Hub : Traits : Tibialis anterior weight : ← : →

chr2:119,815,737-122,186,612

Trait: Tibialis anterior weight

Best TWAS P = 2.93e-09 · Best GWAS P= 9.11e-09 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Atp11b	gene expression	Atp11b	0.11	10	0.06	9.9e-07	-5.6	2.10e-08	0.64	FALSE
Adipose	Qrfpr	gene expression	Qrfpr	0.25	21	0.14	4.8e-15	-5.47	4.55e-08	0.57	FALSE
Adipose	Atp11b	mRNA stability	Atp11b	0.16	21	0.08	6.2e-09	5.41	6.23e-08	0.65	FALSE
BLA	Mccc1	alternative TSS	XM_063281564.1	0.07	2373	0	1.8e-01	-5.47	4.48e-08	0.27	FALSE
BLA	LOC134485901	gene expression	LOC134485901	0.08	1	0.02	1.9e-02	5.58	2.43e-08	0.04	FALSE
BLA	Qrfpr	gene expression	Qrfpr	0.33	1	0.19	2.9e-10	-5.41	6.26e-08	0.29	FALSE
BLA	Mccc1	isoform ratio	XM_063281564.1	0.08	2373	0.01	6.6e-02	-5.71	1.16e-08	0.37	FALSE
Brain	LOC134485901	alternative polyA	XR_010064255.1	0.04	2356	0.02	1.0e-02	5.33	9.58e-08	0.39	FALSE
Brain	LOC134485901	alternative polyA	XR_010064256.1	0.04	2356	0.02	8.6e-03	-5.33	1.00e-07	0.39	FALSE
Brain	Mccc1	alternative polyA	XM_039101988.2	0.03	2373	0.01	1.2e-02	-5.62	1.95e-08	0.45	FALSE
Brain	Mccc1	alternative polyA	XM_039101989.2	0.03	1	0.02	9.3e-03	-5.45	5.10e-08	0.45	TRUE
Brain	Mccc1	alternative TSS	NM_001009653.1	0.03	2373	0.02	6.7e-03	5.59	2.28e-08	0.45	FALSE
Brain	Qrfpr	gene expression	Qrfpr	0.67	2559	0.64	5.5e-77	5.67	1.46e-08	0.58	FALSE
Brain	Atp11b	isoform ratio	NM_001427027.1	0.03	1909	0.03	1.5e-03	-5.32	1.04e-07	0.38	FALSE
Brain	LOC134485901	isoform ratio	XR_010064255.1	0.03	21	0.02	7.4e-03	-5.38	7.54e-08	0.4	FALSE
Brain	LOC134485901	isoform ratio	XR_010064256.1	0.03	20	0.02	7.6e-03	5.38	7.49e-08	0.41	TRUE
Brain	Mccc1	isoform ratio	XM_039101989.2	0.03	1	0.02	2.2e-03	-5.45	5.10e-08	0.03	FALSE
Brain	Trpc3	isoform ratio	XM_008760941.4	0.12	2118	0.1	2.3e-09	-5.28	1.28e-07	0.19	FALSE
Brain	Trpc3	intron excision ratio	chr2_121413430_121424497	0.04	2118	0.03	1.3e-03	5.44	5.33e-08	0.48	FALSE
Brain	Qrfpr	mRNA stability	Qrfpr	0.43	29	0.31	2.4e-29	5.94	2.93e-09	0.57	TRUE
IC	Qrfpr	gene expression	Qrfpr	0.71	35	0.59	5.0e-30	5.62	1.93e-08	0.56	FALSE
IC	Anxa5	intron excision ratio	chr2_121254178_121255525	0.3	2448	0.26	3.9e-11	5.57	2.57e-08	0.44	FALSE
IL	Qrfpr	gene expression	Qrfpr	0.75	1	0.24	1.6e-06	-5.39	6.98e-08	0.08	FALSE
LHb	Qrfpr	gene expression	Qrfpr	0.24	15	0.05	2.6e-02	-5.52	3.47e-08	0.36	TRUE
Liver	Atp11b	alternative polyA	XM_039103614.2	0.04	1	0.01	5.5e-02	-5.49	4.02e-08	0.03	FALSE
Liver	Atp11b	alternative polyA	XM_039103615.2	0.04	1	0.01	3.6e-02	5.49	4.02e-08	0.03	FALSE
Liver	Atp11b	alternative polyA	XM_039103614.2	0.03	1	0.01	7.2e-02	-5.49	4.02e-08	0.03	FALSE
Liver	Atp11b	alternative polyA	XM_039103615.2	0.04	1	0.01	4.5e-02	5.49	4.02e-08	0.03	FALSE
Liver	Dcun1d1	alternative polyA	XM_006232261.5	0.03	1	0.01	5.7e-02	5.52	3.38e-08	0.03	FALSE
Liver	Dcun1d1	alternative polyA	NM_001395100.1	0.05	2255	0.02	2.6e-03	5.62	1.87e-08	0.5	FALSE
Liver	Dcun1d1	alternative polyA	XM_006232261.5	0.04	3	0.02	4.5e-03	5.67	1.44e-08	0.48	FALSE
Liver	Dcun1d1	gene expression	Dcun1d1	0.16	1	0.08	1.3e-09	5.45	5.10e-08	0.31	FALSE
Liver	Mccc1	gene expression	Mccc1	0.34	2373	0.22	1.3e-23	5.48	4.18e-08	0.48	FALSE
Liver	Anxa5	intron excision ratio	chr2_121254178_121255525	0.04	1	0.01	1.8e-02	-5.22	1.75e-07	0.03	FALSE
Liver	Bbs7	mRNA stability	Bbs7	0.09	1	0.06	4.6e-07	-5.22	1.75e-07	0.22	FALSE
NAcc	Mccc1	alternative polyA	XM_039101988.2	0.06	1	0.04	2.2e-06	5.49	4.02e-08	0.26	FALSE
NAcc	Mccc1	alternative polyA	XM_039101989.2	0.06	2373	0.03	1.2e-05	5.26	1.43e-07	0.47	TRUE
NAcc	Atp11b	alternative TSS	XM_039103616.1	0.09	1	0.02	1.5e-04	-5.53	3.16e-08	0.04	FALSE
NAcc	Ccdc144b	gene expression	Ccdc144b	0.04	2428	0.01	2.2e-03	-5.39	7.18e-08	0.51	FALSE
NAcc	Atp11b	isoform ratio	NM_001427027.1	0.04	43	0.02	7.6e-04	5.49	4.02e-08	0.36	FALSE
NAcc	Atp11b	isoform ratio	XM_039103616.1	0.04	1	0.03	5.5e-05	-5.53	3.16e-08	0.09	FALSE
NAcc	Mccc1	isoform ratio	XM_039101989.2	0.04	2373	0.02	2.3e-04	5.47	4.42e-08	0.52	FALSE
OFC	Qrfpr	gene expression	Qrfpr	0.83	200	0.42	3.7e-11	-5.62	1.87e-08	0.5	FALSE
OFC	Qrfpr	mRNA stability	Qrfpr	0.46	1	0.29	1.6e-07	-5.39	6.98e-08	0.07	FALSE
PL	Dcun1d1	alternative polyA	NM_001395100.1	0.03	2255	0.01	7.5e-03	5.71	1.14e-08	0.45	FALSE
PL	Dcun1d1	alternative polyA	XM_006232261.5	0.03	2255	0.01	9.2e-03	-5.69	1.25e-08	0.43	FALSE
PL	Dcun1d1	alternative polyA	NM_001395100.1	0.04	2255	0.02	3.0e-03	5.69	1.24e-08	0.52	FALSE
PL	Dcun1d1	alternative polyA	XM_006232261.5	0.03	2255	0.02	3.5e-03	-5.67	1.39e-08	0.51	FALSE
PL	Mccc1	alternative polyA	XM_039101988.2	0.09	1	0.08	5.9e-09	5.61	1.99e-08	0.52	FALSE
PL	Mccc1	alternative polyA	XM_039101989.2	0.09	1	0.08	5.3e-09	-5.61	1.99e-08	0.52	FALSE
PL	Atp11b	alternative TSS	XM_039103616.1	0.04	1	0.02	4.5e-03	-5.71	1.12e-08	0.07	FALSE
PL	Mccc1	alternative TSS	XM_063281564.1	0.03	2373	0.01	1.8e-02	-5.68	1.37e-08	0.46	FALSE
PL	Bbs7	gene expression	Bbs7	0.12	1	0.07	4.8e-08	5.22	1.75e-07	0.23	TRUE
PL	Qrfpr	gene expression	Qrfpr	0.59	47	0.57	5.0e-76	5.88	4.20e-09	0.6	FALSE
PL	Atp11b	isoform ratio	NM_001427027.1	0.07	1	0.04	2.5e-05	5.71	1.12e-08	0.38	FALSE
PL	Atp11b	isoform ratio	XM_039103616.1	0.06	1	0.03	3.9e-04	-5.71	1.12e-08	0.35	FALSE
PL	Dcun1d1	isoform ratio	NM_001395100.1	0.03	2255	0.01	2.0e-02	5.63	1.84e-08	0.39	FALSE
PL	Mccc1	isoform ratio	XM_039101989.2	0.08	1	0.06	2.6e-07	-5.49	4.02e-08	0.35	FALSE
PL	Mccc1	isoform ratio	XM_063281564.1	0.03	2373	0.01	1.1e-02	-5.67	1.42e-08	0.45	FALSE
PL	Qrfpr	mRNA stability	Qrfpr	0.14	1	0.13	1.6e-13	-5.54	2.96e-08	0.45	FALSE
pVTA	Dcun1d1	alternative polyA	NM_001395100.1	0.09	1	0.04	6.8e-04	-5.53	3.16e-08	0.12	FALSE
pVTA	Dcun1d1	alternative polyA	XM_006232261.5	0.14	2255	0.03	1.0e-03	-5.28	1.32e-07	0.54	FALSE
pVTA	Dcun1d1	alternative polyA	NM_001395100.1	0.1	1	0.03	1.3e-03	-5.53	3.16e-08	0.09	FALSE
pVTA	Dcun1d1	alternative polyA	XM_006232261.5	0.1	1	0.03	1.4e-03	5.53	3.16e-08	0.08	FALSE
pVTA	Ccdc144b	alternative TSS	XM_039103619.2	0.04	2428	0.03	4.2e-03	5.38	7.25e-08	0.4	FALSE
pVTA	Mccc1	gene expression	Mccc1	0.19	4	0.15	3.2e-12	5.64	1.73e-08	0.56	FALSE