Hub : Genes

Kat5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL mRNA stability Kat5 0.25 0.15 5.9e-04 0.16 0.09 0.08 0.1 1.1e-04 3.6e-03 7.0e-03 2.2e-03
2 PL gene expression Kat5 0.06 0.04 6.9e-07 0.06 0.06 0.04 0.05 1.2e-06 2.9e-07 2.5e-05 2.6e-06
3 OFC gene expression Kat5 0.26 0.14 1.5e-03 0.1 0.06 0.04 0.06 2.1e-03 1.8e-02 5.0e-02 1.3e-02
4 Brain gene expression Kat5 0.16 0.09 1.5e-08 0.09 0.07 0.07 0.09 2.3e-08 2.8e-07 1.7e-07 2.6e-08
5 BLA gene expression Kat5 0.12 0.1 7.2e-04 0.04 0.04 0.04 0.05 2.2e-03 4.1e-03 5.4e-03 1.3e-03
6 NAcc gene expression Kat5 0.03 0.02 1.7e-03 0.02 0.02 0.02 0.02 7.9e-04 3.3e-03 4.1e-03 3.8e-03
7 RMTg isoform ratio NM_001005872.1 0.51 0.17 7.5e-03 0 -0.01 0.01 0.02 3.1e-01 9.5e-01 1.4e-01 1.1e-01
8 Eye alternative TSS XM_039092592.1 0.36 0.21 6.1e-03 -0.01 0.02 0.1 0.07 5.9e-01 1.6e-01 1.2e-02 3.3e-02
9 RMTg intron excision ratio chr1_202901729_202901819 0.13 0.08 5.3e-03 0.03 0.04 -0 0.03 5.9e-02 2.5e-02 3.3e-01 6.6e-02
10 RMTg intron excision ratio chr1_202901729_202902261 0.42 0.19 4.7e-03 0.02 0.01 0.07 0.07 9.0e-02 1.4e-01 7.3e-03 6.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.81.44.30.80.6-1.3-0.91.3-1.31.3-0.7-2.10.4
Area under the delay curve0.80.81.6-0.30.8-1.3-1.01.1-1.3-0.5-0.2-1.00.8
BMI with tail1.75.620.62.80.4-0.8-1.01.1-0.93.0-3.2-4.52.2
BMI without tail0.71.56.01.30.3-0.6-1.10.6-0.61.0-1.2-2.41.6
Body weight1.14.516.94.1-2.32.11.6-1.92.02.3-0.5-1.60.5
Weight adjusted by age1.71.93.31.8-1.61.81.4-1.61.81.2-0.00.4-1.0
Bone surface1.52.710.62.8-1.20.41.0-0.30.33.31.0-1.6-1.2
Bone volume0.91.68.21.6-0.2-0.40.10.5-0.42.90.2-1.7-1.1
Breakpoint value in progressive ratio session1.92.14.62.1-1.61.71.6-1.51.71.4-0.10.1-1.3
Number of licking bursts0.10.20.40.7-0.40.40.5-0.30.40.50.0-0.1-0.5
Context. condit. distance diff. score1.21.53.5-1.71.5-1.3-1.91.2-1.2-0.6-0.7-0.40.9
Locomotion velocity, session 10.20.20.40.1-0.30.30.1-0.60.4-0.60.50.40.6
Locomotion distance, session 10.50.72.20.90.2-0.7-0.70.4-0.60.2-0.9-1.51.3
Locomotion velocity, session 20.81.04.02.0-1.00.90.7-0.80.90.9-0.5-0.90.3
Locomotion distance, session 20.50.61.91.1-0.1-0.1-0.10.2-0.30.0-1.4-1.21.3
Locomotion velocity, session 31.11.35.0-0.21.1-0.8-0.80.8-0.70.3-2.2-1.41.4
Locomotion distance, session 30.10.10.3-0.10.2-0.1-0.10.1-0.1-0.0-0.6-0.20.4
Stereotopy head waving bouts, day 31.61.94.5-1.11.5-1.5-1.41.4-1.5-0.2-1.1-1.52.1
Stereotopy head waving duration, day 31.11.32.2-1.31.3-1.5-1.31.3-1.4-0.2-0.0-0.91.2
Locomotion velocity, session 72.62.810.9-0.41.7-1.3-1.51.5-1.30.9-3.3-2.01.2
Locomotion distance, session 71.01.25.6-0.00.8-0.7-0.70.6-0.6-0.3-2.4-1.21.7
Stereotopy head waving bouts, day 70.50.61.4-0.50.8-0.8-0.61.0-0.91.20.1-0.8-0.5
Stereotopy head waving duration, day 70.40.52.30.9-0.2-0.30.10.3-0.31.50.7-1.0-0.7
Locomotion velocity, session 80.70.81.41.2-1.21.01.0-1.10.8-0.70.50.50.8
Locomotion distance, session 80.71.12.8-0.51.1-0.7-1.20.8-0.70.5-1.7-1.21.2
Degree of sensitization distance0.80.82.80.00.8-0.7-0.70.7-0.60.2-1.7-1.21.2
Degree of sensitization stereotypy0.40.52.40.7-0.20.10.40.10.11.50.4-0.5-1.2
Conditioned locomotion1.01.22.81.5-1.31.70.9-1.41.40.30.30.3-0.0
Cocaine response after cond. corrected1.21.32.7-1.41.2-1.0-1.10.8-0.9-1.5-1.2-0.21.6
Cocaine response after cond. not corrected1.01.12.3-1.21.1-1.1-1.00.9-1.0-1.1-0.8-0.31.5
Cocaine response before conditioning0.50.61.60.9-0.80.50.9-0.40.41.20.70.0-1.0
Saline control response1.41.86.12.5-2.01.11.5-1.41.10.41.0-0.10.4
Bone: connectivity density0.71.14.02.0-0.4-0.5-0.10.4-0.61.60.1-1.90.1
Bone: cortical apparent density0.20.30.50.6-0.70.50.5-0.50.5-0.60.20.5-0.3
Bone: cortical area0.81.22.01.3-0.91.41.2-1.11.41.3-0.70.2-0.9
Bone: cortical porosity0.30.30.80.20.3-0.7-0.90.6-0.70.3-0.2-0.90.2
Bone: cortical porosity0.10.20.50.6-0.3-0.3-0.40.2-0.40.40.3-0.70.0
Bone: cortical thickness2.94.78.92.5-2.63.02.4-2.83.0-0.40.01.5-0.6
Bone: cortical thickness1.41.62.41.0-1.41.51.5-1.61.5-1.50.31.20.4
Bone: cortical tissue density0.30.40.80.6-0.90.60.7-0.60.6-0.60.40.6-0.4
Condit. Reinf. active minus inactive responses0.20.31.90.5-0.1-0.0-0.1-0.10.2-0.0-1.4-0.40.3
Condit. Reinf. active-inactive response ratio0.00.00.10.2-0.2-0.1-0.1-0.10.1-0.3-0.30.1-0.2
Condit. Reinf. active responses0.50.64.90.40.30.1-0.30.10.20.6-2.2-0.70.3
Condit. Reinf. inactive responses0.70.84.2-0.00.8-0.2-0.60.5-0.11.1-2.1-1.10.4
Incentive salience index mean0.40.53.30.70.1-0.0-0.30.00.20.4-1.8-1.00.6
Condit. Reinf. lever presses0.30.41.40.7-0.00.50.1-0.40.71.2-1.1-0.70.0
Condit. Reinf. active minus inactive responses0.30.41.2-0.30.6-0.7-0.30.6-0.61.1-0.5-0.5-0.7
Condit. Reinf. active-inactive response ratio1.01.13.5-0.71.2-0.6-0.60.8-0.51.9-1.6-0.8-0.7
Condit. Reinf. active responses0.30.41.00.20.2-1.0-0.50.7-0.80.60.1-0.7-0.4
Condit. Reinf. inactive responses0.50.61.20.6-0.2-1.0-0.60.6-1.0-0.81.1-0.60.6
Condit. Reinf. lever presses1.21.74.32.1-1.20.91.2-0.91.02.00.4-0.3-1.6
Condit. Reinf. lever reinforcers received0.20.30.70.6-0.2-0.6-0.20.4-0.50.80.4-0.5-0.7
Conditioned reinforcement - actives0.40.42.3-0.30.10.00.1-0.10.21.30.40.5-1.5
Conditioned reinforcement - inactives2.02.36.7-2.61.9-1.4-1.51.7-1.50.4-0.50.6-1.5
Conditioned locomotion2.12.510.5-3.22.0-1.4-1.51.5-1.3-0.6-0.01.0-0.8
Patch foraging indifference point 0 sec0.10.10.3-0.20.3-0.5-0.30.3-0.3-0.00.3-0.20.1
Patch foraging indifference point AUC2.42.85.02.2-2.01.72.0-1.71.71.31.30.4-1.7
Delay disc. indifference point, 0s delay1.61.73.1-1.01.3-1.7-1.61.4-1.7-0.80.1-1.21.5
Delay disc. indifference point, 16s delay1.11.12.0-0.91.2-1.2-1.11.4-1.2-0.1-1.4-0.70.0
Delay disc. indifference point, 2s delay0.20.20.4-0.40.6-0.6-0.50.6-0.60.1-0.4-0.60.4
Delay disc. indifference point, 24s delay0.30.31.7-0.3-0.0-0.2-0.2-0.1-0.2-1.30.30.30.7
Delay disc. indifference point, 4s delay1.01.02.3-0.50.7-1.2-1.01.0-1.2-1.20.0-0.81.5
Delay disc. indifference point, 8s delay0.50.61.0-0.30.4-1.0-0.80.7-1.0-0.90.2-0.61.0
Indifference point function ln k4.86.714.2-3.83.0-2.2-2.82.2-2.2-2.7-2.6-0.22.8
Indifference point function log k4.86.714.2-3.83.0-2.2-2.82.2-2.2-2.7-2.6-0.22.8
Patch foraging total patch changes 0 sec0.00.10.3-0.2-0.1-0.1-0.0-0.10.1-0.50.50.20.3
Patch foraging total patch changes 12 sec1.92.58.32.9-2.01.31.6-1.51.61.20.9-0.2-1.0
Patch foraging total patch changes 18 sec0.20.31.10.9-0.40.10.3-0.20.31.00.4-0.5-0.5
Patch foraging total patch changes 24 sec1.82.34.22.0-1.91.31.8-1.71.60.51.60.7-0.8
Patch foraging total patch changes 6 sec0.30.52.41.6-0.80.30.8-0.50.40.1-0.5-0.50.4
Patch foraging time to switch 0 sec0.91.34.81.7-0.0-0.1-0.40.4-0.22.2-1.0-2.1-0.2
Patch foraging water rate 0 sec1.01.67.1-2.70.9-0.2-0.30.1-0.1-1.80.52.0-0.1
Patch foraging water rate 12 sec2.84.315.2-3.91.6-1.3-1.30.9-1.3-3.60.32.11.5
Patch foraging water rate 18 sec1.31.84.4-2.01.3-1.0-1.10.8-0.9-2.1-0.70.61.7
Patch foraging water rate 24 sec1.11.66.7-2.61.2-0.5-0.90.4-0.6-1.9-0.21.30.9
Patch foraging water rate 6 sec1.32.07.3-2.41.0-0.4-0.50.2-0.4-2.7-0.71.41.6
Seeking ratio, delayed vs. immediate footshock0.50.51.0-0.10.6-0.8-0.70.9-0.8-0.3-1.0-0.80.7
Distance traveled before self-admin0.60.62.00.6-0.60.60.5-0.40.51.40.9-0.1-1.2
Distance traveled after self-admin0.30.41.10.4-0.50.50.5-0.40.50.60.90.2-1.0
Extensor digitorum longus weight2.911.535.56.0-4.13.93.3-3.73.82.70.9-0.7-0.7
Bone: elastic displacement0.91.05.1-1.0-0.10.50.2-0.60.4-2.3-0.31.50.9
Bone: elastic work1.11.42.41.1-1.41.51.2-1.51.4-1.40.11.00.8
Bone: endosteal estimation1.83.85.6-1.42.4-2.1-2.02.3-2.21.7-1.8-2.20.9
Bone: endosteal perimeter2.14.36.3-1.52.4-2.3-2.22.5-2.42.4-1.3-2.20.1
Epididymis fat weight1.63.87.9-2.82.7-2.3-2.22.4-2.30.4-0.5-1.00.5
Delta time in closed arm before/after self-admin0.80.83.50.2-0.20.2-0.2-0.40.1-1.8-0.80.01.9
Delta time in open arm before/after self-admin0.80.84.00.2-0.40.40.8-0.30.51.21.10.5-2.0
Diff in mean of infusions in LGA sessions0.60.71.10.8-1.01.01.1-1.01.00.20.30.8-0.8
Delay discount exponential model param0.60.61.10.3-0.61.10.9-0.91.10.50.10.8-0.7
Extinction: sum of active levers before priming1.51.55.22.3-1.31.31.0-1.01.21.4-0.4-0.7-0.5
Active lever presses in extinction session 63.43.34.91.7-1.92.22.1-2.12.21.60.81.1-1.9
Bone: final force1.11.85.52.3-1.51.41.2-1.31.41.80.3-0.5-0.5
Bone: final moment1.01.64.82.2-1.41.31.1-1.21.31.70.4-0.5-0.5
Food consumed during 24 hour testing period0.80.93.10.2-0.70.81.0-0.70.70.41.71.1-1.4
Glucose2.63.96.5-1.92.4-2.6-2.42.4-2.40.4-0.8-1.81.2
Heart weight2.33.25.7-2.42.2-2.2-1.72.0-2.1-1.2-1.2-0.71.5
Delay discount hyperbolic model param0.50.51.00.2-0.51.00.8-0.81.00.50.00.8-0.7
Intermittent access intake day 1-15 change0.50.52.2-0.6-0.00.60.2-0.40.60.6-0.21.2-1.5
Intermittent access intake escalation0.30.31.3-0.60.20.3-0.1-0.10.30.6-0.50.7-1.2
Intermittent access intake escalation 20.70.72.6-0.4-0.40.80.5-0.60.80.60.61.2-1.6
Intermitt. access day 1 inactive lever presses1.01.13.0-1.71.4-0.9-1.21.3-1.1-0.1-0.6-0.0-0.3
Intermitt. access day 15 inactive lever presses1.01.11.8-1.31.3-0.8-1.01.0-0.70.8-1.30.1-1.2
Intermitt. access escalation Index4.23.75.3-1.82.1-2.3-2.22.2-2.2-1.4-1.4-1.22.0
Intermittent access day 1 total infusions7.08.213.7-2.43.5-3.7-3.43.7-3.60.7-2.0-2.50.9
Intermittent access day 15 total infusions4.55.09.2-2.83.0-2.6-2.62.8-2.50.8-2.0-0.8-0.5
Intermittent access terminal intake (last 3 days)4.04.47.7-2.32.8-2.4-2.42.5-2.31.5-2.0-1.1-0.7
Intermittent access total infusions4.95.48.6-1.92.9-2.8-2.82.9-2.71.3-2.3-1.8-0.1
Intermittent access day 1 locomotion6.26.510.8-1.83.0-3.3-3.13.1-3.0-0.1-2.2-2.41.8
Intermittent access day 15 total locomotion3.03.25.8-2.12.4-2.2-2.22.2-2.00.8-1.5-0.8-0.5
Intermittent access total locomotion6.97.812.7-2.53.6-3.4-3.43.5-3.31.5-2.4-2.20.2
Intermittent access standard deviation0.30.41.1-1.00.6-0.3-0.60.3-0.20.4-0.00.6-1.1
Left kidney weight0.20.62.1-1.51.2-0.1-0.90.6-0.20.5-1.10.0-0.4
Right kidney weight0.30.72.4-0.50.11.00.5-0.61.11.2-0.10.8-1.5
Cocaine induced anxiety0.20.20.9-0.1-0.10.40.3-0.20.31.00.30.2-0.8
Post-drug Anxiety2.02.23.81.1-1.41.81.9-1.61.61.71.00.8-1.4
Baseline Anxiety1.92.03.61.8-1.81.71.8-1.91.90.10.10.6-0.0
Tail length1.44.37.41.3-2.42.52.0-2.72.5-1.12.22.2-0.7
Length with tail1.97.011.43.0-3.33.43.1-3.43.30.31.81.6-1.0
Length without tail1.53.37.42.7-2.32.22.4-2.12.11.00.30.4-0.5
Times rat made contact with spout0.10.20.50.7-0.5-0.1-0.1-0.1-0.1-0.60.5-0.20.3
Lifetime Intake4.85.48.5-1.82.9-2.9-2.92.9-2.70.9-2.3-1.90.5
Liver weight, left0.00.10.2-0.40.3-0.0-0.20.2-0.20.2-0.3-0.20.2
Liver weight, right0.10.21.6-0.30.3-0.1-0.20.1-0.4-0.4-0.5-0.21.2
Locomotor activity0.81.26.0-1.60.6-0.3-0.30.1-0.3-2.5-0.01.21.3
Locomotor testing distance1.32.210.7-2.00.7-0.7-0.50.3-0.7-3.30.31.31.9
Locomotor testing rearing1.62.56.6-1.91.0-1.7-1.31.2-1.7-2.61.60.61.5
Locomotion in novel chamber1.72.16.0-2.42.1-1.3-1.61.6-1.30.8-1.2-0.0-0.8
Locomotion in novel chamber post-restriction1.31.63.5-1.91.6-1.3-1.31.4-1.2-0.3-1.6-0.1-0.0
Fecal boli incidents, locomotor time 10.80.94.50.0-0.10.30.5-0.20.62.10.90.0-1.8
Change in fecal boli incidents, locomotor task1.01.04.50.00.3-0.6-0.60.3-0.6-1.3-1.1-0.72.1
Time >=10cm from walls, locomotor time 12.52.64.0-0.91.9-1.7-1.61.9-1.62.0-1.5-1.9-0.2
Bouts of movement, locomotor time 11.41.52.61.3-1.61.11.3-1.21.10.31.30.9-1.6
Total resting periods, locomotor time 10.91.02.61.1-1.20.81.0-0.80.80.61.20.6-1.6
Rest time, locomotor task time 10.30.31.8-1.30.6-0.2-0.30.3-0.3-0.20.30.6-0.4
Distance moved, locomotor task time 10.50.61.90.50.5-0.5-0.50.7-0.60.3-1.4-1.20.9
Vertical activity count, locomotor time 10.60.61.3-1.11.0-0.8-0.70.8-0.8-0.6-0.7-0.10.7
Time >=10cm from walls, locomotor time 20.30.41.50.00.10.0-0.00.10.01.10.9-0.2-1.2
Bouts of movement, locomotor time 20.20.30.70.8-0.70.30.5-0.20.2-0.10.70.2-0.7
Total resting periods, locomotor time 20.10.10.40.6-0.40.10.20.1-0.1-0.00.4-0.0-0.6
Rest time, locomotor task time 21.21.43.6-1.91.6-1.3-1.31.3-1.3-0.3-0.5-0.40.1
Distance moved, locomotor task time 20.80.91.91.4-1.21.21.1-1.11.10.20.30.4-0.2
Vertical activity count, locomotor time 21.01.12.30.1-0.91.11.1-1.21.1-1.50.21.40.6
Light reinforcement 10.20.42.0-0.6-0.0-0.5-0.00.1-0.3-0.91.40.6-0.0
Light reinforcement 20.40.61.8-1.20.7-0.1-0.20.4-0.11.20.00.4-1.3
Bone: marrow area1.94.05.9-1.52.4-2.1-2.12.3-2.21.6-1.9-2.31.1
Bone: maximum diameter0.50.94.90.5-0.30.70.7-0.50.82.2-0.20.0-1.3
Bone: maximum force1.22.18.22.6-0.90.80.6-0.50.82.9-0.5-1.7-0.6
Bone: maximum moment1.01.87.02.4-0.80.70.6-0.50.72.7-0.5-1.6-0.4
Mean time between licks in bursts0.60.82.30.8-1.00.40.7-0.90.5-1.50.60.41.4
Mean num. licks in bursts0.30.40.9-0.50.3-0.8-0.70.5-0.8-0.90.3-0.00.6
Cd content in liver0.50.52.0-1.20.5-0.1-0.10.3-0.10.40.70.9-1.4
Co content in liver1.21.48.0-1.40.0-0.10.0-0.1-0.2-2.81.01.60.7
Cu content in liver0.10.10.50.7-0.20.20.1-0.00.10.2-0.4-0.4-0.3
Fe content in liver0.20.20.80.4-0.40.50.9-0.50.60.60.00.2-0.2
K content in liver0.70.72.41.5-0.1-0.0-0.20.1-0.11.1-0.9-1.50.8
Mg content in liver1.61.74.50.41.0-1.5-1.31.5-1.60.7-0.9-2.11.0
Mn content in liver1.51.73.81.9-1.41.21.4-1.11.21.70.8-0.0-1.4
Na content in liver1.41.52.71.1-1.21.71.3-1.41.61.10.90.5-1.0
Rb content in liver2.02.44.7-1.31.7-2.1-1.72.1-2.2-0.6-0.5-1.21.0
Se content in liver0.50.63.20.20.3-0.4-0.20.6-0.51.8-0.0-0.5-1.4
Sr content in liver3.73.44.81.7-2.22.02.2-2.02.00.52.21.4-1.5
Zn content in liver0.30.41.51.2-0.70.60.7-0.50.60.5-0.1-0.3-0.2
Bone: minimum diameter2.34.36.3-1.12.3-2.2-2.32.5-2.41.3-2.3-2.50.9
Time in familiar zone, hab. session 10.60.51.2-0.40.8-0.8-0.70.8-0.70.2-1.1-0.80.5
Time in novel zone, hab. session 10.40.41.6-0.5-0.20.20.3-0.40.1-1.31.10.90.4
Total zone transitions, hab. session 10.30.41.51.2-0.60.50.3-0.50.60.5-0.8-0.4-0.2
Total locomotion distance, hab. session 10.50.82.1-0.71.1-0.6-1.00.8-0.50.4-1.5-1.00.6
Locomotion velocity, hab. session 10.20.41.3-0.20.7-0.3-0.60.4-0.20.4-1.1-0.80.5
Time in familiar zone, hab. session 20.50.52.1-0.0-0.40.30.2-0.50.2-1.50.30.61.3
Time in novel zone, hab. session 20.30.30.80.20.2-0.6-0.40.5-0.40.9-0.2-0.7-0.7
Total zone transitions, hab. session 21.01.34.81.30.2-1.1-0.91.0-1.31.0-0.5-2.21.0
Total locomotion distance, hab. session 21.41.84.0-0.21.2-1.4-1.41.4-1.40.4-1.4-2.01.6
Locomotion velocity, hab. session 21.52.04.2-0.41.4-1.5-1.51.5-1.50.7-1.6-2.11.3
Novel to familiar place preference ratio0.80.83.21.0-0.60.50.7-0.30.51.80.2-0.4-1.6
Novelty place preference0.50.52.20.6-0.30.10.40.00.11.50.4-0.4-1.5
Time in novel zone, NPP test0.40.41.60.5-0.20.00.30.10.01.30.4-0.3-1.2
Total zone transitions, NPP test0.50.73.41.8-0.90.40.1-0.50.41.20.4-1.0-0.0
Total locomotion distance, NPP test0.40.51.70.10.6-0.4-0.60.4-0.20.4-1.3-1.20.9
Locomotion velocity, NPP test0.30.41.60.20.4-0.2-0.50.3-0.10.4-1.3-1.00.6
Intraocular pressure0.81.14.4-1.20.10.30.5-0.20.40.91.51.3-2.1
Delta distance traveled before/after self-admin0.20.21.1-0.0-0.10.10.2-0.20.1-1.0-0.20.30.6
Delta ambulatory time before/after self-admin0.30.31.70.0-0.30.10.3-0.30.2-1.30.10.40.8
Parametrial fat weight2.65.08.7-2.63.0-2.6-2.52.8-2.50.8-1.6-2.00.8
Pavlov. Cond. lever latency0.10.10.6-0.50.00.0-0.10.0-0.1-0.8-0.10.7-0.2
Pavlov. Cond. magazine entry latency0.40.51.50.30.5-0.8-0.60.7-0.70.8-0.0-1.20.1
Pavlov. Cond. change in total contacts0.30.31.40.10.3-0.10.00.30.01.2-0.3-0.6-0.8
Pavlov. Cond. index score0.10.10.40.2-0.10.10.3-0.10.30.60.6-0.2-0.4
Pavlov. Cond. latency score0.10.10.30.10.1-0.2-0.00.1-0.00.50.4-0.5-0.0
Pavlov. Cond. lever contacts0.00.10.2-0.00.2-0.20.00.10.00.20.0-0.50.4
Pavlov. Cond. magazine entry number0.30.41.3-0.50.5-0.5-0.70.5-0.7-0.7-0.8-0.31.1
Pavlov. Cond. intertrial magazine entries0.20.31.2-0.40.20.20.1-0.10.4-0.1-1.10.7-0.9
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.5-0.20.20.4-0.20.40.70.5-0.4-0.4
Pavlov. Cond. response bias0.10.10.40.3-0.20.20.5-0.30.50.50.40.1-0.6
Pavlov. Cond. lever latency0.40.62.6-0.90.5-0.6-0.60.4-0.6-1.60.00.31.0
Pavlov. Cond. magazine entry latency1.11.35.72.4-1.30.81.1-0.91.01.1-0.3-0.6-0.6
Pavlov. Cond. change in total contacts1.31.86.71.8-0.90.81.0-0.50.82.6-0.5-0.6-2.0
Pavlov. Cond. index score1.31.64.32.1-1.11.11.1-0.81.12.0-0.5-0.6-1.4
Pavlov. Cond. latency score1.21.54.11.9-0.91.01.0-0.71.02.0-0.9-0.6-1.2
Pavlov. Cond. lever contacts0.71.01.90.9-0.91.01.1-0.90.91.30.70.4-1.4
Pavlov. Cond. magazine entry number2.42.910.2-3.22.1-1.4-1.81.4-1.5-1.7-0.10.51.4
Pavlov. Cond. intertrial magazine entries0.50.62.1-1.41.0-0.8-1.00.7-0.7-0.10.10.00.2
Pavlov. Cond. lever-magazine prob. diff.1.41.85.12.3-1.31.11.1-0.91.12.0-0.3-0.5-1.3
Pavlov. Cond. response bias1.11.53.21.8-1.31.01.4-1.01.11.60.8-0.0-1.5
Time in closed arm before self-admin0.30.31.9-0.00.1-0.20.30.2-0.11.40.5-0.3-0.9
Time in closed arm after self-admin0.40.52.1-0.10.4-0.2-0.30.2-0.2-0.6-1.5-0.51.2
Time in open arm before self-admin1.51.67.2-0.70.5-0.7-1.10.4-0.7-2.7-0.40.02.4
Time in open arm after self-admin0.40.52.3-0.4-0.30.10.3-0.20.1-1.01.51.0-0.3
Bone: periosteal estimation0.51.04.5-0.00.8-0.2-0.30.6-0.32.1-1.6-1.1-0.2
Bone: periosteal perimeter0.30.53.20.40.3-0.2-0.10.3-0.21.8-0.5-0.9-0.4
Bone: post-yield work4.56.116.20.61.9-2.0-2.02.5-2.14.0-2.5-4.0-0.1
Progressive ratio test 1 active lever presses1.51.62.9-1.61.6-1.7-1.71.6-1.5-0.0-0.4-0.3-0.4
Progressive ratio test 1 breakpoint1.21.22.2-1.51.4-1.5-1.51.3-1.3-0.1-0.2-0.1-0.5
Progressive ratio test 1 inactive lever presses1.01.11.8-1.11.2-1.3-1.41.2-1.3-0.8-0.6-0.30.4
Progressive ratio test 2 active lever presses2.32.54.3-1.82.1-1.9-2.01.9-1.70.8-1.2-0.5-0.8
Progressive ratio test 2 breakpoint2.02.24.8-2.22.0-1.8-1.91.7-1.50.2-1.00.0-0.8
Progressive ratio test 2 inactive lever presses5.15.89.9-3.13.1-3.1-2.93.1-3.00.6-1.1-0.8-0.7
Incentive Sensitization - Responses0.50.51.1-0.30.8-0.6-0.90.7-0.50.9-1.0-0.4-0.7
Incentive Sensitization - Breakpoint0.50.61.2-0.50.9-0.6-0.90.7-0.50.9-1.1-0.3-0.7
Sum of active levers in priming session hrs 5-65.14.99.21.5-2.02.72.3-2.42.72.10.71.8-3.0
Progressive ratio1.01.24.71.40.0-0.6-0.40.6-0.62.0-0.3-2.20.3
Food seeking constrained by brief footshock0.30.41.10.6-0.60.60.5-0.60.4-1.1-0.30.21.0
Seeking ratio, punishment vs. effort1.11.47.9-1.30.10.30.1-0.40.2-2.8-0.11.71.0
Retroperitoneal fat weight3.010.020.4-4.54.3-3.6-3.53.8-3.6-0.3-2.4-1.31.1
Reaction time number correct0.60.92.00.6-1.01.30.9-1.41.3-0.20.80.9-0.1
Reaction time mean minus median1.82.45.92.1-1.51.41.8-1.11.42.4-0.0-0.2-1.7
Reaction time mean minus median AUC1.41.93.41.6-1.41.51.9-1.31.41.50.30.4-1.4
Reaction time num false alarms0.70.93.3-0.40.10.20.2-0.30.3-1.8-1.60.41.7
Reaction time num false alarms AUC0.71.02.50.3-0.40.60.6-0.70.7-1.6-1.60.41.5
Reaction time trials correct on left0.60.92.00.6-1.01.30.9-1.41.3-0.20.80.9-0.1
Reaction time trials on left0.81.12.40.7-1.21.41.1-1.61.5-0.20.80.9-0.1
Reaction time mean0.30.41.90.2-0.20.10.60.20.01.20.60.1-1.4
Reaction time mean AUC0.30.41.80.10.0-0.00.40.3-0.11.30.4-0.1-1.3
Median of all reaction times0.20.31.0-0.30.3-0.4-0.00.6-0.40.80.6-0.0-1.0
Reaction time omissions0.81.12.11.4-1.21.21.4-1.11.20.80.30.2-0.7
Reaction time false alarm rate0.60.84.0-0.40.4-0.10.00.1-0.1-1.3-2.0-0.01.5
Reaction time premature initiation rate1.72.23.91.8-2.01.31.8-1.71.3-1.31.50.71.0
Reaction time premature initiations3.24.57.92.4-2.82.32.5-2.72.3-1.32.11.40.5
Std. dev. reaction times0.71.02.51.1-0.90.71.4-0.50.71.60.40.1-1.5
Reaction time trials completed0.81.12.40.7-1.21.41.1-1.61.5-0.20.80.9-0.1
Reaction time trials AUC0.50.71.70.5-0.91.20.8-1.31.2-0.30.60.80.1
Run reversals in cocaine runway, females1.81.76.30.70.6-0.9-0.90.7-0.8-0.8-1.8-1.82.5
Run reversals in cocaine runway, males0.90.92.6-0.4-0.51.20.9-1.21.2-0.80.11.6-0.4
Latency to leave start box in cocaine runway0.90.93.7-0.00.9-0.8-0.81.0-0.80.7-1.9-1.30.4
Latency to leave start box in cocaine runway, F0.20.30.60.10.5-0.5-0.50.6-0.50.5-0.6-0.8-0.1
Latency to leave start box in cocaine runway, M0.50.53.60.10.30.0-0.10.10.00.6-1.9-0.60.5
Std. dev. time between licks in bursts0.50.63.2-0.3-0.30.30.3-0.50.3-1.8-0.30.61.4
Total sessions with >9 infusions2.62.94.1-1.32.0-2.0-2.01.8-1.8-0.3-1.9-1.51.5
Short access day 1 total inactive lever presses2.42.64.5-2.02.1-2.0-1.92.0-1.9-0.7-0.9-0.70.9
Short access day 10 total inactive lever presses1.92.14.3-2.01.6-1.3-1.51.4-1.4-2.1-0.70.11.4
Short access day 1 total infusions4.85.18.9-1.72.7-2.9-3.02.7-2.60.0-1.8-2.01.3
Short access day 10 total infusions5.56.18.8-0.92.7-3.0-2.93.0-2.81.0-2.9-2.91.2
Short access total infusions3.43.86.1-1.02.2-2.5-2.42.3-2.20.3-2.0-2.11.4
Short access day 1 locomotion4.04.37.0-1.22.4-2.6-2.62.3-2.2-0.3-2.3-1.81.6
Short access day 10 total locomotion3.13.56.0-1.12.2-2.3-2.42.2-2.10.1-1.9-1.81.2
Short access total locomotion3.13.35.6-0.92.0-2.3-2.42.0-2.0-0.2-1.7-1.81.5
One hour access (0.3 mA shock)4.55.211.3-3.43.1-2.7-2.82.7-2.6-0.0-1.4-0.3-0.4
Compulsive drug intake2.22.24.01.6-2.01.61.6-1.71.3-1.71.31.00.7
One hour access (shock baseline)4.24.99.8-3.13.0-2.5-2.52.6-2.21.4-1.4-0.4-1.5
Social response proportion0.30.41.01.0-0.80.30.5-0.30.20.80.8-0.1-0.7
Social responses0.20.30.60.7-0.80.40.7-0.50.3-0.20.60.5-0.3
Social time0.50.61.50.8-1.00.61.0-0.80.6-0.41.20.6-0.0
Soleus weight1.64.714.2-3.83.0-1.8-2.52.2-2.1-1.1-1.6-0.11.1
Bone: stiffness1.01.67.12.2-0.70.40.2-0.20.42.7-0.1-1.5-0.9
Tibialis anterior weight6.622.444.36.7-5.75.95.6-5.55.62.92.51.2-2.2
Time to tail flick, vehicle, before self-admin0.30.31.40.6-0.0-0.0-0.10.1-0.11.2-0.9-0.90.1
Time to tail flick, vehicle, after self-admin0.50.51.81.2-0.2-0.1-0.1-0.1-0.00.1-0.9-1.21.3
Time to tail flick, test, before self-admin2.82.75.2-0.61.7-1.7-1.91.6-1.6-0.4-2.3-1.72.0
Time to tail flick, test, after self-admin0.10.10.10.0-0.30.20.4-0.30.2-0.10.30.4-0.1
Delta time to tail flick, vehicle, before/after SA0.20.20.60.7-0.2-0.1-0.1-0.1-0.0-0.4-0.2-0.60.8
Delta time to tail flick, test, before/after SA4.64.28.00.8-2.22.12.4-2.22.00.22.82.2-2.0
Tibia length1.74.78.91.8-1.82.52.2-2.02.43.00.50.9-3.0
Ambulatory time before self-admin0.80.83.50.6-0.40.60.5-0.30.41.90.2-0.1-1.7
Ambulatory time after self-admin0.30.41.0-0.30.5-0.4-0.40.7-0.51.00.1-0.5-1.0
Bone: tissue strength0.10.10.60.20.0-0.1-0.10.2-0.10.8-0.2-0.2-0.4
Total heroin consumption2.73.17.52.7-2.22.02.0-2.02.11.20.80.1-0.7
Bone: trabecular number0.71.13.81.00.3-0.9-0.31.0-1.01.9-0.3-1.6-0.6
Bone: trabecular spacing0.30.42.5-0.60.10.1-0.2-0.20.1-1.6-0.40.51.1
Bone: trabecular thickness1.01.22.5-0.61.2-1.6-1.21.6-1.60.4-0.5-1.20.1
Bone: trabecular tissue density1.01.46.0-2.41.5-0.6-1.30.9-0.7-0.5-1.10.6-0.3
Water consumed over 24 hours0.70.93.71.0-1.20.40.8-0.60.4-0.51.90.6-0.6
Number of responses in last shaping day0.60.61.9-1.00.6-0.9-0.70.5-0.6-1.40.60.40.5