Hub : Genes

Atp8b5p

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Atp8b5p 0.16 0.09 9.3e-14 0.15 0.09 0.15 0.15 4.1e-14 5.1e-09 3.5e-14 1.2e-13
2 Liver gene expression Atp8b5p 0.34 0.14 0.0e+00 0.29 0.32 0.32 0.32 6.2e-32 4.2e-36 9.1e-37 6.6e-37
3 IL alternative TSS XM_039110991.2 0.15 0.13 3.0e-03 0.11 0.03 0.07 0.06 1.4e-03 7.5e-02 7.8e-03 1.5e-02
4 IL gene expression Atp8b5p 0.13 0.09 2.1e-03 0.15 0.1 0.06 0.12 1.9e-04 2.8e-03 1.5e-02 6.6e-04
5 Liver mRNA stability Atp8b5p 0.14 0.09 3.9e-16 0.11 0.14 0.14 0.14 2.1e-12 7.2e-15 4.2e-15 3.4e-15
6 Eye gene expression Atp8b5p 0.28 0.18 7.4e-03 0.1 0.07 0.09 0.03 1.2e-02 3.3e-02 1.9e-02 1.4e-01
7 BLA gene expression Atp8b5p 0.14 0.09 9.5e-07 0.14 0.1 0.13 0.13 1.1e-07 5.3e-06 2.9e-07 3.3e-07
8 Liver alternative polyA XM_039110995.2 0.04 0.03 3.7e-05 0.02 0.04 0.03 0.03 8.9e-04 5.6e-05 3.6e-04 2.4e-04
9 Adipose mRNA stability Atp8b5p 0.09 0.05 2.8e-11 0.07 0.09 0.09 0.09 2.3e-08 3.3e-10 7.1e-10 8.7e-10
10 Liver alternative polyA XM_039110987.2 0.06 0.04 5.3e-08 0.04 0.07 0.06 0.06 9.7e-06 7.5e-08 1.0e-06 4.5e-07
11 Adipose gene expression Atp8b5p 0.26 0.14 0.0e+00 0.23 0.23 0.24 0.24 1.0e-25 1.2e-25 2.3e-26 1.8e-26
12 LHb gene expression Atp8b5p 0.12 0.09 7.4e-03 0.06 0.06 0.02 0.04 1.9e-02 1.5e-02 1.0e-01 3.2e-02
13 PL gene expression Atp8b5p 0.07 0.05 1.0e-09 0.11 0.09 0.1 0.1 1.1e-11 4.9e-10 3.1e-11 2.5e-11
14 pVTA gene expression Atp8b5p 0.1 0.07 1.1e-08 0.09 0.09 0.08 0.06 2.1e-07 1.5e-07 8.4e-07 6.6e-06
15 Adipose alternative polyA XM_039110995.2 0.02 0.01 5.6e-03 0.01 0.01 0 0.01 9.1e-03 4.2e-02 1.3e-01 2.8e-02
16 PL alternative polyA XM_039110987.2 0.03 0.02 5.2e-04 0.03 0.03 0.03 0.03 3.2e-04 2.3e-04 2.5e-04 2.4e-04
17 Liver alternative polyA XM_039110987.2 0.03 0.02 3.2e-04 0.02 0.03 0.03 0.03 9.6e-04 2.0e-04 7.1e-04 6.7e-04
18 Brain mRNA stability Atp8b5p 0.06 0.04 8.4e-06 0.06 0.02 0.06 -0 4.0e-06 6.9e-03 6.7e-06 8.7e-01
19 Adipose alternative TSS XM_039110987.2 0.03 0.02 5.0e-04 0.04 0.03 0.04 0.04 6.6e-05 2.4e-04 2.0e-05 5.7e-05
20 NAcc gene expression Atp8b5p 0.13 0.08 0.0e+00 0.15 0.09 0.15 0.03 1.1e-22 4.0e-13 1.7e-22 2.7e-05
21 Adipose alternative TSS XM_039110987.2 0.02 0.02 4.4e-03 0.02 0.02 0.02 0.02 1.3e-03 3.0e-03 3.9e-03 1.1e-03
22 LHb alternative polyA XM_039110987.2 0.11 0.08 5.3e-03 0.08 0.06 0.05 0.05 6.5e-03 1.9e-02 3.0e-02 2.9e-02
23 OFC alternative polyA XM_039110995.2 0.17 0.12 3.8e-03 0.02 0.02 0 0.03 1.2e-01 9.4e-02 2.4e-01 7.5e-02
24 Liver intron excision ratio chr5_62379025_62393199 0.04 0.03 3.9e-03 0 0 0.01 -0 2.1e-01 2.7e-01 3.3e-02 3.8e-01
25 Liver intron excision ratio chr5_62345071_62360249 0.09 0.06 5.4e-08 0.02 0.06 0.06 0.05 1.1e-03 4.0e-07 6.2e-07 1.1e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density1.42.63.4-1.51.61.4-1.51.7-1.3-1.2-1.61.61.61.81.7-1.51.7-1.81.81.8-1.80.8-1.71.9-1.7-1.81.7-1.5
Area under the delay curve0.50.82.40.8-0.9-0.60.6-0.90.60.50.8-0.8-0.9-1.0-0.90.7-0.91.0-1.0-1.01.0-0.81.0-1.01.00.9-1.51.0
BMI with tail1.65.56.4-2.32.42.2-2.22.4-2.3-2.2-2.52.52.52.52.5-2.42.5-2.52.52.5-2.32.2-2.52.4-2.3-2.21.9-1.5
BMI without tail1.36.88.0-2.82.82.6-2.52.7-2.7-2.5-2.82.82.82.72.8-2.72.8-2.62.82.7-2.42.7-2.82.7-2.6-2.32.0-1.3
Body weight2.912.917.6-4.24.04.1-4.13.9-4.1-3.9-3.93.93.93.63.7-4.03.7-3.43.43.4-3.34.1-3.43.4-3.3-2.31.8-0.5
Weight adjusted by age0.00.10.7-0.40.40.6-0.70.4-0.5-0.2-0.30.30.30.30.2-0.60.2-0.20.10.1-0.20.9-0.10.0-0.10.20.10.5
Bone surface0.81.52.1-1.31.41.3-1.41.4-1.2-1.2-1.31.31.31.41.3-1.31.3-1.31.21.2-1.31.0-1.21.4-1.2-1.01.0-0.5
Bone volume0.71.31.8-1.11.21.0-1.11.3-1.0-1.0-1.21.21.21.31.2-1.01.2-1.31.21.2-1.20.7-1.21.3-1.2-1.21.1-0.9
Breakpoint value in progressive ratio session1.52.610.40.4-1.0-0.40.4-1.1-0.10.21.1-1.2-1.3-1.7-1.50.0-1.62.0-1.9-1.92.00.32.0-2.02.02.6-2.53.2
Number of licking bursts2.16.37.5-2.52.62.3-2.32.6-2.5-2.7-2.62.62.72.62.7-2.32.7-2.52.72.7-2.52.5-2.72.6-2.6-2.32.0-1.6
Context. condit. distance diff. score0.10.10.20.5-0.4-0.40.4-0.30.40.40.4-0.3-0.3-0.2-0.30.3-0.30.2-0.2-0.20.2-0.40.2-0.30.20.0-0.0-0.2
Locomotion velocity, session 11.01.18.2-0.90.41.2-1.20.5-1.1-1.0-0.40.40.2-0.0-0.0-1.2-0.20.3-0.5-0.60.41.70.5-0.50.41.7-2.12.9
Locomotion distance, session 10.30.42.1-0.70.40.9-0.90.4-0.9-0.9-0.50.40.40.10.2-0.80.20.1-0.1-0.1-0.01.2-0.0-0.1-0.00.7-1.01.4
Locomotion velocity, session 22.73.24.1-1.61.91.7-1.71.9-1.5-1.5-1.81.81.82.01.9-1.71.9-2.01.91.9-2.01.2-1.82.0-2.0-1.91.8-1.4
Locomotion distance, session 21.82.54.6-2.01.72.0-1.91.6-2.0-2.1-1.81.81.71.31.6-1.81.5-1.21.41.3-1.32.1-1.41.3-1.3-0.60.20.4
Locomotion velocity, session 30.20.32.0-0.40.00.4-0.40.0-0.5-0.4-0.10.0-0.0-0.2-0.1-0.4-0.20.4-0.4-0.40.30.80.3-0.30.30.9-1.11.4
Locomotion distance, session 31.82.04.2-1.81.61.8-1.81.5-1.8-1.8-1.61.51.51.31.4-1.71.3-1.11.21.1-1.22.1-1.31.2-1.2-0.50.10.4
Stereotopy head waving bouts, day 30.40.52.50.2-0.4-0.10.1-0.30.10.10.4-0.4-0.5-0.5-0.6-0.0-0.70.7-0.8-0.90.80.30.8-0.80.81.3-1.31.6
Stereotopy head waving duration, day 30.40.51.00.5-0.6-0.50.5-0.60.50.50.7-0.7-0.7-0.6-0.80.3-0.80.7-0.9-0.90.8-0.30.9-0.90.81.0-0.91.0
Locomotion velocity, session 70.10.10.20.3-0.4-0.30.3-0.30.30.20.3-0.3-0.3-0.4-0.30.3-0.30.4-0.3-0.30.3-0.20.3-0.30.30.3-0.30.1
Locomotion distance, session 70.20.20.6-0.60.40.6-0.50.4-0.6-0.8-0.50.50.50.30.4-0.60.4-0.30.30.3-0.20.7-0.30.3-0.20.1-0.20.4
Stereotopy head waving bouts, day 70.91.11.9-1.21.21.3-1.31.2-1.3-1.1-1.11.11.11.11.0-1.41.0-1.00.90.8-0.91.4-0.90.9-0.9-0.40.20.3
Stereotopy head waving duration, day 70.50.61.0-0.90.90.9-0.90.9-0.9-0.8-0.80.80.80.90.7-1.00.7-0.80.60.6-0.61.0-0.60.7-0.6-0.30.20.2
Locomotion velocity, session 80.10.21.2-0.30.00.2-0.2-0.1-0.3-0.3-0.0-0.0-0.1-0.2-0.1-0.3-0.20.4-0.3-0.30.30.50.3-0.20.30.8-0.81.1
Locomotion distance, session 80.20.20.8-0.60.40.7-0.60.4-0.7-0.8-0.50.40.40.20.3-0.70.2-0.00.10.1-0.10.9-0.10.1-0.10.4-0.60.9
Degree of sensitization distance0.91.01.51.2-1.2-1.21.2-1.11.21.01.1-1.1-1.1-1.0-1.01.0-1.00.9-1.0-0.91.0-1.21.0-0.91.00.6-0.50.1
Degree of sensitization stereotypy1.21.31.7-1.21.31.2-1.21.3-1.3-1.1-1.21.21.21.21.2-1.21.2-1.21.11.1-1.11.2-1.21.2-1.1-0.90.7-0.4
Conditioned locomotion0.20.31.30.1-0.3-0.10.1-0.3-0.2-0.20.2-0.2-0.3-0.5-0.4-0.1-0.40.6-0.5-0.60.60.40.4-0.60.60.8-1.11.1
Cocaine response after cond. corrected2.03.05.21.3-1.6-1.41.4-1.71.11.01.5-1.6-1.7-1.8-1.81.3-1.81.9-2.0-2.02.0-0.71.9-1.82.02.2-2.32.2
Cocaine response after cond. not corrected1.72.55.21.1-1.4-1.11.2-1.40.90.81.4-1.4-1.5-1.6-1.61.1-1.71.7-1.8-1.91.9-0.51.8-1.71.92.2-2.22.3
Cocaine response before conditioning0.81.01.2-1.11.00.9-1.01.1-1.0-1.0-1.01.01.01.01.1-0.91.0-1.01.01.0-1.00.9-1.11.1-1.0-0.80.9-0.6
Saline control response0.60.82.2-1.21.01.3-1.20.9-1.3-1.4-1.00.90.90.60.8-1.00.7-0.50.50.5-0.51.5-0.60.6-0.60.2-0.40.9
Bone: connectivity density0.81.42.3-0.91.10.9-1.01.2-0.7-0.6-1.01.11.11.31.2-1.11.2-1.41.31.3-1.40.2-1.21.3-1.3-1.51.5-1.3
Bone: cortical apparent density0.20.32.10.20.1-0.30.40.10.20.1-0.10.10.20.50.30.20.4-0.60.50.6-0.4-0.4-0.60.4-0.5-1.11.1-1.5
Bone: cortical area2.94.76.6-2.02.21.6-1.72.0-2.0-1.9-2.22.22.32.02.4-1.62.4-2.12.52.5-2.31.6-2.52.5-2.2-2.62.3-2.2
Bone: cortical porosity0.20.20.60.5-0.4-0.40.4-0.40.60.60.5-0.5-0.5-0.4-0.40.2-0.40.4-0.4-0.40.3-0.80.5-0.30.40.2-0.2-0.0
Bone: cortical porosity0.00.00.10.00.00.1-0.10.00.10.10.0-0.0-0.00.0-0.1-0.2-0.10.0-0.1-0.1-0.0-0.20.10.0-0.00.1-0.10.1
Bone: cortical thickness1.22.05.3-1.01.10.5-0.51.1-1.0-0.9-1.31.31.41.21.5-0.51.6-1.41.71.8-1.50.5-1.81.6-1.4-2.22.0-2.3
Bone: cortical thickness0.20.20.70.5-0.5-0.90.8-0.50.50.60.4-0.4-0.3-0.5-0.20.7-0.20.4-0.1-0.10.3-0.6-0.0-0.20.3-0.20.5-0.8
Bone: cortical tissue density0.10.21.60.3-0.0-0.30.50.00.20.2-0.00.00.10.40.20.20.3-0.50.40.4-0.2-0.5-0.50.3-0.3-0.91.0-1.3
Condit. Reinf. active minus inactive responses0.70.71.0-0.70.80.8-0.81.0-0.8-0.7-0.80.90.91.00.9-0.90.9-1.00.90.9-1.00.7-0.90.9-1.0-0.90.8-0.7
Condit. Reinf. active-inactive response ratio0.50.60.90.9-0.9-0.91.0-0.80.91.00.8-0.8-0.8-0.7-0.80.9-0.70.6-0.7-0.70.7-0.90.7-0.80.70.4-0.2-0.1
Condit. Reinf. active responses3.34.35.4-1.92.12.0-2.02.3-1.9-1.8-2.12.12.12.32.1-2.12.2-2.32.22.2-2.31.7-2.22.1-2.3-2.01.8-1.4
Condit. Reinf. inactive responses4.05.26.4-2.12.42.1-2.22.4-2.0-1.9-2.32.32.42.52.4-2.22.4-2.52.52.5-2.51.7-2.42.4-2.5-2.42.2-1.8
Incentive salience index mean4.55.87.2-2.42.52.6-2.62.7-2.5-2.4-2.52.52.52.62.5-2.72.5-2.52.42.4-2.52.3-2.42.4-2.5-1.91.6-1.0
Condit. Reinf. lever presses9.514.319.5-4.14.14.3-4.34.2-4.1-4.1-4.14.14.04.03.9-4.43.8-3.83.63.6-3.74.1-3.63.6-3.7-2.61.9-0.7
Condit. Reinf. active minus inactive responses0.61.01.2-1.01.00.9-0.90.9-0.9-1.0-1.01.01.01.01.0-0.71.1-1.01.11.1-1.00.8-1.11.0-1.1-1.10.9-0.8
Condit. Reinf. active-inactive response ratio0.10.20.5-0.30.40.3-0.20.3-0.2-0.3-0.30.30.40.40.4-0.10.4-0.50.50.5-0.5-0.0-0.40.5-0.5-0.70.7-0.7
Condit. Reinf. active responses2.33.33.9-2.01.91.9-1.91.9-1.9-1.9-1.91.91.91.81.9-1.71.9-1.81.91.9-1.91.8-1.91.7-1.9-1.71.3-0.9
Condit. Reinf. inactive responses2.74.15.1-2.02.01.9-2.02.1-2.0-2.0-2.12.12.12.12.2-1.92.2-2.12.22.2-2.11.8-2.31.9-2.1-2.01.7-1.4
Condit. Reinf. lever presses3.24.76.6-1.92.11.8-1.82.2-1.7-1.8-2.12.12.22.32.3-1.72.4-2.42.42.4-2.41.4-2.42.2-2.4-2.62.3-2.1
Condit. Reinf. lever reinforcers received2.83.94.6-2.12.12.0-2.12.1-2.0-2.0-2.12.12.12.12.1-1.92.1-2.02.02.0-2.11.9-2.11.9-2.1-1.81.4-1.1
Conditioned reinforcement - actives0.00.10.4-0.0-0.00.1-0.1-0.20.2-0.60.1-0.1-0.1-0.1-0.2-0.1-0.20.2-0.3-0.30.3-0.50.4-0.30.30.3-0.50.5
Conditioned reinforcement - inactives0.30.71.70.6-0.8-0.70.7-0.90.7-0.00.7-0.7-0.8-1.0-0.80.1-0.81.0-0.9-0.91.0-0.60.8-1.01.00.9-1.30.9
Conditioned locomotion0.10.21.5-0.2-0.00.3-0.3-0.0-0.1-0.70.0-0.0-0.1-0.2-0.2-0.0-0.20.3-0.3-0.30.30.10.3-0.30.30.7-1.21.0
Patch foraging indifference point 0 sec0.30.75.0-0.70.21.0-0.90.2-0.7-0.8-0.30.20.1-0.1-0.1-1.3-0.20.4-0.5-0.50.41.20.4-0.50.51.2-1.92.2
Patch foraging indifference point AUC4.711.114.9-3.83.83.9-3.83.7-3.5-3.4-3.53.53.53.63.4-3.63.3-3.43.33.2-3.43.2-3.03.3-3.4-2.42.2-1.0
Delay disc. indifference point, 0s delay1.21.31.81.0-1.1-0.80.8-1.10.90.81.2-1.2-1.2-1.2-1.30.7-1.31.3-1.3-1.41.3-0.91.3-1.41.31.3-1.31.3
Delay disc. indifference point, 16s delay1.41.95.20.9-1.3-0.80.8-1.30.50.71.2-1.2-1.3-1.5-1.40.8-1.41.6-1.6-1.61.6-0.61.5-1.71.61.8-2.31.9
Delay disc. indifference point, 2s delay0.10.10.4-0.00.10.1-0.10.2-0.0-0.2-0.20.20.20.30.3-0.20.3-0.40.40.4-0.4-0.2-0.40.4-0.4-0.60.2-0.6
Delay disc. indifference point, 24s delay0.10.10.20.4-0.4-0.40.4-0.30.10.40.3-0.3-0.3-0.3-0.30.1-0.30.3-0.3-0.30.3-0.30.2-0.30.30.1-0.20.0
Delay disc. indifference point, 4s delay0.10.10.90.3-0.4-0.20.2-0.30.30.10.3-0.3-0.3-0.3-0.30.9-0.30.3-0.3-0.30.3-0.40.3-0.30.30.3-0.80.3
Delay disc. indifference point, 8s delay0.00.00.1-0.10.10.1-0.10.1-0.0-0.1-0.10.10.10.10.1-0.20.2-0.10.10.1-0.1-0.1-0.10.2-0.1-0.4-0.2-0.0
Indifference point function ln k1.44.25.52.3-2.3-2.32.3-2.32.01.92.2-2.2-2.2-2.3-2.11.9-2.12.2-2.1-2.12.2-1.81.9-2.12.21.7-1.60.9
Indifference point function log k1.44.25.52.3-2.3-2.32.3-2.32.01.92.2-2.2-2.2-2.3-2.11.9-2.12.2-2.1-2.12.2-1.81.9-2.12.21.7-1.60.9
Patch foraging total patch changes 0 sec0.30.83.7-1.10.71.3-1.30.6-1.1-1.2-0.70.60.50.30.4-1.70.3-0.0-0.0-0.1-0.01.5-0.0-0.00.00.8-1.51.9
Patch foraging total patch changes 12 sec2.02.63.6-1.81.81.9-1.81.7-1.7-1.7-1.71.71.71.71.7-1.91.6-1.61.61.6-1.71.5-1.51.6-1.6-1.21.1-0.6
Patch foraging total patch changes 18 sec0.40.91.7-1.31.11.3-1.31.0-1.1-1.1-1.01.01.01.00.9-1.20.9-0.90.80.8-0.91.2-0.70.8-0.9-0.50.30.1
Patch foraging total patch changes 24 sec0.82.84.8-2.12.02.2-2.11.8-1.8-1.8-1.81.81.71.71.6-2.01.6-1.61.51.4-1.61.6-1.41.6-1.6-0.80.70.1
Patch foraging total patch changes 6 sec1.83.06.5-2.31.92.3-2.31.8-2.2-2.1-1.91.91.81.71.6-2.51.6-1.41.31.3-1.32.3-1.21.4-1.3-0.5-0.10.8
Patch foraging time to switch 0 sec1.03.76.22.4-2.2-2.52.5-2.22.12.12.1-2.1-2.0-2.1-1.92.4-1.81.9-1.7-1.71.9-2.11.6-1.71.81.0-0.8-0.1
Patch foraging water rate 0 sec0.52.03.6-1.81.61.9-1.91.5-1.7-1.7-1.51.51.51.41.4-1.81.3-1.21.11.1-1.21.8-1.11.0-1.1-0.40.10.6
Patch foraging water rate 12 sec0.00.10.4-0.2-0.00.00.0-0.1-0.2-0.20.0-0.0-0.1-0.2-0.10.2-0.10.2-0.2-0.20.30.20.1-0.10.30.4-0.60.6
Patch foraging water rate 18 sec0.20.40.9-0.60.60.5-0.40.5-0.5-0.5-0.60.60.70.60.7-0.40.7-0.60.80.8-0.70.2-0.90.8-0.7-0.90.9-0.9
Patch foraging water rate 24 sec0.10.21.40.3-0.1-0.30.4-0.10.40.50.1-0.1-0.00.10.10.20.1-0.30.30.3-0.3-0.9-0.30.3-0.2-0.71.1-1.2
Patch foraging water rate 6 sec0.50.81.7-1.01.00.9-0.90.9-1.0-1.3-1.01.01.00.81.0-0.60.9-0.70.90.9-0.81.1-1.10.9-0.8-0.40.5-0.2
Seeking ratio, delayed vs. immediate footshock2.84.05.3-1.92.01.9-1.92.1-2.3-2.2-2.22.22.22.02.2-1.52.2-2.02.12.1-1.91.9-2.31.9-1.9-2.21.4-1.1
Distance traveled before self-admin1.84.09.6-2.42.22.4-2.42.2-3.1-2.9-2.22.22.11.82.1-1.42.0-1.51.81.8-1.62.8-1.91.6-1.6-0.70.30.2
Distance traveled after self-admin1.11.93.6-1.11.21.0-1.01.3-1.5-1.8-1.51.41.51.41.5-0.71.6-1.41.61.6-1.41.4-1.91.4-1.4-1.30.9-1.3
Extensor digitorum longus weight4.819.024.5-4.84.74.8-4.64.6-4.9-4.7-4.74.74.74.44.6-4.94.5-4.24.44.3-4.24.5-4.34.2-4.3-3.42.6-1.5
Bone: elastic displacement4.75.98.62.8-2.7-2.82.9-2.72.92.92.7-2.6-2.6-2.5-2.52.8-2.42.3-2.2-2.22.3-2.82.2-2.22.21.4-0.8-0.0
Bone: elastic work1.72.25.51.9-1.6-2.12.2-1.62.02.11.5-1.5-1.4-1.2-1.22.1-1.00.9-0.7-0.70.9-2.30.8-0.90.9-0.50.9-1.8
Bone: endosteal estimation1.02.54.0-1.91.92.0-2.01.8-1.9-1.8-1.71.71.61.51.5-1.81.4-1.41.31.3-1.41.9-1.31.6-1.4-0.60.70.2
Bone: endosteal perimeter0.92.24.2-1.91.71.9-1.91.6-1.9-1.8-1.61.61.61.31.5-1.81.4-1.21.21.2-1.22.0-1.21.4-1.2-0.50.30.5
Epididymis fat weight0.31.62.1-1.11.31.2-1.11.3-1.1-1.0-1.31.31.31.41.3-1.21.3-1.41.41.4-1.41.0-1.31.4-1.4-1.41.3-1.0
Delta time in closed arm before/after self-admin0.90.92.8-0.50.70.2-0.20.7-0.6-0.2-0.80.80.80.90.90.11.0-1.01.11.1-1.00.5-1.21.0-1.0-1.51.7-1.5
Delta time in open arm before/after self-admin0.50.51.80.5-0.7-0.30.3-0.70.50.30.6-0.6-0.7-0.8-0.7-0.0-0.80.9-0.8-0.90.8-0.50.9-0.80.80.7-1.31.1
Diff in mean of infusions in LGA sessions0.10.10.60.4-0.2-0.50.5-0.20.30.40.2-0.2-0.1-0.0-0.10.1-0.0-0.10.10.1-0.0-0.3-0.00.1-0.0-0.40.7-0.7
Delay discount exponential model param0.50.72.3-0.70.80.5-0.50.8-0.5-0.4-0.70.70.80.90.8-0.60.8-0.90.90.9-0.90.7-0.90.9-0.9-0.81.5-1.0
Extinction: sum of active levers before priming2.84.35.32.1-2.3-2.02.0-2.21.51.72.1-2.1-2.1-2.3-2.21.3-2.12.3-2.2-2.22.3-1.52.3-2.32.31.8-2.31.5
Active lever presses in extinction session 60.40.40.50.6-0.7-0.60.6-0.70.20.60.7-0.7-0.7-0.7-0.70.5-0.70.7-0.7-0.70.7-0.40.7-0.60.70.6-0.50.5
Bone: final force1.93.13.7-1.91.91.6-1.61.8-1.8-1.8-1.91.91.91.61.9-1.51.9-1.61.91.9-1.81.6-1.91.9-1.8-1.61.5-1.1
Bone: final moment1.72.73.3-1.71.81.4-1.41.6-1.6-1.6-1.71.71.71.51.8-1.21.8-1.61.81.8-1.71.3-1.81.8-1.7-1.71.6-1.3
Food consumed during 24 hour testing period0.50.92.2-1.21.01.0-1.01.0-1.2-1.3-1.11.11.00.81.0-1.01.0-0.80.90.9-0.81.5-1.00.9-0.8-0.50.20.1
Glucose2.54.05.3-2.32.22.2-2.22.1-2.1-2.0-2.22.22.12.12.1-2.32.1-2.02.02.0-2.02.1-1.91.9-2.0-1.51.2-0.6
Heart weight0.71.11.7-1.21.11.0-1.01.1-1.3-0.8-1.11.11.11.11.1-1.01.2-1.11.11.1-1.00.9-0.91.2-1.0-1.10.8-0.5
Delay discount hyperbolic model param0.30.41.9-0.50.60.4-0.40.6-0.4-0.3-0.60.60.60.70.6-0.50.7-0.80.70.7-0.80.5-0.70.7-0.8-0.71.4-0.9
Intermittent access intake day 1-15 change0.21.22.0-0.81.10.9-0.91.1-1.0-0.8-1.11.11.11.21.2-0.61.2-1.21.21.2-1.21.0-1.41.2-1.2-1.21.3-1.0
Intermittent access intake escalation0.21.12.0-0.71.00.7-0.71.0-0.9-0.7-1.01.01.01.11.1-0.41.1-1.21.21.2-1.21.0-1.31.2-1.2-1.21.4-1.1
Intermittent access intake escalation 21.11.83.9-0.81.10.7-0.71.2-0.9-1.0-1.21.21.31.41.4-0.41.5-1.51.61.6-1.50.9-1.81.5-1.5-1.82.0-1.9
Intermitt. access day 1 inactive lever presses0.11.63.9-1.41.31.4-1.41.3-1.6-1.3-1.41.41.31.11.3-2.01.3-1.01.21.2-1.11.8-1.21.0-1.1-0.80.4-0.1
Intermitt. access day 15 inactive lever presses0.00.11.1-0.10.10.1-0.10.1-0.5-0.4-0.30.20.2-0.10.20.10.30.10.10.10.11.0-0.4-0.10.1-0.0-0.10.3
Intermitt. access escalation Index0.20.61.6-0.90.91.0-1.00.9-1.1-0.6-0.80.80.80.70.7-1.20.7-0.60.60.6-0.61.3-0.60.6-0.6-0.10.20.2
Intermittent access day 1 total infusions1.13.35.41.4-1.6-1.21.2-1.71.51.01.7-1.7-1.8-1.9-1.90.9-2.02.0-2.1-2.12.1-1.42.3-2.22.12.1-2.22.2
Intermittent access day 15 total infusions0.00.00.00.00.0-0.00.0-0.00.1-0.20.00.0-0.00.0-0.0-0.0-0.0-0.0-0.0-0.00.1-0.10.1-0.10.1-0.10.10.1
Intermittent access terminal intake (last 3 days)0.00.00.5-0.10.10.1-0.10.0-0.1-0.7-0.10.10.10.00.0-0.40.00.0-0.0-0.00.10.10.0-0.10.10.1-0.10.3
Intermittent access total infusions0.10.10.7-0.0-0.00.1-0.1-0.10.2-0.60.1-0.1-0.2-0.2-0.2-0.4-0.30.3-0.4-0.40.4-0.20.5-0.40.40.5-0.60.8
Intermittent access day 1 locomotion1.42.64.71.1-1.5-1.01.0-1.51.41.11.5-1.5-1.6-1.6-1.70.7-1.81.8-1.8-1.81.8-1.32.0-1.91.81.8-2.21.9
Intermittent access day 15 total locomotion0.52.02.71.1-1.3-1.11.1-1.41.41.11.4-1.4-1.4-1.5-1.51.1-1.51.6-1.6-1.61.6-1.11.7-1.61.61.5-1.31.5
Intermittent access total locomotion1.72.13.21.4-1.5-1.41.4-1.51.81.21.5-1.5-1.5-1.5-1.51.3-1.51.4-1.5-1.51.5-1.61.7-1.51.51.1-1.10.8
Intermittent access standard deviation0.00.21.0-0.40.40.4-0.40.4-0.7-1.0-0.60.60.60.40.5-0.30.6-0.30.40.5-0.30.8-0.60.3-0.3-0.4-0.10.0
Left kidney weight0.22.04.7-2.01.71.9-1.81.5-2.0-1.5-1.61.51.51.21.3-1.71.3-0.91.11.0-1.02.2-1.01.1-1.0-0.30.20.7
Right kidney weight0.21.72.7-1.71.51.4-1.51.4-1.5-0.9-1.41.41.41.41.3-1.61.3-1.31.31.3-1.41.4-1.01.3-1.3-1.10.9-0.3
Cocaine induced anxiety0.00.10.20.4-0.4-0.40.4-0.30.5-0.20.3-0.4-0.4-0.3-0.30.5-0.40.3-0.3-0.30.3-0.30.3-0.40.30.4-0.50.1
Post-drug Anxiety0.40.51.8-0.90.81.0-1.00.8-0.7-1.3-0.70.70.70.70.7-0.90.6-0.60.50.5-0.60.6-0.40.6-0.6-0.1-0.10.2
Baseline Anxiety0.60.91.2-1.01.00.9-0.91.0-1.0-0.8-1.01.01.01.01.0-1.11.0-1.01.01.0-1.00.8-1.01.1-1.0-1.00.7-0.6
Tail length1.47.59.9-3.13.13.0-2.92.9-3.0-2.8-2.92.92.92.82.9-2.72.8-2.62.72.7-2.52.9-2.82.8-2.7-1.91.9-0.9
Length with tail1.35.69.9-3.12.83.1-3.02.6-3.1-2.8-2.62.62.52.22.3-2.92.2-1.92.01.9-1.93.0-1.92.0-2.0-0.80.60.7
Length without tail0.10.42.6-0.50.20.6-0.70.2-0.8-0.6-0.10.10.0-0.2-0.1-0.4-0.20.4-0.4-0.40.20.70.4-0.40.31.0-1.21.6
Times rat made contact with spout0.50.50.8-0.50.70.5-0.50.7-0.6-0.6-0.70.70.70.70.8-0.50.8-0.70.80.8-0.70.5-0.90.8-0.7-0.90.9-0.9
Lifetime Intake0.30.42.1-0.1-0.20.1-0.1-0.30.1-0.80.2-0.2-0.3-0.5-0.4-0.2-0.50.6-0.6-0.70.7-0.00.8-0.70.71.0-1.21.5
Liver weight, left0.00.00.2-0.0-0.1-0.10.0-0.1-0.00.10.1-0.1-0.1-0.2-0.2-0.2-0.20.3-0.2-0.20.30.10.3-0.10.30.3-0.30.4
Liver weight, right0.71.32.11.3-1.3-1.31.3-1.41.31.11.2-1.2-1.2-1.2-1.11.5-1.11.2-1.0-1.01.2-1.31.0-1.11.10.6-0.60.1
Locomotor activity0.00.00.3-0.10.00.2-0.10.1-0.1-0.1-0.10.10.10.00.1-0.50.10.00.00.0-0.00.20.00.00.0-0.0-0.10.0
Locomotor testing distance0.20.51.50.3-0.5-0.10.3-0.50.30.10.5-0.5-0.5-0.7-0.6-0.1-0.70.9-0.8-0.80.70.20.8-0.90.91.1-1.21.2
Locomotor testing rearing0.20.92.4-1.11.01.2-1.11.0-1.0-1.5-1.01.01.00.80.9-1.30.9-0.60.80.8-0.71.4-0.90.6-0.6-0.30.10.3
Locomotion in novel chamber0.20.30.80.7-0.6-0.70.7-0.50.90.60.5-0.5-0.5-0.4-0.40.8-0.40.2-0.2-0.20.1-0.90.3-0.20.2-0.3-0.0-0.7
Locomotion in novel chamber post-restriction0.92.67.0-1.21.61.0-1.01.5-0.7-1.0-1.41.51.51.71.6-0.41.7-1.91.91.9-1.90.6-1.61.9-1.9-2.12.6-2.2
Fecal boli incidents, locomotor time 10.30.81.91.3-1.1-1.01.1-1.01.21.41.0-1.0-0.9-0.8-0.90.7-0.80.6-0.7-0.70.7-1.21.0-0.70.60.1-0.2-0.2
Change in fecal boli incidents, locomotor task0.50.61.5-1.10.91.0-1.00.9-1.0-1.2-0.70.70.70.60.6-0.90.5-0.50.40.4-0.41.2-0.50.5-0.50.40.00.6
Time >=10cm from walls, locomotor time 10.20.21.2-0.40.10.4-0.40.0-0.6-0.4-0.10.0-0.0-0.2-0.1-0.4-0.20.4-0.3-0.30.30.60.2-0.30.30.8-1.01.1
Bouts of movement, locomotor time 11.51.92.71.7-1.6-1.51.6-1.41.61.51.5-1.5-1.5-1.3-1.41.3-1.41.2-1.3-1.31.3-1.51.2-1.31.31.0-0.90.3
Total resting periods, locomotor time 12.02.33.61.9-1.7-1.81.9-1.61.91.91.7-1.6-1.6-1.4-1.51.7-1.51.3-1.4-1.31.3-1.81.3-1.31.30.8-0.5-0.1
Rest time, locomotor task time 10.81.23.31.6-1.0-1.61.7-0.91.71.81.0-0.9-0.8-0.5-0.71.5-0.60.1-0.3-0.20.2-1.60.2-0.10.1-0.61.4-1.8
Distance moved, locomotor task time 10.61.73.9-1.81.41.9-2.01.4-2.0-1.9-1.31.31.20.91.0-1.60.9-0.60.70.6-0.71.8-0.60.7-0.60.4-0.71.4
Vertical activity count, locomotor time 10.21.14.1-1.40.91.7-1.70.9-1.4-1.7-0.80.80.70.40.5-1.20.3-0.00.10.0-0.21.40.10.2-0.11.1-1.22.0
Time >=10cm from walls, locomotor time 20.00.10.3-0.30.30.4-0.40.2-0.4-0.4-0.30.30.30.10.2-0.00.2-0.10.20.1-0.10.6-0.10.0-0.1-0.20.00.3
Bouts of movement, locomotor time 20.20.51.0-0.70.60.8-0.80.8-0.6-1.0-0.80.80.80.80.8-0.90.8-0.70.70.7-0.70.6-0.60.6-0.6-0.6-0.3-0.2
Total resting periods, locomotor time 20.00.10.4-0.30.30.4-0.40.4-0.1-0.6-0.40.40.40.40.4-0.70.4-0.40.40.4-0.40.2-0.30.3-0.4-0.4-0.4-0.2
Rest time, locomotor task time 20.50.91.81.1-0.9-1.01.1-0.91.41.31.1-1.0-1.0-0.8-1.01.1-1.00.7-0.8-0.80.6-1.30.8-0.70.60.70.1-0.2
Distance moved, locomotor task time 20.60.91.3-0.70.80.6-0.70.9-0.8-0.7-0.90.91.01.01.0-0.21.0-1.01.11.1-1.00.9-1.11.0-1.0-1.11.1-0.9
Vertical activity count, locomotor time 20.30.61.6-0.90.91.0-1.10.9-1.0-1.1-0.90.90.90.70.8-0.30.8-0.70.70.7-0.71.3-0.60.7-0.6-0.20.50.2
Light reinforcement 10.41.77.5-1.60.81.6-1.50.7-1.9-2.0-1.11.00.80.10.6-1.70.50.30.00.00.12.7-0.3-0.20.11.4-2.12.6
Light reinforcement 20.61.38.8-0.90.41.1-1.10.2-1.1-1.2-0.30.20.0-0.3-0.2-1.3-0.40.7-0.7-0.80.51.50.7-0.50.52.1-2.13.0
Bone: marrow area1.12.84.1-2.02.02.0-2.01.9-1.9-1.8-1.81.81.71.71.7-1.81.6-1.61.51.5-1.61.9-1.41.7-1.6-0.91.0-0.1
Bone: maximum diameter2.75.46.8-2.32.52.1-2.22.4-2.2-2.2-2.42.42.52.32.5-2.12.5-2.32.52.5-2.41.9-2.42.6-2.4-2.32.1-1.6
Bone: maximum force3.36.57.6-2.72.72.4-2.42.6-2.6-2.6-2.72.72.72.52.7-2.32.8-2.52.72.7-2.62.3-2.72.7-2.6-2.42.1-1.6
Bone: maximum moment2.95.56.5-2.42.52.1-2.12.3-2.3-2.2-2.42.42.52.32.5-2.02.5-2.32.52.6-2.52.0-2.52.5-2.5-2.42.2-1.8
Mean time between licks in bursts0.10.40.50.6-0.7-0.70.7-0.70.70.60.7-0.7-0.7-0.7-0.60.7-0.60.7-0.6-0.60.7-0.70.6-0.50.70.5-0.30.1
Mean num. licks in bursts1.02.83.91.8-1.7-1.61.6-1.71.82.01.8-1.8-1.8-1.7-1.81.6-1.81.6-1.7-1.71.6-1.91.8-1.61.61.3-1.00.6
Cd content in liver0.80.91.6-1.21.21.0-1.01.1-1.2-1.3-1.11.11.00.91.0-1.00.9-0.80.90.9-1.01.2-0.91.0-0.7-0.30.6-0.1
Co content in liver0.70.81.90.5-0.8-0.40.4-0.80.50.40.8-0.8-0.8-1.2-0.90.7-1.01.3-1.0-1.01.0-0.21.0-1.00.91.4-1.31.2
Cu content in liver1.61.93.01.6-1.4-1.61.7-1.41.51.61.5-1.5-1.5-1.4-1.41.7-1.41.3-1.3-1.31.4-1.51.2-1.21.31.0-0.50.2
Fe content in liver1.31.62.90.7-1.1-0.90.9-1.30.70.61.1-1.1-1.2-1.6-1.21.1-1.31.7-1.4-1.41.5-0.41.3-1.41.41.7-1.61.5
K content in liver0.40.41.00.3-0.5-0.20.3-0.50.30.30.5-0.5-0.6-0.7-0.60.4-0.70.7-0.7-0.80.8-0.30.8-0.70.61.0-0.91.0
Mg content in liver0.80.81.40.9-1.0-0.70.8-1.01.01.01.0-1.0-1.0-0.9-1.00.8-1.00.9-1.0-1.00.9-1.11.2-0.80.70.8-0.70.6
Mn content in liver1.51.62.4-1.01.30.9-0.91.2-1.0-0.9-1.21.31.31.41.3-0.81.4-1.51.51.5-1.50.8-1.41.5-1.5-1.61.5-1.3
Na content in liver1.31.52.61.3-1.3-1.31.3-1.41.21.21.3-1.3-1.3-1.5-1.21.6-1.21.4-1.2-1.11.3-1.11.1-1.01.11.0-0.60.3
Rb content in liver5.86.89.92.5-2.7-2.62.7-2.92.52.42.7-2.7-2.7-3.1-2.73.1-2.73.0-2.7-2.62.8-2.22.6-2.52.52.4-2.01.4
Se content in liver2.83.35.2-1.61.81.4-1.62.0-1.6-1.6-1.81.91.92.31.9-2.01.9-2.32.02.0-1.91.3-1.91.9-1.7-2.01.7-1.4
Sr content in liver0.60.51.6-0.70.80.6-1.21.0-0.6-0.5-0.60.70.71.10.6-1.30.6-1.00.60.6-1.10.4-0.40.4-0.4-0.60.3-0.0
Zn content in liver0.10.10.4-0.20.40.3-0.30.4-0.2-0.1-0.30.30.30.30.3-0.10.3-0.30.40.4-0.5-0.0-0.40.5-0.6-0.40.6-0.5
Bone: minimum diameter0.00.10.40.10.1-0.20.20.00.20.30.0-0.00.00.10.00.20.1-0.10.20.2-0.1-0.5-0.10.3-0.1-0.40.6-0.6
Time in familiar zone, hab. session 10.60.64.10.9-0.5-1.01.0-0.31.00.90.4-0.4-0.30.1-0.10.80.0-0.30.30.3-0.2-1.4-0.20.2-0.2-1.21.4-2.0
Time in novel zone, hab. session 12.32.66.70.9-1.3-0.80.8-1.40.80.81.3-1.4-1.5-1.8-1.60.9-1.71.9-1.9-1.91.8-0.31.8-1.81.82.5-2.42.6
Total zone transitions, hab. session 10.00.00.0-0.10.10.1-0.10.1-0.1-0.1-0.10.10.10.20.1-0.10.2-0.20.20.2-0.20.0-0.10.2-0.2-0.20.1-0.2
Total locomotion distance, hab. session 10.71.12.7-0.50.80.5-0.50.9-0.4-0.5-0.80.90.91.21.0-0.61.1-1.31.21.2-1.20.0-1.11.1-1.2-1.61.6-1.6
Locomotion velocity, hab. session 12.13.04.3-1.41.71.4-1.41.8-1.3-1.4-1.71.71.82.01.8-1.51.9-2.11.91.9-2.00.9-1.81.9-2.0-2.11.9-1.8
Time in familiar zone, hab. session 20.50.61.71.1-0.8-1.11.1-0.71.11.00.7-0.7-0.6-0.4-0.51.1-0.40.2-0.2-0.20.3-1.30.3-0.40.3-0.50.6-1.2
Time in novel zone, hab. session 21.92.14.50.9-1.2-0.80.9-1.30.80.91.2-1.3-1.3-1.6-1.50.9-1.51.7-1.7-1.71.7-0.41.6-1.61.72.1-2.02.1
Total zone transitions, hab. session 20.50.61.4-1.00.81.1-1.10.8-1.1-1.0-0.80.80.80.60.7-1.00.7-0.50.50.5-0.61.2-0.60.6-0.6-0.0-0.20.6
Total locomotion distance, hab. session 20.91.21.5-1.11.21.2-1.11.2-1.1-1.1-1.11.11.11.21.1-1.21.1-1.21.11.1-1.10.9-1.11.1-1.1-0.90.8-0.5
Locomotion velocity, hab. session 21.21.62.0-1.31.41.4-1.31.4-1.2-1.3-1.31.31.31.41.3-1.41.3-1.41.31.3-1.31.1-1.21.3-1.3-1.11.0-0.7
Novel to familiar place preference ratio3.44.56.01.8-2.1-1.71.7-2.21.71.72.1-2.1-2.2-2.4-2.21.9-2.32.5-2.4-2.42.3-1.32.3-2.32.32.4-2.32.1
Novelty place preference4.55.87.52.2-2.4-2.12.1-2.52.12.12.4-2.4-2.5-2.7-2.52.2-2.62.7-2.6-2.62.6-1.72.6-2.62.62.6-2.42.0
Time in novel zone, NPP test5.87.19.12.4-2.7-2.32.3-2.82.32.32.7-2.7-2.8-3.0-2.82.5-2.93.0-2.9-2.92.8-1.92.8-2.82.82.8-2.62.2
Total zone transitions, NPP test0.60.82.2-1.21.01.3-1.31.0-1.3-1.3-1.01.00.90.70.8-1.20.8-0.60.60.6-0.61.5-0.60.5-0.60.0-0.30.8
Total locomotion distance, NPP test1.72.44.0-1.81.72.0-1.91.7-1.9-1.8-1.71.71.61.61.5-2.01.4-1.41.31.3-1.42.0-1.31.2-1.4-0.60.30.4
Locomotion velocity, NPP test2.33.35.0-2.12.02.2-2.22.0-2.1-2.1-2.02.01.91.91.8-2.21.8-1.81.61.6-1.72.1-1.61.6-1.7-1.00.7-0.0
Intraocular pressure1.93.14.7-2.22.02.2-2.21.8-2.0-2.1-2.01.91.91.71.8-2.11.7-1.61.61.6-1.51.9-1.71.6-1.5-0.80.70.1
Delta distance traveled before/after self-admin0.10.10.40.4-0.3-0.40.4-0.30.40.20.2-0.2-0.1-0.0-0.1-0.2-0.1-0.10.00.0-0.1-0.3-0.20.0-0.1-0.20.2-0.6
Delta ambulatory time before/after self-admin0.30.51.11.0-0.9-1.01.0-0.91.10.80.8-0.8-0.7-0.6-0.60.3-0.60.4-0.5-0.50.5-1.00.3-0.40.50.10.1-0.5
Parametrial fat weight0.20.41.2-0.0-0.3-0.30.3-0.5-0.10.10.3-0.3-0.4-0.7-0.40.6-0.50.8-0.6-0.60.80.50.4-0.80.81.0-1.01.1
Pavlov. Cond. lever latency6.88.611.13.2-3.1-3.23.2-3.23.23.23.1-3.1-3.1-3.2-3.03.3-3.03.0-2.8-2.82.8-3.12.9-2.82.82.1-1.60.8
Pavlov. Cond. magazine entry latency0.70.91.1-0.91.00.9-0.91.0-0.9-0.9-1.01.01.01.01.0-1.01.0-1.01.01.0-0.90.9-1.00.9-0.9-0.80.7-0.5
Pavlov. Cond. change in total contacts2.73.03.9-1.91.92.0-1.91.9-2.0-1.9-1.81.81.81.81.8-1.91.7-1.71.61.6-1.62.0-1.71.6-1.6-1.10.9-0.3
Pavlov. Cond. index score3.64.55.4-2.22.22.2-2.22.3-2.2-2.2-2.22.32.22.32.2-2.32.2-2.32.22.1-2.12.1-2.22.1-2.1-1.81.5-0.9
Pavlov. Cond. latency score3.24.14.9-2.12.22.1-2.12.2-2.1-2.1-2.12.12.12.22.1-2.22.1-2.22.02.0-2.02.0-2.02.0-2.0-1.61.4-0.8
Pavlov. Cond. lever contacts6.47.89.5-3.03.03.0-3.03.0-3.0-2.9-3.03.03.03.02.9-3.12.9-2.92.82.7-2.72.8-2.82.7-2.7-2.11.7-0.9
Pavlov. Cond. magazine entry number0.91.21.51.0-1.1-1.01.0-1.11.01.01.1-1.1-1.1-1.1-1.21.0-1.21.2-1.2-1.21.1-1.01.2-1.01.11.1-1.00.8
Pavlov. Cond. intertrial magazine entries0.30.30.5-0.50.60.6-0.60.7-0.5-0.4-0.60.60.60.70.6-0.60.6-0.70.60.6-0.70.3-0.60.7-0.7-0.60.6-0.4
Pavlov. Cond. lever-magazine prob. diff.3.74.65.6-2.12.22.2-2.12.3-2.1-2.1-2.22.32.32.42.3-2.22.3-2.32.22.2-2.22.0-2.22.1-2.2-1.91.7-1.2
Pavlov. Cond. response bias4.35.46.3-2.42.52.4-2.42.5-2.5-2.4-2.52.52.52.52.4-2.52.4-2.42.32.3-2.32.4-2.42.2-2.3-1.81.5-0.9
Pavlov. Cond. lever latency3.14.35.81.9-2.1-1.81.9-2.21.71.72.0-2.1-2.1-2.3-2.21.7-2.22.3-2.3-2.32.4-1.32.2-2.22.32.4-2.22.0
Pavlov. Cond. magazine entry latency0.10.20.60.6-0.5-0.60.6-0.50.50.50.4-0.4-0.4-0.4-0.40.8-0.30.3-0.2-0.20.2-0.60.2-0.40.3-0.10.1-0.4
Pavlov. Cond. change in total contacts0.92.15.6-0.91.20.7-0.81.2-0.7-0.7-1.21.21.31.51.5-0.51.6-1.71.71.7-1.70.2-1.71.6-1.6-2.22.2-2.4
Pavlov. Cond. index score0.50.82.6-0.50.70.3-0.40.7-0.3-0.3-0.70.70.70.90.9-0.10.9-1.01.01.1-1.10.0-1.00.9-1.0-1.41.5-1.6
Pavlov. Cond. latency score0.61.03.1-0.50.80.4-0.50.8-0.4-0.4-0.80.80.91.01.0-0.21.1-1.21.21.2-1.20.1-1.21.0-1.1-1.61.6-1.8
Pavlov. Cond. lever contacts2.33.44.7-1.61.81.6-1.61.9-1.4-1.4-1.81.81.92.01.9-1.42.0-2.12.12.1-2.11.0-2.01.9-2.0-2.22.0-1.8
Pavlov. Cond. magazine entry number0.40.52.90.2-0.40.00.0-0.40.10.10.4-0.4-0.5-0.6-0.6-0.2-0.70.8-0.9-0.90.80.20.9-0.60.81.3-1.31.7
Pavlov. Cond. intertrial magazine entries0.10.30.5-0.70.60.7-0.70.6-0.6-0.6-0.60.60.60.50.5-0.70.5-0.40.50.5-0.50.6-0.40.6-0.5-0.30.20.1
Pavlov. Cond. lever-magazine prob. diff.0.50.83.0-0.40.70.3-0.30.7-0.3-0.3-0.70.70.80.90.9-0.10.9-1.11.11.1-1.1-0.0-1.10.9-1.0-1.51.6-1.7
Pavlov. Cond. response bias1.31.83.5-1.01.20.9-0.91.3-0.9-0.9-1.21.21.31.41.4-0.71.5-1.51.61.6-1.60.5-1.61.4-1.5-1.91.7-1.8
Time in closed arm before self-admin0.30.50.90.7-0.8-0.70.7-0.71.00.80.7-0.7-0.7-0.6-0.70.8-0.70.6-0.7-0.70.6-0.70.8-0.80.60.5-0.80.2
Time in closed arm after self-admin0.20.31.20.5-0.3-0.80.8-0.30.40.60.3-0.3-0.2-0.1-0.11.1-0.0-0.10.10.1-0.0-0.4-0.3-0.0-0.0-0.51.0-1.1
Time in open arm before self-admin0.91.02.3-1.31.21.4-1.41.1-1.5-1.4-1.11.11.00.90.9-1.50.8-0.70.70.7-0.71.2-0.80.9-0.7-0.10.40.5
Time in open arm after self-admin0.60.72.5-1.10.91.4-1.40.8-1.0-1.1-0.80.80.70.60.6-1.60.6-0.40.40.4-0.50.8-0.20.5-0.5-0.0-0.60.9
Bone: periosteal estimation1.84.35.4-2.32.32.0-2.12.2-2.2-2.1-2.22.22.22.02.2-1.92.2-2.02.22.1-2.12.0-2.12.3-2.0-1.81.7-1.1
Bone: periosteal perimeter0.50.91.8-1.21.11.1-1.11.0-1.3-1.2-1.11.11.10.81.0-1.11.0-0.70.90.9-0.81.3-0.91.0-0.8-0.50.30.0
Bone: post-yield work1.93.25.1-2.12.02.3-2.22.0-2.1-2.1-1.91.91.91.81.8-2.21.7-1.61.61.5-1.72.1-1.51.6-1.6-0.90.60.1
Progressive ratio test 1 active lever presses0.91.64.60.7-0.9-0.60.6-1.00.6-0.11.0-1.0-1.1-1.3-1.20.4-1.31.5-1.5-1.51.6-0.41.4-1.71.61.8-1.92.1
Progressive ratio test 1 breakpoint0.81.34.00.6-0.8-0.50.5-0.90.4-0.20.8-0.9-1.0-1.2-1.10.3-1.11.4-1.3-1.31.5-0.31.2-1.51.51.7-1.82.0
Progressive ratio test 1 inactive lever presses0.30.72.8-1.10.71.2-1.20.6-1.1-1.3-0.70.60.50.20.4-1.30.30.00.00.00.11.60.0-0.10.10.7-1.11.7
Progressive ratio test 2 active lever presses1.52.15.30.8-1.1-0.70.7-1.30.90.01.2-1.2-1.3-1.5-1.40.4-1.51.7-1.7-1.71.8-0.81.8-1.81.82.0-2.12.3
Progressive ratio test 2 breakpoint1.72.25.60.9-1.2-0.70.7-1.31.00.11.2-1.3-1.4-1.5-1.50.5-1.61.7-1.8-1.81.8-0.81.9-1.81.82.0-2.22.4
Progressive ratio test 2 inactive lever presses0.00.10.5-0.30.20.3-0.30.1-0.1-0.7-0.10.10.1-0.00.0-0.6-0.00.1-0.1-0.10.10.10.1-0.10.10.3-0.20.6
Incentive Sensitization - Responses0.30.82.10.6-0.8-0.40.4-0.90.6-0.30.7-0.7-0.8-1.0-0.80.4-0.91.1-1.0-1.01.0-0.40.9-1.01.01.2-1.51.3
Incentive Sensitization - Breakpoint0.40.82.20.6-0.9-0.50.5-0.90.7-0.20.8-0.8-0.8-1.1-0.90.5-0.91.2-1.0-1.01.0-0.41.0-1.01.01.2-1.51.3
Sum of active levers in priming session hrs 5-64.34.06.01.7-2.0-1.61.6-2.01.31.61.9-2.0-2.0-2.2-2.10.9-2.22.3-2.3-2.32.3-1.12.3-2.32.32.3-2.42.1
Progressive ratio0.00.00.2-0.1-0.1-0.00.1-0.1-0.00.20.0-0.0-0.0-0.2-0.1-0.3-0.10.2-0.1-0.10.20.10.2-0.00.20.0-0.40.3
Food seeking constrained by brief footshock5.77.112.5-3.42.93.5-3.43.0-3.2-3.5-2.92.92.82.52.6-3.42.5-2.22.22.2-2.13.4-2.12.1-2.2-1.1-0.20.6
Seeking ratio, punishment vs. effort1.02.34.2-1.71.71.9-1.91.7-1.7-2.1-1.61.61.61.61.5-1.61.5-1.51.41.4-1.41.7-1.41.3-1.4-0.80.5-0.1
Retroperitoneal fat weight0.31.22.61.4-1.3-1.51.6-1.31.41.31.2-1.1-1.1-1.2-1.01.6-1.01.1-0.9-0.81.0-1.20.7-1.01.00.3-0.1-0.4
Reaction time number correct0.00.10.4-0.50.20.5-0.50.2-0.2-0.5-0.20.20.2-0.00.1-0.50.10.1-0.0-0.0-0.00.40.10.1-0.10.2-0.50.7
Reaction time mean minus median0.31.67.3-0.30.70.2-0.30.8-0.50.1-0.80.91.01.01.1-0.51.3-1.31.51.5-1.4-0.2-1.41.4-1.5-2.42.4-2.7
Reaction time mean minus median AUC0.32.25.4-0.91.20.8-0.91.2-0.9-0.4-1.21.31.31.31.5-1.01.6-1.51.71.7-1.70.2-1.61.7-1.8-2.32.3-2.3
Reaction time num false alarms0.10.20.7-0.10.30.2-0.20.30.20.1-0.20.20.30.40.3-0.10.3-0.50.40.4-0.5-0.1-0.50.6-0.6-0.70.8-0.8
Reaction time num false alarms AUC0.20.60.9-0.70.80.8-0.90.8-0.6-0.5-0.80.80.80.70.8-0.70.8-0.70.80.8-0.90.7-0.80.9-0.9-0.80.7-0.4
Reaction time trials correct on left0.00.10.4-0.50.20.5-0.50.2-0.2-0.5-0.20.20.2-0.00.1-0.50.10.1-0.0-0.0-0.00.40.10.1-0.10.2-0.50.7
Reaction time trials on left0.00.10.4-0.40.10.4-0.40.1-0.1-0.4-0.10.10.1-0.10.0-0.4-0.00.2-0.1-0.10.10.30.20.0-0.00.3-0.50.7
Reaction time mean0.51.23.01.5-1.1-1.61.6-1.11.31.71.1-1.0-0.9-0.9-0.71.6-0.60.6-0.4-0.30.5-1.60.3-0.50.4-0.51.1-1.7
Reaction time mean AUC0.61.43.71.7-1.2-1.81.8-1.21.41.91.2-1.1-1.0-0.9-0.81.7-0.70.7-0.5-0.40.6-1.80.4-0.60.5-0.51.1-1.7
Median of all reaction times1.82.85.32.2-1.9-2.22.2-1.81.92.21.8-1.8-1.7-1.7-1.62.3-1.51.5-1.3-1.31.4-2.01.2-1.41.40.60.1-0.7
Reaction time omissions1.32.23.41.7-1.7-1.81.7-1.61.31.81.6-1.6-1.6-1.4-1.61.4-1.51.4-1.5-1.41.5-1.41.5-1.51.51.1-0.80.4
Reaction time false alarm rate0.10.10.40.20.1-0.10.00.10.20.3-0.00.00.00.20.10.20.1-0.30.20.2-0.3-0.2-0.30.3-0.3-0.50.6-0.7
Reaction time premature initiation rate1.82.74.82.2-2.1-2.22.2-1.81.81.91.8-1.8-1.7-1.7-1.62.1-1.51.5-1.4-1.31.5-1.61.2-1.61.50.7-0.6-0.3
Reaction time premature initiations0.62.03.21.7-1.8-1.71.7-1.61.51.51.5-1.5-1.4-1.5-1.41.7-1.31.4-1.3-1.21.4-1.31.2-1.41.30.7-0.80.0
Std. dev. reaction times0.20.75.50.5-0.1-0.60.5-0.00.30.8-0.00.10.20.30.40.30.5-0.50.70.8-0.6-0.9-0.70.6-0.7-1.61.8-2.3
Reaction time trials completed0.00.10.4-0.40.10.4-0.40.1-0.1-0.4-0.10.10.1-0.10.0-0.4-0.00.2-0.1-0.10.10.30.20.0-0.00.3-0.50.7
Reaction time trials AUC0.00.10.4-0.40.10.4-0.40.1-0.1-0.4-0.10.10.1-0.10.0-0.4-0.00.2-0.1-0.10.10.30.20.0-0.00.2-0.50.6
Run reversals in cocaine runway, females0.20.21.0-0.10.30.0-0.10.30.50.4-0.10.10.20.50.2-0.80.2-0.60.40.4-0.6-0.00.00.4-0.5-0.61.0-0.8
Run reversals in cocaine runway, males0.10.10.20.4-0.3-0.30.3-0.30.30.40.3-0.3-0.3-0.3-0.30.4-0.20.3-0.2-0.20.3-0.30.2-0.20.3-0.0-0.00.0
Latency to leave start box in cocaine runway0.60.81.4-0.80.80.7-0.70.9-1.0-0.8-1.00.91.00.91.0-0.51.0-0.91.01.0-0.91.1-1.20.9-0.8-0.90.6-0.7
Latency to leave start box in cocaine runway, F0.10.20.50.3-0.4-0.40.3-0.30.10.20.3-0.3-0.3-0.4-0.30.6-0.30.5-0.4-0.40.50.40.2-0.50.60.5-0.70.6
Latency to leave start box in cocaine runway, M2.42.23.0-1.61.51.6-1.61.6-1.7-1.6-1.61.61.61.61.6-1.41.6-1.51.51.5-1.51.6-1.61.5-1.5-1.10.7-0.6
Std. dev. time between licks in bursts0.20.40.90.6-0.6-0.60.6-0.60.80.70.7-0.7-0.7-0.6-0.60.6-0.60.6-0.6-0.60.6-1.00.7-0.50.60.4-0.20.1
Total sessions with >9 infusions0.50.73.6-0.1-0.30.2-0.2-0.3-0.3-1.00.2-0.3-0.3-0.6-0.5-0.2-0.60.8-0.8-0.80.90.40.8-0.90.91.4-1.91.9
Short access day 1 total inactive lever presses0.30.72.6-1.00.61.0-1.00.6-1.3-1.6-0.70.60.60.20.4-1.10.40.00.10.10.01.6-0.3-0.00.00.8-1.21.4
Short access day 10 total inactive lever presses0.21.11.8-0.90.90.8-0.81.0-1.1-1.2-1.11.11.10.91.1-1.01.2-1.01.11.1-1.01.3-1.31.0-1.0-1.00.6-0.7
Short access day 1 total infusions0.40.74.3-0.3-0.20.3-0.3-0.2-0.6-1.20.1-0.1-0.2-0.6-0.4-0.4-0.50.9-0.7-0.70.90.60.6-0.90.91.5-1.82.1
Short access day 10 total infusions0.50.94.20.0-0.40.0-0.0-0.5-0.1-0.60.4-0.5-0.6-0.8-0.7-0.2-0.81.0-1.0-1.01.10.21.0-1.21.11.6-1.82.1
Short access total infusions1.01.45.90.3-0.7-0.20.2-0.80.2-0.70.7-0.7-0.8-1.1-1.00.2-1.11.4-1.3-1.31.50.01.4-1.51.51.9-2.22.4
Short access day 1 locomotion1.52.56.11.1-1.5-1.11.1-1.50.80.61.4-1.4-1.5-1.8-1.61.0-1.61.9-1.8-1.82.0-0.71.7-2.02.01.9-2.52.0
Short access day 10 total locomotion0.31.11.91.2-1.2-1.21.2-1.11.41.01.1-1.1-1.1-1.0-1.01.3-1.00.9-0.9-0.90.9-1.40.9-1.00.90.4-0.9-0.0
Short access total locomotion0.61.03.60.5-0.9-0.40.4-0.80.40.20.8-0.8-0.9-1.0-0.90.2-1.01.1-1.1-1.11.1-0.51.1-1.21.11.4-1.91.5
One hour access (0.3 mA shock)0.10.21.2-0.60.40.6-0.60.1-0.1-0.4-0.00.1-0.00.1-0.1-0.4-0.20.1-0.3-0.30.1-0.20.6-0.10.10.6-0.31.1
Compulsive drug intake0.40.61.7-0.50.60.4-0.40.6-0.0-0.0-0.60.60.70.70.70.20.8-0.80.90.9-0.9-0.1-0.60.9-0.9-1.31.3-1.2
One hour access (shock baseline)0.20.64.1-0.2-0.10.3-0.3-0.3-0.2-0.50.3-0.3-0.4-0.5-0.6-0.3-0.70.8-0.9-0.90.90.20.9-0.90.91.4-1.32.0
Social response proportion1.41.83.11.7-1.6-1.71.7-1.41.61.61.5-1.5-1.4-1.2-1.31.7-1.31.1-1.1-1.11.2-1.71.1-1.01.10.7-0.1-0.4
Social responses0.81.01.3-1.01.01.1-1.11.1-0.9-1.1-1.11.11.11.11.1-1.11.1-1.11.11.1-1.00.9-1.01.1-1.1-0.80.7-0.5
Social time0.00.00.10.2-0.1-0.20.2-0.10.0-0.00.1-0.2-0.2-0.2-0.2-0.1-0.20.2-0.2-0.20.20.00.1-0.20.20.3-0.20.1
Soleus weight0.30.96.3-0.50.00.5-0.5-0.1-0.8-0.60.1-0.1-0.2-0.6-0.4-0.5-0.60.9-0.8-0.90.91.00.7-0.70.91.8-1.92.5
Bone: stiffness4.37.99.1-2.93.02.7-2.72.9-2.9-2.8-3.03.03.02.83.0-2.63.0-2.83.03.0-2.92.6-3.03.0-2.9-2.52.3-1.6
Tibialis anterior weight7.425.435.3-5.95.65.7-5.55.4-5.9-5.8-5.55.55.44.95.3-5.55.2-4.64.84.8-4.65.8-5.04.8-4.7-3.32.6-0.9
Time to tail flick, vehicle, before self-admin0.50.62.20.7-0.6-0.80.8-0.71.11.30.8-0.7-0.7-0.5-0.71.5-0.70.5-0.5-0.50.5-1.10.6-0.50.50.10.3-0.3
Time to tail flick, vehicle, after self-admin0.10.11.20.00.1-0.00.00.1-0.0-0.1-0.10.20.20.10.21.10.3-0.10.20.3-0.20.1-0.30.2-0.2-0.60.6-0.4
Time to tail flick, test, before self-admin0.40.50.7-0.80.80.8-0.80.7-0.3-0.8-0.60.70.70.80.7-0.90.6-0.80.70.7-0.8-0.0-0.70.9-0.8-0.50.4-0.4
Time to tail flick, test, after self-admin2.93.15.5-1.41.71.2-1.21.7-0.9-1.0-1.61.71.71.91.8-1.41.8-2.02.02.0-2.00.7-1.92.2-2.0-2.32.2-2.1
Delta time to tail flick, vehicle, before/after SA0.20.20.8-0.30.40.4-0.40.4-0.6-0.9-0.50.50.50.40.5-0.40.6-0.40.50.5-0.40.6-0.50.4-0.4-0.50.3-0.2
Delta time to tail flick, test, before/after SA0.10.20.90.2-0.0-0.30.30.10.20.4-0.10.10.10.20.20.40.3-0.30.40.4-0.30.0-0.30.3-0.3-0.80.9-1.0
Tibia length0.10.42.2-0.50.10.4-0.2-0.2-0.5-0.6-0.10.1-0.0-0.6-0.10.1-0.20.8-0.4-0.40.70.90.3-0.30.51.2-1.01.5
Ambulatory time before self-admin1.02.97.5-2.11.92.1-2.11.9-2.7-2.6-1.91.91.81.41.7-1.31.7-1.21.41.4-1.32.4-1.51.3-1.3-0.40.10.4
Ambulatory time after self-admin0.40.61.7-0.80.70.8-0.80.8-1.2-1.3-0.80.80.80.70.8-0.60.8-0.60.70.7-0.71.0-1.00.7-0.7-0.30.2-0.2
Bone: tissue strength0.20.20.3-0.40.50.5-0.40.4-0.4-0.6-0.50.50.50.40.5-0.20.5-0.40.50.5-0.50.5-0.50.5-0.5-0.60.4-0.4
Total heroin consumption2.22.65.81.0-1.5-1.01.0-1.40.60.71.4-1.4-1.5-1.8-1.60.8-1.61.9-1.9-1.92.0-0.21.7-1.92.02.1-2.42.3
Bone: trabecular number1.22.23.1-1.31.51.2-1.31.6-1.1-1.0-1.41.41.51.71.5-1.41.6-1.81.61.6-1.70.5-1.51.7-1.6-1.71.7-1.4
Bone: trabecular spacing0.00.00.30.1-0.0-0.10.2-0.00.0-0.1-0.00.00.1-0.00.10.10.2-0.00.20.2-0.10.1-0.30.1-0.2-0.30.3-0.6
Bone: trabecular thickness0.10.10.90.5-0.3-0.40.4-0.20.60.60.4-0.3-0.3-0.0-0.30.3-0.3-0.1-0.2-0.20.1-1.00.3-0.10.2-0.20.3-0.4
Bone: trabecular tissue density2.64.66.0-2.42.32.3-2.22.3-2.4-2.5-2.32.32.32.22.3-2.22.2-2.12.12.1-2.02.3-2.22.0-2.1-1.51.2-0.7
Water consumed over 24 hours0.51.01.4-1.01.00.9-0.91.0-1.0-1.2-1.11.11.11.01.1-0.81.1-1.01.11.1-1.01.1-1.11.1-1.0-1.00.8-0.7
Number of responses in last shaping day1.31.79.00.0-0.60.1-0.1-0.5-0.5-0.70.5-0.6-0.7-1.1-0.90.2-1.01.4-1.4-1.41.51.01.1-1.51.52.4-2.93.0