Hub : Genes

LOC685453

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression LOC685453 0.18 0.17 1.9e-03 0.13 0.1 0.14 0.13 4.7e-04 2.3e-03 4.4e-04 5.1e-04
2 Liver gene expression LOC685453 0.21 0.18 3.5e-14 0.08 0.09 0.08 0.08 2.2e-09 5.7e-10 2.1e-09 1.9e-09
3 Adipose gene expression LOC685453 0.16 0.11 2.5e-15 0.08 0.09 0.09 0.09 1.3e-09 2.5e-10 4.7e-10 7.4e-10
4 OFC gene expression LOC685453 0.29 0.21 1.9e-04 0.09 0.13 0.1 0.11 4.3e-03 6.0e-04 2.6e-03 1.2e-03
5 Brain gene expression LOC685453 0.17 0.09 0.0e+00 0.19 0.2 0.2 0.2 4.7e-17 3.8e-18 4.2e-18 3.5e-18
6 NAcc gene expression LOC685453 0.12 0.11 3.0e-11 0.1 0.09 0.09 0.09 3.1e-11 1.6e-10 9.4e-11 1.2e-10
7 BLA gene expression LOC685453 0.08 0.08 6.0e-04 0.05 0.05 0.04 0.04 1.4e-03 8.8e-04 2.4e-03 2.7e-03
8 pVTA gene expression LOC685453 0.22 0.15 5.3e-09 0.18 0.18 0.18 0.18 3.5e-08 2.2e-08 1.9e-08 2.7e-08
9 IL gene expression LOC685453 0.15 0.14 7.6e-03 0.06 0.06 0.02 0.06 1.3e-02 1.7e-02 9.8e-02 1.8e-02
10 PL gene expression LOC685453 0.14 0.12 4.9e-13 0.11 0.11 0.11 0.11 1.1e-11 6.4e-12 2.7e-12 4.4e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.20.20.4-0.4-0.4-0.4-0.50.5-0.40.50.50.4
Area under the delay curve0.20.20.50.5-0.2-0.4-0.4-0.50.2-0.40.70.7-0.5
BMI with tail0.10.20.5-0.70.50.40.40.5-0.30.3-0.5-0.6-0.3
BMI without tail0.20.50.6-0.70.70.60.70.7-0.60.6-0.7-0.8-0.6
Body weight0.00.20.50.3-0.4-0.5-0.5-0.40.7-0.50.50.40.3
Weight adjusted by age2.22.53.1-1.61.51.61.61.5-1.71.6-1.5-1.5-1.8
Bone surface2.23.94.3-2.11.92.02.02.0-1.92.0-2.0-2.0-1.9
Bone volume0.61.01.1-1.11.01.01.01.0-0.91.0-1.1-1.1-0.9
Breakpoint value in progressive ratio session0.40.41.21.1-0.9-0.6-0.6-0.70.4-0.50.40.50.3
Number of licking bursts0.00.00.1-0.10.00.10.2-0.0-0.40.2-0.3-0.30.2
Context. condit. distance diff. score2.83.44.02.0-1.8-1.8-1.9-1.91.9-1.81.91.81.5
Locomotion velocity, session 10.10.10.2-0.50.40.30.30.4-0.30.3-0.3-0.3-0.3
Locomotion distance, session 10.60.81.01.0-0.9-0.9-0.9-0.80.9-0.90.90.90.7
Locomotion velocity, session 20.10.10.3-0.40.20.30.40.4-0.20.3-0.6-0.6-0.3
Locomotion distance, session 20.20.30.6-0.50.50.50.50.6-0.50.5-0.5-0.4-0.8
Locomotion velocity, session 30.10.10.20.4-0.3-0.2-0.1-0.10.2-0.10.00.0-0.5
Locomotion distance, session 30.00.00.40.2-0.00.00.0-0.1-0.10.10.00.1-0.6
Stereotopy head waving bouts, day 30.50.61.11.0-0.9-0.8-0.8-0.70.8-0.70.70.7-0.0
Stereotopy head waving duration, day 30.91.01.41.1-1.1-1.1-1.0-1.01.2-1.10.90.90.7
Locomotion velocity, session 70.60.71.41.2-1.1-0.9-0.8-0.81.0-0.80.60.60.3
Locomotion distance, session 70.40.60.80.9-0.8-0.7-0.7-0.80.8-0.70.60.60.7
Stereotopy head waving bouts, day 71.01.11.9-1.00.80.91.01.1-0.81.0-1.2-1.2-1.4
Stereotopy head waving duration, day 71.21.52.7-1.21.11.11.11.2-1.01.1-1.2-1.2-1.6
Locomotion velocity, session 80.40.50.60.8-0.6-0.7-0.7-0.70.7-0.70.80.80.3
Locomotion distance, session 80.81.21.31.2-1.1-1.1-1.1-1.01.1-1.11.11.10.8
Degree of sensitization distance0.00.00.2-0.20.00.10.10.1-0.10.1-0.3-0.30.4
Degree of sensitization stereotypy1.21.31.8-1.21.01.11.11.2-1.01.1-1.2-1.2-1.3
Conditioned locomotion0.10.10.10.3-0.3-0.3-0.2-0.00.3-0.20.10.1-0.3
Cocaine response after cond. corrected0.50.61.0-0.60.50.60.70.6-0.70.7-0.9-1.0-0.9
Cocaine response after cond. not corrected0.40.40.8-0.50.40.60.60.5-0.60.6-0.8-0.9-0.9
Cocaine response before conditioning0.00.00.0-0.0-0.0-0.0-0.0-0.10.1-0.00.00.10.1
Saline control response0.10.10.20.0-0.1-0.3-0.3-0.20.3-0.30.40.40.3
Bone: connectivity density2.03.24.1-2.01.91.81.81.7-1.71.8-1.7-1.7-1.7
Bone: cortical apparent density8.010.511.83.4-3.3-3.3-3.3-3.33.3-3.33.33.32.8
Bone: cortical area0.20.20.5-0.70.50.50.50.5-0.40.4-0.4-0.4-0.5
Bone: cortical porosity0.50.50.7-0.90.80.70.70.7-0.60.7-0.7-0.7-0.7
Bone: cortical porosity0.70.71.1-1.10.90.80.80.8-0.70.8-0.9-0.9-0.7
Bone: cortical thickness0.20.40.60.5-0.6-0.7-0.7-0.60.7-0.70.70.70.6
Bone: cortical thickness0.00.00.20.1-0.2-0.2-0.1-0.00.2-0.20.0-0.00.5
Bone: cortical tissue density7.810.311.63.4-3.2-3.2-3.2-3.33.2-3.23.23.22.8
Condit. Reinf. active minus inactive responses0.20.20.5-0.70.70.50.40.4-0.50.3-0.1-0.0-0.1
Condit. Reinf. active-inactive response ratio0.00.00.2-0.20.20.0-0.10.0-0.0-0.10.40.4-0.0
Condit. Reinf. active responses0.70.81.6-1.31.21.00.91.0-1.00.9-0.6-0.5-0.5
Condit. Reinf. inactive responses0.30.40.7-0.80.80.70.60.7-0.60.6-0.6-0.5-0.4
Incentive salience index mean0.20.30.8-0.90.80.60.40.6-0.60.4-0.1-0.1-0.0
Condit. Reinf. lever presses0.10.10.5-0.20.1-0.2-0.3-0.10.2-0.30.40.50.7
Condit. Reinf. active minus inactive responses1.11.41.81.2-1.1-1.1-1.2-1.21.2-1.21.31.41.0
Condit. Reinf. active-inactive response ratio0.40.40.60.6-0.6-0.6-0.7-0.60.7-0.70.70.80.6
Condit. Reinf. active responses0.70.91.70.9-0.8-0.9-1.0-0.90.9-1.01.21.30.7
Condit. Reinf. inactive responses1.21.52.31.2-1.0-1.1-1.2-1.21.1-1.21.51.50.9
Condit. Reinf. lever presses3.34.55.2-2.32.22.22.12.1-2.22.1-2.0-1.9-2.1
Condit. Reinf. lever reinforcers received0.20.30.70.5-0.3-0.4-0.5-0.50.5-0.50.80.90.3
Conditioned reinforcement - actives0.20.20.40.2-0.3-0.4-0.4-0.10.4-0.40.50.50.6
Conditioned reinforcement - inactives0.30.40.70.6-0.5-0.6-0.6-0.60.6-0.60.80.80.1
Conditioned locomotion0.10.20.70.1-0.3-0.3-0.3-0.00.3-0.40.30.50.9
Patch foraging indifference point 0 sec6.810.913.1-3.63.33.23.23.2-3.23.2-3.2-3.2-3.6
Patch foraging indifference point AUC1.01.22.5-1.21.11.01.01.0-0.81.0-1.0-1.0-1.6
Delay disc. indifference point, 0s delay2.62.93.31.8-1.8-1.7-1.7-1.71.8-1.71.81.71.1
Delay disc. indifference point, 16s delay1.31.32.3-1.11.31.21.11.2-1.31.1-0.8-0.7-1.5
Delay disc. indifference point, 2s delay0.20.20.40.6-0.4-0.4-0.4-0.50.4-0.30.60.6-0.5
Delay disc. indifference point, 24s delay0.10.10.20.2-0.1-0.2-0.2-0.10.0-0.20.40.4-0.3
Delay disc. indifference point, 4s delay2.02.13.31.5-1.3-1.4-1.5-1.61.2-1.51.81.80.8
Delay disc. indifference point, 8s delay1.21.31.91.2-1.0-1.1-1.2-1.21.0-1.21.41.40.4
Indifference point function ln k0.40.61.30.9-0.9-0.7-0.7-0.70.6-0.70.40.51.1
Indifference point function log k0.40.61.30.9-0.9-0.7-0.7-0.70.6-0.70.40.51.1
Patch foraging total patch changes 0 sec6.29.912.2-3.53.23.13.13.1-2.93.0-3.1-3.1-3.4
Patch foraging total patch changes 12 sec1.41.83.7-1.41.51.31.31.2-1.31.3-1.1-1.1-1.9
Patch foraging total patch changes 18 sec2.63.35.7-2.22.01.81.71.7-1.51.6-1.5-1.6-2.4
Patch foraging total patch changes 24 sec1.62.02.5-1.51.31.31.41.4-1.21.3-1.5-1.5-1.6
Patch foraging total patch changes 6 sec2.84.15.8-2.42.22.02.02.0-1.81.9-1.8-1.8-2.3
Patch foraging time to switch 0 sec1.52.32.91.7-1.4-1.4-1.5-1.61.1-1.41.71.71.6
Patch foraging water rate 0 sec1.72.84.1-1.81.61.61.61.6-1.41.6-1.7-1.7-2.0
Patch foraging water rate 12 sec3.35.15.9-2.42.22.32.32.3-2.22.3-2.4-2.3-1.9
Patch foraging water rate 18 sec0.20.30.4-0.60.60.50.50.6-0.60.5-0.5-0.5-0.2
Patch foraging water rate 24 sec0.00.00.1-0.20.20.10.20.2-0.10.1-0.2-0.2-0.3
Patch foraging water rate 6 sec0.10.20.5-0.40.20.20.30.4-0.00.3-0.6-0.6-0.7
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.20.20.10.1-0.0-0.20.1-0.0-0.1-0.1
Distance traveled before self-admin0.00.10.1-0.20.30.30.30.1-0.20.3-0.2-0.2-0.1
Distance traveled after self-admin1.21.32.1-1.01.21.21.11.1-1.21.2-0.9-0.9-1.5
Extensor digitorum longus weight0.62.32.51.6-1.5-1.5-1.5-1.51.5-1.51.61.61.3
Bone: elastic displacement0.80.91.60.8-0.9-0.9-1.0-0.90.8-1.01.01.01.3
Bone: elastic work1.21.62.21.2-1.2-1.2-1.3-1.21.2-1.31.21.21.5
Bone: endosteal estimation0.61.41.5-1.21.11.21.21.1-1.21.2-1.2-1.2-1.1
Bone: endosteal perimeter1.53.03.5-1.91.81.81.71.6-1.81.8-1.7-1.7-1.6
Epididymis fat weight2.25.16.22.3-2.2-2.3-2.3-2.22.5-2.32.32.31.9
Delta time in closed arm before/after self-admin0.10.10.5-0.30.30.30.30.4-0.40.3-0.2-0.1-0.7
Delta time in open arm before/after self-admin1.51.41.9-1.41.21.21.21.2-1.21.2-1.2-1.3-0.6
Diff in mean of infusions in LGA sessions0.40.41.20.7-0.7-0.6-0.5-0.60.4-0.50.40.51.1
Delay discount exponential model param0.20.20.5-0.40.20.30.40.5-0.10.4-0.7-0.70.4
Extinction: sum of active levers before priming0.30.30.90.9-0.7-0.5-0.5-0.50.3-0.40.40.50.5
Active lever presses in extinction session 60.00.00.10.2-0.2-0.1-0.1-0.2-0.0-0.10.10.10.1
Bone: final force0.40.60.80.9-0.9-0.8-0.8-0.80.9-0.80.70.70.5
Bone: final moment0.00.00.10.2-0.2-0.2-0.2-0.20.2-0.20.00.00.0
Food consumed during 24 hour testing period0.20.20.50.7-0.4-0.4-0.4-0.50.2-0.30.50.50.2
Glucose0.00.00.2-0.1-0.1-0.1-0.00.10.2-0.1-0.2-0.10.5
Heart weight3.55.06.02.4-2.2-2.2-2.2-2.22.1-2.22.22.22.4
Delay discount hyperbolic model param0.30.30.7-0.60.40.50.60.6-0.30.5-0.8-0.80.3
Intermittent access intake day 1-15 change0.90.91.21.1-1.0-1.0-0.9-0.91.1-1.00.80.71.1
Intermittent access intake escalation0.80.81.11.1-0.9-0.9-0.8-0.81.0-0.80.70.61.0
Intermittent access intake escalation 21.01.01.51.2-1.1-1.0-0.9-1.01.1-0.90.70.71.1
Intermitt. access day 1 inactive lever presses1.31.41.7-1.31.21.21.21.1-1.21.2-1.3-1.3-0.9
Intermitt. access day 15 inactive lever presses0.80.91.00.9-1.0-0.9-0.9-0.91.0-0.90.90.80.9
Intermitt. access escalation Index0.70.61.0-0.70.70.80.80.7-1.00.9-0.9-0.8-0.6
Intermittent access day 1 total infusions0.00.00.1-0.20.0-0.1-0.1-0.00.1-0.20.20.20.0
Intermittent access day 15 total infusions0.40.50.80.7-0.7-0.7-0.7-0.50.8-0.70.60.60.9
Intermittent access terminal intake (last 3 days)0.10.10.10.2-0.3-0.3-0.3-0.10.3-0.30.20.20.3
Intermittent access total infusions0.20.30.60.3-0.5-0.5-0.5-0.40.6-0.60.40.40.8
Intermittent access day 1 locomotion0.20.20.5-0.70.50.50.50.6-0.60.4-0.5-0.40.1
Intermittent access day 15 total locomotion0.10.10.4-0.60.40.30.30.6-0.20.2-0.3-0.20.3
Intermittent access total locomotion0.10.20.4-0.50.20.20.30.5-0.20.2-0.5-0.50.6
Intermittent access standard deviation1.41.52.11.2-1.2-1.3-1.3-1.11.5-1.31.11.01.2
Left kidney weight0.41.11.81.3-1.2-1.1-1.1-1.01.0-1.01.01.00.7
Right kidney weight0.30.81.61.3-1.1-0.9-0.9-0.80.9-0.80.80.70.6
Cocaine induced anxiety0.10.10.20.3-0.2-0.3-0.3-0.30.4-0.30.30.3-0.4
Post-drug Anxiety1.01.11.61.3-1.1-1.1-1.1-1.11.1-1.01.11.10.4
Baseline Anxiety0.60.71.00.9-0.8-0.8-0.8-0.70.7-0.80.80.91.0
Tail length0.51.42.11.4-1.2-1.2-1.1-1.31.1-1.11.11.11.0
Length with tail0.31.21.61.3-1.1-1.1-1.1-1.11.1-1.11.11.10.7
Length without tail0.00.00.10.1-0.1-0.2-0.2-0.20.3-0.20.30.3-0.0
Times rat made contact with spout0.00.00.0-0.20.10.10.10.0-0.10.1-0.1-0.00.1
Lifetime Intake0.00.10.2-0.0-0.1-0.2-0.2-0.00.2-0.30.20.20.5
Liver weight, left1.82.93.31.8-1.6-1.7-1.7-1.71.7-1.71.81.81.4
Liver weight, right6.310.412.33.5-3.3-3.3-3.3-3.23.3-3.33.23.22.9
Locomotor activity0.00.00.1-0.40.30.10.10.20.10.00.10.30.1
Locomotor testing distance1.72.83.5-1.91.71.71.71.8-1.51.6-1.6-1.5-1.9
Locomotor testing rearing0.00.00.2-0.20.10.00.00.10.1-0.00.00.20.4
Locomotion in novel chamber1.01.32.1-1.00.91.21.21.1-1.21.3-1.4-1.4-0.3
Locomotion in novel chamber post-restriction0.10.21.10.2-0.2-0.3-0.3-0.40.3-0.30.30.21.0
Fecal boli incidents, locomotor time 10.10.10.50.1-0.1-0.0-0.00.00.1-0.0-0.1-0.10.7
Change in fecal boli incidents, locomotor task0.10.10.30.2-0.2-0.3-0.3-0.40.1-0.30.50.5-0.4
Time >=10cm from walls, locomotor time 10.30.30.5-0.70.60.60.50.5-0.50.5-0.5-0.4-0.6
Bouts of movement, locomotor time 10.10.10.2-0.50.40.30.30.3-0.40.3-0.3-0.2-0.4
Total resting periods, locomotor time 10.20.20.4-0.50.40.40.40.3-0.50.4-0.3-0.3-0.6
Rest time, locomotor task time 10.10.10.2-0.30.20.30.30.4-0.40.3-0.3-0.4-0.3
Distance moved, locomotor task time 10.40.40.90.6-0.5-0.5-0.6-0.70.5-0.50.60.70.9
Vertical activity count, locomotor time 10.00.00.1-0.20.00.10.20.1-0.00.2-0.3-0.20.3
Time >=10cm from walls, locomotor time 22.42.62.91.6-1.6-1.6-1.6-1.71.5-1.61.61.61.6
Bouts of movement, locomotor time 21.01.02.9-1.31.10.90.80.8-0.90.8-0.7-0.7-1.7
Total resting periods, locomotor time 21.11.23.4-1.31.21.00.90.9-1.00.9-0.8-0.8-1.9
Rest time, locomotor task time 21.01.21.5-1.00.91.01.01.1-1.21.0-1.1-1.2-1.2
Distance moved, locomotor task time 22.63.05.61.8-1.8-1.6-1.6-1.71.7-1.61.41.52.4
Vertical activity count, locomotor time 20.91.03.40.9-1.0-0.9-0.8-0.91.1-0.90.60.71.8
Light reinforcement 10.30.60.90.8-0.6-0.7-0.8-0.90.7-0.81.00.90.4
Light reinforcement 20.40.50.70.8-0.7-0.7-0.7-0.70.8-0.70.70.50.5
Bone: marrow area0.61.21.4-1.11.01.11.11.0-1.11.1-1.2-1.2-1.1
Bone: maximum diameter0.71.21.5-1.21.21.11.11.0-1.11.1-1.0-1.0-1.2
Bone: maximum force0.10.20.20.4-0.4-0.4-0.4-0.40.5-0.40.30.30.5
Bone: maximum moment0.10.10.2-0.40.30.30.30.3-0.20.3-0.4-0.4-0.1
Mean time between licks in bursts5.98.310.03.2-2.8-2.9-2.9-2.82.9-2.93.03.12.1
Mean num. licks in bursts0.00.00.1-0.20.20.10.10.20.20.00.10.2-0.1
Cd content in liver1.31.42.0-1.41.21.21.21.2-1.21.1-1.2-1.2-0.7
Co content in liver0.10.20.20.4-0.5-0.4-0.4-0.40.5-0.40.30.30.1
Cu content in liver0.30.40.50.7-0.6-0.6-0.6-0.60.7-0.60.60.60.2
Fe content in liver0.81.01.4-1.21.11.01.01.0-0.90.9-0.9-0.9-1.0
K content in liver1.01.01.51.2-1.1-1.0-1.0-0.91.0-1.00.80.80.8
Mg content in liver0.40.40.7-0.50.50.60.70.6-0.70.7-0.8-0.8-0.4
Mn content in liver0.10.10.20.4-0.3-0.3-0.3-0.20.2-0.30.20.10.5
Na content in liver3.23.44.22.0-1.8-1.8-1.8-1.81.8-1.81.91.91.8
Rb content in liver0.60.81.01.0-1.0-0.9-0.9-1.00.9-0.90.80.80.8
Se content in liver1.11.31.5-1.01.11.11.11.2-1.21.2-1.2-1.2-1.2
Sr content in liver0.10.10.1-0.20.20.20.20.2-0.20.3-0.2-0.2-0.3
Zn content in liver0.70.81.0-0.90.80.90.90.9-0.90.9-1.0-1.0-0.5
Bone: minimum diameter1.73.24.1-2.01.81.81.81.7-1.71.8-1.7-1.8-1.6
Time in familiar zone, hab. session 12.82.63.11.8-1.6-1.6-1.6-1.61.6-1.61.61.61.4
Time in novel zone, hab. session 17.16.98.2-2.92.62.62.62.7-2.62.6-2.7-2.7-2.3
Total zone transitions, hab. session 11.31.82.31.5-1.3-1.3-1.4-1.41.3-1.31.51.50.9
Total locomotion distance, hab. session 10.10.10.30.6-0.4-0.3-0.3-0.30.3-0.20.30.3-0.3
Locomotion velocity, hab. session 10.10.20.40.6-0.5-0.4-0.4-0.40.4-0.30.30.4-0.1
Time in familiar zone, hab. session 20.70.71.10.8-0.8-0.8-0.8-1.00.7-0.80.80.81.0
Time in novel zone, hab. session 21.21.21.4-1.11.01.01.01.2-0.91.0-1.1-1.1-1.2
Total zone transitions, hab. session 24.86.38.72.9-2.7-2.6-2.5-2.52.6-2.52.42.41.9
Total locomotion distance, hab. session 22.33.14.92.2-2.1-1.9-1.8-1.71.9-1.71.51.51.2
Locomotion velocity, hab. session 21.92.64.42.1-1.9-1.7-1.6-1.51.7-1.61.41.40.9
Novel to familiar place preference ratio1.01.11.6-1.31.01.01.01.0-1.11.0-1.1-1.1-0.2
Novelty place preference0.60.71.1-1.00.80.80.80.8-0.90.8-0.9-0.90.1
Time in novel zone, NPP test0.90.91.4-1.20.90.91.01.0-1.00.9-1.1-1.1-0.0
Total zone transitions, NPP test1.72.42.81.7-1.6-1.6-1.6-1.61.7-1.61.51.51.1
Total locomotion distance, NPP test0.30.40.70.8-0.8-0.7-0.6-0.50.9-0.60.30.30.2
Locomotion velocity, NPP test0.30.50.80.8-0.8-0.7-0.7-0.70.9-0.70.60.60.2
Intraocular pressure0.00.00.1-0.30.20.20.10.0-0.10.10.0-0.0-0.4
Delta distance traveled before/after self-admin1.61.72.3-1.51.41.31.21.3-1.31.2-1.1-1.2-1.5
Delta ambulatory time before/after self-admin1.21.32.7-1.21.21.11.01.2-1.21.1-0.9-1.0-1.6
Parametrial fat weight4.38.39.8-3.12.82.92.92.9-2.82.9-3.1-3.1-2.4
Pavlov. Cond. lever latency0.50.61.31.1-1.0-0.8-0.7-0.80.7-0.70.50.50.6
Pavlov. Cond. magazine entry latency0.40.61.10.5-0.5-0.6-0.7-0.70.6-0.80.90.91.0
Pavlov. Cond. change in total contacts0.40.50.8-0.90.80.70.70.7-0.70.6-0.6-0.5-0.4
Pavlov. Cond. index score0.00.10.3-0.50.40.20.10.2-0.10.00.10.10.2
Pavlov. Cond. latency score0.10.10.3-0.60.40.20.20.3-0.20.10.00.00.2
Pavlov. Cond. lever contacts0.10.10.3-0.50.50.30.20.3-0.20.20.00.1-0.3
Pavlov. Cond. magazine entry number0.60.71.1-0.60.60.80.90.8-0.80.9-1.0-1.0-1.1
Pavlov. Cond. intertrial magazine entries0.50.60.80.8-0.7-0.8-0.8-0.80.8-0.80.90.90.7
Pavlov. Cond. lever-magazine prob. diff.0.00.10.2-0.50.40.20.10.2-0.20.00.10.10.3
Pavlov. Cond. response bias0.10.20.40.1-0.1-0.3-0.4-0.30.3-0.40.60.70.5
Pavlov. Cond. lever latency1.11.52.31.5-1.3-1.3-1.2-1.31.2-1.21.11.11.0
Pavlov. Cond. magazine entry latency1.61.82.4-1.51.51.41.41.4-1.51.4-1.2-1.1-1.1
Pavlov. Cond. change in total contacts2.12.93.4-1.81.81.71.71.8-1.71.7-1.6-1.5-1.7
Pavlov. Cond. index score1.72.22.9-1.71.61.61.51.6-1.51.5-1.3-1.3-1.3
Pavlov. Cond. latency score1.41.72.2-1.51.41.31.31.4-1.31.3-1.2-1.1-1.1
Pavlov. Cond. lever contacts2.33.14.0-2.01.91.81.81.8-1.81.7-1.6-1.5-1.6
Pavlov. Cond. magazine entry number0.50.60.91.0-1.0-0.9-0.8-0.80.9-0.80.50.50.5
Pavlov. Cond. intertrial magazine entries1.41.82.21.5-1.4-1.4-1.4-1.31.5-1.41.31.31.2
Pavlov. Cond. lever-magazine prob. diff.1.72.12.8-1.71.61.51.51.6-1.51.4-1.3-1.2-1.2
Pavlov. Cond. response bias1.82.53.3-1.81.71.61.61.6-1.61.6-1.4-1.3-1.5
Time in closed arm before self-admin0.00.00.10.2-0.2-0.2-0.2-0.10.2-0.20.20.3-0.1
Time in closed arm after self-admin0.10.10.50.1-0.1-0.1-0.10.10.2-0.10.10.3-0.7
Time in open arm before self-admin0.10.10.3-0.40.30.40.40.3-0.30.3-0.5-0.6-0.3
Time in open arm after self-admin2.93.24.0-2.01.81.81.81.7-1.81.8-1.9-2.0-1.0
Bone: periosteal estimation0.71.41.7-1.31.11.21.21.1-1.11.2-1.2-1.2-1.1
Bone: periosteal perimeter0.71.11.6-1.31.21.11.01.0-1.01.0-1.0-1.0-0.9
Bone: post-yield work1.42.02.5-1.41.31.41.41.3-1.41.4-1.6-1.6-1.2
Progressive ratio test 1 active lever presses3.43.64.21.7-1.7-1.9-2.0-1.82.0-2.02.12.11.7
Progressive ratio test 1 breakpoint4.34.55.21.9-2.0-2.1-2.2-2.02.2-2.32.22.32.0
Progressive ratio test 1 inactive lever presses1.11.21.70.9-0.9-1.1-1.2-1.11.2-1.21.31.30.8
Progressive ratio test 2 active lever presses0.10.10.60.1-0.3-0.3-0.3-0.10.2-0.40.30.30.8
Progressive ratio test 2 breakpoint0.20.20.60.2-0.4-0.4-0.4-0.20.4-0.50.40.30.8
Progressive ratio test 2 inactive lever presses0.00.00.1-0.30.20.0-0.00.10.0-0.10.20.1-0.1
Incentive Sensitization - Responses0.20.20.4-0.60.40.40.50.6-0.50.4-0.5-0.60.2
Incentive Sensitization - Breakpoint0.30.30.5-0.60.50.50.60.7-0.60.6-0.6-0.70.1
Sum of active levers in priming session hrs 5-61.81.72.61.6-1.4-1.3-1.3-1.41.2-1.21.21.21.1
Progressive ratio0.30.30.50.6-0.6-0.6-0.6-0.50.4-0.60.50.40.7
Food seeking constrained by brief footshock4.85.96.52.4-2.4-2.5-2.5-2.52.4-2.52.42.42.2
Seeking ratio, punishment vs. effort1.01.21.41.1-1.0-1.1-1.1-1.21.2-1.11.11.10.8
Retroperitoneal fat weight0.20.81.00.9-0.8-0.9-0.9-0.91.0-1.01.01.00.4
Reaction time number correct0.10.21.0-0.20.20.20.20.50.00.2-0.4-0.2-1.0
Reaction time mean minus median0.50.71.2-1.11.00.90.91.0-0.90.8-0.7-0.50.2
Reaction time mean minus median AUC0.10.20.3-0.50.50.40.40.5-0.40.3-0.3-0.10.5
Reaction time num false alarms0.40.50.8-0.70.70.60.60.7-0.60.6-0.7-0.8-0.9
Reaction time num false alarms AUC0.91.31.7-1.21.11.11.11.1-1.11.1-1.1-1.2-1.3
Reaction time trials correct on left0.10.21.0-0.20.20.20.20.50.00.2-0.4-0.2-1.0
Reaction time trials on left0.10.21.0-0.30.20.30.30.6-0.00.3-0.4-0.3-1.0
Reaction time mean0.60.81.1-1.01.01.01.01.0-1.11.0-0.8-0.7-0.2
Reaction time mean AUC0.30.40.5-0.70.70.70.70.7-0.70.6-0.5-0.40.1
Median of all reaction times0.50.71.0-0.90.90.90.90.9-1.00.9-0.8-0.8-0.4
Reaction time omissions0.30.40.6-0.80.70.70.70.7-0.70.6-0.7-0.70.1
Reaction time false alarm rate0.91.31.5-1.21.21.21.11.0-1.21.1-1.0-1.2-1.0
Reaction time premature initiation rate0.20.30.50.7-0.5-0.5-0.5-0.50.4-0.50.60.70.1
Reaction time premature initiations0.20.30.60.8-0.6-0.5-0.5-0.40.6-0.50.50.8-0.2
Std. dev. reaction times1.82.63.6-1.91.81.71.71.7-1.71.6-1.5-1.4-0.6
Reaction time trials completed0.10.21.0-0.30.20.30.30.6-0.00.3-0.4-0.3-1.0
Reaction time trials AUC0.10.21.0-0.30.20.30.30.6-0.00.3-0.4-0.3-1.0
Run reversals in cocaine runway, females0.00.00.0-0.10.10.00.00.00.1-0.00.10.20.2
Run reversals in cocaine runway, males0.60.60.8-0.90.80.80.80.8-0.80.8-0.7-0.7-0.7
Latency to leave start box in cocaine runway0.40.51.10.7-0.7-0.7-0.7-0.61.0-0.70.70.70.2
Latency to leave start box in cocaine runway, F0.10.10.60.2-0.3-0.3-0.3-0.20.8-0.30.30.4-0.1
Latency to leave start box in cocaine runway, M0.40.40.90.9-0.7-0.7-0.7-0.60.6-0.60.60.50.3
Std. dev. time between licks in bursts0.00.00.00.1-0.00.00.0-0.0-0.10.0-0.1-0.0-0.1
Total sessions with >9 infusions1.21.32.01.0-1.0-1.1-1.1-0.91.0-1.21.21.31.4
Short access day 1 total inactive lever presses0.20.20.5-0.70.50.50.40.3-0.50.4-0.4-0.4-0.0
Short access day 10 total inactive lever presses2.02.22.6-1.41.41.51.61.3-1.61.6-1.6-1.6-1.3
Short access day 1 total infusions0.00.10.3-0.30.10.10.10.1-0.20.1-0.2-0.20.6
Short access day 10 total infusions0.00.00.1-0.0-0.1-0.2-0.2-0.10.3-0.20.20.20.3
Short access total infusions0.00.00.1-0.30.20.10.10.2-0.00.0-0.1-0.00.2
Short access day 1 locomotion0.40.41.0-1.00.70.60.60.8-0.30.5-0.6-0.6-0.4
Short access day 10 total locomotion0.20.20.3-0.40.30.30.40.4-0.40.3-0.6-0.50.5
Short access total locomotion0.10.10.50.2-0.3-0.3-0.3-0.20.4-0.30.20.30.7
One hour access (0.3 mA shock)0.10.10.2-0.30.30.30.30.4-0.30.3-0.3-0.3-0.2
Compulsive drug intake5.05.16.0-2.32.32.32.32.1-2.32.3-2.1-2.1-2.4
One hour access (shock baseline)1.92.22.51.5-1.4-1.5-1.5-1.31.5-1.51.51.51.6
Social response proportion0.30.40.6-0.50.40.50.60.7-0.50.6-0.8-0.8-0.5
Social responses0.70.91.20.8-0.9-1.0-1.0-0.91.1-1.01.01.00.6
Social time0.10.10.6-0.1-0.1-0.2-0.2-0.10.2-0.30.40.40.7
Soleus weight0.10.30.40.7-0.6-0.5-0.5-0.50.5-0.50.50.50.5
Bone: stiffness0.10.10.20.4-0.4-0.4-0.4-0.40.4-0.40.30.30.4
Tibialis anterior weight8.127.933.2-5.85.35.35.35.3-5.25.3-5.2-5.2-4.8
Time to tail flick, vehicle, before self-admin2.22.22.8-1.61.51.51.51.4-1.61.5-1.4-1.3-1.7
Time to tail flick, vehicle, after self-admin1.61.72.0-1.41.21.31.31.3-1.11.3-1.4-1.4-1.4
Time to tail flick, test, before self-admin0.20.20.3-0.30.30.40.40.4-0.40.4-0.4-0.4-0.5
Time to tail flick, test, after self-admin0.20.21.2-0.30.30.30.30.4-0.20.3-0.3-0.2-1.1
Delta time to tail flick, vehicle, before/after SA0.50.50.80.9-0.9-0.7-0.6-0.60.8-0.60.50.50.8
Delta time to tail flick, test, before/after SA0.40.40.9-0.70.70.50.50.6-0.50.5-0.4-0.4-1.0
Tibia length2.36.67.92.8-2.6-2.6-2.6-2.62.6-2.62.52.52.2
Ambulatory time before self-admin0.10.10.20.3-0.1-0.1-0.1-0.30.2-0.10.20.20.4
Ambulatory time after self-admin1.21.32.4-1.11.31.21.11.1-1.21.1-0.8-0.8-1.6
Bone: tissue strength0.60.50.6-0.80.80.70.70.6-0.70.7-0.8-0.8-0.6
Total heroin consumption1.21.42.31.5-1.4-1.2-1.1-1.31.0-1.10.90.91.2
Bone: trabecular number0.00.00.10.1-0.1-0.2-0.2-0.20.3-0.20.20.20.1
Bone: trabecular spacing0.00.00.10.3-0.2-0.2-0.2-0.20.2-0.20.20.10.1
Bone: trabecular thickness0.10.10.30.2-0.3-0.3-0.3-0.30.3-0.30.20.20.6
Bone: trabecular tissue density16.723.627.25.2-4.9-4.9-4.9-5.04.8-4.84.84.84.5
Water consumed over 24 hours0.10.20.3-0.30.40.40.40.3-0.50.5-0.5-0.5-0.4
Number of responses in last shaping day0.00.00.1-0.20.1-0.0-0.1-0.10.1-0.10.30.3-0.1