Hub : Genes

Cpsf7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Cpsf7 0.13 0.11 3.6e-03 0.01 0.03 0.03 0.03 7.7e-02 8.0e-03 7.3e-03 9.6e-03
2 Brain intron excision ratio chr1_207183806_207189912 0.02 0.02 8.5e-03 0.01 0.01 -0 0 4.5e-02 3.4e-02 3.8e-01 1.2e-01
3 PL gene expression Cpsf7 0.28 0.13 1.3e-06 0.03 0.05 0.05 0.04 5.5e-04 1.6e-06 5.2e-06 1.5e-05
4 Liver intron excision ratio chr1_207174664_207174926 0.04 0.03 3.9e-03 0.01 0.01 0 0.01 3.0e-02 4.1e-02 1.3e-01 1.6e-02
5 Adipose gene expression Cpsf7 0.13 0.07 4.4e-04 0.02 0.02 0 0.01 3.8e-03 5.5e-03 1.3e-01 1.2e-02
6 Eye alternative TSS XM_006231061.4 0.34 0.15 1.3e-03 0.2 0.12 0.15 -0.02 6.2e-04 6.0e-03 2.8e-03 6.6e-01
7 Eye alternative TSS XM_039085585.1 0.27 0.14 6.8e-03 0.19 0.11 0.16 -0.01 6.8e-04 8.8e-03 2.0e-03 5.4e-01
8 OFC isoform ratio XR_005489751.1 0.26 0.15 1.3e-03 0.07 0.08 0.13 0.12 1.0e-02 6.3e-03 4.8e-04 8.4e-04
9 NAcc isoform ratio XR_005489751.1 0.05 0.03 1.1e-05 0.04 0.03 0.02 0.03 1.4e-05 1.8e-04 7.8e-04 5.4e-04
10 NAcc gene expression Cpsf7 0.18 0.16 3.9e-05 0.04 0.03 0.03 0.03 6.4e-06 2.2e-04 9.3e-05 2.1e-04
11 Liver gene expression Cpsf7 0.11 0.06 1.1e-03 0.01 0.01 0.01 0.01 4.0e-02 4.2e-02 1.7e-02 6.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.20.30.90.7-0.1-0.8-0.50.0-0.80.8-0.90.00.1-0.1
Area under the delay curve0.30.40.90.5-0.4-0.4-0.90.8-0.80.8-1.0-0.2-0.0-0.1
BMI with tail1.54.814.1-0.92.60.70.7-2.8-1.11.1-0.82.7-3.4-3.8
BMI without tail0.81.64.4-1.01.61.60.5-1.30.2-0.20.11.2-2.1-2.0
Body weight1.66.715.9-2.03.22.21.3-3.70.4-0.4-0.73.3-3.5-4.0
Weight adjusted by age3.33.76.2-1.92.51.62.2-2.21.0-1.01.32.3-2.3-2.1
Bone surface0.20.30.50.50.5-0.6-0.3-0.4-0.70.7-0.50.5-0.2-0.5
Bone volume0.30.41.31.0-0.0-1.1-0.5-0.3-0.90.9-0.80.30.3-0.1
Breakpoint value in progressive ratio session3.23.54.8-2.01.91.82.2-1.72.2-2.22.01.5-1.5-1.2
Number of licking bursts0.10.10.50.30.0-0.1-0.2-0.5-0.30.3-0.70.4-0.1-0.4
Context. condit. distance diff. score0.00.00.10.20.10.20.2-0.30.1-0.1-0.20.4-0.2-0.3
Locomotion velocity, session 10.30.30.9-1.00.50.20.50.10.4-0.40.90.1-0.7-0.2
Locomotion distance, session 10.91.23.0-1.71.30.50.9-1.20.5-0.50.01.2-1.5-1.4
Locomotion velocity, session 21.71.93.7-1.71.81.10.9-1.50.7-0.7-0.21.6-1.9-1.9
Locomotion distance, session 21.21.73.5-1.91.31.11.1-1.50.8-0.80.01.4-1.7-1.6
Locomotion velocity, session 30.80.94.20.30.5-0.3-0.9-0.8-0.80.8-2.00.7-0.9-1.3
Locomotion distance, session 30.40.41.50.5-0.6-0.3-1.20.6-0.00.0-1.0-0.70.60.5
Stereotopy head waving bouts, day 30.50.62.2-0.1-0.1-0.5-0.90.0-1.11.1-1.5-0.1-0.8-0.9
Stereotopy head waving duration, day 30.40.41.3-0.20.20.3-0.7-0.2-0.60.6-1.10.1-0.9-1.0
Locomotion velocity, session 70.30.31.50.5-0.4-0.3-1.00.4-0.50.5-1.2-0.30.2-0.1
Locomotion distance, session 70.20.20.90.3-0.40.2-0.70.5-0.30.3-0.9-0.3-0.0-0.2
Stereotopy head waving bouts, day 70.10.20.3-0.10.5-0.10.3-0.5-0.10.10.30.6-0.5-0.6
Stereotopy head waving duration, day 70.60.71.5-0.81.20.70.7-1.00.4-0.40.41.1-1.1-1.1
Locomotion velocity, session 80.20.30.8-0.4-0.10.90.3-0.20.9-0.90.70.10.0-0.0
Locomotion distance, session 80.20.20.6-0.10.2-0.10.0-0.6-0.30.3-0.70.6-0.6-0.8
Degree of sensitization distance0.60.61.8-0.20.5-0.10.6-0.7-0.90.9-0.30.9-1.1-1.3
Degree of sensitization stereotypy0.60.71.4-0.31.10.31.0-1.00.3-0.31.01.2-0.7-0.7
Conditioned locomotion0.40.51.1-1.00.81.10.2-0.00.7-0.70.20.3-1.1-0.8
Cocaine response after cond. corrected0.10.10.5-0.30.20.20.4-0.2-0.20.20.40.3-0.7-0.5
Cocaine response after cond. not corrected0.10.10.3-0.00.0-0.50.50.0-0.50.50.50.1-0.3-0.1
Cocaine response before conditioning0.40.42.00.4-0.1-1.40.50.2-0.20.20.6-0.10.91.0
Saline control response1.82.43.5-1.91.71.51.6-1.61.6-1.61.11.6-1.4-1.3
Bone: connectivity density0.20.30.7-0.20.80.0-0.1-0.3-0.30.3-0.50.6-0.8-0.8
Bone: cortical apparent density0.50.61.2-1.00.70.70.9-0.41.1-1.10.60.6-0.5-0.2
Bone: cortical area0.10.10.5-0.10.2-0.70.3-0.50.0-0.0-0.60.40.1-0.0
Bone: cortical porosity0.40.41.3-0.70.20.90.1-0.01.2-1.20.70.1-0.2-0.0
Bone: cortical porosity0.80.92.2-1.20.61.40.3-0.21.5-1.51.00.3-0.6-0.3
Bone: cortical thickness1.83.05.7-2.41.61.52.0-1.22.4-2.41.11.4-1.2-0.8
Bone: cortical thickness0.40.41.6-0.60.30.90.10.41.3-1.30.2-0.2-0.10.3
Bone: cortical tissue density0.60.81.5-1.10.90.91.0-0.51.2-1.20.70.7-0.6-0.3
Condit. Reinf. active minus inactive responses1.21.42.7-1.71.40.41.5-1.20.7-0.71.11.3-1.3-1.0
Condit. Reinf. active-inactive response ratio1.71.94.0-2.01.30.91.9-0.91.1-1.12.01.0-1.3-0.7
Condit. Reinf. active responses0.91.01.9-1.31.4-0.21.2-1.20.1-0.10.21.3-1.3-1.2
Condit. Reinf. inactive responses0.40.51.90.60.0-1.2-0.2-0.4-0.90.9-1.40.4-0.0-0.3
Incentive salience index mean0.40.51.3-1.11.0-0.30.7-0.70.1-0.1-0.00.9-1.0-0.8
Condit. Reinf. lever presses0.30.31.40.30.0-1.0-0.50.3-0.60.6-1.2-0.10.0-0.0
Condit. Reinf. active minus inactive responses0.20.21.10.10.0-1.00.40.3-0.10.10.7-0.20.20.5
Condit. Reinf. active-inactive response ratio0.30.30.80.80.3-0.80.1-0.5-0.90.9-0.00.5-0.3-0.4
Condit. Reinf. active responses0.10.10.6-0.30.1-0.80.50.20.3-0.30.5-0.10.20.4
Condit. Reinf. inactive responses0.40.51.4-0.4-0.6-0.60.10.90.5-0.50.3-0.81.01.2
Condit. Reinf. lever presses0.40.61.7-0.31.0-0.41.0-1.3-0.10.10.11.3-0.6-0.8
Condit. Reinf. lever reinforcers received0.20.31.0-0.60.6-0.41.0-0.30.6-0.60.90.5-0.10.0
Conditioned reinforcement - actives0.80.82.30.6-1.0-1.2-0.21.3-0.20.20.4-0.91.21.5
Conditioned reinforcement - inactives0.80.92.70.8-0.7-1.7-0.80.7-1.11.1-1.0-0.50.80.6
Conditioned locomotion1.51.83.71.2-1.4-1.9-1.41.3-1.41.4-1.5-1.01.11.0
Patch foraging indifference point 0 sec0.20.30.6-0.80.60.50.5-0.50.6-0.6-0.10.8-0.6-0.7
Patch foraging indifference point AUC0.80.91.7-1.31.30.31.3-1.10.6-0.60.31.2-0.9-0.9
Delay disc. indifference point, 0s delay0.60.72.10.6-0.2-0.7-0.90.3-1.41.4-1.10.1-0.4-0.7
Delay disc. indifference point, 16s delay0.20.20.50.2-0.0-0.5-0.40.1-0.60.6-0.70.2-0.0-0.1
Delay disc. indifference point, 2s delay1.21.32.91.4-1.0-1.5-1.00.8-1.71.7-1.0-0.40.60.3
Delay disc. indifference point, 24s delay0.10.10.6-0.1-0.20.1-0.40.4-0.40.4-0.8-0.0-0.1-0.1
Delay disc. indifference point, 4s delay0.30.31.60.3-0.20.1-0.90.3-0.50.5-1.30.1-0.4-0.7
Delay disc. indifference point, 8s delay0.60.62.00.6-0.90.2-1.41.2-0.40.4-0.9-1.00.20.2
Indifference point function ln k1.31.82.81.7-1.7-1.4-1.71.1-1.51.5-1.0-1.21.10.8
Indifference point function log k1.31.82.81.7-1.7-1.4-1.71.1-1.51.5-1.0-1.21.10.8
Patch foraging total patch changes 0 sec0.20.40.9-0.90.60.70.5-0.30.8-0.80.00.6-0.5-0.5
Patch foraging total patch changes 12 sec4.05.28.1-2.82.72.62.2-2.12.2-2.20.82.3-2.4-2.2
Patch foraging total patch changes 18 sec0.40.51.4-1.00.60.41.2-0.50.7-0.70.70.6-0.3-0.3
Patch foraging total patch changes 24 sec3.54.27.8-2.32.71.91.5-2.31.3-1.3-0.62.1-2.7-2.8
Patch foraging total patch changes 6 sec0.20.30.6-0.40.60.40.3-0.60.4-0.4-0.60.7-0.6-0.7
Patch foraging time to switch 0 sec0.10.20.60.30.5-0.2-0.1-0.3-0.80.8-0.10.4-0.5-0.6
Patch foraging water rate 0 sec0.30.51.40.4-1.0-0.6-0.20.70.2-0.2-0.3-0.41.11.2
Patch foraging water rate 12 sec0.40.61.70.9-1.3-0.6-0.80.5-0.30.3-0.6-0.80.90.8
Patch foraging water rate 18 sec0.70.91.90.8-1.2-0.5-1.41.1-0.40.4-1.3-1.01.00.9
Patch foraging water rate 24 sec0.40.61.31.1-1.2-0.3-0.60.7-0.20.2-0.1-0.71.01.0
Patch foraging water rate 6 sec0.40.61.40.5-1.2-0.2-0.90.70.1-0.1-0.7-1.00.90.9
Seeking ratio, delayed vs. immediate footshock0.20.20.9-0.00.2-0.2-0.1-0.6-0.50.5-0.90.3-0.3-0.7
Distance traveled before self-admin1.31.33.1-0.61.40.51.8-1.70.5-0.51.41.6-0.8-0.9
Distance traveled after self-admin0.10.10.5-0.10.4-0.20.7-0.5-0.10.10.40.70.0-0.1
Extensor digitorum longus weight3.915.327.0-3.84.93.53.0-4.82.2-2.20.34.9-5.0-5.2
Bone: elastic displacement0.60.61.6-0.3-0.50.40.40.91.0-1.01.3-0.80.40.9
Bone: elastic work1.21.52.8-1.70.91.41.4-0.81.7-1.71.20.8-0.9-0.6
Bone: endosteal estimation2.35.110.32.9-1.8-2.7-2.30.8-3.23.2-2.7-1.11.50.6
Bone: endosteal perimeter3.47.012.83.6-2.1-3.3-2.81.2-3.53.5-2.8-1.62.01.1
Epididymis fat weight1.02.35.22.1-1.2-1.6-1.6-0.1-2.12.1-2.3-0.50.8-0.1
Delta time in closed arm before/after self-admin3.93.76.1-2.21.92.51.5-2.31.4-1.40.12.0-2.3-2.4
Delta time in open arm before/after self-admin0.70.71.7-1.21.30.71.0-0.50.5-0.50.41.0-1.0-0.6
Diff in mean of infusions in LGA sessions2.52.84.2-1.91.81.81.8-1.32.1-2.11.71.3-1.3-1.0
Delay discount exponential model param0.40.41.0-0.50.50.41.0-0.80.8-0.81.00.3-0.10.0
Extinction: sum of active levers before priming2.02.03.1-1.51.71.81.0-1.41.2-1.20.41.5-1.7-1.5
Active lever presses in extinction session 61.71.62.5-1.21.41.21.5-1.11.6-1.61.40.9-1.0-0.6
Bone: final force0.40.71.3-1.01.10.11.0-1.10.4-0.4-0.11.1-0.9-1.0
Bone: final moment0.40.71.2-1.01.10.11.0-1.10.4-0.4-0.11.1-0.9-0.9
Food consumed during 24 hour testing period0.40.51.50.7-0.7-0.7-0.10.7-0.00.00.4-0.81.01.2
Glucose2.43.66.72.1-2.2-2.2-1.81.4-2.62.6-1.2-1.31.61.1
Heart weight0.60.92.11.0-0.8-0.3-1.50.8-1.31.3-1.2-0.50.40.2
Delay discount hyperbolic model param0.50.51.1-0.60.50.51.0-0.80.9-0.91.10.3-0.10.1
Intermittent access intake day 1-15 change0.80.82.40.7-1.0-1.10.20.80.3-0.30.6-0.81.41.6
Intermittent access intake escalation0.40.41.30.4-0.6-0.80.40.40.4-0.40.6-0.51.01.1
Intermittent access intake escalation 20.30.30.9-0.00.0-0.20.9-0.20.7-0.70.70.30.50.6
Intermitt. access day 1 inactive lever presses1.92.14.81.5-1.0-1.7-1.60.8-2.22.2-1.6-0.60.70.4
Intermitt. access day 15 inactive lever presses1.41.54.71.0-0.0-1.8-0.9-0.5-1.81.8-2.20.4-0.1-0.6
Intermitt. access escalation Index1.71.54.20.9-0.9-0.7-1.81.0-1.51.5-2.1-1.10.40.2
Intermittent access day 1 total infusions2.32.66.71.5-0.8-2.2-1.90.4-2.32.3-2.6-0.20.2-0.4
Intermittent access day 15 total infusions2.83.18.11.9-1.8-2.8-1.71.4-1.61.6-1.7-1.31.71.3
Intermittent access terminal intake (last 3 days)0.91.04.31.0-0.6-2.1-0.60.2-1.11.1-1.40.10.60.2
Intermittent access total infusions1.51.74.91.3-0.8-2.2-1.20.6-1.61.6-1.8-0.30.60.2
Intermittent access day 1 locomotion2.02.07.30.8-0.2-1.4-1.70.1-2.12.1-2.70.2-0.4-0.9
Intermittent access day 15 total locomotion0.60.72.00.40.2-1.3-0.4-0.3-1.01.0-1.40.6-0.4-0.7
Intermittent access total locomotion2.32.77.01.2-0.2-2.4-1.3-0.2-2.52.5-2.60.6-0.2-0.8
Intermittent access standard deviation0.70.72.0-0.5-0.00.11.1-0.11.4-1.41.30.20.40.7
Left kidney weight0.51.46.10.8-0.3-0.6-1.7-0.0-1.51.5-2.5-0.20.1-0.5
Right kidney weight0.20.72.50.50.1-0.5-0.9-0.4-1.31.3-1.60.3-0.2-0.6
Cocaine induced anxiety0.30.30.7-0.60.80.40.8-0.70.2-0.20.60.5-0.6-0.4
Post-drug Anxiety0.70.81.7-0.61.10.51.3-1.10.5-0.51.30.9-0.8-0.7
Baseline Anxiety0.91.01.1-0.91.11.01.0-1.01.1-1.10.90.9-1.0-0.9
Tail length0.82.56.8-1.91.42.61.2-1.42.0-2.00.51.1-1.1-1.0
Length with tail1.03.67.7-1.82.22.11.1-2.81.2-1.2-0.72.4-1.8-2.4
Length without tail0.61.43.8-0.71.30.20.6-2.00.0-0.0-0.81.9-1.1-1.7
Times rat made contact with spout0.60.71.4-1.10.60.91.0-0.31.2-1.21.00.4-0.4-0.2
Lifetime Intake1.01.12.80.9-0.7-1.7-1.20.6-1.31.3-1.6-0.30.30.0
Liver weight, left0.50.81.70.8-1.3-0.8-0.70.9-0.30.3-0.1-1.01.31.2
Liver weight, right0.10.21.0-0.0-0.4-1.00.3-0.4-0.50.5-0.20.10.30.0
Locomotor activity0.30.41.30.1-1.1-0.3-0.10.8-0.40.4-0.3-0.80.90.9
Locomotor testing distance0.30.51.50.1-1.1-0.6-0.31.0-0.60.6-0.3-1.20.60.8
Locomotor testing rearing0.30.51.10.2-0.9-1.00.30.8-0.30.30.4-1.10.91.0
Locomotion in novel chamber2.53.07.42.7-1.8-2.6-1.01.0-1.91.9-0.3-1.01.91.5
Locomotion in novel chamber post-restriction0.50.61.30.6-1.0-0.0-0.61.10.1-0.10.3-1.10.91.1
Fecal boli incidents, locomotor time 10.70.72.00.10.5-1.21.4-1.0-0.30.31.41.00.40.1
Change in fecal boli incidents, locomotor task1.51.43.81.1-1.5-0.1-2.01.2-1.11.1-1.5-1.40.60.4
Time >=10cm from walls, locomotor time 11.81.83.91.6-0.9-2.0-1.11.0-1.91.9-0.9-0.71.10.9
Bouts of movement, locomotor time 13.74.18.3-2.21.91.22.9-2.12.5-2.52.31.7-0.7-0.6
Total resting periods, locomotor time 12.42.65.6-1.71.50.72.4-1.82.0-2.01.91.5-0.4-0.4
Rest time, locomotor task time 10.20.20.80.5-0.5-0.9-0.10.1-0.00.00.1-0.40.80.5
Distance moved, locomotor task time 10.10.20.30.4-0.10.5-0.50.6-0.40.4-0.2-0.3-0.5-0.2
Vertical activity count, locomotor time 11.61.75.41.1-1.50.0-1.72.3-0.70.7-0.8-1.80.71.3
Time >=10cm from walls, locomotor time 20.40.41.30.6-0.4-0.6-0.00.7-0.30.30.4-0.21.01.1
Bouts of movement, locomotor time 25.55.910.0-3.02.91.83.2-2.51.9-1.91.82.7-2.4-2.1
Total resting periods, locomotor time 24.85.19.1-2.82.71.53.0-2.31.7-1.71.72.6-2.3-2.0
Rest time, locomotor task time 20.20.20.60.5-0.7-0.8-0.40.3-0.40.4-0.3-0.50.40.2
Distance moved, locomotor task time 20.20.20.70.3-0.20.60.00.80.3-0.30.8-0.40.30.7
Vertical activity count, locomotor time 20.91.03.20.1-1.01.3-0.71.80.6-0.60.5-1.30.51.3
Light reinforcement 10.30.51.50.3-0.6-1.1-0.10.8-0.20.20.3-1.01.11.2
Light reinforcement 21.92.54.11.5-1.0-2.0-1.71.0-1.81.8-1.8-1.41.71.3
Bone: marrow area2.55.410.63.0-1.9-2.7-2.30.9-3.33.3-2.7-1.21.60.7
Bone: maximum diameter0.30.52.00.8-0.2-1.0-0.7-0.3-0.90.9-1.40.10.4-0.1
Bone: maximum force0.50.91.8-0.21.1-0.40.2-1.3-0.50.5-1.21.3-0.9-1.3
Bone: maximum moment0.50.81.6-0.31.1-0.40.3-1.2-0.50.5-1.11.2-0.9-1.3
Mean time between licks in bursts1.11.63.9-2.01.31.80.6-0.11.4-1.40.30.4-1.8-1.2
Mean num. licks in bursts0.50.61.9-1.00.20.60.80.41.1-1.11.4-0.3-0.00.5
Cd content in liver1.01.12.00.9-1.3-1.4-0.21.2-0.50.51.0-1.01.31.4
Co content in liver1.01.22.90.3-1.20.00.01.50.7-0.71.4-1.21.21.7
Cu content in liver0.40.41.9-0.90.41.4-0.1-0.30.6-0.6-0.30.0-0.7-0.6
Fe content in liver0.10.20.7-0.20.40.40.2-0.60.1-0.1-0.10.8-0.4-0.4
K content in liver0.50.53.5-0.00.3-0.5-0.7-0.1-0.40.4-1.9-0.0-0.5-0.7
Mg content in liver0.40.42.10.00.1-1.0-0.3-0.3-0.70.7-1.40.0-0.4-0.7
Mn content in liver0.40.50.9-0.50.90.70.1-0.30.6-0.6-0.80.6-0.9-0.9
Na content in liver0.10.10.3-0.50.4-0.40.30.10.0-0.00.3-0.3-0.2-0.0
Rb content in liver0.91.11.91.1-1.3-1.4-0.90.6-1.01.0-1.0-1.11.00.7
Se content in liver0.30.41.3-0.40.80.4-0.3-0.60.0-0.0-1.10.8-0.7-1.0
Sr content in liver6.76.18.6-2.92.82.62.5-2.51.9-1.91.52.6-2.9-2.6
Zn content in liver2.73.05.9-2.42.31.11.7-1.61.4-1.40.31.5-2.2-1.8
Bone: minimum diameter2.24.28.32.2-1.5-2.9-1.90.7-2.72.7-2.9-1.01.30.6
Time in familiar zone, hab. session 10.20.20.8-0.40.2-0.60.5-0.9-0.20.2-0.50.6-0.0-0.3
Time in novel zone, hab. session 10.90.82.10.9-1.0-0.3-0.81.5-0.30.30.6-1.40.91.2
Total zone transitions, hab. session 10.50.61.4-1.00.70.90.6-0.51.2-1.20.50.5-0.8-0.6
Total locomotion distance, hab. session 10.20.20.50.10.3-0.3-0.1-0.5-0.50.5-0.60.5-0.6-0.7
Locomotion velocity, hab. session 10.40.51.2-0.60.90.30.4-1.00.1-0.1-0.20.9-1.1-1.1
Time in familiar zone, hab. session 20.50.51.30.4-0.9-0.5-0.20.7-0.10.10.8-0.91.11.2
Time in novel zone, hab. session 20.40.41.1-0.50.80.40.5-0.60.1-0.1-0.40.8-1.0-0.9
Total zone transitions, hab. session 20.50.71.9-1.40.90.30.9-0.80.8-0.80.10.8-1.0-0.8
Total locomotion distance, hab. session 20.20.30.6-0.80.6-0.10.2-0.7-0.10.1-0.50.6-0.8-0.8
Locomotion velocity, hab. session 20.20.20.6-0.40.4-0.4-0.0-0.5-0.40.4-0.80.4-0.6-0.6
Novel to familiar place preference ratio0.80.91.9-0.71.11.40.1-0.90.4-0.4-0.71.0-1.3-1.3
Novelty place preference0.60.61.5-0.50.91.2-0.2-0.70.2-0.2-0.80.8-1.0-1.1
Time in novel zone, NPP test1.01.02.1-0.81.21.40.1-1.10.2-0.2-0.61.2-1.4-1.5
Total zone transitions, NPP test1.11.53.2-1.81.31.11.2-1.01.3-1.30.71.0-1.3-1.0
Total locomotion distance, NPP test0.10.10.5-0.70.30.20.2-0.20.2-0.2-0.30.2-0.6-0.5
Locomotion velocity, NPP test0.00.10.2-0.4-0.00.1-0.20.30.2-0.2-0.4-0.3-0.10.0
Intraocular pressure0.20.20.7-0.50.30.80.20.00.6-0.60.7-0.3-0.10.0
Delta distance traveled before/after self-admin0.40.41.20.2-0.8-0.1-0.91.1-0.20.2-0.7-0.70.50.6
Delta ambulatory time before/after self-admin0.40.41.60.2-0.9-0.1-0.71.2-0.10.1-0.2-0.90.70.9
Parametrial fat weight2.85.510.83.0-1.8-2.6-2.60.9-3.33.3-2.8-0.81.80.7
Pavlov. Cond. lever latency0.10.10.50.4-0.20.7-0.2-0.10.2-0.20.5-0.10.20.2
Pavlov. Cond. magazine entry latency0.20.20.5-0.30.7-0.70.6-0.5-0.20.20.10.7-0.5-0.6
Pavlov. Cond. change in total contacts0.10.10.8-0.10.2-0.90.50.2-0.20.20.20.00.10.2
Pavlov. Cond. index score0.10.10.5-0.30.3-0.70.7-0.10.0-0.00.40.3-0.0-0.0
Pavlov. Cond. latency score0.10.10.9-0.1-0.0-1.00.40.1-0.10.10.20.00.20.2
Pavlov. Cond. lever contacts0.20.21.00.1-0.3-1.0-0.10.6-0.50.5-0.4-0.40.40.4
Pavlov. Cond. magazine entry number0.30.31.20.4-0.70.2-1.00.3-0.50.5-1.1-0.60.20.1
Pavlov. Cond. intertrial magazine entries0.20.20.8-0.60.0-0.10.9-0.40.5-0.50.40.30.20.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.7-0.50.5-0.50.9-0.20.1-0.10.40.4-0.2-0.2
Pavlov. Cond. response bias0.10.10.5-0.30.5-0.50.7-0.0-0.10.10.30.3-0.2-0.1
Pavlov. Cond. lever latency0.50.71.40.5-1.10.5-0.71.20.6-0.60.7-1.20.81.0
Pavlov. Cond. magazine entry latency3.74.38.2-2.22.91.42.4-2.61.1-1.10.92.7-2.3-2.1
Pavlov. Cond. change in total contacts1.01.43.3-1.01.7-0.51.7-1.80.1-0.10.41.8-0.9-0.9
Pavlov. Cond. index score2.32.97.0-1.32.40.32.0-2.60.2-0.20.32.6-1.7-1.9
Pavlov. Cond. latency score2.12.66.5-1.22.30.21.8-2.60.0-0.00.12.5-1.6-1.8
Pavlov. Cond. lever contacts1.01.33.1-1.11.5-0.11.8-1.70.1-0.10.61.7-1.0-1.0
Pavlov. Cond. magazine entry number6.07.313.62.5-3.7-1.8-2.93.6-1.41.4-1.0-3.73.02.9
Pavlov. Cond. intertrial magazine entries1.11.53.01.3-1.7-1.2-0.71.3-0.70.70.4-1.41.61.4
Pavlov. Cond. lever-magazine prob. diff.2.63.37.6-1.52.50.42.2-2.80.3-0.30.52.7-1.8-1.9
Pavlov. Cond. response bias1.62.24.4-1.52.10.41.9-2.00.5-0.50.52.0-1.6-1.5
Time in closed arm before self-admin0.50.62.11.0-0.4-1.40.00.3-0.90.90.30.00.90.7
Time in closed arm after self-admin0.10.10.20.3-0.3-0.40.1-0.5-0.20.2-0.20.30.3-0.1
Time in open arm before self-admin0.70.71.90.1-1.20.8-1.11.20.5-0.5-0.6-1.40.40.6
Time in open arm after self-admin0.50.51.7-0.90.11.30.10.81.0-1.00.5-0.5-0.20.4
Bone: periosteal estimation1.02.04.51.7-0.8-2.0-1.2-0.0-2.02.0-2.1-0.30.90.2
Bone: periosteal perimeter0.50.82.81.0-0.5-1.7-0.5-0.2-1.21.2-0.9-0.10.70.3
Bone: post-yield work3.34.48.32.8-1.3-2.8-2.10.6-2.92.9-2.7-0.81.30.5
Progressive ratio test 1 active lever presses1.11.11.80.9-1.2-1.4-1.11.4-0.70.7-0.9-1.11.11.1
Progressive ratio test 1 breakpoint1.01.11.90.9-1.2-1.2-1.01.4-0.50.5-0.6-1.11.21.2
Progressive ratio test 1 inactive lever presses0.50.51.3-0.30.7-0.0-0.1-0.6-0.40.4-1.10.9-1.0-1.2
Progressive ratio test 2 active lever presses1.51.64.31.4-1.2-2.1-1.21.1-1.31.3-1.1-0.71.21.0
Progressive ratio test 2 breakpoint2.12.45.41.7-1.6-2.3-1.51.5-1.41.4-1.2-1.21.61.4
Progressive ratio test 2 inactive lever presses1.11.24.30.9-0.6-2.1-1.00.3-1.41.4-1.80.00.40.1
Incentive Sensitization - Responses0.30.31.10.6-0.1-1.0-0.30.1-0.90.9-0.60.30.20.0
Incentive Sensitization - Breakpoint0.60.61.80.8-0.3-1.3-0.60.2-1.21.2-0.90.20.30.0
Sum of active levers in priming session hrs 5-60.80.81.6-1.00.90.71.1-0.51.3-1.31.10.5-0.4-0.1
Progressive ratio0.10.10.40.4-0.0-0.4-0.60.1-0.00.0-0.6-0.20.0-0.0
Food seeking constrained by brief footshock0.10.20.7-0.4-0.20.4-0.50.80.1-0.1-0.0-0.80.10.4
Seeking ratio, punishment vs. effort0.10.10.6-0.8-0.10.70.10.20.0-0.00.0-0.2-0.3-0.1
Retroperitoneal fat weight3.110.217.84.2-3.4-3.2-3.71.7-3.83.8-3.6-2.22.71.4
Reaction time number correct0.71.12.7-0.60.60.51.5-1.60.8-0.81.61.5-0.1-0.4
Reaction time mean minus median0.71.03.2-0.90.90.51.4-0.90.9-0.91.80.7-0.6-0.4
Reaction time mean minus median AUC1.31.76.2-1.20.80.81.8-1.01.5-1.52.50.7-0.4-0.2
Reaction time num false alarms0.20.30.8-0.6-0.50.9-0.10.30.9-0.9-0.3-0.20.20.2
Reaction time num false alarms AUC0.50.72.5-1.1-0.11.60.10.21.4-1.4-0.00.0-0.2-0.0
Reaction time trials correct on left0.71.12.7-0.60.60.51.5-1.60.8-0.81.61.5-0.1-0.4
Reaction time trials on left0.91.23.0-0.70.70.61.6-1.70.9-0.91.71.5-0.1-0.4
Reaction time mean0.30.52.3-0.60.4-0.11.0-0.40.7-0.71.50.2-0.3-0.0
Reaction time mean AUC0.20.31.8-0.30.2-0.40.7-0.30.6-0.61.40.0-0.00.2
Median of all reaction times0.20.20.8-0.40.5-0.10.7-0.50.5-0.50.90.3-0.4-0.2
Reaction time omissions0.70.92.5-0.70.31.01.0-0.71.5-1.51.60.5-0.0-0.1
Reaction time false alarm rate0.40.51.4-0.4-0.50.8-0.91.00.5-0.5-1.2-0.80.00.2
Reaction time premature initiation rate0.70.92.5-0.61.30.8-0.0-0.70.3-0.3-1.01.0-1.5-1.6
Reaction time premature initiations1.52.13.7-1.21.81.51.2-1.81.2-1.20.41.9-1.6-1.7
Std. dev. reaction times0.71.04.2-0.80.30.51.3-0.51.4-1.42.00.2-0.00.2
Reaction time trials completed0.91.23.0-0.70.70.61.6-1.70.9-0.91.71.5-0.1-0.4
Reaction time trials AUC0.71.12.7-0.60.60.41.5-1.60.7-0.71.61.5-0.1-0.4
Run reversals in cocaine runway, females0.50.51.80.20.20.1-0.6-0.4-0.70.7-1.30.4-0.7-1.1
Run reversals in cocaine runway, males1.91.83.91.1-1.6-0.8-1.52.0-0.70.7-0.8-1.91.41.6
Latency to leave start box in cocaine runway2.22.44.32.0-1.2-1.8-1.80.8-2.12.1-1.9-0.61.10.5
Latency to leave start box in cocaine runway, F0.50.51.30.8-0.2-1.0-0.50.1-1.11.1-1.00.30.3-0.0
Latency to leave start box in cocaine runway, M4.13.96.42.5-2.2-1.8-2.41.9-1.71.7-1.1-2.12.21.8
Std. dev. time between licks in bursts0.30.41.20.1-0.6-0.1-0.91.1-0.20.2-0.7-1.00.30.6
Total sessions with >9 infusions0.91.01.91.0-0.8-1.2-1.40.8-1.41.4-1.2-0.50.30.0
Short access day 1 total inactive lever presses1.01.12.10.9-0.9-1.2-1.40.8-1.41.4-1.4-0.60.50.2
Short access day 10 total inactive lever presses1.31.43.00.8-1.3-0.6-1.71.7-1.01.0-1.1-1.40.81.0
Short access day 1 total infusions0.30.30.60.5-0.5-0.7-0.70.5-0.80.8-0.6-0.30.20.0
Short access day 10 total infusions1.61.85.81.0-0.4-1.6-1.70.3-1.81.8-2.4-0.2-0.2-0.7
Short access total infusions0.50.51.80.5-0.2-0.8-0.90.2-1.01.0-1.30.0-0.3-0.5
Short access day 1 locomotion0.40.41.3-0.40.50.0-0.3-0.4-0.50.5-1.10.6-0.8-1.0
Short access day 10 total locomotion1.01.13.50.30.4-0.8-0.8-0.5-1.51.5-1.90.6-0.8-1.2
Short access total locomotion1.01.13.4-0.20.7-0.4-0.6-0.7-1.11.1-1.80.8-1.2-1.6
One hour access (0.3 mA shock)2.73.26.31.8-1.8-2.5-1.81.4-1.81.8-2.0-1.31.61.3
Compulsive drug intake2.22.26.0-1.81.22.41.4-0.81.8-1.81.60.8-1.2-0.7
One hour access (shock baseline)4.34.910.42.4-2.3-3.2-2.11.9-2.02.0-1.9-1.92.42.0
Social response proportion0.20.30.80.5-0.7-0.4-0.60.40.1-0.1-0.4-0.20.90.7
Social responses0.30.41.2-0.1-0.50.30.20.51.1-1.10.4-0.20.81.0
Social time0.71.02.4-1.00.11.20.90.21.6-1.61.50.10.00.5
Soleus weight1.85.37.92.3-2.8-2.7-1.82.5-1.51.5-1.2-2.62.82.8
Bone: stiffness0.10.20.70.40.3-0.6-0.1-0.5-0.50.5-0.80.40.1-0.2
Tibialis anterior weight6.722.932.5-5.35.74.64.4-5.33.7-3.72.25.4-5.6-5.4
Time to tail flick, vehicle, before self-admin0.40.40.90.10.6-0.3-0.2-0.5-0.80.8-0.70.9-0.6-0.9
Time to tail flick, vehicle, after self-admin0.70.71.9-0.41.00.60.5-1.40.2-0.20.31.2-1.0-1.3
Time to tail flick, test, before self-admin0.50.51.20.5-0.0-0.3-0.5-0.5-1.11.1-1.10.3-0.5-0.9
Time to tail flick, test, after self-admin0.20.20.80.5-0.6-0.1-0.10.9-0.20.20.2-0.50.60.8
Delta time to tail flick, vehicle, before/after SA0.20.20.4-0.40.20.30.5-0.60.5-0.50.60.2-0.1-0.2
Delta time to tail flick, test, before/after SA0.90.81.9-0.90.30.90.90.61.4-1.41.1-0.20.20.8
Tibia length0.51.34.2-0.21.40.11.2-2.00.2-0.20.12.0-1.0-1.4
Ambulatory time before self-admin1.01.02.9-0.41.20.11.7-1.20.6-0.61.41.4-0.5-0.5
Ambulatory time after self-admin0.30.41.40.60.1-1.20.3-0.3-0.90.9-0.30.70.20.0
Bone: tissue strength0.70.61.50.5-0.8-0.8-0.81.2-0.40.4-0.4-1.10.81.0
Total heroin consumption4.45.28.7-2.42.23.02.2-1.62.9-2.92.31.6-2.0-1.4
Bone: trabecular number0.20.31.00.20.5-0.3-0.4-0.3-0.60.6-1.00.4-0.5-0.7
Bone: trabecular spacing0.50.72.5-0.80.00.31.10.21.1-1.11.6-0.10.10.6
Bone: trabecular thickness0.70.92.11.4-0.9-1.5-0.60.1-0.90.9-0.9-0.31.10.6
Bone: trabecular tissue density1.62.24.41.5-2.1-1.5-0.91.5-0.90.9-0.3-1.62.11.9
Water consumed over 24 hours0.20.30.7-0.20.40.70.3-0.60.9-0.9-0.30.4-0.1-0.2
Number of responses in last shaping day0.30.30.8-0.90.40.90.2-0.10.7-0.70.10.2-0.5-0.4