Ganab

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA isoform ratio NM_001398785.1 0.05 0.04 1.6e-05 0.06 0.05 0.05 0.05 1.8e-05 8.7e-05 1.1e-04 4.0e-05
2 NAcc gene expression Ganab 0.03 0.02 7.3e-05 0.02 0.03 0.02 0.02 1.3e-04 5.3e-05 2.1e-04 2.7e-04
3 PL gene expression Ganab 0.04 0.02 2.5e-06 0.06 0.06 0.04 0.06 3.6e-07 1.0e-06 2.2e-05 7.0e-07
4 BLA gene expression Ganab 0.12 0.07 2.1e-06 0.09 0.09 0.1 0.09 1.3e-05 1.3e-05 5.3e-06 1.3e-05
5 IC intron excision ratio chr1_215223064_215226988 0.19 0.1 5.3e-08 0.14 0.16 0.09 0.16 1.5e-06 2.2e-07 1.1e-04 2.5e-07
6 Brain isoform ratio NM_001398784.1 0.06 0.04 5.9e-07 0.08 0.06 0.06 0.07 1.3e-07 4.8e-06 1.8e-06 7.6e-07
7 Brain isoform ratio NM_001398785.1 0.06 0.04 6.4e-07 0.08 0.06 0.06 0.07 6.0e-08 4.0e-06 1.4e-06 2.0e-07
8 Liver gene expression Ganab 0.28 0.17 2.1e-09 0.07 0.06 0.06 0.07 6.0e-08 9.2e-08 1.1e-07 6.0e-08
9 NAcc intron excision ratio chr1_215223584_215226988 0.09 0.05 0.0e+00 0.14 0.14 0.14 0.14 8.4e-21 1.6e-20 1.6e-20 3.4e-20
10 PL intron excision ratio chr1_215223064_215226988 0.15 0.09 0.0e+00 0.2 0.18 0.19 0.19 3.6e-21 3.7e-19 2.3e-20 9.9e-21
11 NAcc intron excision ratio chr1_215223064_215226988 0.09 0.05 0.0e+00 0.15 0.14 0.14 0.14 1.8e-21 4.5e-21 3.9e-21 4.9e-21
12 IC gene expression Ganab 0.11 0.07 2.6e-04 0.02 0.02 0.04 0.02 6.2e-02 5.7e-02 7.7e-03 3.9e-02
13 Brain gene expression Ganab 0.09 0.05 1.9e-10 0.1 0.11 0.1 0.1 2.2e-09 3.1e-10 2.2e-09 9.6e-10
14 NAcc isoform ratio NM_001398785.1 0.01 0.01 5.3e-03 0.01 0.01 0.01 0.01 1.8e-02 4.5e-03 8.1e-03 1.0e-02
15 IC intron excision ratio chr1_215223584_215226988 0.23 0.11 5.5e-09 0.16 0.18 0.17 0.18 2.1e-07 3.6e-08 8.3e-08 5.8e-08
16 NAcc isoform ratio NM_001398784.1 0.02 0.02 2.5e-04 0.02 0.03 0.03 0.03 1.2e-03 7.0e-05 5.4e-05 7.8e-05
17 Adipose isoform ratio NM_001398784.1 0.03 0.02 9.6e-03 -0 0 0 -0 3.9e-01 1.5e-01 8.0e-02 5.5e-01
18 pVTA gene expression Ganab 0.15 0.08 1.8e-15 0.17 0.19 0.18 0.18 4.9e-14 5.1e-15 7.8e-15 1.3e-14
19 pVTA isoform ratio NM_001398784.1 0.05 0.04 9.8e-05 0.03 0.03 0.03 0.03 3.2e-03 1.6e-03 3.2e-03 2.0e-03
20 pVTA intron excision ratio chr1_215233340_215234658 0.03 0.02 4.4e-03 0.01 0.01 0 0.01 6.2e-02 7.9e-02 1.2e-01 1.1e-01
21 Brain intron excision ratio chr1_215233340_215234658 0.09 0.06 7.3e-08 0.06 0.06 0.07 0.08 1.8e-06 1.3e-06 4.2e-07 1.1e-07
22 Brain intron excision ratio chr1_215233879_215234658 0.05 0.03 1.0e-04 0.01 0.03 0.03 0.03 1.8e-02 1.2e-03 3.6e-04 4.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.40.71.8-0.70.4-0.6-0.70.70.8-0.8-0.70.8-0.7-0.8-1.30.71.0-0.51.30.91.0-1.1-0.50.60.7
Area under the delay curve0.00.10.4-0.1-0.3-0.1-0.10.10.1-0.1-0.10.1-0.1-0.1-0.30.20.3-0.10.4-0.60.4-0.4-0.40.1-0.1
BMI with tail2.38.116.7-2.81.5-2.7-2.72.52.8-2.8-2.82.7-2.7-2.6-3.92.63.4-2.14.11.33.6-3.8-2.72.62.1
BMI without tail0.21.32.9-1.30.3-1.2-1.11.01.0-1.0-1.21.0-1.0-0.9-1.21.21.4-1.01.4-0.41.5-1.7-1.61.00.5
Body weight3.113.719.5-4.02.8-4.0-3.83.63.8-3.8-3.93.7-3.7-3.6-4.13.74.2-3.44.21.44.3-4.4-3.93.42.8
Weight adjusted by age0.41.11.7-1.11.0-1.1-1.11.01.1-1.1-1.01.1-1.0-1.1-1.31.01.1-0.91.11.11.1-1.1-0.90.81.1
Bone surface2.34.67.7-2.11.8-2.1-2.12.02.2-2.2-2.02.2-2.1-2.1-2.81.92.4-1.72.62.02.3-2.3-1.62.02.2
Bone volume1.02.14.7-1.31.1-1.3-1.31.21.4-1.4-1.31.4-1.3-1.4-2.21.11.6-0.92.01.91.6-1.6-0.81.31.5
Breakpoint value in progressive ratio session1.52.74.5-1.72.1-1.7-1.81.81.7-1.7-1.71.7-1.7-1.7-1.21.71.5-1.91.11.41.4-1.3-1.31.81.8
Number of licking bursts0.00.00.1-0.2-0.1-0.2-0.1-0.0-0.00.0-0.00.10.10.0-0.10.00.00.0-0.00.20.0-0.1-0.2-0.0-0.2
Context. condit. distance diff. score0.40.41.10.9-1.10.90.8-0.7-0.70.70.7-0.70.50.70.3-0.6-0.40.6-0.1-1.0-0.30.20.5-0.5-0.7
Locomotion velocity, session 10.10.11.90.3-0.40.30.2-0.1-0.10.10.1-0.1-0.10.10.30.1-0.0-0.0-0.0-1.40.1-0.2-0.4-0.2-0.4
Locomotion distance, session 10.50.61.2-0.50.2-0.4-0.50.70.6-0.6-0.80.6-1.0-0.6-0.70.80.9-0.71.1-0.91.0-1.1-1.00.90.6
Locomotion velocity, session 22.42.94.0-1.81.6-1.7-1.71.71.6-1.6-1.91.7-2.0-1.6-1.61.81.9-1.81.90.41.9-1.9-1.71.81.7
Locomotion distance, session 20.10.20.7-0.40.2-0.3-0.40.50.3-0.3-0.50.3-0.6-0.3-0.10.60.4-0.60.3-0.80.5-0.6-0.70.50.2
Locomotion velocity, session 30.30.41.5-0.5-0.2-0.4-0.40.40.3-0.3-0.50.4-0.5-0.4-1.00.50.8-0.21.2-0.10.9-1.1-0.80.40.2
Locomotion distance, session 30.10.10.6-0.3-0.1-0.3-0.20.20.2-0.2-0.20.2-0.1-0.1-0.00.30.2-0.10.1-0.80.2-0.3-0.6-0.1-0.1
Stereotopy head waving bouts, day 30.20.20.80.6-0.90.60.6-0.5-0.50.50.3-0.60.20.5-0.4-0.4-0.00.50.6-0.20.1-0.30.5-0.1-0.3
Stereotopy head waving duration, day 30.10.20.50.6-0.70.60.5-0.4-0.50.50.3-0.50.10.5-0.1-0.3-0.10.30.3-0.60.1-0.10.40.1-0.3
Locomotion velocity, session 70.00.00.30.1-0.20.20.2-0.1-0.20.2-0.0-0.2-0.10.2-0.4-0.10.20.10.50.00.2-0.30.20.10.0
Locomotion distance, session 70.10.10.80.4-0.70.30.4-0.3-0.40.40.2-0.40.20.40.0-0.2-0.10.30.2-0.90.0-0.2-0.1-0.3-0.4
Stereotopy head waving bouts, day 70.30.31.1-0.40.5-0.4-0.40.40.4-0.4-0.50.4-0.5-0.4-0.80.30.6-0.30.81.10.5-0.50.00.80.6
Stereotopy head waving duration, day 71.61.92.6-1.41.4-1.4-1.41.41.4-1.4-1.41.4-1.4-1.4-1.51.31.5-1.31.41.21.5-1.4-1.11.61.3
Locomotion velocity, session 80.20.22.50.4-0.40.40.4-0.2-0.30.30.1-0.40.00.30.8-0.0-0.3-0.1-0.5-1.6-0.20.2-0.2-0.3-0.5
Locomotion distance, session 80.30.41.20.8-1.10.90.8-0.7-0.80.80.6-0.80.50.8-0.0-0.6-0.30.70.3-0.6-0.20.10.6-0.3-0.4
Degree of sensitization distance0.10.10.70.3-0.60.20.3-0.2-0.20.20.2-0.20.10.2-0.7-0.20.20.30.80.30.3-0.40.20.0-0.1
Degree of sensitization stereotypy1.11.32.6-1.01.2-1.1-1.11.01.0-1.0-1.11.1-1.1-1.1-1.30.91.1-0.91.31.61.0-1.0-0.51.41.2
Conditioned locomotion0.50.60.7-0.80.7-0.8-0.80.80.9-0.9-0.80.8-0.8-0.8-0.60.90.8-0.80.5-0.00.8-0.8-0.80.60.2
Cocaine response after cond. corrected0.60.94.01.2-1.21.21.1-0.8-0.70.70.9-0.90.70.91.0-0.7-0.80.7-0.7-2.0-0.70.60.4-0.7-0.9
Cocaine response after cond. not corrected0.30.51.60.9-1.00.90.8-0.7-0.60.60.7-0.70.50.70.7-0.6-0.60.7-0.4-1.3-0.50.50.4-0.5-0.5
Cocaine response before conditioning0.50.73.4-0.91.0-0.9-0.80.60.7-0.7-0.80.7-0.7-0.8-0.70.50.6-0.50.81.80.5-0.4-0.30.61.2
Saline control response2.53.55.8-2.21.7-2.2-2.02.01.9-1.9-2.11.9-2.0-1.8-1.22.11.9-2.01.3-0.51.9-1.9-2.41.91.4
Bone: connectivity density1.93.04.7-1.71.3-1.6-1.71.71.8-1.8-1.71.8-1.7-1.8-2.11.62.0-1.52.21.12.0-2.0-1.51.51.6
Bone: cortical apparent density0.20.30.8-0.40.9-0.4-0.50.70.7-0.7-0.60.6-0.7-0.60.00.70.4-0.8-0.0-0.20.3-0.2-0.30.80.8
Bone: cortical area1.01.62.2-1.41.2-1.4-1.31.11.2-1.2-1.31.2-1.3-1.2-1.51.01.3-1.01.41.31.2-1.2-1.01.31.5
Bone: cortical porosity0.10.10.40.20.40.20.10.0-0.10.10.1-0.10.00.10.5-0.0-0.3-0.2-0.6-0.2-0.40.40.40.20.1
Bone: cortical porosity0.10.10.2-0.00.5-0.0-0.10.20.1-0.1-0.10.1-0.2-0.10.40.2-0.1-0.4-0.4-0.4-0.10.20.00.40.2
Bone: cortical thickness2.84.76.8-2.52.5-2.5-2.52.52.3-2.3-2.42.3-2.4-2.3-1.02.52.0-2.61.0-0.11.9-1.8-2.62.01.9
Bone: cortical thickness0.30.41.0-0.60.6-0.6-0.70.70.7-0.7-0.60.7-0.7-0.70.20.80.4-0.8-0.1-1.00.5-0.4-0.90.40.3
Bone: cortical tissue density0.30.51.2-0.61.1-0.6-0.70.90.8-0.8-0.80.7-0.9-0.8-0.10.80.5-1.00.1-0.20.5-0.3-0.51.00.9
Condit. Reinf. active minus inactive responses1.11.21.5-1.11.1-1.0-1.21.21.2-1.2-1.11.2-1.2-1.2-1.11.11.2-1.11.10.71.1-1.1-1.00.91.0
Condit. Reinf. active-inactive response ratio0.40.40.7-0.60.8-0.5-0.70.80.8-0.8-0.60.8-0.7-0.8-0.40.80.6-0.80.3-0.10.6-0.6-0.60.60.5
Condit. Reinf. active responses1.11.42.5-1.11.1-1.0-1.11.11.1-1.1-1.11.2-1.2-1.2-1.61.01.3-0.91.61.61.2-1.2-0.60.91.3
Condit. Reinf. inactive responses0.20.32.9-0.1-0.1-0.1-0.0-0.1-0.10.1-0.00.0-0.0-0.0-1.0-0.20.30.31.01.70.2-0.30.4-0.10.4
Incentive salience index mean1.31.72.6-1.31.0-1.3-1.31.31.3-1.3-1.31.3-1.4-1.3-1.51.21.5-1.11.60.91.4-1.5-1.21.01.3
Condit. Reinf. lever presses1.01.43.2-1.20.8-1.3-1.21.01.1-1.1-1.21.1-1.2-1.1-1.61.01.4-0.81.81.01.4-1.4-1.01.01.3
Condit. Reinf. active minus inactive responses0.10.10.70.20.10.30.3-0.3-0.30.30.3-0.40.30.30.1-0.5-0.30.4-0.00.8-0.40.50.70.20.6
Condit. Reinf. active-inactive response ratio0.40.63.00.7-0.40.70.7-0.7-0.70.70.6-0.70.60.7-0.3-0.9-0.40.90.41.7-0.50.51.40.10.5
Condit. Reinf. active responses0.10.10.5-0.40.5-0.4-0.30.30.3-0.3-0.40.2-0.3-0.3-0.20.20.3-0.30.20.30.2-0.2-0.20.60.7
Condit. Reinf. inactive responses0.20.31.5-0.60.3-0.6-0.50.50.6-0.6-0.50.4-0.4-0.50.40.60.3-0.6-0.4-1.20.3-0.3-1.1-0.0-0.3
Condit. Reinf. lever presses1.01.52.1-1.41.1-1.4-1.31.11.3-1.3-1.21.3-1.1-1.2-1.51.01.3-0.91.31.21.2-1.2-1.01.11.3
Condit. Reinf. lever reinforcers received0.20.30.8-0.70.8-0.6-0.60.60.6-0.6-0.60.5-0.6-0.5-0.30.50.5-0.50.40.40.4-0.3-0.40.80.9
Conditioned reinforcement - actives0.10.43.60.60.10.60.4-0.4-0.60.60.5-0.30.40.4-0.3-0.6-0.30.60.11.9-0.40.51.0-0.10.4
Conditioned reinforcement - inactives0.10.33.10.3-0.10.30.1-0.2-0.20.20.2-0.00.10.1-1.1-0.40.20.50.91.80.1-0.10.70.10.6
Conditioned locomotion1.62.43.81.9-1.91.91.8-1.8-1.71.71.7-1.61.61.70.6-1.8-1.31.9-0.5-0.2-1.31.21.8-1.5-1.2
Patch foraging indifference point 0 sec0.30.81.3-0.90.8-0.9-0.90.90.9-0.9-0.90.8-0.9-0.9-0.80.91.0-0.90.8-0.41.0-1.0-1.01.11.0
Patch foraging indifference point AUC0.92.14.2-1.42.0-1.4-1.51.51.5-1.5-1.51.4-1.5-1.5-1.41.31.4-1.41.22.01.2-1.1-0.61.51.6
Delay disc. indifference point, 0s delay0.40.41.40.7-1.20.70.7-0.7-0.70.70.6-0.70.70.70.2-0.6-0.40.7-0.1-1.1-0.20.10.2-0.7-0.8
Delay disc. indifference point, 16s delay0.10.20.6-0.30.2-0.4-0.30.30.3-0.3-0.30.3-0.3-0.3-0.70.20.5-0.10.80.50.5-0.5-0.20.30.4
Delay disc. indifference point, 2s delay0.20.20.60.5-0.80.50.5-0.6-0.50.50.5-0.50.50.5-0.1-0.6-0.30.70.20.1-0.20.20.5-0.5-0.4
Delay disc. indifference point, 24s delay0.10.10.5-0.3-0.0-0.2-0.20.30.3-0.3-0.30.3-0.3-0.3-0.10.40.3-0.30.1-0.70.4-0.4-0.60.1-0.1
Delay disc. indifference point, 4s delay0.30.31.4-0.4-0.1-0.4-0.40.40.4-0.4-0.50.4-0.4-0.4-0.40.60.6-0.50.5-1.20.7-0.8-1.00.40.0
Delay disc. indifference point, 8s delay0.30.52.00.7-0.80.70.7-0.6-0.70.70.7-0.70.70.70.8-0.5-0.70.5-0.8-1.4-0.50.50.2-0.6-0.8
Indifference point function ln k1.85.611.92.5-3.12.52.5-2.4-2.22.22.4-2.32.32.32.2-2.1-2.22.3-1.9-3.5-1.91.81.3-2.4-2.6
Indifference point function log k1.85.611.92.5-3.12.52.5-2.4-2.22.22.4-2.32.32.32.2-2.1-2.22.3-1.9-3.5-1.91.81.3-2.4-2.6
Patch foraging total patch changes 0 sec0.30.81.4-0.90.8-0.9-0.90.90.9-0.9-0.90.8-1.0-0.9-0.41.00.9-1.00.5-1.00.9-0.9-1.21.00.8
Patch foraging total patch changes 12 sec6.08.010.6-2.93.3-3.0-2.93.13.0-3.0-3.02.9-3.1-2.9-2.23.02.8-3.12.31.22.7-2.6-2.53.13.0
Patch foraging total patch changes 18 sec0.40.81.6-0.91.3-1.0-0.91.01.0-1.0-1.00.8-1.0-0.9-0.50.90.8-1.00.50.50.7-0.7-0.61.11.2
Patch foraging total patch changes 24 sec2.48.210.0-3.02.7-3.0-3.03.03.2-3.2-2.92.9-3.0-2.9-2.73.03.0-2.92.71.03.0-3.0-2.82.92.5
Patch foraging total patch changes 6 sec1.01.82.3-1.41.2-1.4-1.31.41.5-1.5-1.41.3-1.4-1.3-1.11.41.4-1.41.2-0.21.4-1.5-1.41.41.1
Patch foraging time to switch 0 sec0.20.72.6-0.60.6-0.6-0.60.60.5-0.5-0.80.6-0.8-0.6-1.30.51.0-0.51.41.60.9-0.9-0.20.81.0
Patch foraging water rate 0 sec0.20.92.50.8-0.90.90.8-0.8-0.70.70.9-0.70.90.71.2-0.8-1.00.8-1.3-1.6-1.01.00.4-0.9-1.0
Patch foraging water rate 12 sec0.93.77.41.7-2.21.71.8-1.8-1.71.71.9-1.72.01.82.2-1.6-1.91.7-2.2-2.7-1.81.70.7-2.2-2.4
Patch foraging water rate 18 sec0.51.16.40.7-1.60.70.8-0.9-0.80.80.9-0.71.00.81.1-0.6-0.80.9-0.9-2.5-0.60.5-0.3-1.2-1.5
Patch foraging water rate 24 sec1.42.03.91.5-1.61.41.5-1.4-1.41.41.4-1.41.31.41.6-1.3-1.51.3-1.4-2.0-1.41.40.9-1.5-1.5
Patch foraging water rate 6 sec1.82.77.31.4-1.91.41.5-1.5-1.51.51.6-1.51.61.51.9-1.3-1.71.4-1.9-2.7-1.51.40.6-1.8-2.0
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.20.0-0.3-0.20.20.2-0.2-0.20.2-0.2-0.2-0.30.20.2-0.10.3-0.10.3-0.3-0.30.10.1
Distance traveled before self-admin1.43.14.5-1.71.8-1.8-1.81.71.8-1.8-1.81.8-1.8-1.8-2.11.61.9-1.52.01.91.8-1.7-1.21.81.8
Distance traveled after self-admin0.30.61.2-0.81.1-0.7-0.80.90.9-0.9-0.60.9-0.7-1.0-0.60.80.7-0.80.30.70.6-0.5-0.50.90.8
Extensor digitorum longus weight6.224.629.2-5.44.5-5.4-5.35.15.2-5.2-5.25.3-5.0-5.1-4.75.25.3-4.94.51.75.3-5.3-5.24.84.1
Bone: elastic displacement0.50.72.00.6-0.50.70.6-0.6-0.60.60.7-0.60.70.61.3-0.5-0.90.4-1.4-1.2-0.80.90.2-0.9-1.3
Bone: elastic work0.81.02.4-1.10.8-1.0-1.11.11.1-1.1-1.01.1-1.1-1.1-0.31.30.9-1.20.2-1.01.0-1.0-1.50.5-0.0
Bone: endosteal estimation0.71.74.01.4-2.01.31.5-1.6-1.31.31.5-1.41.41.4-0.5-1.7-0.82.00.61.0-0.70.51.6-1.1-1.0
Bone: endosteal perimeter1.12.86.01.7-2.11.71.8-2.0-1.71.71.8-1.81.81.8-0.5-2.2-1.12.40.51.8-1.10.92.3-1.2-0.9
Epididymis fat weight0.31.74.11.1-1.71.01.3-1.6-1.31.31.4-1.41.61.5-0.3-1.8-0.92.00.21.5-0.90.81.5-1.0-0.5
Delta time in closed arm before/after self-admin0.90.93.3-0.80.3-0.8-0.80.90.8-0.8-0.90.8-1.0-0.9-0.21.20.9-1.10.5-1.81.1-1.2-1.60.60.1
Delta time in open arm before/after self-admin2.12.55.3-1.41.8-1.4-1.51.51.5-1.5-1.61.5-1.7-1.4-1.81.31.6-1.41.82.31.4-1.3-0.71.71.9
Diff in mean of infusions in LGA sessions1.52.73.8-1.61.9-1.6-1.71.91.7-1.7-1.71.7-1.9-1.7-1.11.91.6-2.01.20.31.6-1.5-1.61.81.5
Delay discount exponential model param0.10.10.30.10.20.10.1-0.1-0.10.10.2-0.10.10.10.3-0.2-0.30.1-0.40.5-0.40.50.4-0.10.0
Extinction: sum of active levers before priming2.94.44.9-2.22.0-2.1-2.22.12.2-2.2-2.12.2-2.2-2.2-2.12.12.2-2.02.11.02.2-2.2-2.02.22.0
Active lever presses in extinction session 63.33.34.5-1.82.1-1.8-1.81.91.8-1.8-1.91.8-2.0-1.8-1.91.71.8-1.71.82.01.7-1.6-1.21.82.0
Bone: final force1.82.94.4-1.81.4-1.7-1.71.61.6-1.6-1.71.7-1.8-1.7-2.11.51.9-1.42.11.31.8-1.9-1.51.71.9
Bone: final moment1.93.04.3-1.81.4-1.8-1.71.61.7-1.7-1.71.7-1.8-1.7-2.01.61.9-1.42.11.21.9-1.9-1.61.71.9
Food consumed during 24 hour testing period0.00.10.2-0.0-0.1-0.00.1-0.3-0.20.20.3-0.10.50.20.2-0.4-0.30.4-0.40.1-0.40.40.2-0.3-0.1
Glucose2.23.46.01.9-2.41.92.0-2.1-1.91.92.1-2.02.22.00.9-2.1-1.72.3-1.0-0.7-1.61.41.7-2.0-1.9
Heart weight0.30.42.20.4-1.50.60.6-0.7-0.50.50.7-0.70.80.60.0-0.5-0.20.90.2-1.1-0.0-0.2-0.2-0.6-0.8
Delay discount hyperbolic model param0.00.00.20.00.30.00.0-0.0-0.00.00.1-0.00.00.00.3-0.1-0.20.0-0.40.5-0.30.40.3-0.00.1
Intermittent access intake day 1-15 change0.31.83.01.3-0.91.41.4-1.5-1.41.41.4-1.61.41.50.9-1.7-1.41.5-1.10.9-1.61.71.7-1.0-0.5
Intermittent access intake escalation0.42.33.71.5-0.91.51.6-1.6-1.61.61.6-1.71.51.71.0-1.8-1.61.7-1.31.0-1.81.91.9-1.1-0.5
Intermittent access intake escalation 20.30.61.40.7-0.20.70.7-0.8-0.80.80.7-0.80.70.80.2-1.0-0.70.9-0.31.2-0.80.91.1-0.30.2
Intermitt. access day 1 inactive lever presses0.11.32.11.3-0.71.21.2-1.2-1.41.41.1-1.31.11.31.0-1.3-1.21.1-1.00.3-1.31.41.4-0.8-0.5
Intermitt. access day 15 inactive lever presses0.21.24.3-0.90.7-0.9-0.80.70.8-0.8-0.90.8-0.9-0.9-2.00.51.2-0.41.82.11.2-1.1-0.41.01.4
Intermitt. access escalation Index0.31.01.51.0-1.10.91.0-1.0-0.90.91.0-1.01.01.01.2-0.9-1.00.9-1.2-1.2-1.01.00.8-1.1-1.2
Intermittent access day 1 total infusions0.20.62.20.8-1.50.70.8-0.9-0.80.80.7-0.70.50.7-1.0-0.90.01.21.20.50.2-0.30.8-0.6-0.4
Intermittent access day 15 total infusions1.53.86.62.1-2.22.12.2-2.3-2.22.22.2-2.22.02.10.4-2.5-1.62.6-0.51.0-1.61.72.4-1.7-1.0
Intermittent access terminal intake (last 3 days)0.71.22.71.1-1.31.11.2-1.3-1.11.11.1-1.10.91.1-0.9-1.5-0.41.60.91.6-0.40.41.5-0.7-0.1
Intermittent access total infusions1.01.22.61.2-1.51.21.2-1.3-1.21.21.1-1.11.01.1-0.7-1.4-0.51.60.71.0-0.40.41.3-0.9-0.4
Intermittent access day 1 locomotion0.10.21.30.4-0.90.40.4-0.4-0.30.30.2-0.30.10.3-0.9-0.40.30.61.20.30.4-0.50.3-0.2-0.1
Intermittent access day 15 total locomotion0.10.42.20.6-0.50.60.5-0.5-0.40.40.4-0.40.20.4-1.2-0.70.20.81.21.50.2-0.10.9-0.00.4
Intermittent access total locomotion0.70.83.50.6-0.90.60.6-0.6-0.50.50.4-0.40.20.4-1.8-0.80.41.11.91.70.4-0.51.0-0.00.5
Intermittent access standard deviation0.21.01.51.1-0.81.11.1-1.1-1.11.11.1-1.21.01.10.5-1.2-1.01.2-0.60.5-1.01.11.2-0.9-0.5
Left kidney weight0.10.41.20.4-1.00.50.6-0.8-0.60.60.6-0.70.70.7-0.6-0.8-0.21.00.61.1-0.10.00.7-0.2-0.1
Right kidney weight0.00.21.20.2-0.60.20.4-0.5-0.40.40.4-0.40.60.5-0.4-0.6-0.10.80.41.1-0.10.00.5-0.1-0.0
Cocaine induced anxiety0.00.10.6-0.10.6-0.1-0.20.30.1-0.1-0.30.2-0.2-0.2-0.20.10.2-0.30.10.80.1-0.00.10.30.6
Post-drug Anxiety0.30.40.6-0.60.8-0.6-0.70.70.6-0.6-0.70.7-0.5-0.7-0.70.60.6-0.60.50.70.6-0.5-0.40.60.7
Baseline Anxiety0.20.40.9-0.60.2-0.6-0.70.60.6-0.6-0.50.7-0.5-0.7-0.30.70.6-0.60.4-0.70.7-0.7-0.90.3-0.1
Tail length0.21.02.4-1.31.1-1.4-1.21.11.0-1.0-1.11.0-0.9-0.90.11.20.7-1.3-0.1-0.80.7-0.7-1.60.80.5
Length with tail1.25.48.0-2.82.3-2.8-2.62.52.5-2.5-2.52.4-2.4-2.4-1.62.62.3-2.51.60.42.3-2.3-2.82.21.8
Length without tail1.78.711.3-3.32.8-3.3-3.23.13.2-3.2-3.13.1-3.0-3.0-2.43.23.0-3.12.40.53.0-3.0-3.42.82.3
Times rat made contact with spout0.20.21.4-0.40.3-0.4-0.30.30.3-0.3-0.20.3-0.1-0.30.40.40.1-0.5-0.6-1.20.1-0.1-0.80.3-0.1
Lifetime Intake0.80.92.41.1-1.61.11.1-1.2-1.11.11.0-1.00.91.0-0.4-1.2-0.51.40.50.4-0.30.31.0-0.9-0.7
Liver weight, left1.11.92.51.3-1.31.31.4-1.4-1.31.31.4-1.41.51.51.4-1.4-1.51.4-1.4-0.7-1.51.41.2-1.6-1.4
Liver weight, right1.52.64.51.5-2.11.51.7-1.8-1.61.61.6-1.71.71.71.4-1.6-1.51.8-1.2-1.6-1.41.30.9-1.7-1.8
Locomotor activity1.11.86.61.1-1.31.11.1-1.1-1.11.11.2-1.11.31.21.8-0.8-1.30.9-1.8-2.6-1.21.10.2-1.5-1.8
Locomotor testing distance0.92.18.41.2-1.61.31.2-1.2-1.21.21.2-1.31.31.21.8-0.9-1.41.0-1.7-2.9-1.21.10.2-1.8-2.0
Locomotor testing rearing0.62.05.01.2-1.61.21.3-1.3-1.31.31.3-1.41.41.21.7-1.1-1.41.2-1.6-2.2-1.31.20.4-1.8-1.9
Locomotion in novel chamber1.62.23.41.7-1.61.71.6-1.7-1.61.61.6-1.61.71.60.7-1.7-1.31.8-0.70.2-1.31.31.8-1.5-1.1
Locomotion in novel chamber post-restriction0.92.64.31.8-1.41.91.8-1.7-1.71.71.8-1.81.81.81.2-1.8-1.71.7-1.30.2-1.71.72.1-1.1-1.0
Fecal boli incidents, locomotor time 10.10.32.20.4-0.00.40.4-0.4-0.40.40.4-0.40.40.4-0.1-0.6-0.40.60.01.5-0.50.61.0-0.20.2
Change in fecal boli incidents, locomotor task1.31.43.81.2-1.51.21.2-1.2-1.21.21.2-1.21.21.21.2-1.0-1.11.0-1.1-1.9-1.00.90.5-1.1-1.3
Time >=10cm from walls, locomotor time 11.41.74.31.4-1.21.41.4-1.5-1.51.51.4-1.31.31.30.1-1.7-1.11.7-0.11.3-1.11.22.1-0.9-0.4
Bouts of movement, locomotor time 10.20.31.8-0.31.3-0.2-0.50.60.2-0.2-0.50.5-0.5-0.50.40.50.0-0.9-0.60.5-0.20.30.10.50.7
Total resting periods, locomotor time 10.20.31.5-0.31.2-0.3-0.50.60.3-0.3-0.50.5-0.5-0.50.20.40.1-0.7-0.40.8-0.10.20.10.50.7
Rest time, locomotor task time 11.21.92.71.3-1.11.41.4-1.4-1.21.21.5-1.51.51.51.4-1.5-1.61.4-1.5-0.2-1.61.61.4-1.2-1.0
Distance moved, locomotor task time 10.10.40.7-0.60.3-0.6-0.60.60.6-0.6-0.60.6-0.6-0.6-0.80.60.7-0.50.90.00.8-0.8-0.60.40.3
Vertical activity count, locomotor time 10.10.50.70.8-0.80.80.8-0.8-0.80.80.7-0.70.70.70.6-0.7-0.70.7-0.5-0.6-0.60.60.6-0.7-0.7
Time >=10cm from walls, locomotor time 20.10.11.80.10.30.10.1-0.1-0.10.10.1-0.10.10.1-0.2-0.3-0.20.20.11.3-0.30.40.80.10.4
Bouts of movement, locomotor time 20.41.31.8-1.31.3-1.3-1.31.31.3-1.3-1.31.2-1.2-1.2-0.91.21.1-1.30.80.61.1-1.0-1.11.01.0
Total resting periods, locomotor time 20.20.60.9-0.90.9-0.9-0.90.90.9-0.9-0.80.8-0.8-0.8-0.60.80.8-0.80.60.50.7-0.7-0.70.70.7
Rest time, locomotor task time 22.23.74.42.0-1.92.02.1-2.1-2.02.02.1-2.12.12.11.7-2.0-2.02.0-1.7-0.9-2.01.91.9-1.7-1.5
Distance moved, locomotor task time 20.40.61.2-0.81.1-0.9-0.90.90.9-0.9-0.90.8-0.8-0.8-0.30.90.6-1.00.30.20.6-0.5-0.80.60.5
Vertical activity count, locomotor time 20.10.21.40.10.10.10.00.0-0.10.10.1-0.00.00.00.80.1-0.3-0.2-0.9-1.2-0.30.3-0.3-0.2-0.4
Light reinforcement 10.00.10.30.1-0.10.00.1-0.2-0.10.10.2-0.20.30.30.6-0.2-0.30.2-0.5-0.0-0.40.40.1-0.2-0.2
Light reinforcement 20.20.57.10.1-0.00.10.2-0.4-0.30.30.2-0.30.40.3-0.8-0.6-0.00.60.62.7-0.20.21.00.00.4
Bone: marrow area0.92.14.71.5-2.21.51.6-1.8-1.51.51.6-1.51.61.6-0.4-1.8-0.92.20.40.9-0.90.71.7-1.3-1.2
Bone: maximum diameter0.30.52.7-0.50.4-0.5-0.40.30.5-0.5-0.50.4-0.5-0.3-1.40.20.7-0.11.31.60.7-0.70.00.91.1
Bone: maximum force2.65.19.5-2.31.7-2.3-2.22.02.2-2.2-2.22.1-2.2-2.1-3.11.92.5-1.63.12.22.5-2.6-1.82.22.4
Bone: maximum moment2.75.19.0-2.31.7-2.3-2.22.02.2-2.2-2.22.2-2.2-2.2-3.01.92.5-1.63.02.12.5-2.6-1.92.22.4
Mean time between licks in bursts0.10.52.6-0.70.0-0.6-0.60.60.6-0.6-0.50.7-0.4-0.50.10.80.5-0.6-0.1-1.60.6-0.7-1.60.0-0.5
Mean num. licks in bursts0.00.11.00.3-0.00.30.2-0.1-0.10.10.2-0.20.10.10.7-0.1-0.3-0.0-0.7-1.0-0.30.4-0.0-0.1-0.2
Cd content in liver0.70.82.11.1-0.71.21.0-0.9-0.90.91.0-0.90.80.90.4-1.0-0.80.9-0.40.3-0.90.91.4-0.5-0.4
Co content in liver1.21.44.31.1-0.81.11.0-0.9-1.01.01.0-1.00.91.01.9-0.8-1.30.6-1.8-2.1-1.31.30.5-1.0-1.1
Cu content in liver0.00.00.30.10.00.10.1-0.0-0.10.10.1-0.10.10.00.50.0-0.2-0.1-0.4-0.6-0.20.20.10.10.2
Fe content in liver0.00.00.10.3-0.20.30.2-0.1-0.10.10.2-0.20.10.10.1-0.1-0.10.1-0.0-0.1-0.10.10.3-0.2-0.4
K content in liver0.40.40.9-0.90.3-0.8-0.70.50.5-0.5-0.70.6-0.6-0.6-0.80.60.7-0.40.80.40.8-0.8-0.90.60.5
Mg content in liver0.10.10.3-0.1-0.4-0.1-0.0-0.00.0-0.0-0.1-0.0-0.0-0.0-0.20.10.20.10.4-0.60.3-0.4-0.50.30.1
Mn content in liver3.43.84.7-2.22.0-2.1-2.12.02.0-2.0-2.02.0-1.9-2.0-2.01.92.0-1.81.81.62.0-1.9-1.72.01.9
Na content in liver0.40.50.8-0.80.5-0.8-0.70.60.7-0.7-0.80.6-0.7-0.6-0.80.60.8-0.50.90.80.7-0.7-0.70.50.5
Rb content in liver2.93.34.31.7-2.11.81.9-1.9-2.02.01.8-1.91.92.01.9-1.8-1.91.8-1.8-1.6-1.81.71.2-1.8-1.9
Se content in liver0.20.22.3-0.40.4-0.3-0.30.20.3-0.3-0.30.2-0.3-0.3-0.80.10.4-0.10.71.50.4-0.40.10.40.5
Sr content in liver4.33.74.7-2.02.2-2.0-2.12.12.0-2.0-2.12.0-2.0-2.0-1.72.12.0-2.11.50.81.9-1.8-1.82.01.7
Zn content in liver2.63.14.5-1.71.7-1.6-1.71.81.8-1.8-1.81.8-1.9-1.8-1.61.91.9-1.91.70.31.9-1.9-1.62.11.8
Bone: minimum diameter0.40.92.30.7-1.40.80.9-1.1-0.90.91.0-0.91.00.9-0.9-1.2-0.31.50.71.4-0.30.11.1-0.6-0.6
Time in familiar zone, hab. session 10.10.10.3-0.20.0-0.2-0.30.20.4-0.4-0.20.3-0.1-0.3-0.50.20.4-0.10.50.00.4-0.4-0.3-0.10.1
Time in novel zone, hab. session 11.41.62.41.2-1.21.21.2-1.2-1.31.31.3-1.31.21.31.5-1.1-1.41.1-1.5-1.0-1.31.30.8-1.3-1.4
Total zone transitions, hab. session 10.20.20.4-0.50.5-0.5-0.50.60.4-0.4-0.50.5-0.6-0.5-0.30.60.5-0.60.3-0.30.5-0.5-0.50.50.4
Total locomotion distance, hab. session 10.10.10.40.4-0.40.40.3-0.3-0.30.30.2-0.30.00.3-0.4-0.30.00.30.60.50.1-0.10.60.20.3
Locomotion velocity, hab. session 10.20.20.8-0.20.3-0.3-0.30.30.2-0.2-0.40.3-0.5-0.3-0.80.30.5-0.30.90.60.5-0.50.00.80.9
Time in familiar zone, hab. session 20.40.51.80.4-0.50.30.3-0.5-0.30.30.6-0.30.80.41.2-0.4-0.80.5-1.4-1.1-0.80.8-0.1-0.8-0.7
Time in novel zone, hab. session 20.50.61.7-0.60.4-0.6-0.60.70.6-0.6-0.70.6-0.9-0.6-1.10.70.9-0.61.30.51.0-1.0-0.50.70.6
Total zone transitions, hab. session 21.31.62.4-1.30.8-1.2-1.31.31.2-1.2-1.31.3-1.4-1.3-1.21.31.4-1.21.4-0.61.4-1.5-1.61.31.2
Total locomotion distance, hab. session 20.20.20.7-0.3-0.0-0.3-0.30.30.2-0.2-0.40.3-0.5-0.3-0.60.30.5-0.20.9-0.40.6-0.7-0.50.60.8
Locomotion velocity, hab. session 20.10.10.8-0.1-0.2-0.1-0.10.10.0-0.0-0.20.1-0.4-0.1-0.70.10.4-0.00.9-0.00.5-0.5-0.20.60.7
Novel to familiar place preference ratio1.82.43.2-1.61.6-1.6-1.61.61.4-1.4-1.51.5-1.6-1.5-1.71.51.6-1.51.71.31.6-1.6-1.11.81.6
Novelty place preference1.21.52.2-1.31.3-1.3-1.21.21.1-1.1-1.21.2-1.2-1.2-1.41.11.3-1.11.31.21.2-1.2-0.81.51.3
Time in novel zone, NPP test1.31.52.1-1.31.2-1.3-1.31.21.1-1.1-1.21.2-1.2-1.2-1.41.21.3-1.21.31.11.3-1.3-0.91.41.2
Total zone transitions, NPP test0.91.42.1-1.11.0-1.1-1.11.31.1-1.1-1.31.2-1.5-1.2-0.91.31.3-1.31.2-0.71.3-1.3-1.31.21.2
Total locomotion distance, NPP test0.10.10.7-0.0-0.10.0-0.00.2-0.00.0-0.30.1-0.5-0.1-0.20.30.3-0.30.6-0.90.4-0.4-0.30.40.6
Locomotion velocity, NPP test0.10.10.60.1-0.00.10.10.1-0.10.1-0.2-0.0-0.40.0-0.00.20.2-0.20.4-0.80.2-0.2-0.10.30.5
Intraocular pressure0.10.20.70.30.10.30.3-0.3-0.30.30.3-0.30.40.30.6-0.3-0.50.2-0.80.0-0.60.70.4-0.20.1
Delta distance traveled before/after self-admin0.70.72.70.7-0.70.90.7-0.6-0.60.60.9-0.60.90.61.3-0.5-0.90.5-1.4-1.6-0.80.80.2-0.8-1.1
Delta ambulatory time before/after self-admin0.71.22.90.9-0.91.00.9-0.9-0.90.91.1-0.91.10.91.6-0.7-1.20.7-1.7-1.7-1.11.10.4-1.0-1.3
Parametrial fat weight1.22.95.51.7-2.11.81.9-2.0-1.71.71.9-2.01.92.00.0-2.2-1.32.4-0.11.1-1.31.22.2-1.4-1.1
Pavlov. Cond. lever latency1.11.32.81.1-0.81.21.1-1.0-1.11.11.1-1.11.11.11.5-1.0-1.30.8-1.7-1.1-1.31.30.9-0.8-1.2
Pavlov. Cond. magazine entry latency1.41.84.4-1.21.1-1.3-1.21.11.3-1.3-1.21.3-1.2-1.3-1.90.91.4-0.82.02.11.4-1.3-0.61.11.6
Pavlov. Cond. change in total contacts0.70.83.4-0.60.8-0.7-0.60.60.7-0.7-0.70.7-0.7-0.7-1.30.40.8-0.41.41.80.7-0.70.20.81.5
Pavlov. Cond. index score0.91.12.4-1.01.0-1.1-1.00.91.1-1.1-1.01.1-1.0-1.1-1.40.81.1-0.81.41.61.0-1.0-0.50.81.3
Pavlov. Cond. latency score0.70.91.9-0.90.8-1.0-0.90.81.0-1.0-0.90.9-0.9-0.9-1.30.71.0-0.61.41.31.0-1.0-0.60.61.1
Pavlov. Cond. lever contacts0.50.71.8-0.80.4-0.8-0.70.70.8-0.8-0.80.8-0.8-0.8-1.20.60.9-0.51.30.90.9-1.0-0.60.50.8
Pavlov. Cond. magazine entry number1.01.32.81.0-1.31.11.1-1.1-1.21.21.1-1.21.11.21.3-0.9-1.11.0-1.3-1.7-1.00.90.4-0.9-1.5
Pavlov. Cond. intertrial magazine entries0.10.10.9-0.20.8-0.1-0.20.30.1-0.1-0.30.2-0.4-0.20.00.20.1-0.4-0.00.8-0.00.10.30.60.9
Pavlov. Cond. lever-magazine prob. diff.1.01.33.0-1.01.1-1.1-1.11.01.1-1.1-1.11.1-1.0-1.1-1.50.81.2-0.81.51.71.1-1.0-0.40.91.4
Pavlov. Cond. response bias1.21.53.1-1.11.2-1.3-1.21.11.2-1.2-1.21.2-1.2-1.2-1.50.91.3-0.91.61.81.2-1.1-0.61.01.6
Pavlov. Cond. lever latency0.60.91.51.0-0.81.01.0-0.8-1.11.10.9-1.00.81.01.2-0.7-1.00.6-1.1-0.8-0.90.90.7-0.9-0.9
Pavlov. Cond. magazine entry latency4.76.77.8-2.72.8-2.7-2.72.72.7-2.7-2.72.8-2.8-2.8-2.42.62.6-2.62.41.72.5-2.4-2.22.42.7
Pavlov. Cond. change in total contacts1.02.53.7-1.61.7-1.6-1.61.51.8-1.8-1.51.7-1.5-1.7-1.91.31.6-1.21.81.91.5-1.4-0.91.51.8
Pavlov. Cond. index score2.74.25.4-2.12.1-2.1-2.12.02.2-2.2-2.12.2-2.1-2.2-2.31.82.1-1.82.22.02.0-1.9-1.51.92.2
Pavlov. Cond. latency score2.43.95.3-2.02.0-2.0-2.01.92.1-2.1-2.02.0-2.0-2.0-2.31.72.1-1.62.22.11.9-1.9-1.31.82.2
Pavlov. Cond. lever contacts0.50.81.2-0.90.8-0.9-0.90.81.0-1.0-0.81.0-0.8-0.9-1.10.70.9-0.60.90.90.8-0.8-0.60.81.0
Pavlov. Cond. magazine entry number7.910.212.03.3-3.53.33.4-3.3-3.43.43.4-3.43.43.43.1-3.2-3.33.2-3.0-2.2-3.13.02.6-3.0-3.2
Pavlov. Cond. intertrial magazine entries1.02.22.91.6-1.31.61.6-1.5-1.51.51.6-1.71.51.61.4-1.6-1.61.4-1.4-0.3-1.61.61.7-1.1-1.1
Pavlov. Cond. lever-magazine prob. diff.3.14.85.8-2.32.3-2.2-2.32.22.4-2.4-2.22.3-2.2-2.3-2.42.02.3-1.92.32.02.1-2.0-1.62.02.3
Pavlov. Cond. response bias2.23.13.9-1.91.7-1.9-1.91.72.0-2.0-1.81.9-1.7-1.9-1.91.61.8-1.51.71.21.7-1.7-1.51.51.7
Time in closed arm before self-admin0.10.11.70.0-0.0-0.10.1-0.2-0.10.10.1-0.10.30.1-0.5-0.4-0.00.40.31.3-0.10.10.5-0.10.2
Time in closed arm after self-admin0.91.01.60.9-1.20.81.0-1.0-1.01.01.0-1.01.21.00.9-0.9-1.01.0-1.0-0.9-0.90.90.6-1.2-1.2
Time in open arm before self-admin1.51.910.41.2-1.51.21.1-1.0-1.11.11.1-1.11.11.11.9-0.7-1.20.7-1.7-3.2-1.00.90.1-1.2-1.8
Time in open arm after self-admin0.40.40.9-0.60.7-0.4-0.60.80.7-0.7-0.70.7-0.9-0.7-0.20.90.6-0.90.3-0.50.6-0.6-0.80.80.5
Bone: periosteal estimation0.20.43.0-0.1-0.4-0.10.0-0.20.0-0.00.1-0.00.00.0-1.4-0.30.50.61.41.70.4-0.60.40.30.4
Bone: periosteal perimeter0.10.32.8-0.2-0.1-0.1-0.0-0.10.1-0.1-0.0-0.0-0.00.0-1.1-0.30.40.41.11.70.3-0.30.40.30.5
Bone: post-yield work0.40.74.20.2-0.60.20.2-0.30.0-0.00.2-0.10.20.1-1.9-0.50.50.91.92.10.5-0.60.80.51.1
Progressive ratio test 1 active lever presses0.20.40.70.9-0.70.90.8-0.7-0.80.80.7-0.70.50.70.0-0.7-0.40.70.10.5-0.40.40.8-0.5-0.3
Progressive ratio test 1 breakpoint0.20.40.70.8-0.70.80.8-0.7-0.80.80.7-0.70.50.7-0.0-0.7-0.40.70.10.6-0.40.40.9-0.5-0.2
Progressive ratio test 1 inactive lever presses0.30.81.9-0.80.7-0.8-0.80.80.7-0.7-0.90.9-0.9-0.8-1.30.81.0-0.71.41.11.1-1.1-0.70.80.9
Progressive ratio test 2 active lever presses0.60.91.91.1-0.91.11.0-1.0-1.01.01.0-1.00.80.9-0.4-1.2-0.51.20.31.3-0.50.61.4-0.6-0.1
Progressive ratio test 2 breakpoint0.60.81.71.0-0.91.11.0-1.0-0.90.90.9-0.90.70.9-0.4-1.2-0.51.20.41.3-0.50.51.3-0.6-0.1
Progressive ratio test 2 inactive lever presses0.20.62.30.8-0.70.80.8-0.8-0.80.80.7-0.70.60.7-0.7-1.0-0.31.10.71.5-0.30.41.2-0.40.1
Incentive Sensitization - Responses0.41.03.3-0.80.6-0.8-0.80.70.9-0.9-0.80.8-0.8-0.8-1.80.61.2-0.51.71.71.1-1.1-0.40.91.2
Incentive Sensitization - Breakpoint0.40.83.0-0.60.5-0.6-0.60.60.8-0.8-0.70.7-0.7-0.7-1.70.41.0-0.31.61.71.0-1.0-0.30.81.1
Sum of active levers in priming session hrs 5-61.61.56.1-1.01.9-1.0-1.11.11.1-1.1-1.11.1-1.2-1.1-1.00.80.9-1.10.82.50.6-0.4-0.11.51.9
Progressive ratio0.00.10.9-0.1-0.3-0.1-0.0-0.20.0-0.00.00.10.10.0-0.9-0.20.30.40.80.90.3-0.30.20.00.1
Food seeking constrained by brief footshock0.10.10.30.2-0.40.20.2-0.2-0.30.30.3-0.20.20.20.3-0.2-0.20.2-0.2-0.6-0.10.10.0-0.3-0.5
Seeking ratio, punishment vs. effort0.10.32.90.3-0.30.30.2-0.1-0.20.20.2-0.20.10.10.90.1-0.3-0.2-0.7-1.7-0.20.2-0.4-0.3-0.6
Retroperitoneal fat weight3.314.620.74.0-4.63.94.2-4.3-4.24.24.1-4.24.24.32.6-4.3-3.74.4-2.4-1.1-3.53.43.7-3.7-3.5
Reaction time number correct0.20.51.7-1.10.6-1.0-0.90.80.9-0.9-0.70.9-0.6-0.7-0.30.80.6-0.70.2-0.40.6-0.6-1.30.10.1
Reaction time mean minus median0.10.93.8-0.81.6-0.8-0.90.90.9-0.9-0.80.9-0.7-0.9-1.00.60.7-0.80.72.00.5-0.30.21.21.4
Reaction time mean minus median AUC0.00.31.3-0.41.1-0.4-0.50.50.5-0.5-0.40.5-0.3-0.5-0.10.30.2-0.6-0.10.90.00.20.10.70.7
Reaction time num false alarms0.50.85.90.8-0.70.90.7-0.5-0.50.50.6-0.60.40.61.5-0.3-0.80.2-1.3-2.4-0.70.6-0.0-1.0-1.3
Reaction time num false alarms AUC0.20.55.90.3-0.20.30.20.10.1-0.10.1-0.1-0.10.11.20.3-0.3-0.4-1.1-2.4-0.20.2-0.6-0.5-1.0
Reaction time trials correct on left0.20.51.7-1.10.6-1.0-0.90.80.9-0.9-0.70.9-0.6-0.7-0.30.80.6-0.70.2-0.40.6-0.6-1.30.10.1
Reaction time trials on left0.20.61.8-1.10.6-1.0-0.90.80.9-0.9-0.80.9-0.6-0.8-0.20.90.6-0.80.2-0.50.6-0.7-1.30.10.1
Reaction time mean0.10.11.20.30.50.30.10.00.1-0.10.10.1-0.0-0.1-0.2-0.2-0.10.00.01.1-0.20.40.90.30.5
Reaction time mean AUC0.10.21.10.30.30.30.2-0.2-0.10.10.2-0.10.20.1-0.0-0.4-0.30.2-0.11.1-0.40.60.90.10.3
Median of all reaction times0.10.10.60.30.30.30.10.00.1-0.10.10.0-0.1-0.1-0.2-0.2-0.00.10.10.8-0.10.20.70.20.4
Reaction time omissions0.30.41.4-0.61.2-0.5-0.70.80.8-0.8-0.70.8-0.7-0.8-0.20.70.5-0.90.10.30.4-0.2-0.30.80.7
Reaction time false alarm rate0.40.63.30.9-0.60.90.7-0.4-0.50.50.6-0.60.30.51.1-0.3-0.60.2-1.0-1.8-0.50.50.3-0.6-1.0
Reaction time premature initiation rate3.45.310.0-2.61.6-2.6-2.42.42.5-2.5-2.42.3-2.2-2.5-1.92.52.5-2.32.0-0.22.6-2.7-3.21.81.4
Reaction time premature initiations2.26.613.6-3.12.1-3.0-2.92.72.9-2.9-2.72.7-2.5-2.7-1.72.92.6-2.71.8-0.52.7-2.8-3.71.81.4
Std. dev. reaction times0.10.21.00.30.80.30.10.00.1-0.10.20.00.1-0.00.2-0.2-0.3-0.1-0.41.0-0.40.60.90.30.5
Reaction time trials completed0.20.61.8-1.10.6-1.0-0.90.80.9-0.9-0.80.9-0.6-0.8-0.20.90.6-0.80.2-0.50.6-0.7-1.30.10.1
Reaction time trials AUC0.10.51.6-1.00.4-0.9-0.80.70.8-0.8-0.70.8-0.5-0.7-0.20.80.5-0.60.1-0.50.6-0.6-1.3-0.0-0.0
Run reversals in cocaine runway, females0.40.41.7-0.5-0.3-0.5-0.50.40.5-0.5-0.50.5-0.6-0.5-0.60.60.7-0.40.8-1.30.9-1.1-1.00.2-0.2
Run reversals in cocaine runway, males0.50.50.90.7-0.50.70.7-0.7-0.80.80.7-0.70.70.71.0-0.6-0.80.6-0.9-0.5-0.80.80.6-0.6-0.8
Latency to leave start box in cocaine runway0.30.41.00.6-1.00.70.7-0.8-0.60.60.7-0.70.70.7-0.1-0.8-0.40.90.00.1-0.40.30.6-0.5-0.4
Latency to leave start box in cocaine runway, F0.00.10.2-0.2-0.0-0.2-0.20.10.2-0.2-0.20.1-0.2-0.1-0.50.10.3-0.00.40.30.3-0.3-0.30.20.3
Latency to leave start box in cocaine runway, M2.01.92.91.5-1.71.51.6-1.6-1.51.51.6-1.51.51.50.8-1.6-1.31.7-0.8-0.3-1.31.21.4-1.3-1.1
Std. dev. time between licks in bursts0.20.32.30.2-0.70.20.2-0.3-0.30.30.4-0.20.50.30.7-0.1-0.40.3-0.8-1.5-0.30.2-0.6-0.6-0.9
Total sessions with >9 infusions0.70.91.51.1-1.21.11.1-1.1-1.01.01.0-1.10.91.00.5-1.1-0.81.1-0.3-0.1-0.70.70.9-1.0-0.8
Short access day 1 total inactive lever presses0.00.10.40.4-0.60.40.2-0.2-0.10.10.2-0.00.20.1-0.5-0.20.10.30.6-0.20.2-0.20.2-0.3-0.3
Short access day 10 total inactive lever presses0.10.71.00.9-0.80.90.8-0.8-0.80.80.8-0.80.80.91.0-0.8-0.90.7-0.9-1.0-0.90.90.7-0.8-0.8
Short access day 1 total infusions0.81.52.81.4-1.71.31.4-1.4-1.31.31.3-1.31.21.30.6-1.4-1.11.5-0.4-0.4-0.90.91.1-1.4-1.2
Short access day 10 total infusions0.20.41.40.6-1.20.60.6-0.7-0.60.60.6-0.60.50.6-0.7-0.7-0.00.90.90.50.1-0.20.5-0.5-0.4
Short access total infusions0.50.82.41.0-1.60.91.0-1.0-1.01.00.9-0.90.80.90.0-1.0-0.51.20.3-0.4-0.30.20.6-1.0-1.0
Short access day 1 locomotion0.20.30.60.6-0.80.60.6-0.6-0.60.60.6-0.50.50.6-0.2-0.6-0.30.70.20.4-0.20.20.6-0.5-0.3
Short access day 10 total locomotion0.10.31.8-0.0-0.3-0.0-0.00.00.1-0.1-0.20.1-0.20.0-1.2-0.10.60.21.31.00.6-0.70.10.30.5
Short access total locomotion0.10.20.70.5-0.70.50.4-0.4-0.40.40.3-0.40.20.4-0.7-0.50.10.60.80.60.2-0.20.5-0.20.1
One hour access (0.3 mA shock)0.91.02.01.2-1.31.21.2-1.2-1.11.11.0-1.21.01.2-0.2-1.3-0.71.40.20.6-0.60.61.3-0.8-0.4
Compulsive drug intake0.50.81.8-1.00.9-1.1-1.01.01.1-1.1-0.80.9-0.8-0.90.41.20.5-1.2-0.3-1.20.5-0.5-1.30.50.1
One hour access (shock baseline)1.33.45.82.1-2.02.12.1-2.1-2.22.21.9-2.11.82.10.3-2.3-1.52.4-0.31.2-1.51.52.4-1.4-0.8
Social response proportion0.00.10.4-0.50.1-0.5-0.30.10.1-0.1-0.30.1-0.0-0.2-0.00.20.1-0.10.0-0.30.1-0.1-0.6-0.0-0.0
Social responses0.10.11.0-0.40.4-0.4-0.30.20.2-0.2-0.20.1-0.1-0.20.60.3-0.1-0.4-0.7-1.0-0.10.2-0.60.1-0.2
Social time0.10.21.4-0.00.1-0.10.1-0.0-0.10.10.1-0.20.20.10.70.1-0.4-0.2-0.9-1.2-0.30.4-0.30.0-0.3
Soleus weight3.08.910.23.1-3.13.13.1-3.1-3.23.23.1-3.13.03.22.7-3.1-3.13.0-2.6-1.3-3.02.92.8-3.2-3.2
Bone: stiffness0.81.54.0-1.21.1-1.2-1.11.01.0-1.0-1.11.1-1.1-1.0-1.70.81.2-0.71.62.01.1-1.1-0.61.31.7
Tibialis anterior weight8.830.434.5-5.95.7-5.9-5.85.95.8-5.8-5.95.8-5.8-5.7-4.85.85.7-5.84.62.25.6-5.5-5.25.85.1
Time to tail flick, vehicle, before self-admin0.20.31.3-0.30.1-0.3-0.30.30.4-0.4-0.40.3-0.4-0.4-1.10.20.6-0.11.10.80.7-0.7-0.10.50.6
Time to tail flick, vehicle, after self-admin0.10.30.7-0.40.1-0.5-0.40.50.5-0.5-0.50.5-0.5-0.6-0.70.50.7-0.40.7-0.20.8-0.8-0.60.30.1
Time to tail flick, test, before self-admin0.30.41.2-0.4-0.4-0.3-0.40.30.5-0.5-0.30.5-0.3-0.4-1.00.50.8-0.21.1-0.60.9-1.1-0.70.50.1
Time to tail flick, test, after self-admin0.10.10.5-0.20.3-0.3-0.20.20.2-0.2-0.20.2-0.1-0.2-0.40.10.2-0.10.30.70.1-0.10.10.30.4
Delta time to tail flick, vehicle, before/after SA0.20.20.4-0.40.3-0.4-0.40.40.3-0.3-0.40.4-0.5-0.4-0.10.50.4-0.50.2-0.60.4-0.5-0.70.20.0
Delta time to tail flick, test, before/after SA0.10.21.2-0.11.0-0.2-0.20.20.1-0.1-0.20.1-0.2-0.10.40.0-0.3-0.3-0.51.1-0.50.60.40.20.5
Tibia length1.84.99.6-2.22.4-2.1-2.12.02.0-2.0-2.22.0-2.2-2.0-2.61.82.2-1.82.62.82.1-2.0-1.02.83.1
Ambulatory time before self-admin0.92.74.7-1.61.8-1.6-1.61.61.6-1.6-1.61.6-1.7-1.7-2.01.41.7-1.41.92.21.6-1.5-0.91.61.8
Ambulatory time after self-admin0.20.20.8-0.40.6-0.4-0.50.50.5-0.5-0.30.6-0.3-0.6-0.70.40.5-0.30.40.90.4-0.4-0.10.50.5
Bone: tissue strength0.40.40.80.3-0.70.30.5-0.7-0.60.60.6-0.60.70.60.7-0.6-0.70.7-0.8-0.6-0.70.60.0-0.9-0.8
Total heroin consumption5.76.710.0-2.73.2-2.7-2.82.92.7-2.7-2.82.7-2.9-2.7-1.82.82.5-3.01.81.02.3-2.2-2.42.92.7
Bone: trabecular number1.01.93.6-1.30.9-1.3-1.31.21.4-1.4-1.31.4-1.2-1.4-1.91.21.6-1.01.91.11.6-1.7-1.11.21.2
Bone: trabecular spacing0.60.92.70.8-0.70.70.8-0.8-0.90.90.8-0.90.80.91.6-0.7-1.10.6-1.5-1.4-1.11.20.3-1.0-0.8
Bone: trabecular thickness0.10.21.00.4-0.20.40.3-0.4-0.30.30.4-0.20.40.2-0.3-0.5-0.20.50.01.0-0.30.30.8-0.4-0.2
Bone: trabecular tissue density4.37.59.53.0-2.33.02.9-2.7-2.92.92.8-2.92.62.93.0-2.8-3.02.5-2.8-1.2-3.03.12.8-2.4-2.3
Water consumed over 24 hours0.30.61.6-1.10.8-1.1-1.00.90.9-0.9-0.80.9-0.6-0.9-0.30.90.7-0.90.0-0.40.7-0.6-1.30.50.2
Number of responses in last shaping day0.10.10.4-0.30.2-0.4-0.30.40.3-0.3-0.40.3-0.4-0.30.00.50.3-0.50.2-0.50.4-0.4-0.60.1-0.1