Hub : Genes

Atp8b5p

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative polyA XM_039110996.1 0.03 0.02 4.4e-04 0.02 0.02 0.02 0.02 2.7e-03 2.7e-03 5.9e-03 2.3e-03
2 Liver mRNA stability Atp8b5p 0.08 0.05 9.9e-09 0.08 0.07 0.08 0.08 6.6e-09 1.5e-08 4.4e-09 4.0e-09
3 Liver gene expression Atp8b5p 0.34 0.13 0.0e+00 0.28 0.33 0.33 0.33 6.7e-31 4.1e-38 6.1e-38 6.5e-38
4 Adipose mRNA stability Atp8b5p 0.05 0.03 5.6e-06 0.03 0.04 0.04 0.04 3.2e-04 3.1e-05 4.1e-05 8.4e-05
5 Adipose gene expression Atp8b5p 0.17 0.11 0.0e+00 0.13 0.15 0.14 0.14 3.2e-14 5.8e-16 7.3e-16 2.3e-15
6 Brain gene expression Atp8b5p 0.14 0.08 6.6e-13 0.13 0.13 0.14 0.06 2.1e-12 6.8e-12 3.0e-13 4.2e-06
7 Liver alternative polyA XM_039110987.1 0.07 0.04 7.3e-09 0.05 0.07 0.07 0.06 3.8e-06 1.8e-08 7.7e-08 1.8e-07
8 PL gene expression Atp8b5p 0.09 0.06 4.0e-12 0.11 0.11 0.11 0.11 2.9e-12 1.7e-12 1.6e-12 2.6e-12
9 IL gene expression Atp8b5p 0.16 0.11 5.0e-04 0.16 0.16 0.12 0.05 1.1e-04 1.4e-04 9.8e-04 2.4e-02
10 LHb alternative polyA XM_039110996.1 0.14 0.11 5.9e-03 0.1 0.09 0.08 0.1 2.6e-03 4.1e-03 5.1e-03 2.2e-03
11 NAcc gene expression Atp8b5p 0.12 0.07 6.4e-15 0.14 0.13 0.14 0.14 9.3e-16 5.6e-15 1.3e-15 1.2e-15
12 PL alternative polyA XM_039110987.1 0.03 0.02 5.8e-04 0.03 0.03 0.03 0.03 8.9e-04 5.7e-04 5.4e-04 6.0e-04
13 Liver isoform ratio XM_039110998.1 0.04 0.03 6.1e-05 0.04 0.04 0.04 0.04 2.4e-05 3.1e-05 4.0e-05 2.3e-05
14 Liver alternative polyA XM_039110987.1 0.03 0.02 8.6e-05 0.04 0.04 0.03 0.04 2.8e-05 8.7e-05 1.2e-04 4.6e-05
15 pVTA gene expression Atp8b5p 0.13 0.08 6.7e-06 0.14 0.13 0.13 0.04 8.6e-07 3.6e-06 3.0e-06 7.5e-03
16 LHb alternative polyA XM_039110987.1 0.16 0.1 6.7e-04 0.13 0.12 0.11 0.11 5.9e-04 9.7e-04 1.2e-03 1.5e-03
17 Liver intron excision ratio chr5_57583252_57597426 0.04 0.03 3.4e-03 0 0 0.01 0 3.4e-01 2.1e-01 6.3e-02 3.3e-01
18 LHb gene expression Atp8b5p 0.18 0.13 1.3e-03 0.11 0.11 0.04 0.1 1.7e-03 1.5e-03 4.1e-02 2.0e-03
19 Adipose alternative polyA XM_039110996.1 0.02 0.02 6.6e-03 -0 -0 0 -0 4.7e-01 4.1e-01 3.1e-01 7.6e-01
20 Liver intron excision ratio chr5_57533906_57541366 0.02 0.02 9.7e-03 0.01 0.01 0.01 0.01 1.5e-02 1.0e-02 5.1e-02 2.4e-02
21 BLA gene expression Atp8b5p 0.15 0.1 1.6e-07 0.11 0.11 0.11 0.11 2.6e-06 2.8e-06 1.3e-06 2.3e-06
22 Liver intron excision ratio chr5_57549297_57564476 0.09 0.06 3.7e-08 0.03 0.06 0.06 0.06 6.7e-04 2.1e-07 1.5e-07 4.0e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.32.13.6-1.41.51.41.51.5-1.91.5-1.5-1.6-1.5-1.5-1.51.6-1.5-1.5-1.5-0.51.6-1.51.40.90.9
Area under the delay curve0.70.81.40.6-0.7-0.6-0.7-0.80.7-0.80.91.01.01.11.0-1.11.10.60.9-0.3-1.01.2-1.1-0.7-1.0
BMI with tail2.58.110.5-2.93.02.82.92.9-2.83.0-3.1-2.9-3.2-3.2-3.13.2-3.1-3.0-3.0-0.93.1-3.02.72.02.0
BMI without tail5.511.315.1-3.83.83.93.93.8-3.83.8-3.7-3.4-3.7-3.7-3.43.6-3.4-3.3-3.3-2.63.3-3.02.31.40.9
Body weight3.213.317.2-4.14.14.14.14.1-4.04.1-4.0-3.8-4.0-4.0-3.73.9-3.7-3.8-3.6-2.63.7-3.32.71.61.3
Weight adjusted by age0.20.21.5-0.60.40.50.30.3-0.20.2-0.10.10.20.20.0-0.10.00.00.4-1.2-0.30.4-0.7-0.5-1.0
Bone surface0.61.01.7-1.21.21.21.21.2-1.31.1-1.1-1.1-1.0-0.9-0.91.0-0.9-0.9-1.0-1.00.9-0.70.50.0-0.0
Bone volume0.61.11.9-1.21.21.11.21.1-1.41.1-1.1-1.1-1.1-1.0-1.01.1-1.0-0.9-1.1-0.61.0-0.90.80.20.4
Breakpoint value in progressive ratio session1.21.33.90.3-0.5-0.3-0.5-0.60.8-0.70.91.21.21.21.2-1.21.20.91.4-1.2-1.31.6-1.8-1.4-2.0
Number of licking bursts5.05.87.6-2.42.52.52.62.6-2.72.6-2.6-2.5-2.7-2.7-2.52.7-2.5-2.4-2.7-1.02.6-2.52.20.81.4
Context. condit. distance diff. score0.10.10.20.4-0.4-0.4-0.4-0.40.2-0.30.20.30.20.30.2-0.30.20.20.10.5-0.20.10.00.10.2
Locomotion velocity, session 11.41.59.4-1.00.80.90.60.5-0.20.3-0.10.40.30.40.3-0.40.20.40.4-3.1-0.91.4-2.0-2.3-2.9
Locomotion distance, session 10.40.53.4-0.80.60.70.60.5-0.30.4-0.3-0.0-0.1-0.0-0.10.0-0.1-0.0-0.0-1.8-0.20.5-0.9-1.1-1.5
Locomotion velocity, session 22.83.34.7-2.02.01.81.81.9-1.51.8-2.0-1.9-1.8-1.8-2.11.8-2.2-2.0-1.8-0.61.9-1.81.81.61.3
Locomotion distance, session 21.62.24.4-1.91.81.91.91.8-1.81.7-1.6-1.4-1.4-1.4-1.31.4-1.3-1.3-1.4-2.11.1-0.80.3-0.4-0.6
Locomotion velocity, session 30.30.42.1-0.30.20.30.20.10.10.00.10.40.30.30.4-0.30.40.30.3-1.4-0.50.8-1.1-1.3-1.5
Locomotion distance, session 31.61.73.2-1.71.61.71.71.6-1.51.5-1.4-1.2-1.3-1.3-1.21.3-1.1-1.2-1.3-1.81.0-0.80.3-0.2-0.4
Stereotopy head waving bouts, day 30.60.72.40.1-0.2-0.1-0.3-0.30.8-0.50.50.70.70.80.7-0.80.60.80.8-1.1-1.01.2-1.4-1.3-1.6
Stereotopy head waving duration, day 30.60.71.20.5-0.5-0.5-0.7-0.71.0-0.70.70.80.80.90.8-0.90.70.91.0-0.4-1.01.1-1.1-0.9-1.1
Locomotion velocity, session 70.00.10.10.3-0.3-0.3-0.2-0.30.2-0.20.20.30.20.20.3-0.20.30.20.10.2-0.20.2-0.2-0.3-0.1
Locomotion distance, session 70.20.20.5-0.70.70.60.60.5-0.70.5-0.5-0.4-0.3-0.3-0.30.3-0.4-0.3-0.5-0.70.3-0.20.0-0.4-0.2
Stereotopy head waving bouts, day 71.71.93.0-1.61.61.71.71.7-1.31.6-1.5-1.4-1.5-1.5-1.41.5-1.4-1.4-1.3-1.41.2-1.00.70.40.0
Stereotopy head waving duration, day 70.40.41.0-0.80.80.90.90.9-0.40.8-0.7-0.6-0.7-0.7-0.60.7-0.7-0.6-0.5-1.00.5-0.30.1-0.0-0.3
Locomotion velocity, session 80.20.31.3-0.30.20.30.20.1-0.00.00.10.20.20.30.3-0.30.20.30.2-1.1-0.40.6-0.8-1.0-1.2
Locomotion distance, session 80.20.31.5-0.60.60.60.50.5-0.60.4-0.4-0.2-0.2-0.1-0.10.1-0.2-0.1-0.3-1.2-0.00.2-0.5-0.9-0.9
Degree of sensitization distance0.80.81.21.0-0.9-1.1-1.1-1.10.9-1.00.90.91.01.00.8-1.00.81.00.90.9-0.80.7-0.4-0.30.0
Degree of sensitization stereotypy1.01.11.6-1.11.11.31.21.2-1.01.2-1.1-1.1-1.2-1.2-1.11.2-1.1-1.1-1.0-0.81.0-0.90.70.50.3
Conditioned locomotion0.40.51.80.2-0.3-0.2-0.2-0.30.3-0.30.40.60.60.60.6-0.60.60.60.4-1.0-0.70.8-1.1-1.3-1.3
Cocaine response after cond. corrected3.03.45.51.4-1.5-1.2-1.4-1.51.6-1.61.72.01.91.92.0-1.91.92.01.9-0.6-2.12.2-2.3-2.3-2.3
Cocaine response after cond. not corrected2.72.95.91.1-1.3-1.0-1.2-1.31.3-1.41.51.81.81.71.8-1.71.71.91.7-1.0-2.02.1-2.3-2.4-2.4
Cocaine response before conditioning0.91.11.6-1.11.11.01.11.1-1.31.1-1.1-1.0-1.2-1.2-1.01.1-1.1-1.0-1.3-0.41.1-1.10.90.30.6
Saline control response0.60.83.2-1.00.91.21.11.0-1.10.9-0.7-0.6-0.8-0.7-0.40.7-0.4-0.4-0.6-1.80.3-0.0-0.4-1.2-1.1
Bone: connectivity density0.71.11.6-0.91.00.91.01.0-1.31.0-1.1-1.3-1.0-1.0-1.21.1-1.1-1.2-1.1-0.11.2-1.11.11.00.9
Bone: cortical apparent density0.30.52.70.5-0.4-0.4-0.2-0.20.1-0.1-0.1-0.2-0.5-0.4-0.20.4-0.3-0.2-0.41.60.6-0.91.11.01.7
Bone: cortical area2.53.75.1-1.81.91.92.02.0-2.12.0-2.0-2.1-2.3-2.2-2.02.1-1.9-2.0-2.1-0.42.2-2.12.01.11.5
Bone: cortical porosity0.40.40.70.7-0.7-0.7-0.8-0.70.7-0.80.70.50.80.80.6-0.80.60.60.70.5-0.60.6-0.4-0.0-0.2
Bone: cortical porosity0.00.00.00.00.0-0.0-0.1-0.00.1-0.10.1-0.10.20.10.0-0.20.0-0.00.1-0.0-0.10.1-0.00.2-0.1
Bone: cortical thickness1.11.83.3-0.81.00.91.11.1-1.21.2-1.2-1.4-1.6-1.6-1.31.5-1.3-1.3-1.60.61.6-1.81.81.21.8
Bone: cortical thickness0.10.10.80.5-0.5-0.5-0.3-0.40.1-0.30.30.1-0.1-0.00.3-0.00.30.30.00.90.0-0.20.3-0.10.5
Bone: cortical tissue density0.30.42.30.6-0.5-0.5-0.3-0.30.2-0.20.1-0.1-0.3-0.3-0.10.3-0.2-0.1-0.21.50.4-0.71.00.81.5
Condit. Reinf. active minus inactive responses0.60.71.1-0.70.80.80.80.8-0.90.9-0.9-1.0-0.8-0.9-0.90.9-0.9-1.0-1.0-0.10.9-1.00.90.80.7
Condit. Reinf. active-inactive response ratio0.50.51.01.0-1.0-0.9-0.9-0.90.6-0.80.80.60.60.60.7-0.60.80.70.60.9-0.60.4-0.2-0.10.1
Condit. Reinf. active responses3.34.05.0-2.02.12.02.02.1-2.02.1-2.2-2.2-2.1-2.1-2.22.1-2.2-2.2-2.2-0.72.2-2.11.91.61.3
Condit. Reinf. inactive responses4.35.16.4-2.32.32.22.22.3-2.02.3-2.5-2.4-2.4-2.4-2.52.4-2.5-2.5-2.4-0.62.4-2.42.22.01.7
Incentive salience index mean4.35.26.5-2.52.52.52.52.5-2.52.5-2.5-2.5-2.3-2.3-2.52.3-2.4-2.5-2.4-1.62.3-2.11.71.30.8
Condit. Reinf. lever presses9.312.418.5-4.34.24.24.14.1-3.74.0-4.0-3.7-3.4-3.4-3.73.4-3.7-3.8-3.6-3.33.3-2.82.11.40.4
Condit. Reinf. active minus inactive responses0.70.81.2-0.90.91.01.01.0-1.01.0-1.0-1.1-0.9-1.0-1.01.0-1.0-1.0-1.0-0.41.0-0.90.80.40.6
Condit. Reinf. active-inactive response ratio0.20.20.4-0.30.30.40.30.4-0.30.4-0.4-0.6-0.4-0.4-0.50.4-0.5-0.4-0.30.20.5-0.50.60.50.6
Condit. Reinf. active responses2.23.14.2-1.91.91.92.02.0-2.02.0-1.9-1.9-1.8-1.8-1.91.9-1.9-1.8-1.9-1.11.8-1.71.40.70.7
Condit. Reinf. inactive responses3.34.15.7-2.02.11.92.12.1-2.42.2-2.2-2.2-2.1-2.2-2.12.2-2.1-2.2-2.3-0.82.2-2.21.91.21.3
Condit. Reinf. lever presses3.04.15.2-1.91.91.81.92.0-2.02.0-2.1-2.2-2.1-2.1-2.22.1-2.2-2.2-2.1-0.22.3-2.32.21.91.8
Condit. Reinf. lever reinforcers received2.63.74.7-2.12.12.12.12.1-2.22.1-2.1-2.1-1.9-2.0-2.12.0-2.1-2.0-2.0-1.22.0-1.81.50.90.8
Conditioned reinforcement - actives0.20.21.4-0.30.30.20.30.3-0.60.4-0.8-0.4-0.0-0.0-0.40.0-0.4-0.6-1.2-0.30.4-0.10.4-0.50.3
Conditioned reinforcement - inactives0.20.21.10.3-0.4-0.3-0.2-0.30.1-0.30.00.50.50.40.5-0.40.50.2-0.4-0.2-0.30.5-0.4-1.1-0.4
Conditioned locomotion0.30.31.4-0.50.50.40.60.5-0.70.5-0.9-0.4-0.1-0.3-0.40.3-0.4-0.5-1.2-0.60.4-0.20.2-0.8-0.0
Patch foraging indifference point 0 sec0.61.06.6-1.00.70.80.60.5-0.10.3-0.10.30.50.50.3-0.40.30.10.5-2.6-0.71.2-1.6-1.5-2.3
Patch foraging indifference point AUC7.68.813.2-3.63.63.53.43.4-3.13.3-3.2-3.2-2.8-2.9-3.22.9-3.3-3.2-2.8-2.42.9-2.42.01.70.7
Delay disc. indifference point, 0s delay1.61.72.61.0-1.1-1.2-1.2-1.31.2-1.31.41.41.51.51.5-1.51.61.31.40.1-1.51.6-1.4-1.0-1.2
Delay disc. indifference point, 16s delay2.22.24.71.0-1.1-1.0-1.1-1.20.8-1.21.41.61.51.61.6-1.61.61.51.5-0.7-1.71.8-2.0-2.2-1.9
Delay disc. indifference point, 2s delay0.10.10.3-0.00.10.00.10.1-0.20.1-0.2-0.3-0.2-0.2-0.30.2-0.2-0.4-0.30.40.3-0.30.50.60.6
Delay disc. indifference point, 24s delay0.10.10.20.4-0.4-0.3-0.3-0.30.4-0.30.40.30.30.30.4-0.30.40.20.30.3-0.30.3-0.2-0.1-0.1
Delay disc. indifference point, 4s delay0.10.10.20.3-0.3-0.3-0.3-0.30.2-0.30.30.30.30.40.3-0.40.40.10.20.1-0.30.4-0.3-0.2-0.2
Delay disc. indifference point, 8s delay0.00.00.2-0.10.10.10.10.1-0.00.1-0.0-0.0-0.10.00.0-0.00.1-0.4-0.0-0.20.00.1-0.00.5-0.1
Indifference point function ln k2.53.54.72.1-2.1-2.2-2.1-2.11.9-2.12.02.11.91.82.1-1.82.12.01.71.2-1.91.6-1.5-1.2-0.7
Indifference point function log k2.53.54.72.1-2.1-2.2-2.1-2.11.9-2.12.02.11.91.82.1-1.82.12.01.71.2-1.91.6-1.5-1.2-0.7
Patch foraging total patch changes 0 sec0.61.06.9-1.41.11.20.90.9-0.50.7-0.5-0.10.10.1-0.20.0-0.2-0.30.1-2.6-0.30.7-1.2-1.3-2.0
Patch foraging total patch changes 12 sec1.92.53.4-1.81.81.91.81.8-1.71.8-1.7-1.7-1.5-1.6-1.71.6-1.6-1.7-1.5-1.21.6-1.31.10.80.5
Patch foraging total patch changes 18 sec0.60.71.5-1.21.21.21.11.1-0.91.0-0.9-0.8-0.6-0.7-0.80.7-0.9-0.8-0.6-1.20.6-0.40.20.0-0.3
Patch foraging total patch changes 24 sec1.92.34.3-2.12.02.01.91.9-1.81.8-1.7-1.6-1.1-1.3-1.61.3-1.6-1.5-1.3-1.91.2-0.80.60.4-0.3
Patch foraging total patch changes 6 sec1.92.87.5-2.52.32.42.12.1-1.61.9-1.7-1.5-1.1-1.3-1.51.3-1.5-1.7-1.2-2.71.1-0.60.2-0.0-0.9
Patch foraging time to switch 0 sec2.23.56.82.6-2.6-2.4-2.2-2.32.1-2.12.11.91.61.61.9-1.61.91.71.52.3-1.51.1-0.7-0.40.3
Patch foraging water rate 0 sec1.21.94.7-2.01.91.81.71.7-1.61.6-1.4-1.2-1.2-1.2-1.21.1-1.2-1.1-1.0-2.20.9-0.50.1-0.3-0.8
Patch foraging water rate 12 sec0.10.10.6-0.20.10.10.10.1-0.20.0-0.00.2-0.00.10.2-0.10.20.20.0-0.7-0.20.3-0.5-0.8-0.6
Patch foraging water rate 18 sec0.30.40.7-0.50.60.50.60.6-0.90.6-0.6-0.8-0.9-0.8-0.70.7-0.6-0.6-0.60.00.8-0.80.70.50.6
Patch foraging water rate 24 sec0.20.31.40.2-0.0-0.2-0.1-0.0-0.20.1-0.2-0.4-0.5-0.4-0.40.3-0.3-0.2-0.41.10.5-0.70.90.91.2
Patch foraging water rate 6 sec0.60.82.1-0.90.90.91.00.9-1.41.0-1.0-0.9-1.1-1.0-0.81.0-0.7-0.4-1.3-0.80.8-0.80.4-1.00.1
Seeking ratio, delayed vs. immediate footshock3.64.27.3-2.02.02.12.12.1-1.82.2-2.2-1.9-2.3-2.3-1.92.3-2.0-2.7-2.1-0.92.2-2.01.81.91.3
Distance traveled before self-admin3.84.06.6-2.52.42.42.52.3-2.62.3-2.2-1.8-2.1-2.1-1.82.1-1.7-1.7-2.2-2.31.7-1.50.8-0.8-0.1
Distance traveled after self-admin1.01.12.7-0.70.80.81.00.9-1.21.0-1.1-1.1-1.3-1.3-1.01.3-1.0-0.9-1.6-0.11.2-1.31.1-0.10.9
Extensor digitorum longus weight4.216.521.9-4.54.44.74.74.6-4.64.6-4.5-4.3-4.2-4.3-4.14.3-4.1-4.3-4.3-3.04.1-3.62.91.51.3
Bone: elastic displacement3.74.27.32.7-2.6-2.6-2.5-2.52.2-2.42.32.01.91.92.1-2.02.12.01.92.5-1.71.3-0.8-0.10.3
Bone: elastic work1.41.89.32.0-1.8-1.9-1.6-1.61.2-1.41.30.80.70.70.9-0.71.00.80.73.1-0.4-0.10.71.11.8
Bone: endosteal estimation0.81.73.1-1.71.61.81.61.6-1.61.5-1.4-1.2-1.3-1.3-1.21.2-1.1-1.1-1.1-1.81.0-0.70.4-0.3-0.4
Bone: endosteal perimeter0.81.74.2-1.71.61.81.61.6-1.61.5-1.4-1.0-1.2-1.2-1.11.1-1.1-1.1-1.1-2.10.9-0.50.1-0.5-0.8
Epididymis fat weight0.51.11.6-1.31.21.21.21.2-1.21.2-1.1-1.0-1.2-1.1-1.01.0-1.0-0.9-1.0-1.10.9-0.80.5-0.10.0
Delta time in closed arm before/after self-admin3.73.56.1-1.51.61.61.71.8-1.61.8-1.9-2.0-2.0-2.0-2.02.0-2.0-2.3-1.70.12.1-2.12.12.51.8
Delta time in open arm before/after self-admin0.80.81.30.6-0.7-0.6-0.7-0.70.7-0.80.80.91.01.01.0-1.01.00.80.8-0.3-1.01.2-1.1-1.1-1.0
Diff in mean of infusions in LGA sessions0.00.10.50.3-0.2-0.2-0.2-0.20.2-0.20.10.10.10.10.1-0.10.0-0.00.40.4-0.0-0.00.10.70.2
Delay discount exponential model param0.60.61.1-0.50.60.50.60.6-0.60.7-0.8-0.9-0.9-0.9-0.90.9-0.9-0.5-0.80.30.9-1.11.00.61.0
Extinction: sum of active levers before priming1.91.92.71.5-1.6-1.4-1.5-1.51.6-1.51.51.51.51.51.5-1.51.51.21.40.7-1.41.3-1.1-0.4-0.7
Active lever presses in extinction session 60.60.61.40.5-0.6-0.5-0.7-0.61.0-0.80.80.71.11.10.8-1.10.70.61.20.0-0.91.0-0.80.1-0.8
Bone: final force1.21.92.7-1.41.41.51.61.6-1.71.6-1.5-1.5-1.5-1.5-1.41.5-1.2-1.3-1.5-0.81.5-1.31.10.40.6
Bone: final moment0.91.52.1-1.11.21.31.41.3-1.51.4-1.3-1.4-1.4-1.3-1.21.4-1.1-1.2-1.4-0.41.4-1.31.20.50.8
Food consumed during 24 hour testing period0.60.81.3-0.90.91.11.11.1-1.11.1-0.9-0.8-1.0-1.0-0.71.0-0.7-0.8-1.0-1.10.8-0.60.3-0.4-0.2
Glucose1.01.52.1-1.41.41.51.41.4-1.41.4-1.4-1.2-1.4-1.2-1.31.3-1.3-1.3-1.2-1.11.2-1.00.80.60.2
Heart weight0.50.71.3-1.11.01.11.11.1-1.01.0-0.8-0.6-0.9-0.9-0.70.9-0.7-1.0-0.8-1.10.7-0.50.30.2-0.2
Delay discount hyperbolic model param0.50.51.0-0.50.60.50.50.6-0.50.6-0.7-0.8-0.8-0.9-0.80.9-0.9-0.5-0.70.30.8-1.00.90.60.9
Intermittent access intake day 1-15 change1.41.42.6-0.50.70.60.80.8-0.91.0-1.1-1.1-1.4-1.5-1.11.4-1.1-1.2-1.50.61.4-1.61.61.31.6
Intermittent access intake escalation1.81.82.9-0.91.01.01.11.1-1.21.2-1.3-1.4-1.6-1.7-1.41.6-1.4-1.4-1.60.31.5-1.71.61.31.5
Intermittent access intake escalation 22.32.34.2-0.80.90.91.11.1-1.31.3-1.4-1.5-1.8-1.9-1.51.8-1.5-1.5-1.90.71.8-2.02.01.42.0
Intermitt. access day 1 inactive lever presses0.60.60.9-0.90.90.90.90.9-0.90.9-0.8-0.7-0.9-1.0-0.71.0-0.7-0.9-0.7-0.60.8-0.80.50.30.3
Intermitt. access day 15 inactive lever presses0.10.10.4-0.1-0.10.10.20.10.10.10.00.3-0.1-0.30.30.10.3-0.1-0.0-0.6-0.20.1-0.5-0.4-0.5
Intermitt. access escalation Index0.90.81.9-1.21.21.21.11.1-1.21.0-0.8-0.7-1.0-0.9-0.80.9-0.7-0.4-0.5-1.40.6-0.50.0-0.7-0.5
Intermittent access day 1 total infusions1.11.32.70.5-0.7-0.6-0.8-0.81.0-0.90.81.21.51.51.2-1.51.20.81.0-0.8-1.31.7-1.5-1.1-1.6
Intermittent access day 15 total infusions0.30.30.9-0.60.60.60.70.6-0.60.6-0.8-0.5-0.4-0.5-0.50.5-0.5-0.9-0.9-0.50.6-0.40.40.40.2
Intermittent access terminal intake (last 3 days)0.40.51.7-0.70.70.70.80.7-0.90.8-1.0-0.6-0.5-0.5-0.60.5-0.6-0.8-1.3-0.70.6-0.40.4-0.30.1
Intermittent access total infusions0.40.41.1-0.90.80.80.80.7-0.80.7-0.9-0.5-0.3-0.3-0.50.4-0.5-0.9-1.0-1.00.5-0.20.2-0.0-0.2
Intermittent access day 1 locomotion1.61.73.10.8-0.9-0.9-1.1-1.11.4-1.21.21.31.71.71.3-1.71.31.01.5-0.3-1.51.8-1.5-0.5-1.5
Intermittent access day 15 total locomotion0.91.01.51.0-1.1-1.0-1.0-1.01.2-1.00.91.11.21.21.1-1.21.10.70.80.2-1.11.1-1.0-0.6-0.7
Intermittent access total locomotion0.50.51.10.8-0.9-0.8-0.8-0.81.0-0.80.60.80.90.90.8-0.90.80.30.50.6-0.70.7-0.40.2-0.1
Intermittent access standard deviation0.50.51.5-0.40.40.50.60.6-0.60.7-0.8-0.6-0.8-0.9-0.60.8-0.6-0.9-1.20.10.8-0.90.80.50.8
Left kidney weight0.30.82.6-1.31.11.31.21.2-1.01.1-0.8-0.6-0.9-0.9-0.60.9-0.6-0.8-0.5-1.60.5-0.3-0.1-0.3-0.7
Right kidney weight0.00.10.8-0.30.10.30.20.20.00.10.10.2-0.0-0.10.20.00.2-0.00.3-0.9-0.20.3-0.6-0.4-0.8
Cocaine induced anxiety1.21.42.51.3-1.3-1.3-1.2-1.31.0-1.31.11.21.21.21.2-1.21.21.50.90.5-1.21.1-1.0-1.6-0.7
Post-drug Anxiety0.30.40.8-0.70.70.70.70.6-0.90.7-0.6-0.5-0.6-0.6-0.60.6-0.5-0.3-0.7-0.70.5-0.40.2-0.7-0.1
Baseline Anxiety2.12.24.3-1.41.41.41.41.5-1.21.5-1.3-1.6-1.6-1.6-1.71.5-1.6-1.7-1.2-0.21.6-1.61.62.11.2
Tail length2.37.010.5-3.23.13.23.23.1-3.23.1-2.8-2.7-2.8-2.8-2.62.7-2.6-2.5-2.5-2.62.5-2.11.50.70.2
Length with tail0.62.34.8-1.91.92.02.01.9-1.91.8-1.5-1.5-1.4-1.4-1.31.4-1.3-1.4-1.2-2.21.2-0.80.4-0.2-0.6
Length without tail0.51.01.40.9-1.0-1.0-1.0-1.01.2-1.11.11.01.21.11.1-1.11.11.01.10.2-1.11.1-1.0-0.8-0.7
Times rat made contact with spout0.40.50.9-0.20.20.50.60.6-0.70.7-0.6-0.6-0.9-0.9-0.60.9-0.6-0.7-0.80.30.8-1.00.90.41.0
Lifetime Intake0.50.53.0-0.90.70.80.80.7-0.70.6-0.8-0.10.10.0-0.10.0-0.1-0.6-0.8-1.70.10.4-0.5-1.0-1.1
Liver weight, left0.50.71.2-0.90.90.91.00.9-1.11.0-0.8-0.8-1.1-1.0-0.81.0-0.8-0.7-0.9-0.50.9-0.90.60.10.3
Liver weight, right0.10.20.50.3-0.3-0.2-0.2-0.30.3-0.30.30.30.40.40.4-0.40.50.50.3-0.2-0.40.5-0.5-0.7-0.5
Locomotor activity0.00.00.1-0.20.20.10.10.1-0.10.1-0.0-0.0-0.2-0.2-0.10.2-0.1-0.1-0.1-0.10.1-0.10.0-0.10.0
Locomotor testing distance0.20.31.9-0.10.1-0.0-0.1-0.20.1-0.20.30.40.40.40.5-0.40.50.60.3-1.0-0.60.7-0.9-1.4-1.2
Locomotor testing rearing0.60.91.9-1.11.01.11.21.0-1.31.1-1.1-0.8-0.8-0.8-0.80.9-0.6-0.6-1.4-1.30.7-0.50.2-1.2-0.4
Locomotion in novel chamber0.10.21.30.2-0.1-0.1-0.1-0.00.2-0.0-0.0-0.3-0.0-0.0-0.20.0-0.2-0.4-0.10.80.3-0.40.61.10.8
Locomotion in novel chamber post-restriction2.53.15.1-1.31.51.31.41.5-1.61.6-1.7-2.0-1.8-1.7-2.01.6-1.9-1.9-1.90.62.0-2.22.32.02.1
Fecal boli incidents, locomotor time 10.60.72.20.9-0.9-0.9-1.0-0.81.5-0.90.90.60.90.60.6-0.70.50.41.01.0-0.60.5-0.21.00.3
Change in fecal boli incidents, locomotor task0.90.82.7-1.31.31.01.00.9-1.30.9-0.9-0.7-0.7-0.4-0.60.4-0.6-0.1-0.8-1.60.4-0.3-0.2-1.6-0.8
Time >=10cm from walls, locomotor time 10.20.21.0-0.20.10.20.10.0-0.1-0.00.20.30.20.30.3-0.30.30.40.3-0.9-0.40.6-0.8-1.0-1.0
Bouts of movement, locomotor time 11.51.62.41.5-1.5-1.5-1.5-1.51.4-1.51.31.31.31.41.3-1.41.21.41.21.1-1.21.0-0.8-0.4-0.3
Total resting periods, locomotor time 11.71.93.11.8-1.7-1.8-1.7-1.71.6-1.61.41.31.31.41.3-1.41.31.31.31.6-1.20.9-0.60.00.1
Rest time, locomotor task time 11.11.27.31.5-1.2-1.4-1.3-1.11.3-1.00.70.20.50.30.2-0.30.20.50.32.7-0.0-0.61.01.41.9
Distance moved, locomotor task time 11.31.55.6-1.71.61.61.51.4-1.71.3-1.0-0.8-0.9-0.7-0.80.8-0.7-0.7-0.7-2.40.5-0.1-0.4-1.3-1.3
Vertical activity count, locomotor time 11.01.15.9-1.41.21.21.11.0-1.20.8-0.5-0.3-0.4-0.2-0.30.2-0.2-0.1-0.1-2.4-0.00.5-1.0-1.7-1.9
Time >=10cm from walls, locomotor time 20.10.10.3-0.40.30.40.30.4-0.10.3-0.3-0.2-0.2-0.3-0.20.3-0.2-0.5-0.1-0.40.2-0.10.00.3-0.1
Bouts of movement, locomotor time 20.50.60.8-0.90.90.80.80.8-0.80.8-0.9-0.7-0.7-0.7-0.80.7-0.9-0.9-0.8-0.60.8-0.70.60.60.3
Total resting periods, locomotor time 20.20.20.4-0.50.50.50.50.5-0.50.5-0.5-0.4-0.4-0.4-0.50.4-0.6-0.7-0.5-0.30.5-0.40.40.60.3
Rest time, locomotor task time 20.60.71.31.0-0.9-1.1-1.1-1.00.8-1.00.90.61.00.90.6-0.90.61.10.81.0-0.70.4-0.3-0.50.1
Distance moved, locomotor task time 20.70.81.4-0.60.70.70.80.8-0.80.8-0.8-0.9-1.1-1.1-0.91.1-0.8-1.0-0.90.21.0-1.11.01.21.0
Vertical activity count, locomotor time 20.40.40.8-0.80.80.90.80.8-0.70.8-0.6-0.6-0.8-0.9-0.60.9-0.5-0.6-0.5-0.70.6-0.50.20.2-0.1
Light reinforcement 11.01.810.2-1.31.11.51.41.1-1.21.0-0.7-0.1-0.6-0.5-0.10.50.0-0.0-0.6-3.2-0.10.6-1.4-2.9-2.4
Light reinforcement 21.41.910.3-0.90.60.90.60.4-0.40.20.00.40.60.60.5-0.60.50.80.5-3.1-1.01.5-2.1-3.2-3.1
Bone: marrow area0.91.93.2-1.71.71.81.71.7-1.61.6-1.5-1.3-1.4-1.4-1.31.3-1.2-1.2-1.3-1.61.2-0.90.6-0.1-0.2
Bone: maximum diameter2.34.25.5-2.32.32.32.32.3-2.22.3-2.2-2.2-2.2-2.2-2.22.1-2.1-2.1-2.1-1.12.1-1.91.71.01.0
Bone: maximum force2.95.06.3-2.42.52.42.52.5-2.52.5-2.4-2.4-2.4-2.4-2.32.4-2.2-2.3-2.4-1.12.4-2.21.91.01.1
Bone: maximum moment2.34.05.0-2.02.12.12.12.1-2.22.2-2.1-2.2-2.2-2.1-2.12.2-2.0-2.0-2.2-0.72.2-2.11.91.01.3
Mean time between licks in bursts0.30.40.70.9-0.8-0.7-0.7-0.70.7-0.70.70.70.70.60.7-0.60.70.70.60.6-0.60.5-0.3-0.4-0.1
Mean num. licks in bursts2.32.74.22.0-2.1-1.9-1.9-1.91.8-1.81.81.71.71.71.7-1.71.71.61.81.2-1.61.5-1.2-0.2-0.5
Cd content in liver1.01.01.6-0.70.80.91.01.0-1.21.0-1.0-1.1-1.2-1.2-1.01.2-0.9-1.0-1.20.11.2-1.21.30.71.1
Co content in liver1.51.82.61.3-1.3-1.2-1.2-1.31.0-1.31.41.31.41.41.5-1.41.51.61.40.2-1.41.4-1.4-1.5-1.2
Cu content in liver0.60.82.31.2-1.0-1.3-1.1-1.10.8-1.01.00.80.60.60.8-0.60.81.00.61.5-0.60.3-0.1-0.10.5
Fe content in liver0.60.73.4-0.30.20.50.30.2-0.10.10.20.50.50.50.4-0.50.40.50.5-1.8-0.61.0-1.3-1.8-1.9
K content in liver0.50.51.00.4-0.4-0.4-0.5-0.50.4-0.60.70.60.80.80.7-0.80.60.80.8-0.4-0.80.9-0.9-0.9-1.0
Mg content in liver0.60.61.10.6-0.6-0.7-0.8-0.70.9-0.80.80.71.01.00.6-1.00.60.71.00.1-0.90.9-0.8-0.1-0.7
Mn content in liver0.40.51.6-0.30.40.40.40.5-0.20.5-0.5-0.6-0.6-0.6-0.80.6-0.9-0.7-0.60.50.7-0.81.01.31.0
Na content in liver1.21.31.91.2-1.2-1.3-1.2-1.31.1-1.21.31.21.11.11.2-1.11.31.41.10.8-1.10.9-0.8-0.9-0.4
Rb content in liver4.55.57.32.7-2.7-2.5-2.5-2.52.2-2.52.62.42.42.42.6-2.42.62.62.41.2-2.42.3-2.0-1.9-1.4
Se content in liver2.43.04.3-1.71.81.61.61.7-1.41.7-1.8-1.6-1.8-1.8-1.91.8-2.1-2.0-1.8-0.31.9-1.91.81.91.5
Sr content in liver0.70.71.4-1.21.20.80.80.9-0.40.8-0.9-0.6-0.6-0.6-1.00.6-1.1-1.1-0.6-0.40.8-0.70.71.10.4
Zn content in liver0.30.41.1-0.20.30.20.20.3-0.30.3-0.4-0.7-0.5-0.5-0.70.5-0.7-0.5-0.50.70.7-0.80.91.01.0
Bone: minimum diameter0.00.00.20.00.0-0.1-0.1-0.10.1-0.10.00.0-0.00.0-0.1-0.1-0.10.00.10.40.1-0.10.30.40.4
Time in familiar zone, hab. session 10.90.85.10.6-0.3-0.7-0.6-0.40.3-0.30.1-0.3-0.2-0.2-0.30.2-0.4-0.2-0.22.30.6-1.01.41.62.2
Time in novel zone, hab. session 13.43.37.11.2-1.4-1.0-1.2-1.31.4-1.41.61.91.91.81.9-1.82.01.81.8-1.1-2.12.3-2.5-2.3-2.7
Total zone transitions, hab. session 10.00.00.1-0.30.30.10.10.1-0.20.1-0.2-0.2-0.1-0.1-0.20.1-0.3-0.1-0.1-0.00.2-0.20.20.20.1
Total locomotion distance, hab. session 10.91.32.8-0.80.90.60.70.8-0.90.9-1.1-1.2-1.1-1.1-1.31.1-1.3-1.2-1.10.71.3-1.41.61.61.7
Locomotion velocity, hab. session 12.33.24.4-1.71.81.51.61.7-1.71.7-1.9-2.0-1.9-1.8-2.01.8-2.1-2.0-1.80.02.0-2.02.01.91.8
Time in familiar zone, hab. session 20.50.53.20.9-0.7-0.9-0.8-0.70.6-0.60.50.20.20.30.2-0.30.20.30.31.8-0.0-0.30.71.01.3
Time in novel zone, hab. session 22.62.54.61.1-1.3-1.0-1.1-1.21.3-1.31.51.81.61.61.7-1.61.81.71.6-0.8-1.82.0-2.1-2.0-2.2
Total zone transitions, hab. session 20.40.51.8-1.01.01.00.90.9-0.70.8-0.7-0.7-0.6-0.5-0.60.5-0.7-0.5-0.5-1.30.4-0.2-0.1-0.3-0.6
Total locomotion distance, hab. session 20.81.11.6-1.21.21.11.11.1-1.11.1-1.2-1.2-1.1-1.0-1.21.0-1.2-1.1-1.1-0.61.1-1.00.80.60.5
Locomotion velocity, hab. session 21.11.52.1-1.41.41.31.31.3-1.31.3-1.4-1.4-1.3-1.2-1.41.2-1.5-1.3-1.2-0.71.3-1.21.00.80.6
Novel to familiar place preference ratio4.64.76.02.0-2.1-1.8-2.0-2.02.3-2.12.32.32.42.42.4-2.42.52.32.40.0-2.42.5-2.4-1.9-2.1
Novelty place preference5.85.97.42.4-2.5-2.2-2.3-2.42.5-2.52.62.62.62.62.6-2.62.72.62.60.4-2.72.6-2.5-1.9-2.0
Time in novel zone, NPP test7.07.29.02.6-2.7-2.5-2.6-2.72.8-2.72.92.92.92.92.9-2.93.02.82.90.5-2.92.9-2.8-2.2-2.2
Total zone transitions, NPP test0.50.72.7-1.11.01.21.11.0-0.90.9-0.8-0.7-0.7-0.6-0.70.6-0.7-0.6-0.6-1.60.4-0.2-0.2-0.5-0.9
Total locomotion distance, NPP test1.52.03.8-1.91.81.81.71.7-1.51.6-1.6-1.4-1.3-1.2-1.41.2-1.5-1.4-1.3-1.91.1-0.80.4-0.0-0.4
Locomotion velocity, NPP test2.02.94.6-2.12.12.12.02.0-1.81.9-1.9-1.8-1.7-1.6-1.81.6-1.8-1.7-1.6-1.91.5-1.20.80.4-0.1
Intraocular pressure1.72.44.4-2.12.02.01.91.9-1.81.8-1.7-1.5-1.4-1.4-1.51.4-1.6-1.3-1.4-2.01.3-0.90.6-0.2-0.3
Delta distance traveled before/after self-admin0.40.41.01.0-0.9-0.9-0.8-0.80.6-0.80.60.60.50.50.6-0.50.50.80.30.9-0.50.3-0.1-0.50.2
Delta ambulatory time before/after self-admin1.11.32.61.6-1.5-1.5-1.4-1.41.1-1.31.11.01.01.01.0-1.01.01.30.71.4-0.90.7-0.4-0.80.1
Parametrial fat weight0.20.30.7-0.70.70.70.70.6-0.70.6-0.4-0.2-0.7-0.7-0.30.7-0.4-0.2-0.3-0.80.3-0.3-0.0-0.8-0.3
Pavlov. Cond. lever latency6.88.612.33.5-3.5-3.4-3.4-3.33.4-3.33.33.03.03.03.0-3.03.03.13.02.5-2.82.5-1.9-1.1-0.6
Pavlov. Cond. magazine entry latency0.50.70.9-0.90.90.80.80.8-0.80.9-0.9-0.9-0.8-0.8-0.90.8-0.9-0.9-0.9-0.30.9-0.80.80.70.5
Pavlov. Cond. change in total contacts2.42.63.6-1.91.91.81.91.8-1.81.8-1.8-1.7-1.7-1.7-1.61.7-1.6-1.7-1.7-1.41.6-1.41.00.60.3
Pavlov. Cond. index score3.44.35.6-2.32.42.22.32.3-2.22.3-2.3-2.2-2.1-2.1-2.22.1-2.1-2.3-2.2-1.22.1-2.01.71.30.9
Pavlov. Cond. latency score3.03.85.3-2.32.32.12.22.2-2.12.2-2.2-2.1-2.0-2.0-2.12.0-2.0-2.2-2.0-1.22.0-1.81.51.20.8
Pavlov. Cond. lever contacts5.26.08.5-2.92.92.82.82.8-2.72.8-2.7-2.6-2.5-2.5-2.62.5-2.5-2.7-2.5-1.92.4-2.21.71.30.7
Pavlov. Cond. magazine entry number0.91.11.51.1-1.1-1.0-1.1-1.11.1-1.11.21.11.11.21.1-1.21.11.11.20.4-1.11.1-1.0-0.6-0.6
Pavlov. Cond. intertrial magazine entries0.30.40.5-0.60.70.60.60.6-0.60.6-0.6-0.7-0.6-0.6-0.70.6-0.7-0.7-0.6-0.20.6-0.60.60.60.4
Pavlov. Cond. lever-magazine prob. diff.3.34.15.1-2.22.22.12.12.1-2.02.2-2.2-2.2-2.1-2.1-2.22.1-2.1-2.3-2.1-0.92.1-2.01.81.51.2
Pavlov. Cond. response bias3.23.95.1-2.22.32.12.22.2-2.12.2-2.2-2.1-2.0-2.0-2.12.0-2.1-2.1-2.1-1.32.0-1.81.51.00.7
Pavlov. Cond. lever latency3.54.76.11.9-2.0-1.9-2.0-2.12.2-2.22.32.32.32.22.3-2.32.42.42.30.2-2.42.5-2.4-2.1-2.0
Pavlov. Cond. magazine entry latency0.20.30.70.9-0.9-0.7-0.6-0.60.5-0.60.50.40.40.40.5-0.40.50.50.30.8-0.30.3-0.1-0.00.3
Pavlov. Cond. change in total contacts1.62.25.0-0.70.90.81.01.1-1.31.2-1.4-1.5-1.5-1.5-1.51.6-1.6-1.5-1.51.01.8-2.02.12.02.2
Pavlov. Cond. index score0.60.82.1-0.30.40.30.50.5-0.70.6-0.7-0.9-0.8-0.9-0.80.9-0.8-0.9-0.80.81.0-1.21.31.31.4
Pavlov. Cond. latency score0.81.02.7-0.40.50.50.60.7-0.80.8-0.9-1.0-1.0-1.0-1.01.0-1.0-1.0-1.00.81.2-1.41.51.51.6
Pavlov. Cond. lever contacts1.82.43.1-1.51.51.41.51.5-1.61.6-1.7-1.7-1.6-1.6-1.71.6-1.8-1.8-1.6-0.21.7-1.71.71.61.4
Pavlov. Cond. magazine entry number0.40.52.5-0.20.10.1-0.1-0.20.4-0.30.40.50.60.60.5-0.60.50.60.7-1.2-0.81.0-1.2-1.1-1.6
Pavlov. Cond. intertrial magazine entries0.30.40.7-0.80.80.80.80.8-0.50.7-0.7-0.6-0.6-0.5-0.60.6-0.5-0.6-0.5-0.70.5-0.40.2-0.0-0.1
Pavlov. Cond. lever-magazine prob. diff.0.60.82.3-0.20.30.30.50.5-0.70.6-0.7-0.9-0.9-0.9-0.80.9-0.9-0.9-0.80.91.0-1.21.41.41.5
Pavlov. Cond. response bias0.91.21.9-0.80.90.80.90.9-1.11.0-1.1-1.2-1.1-1.1-1.21.1-1.2-1.2-1.20.31.3-1.41.41.31.3
Time in closed arm before self-admin2.52.94.01.8-1.8-1.9-1.9-1.92.0-1.91.81.81.81.81.7-1.81.71.81.71.1-1.81.5-1.3-0.7-0.6
Time in closed arm after self-admin0.10.10.70.4-0.3-0.4-0.3-0.30.4-0.30.10.1-0.0-0.00.00.0-0.00.10.10.80.0-0.30.40.60.6
Time in open arm before self-admin1.81.93.8-1.91.81.81.81.7-1.81.6-1.5-1.3-1.1-1.1-1.21.1-1.2-1.2-1.2-1.91.1-0.70.4-0.5-0.5
Time in open arm after self-admin0.80.82.8-1.41.21.31.21.1-1.11.1-0.9-0.7-0.6-0.6-0.70.6-0.7-0.9-0.6-1.70.5-0.1-0.1-0.5-0.7
Bone: periosteal estimation1.42.94.1-1.91.92.02.02.0-2.01.9-1.8-1.8-1.9-1.9-1.71.8-1.6-1.6-1.8-1.31.7-1.51.20.30.5
Bone: periosteal perimeter0.40.61.7-1.00.91.11.01.0-1.00.9-0.8-0.6-0.8-0.8-0.60.6-0.6-0.6-0.6-1.30.5-0.30.0-0.5-0.5
Bone: post-yield work1.21.63.1-1.81.71.71.61.6-1.31.5-1.4-1.3-1.1-1.1-1.31.1-1.3-1.2-1.1-1.71.0-0.70.40.0-0.4
Progressive ratio test 1 active lever presses0.30.41.8-0.30.20.20.20.1-0.20.1-0.10.40.50.50.4-0.40.40.0-0.1-1.4-0.40.8-0.9-1.2-1.2
Progressive ratio test 1 breakpoint0.30.32.0-0.50.30.40.40.3-0.40.2-0.30.20.30.30.2-0.20.2-0.1-0.3-1.4-0.30.6-0.8-1.1-1.1
Progressive ratio test 1 inactive lever presses0.70.84.6-0.80.50.60.50.4-0.60.3-0.10.30.40.30.3-0.20.30.10.1-2.1-0.50.9-1.3-2.1-1.8
Progressive ratio test 2 active lever presses0.70.73.2-0.0-0.2-0.1-0.2-0.30.2-0.30.20.81.01.00.8-0.90.80.40.1-1.3-0.81.2-1.3-1.8-1.5
Progressive ratio test 2 breakpoint0.80.92.50.2-0.4-0.3-0.4-0.50.5-0.50.41.01.21.21.0-1.11.00.50.3-1.1-1.01.4-1.4-1.6-1.5
Progressive ratio test 2 inactive lever presses0.20.20.9-0.40.30.40.40.3-0.50.4-0.5-0.10.2-0.0-0.10.1-0.1-0.3-0.9-0.80.10.1-0.2-1.0-0.3
Incentive Sensitization - Responses0.30.32.60.2-0.2-0.2-0.1-0.2-0.0-0.20.10.50.40.40.5-0.40.50.3-0.3-0.6-0.40.6-0.7-1.6-0.8
Incentive Sensitization - Breakpoint0.30.32.50.3-0.4-0.3-0.2-0.40.1-0.30.20.60.60.50.6-0.50.60.4-0.1-0.5-0.50.7-0.8-1.6-0.8
Sum of active levers in priming session hrs 5-64.24.05.41.8-1.9-1.8-2.0-2.02.3-2.12.12.22.32.32.2-2.32.11.92.20.3-2.22.2-2.1-1.2-1.7
Progressive ratio0.10.10.20.1-0.2-0.1-0.2-0.10.4-0.20.20.30.30.20.3-0.20.4-0.00.4-0.0-0.20.3-0.30.4-0.3
Food seeking constrained by brief footshock5.16.311.8-3.43.33.33.13.1-3.13.0-2.8-2.2-2.3-2.2-2.32.1-2.3-2.4-2.4-3.32.0-1.50.8-0.5-0.6
Seeking ratio, punishment vs. effort1.61.93.4-1.81.71.61.61.6-1.81.6-1.6-1.4-1.3-1.2-1.41.2-1.4-1.1-1.6-1.51.2-1.00.7-0.7-0.0
Retroperitoneal fat weight0.10.20.60.6-0.6-0.6-0.5-0.50.5-0.40.30.40.10.10.4-0.10.30.30.20.8-0.2-0.00.10.10.5
Reaction time number correct0.10.10.6-0.30.20.40.30.3-0.30.2-0.1-0.0-0.00.10.0-0.10.0-0.1-0.0-0.7-0.10.3-0.4-0.5-0.6
Reaction time mean minus median2.02.611.1-0.40.60.50.70.9-0.71.0-1.2-1.5-1.5-1.4-1.51.6-1.5-1.6-1.21.71.8-2.12.43.32.7
Reaction time mean minus median AUC2.22.89.4-0.91.11.11.21.3-1.21.4-1.5-1.8-1.7-1.5-1.81.6-1.7-1.9-1.50.91.9-2.02.33.12.2
Reaction time num false alarms0.10.21.3-0.10.20.10.10.2-0.00.2-0.1-0.5-0.1-0.3-0.40.3-0.3-0.6-0.20.60.4-0.50.71.10.8
Reaction time num false alarms AUC0.30.40.8-0.70.70.70.70.7-0.60.7-0.6-0.8-0.5-0.7-0.70.7-0.6-0.9-0.6-0.20.7-0.70.60.90.4
Reaction time trials correct on left0.10.10.6-0.30.20.40.30.3-0.30.2-0.1-0.0-0.00.10.0-0.10.0-0.1-0.0-0.7-0.10.3-0.4-0.5-0.6
Reaction time trials on left0.10.10.4-0.20.10.30.20.2-0.20.1-0.00.10.10.20.1-0.20.10.00.1-0.6-0.20.4-0.4-0.5-0.6
Reaction time mean0.81.16.61.5-1.3-1.4-1.2-1.11.0-0.90.80.40.30.40.5-0.30.60.60.42.6-0.1-0.40.81.41.7
Reaction time mean AUC1.01.37.31.6-1.4-1.5-1.3-1.21.1-1.10.90.50.50.50.6-0.50.70.70.62.7-0.2-0.30.81.51.7
Median of all reaction times1.72.45.82.1-2.0-2.1-1.9-1.91.7-1.81.61.41.21.31.4-1.31.61.61.22.4-1.10.6-0.20.10.7
Reaction time omissions1.01.32.21.4-1.4-1.5-1.4-1.41.5-1.41.21.31.01.01.2-1.11.11.21.21.4-1.00.7-0.50.00.1
Reaction time false alarm rate0.10.11.00.00.0-0.1-0.1-0.10.2-0.00.0-0.30.1-0.1-0.20.2-0.1-0.3-0.00.60.2-0.40.51.00.6
Reaction time premature initiation rate1.72.34.82.2-2.1-2.0-1.9-1.81.8-1.71.71.51.01.11.4-1.11.51.51.42.0-1.20.7-0.5-0.00.5
Reaction time premature initiations1.11.63.41.8-1.8-1.6-1.5-1.51.5-1.41.41.30.91.01.3-1.01.31.31.31.4-1.10.7-0.6-0.30.1
Std. dev. reaction times0.91.36.80.5-0.3-0.3-0.1-0.00.00.2-0.4-0.7-0.8-0.7-0.70.8-0.6-0.7-0.62.21.0-1.41.82.62.4
Reaction time trials completed0.10.10.4-0.20.10.30.20.2-0.20.1-0.00.10.10.20.1-0.20.10.00.1-0.6-0.20.4-0.4-0.5-0.6
Reaction time trials AUC0.00.10.4-0.20.10.30.20.2-0.20.1-0.00.00.10.10.1-0.10.1-0.00.1-0.6-0.20.3-0.4-0.4-0.6
Run reversals in cocaine runway, females0.30.31.3-0.20.30.20.10.3-0.10.2-0.2-0.6-0.4-0.4-0.60.3-0.6-0.5-0.10.70.5-0.60.81.10.9
Run reversals in cocaine runway, males0.00.00.30.2-0.2-0.2-0.2-0.20.4-0.20.10.1-0.0-0.00.1-0.20.1-0.10.10.3-0.10.00.10.50.2
Latency to leave start box in cocaine runway0.80.91.3-0.80.80.80.90.9-1.01.0-1.0-0.9-1.1-1.1-0.91.1-0.9-0.9-1.1-0.21.0-1.10.90.50.8
Latency to leave start box in cocaine runway, F0.00.00.00.1-0.2-0.1-0.0-0.10.1-0.10.10.20.10.00.2-0.10.20.20.1-0.1-0.10.0-0.2-0.1-0.2
Latency to leave start box in cocaine runway, M1.21.12.1-1.31.31.31.31.2-1.51.2-1.1-1.0-1.1-1.1-1.01.1-1.0-0.9-1.1-1.20.9-0.80.4-0.5-0.1
Std. dev. time between licks in bursts0.30.40.60.7-0.7-0.7-0.7-0.70.5-0.70.60.60.80.70.6-0.70.60.60.60.5-0.60.5-0.3-0.0-0.1
Total sessions with >9 infusions1.01.14.9-0.1-0.2-0.1-0.1-0.30.2-0.30.31.01.11.11.0-1.01.00.60.3-1.8-1.11.5-1.7-2.2-2.0
Short access day 1 total inactive lever presses1.31.53.3-1.51.41.41.51.4-1.71.4-1.4-0.9-1.1-1.2-0.91.2-0.9-0.9-1.5-1.80.9-0.60.2-1.2-0.5
Short access day 10 total inactive lever presses0.30.30.8-0.40.40.50.60.5-0.70.6-0.6-0.4-0.9-0.9-0.50.8-0.4-0.4-0.7-0.20.6-0.70.4-0.20.3
Short access day 1 total infusions1.01.16.1-1.20.91.01.00.8-1.10.8-0.90.0-0.0-0.0-0.00.10.0-0.3-1.0-2.5-0.10.6-1.0-2.4-1.7
Short access day 10 total infusions0.50.63.6-0.80.60.70.60.5-0.60.4-0.50.10.20.20.1-0.20.1-0.1-0.4-1.9-0.20.7-0.9-1.6-1.4
Short access total infusions0.80.95.8-0.50.30.30.30.1-0.30.1-0.20.60.70.70.6-0.60.60.3-0.3-2.1-0.71.2-1.4-2.4-1.9
Short access day 1 locomotion0.60.61.70.3-0.5-0.4-0.4-0.50.5-0.50.50.90.90.90.9-0.80.90.50.6-0.8-0.91.1-1.2-1.1-1.3
Short access day 10 total locomotion0.50.61.50.9-0.9-0.9-0.9-0.81.2-0.90.60.60.90.80.6-0.80.60.40.61.0-0.60.5-0.10.90.3
Short access total locomotion0.30.31.2-0.20.10.10.10.0-0.1-0.0-0.00.30.50.50.3-0.50.30.20.1-1.1-0.40.7-0.8-0.9-1.1
One hour access (0.3 mA shock)0.30.31.7-0.90.80.80.60.6-0.60.5-0.6-0.40.40.2-0.4-0.2-0.4-0.5-0.3-1.30.10.4-0.3-0.2-0.8
Compulsive drug intake0.30.30.8-0.80.80.70.50.6-0.50.5-0.4-0.7-0.2-0.2-0.70.2-0.7-0.7-0.1-0.40.4-0.20.40.90.1
One hour access (shock baseline)0.20.31.8-0.60.40.50.40.4-0.30.3-0.40.10.30.20.1-0.10.1-0.2-0.3-1.3-0.10.5-0.6-0.7-1.0
Social response proportion1.31.43.21.6-1.5-1.7-1.5-1.51.1-1.41.31.20.81.01.2-1.11.11.30.91.8-0.90.6-0.3-0.40.5
Social responses0.70.91.4-1.11.11.01.01.0-0.91.0-1.0-1.0-1.2-1.0-1.01.0-1.0-1.0-1.0-0.50.9-0.80.80.60.5
Social time0.00.10.20.1-0.1-0.2-0.2-0.20.1-0.20.20.30.10.10.4-0.10.30.40.10.1-0.20.2-0.2-0.5-0.1
Soleus weight0.61.77.20.1-0.30.1-0.1-0.20.3-0.40.61.11.00.91.2-0.91.21.10.9-2.1-1.31.6-2.1-2.7-2.6
Bone: stiffness4.06.38.1-2.72.82.72.82.8-2.92.8-2.7-2.8-2.7-2.6-2.72.7-2.6-2.5-2.7-1.42.6-2.42.11.01.2
Tibialis anterior weight5.920.129.8-5.35.15.45.45.2-5.55.2-5.0-4.6-4.6-4.7-4.44.6-4.4-4.4-4.6-4.24.3-3.62.60.50.6
Time to tail flick, vehicle, before self-admin1.31.32.01.3-1.3-1.3-1.3-1.31.4-1.31.31.21.21.21.1-1.21.11.01.41.0-1.10.9-0.70.4-0.2
Time to tail flick, vehicle, after self-admin0.00.00.10.1-0.2-0.0-0.0-0.10.2-0.00.10.2-0.0-0.00.30.00.3-0.0-0.0-0.2-0.10.1-0.2-0.2-0.2
Time to tail flick, test, before self-admin0.30.30.6-0.50.50.40.50.5-0.60.5-0.6-0.7-0.5-0.5-0.70.5-0.7-0.6-0.80.10.7-0.60.70.40.6
Time to tail flick, test, after self-admin1.01.01.9-0.60.70.70.80.9-0.70.9-1.0-1.2-1.0-1.0-1.11.0-1.1-1.1-1.10.41.2-1.21.41.31.2
Delta time to tail flick, vehicle, before/after SA0.20.20.6-0.50.50.50.60.6-0.50.6-0.6-0.5-0.6-0.6-0.40.6-0.4-0.6-0.8-0.40.5-0.40.3-0.10.1
Delta time to tail flick, test, before/after SA0.10.00.20.3-0.3-0.3-0.2-0.20.3-0.20.20.1-0.0-0.00.20.00.20.20.20.4-0.1-0.00.10.30.2
Tibia length0.30.74.7-0.0-0.10.20.1-0.0-0.3-0.10.40.50.40.40.7-0.40.90.70.4-1.5-0.71.0-1.3-2.2-1.8
Ambulatory time before self-admin2.52.65.7-2.11.92.12.11.9-2.11.9-1.7-1.4-1.5-1.5-1.31.6-1.2-1.4-1.6-2.41.2-0.90.3-0.9-0.6
Ambulatory time after self-admin0.20.20.5-0.40.40.40.50.4-0.70.5-0.5-0.4-0.5-0.5-0.30.5-0.3-0.3-0.7-0.50.4-0.30.2-0.6-0.0
Bone: tissue strength0.20.20.4-0.40.50.40.50.5-0.50.5-0.5-0.6-0.5-0.5-0.50.6-0.4-0.5-0.60.00.6-0.60.60.30.5
Total heroin consumption0.91.12.30.6-0.8-0.6-0.7-0.80.7-0.80.91.11.01.01.2-0.91.21.11.1-0.7-1.21.2-1.5-1.5-1.5
Bone: trabecular number1.52.33.0-1.51.51.41.51.5-1.71.5-1.6-1.7-1.5-1.5-1.71.6-1.7-1.6-1.6-0.21.7-1.61.61.21.3
Bone: trabecular spacing0.10.10.60.1-0.0-0.1-0.1-0.00.10.0-0.1-0.2-0.3-0.3-0.20.2-0.1-0.1-0.20.70.3-0.50.60.40.8
Bone: trabecular thickness0.10.10.20.2-0.1-0.3-0.3-0.30.3-0.30.20.10.40.40.1-0.40.10.10.40.3-0.20.2-0.00.40.1
Bone: trabecular tissue density2.53.54.6-2.12.12.12.12.1-2.12.1-2.0-1.9-2.1-2.0-1.92.0-1.9-1.9-1.9-1.31.9-1.71.40.70.6
Water consumed over 24 hours0.70.81.3-0.70.71.01.01.0-1.11.0-1.0-0.9-1.1-1.1-0.81.1-0.8-0.9-1.1-0.41.0-1.00.80.00.5
Number of responses in last shaping day1.11.28.0-0.50.30.40.30.1-0.30.10.10.70.50.40.7-0.30.70.70.3-2.2-0.81.1-1.7-2.8-2.2