.2-0.1-0.10.80.2-0.30.6-0.10.1
Stereotopy head waving bouts, day 30.20.20.8-0.6-0.9-0.6-0.6-0.50.5-0.50.6-0.2-0.50.4-0.40.2-0.00.5-0.60.20.1-0.3-0.5-0.10.3
Stereotopy head waving duration, day 30.10.20.5-0.6-0.7-0.6-0.5-0.40.5-0.50.5-0.1-0.50.1-0.30.1-0.10.3-0.30.60.1-0.1-0.40.10.3
Locomotion velocity, session 70.00.00.3-0.1-0.2-0.2-0.2-0.10.2-0.20.20.1-0.20.4-0.1-0.10.20.1-0.5-0.00.2-0.3-0.20.1-0.0
Locomotion distance, session 70.10.10.8-0.4-0.7-0.3-0.4-0.30.4-0.40.4-0.2-0.4-0.0-0.20.2-0.10.3-0.20.90.0-0.20.1-0.30.4
Stereotopy head waving bouts, day 70.30.31.10.40.50.40.40.4-0.40.4-0.40.50.40.80.3-0.50.6-0.3-0.8-1.10.5-0.5-0.00.8-0.6
Stereotopy head waving duration, day 71.61.92.61.41.41.41.41.4-1.41.4-1.41.41.41.51.3-1.41.5-1.3-1.4-1.21.5-1.41.11.6-1.3
Locomotion velocity, session 80.20.22.5-0.4-0.4-0.4-0.4-0.20.3-0.30.4-0.0-0.3-0.8-0.0-0.0-0.3-0.10.51.6-0.20.20.2-0.30.5
Locomotion distance, session 80.30.41.2-0.8-1.1-0.9-0.8-0.70.8-0.80.8-0.5-0.80.0-0.60.5-0.30.7-0.30.6-0.20.1-0.6-0.30.4
Degree of sensitization distance0.10.10.7-0.3-0.6-0.2-0.3-0.20.2-0.20.2-0.1-0.20.7-0.20.10.20.3-0.8-0.30.3-0.4-0.20.00.1
Degree of sensitization stereotypy1.21.32.61.01.21.11.11.0-1.01.0-1.11.11.11.30.9-1.11.1-0.9-1.3-1.61.0-1.00.51.4-1.2
Conditioned locomotion0.50.60.70.80.70.80.80.8-0.90.9-0.80.80.80.60.9-0.80.8-0.8-0.50.00.8-0.80.80.6-0.2
Cocaine response after cond. corrected0.70.94.0-1.2-1.2-1.2-1.1-0.80.7-0.70.9-0.7-0.9-1.0-0.70.7-0.80.70.72.0-0.70.6-0.4-0.70.9
Cocaine response after cond. not corrected0.40.51.6-0.9-1.0-0.9-0.8-0.70.6-0.60.7-0.5-0.7-0.7-0.60.5-0.60.70.41.3-0.50.5-0.4-0.50.5
Cocaine response before conditioning0.50.63.40.91.00.90.80.6-0.70.7-0.70.70.80.70.5-0.70.6-0.5-0.8-1.80.5-0.40.30.6-1.2
Saline control response2.63.55.82.21.72.22.02.0-1.91.9-1.92.01.81.22.1-2.11.9-2.0-1.30.51.9-1.92.41.9-1.4
Bone: connectivity density1.93.04.71.71.31.61.71.7-1.81.8-1.81.71.82.11.6-1.72.0-1.5-2.2-1.12.0-2.01.51.5-1.6
Bone: cortical apparent density0.20.30.80.40.90.40.50.7-0.70.7-0.60.70.6-0.00.7-0.70.4-0.80.00.20.3-0.20.30.8-0.8
Bone: cortical area1.01.62.21.41.21.41.31.1-1.21.2-1.21.31.21.51.0-1.21.3-1.0-1.4-1.31.2-1.21.01.3-1.5
Bone: cortical porosity0.10.10.4-0.20.4-0.2-0.10.00.1-0.10.1-0.0-0.1-0.5-0.00.0-0.3-0.20.60.2-0.40.4-0.40.2-0.1
Bone: cortical porosity0.10.10.20.00.50.00.10.2-0.10.1-0.10.20.1-0.40.2-0.2-0.1-0.40.40.4-0.10.2-0.00.4-0.2
Bone: cortical thickness2.84.76.82.52.52.52.52.5-2.32.3-2.32.42.31.02.5-2.42.0-2.6-1.00.11.9-1.82.62.0-1.9
Bone: cortical thickness0.30.41.00.60.60.60.70.7-0.70.7-0.70.70.7-0.20.8-0.60.4-0.80.11.00.5-0.40.90.4-0.3
Bone: cortical tissue density0.40.51.20.61.10.60.70.9-0.80.8-0.70.90.80.10.8-0.90.5-1.0-0.10.20.5-0.30.51.0-0.9
Condit. Reinf. active minus inactive responses1.11.21.51.11.11.01.21.2-1.21.2-1.21.21.21.11.1-1.21.2-1.1-1.1-0.71.1-1.11.00.9-1.0
Condit. Reinf. active-inactive response ratio0.40.40.70.60.80.50.70.8-0.80.8-0.80.70.80.40.8-0.70.6-0.8-0.30.10.6-0.60.60.6-0.5
Condit. Reinf. active responses1.11.42.51.11.11.01.11.1-1.11.1-1.21.21.21.61.0-1.21.3-0.9-1.6-1.61.2-1.20.60.9-1.3
Condit. Reinf. inactive responses0.20.32.90.1-0.10.10.0-0.10.1-0.1-0.00.00.01.0-0.2-0.00.30.3-1.0-1.70.2-0.3-0.4-0.1-0.4
Incentive salience index mean1.41.72.61.31.01.31.31.3-1.31.3-1.31.41.31.51.2-1.31.5-1.1-1.6-0.91.4-1.51.21.0-1.3
Condit. Reinf. lever presses1.01.43.21.20.81.31.21.0-1.11.1-1.11.21.11.61.0-1.21.4-0.8-1.8-1.01.4-1.41.01.0-1.3
Condit. Reinf. active minus inactive responses0.10.10.7-0.20.1-0.3-0.3-0.30.3-0.30.4-0.3-0.3-0.1-0.50.3-0.30.40.0-0.8-0.40.5-0.70.2-0.6
Condit. Reinf. active-inactive response ratio0.50.63.0-0.7-0.4-0.7-0.7-0.70.7-0.70.7-0.6-0.70.3-0.90.6-0.40.9-0.4-1.7-0.50.5-1.40.1-0.5
Condit. Reinf. active responses0.10.10.50.40.50.40.30.3-0.30.3-0.20.30.30.20.2-0.30.3-0.3-0.2-0.30.2-0.20.20.6-0.7
Condit. Reinf. inactive responses0.20.31.50.60.30.60.50.5-0.60.6-0.40.40.5-0.40.6-0.40.3-0.60.41.20.3-0.31.1-0.00.3
Condit. Reinf. lever presses1.11.52.11.41.11.41.31.1-1.31.3-1.31.11.21.51.0-1.11.3-0.9-1.3-1.21.2-1.21.01.1-1.3
Condit. Reinf. lever reinforcers received0.20.30.80.70.80.60.60.6-0.60.6-0.50.60.50.30.5-0.60.5-0.5-0.4-0.40.4-0.30.40.8-0.9
Conditioned reinforcement - actives0.20.43.6-0.60.1-0.6-0.4-0.40.6-0.60.3-0.4-0.40.3-0.60.4-0.30.6-0.1-1.9-0.40.5-1.0-0.1-0.4
Conditioned reinforcement - inactives0.20.33.1-0.3-0.1-0.3-0.1-0.20.2-0.20.0-0.1-0.11.1-0.40.10.20.5-0.9-1.80.1-0.1-0.70.1-0.6
Conditioned locomotion1.92.43.8-1.9-1.9-1.9-1.8-1.81.7-1.71.6-1.6-1.7-0.6-1.81.6-1.31.90.50.2-1.31.2-1.8-1.51.2
Patch foraging indifference point 0 sec0.40.81.30.90.80.90.90.9-0.90.9-0.80.90.90.80.9-0.91.0-0.9-0.80.41.0-1.01.01.1-1.0
Patch foraging indifference point AUC1.52.14.21.42.01.41.51.5-1.51.5-1.41.51.51.41.3-1.51.4-1.4-1.2-2.01.2-1.10.61.5-1.6
Delay disc. indifference point, 0s delay0.40.41.4-0.7-1.2-0.7-0.7-0.70.7-0.70.7-0.7-0.7-0.2-0.60.6-0.40.70.11.1-0.20.1-0.2-0.70.8
Delay disc. indifference point, 16s delay0.10.20.60.30.20.40.30.3-0.30.3-0.30.30.30.70.2-0.30.5-0.1-0.8-0.50.5-0.50.20.3-0.4
Delay disc. indifference point, 2s delay0.20.20.6-0.5-0.8-0.5-0.5-0.60.5-0.50.5-0.5-0.50.1-0.60.4-0.30.7-0.2-0.1-0.20.2-0.5-0.50.4
Delay disc. indifference point, 24s delay0.10.10.50.3-0.00.20.20.3-0.30.3-0.30.30.30.10.4-0.30.3-0.3-0.10.70.4-0.40.60.10.1
Delay disc. indifference point, 4s delay0.30.31.40.4-0.10.40.40.4-0.40.4-0.40.40.40.40.6-0.50.6-0.5-0.51.20.7-0.81.00.4-0.0
Delay disc. indifference point, 8s delay0.40.52.0-0.7-0.8-0.7-0.7-0.60.7-0.70.7-0.7-0.7-0.8-0.50.7-0.70.50.81.4-0.50.5-0.2-0.60.8
Indifference point function ln k3.25.611.9-2.5-3.1-2.5-2.5-2.42.2-2.22.3-2.3-2.3-2.2-2.12.3-2.22.31.93.5-1.91.8-1.3-2.42.6
Indifference point function log k3.25.611.9-2.5-3.1-2.5-2.5-2.42.2-2.22.3-2.3-2.3-2.2-2.12.3-2.22.31.93.5-1.91.8-1.3-2.42.6
Patch foraging total patch changes 0 sec0.40.81.40.90.80.90.90.9-0.90.9-0.81.00.90.41.0-0.90.9-1.0-0.51.00.9-0.91.21.0-0.8
Patch foraging total patch changes 12 sec6.28.010.62.93.33.02.93.1-3.03.0-2.93.12.92.23.0-3.12.8-3.1-2.3-1.22.7-2.62.53.1-3.0
Patch foraging total patch changes 18 sec0.50.81.60.91.31.00.91.0-1.01.0-0.81.00.90.50.9-1.00.8-1.0-0.5-0.50.7-0.70.61.1-1.2
Patch foraging total patch changes 24 sec4.88.210.03.02.73.03.03.0-3.23.2-2.93.02.92.73.0-2.83.0-2.9-2.7-1.03.0-3.02.82.9-2.5
Patch foraging total patch changes 6 sec1.21.82.31.41.21.41.31.4-1.51.5-1.31.41.31.11.4-1.31.4-1.4-1.20.21.4-1.51.41.4-1.1
Patch foraging time to switch 0 sec0.30.72.60.60.60.60.60.6-0.50.5-0.60.80.61.30.5-0.81.0-0.5-1.4-1.60.9-0.90.20.8-1.0
Patch foraging water rate 0 sec0.40.92.5-0.8-0.9-0.9-0.8-0.80.7-0.70.7-0.9-0.7-1.2-0.80.9-1.00.81.31.6-1.01.0-0.4-0.91.0
Patch foraging water rate 12 sec1.83.77.4-1.7-2.2-1.7-1.8-1.81.7-1.71.7-2.0-1.8-2.2-1.62.0-1.91.72.22.7-1.81.7-0.7-2.22.4
Patch foraging water rate 18 sec0.71.16.4-0.7-1.6-0.7-0.8-0.90.8-0.80.7-1.0-0.8-1.1-0.61.1-0.80.90.92.5-0.60.50.3-1.21.5
Patch foraging water rate 24 sec1.52.03.9-1.5-1.6-1.4-1.5-1.41.4-1.41.4-1.3-1.4-1.6-1.31.4-1.51.31.42.0-1.41.4-0.9-1.51.5
Patch foraging water rate 6 sec1.82.77.3-1.4-1.9-1.4-1.5-1.51.5-1.51.5-1.6-1.5-1.9-1.31.7-1.71.41.92.7-1.51.4-0.6-1.82.0
Seeking ratio, delayed vs. immediate footshock0.00.00.10.20.00.30.20.2-0.20.2-0.20.20.20.30.2-0.20.2-0.1-0.30.10.3-0.30.30.1-0.1
Distance traveled before self-admin2.43.14.51.71.81.81.81.7-1.81.8-1.81.81.82.11.6-1.71.9-1.5-2.0-1.91.8-1.71.21.8-1.8
Distance traveled after self-admin0.50.61.20.81.10.70.80.9-0.90.9-0.90.71.00.60.8-0.60.7-0.8-0.3-0.70.6-0.50.50.9-0.8
Extensor digitorum longus weight6.224.529.25.44.55.45.35.1-5.25.2-5.35.05.14.75.2-5.05.3-4.9-4.5-1.75.3-5.35.24.8-4.1
Bone: elastic displacement0.60.72.0-0.6-0.5-0.7-0.6-0.60.6-0.60.6-0.7-0.6-1.3-0.50.7-0.90.41.41.2-0.80.9-0.2-0.91.3
Bone: elastic work0.81.02.41.10.81.01.11.1-1.11.1-1.11.11.10.31.3-1.00.9-1.2-0.21.01.0-1.01.50.50.0
Bone: endosteal estimation0.81.84.0-1.4-2.0-1.3-1.5-1.61.3-1.31.4-1.4-1.40.5-1.71.5-0.82.0-0.6-1.0-0.70.5-1.6-1.11.0
Bone: endosteal perimeter1.32.86.0-1.7-2.1-1.7-1.8-2.01.7-1.71.8-1.8-1.80.5-2.21.9-1.12.4-0.5-1.8-1.10.9-2.3-1.20.9
Epididymis fat weight0.51.74.1-1.1-1.7-1.0-1.3-1.61.3-1.31.4-1.6-1.50.3-1.81.5-0.92.0-0.2-1.5-0.90.8-1.5-1.00.5
Delta time in closed arm before/after self-admin1.00.93.30.80.30.80.80.9-0.80.8-0.81.00.90.21.2-0.90.9-1.1-0.51.81.1-1.21.60.6-0.1
Delta time in open arm before/after self-admin2.52.55.31.41.81.41.51.5-1.51.5-1.51.71.41.81.3-1.71.6-1.4-1.8-2.31.4-1.30.71.7-1.9
Diff in mean of infusions in LGA sessions2.22.73.81.61.91.61.71.9-1.71.7-1.71.91.71.11.9-1.81.6-2.0-1.2-0.31.6-1.51.61.8-1.5
Delay discount exponential model param0.10.10.3-0.10.2-0.1-0.1-0.10.1-0.10.1-0.1-0.1-0.3-0.20.2-0.30.10.4-0.5-0.40.5-0.4-0.1-0.0
Extinction: sum of active levers before priming4.04.44.92.22.02.12.22.1-2.22.2-2.22.22.22.12.1-2.02.2-2.0-2.1-1.02.2-2.22.02.2-2.0
Active lever presses in extinction session 63.43.34.51.82.11.81.81.9-1.81.8-1.82.01.81.91.7-2.01.8-1.7-1.8-2.01.7-1.61.21.8-2.0
Bone: final force1.82.94.41.81.41.71.71.6-1.61.6-1.71.81.72.11.5-1.71.9-1.4-2.1-1.31.8-1.91.51.7-1.9
Bone: final moment1.93.04.31.81.41.81.71.6-1.71.7-1.71.81.72.01.6-1.71.9-1.4-2.1-1.21.9-1.91.61.7-1.9
Food consumed during 24 hour testing period0.10.10.20.0-0.10.0-0.1-0.30.2-0.20.1-0.5-0.2-0.2-0.40.5-0.30.40.4-0.1-0.40.4-0.2-0.30.1
Glucose2.23.56.0-1.9-2.4-1.9-2.0-2.11.9-1.92.0-2.2-2.0-0.9-2.12.2-1.72.31.00.7-1.61.4-1.7-2.01.9
Heart weight0.30.42.2-0.4-1.5-0.6-0.6-0.70.5-0.50.7-0.8-0.6-0.0-0.50.7-0.20.9-0.21.1-0.0-0.20.2-0.60.8
Delay discount hyperbolic model param0.00.00.2-0.00.3-0.0-0.0-0.00.0-0.00.0-0.0-0.0-0.3-0.10.1-0.20.00.4-0.5-0.30.4-0.3-0.0-0.1
Intermittent access intake day 1-15 change0.91.93.0-1.3-0.9-1.4-1.4-1.51.4-1.41.6-1.4-1.5-0.9-1.71.4-1.41.51.1-0.9-1.61.7-1.7-1.00.5
Intermittent access intake escalation1.12.33.7-1.5-0.9-1.5-1.6-1.61.6-1.61.7-1.5-1.7-1.0-1.81.6-1.61.71.3-1.0-1.81.9-1.9-1.10.5
Intermittent access intake escalation 20.50.61.4-0.7-0.2-0.7-0.7-0.80.8-0.80.8-0.7-0.8-0.2-1.00.7-0.70.90.3-1.2-0.80.9-1.1-0.3-0.2
Intermitt. access day 1 inactive lever presses0.41.32.1-1.3-0.7-1.2-1.2-1.21.4-1.41.3-1.1-1.3-1.0-1.31.0-1.21.11.0-0.3-1.31.4-1.4-0.80.5
Intermitt. access day 15 inactive lever presses0.61.24.30.90.70.90.80.7-0.80.8-0.80.90.92.00.5-0.91.2-0.4-1.8-2.11.2-1.10.41.0-1.4
Intermitt. access escalation Index0.71.01.5-1.0-1.1-0.9-1.0-1.00.9-0.91.0-1.0-1.0-1.2-0.91.0-1.00.91.21.2-1.01.0-0.8-1.11.2
Intermittent access day 1 total infusions0.40.62.2-0.8-1.5-0.7-0.8-0.90.8-0.80.7-0.5-0.71.0-0.90.70.01.2-1.2-0.50.2-0.3-0.8-0.60.4
Intermittent access day 15 total infusions2.53.86.6-2.1-2.2-2.1-2.2-2.32.2-2.22.2-2.0-2.1-0.4-2.52.2-1.62.60.5-1.0-1.61.7-2.4-1.71.0
Intermittent access terminal intake (last 3 days)0.91.22.7-1.1-1.3-1.1-1.2-1.31.1-1.11.1-0.9-1.10.9-1.51.1-0.41.6-0.9-1.6-0.40.4-1.5-0.70.1
Intermittent access total infusions1.01.22.6-1.2-1.5-1.2-1.2-1.31.2-1.21.1-1.0-1.10.7-1.41.1-0.51.6-0.7-1.0-0.40.4-1.3-0.90.4
Intermittent access day 1 locomotion0.20.21.3-0.4-0.9-0.4-0.4-0.40.3-0.30.3-0.1-0.30.9-0.40.10.30.6-1.2-0.30.4-0.5-0.3-0.20.1
Intermittent access day 15 total locomotion0.20.42.2-0.6-0.5-0.6-0.5-0.50.4-0.40.4-0.2-0.41.2-0.70.30.20.8-1.2-1.50.2-0.1-0.9-0.0-0.4
Intermittent access total locomotion0.60.83.5-0.6-0.9-0.6-0.6-0.60.5-0.50.4-0.2-0.41.8-0.80.30.41.1-1.9-1.70.4-0.5-1.0-0.0-0.5
Intermittent access standard deviation0.51.01.5-1.1-0.8-1.1-1.1-1.11.1-1.11.2-1.0-1.1-0.5-1.21.1-1.01.20.6-0.5-1.01.1-1.2-0.90.5
Left kidney weight0.10.41.2-0.4-1.0-0.5-0.6-0.80.6-0.60.7-0.7-0.70.6-0.80.7-0.21.0-0.6-1.1-0.10.0-0.7-0.20.1
Right kidney weight0.10.21.2-0.2-0.6-0.2-0.4-0.50.4-0.40.4-0.6-0.50.4-0.60.5-0.10.8-0.4-1.1-0.10.0-0.5-0.10.0
Cocaine induced anxiety0.10.10.60.10.60.10.20.3-0.10.1-0.20.20.20.20.1-0.40.2-0.3-0.1-0.80.1-0.0-0.10.3-0.6
Post-drug Anxiety0.40.40.60.60.80.60.70.7-0.60.6-0.70.50.70.70.6-0.80.6-0.6-0.5-0.70.6-0.50.40.6-0.7
Baseline Anxiety0.30.40.90.60.20.60.70.6-0.60.6-0.70.50.70.30.7-0.50.6-0.6-0.40.70.7-0.70.90.30.0
Tail length0.31.02.41.31.11.41.21.1-1.01.0-1.00.90.9-0.11.2-1.00.7-1.30.10.80.7-0.71.60.8-0.5
Length with tail1.25.48.02.82.32.82.62.5-2.52.5-2.42.42.41.62.6-2.32.3-2.5-1.6-0.42.3-2.32.82.2-1.8
Length without tail2.78.711.33.32.83.33.23.1-3.23.2-3.13.03.02.43.2-2.93.0-3.1-2.4-0.53.0-3.03.42.8-2.3
Times rat made contact with spout0.20.21.40.40.30.40.30.3-0.30.3-0.30.10.3-0.40.4-0.10.1-0.50.61.20.1-0.10.80.30.1
Lifetime Intake0.80.92.4-1.1-1.6-1.1-1.1-1.21.1-1.11.0-0.9-1.00.4-1.21.0-0.51.4-0.5-0.4-0.30.3-1.0-0.90.7
Liver weight, left1.11.92.5-1.3-1.3-1.3-1.4-1.41.3-1.31.4-1.5-1.5-1.4-1.41.5-1.51.41.40.7-1.51.4-1.2-1.61.4
Liver weight, right1.52.64.5-1.5-2.1-1.5-1.7-1.81.6-1.61.7-1.7-1.7-1.4-1.61.7-1.51.81.21.6-1.41.3-0.9-1.71.8
Locomotor activity1.11.86.6-1.1-1.3-1.1-1.1-1.11.1-1.11.1-1.3-1.2-1.8-0.81.2-1.30.91.82.6-1.21.1-0.2-1.51.8
Locomotor testing distance1.22.18.4-1.2-1.6-1.3-1.2-1.21.2-1.21.3-1.3-1.2-1.8-0.91.2-1.41.01.72.9-1.21.1-0.2-1.81.9
Locomotor testing rearing1.02.05.0-1.2-1.6-1.2-1.3-1.31.3-1.31.4-1.4-1.2-1.7-1.11.3-1.41.21.62.2-1.31.2-0.4-1.81.9
Locomotion in novel chamber1.72.23.4-1.7-1.6-1.7-1.6-1.71.6-1.61.6-1.7-1.6-0.7-1.71.5-1.31.80.7-0.2-1.31.3-1.8-1.51.1
Locomotion in novel chamber post-restriction1.62.64.3-1.8-1.4-1.9-1.8-1.71.7-1.71.8-1.8-1.8-1.2-1.81.7-1.71.71.3-0.2-1.71.7-2.1-1.11.0
Fecal boli incidents, locomotor time 10.20.32.2-0.4-0.0-0.4-0.4-0.40.4-0.40.4-0.4-0.40.1-0.60.4-0.40.6-0.0-1.5-0.50.6-1.0-0.2-0.2
Change in fecal boli incidents, locomotor task1.41.43.8-1.2-1.5-1.2-1.2-1.21.2-1.21.2-1.2-1.2-1.2-1.01.1-1.11.01.11.9-1.00.9-0.5-1.11.3
Time >=10cm from walls, locomotor time 11.61.74.3-1.4-1.2-1.4-1.4-1.51.5-1.51.3-1.3-1.3-0.1-1.71.4-1.11.70.1-1.3-1.11.2-2.1-0.90.4
Bouts of movement, locomotor time 10.30.31.80.31.30.20.50.6-0.20.2-0.50.50.5-0.40.5-0.60.0-0.90.6-0.5-0.20.3-0.10.5-0.7
Total resting periods, locomotor time 10.20.31.50.31.20.30.50.6-0.30.3-0.50.50.5-0.20.4-0.60.1-0.70.4-0.8-0.10.2-0.10.5-0.7
Rest time, locomotor task time 11.51.92.7-1.3-1.1-1.4-1.4-1.41.2-1.21.5-1.5-1.5-1.4-1.51.5-1.61.41.50.2-1.61.6-1.4-1.21.0
Distance moved, locomotor task time 10.20.40.70.60.30.60.60.6-0.60.6-0.60.60.60.80.6-0.60.7-0.5-0.9-0.00.8-0.80.60.4-0.3
Vertical activity count, locomotor time 10.20.50.7-0.8-0.8-0.8-0.8-0.80.8-0.80.7-0.7-0.7-0.6-0.70.7-0.70.70.50.6-0.60.6-0.6-0.70.7
Time >=10cm from walls, locomotor time 20.10.11.8-0.10.3-0.1-0.1-0.10.1-0.10.1-0.1-0.10.2-0.30.1-0.20.2-0.1-1.3-0.30.4-0.80.1-0.4
Bouts of movement, locomotor time 20.81.31.81.31.31.31.31.3-1.31.3-1.21.21.20.91.2-1.21.1-1.3-0.8-0.61.1-1.01.11.0-1.0
Total resting periods, locomotor time 20.30.60.90.90.90.90.90.9-0.90.9-0.80.80.80.60.8-0.80.8-0.8-0.6-0.50.7-0.70.70.7-0.7
Rest time, locomotor task time 22.93.74.4-2.0-1.9-2.0-2.1-2.12.0-2.02.1-2.1-2.1-1.7-2.02.1-2.02.01.70.9-2.01.9-1.9-1.71.5
Distance moved, locomotor task time 20.50.61.20.81.10.90.90.9-0.90.9-0.80.80.80.30.9-0.90.6-1.0-0.3-0.20.6-0.50.80.6-0.5
Vertical activity count, locomotor time 20.10.21.4-0.10.1-0.1-0.00.00.1-0.10.0-0.0-0.0-0.80.10.0-0.3-0.20.91.2-0.30.30.3-0.20.4
Light reinforcement 10.00.10.3-0.1-0.1-0.0-0.1-0.20.1-0.10.2-0.3-0.3-0.6-0.20.2-0.30.20.50.0-0.40.4-0.1-0.20.2
Light reinforcement 20.30.57.1-0.1-0.0-0.1-0.2-0.40.3-0.30.3-0.4-0.30.8-0.60.3-0.00.6-0.6-2.7-0.20.2-1.0-0.0-0.4
Bone: marrow area1.02.14.7-1.5-2.2-1.5-1.6-1.81.5-1.51.5-1.6-1.60.4-1.81.7-0.92.2-0.4-0.9-0.90.7-1.7-1.31.2
Bone: maximum diameter0.30.52.70.50.40.50.40.3-0.50.5-0.40.50.31.40.2-0.40.7-0.1-1.3-1.60.7-0.7-0.00.9-1.1
Bone: maximum force2.95.19.52.31.72.32.22.0-2.22.2-2.12.22.13.11.9-2.12.5-1.6-3.1-2.22.5-2.61.82.2-2.4
Bone: maximum moment2.95.19.02.31.72.32.22.0-2.22.2-2.22.22.23.01.9-2.12.5-1.6-3.0-2.12.5-2.61.92.2-2.4
Mean time between licks in bursts0.20.52.60.70.00.60.60.6-0.60.6-0.70.40.5-0.10.8-0.40.5-0.60.11.60.6-0.71.60.00.5
Mean num. licks in bursts0.10.11.0-0.3-0.0-0.3-0.2-0.10.1-0.10.2-0.1-0.1-0.7-0.10.1-0.3-0.00.71.0-0.30.40.0-0.10.2
Cd content in liver0.70.82.1-1.1-0.7-1.2-1.0-0.90.9-0.90.9-0.8-0.9-0.4-1.00.8-0.80.90.4-0.3-0.90.9-1.4-0.50.4
Co content in liver1.21.44.3-1.1-0.8-1.1-1.0-0.91.0-1.01.0-0.9-1.0-1.9-0.80.9-1.30.61.82.1-1.31.3-0.5-1.01.1
Cu content in liver0.00.00.3-0.10.0-0.1-0.1-0.00.1-0.10.1-0.1-0.0-0.50.00.1-0.2-0.10.40.6-0.20.2-0.10.1-0.2
Fe content in liver0.00.00.1-0.3-0.2-0.3-0.2-0.10.1-0.10.2-0.1-0.1-0.1-0.10.1-0.10.10.00.1-0.10.1-0.3-0.20.4
K content in liver0.40.40.90.90.30.80.70.5-0.50.5-0.60.60.60.80.6-0.60.7-0.4-0.8-0.40.8-0.80.90.6-0.5
Mg content in liver0.10.10.30.1-0.40.10.0-0.0-0.00.00.00.00.00.20.1-0.00.20.1-0.40.60.3-0.40.50.3-0.1
Mn content in liver3.43.84.72.22.02.12.12.0-2.02.0-2.01.92.02.01.9-1.92.0-1.8-1.8-1.62.0-1.91.72.0-1.9
Na content in liver0.40.50.80.80.50.80.70.6-0.70.7-0.60.70.60.80.6-0.70.8-0.5-0.9-0.80.7-0.70.70.5-0.5
Rb content in liver2.93.34.3-1.7-2.1-1.8-1.9-1.92.0-2.01.9-1.9-2.0-1.9-1.81.9-1.91.81.81.6-1.81.7-1.2-1.81.9
Se content in liver0.20.22.30.40.40.30.30.2-0.30.3-0.20.30.30.80.1-0.30.4-0.1-0.7-1.50.4-0.4-0.10.4-0.5
Sr content in liver4.33.74.72.02.22.02.12.1-2.02.0-2.02.02.01.72.1-2.02.0-2.1-1.5-0.81.9-1.81.82.0-1.7
Zn content in liver2.83.14.51.71.71.61.71.8-1.81.8-1.81.91.81.61.9-1.91.9-1.9-1.7-0.31.9-1.91.62.1-1.8
Bone: minimum diameter0.50.92.3-0.7-1.4-0.8-0.9-1.10.9-0.90.9-1.0-0.90.9-1.21.1-0.31.5-0.7-1.4-0.30.1-1.1-0.60.6
Time in familiar zone, hab. session 10.10.10.30.20.00.20.30.2-0.40.4-0.30.10.30.50.2-0.20.4-0.1-0.5-0.00.4-0.40.3-0.1-0.1
Time in novel zone, hab. session 11.61.62.4-1.2-1.2-1.2-1.2-1.21.3-1.31.3-1.2-1.3-1.5-1.11.3-1.41.11.51.0-1.31.3-0.8-1.31.4
Total zone transitions, hab. session 10.20.20.40.50.50.50.50.6-0.40.4-0.50.60.50.30.6-0.50.5-0.6-0.30.30.5-0.50.50.5-0.5
Total locomotion distance, hab. session 10.10.10.4-0.4-0.4-0.4-0.3-0.30.3-0.30.3-0.0-0.30.4-0.30.10.00.3-0.6-0.50.1-0.1-0.60.2-0.3
Locomotion velocity, hab. session 10.20.20.80.20.30.30.30.3-0.20.2-0.30.50.30.80.3-0.50.5-0.3-0.9-0.60.5-0.5-0.00.8-0.9
Time in familiar zone, hab. session 20.40.51.8-0.4-0.5-0.3-0.3-0.50.3-0.30.3-0.8-0.4-1.2-0.40.7-0.80.51.41.1-0.80.80.1-0.80.7
Time in novel zone, hab. session 20.60.61.70.60.40.60.60.7-0.60.6-0.60.90.61.10.7-0.80.9-0.6-1.3-0.51.0-1.00.50.7-0.6
Total zone transitions, hab. session 21.31.62.41.30.81.21.31.3-1.21.2-1.31.41.31.21.3-1.31.4-1.2-1.40.61.4-1.51.61.3-1.2
Total locomotion distance, hab. session 20.20.20.70.3-0.00.30.30.3-0.20.2-0.30.50.30.60.3-0.50.5-0.2-0.90.40.6-0.70.50.6-0.8
Locomotion velocity, hab. session 20.10.10.80.1-0.20.10.10.1-0.00.0-0.10.40.10.70.1-0.30.4-0.0-0.90.00.5-0.50.20.6-0.7
Novel to familiar place preference ratio2.22.43.21.61.61.61.61.6-1.41.4-1.51.61.51.71.5-1.51.6-1.5-1.7-1.31.6-1.61.11.8-1.6
Novelty place preference1.41.52.21.31.31.31.21.2-1.11.1-1.21.21.21.41.1-1.11.3-1.1-1.3-1.21.2-1.20.81.5-1.3
Time in novel zone, NPP test1.41.52.11.31.21.31.31.2-1.11.1-1.21.21.21.41.2-1.11.3-1.2-1.3-1.11.3-1.30.91.4-1.2
Total zone transitions, NPP test1.01.42.11.11.01.11.11.3-1.11.1-1.21.51.20.91.3-1.41.3-1.3-1.20.71.3-1.31.31.2-1.2
Total locomotion distance, NPP test0.10.10.70.0-0.1-0.00.00.20.0-0.0-0.10.50.10.20.3-0.50.3-0.3-0.60.90.4-0.40.30.4-0.6
Locomotion velocity, NPP test0.10.10.6-0.1-0.0-0.1-0.10.10.1-0.10.00.4-0.00.00.2-0.40.2-0.2-0.40.80.2-0.20.10.3-0.5
Intraocular pressure0.10.20.7-0.30.1-0.3-0.3-0.30.3-0.30.3-0.4-0.3-0.6-0.30.3-0.50.20.8-0.0-0.60.7-0.4-0.2-0.1
Delta distance traveled before/after self-admin0.70.72.7-0.7-0.7-0.9-0.7-0.60.6-0.60.6-0.9-0.6-1.3-0.50.9-0.90.51.41.6-0.80.8-0.2-0.81.1
Delta ambulatory time before/after self-admin1.01.22.9-0.9-0.9-1.0-0.9-0.90.9-0.90.9-1.1-0.9-1.6-0.71.1-1.20.71.71.7-1.11.1-0.4-1.01.3
Parametrial fat weight1.22.95.5-1.7-2.1-1.8-1.9-2.01.7-1.72.0-1.9-2.0-0.0-2.21.9-1.32.40.1-1.1-1.31.2-2.2-1.41.1
Pavlov. Cond. lever latency1.11.32.8-1.1-0.8-1.2-1.1-1.01.1-1.11.1-1.1-1.1-1.5-1.01.1-1.30.81.71.1-1.31.3-0.9-0.81.2
Pavlov. Cond. magazine entry latency1.41.84.41.21.11.31.21.1-1.31.3-1.31.21.31.90.9-1.21.4-0.8-2.0-2.11.4-1.30.61.0-1.6
Pavlov. Cond. change in total contacts0.70.83.40.60.80.70.60.6-0.70.7-0.70.70.71.30.4-0.70.8-0.4-1.4-1.80.7-0.7-0.20.8-1.5
Pavlov. Cond. index score0.91.12.41.01.01.11.00.9-1.11.1-1.11.01.11.40.8-1.01.1-0.8-1.4-1.61.0-1.00.50.8-1.3
Pavlov. Cond. latency score0.70.91.90.90.81.00.90.8-1.01.0-0.90.90.91.30.7-0.91.0-0.6-1.4-1.31.0-1.00.60.6-1.1
Pavlov. Cond. lever contacts0.60.71.80.80.40.80.70.7-0.80.8-0.80.80.81.20.6-0.70.9-0.5-1.3-0.90.9-1.00.60.5-0.8
Pavlov. Cond. magazine entry number1.01.32.8-1.0-1.3-1.1-1.1-1.11.2-1.21.2-1.1-1.2-1.3-0.91.1-1.11.01.31.7-1.00.9-0.4-0.91.5
Pavlov. Cond. intertrial magazine entries0.10.20.90.20.80.10.20.3-0.10.1-0.20.40.2-0.00.2-0.40.1-0.40.0-0.8-0.00.1-0.30.6-0.9
Pavlov. Cond. lever-magazine prob. diff.1.01.33.01.01.11.11.11.0-1.11.1-1.11.01.11.50.8-1.01.2-0.8-1.5-1.71.1-1.00.40.9-1.4
Pavlov. Cond. response bias1.21.53.11.11.21.31.21.1-1.21.2-1.21.21.21.50.9-1.11.3-0.9-1.6-1.81.2-1.10.61.0-1.6
Pavlov. Cond. lever latency0.60.91.5-1.0-0.8-1.0-1.0-0.81.1-1.11.0-0.8-1.0-1.2-0.70.8-1.00.61.10.8-0.90.9-0.7-0.90.9
Pavlov. Cond. magazine entry latency5.56.77.82.72.82.72.72.7-2.72.7-2.82.82.82.42.6-2.82.6-2.6-2.4-1.72.5-2.42.22.4-2.7
Pavlov. Cond. change in total contacts1.62.53.71.61.71.61.61.5-1.81.8-1.71.51.71.91.3-1.51.6-1.2-1.8-1.91.5-1.40.91.5-1.8
Pavlov. Cond. index score3.14.25.42.12.12.12.12.0-2.22.2-2.22.12.22.31.8-2.02.1-1.8-2.2-2.02.0-1.91.51.8-2.2
Pavlov. Cond. latency score2.93.95.32.02.02.02.01.9-2.12.1-2.02.02.02.31.7-2.02.1-1.6-2.2-2.11.9-1.91.31.8-2.2
Pavlov. Cond. lever contacts0.50.81.20.90.80.90.90.8-1.01.0-1.00.80.91.10.7-0.70.9-0.6-0.9-0.90.8-0.80.60.8-0.9
Pavlov. Cond. magazine entry number8.310.212.0-3.3-3.5-3.3-3.4-3.33.4-3.43.4-3.4-3.4-3.1-3.23.4-3.33.23.02.2-3.13.0-2.6-3.03.2
Pavlov. Cond. intertrial magazine entries1.52.22.9-1.6-1.3-1.6-1.6-1.51.5-1.51.7-1.5-1.6-1.4-1.61.5-1.61.41.40.3-1.61.6-1.7-1.11.1
Pavlov. Cond. lever-magazine prob. diff.3.64.85.82.32.32.22.32.2-2.42.4-2.32.22.32.42.0-2.22.3-1.9-2.3-2.02.1-2.01.62.0-2.3
Pavlov. Cond. response bias2.33.13.91.91.71.91.91.7-2.02.0-1.91.71.91.91.6-1.71.8-1.5-1.7-1.21.7-1.71.51.5-1.7
Time in closed arm before self-admin0.10.11.7-0.0-0.00.1-0.1-0.20.1-0.10.1-0.3-0.10.5-0.40.3-0.00.4-0.3-1.3-0.10.1-0.5-0.1-0.1
Time in closed arm after self-admin0.91.01.6-0.9-1.2-0.8-1.0-1.01.0-1.01.0-1.2-1.0-0.9-0.91.1-1.01.01.00.9-0.90.9-0.6-1.21.2
Time in open arm before self-admin1.71.910.4-1.2-1.5-1.2-1.1-1.01.1-1.11.1-1.1-1.1-1.9-0.71.1-1.20.71.73.2-1.00.9-0.1-1.21.8
Time in open arm after self-admin0.40.50.90.60.70.40.60.8-0.70.7-0.70.90.70.20.9-0.90.6-0.9-0.30.50.6-0.60.80.8-0.5
Bone: periosteal estimation0.20.43.00.1-0.40.1-0.0-0.2-0.00.00.0-0.0-0.01.4-0.30.10.50.6-1.4-1.70.4-0.6-0.40.3-0.4
Bone: periosteal perimeter0.20.32.80.2-0.10.10.0-0.1-0.10.10.00.0-0.01.1-0.30.10.40.4-1.1-1.70.3-0.3-0.40.3-0.5
Bone: post-yield work0.50.74.2-0.2-0.6-0.2-0.2-0.3-0.00.00.1-0.2-0.11.9-0.50.20.50.9-1.9-2.10.5-0.6-0.80.5-1.1
Progressive ratio test 1 active lever presses0.30.40.7-0.9-0.7-0.9-0.8-0.70.8-0.80.7-0.5-0.7-0.0-0.70.6-0.40.7-0.1-0.5-0.40.4-0.8-0.50.3
Progressive ratio test 1 breakpoint0.30.40.7-0.8-0.7-0.8-0.8-0.70.8-0.80.7-0.5-0.70.0-0.70.6-0.40.7-0.1-0.6-0.40.4-0.9-0.50.2
Progressive ratio test 1 inactive lever presses0.60.81.90.80.70.80.80.8-0.70.7-0.90.90.81.30.8-0.91.0-0.7-1.4-1.11.1-1.10.70.8-0.9
Progressive ratio test 2 active lever presses0.70.91.9-1.1-0.9-1.1-1.0-1.01.0-1.01.0-0.8-0.90.4-1.20.9-0.51.2-0.3-1.3-0.50.6-1.4-0.60.1
Progressive ratio test 2 breakpoint0.70.81.7-1.0-0.9-1.1-1.0-1.00.9-0.90.9-0.7-0.90.4-1.20.8-0.51.2-0.4-1.3-0.50.5-1.3-0.60.1
Progressive ratio test 2 inactive lever presses0.40.62.3-0.8-0.7-0.8-0.8-0.80.8-0.80.7-0.6-0.70.7-1.00.7-0.31.1-0.7-1.5-0.30.4-1.2-0.4-0.1
Incentive Sensitization - Responses0.71.03.30.80.60.80.80.7-0.90.9-0.80.80.81.80.6-0.81.2-0.5-1.7-1.71.1-1.10.40.9-1.2
Incentive Sensitization - Breakpoint0.60.83.00.60.50.60.60.6-0.80.8-0.70.70.71.70.4-0.71.0-0.3-1.6-1.71.0-1.00.30.8-1.1
Sum of active levers in priming session hrs 5-61.61.56.11.01.91.01.11.1-1.11.1-1.11.21.11.00.8-1.10.9-1.1-0.8-2.50.6-0.40.11.5-1.9
Progressive ratio0.10.10.90.1-0.30.10.0-0.2-0.00.0-0.1-0.1-0.00.9-0.20.10.30.4-0.8-0.90.3-0.3-0.20.0-0.1
Food seeking constrained by brief footshock0.10.10.3-0.2-0.4-0.2-0.2-0.20.3-0.30.2-0.2-0.2-0.3-0.20.3-0.20.20.20.6-0.10.1-0.0-0.30.5
Seeking ratio, punishment vs. effort0.20.32.9-0.3-0.3-0.3-0.2-0.10.2-0.20.2-0.1-0.1-0.90.10.1-0.3-0.20.71.7-0.20.20.4-0.30.6
Retroperitoneal fat weight3.414.620.7-4.0-4.6-3.9-4.2-4.34.2-4.24.2-4.2-4.3-2.6-4.34.1-3.74.42.41.1-3.53.4-3.7-3.73.5
Reaction time number correct0.30.51.71.10.61.00.90.8-0.90.9-0.90.60.70.30.8-0.60.6-0.7-0.20.40.6-0.61.30.1-0.1
Reaction time mean minus median0.40.93.80.81.60.80.90.9-0.90.9-0.90.70.91.00.6-0.70.7-0.8-0.7-2.00.5-0.3-0.21.2-1.4
Reaction time mean minus median AUC0.10.31.30.41.10.40.50.5-0.50.5-0.50.30.50.10.3-0.40.2-0.60.1-0.90.00.2-0.10.7-0.7
Reaction time num false alarms0.60.85.9-0.8-0.7-0.9-0.7-0.50.5-0.50.6-0.4-0.6-1.5-0.30.4-0.80.21.32.4-0.70.60.0-1.01.3
Reaction time num false alarms AUC0.30.55.9-0.3-0.2-0.3-0.20.1-0.10.10.10.1-0.1-1.20.3-0.1-0.3-0.41.12.4-0.20.20.6-0.51.0
Reaction time trials correct on left0.30.51.71.10.61.00.90.8-0.90.9-0.90.60.70.30.8-0.60.6-0.7-0.20.40.6-0.61.30.1-0.1
Reaction time trials on left0.30.61.81.10.61.00.90.8-0.90.9-0.90.60.80.20.9-0.60.6-0.8-0.20.50.6-0.71.30.1-0.1
Reaction time mean0.10.11.2-0.30.5-0.3-0.10.0-0.10.1-0.10.00.10.2-0.2-0.0-0.10.0-0.0-1.1-0.20.4-0.90.3-0.5
Reaction time mean AUC0.10.21.1-0.30.3-0.3-0.2-0.20.1-0.10.1-0.2-0.10.0-0.40.2-0.30.20.1-1.1-0.40.6-0.90.1-0.3
Median of all reaction times0.10.10.6-0.30.3-0.3-0.10.0-0.10.1-0.00.10.10.2-0.2-0.1-0.00.1-0.1-0.8-0.10.2-0.70.2-0.4
Reaction time omissions0.30.41.40.61.20.50.70.8-0.80.8-0.80.70.80.20.7-0.70.5-0.9-0.1-0.30.4-0.20.30.8-0.7
Reaction time false alarm rate0.40.53.3-0.9-0.6-0.9-0.7-0.40.5-0.50.6-0.3-0.5-1.1-0.30.3-0.60.21.01.8-0.50.5-0.3-0.61.0
Reaction time premature initiation rate3.85.310.02.61.62.62.42.4-2.52.5-2.32.22.51.92.5-2.32.5-2.3-2.00.22.6-2.73.21.8-1.4
Reaction time premature initiations3.76.613.63.12.13.02.92.7-2.92.9-2.72.52.71.72.9-2.62.6-2.7-1.80.52.7-2.83.71.8-1.4
Std. dev. reaction times0.10.21.0-0.30.8-0.3-0.10.0-0.10.1-0.0-0.10.0-0.2-0.20.1-0.3-0.10.4-1.0-0.40.6-0.90.3-0.5
Reaction time trials completed0.30.61.81.10.61.00.90.8-0.90.9-0.90.60.80.20.9-0.60.6-0.8-0.20.50.6-0.71.30.1-0.1
Reaction time trials AUC0.20.41.61.00.40.90.80.7-0.80.8-0.80.50.70.20.8-0.50.5-0.6-0.10.50.6-0.61.3-0.00.0
Run reversals in cocaine runway, females0.40.41.70.5-0.30.50.50.4-0.50.5-0.50.60.50.60.6-0.50.7-0.4-0.81.30.9-1.11.00.20.2
Run reversals in cocaine runway, males0.50.50.9-0.7-0.5-0.7-0.7-0.70.8-0.80.7-0.7-0.7-1.0-0.60.7-0.80.60.90.5-0.80.8-0.6-0.60.8
Latency to leave start box in cocaine runway0.30.41.0-0.6-1.0-0.7-0.7-0.80.6-0.60.7-0.7-0.70.1-0.80.7-0.40.9-0.0-0.1-0.40.3-0.6-0.50.4
Latency to leave start box in cocaine runway, F0.00.10.20.2-0.00.20.20.1-0.20.2-0.10.20.10.50.1-0.10.3-0.0-0.4-0.30.3-0.30.30.2-0.3
Latency to leave start box in cocaine runway, M2.12.02.9-1.5-1.7-1.5-1.6-1.61.5-1.51.5-1.5-1.5-0.8-1.61.6-1.31.70.80.3-1.31.2-1.4-1.31.1
Std. dev. time between licks in bursts0.20.32.3-0.2-0.7-0.2-0.2-0.30.3-0.30.2-0.5-0.3-0.7-0.10.5-0.40.30.81.5-0.30.20.6-0.60.9
Total sessions with >9 infusions0.70.91.5-1.1-1.2-1.1-1.1-1.11.0-1.01.1-0.9-1.0-0.5-1.11.0-0.81.10.30.1-0.70.7-0.9-1.00.8
Short access day 1 total inactive lever presses0.10.10.4-0.4-0.6-0.4-0.2-0.20.1-0.10.0-0.2-0.10.5-0.20.10.10.3-0.60.20.2-0.2-0.2-0.30.3
Short access day 10 total inactive lever presses0.30.71.0-0.9-0.8-0.9-0.8-0.80.8-0.80.8-0.8-0.9-1.0-0.80.7-0.90.70.91.0-0.90.9-0.7-0.80.8
Short access day 1 total infusions1.11.52.8-1.4-1.7-1.3-1.4-1.41.3-1.31.3-1.2-1.3-0.6-1.41.3-1.11.50.40.4-0.90.9-1.1-1.41.2
Short access day 10 total infusions0.30.41.4-0.6-1.2-0.6-0.6-0.70.6-0.60.6-0.5-0.60.7-0.70.5-0.00.9-0.9-0.50.1-0.2-0.5-0.50.4
Short access total infusions0.60.82.4-1.0-1.6-0.9-1.0-1.01.0-1.00.9-0.8-0.90.0-1.00.9-0.51.2-0.30.4-0.30.2-0.6-1.01.0
Short access day 1 locomotion0.20.30.6-0.6-0.8-0.6-0.6-0.60.6-0.60.5-0.5-0.60.2-0.60.5-0.30.7-0.2-0.4-0.20.2-0.6-0.50.3
Short access day 10 total locomotion0.10.31.80.0-0.30.00.00.0-0.10.1-0.10.2-0.01.2-0.1-0.20.60.2-1.3-1.00.6-0.7-0.10.3-0.5
Short access total locomotion0.20.20.7-0.5-0.7-0.5-0.4-0.40.4-0.40.4-0.2-0.40.7-0.50.20.10.6-0.8-0.60.2-0.2-0.5-0.2-0.1
One hour access (0.3 mA shock)0.91.02.0-1.2-1.3-1.2-1.2-1.21.1-1.11.2-1.0-1.20.2-1.30.9-0.71.4-0.2-0.6-0.60.6-1.3-0.80.4
Compulsive drug intake0.70.81.81.00.91.11.01.0-1.11.1-0.90.80.9-0.41.2-0.70.5-1.20.31.20.5-0.51.30.5-0.1
One hour access (shock baseline)2.23.45.8-2.1-2.0-2.1-2.1-2.12.2-2.22.1-1.8-2.1-0.3-2.31.8-1.52.40.3-1.2-1.51.5-2.4-1.40.8
Social response proportion0.00.10.40.50.10.50.30.1-0.10.1-0.10.00.20.00.2-0.20.1-0.1-0.00.30.1-0.10.6-0.00.0
Social responses0.10.11.00.40.40.40.30.2-0.20.2-0.10.10.2-0.60.3-0.1-0.1-0.40.71.0-0.10.20.60.10.2
Social time0.10.21.40.00.10.1-0.1-0.00.1-0.10.2-0.2-0.1-0.70.10.2-0.4-0.20.91.2-0.30.40.30.00.3
Soleus weight3.08.910.2-3.1-3.1-3.1-3.1-3.13.2-3.23.1-3.0-3.2-2.7-3.13.0-3.13.02.61.3-3.02.9-2.8-3.23.2
Bone: stiffness0.91.54.01.21.11.21.11.0-1.01.0-1.11.11.01.70.8-1.01.2-0.7-1.6-2.01.1-1.10.61.3-1.7
Tibialis anterior weight9.030.434.55.95.75.95.85.9-5.85.8-5.85.85.74.85.8-5.85.7-5.8-4.6-2.25.6-5.55.25.8-5.1
Time to tail flick, vehicle, before self-admin0.30.31.30.30.10.30.30.3-0.40.4-0.30.40.41.10.2-0.40.6-0.1-1.1-0.80.7-0.70.10.5-0.6
Time to tail flick, vehicle, after self-admin0.20.30.70.40.10.50.40.5-0.50.5-0.50.50.60.70.5-0.50.7-0.4-0.70.20.8-0.80.60.3-0.1
Time to tail flick, test, before self-admin0.30.41.20.4-0.40.30.40.3-0.50.5-0.50.30.41.00.5-0.30.8-0.2-1.10.60.9-1.10.70.5-0.1
Time to tail flick, test, after self-admin0.10.10.50.20.30.30.20.2-0.20.2-0.20.10.20.40.1-0.20.2-0.1-0.3-0.70.1-0.1-0.10.3-0.4
Delta time to tail flick, vehicle, before/after SA0.20.20.40.40.30.40.40.4-0.30.3-0.40.50.40.10.5-0.40.4-0.5-0.20.60.4-0.50.70.2-0.0
Delta time to tail flick, test, before/after SA0.20.21.20.11.00.20.20.2-0.10.1-0.10.20.1-0.40.0-0.2-0.3-0.30.5-1.1-0.50.6-0.40.2-0.5
Tibia length1.84.99.62.22.42.12.12.0-2.02.0-2.02.22.02.61.8-2.32.2-1.8-2.6-2.82.1-2.01.02.8-3.1
Ambulatory time before self-admin1.82.74.71.61.81.61.61.6-1.61.6-1.61.71.72.01.4-1.61.7-1.4-1.9-2.21.6-1.50.91.6-1.8
Ambulatory time after self-admin0.20.20.80.40.60.40.50.5-0.50.5-0.60.30.60.70.4-0.30.5-0.3-0.4-0.90.4-0.40.10.5-0.5
Bone: tissue strength0.40.40.8-0.3-0.7-0.3-0.5-0.70.6-0.60.6-0.7-0.6-0.7-0.60.8-0.70.70.80.6-0.70.6-0.0-0.90.8
Total heroin consumption5.76.710.02.73.22.72.82.9-2.72.7-2.72.92.71.82.8-2.82.5-3.0-1.8-1.02.3-2.22.42.9-2.7
Bone: trabecular number1.11.93.61.30.91.31.31.2-1.41.4-1.41.21.41.91.2-1.21.6-1.0-1.9-1.11.6-1.71.11.2-1.2
Bone: trabecular spacing0.71.02.7-0.8-0.7-0.7-0.8-0.80.9-0.90.9-0.8-0.9-1.6-0.70.8-1.10.61.51.4-1.11.2-0.3-1.00.8
Bone: trabecular thickness0.10.21.0-0.4-0.2-0.4-0.3-0.40.3-0.30.2-0.4-0.20.3-0.50.4-0.20.5-0.0-1.0-0.30.3-0.8-0.40.2
Bone: trabecular tissue density5.17.59.5-3.0-2.3-3.0-2.9-2.72.9-2.92.9-2.6-2.9-2.9-2.82.6-3.02.52.81.2-3.03.1-2.8-2.42.3
Water consumed over 24 hours0.50.61.61.10.81.11.00.9-0.90.9-0.90.60.90.30.9-0.60.7-0.9-0.00.40.7-0.61.30.5-0.2
Number of responses in last shaping day0.10.10.40.30.20.40.30.4-0.30.3-0.30.40.3-0.00.5-0.40.3-0.5-0.20.50.4-0.40.60.10.1