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chr2:99,969,887-102,351,095

Best TWAS P=1.377141e-07 · Best GWAS P=8.17287e-08 conditioned to 0.0604391

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	BLA	Cyp7b1	gene expression	ENSRNOG00000009730	0.43	0.27	enet	71	0.29	5.8e-16	-5.2	5.1	3.2e-07	-0.77	0.55	0.45	FALSE
2	Brain	Cyp7b1	intron excision ratio	chr2:100638373:100669465	0.04	0.02	enet	17	0.04	2.6e-04	-5.2	5.3	1.4e-07	-0.81	0.56	0.38	TRUE
3	LHb	Armc1	gene expression	ENSRNOG00000013253	0.31	0.20	top1	1	0.20	1.4e-05	-5.2	-5.2	2.1e-07	0.92	0.09	0.09	FALSE
4	NAcc2	Cyp7b1	gene expression	ENSRNOG00000009730	0.23	0.19	lasso	18	0.19	1.4e-10	-5.1	5.2	2.2e-07	-0.90	0.69	0.31	FALSE
5	NAcc2	Armc1	gene expression	ENSRNOG00000013253	0.19	0.04	top1	1	0.04	2.2e-03	-5.1	-5.1	3.0e-07	0.79	0.07	0.07	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.