Hub : Genes

Rusc2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative TSS XM_039110999.1 0.06 0.04 5.0e-06 0.04 0.05 0.06 0.05 8.2e-05 1.1e-05 3.9e-06 8.9e-06
2 pVTA alternative TSS XM_039111002.1 0.07 0.05 2.8e-03 0.03 0.04 0.03 0 2.6e-02 8.0e-03 1.7e-02 1.8e-01
3 Brain alternative TSS XM_039111002.1 0.05 0.04 1.3e-05 0.05 0.04 0.04 0.05 3.3e-05 4.9e-05 5.1e-05 2.5e-05
4 Brain alternative TSS XM_039111004.1 0.1 0.06 2.7e-10 0.09 0.1 0.11 0.1 1.2e-08 1.0e-09 2.5e-10 5.6e-10
5 Brain alternative TSS XM_039110999.1 0.04 0.03 2.8e-04 0.03 0.04 0.03 0.02 5.9e-04 3.0e-04 8.0e-04 2.8e-03
6 NAcc isoform ratio XM_003749927.4 0.02 0.02 8.2e-04 0.02 0.03 0.02 0.03 1.2e-03 2.9e-04 8.1e-04 5.5e-04
7 pVTA alternative TSS XM_039111002.1 0.08 0.05 5.5e-04 0.05 0.06 0.06 -0 3.7e-03 9.4e-04 1.4e-03 3.4e-01
8 Brain gene expression Rusc2 0.05 0.03 3.0e-05 0.02 0.03 0.03 0.02 7.7e-03 4.8e-04 6.2e-04 2.9e-03
9 pVTA alternative TSS XM_039110999.1 0.05 0.04 4.0e-03 0.05 0.05 0.04 -0.01 3.9e-03 3.0e-03 4.9e-03 9.7e-01
10 NAcc gene expression Rusc2 0.04 0.04 7.0e-05 0.04 0.03 0.03 0.04 1.1e-05 2.0e-04 4.8e-04 6.0e-05
11 OFC mRNA stability Rusc2 0.18 0.15 4.0e-03 0.11 -0 0.06 -0 1.2e-03 4.1e-01 1.2e-02 3.4e-01
12 pVTA alternative TSS XM_039110999.1 0.11 0.07 1.0e-04 0.1 0.07 0.09 -0.01 2.7e-05 5.2e-04 8.7e-05 8.9e-01
13 PL alternative TSS XM_039110999.1 0.02 0.01 9.2e-03 0.01 0.01 0.01 0.01 1.0e-02 1.1e-02 1.3e-02 1.4e-02
14 NAcc alternative TSS XM_003749927.4 0.02 0.02 2.9e-03 0.02 0.02 0.02 0.02 1.3e-03 1.1e-03 6.9e-04 1.3e-03
15 NAcc alternative TSS XM_003749927.4 0.02 0.02 9.1e-03 0.01 0.02 0.02 0.02 5.7e-03 3.8e-03 1.6e-03 3.8e-03
16 PL alternative TSS XM_039111004.1 0.04 0.03 5.9e-06 0.04 0.05 0.05 0.05 9.6e-06 2.5e-06 4.8e-06 7.6e-06
17 Brain alternative TSS XM_039111002.1 0.03 0.02 7.0e-04 0.03 0.02 0.03 0.03 7.4e-04 2.4e-03 1.0e-03 1.2e-03
18 pVTA alternative TSS XM_039111004.1 0.14 0.09 1.2e-06 0.14 0.15 0.14 0.07 8.8e-07 6.9e-07 1.6e-06 5.6e-04
19 Adipose mRNA stability Rusc2 0.03 0.02 7.9e-03 0.02 0.01 0.01 0.01 4.1e-03 3.3e-02 1.1e-02 1.8e-02
20 Liver intron excision ratio chr5_57672695_57672887 0.06 0.04 1.1e-04 0.03 0.03 0.02 0.03 2.4e-04 4.7e-04 1.0e-03 4.2e-04
21 Liver intron excision ratio chr5_57672695_57673342 0.09 0.05 7.0e-07 0.05 0.05 0.05 0.05 4.4e-06 3.2e-06 1.3e-06 2.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density1.32.22.8-1.6-1.6-1.6-1.6-1.61.6-1.61.61.71.51.61.61.6-1.7-1.71.71.51.60.40.4-0.4
Area under the delay curve0.60.71.10.60.80.60.60.7-0.80.8-0.8-0.9-1.0-1.1-1.1-1.00.70.8-0.9-0.5-1.0-0.8-0.80.8
BMI with tail2.99.312.4-3.2-3.1-3.3-3.4-3.23.2-3.23.23.33.23.13.13.2-3.5-3.53.43.43.30.80.9-0.9
BMI without tail5.511.315.1-3.8-3.9-3.8-3.8-3.83.7-3.83.83.63.73.73.63.5-3.4-3.53.43.43.1-0.7-0.70.7
Body weight3.414.418.3-4.3-4.2-4.3-4.3-4.34.3-4.24.24.14.03.93.93.8-4.1-4.14.04.03.7-0.5-0.50.4
Weight adjusted by age0.30.31.4-0.5-0.3-0.4-0.5-0.30.3-0.20.20.1-0.2-0.2-0.0-0.3-0.4-0.30.00.3-0.2-1.2-1.21.2
Bone surface0.61.11.5-1.2-1.2-1.2-1.2-1.21.2-1.21.11.11.01.01.01.0-1.2-1.21.11.00.9-0.5-0.50.5
Bone volume0.71.11.4-1.1-1.2-1.1-1.2-1.21.2-1.21.21.21.11.11.11.1-1.2-1.21.21.01.1-0.1-0.10.1
Breakpoint value in progressive ratio session1.11.23.60.60.60.60.60.6-0.60.7-0.8-0.9-1.2-1.2-1.1-1.30.50.5-1.0-0.9-1.3-1.9-1.91.8
Number of licking bursts4.65.47.3-2.5-2.6-2.5-2.5-2.52.5-2.62.62.62.72.72.72.7-2.1-2.22.52.32.50.50.5-0.5
Context. condit. distance diff. score0.10.10.10.30.30.30.30.3-0.20.2-0.3-0.2-0.2-0.2-0.2-0.30.10.1-0.1-0.2-0.00.40.4-0.4
Locomotion velocity, session 11.71.811.7-0.3-0.4-0.2-0.2-0.40.3-0.20.1-0.3-0.3-0.4-0.4-0.4-0.2-0.2-0.5-0.4-1.0-3.4-3.43.4
Locomotion distance, session 10.50.63.7-0.5-0.5-0.4-0.4-0.40.4-0.30.30.10.10.00.0-0.0-0.3-0.2-0.10.1-0.4-1.9-1.91.9
Locomotion velocity, session 22.73.24.4-2.0-1.8-2.0-2.0-1.91.9-1.91.91.91.81.81.81.8-2.0-2.01.92.11.90.60.6-0.6
Locomotion distance, session 21.31.82.8-1.6-1.7-1.6-1.5-1.51.4-1.51.51.21.41.41.41.4-0.8-0.81.01.20.7-1.4-1.41.4
Locomotion velocity, session 30.40.42.70.0-0.10.10.1-0.0-0.00.1-0.1-0.3-0.3-0.3-0.3-0.30.10.2-0.4-0.4-0.7-1.6-1.61.6
Locomotion distance, session 32.12.33.7-1.7-1.7-1.6-1.7-1.71.7-1.61.61.51.31.31.31.3-1.9-1.91.41.41.1-1.2-1.21.2
Stereotopy head waving bouts, day 30.81.02.50.70.50.70.80.5-0.60.6-0.6-0.9-0.7-0.8-0.8-0.81.21.1-1.0-1.1-1.2-1.6-1.61.6
Stereotopy head waving duration, day 30.80.91.60.90.80.91.00.8-0.90.9-0.9-1.0-0.8-1.0-1.0-0.91.31.2-1.1-1.1-1.2-0.9-0.90.9
Locomotion velocity, session 70.00.00.10.20.20.20.20.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.20.10.2-0.2-0.2-0.20.10.1-0.1
Locomotion distance, session 70.20.20.3-0.5-0.5-0.5-0.5-0.50.5-0.50.50.40.30.40.40.4-0.6-0.50.40.40.3-0.5-0.50.5
Stereotopy head waving bouts, day 71.92.22.9-1.6-1.7-1.6-1.7-1.71.7-1.71.61.51.51.41.41.5-1.7-1.71.51.41.3-0.7-0.70.7
Stereotopy head waving duration, day 70.40.40.7-0.7-0.8-0.7-0.7-0.80.7-0.70.70.60.70.60.60.7-0.4-0.50.50.50.4-0.7-0.70.7
Locomotion velocity, session 80.30.41.60.10.00.10.30.2-0.30.2-0.2-0.4-0.2-0.3-0.3-0.20.80.8-0.6-0.5-0.8-1.3-1.31.3
Locomotion distance, session 80.20.31.5-0.3-0.4-0.3-0.2-0.30.3-0.30.30.10.20.20.20.10.10.1-0.00.0-0.2-1.2-1.21.2
Degree of sensitization distance1.21.22.31.21.21.11.31.2-1.31.2-1.1-1.1-1.0-0.9-0.9-1.01.51.5-1.1-1.1-1.00.50.5-0.5
Degree of sensitization stereotypy1.41.52.5-1.3-1.3-1.3-1.4-1.41.4-1.31.31.31.21.11.11.2-1.6-1.61.31.21.2-0.3-0.30.2
Conditioned locomotion0.30.41.80.20.20.30.20.2-0.20.3-0.3-0.4-0.6-0.4-0.5-0.6-0.2-0.2-0.4-0.4-0.6-1.1-1.31.3
Cocaine response after cond. corrected2.93.24.51.71.51.71.71.6-1.61.7-1.7-1.9-1.9-1.9-1.9-1.91.61.6-1.9-2.0-2.1-1.9-1.81.9
Cocaine response after cond. not corrected2.93.24.71.61.41.61.71.5-1.51.6-1.6-1.8-1.8-1.7-1.7-1.71.81.8-2.0-2.0-2.2-2.1-2.12.1
Cocaine response before conditioning0.70.81.4-1.0-1.1-1.0-0.9-1.00.9-1.01.01.01.21.21.21.1-0.4-0.40.80.90.90.30.2-0.2
Saline control response0.60.83.0-0.7-1.0-0.6-0.6-0.90.8-0.80.80.60.80.60.60.7-0.3-0.30.40.20.1-1.7-1.61.6
Bone: connectivity density0.91.32.2-1.2-1.1-1.2-1.3-1.21.2-1.21.21.31.01.11.11.1-1.5-1.51.31.31.30.60.6-0.6
Bone: cortical apparent density0.40.63.40.10.10.1-0.10.1-0.0-0.00.00.30.50.40.40.4-0.2-0.20.40.30.71.91.9-1.9
Bone: cortical area2.53.75.1-2.0-2.0-2.1-2.1-2.02.0-2.12.12.12.32.12.12.2-1.9-1.92.12.02.10.80.8-0.9
Bone: cortical porosity0.40.50.70.70.80.70.80.7-0.70.7-0.7-0.7-0.8-0.8-0.8-0.70.70.7-0.7-0.7-0.60.10.1-0.1
Bone: cortical porosity0.00.00.0-0.00.0-0.0-0.0-0.00.00.0-0.0-0.0-0.2-0.2-0.2-0.1-0.1-0.10.00.0-0.0-0.0-0.00.0
Bone: cortical thickness1.32.23.1-1.3-1.2-1.3-1.4-1.31.3-1.41.31.51.61.51.51.6-1.6-1.61.61.51.81.51.5-1.5
Bone: cortical thickness0.10.10.60.30.30.30.30.3-0.30.2-0.3-0.20.1-0.0-0.00.00.10.2-0.2-0.2-0.00.80.8-0.8
Bone: cortical tissue density0.40.53.00.20.20.20.10.2-0.20.1-0.10.10.30.30.30.3-0.1-0.10.20.20.51.71.7-1.7
Condit. Reinf. active minus inactive responses0.60.60.9-0.9-0.8-0.9-0.9-0.80.8-0.80.90.90.81.01.00.9-0.7-0.60.80.90.90.40.4-0.4
Condit. Reinf. active-inactive response ratio0.50.50.70.80.80.80.80.9-0.80.8-0.8-0.7-0.6-0.6-0.6-0.50.80.8-0.7-0.7-0.50.50.6-0.5
Condit. Reinf. active responses3.03.64.7-2.2-2.0-2.2-2.1-2.02.0-2.02.12.12.12.22.22.1-1.7-1.72.02.12.00.60.5-0.5
Condit. Reinf. inactive responses3.64.35.8-2.3-2.2-2.3-2.2-2.22.2-2.22.32.32.42.32.32.3-1.8-1.82.22.32.20.90.8-0.8
Incentive salience index mean4.14.96.9-2.6-2.5-2.6-2.5-2.52.5-2.52.52.42.32.42.42.3-2.1-2.12.32.42.1-0.2-0.20.2
Condit. Reinf. lever presses8.911.816.8-4.1-4.0-4.0-3.9-4.03.9-3.93.93.63.43.53.53.4-3.3-3.33.53.63.0-1.3-1.41.3
Condit. Reinf. active minus inactive responses0.70.91.1-1.0-1.0-1.0-1.1-1.01.0-1.11.01.10.91.01.01.0-1.0-1.01.11.01.00.20.2-0.2
Condit. Reinf. active-inactive response ratio0.20.30.5-0.5-0.4-0.5-0.5-0.50.5-0.50.50.60.40.40.30.4-0.7-0.70.60.60.70.30.5-0.5
Condit. Reinf. active responses2.23.03.9-2.0-2.0-2.0-2.0-1.91.9-1.91.91.91.81.91.91.9-1.6-1.61.81.81.7-0.0-0.10.0
Condit. Reinf. inactive responses3.13.85.4-2.1-2.1-2.1-2.1-2.12.0-2.12.12.12.12.32.32.2-1.7-1.72.02.12.00.70.5-0.5
Condit. Reinf. lever presses2.83.84.8-2.0-1.9-2.1-2.1-2.02.0-2.02.12.12.12.22.22.1-1.7-1.72.12.22.21.21.1-1.1
Condit. Reinf. lever reinforcers received2.53.54.7-2.2-2.1-2.1-2.1-2.12.1-2.12.12.11.92.12.02.0-1.7-1.82.02.01.90.0-0.10.0
Conditioned reinforcement - actives0.30.31.2-0.6-0.3-0.6-0.6-0.50.6-0.40.40.50.00.10.00.2-1.1-1.10.70.80.60.20.2-0.2
Conditioned reinforcement - inactives0.10.10.20.20.30.20.10.2-0.20.3-0.3-0.2-0.5-0.4-0.4-0.3-0.1-0.1-0.20.0-0.2-0.3-0.30.3
Conditioned locomotion0.50.62.2-0.8-0.6-0.8-0.8-0.70.8-0.70.60.70.10.40.30.3-1.5-1.40.90.90.7-0.2-0.20.2
Patch foraging indifference point 0 sec0.81.37.5-0.6-0.5-0.5-0.6-0.70.7-0.40.30.1-0.4-0.4-0.4-0.4-1.0-1.00.10.1-0.4-2.7-2.72.7
Patch foraging indifference point AUC7.48.612.0-3.5-3.4-3.4-3.4-3.43.4-3.33.33.22.72.92.93.0-3.0-3.03.13.12.8-0.7-0.70.6
Delay disc. indifference point, 0s delay1.61.82.31.31.31.31.41.3-1.41.4-1.4-1.4-1.5-1.5-1.5-1.51.41.3-1.5-1.4-1.5-0.7-0.70.7
Delay disc. indifference point, 16s delay1.71.72.71.01.11.11.01.1-1.11.2-1.3-1.4-1.5-1.6-1.6-1.51.01.1-1.4-1.1-1.6-1.5-1.51.5
Delay disc. indifference point, 2s delay0.10.10.3-0.2-0.1-0.2-0.2-0.10.2-0.20.20.30.20.20.20.2-0.3-0.20.30.40.40.60.6-0.6
Delay disc. indifference point, 24s delay0.20.20.50.40.40.40.40.4-0.40.4-0.4-0.4-0.3-0.3-0.3-0.30.60.7-0.5-0.3-0.40.00.0-0.0
Delay disc. indifference point, 4s delay0.10.10.20.20.30.20.20.3-0.30.3-0.3-0.3-0.3-0.4-0.4-0.30.20.2-0.3-0.1-0.3-0.1-0.10.1
Delay disc. indifference point, 8s delay0.00.00.2-0.3-0.1-0.3-0.3-0.10.1-0.10.10.10.1-0.0-0.00.1-0.00.00.00.50.0-0.2-0.20.2
Indifference point function ln k2.53.54.92.22.12.22.22.1-2.12.1-2.1-2.0-1.9-1.8-1.8-2.01.91.9-2.0-2.0-1.80.20.1-0.1
Indifference point function log k2.53.54.92.22.12.22.22.1-2.12.1-2.1-2.0-1.9-1.8-1.8-2.01.91.9-2.0-2.0-1.80.20.1-0.1
Patch foraging total patch changes 0 sec1.01.56.7-1.0-0.9-0.9-1.0-1.11.1-0.90.70.6-0.0-0.0-0.00.0-1.4-1.50.60.50.0-2.6-2.62.6
Patch foraging total patch changes 12 sec2.53.25.4-2.0-1.9-2.0-2.1-2.02.1-2.01.92.01.51.61.61.6-2.3-2.32.01.91.8-0.3-0.30.2
Patch foraging total patch changes 18 sec0.60.81.2-1.1-1.1-1.1-1.1-1.11.1-1.01.00.90.60.70.70.8-0.9-0.90.90.90.7-0.8-0.80.7
Patch foraging total patch changes 24 sec2.42.94.8-2.1-1.9-2.0-2.0-2.02.0-1.91.81.71.11.21.21.3-2.2-2.21.81.71.4-1.1-1.11.1
Patch foraging total patch changes 6 sec2.63.96.6-2.3-2.1-2.2-2.3-2.22.3-2.12.01.81.11.31.21.3-2.6-2.61.81.81.3-2.0-2.01.9
Patch foraging time to switch 0 sec2.53.95.42.32.32.32.32.3-2.32.2-2.2-2.0-1.6-1.6-1.6-1.72.32.3-2.0-1.9-1.61.21.3-1.2
Patch foraging water rate 0 sec1.82.85.9-1.8-1.8-1.7-1.9-1.92.0-1.81.71.61.31.01.11.2-2.4-2.41.61.41.2-1.5-1.51.5
Patch foraging water rate 12 sec0.10.10.60.1-0.10.1-0.0-0.10.1-0.10.0-0.1-0.0-0.2-0.1-0.0-0.1-0.1-0.1-0.3-0.2-0.8-0.70.7
Patch foraging water rate 18 sec0.60.81.9-0.8-0.8-0.8-1.0-0.90.9-0.90.80.90.80.70.70.7-1.4-1.41.10.91.00.50.5-0.5
Patch foraging water rate 24 sec0.30.52.0-0.2-0.1-0.2-0.4-0.20.3-0.30.30.50.50.30.30.4-0.9-0.90.70.50.81.41.4-1.4
Patch foraging water rate 6 sec0.50.71.1-0.9-1.0-0.8-0.8-0.90.9-1.00.90.91.10.91.00.9-0.9-0.90.80.60.7-0.2-0.30.3
Seeking ratio, delayed vs. immediate footshock4.35.07.6-2.4-2.2-2.5-2.6-2.42.4-2.32.32.42.32.22.12.0-2.7-2.72.42.82.40.30.3-0.4
Distance traveled before self-admin3.53.75.6-2.2-2.4-2.2-2.1-2.32.2-2.22.21.92.02.12.11.8-1.8-1.81.81.81.5-1.1-1.11.2
Distance traveled after self-admin0.70.71.7-0.8-0.9-0.9-0.7-0.80.7-0.80.90.81.21.31.31.1-0.3-0.40.70.90.90.60.6-0.6
Extensor digitorum longus weight4.317.022.7-4.8-4.7-4.7-4.7-4.74.6-4.64.64.44.24.34.34.3-4.3-4.34.34.33.9-0.6-0.60.5
Bone: elastic displacement3.23.75.52.32.32.32.12.3-2.22.2-2.2-1.9-1.9-2.0-2.0-2.01.61.5-1.7-1.8-1.41.41.4-1.4
Bone: elastic work1.41.87.51.31.41.21.01.3-1.21.1-1.1-0.7-0.7-0.7-0.7-0.70.50.5-0.5-0.5-0.02.72.7-2.7
Bone: endosteal estimation0.71.42.3-1.4-1.5-1.4-1.3-1.41.3-1.41.41.11.31.21.21.2-0.8-0.81.01.00.7-1.2-1.21.1
Bone: endosteal perimeter0.71.52.4-1.4-1.5-1.4-1.3-1.41.4-1.41.31.11.21.11.11.0-0.9-0.90.90.90.6-1.5-1.51.5
Epididymis fat weight0.30.71.6-0.8-1.1-0.7-0.6-1.01.0-1.01.00.91.21.01.11.3-0.4-0.40.80.20.6-0.5-0.50.5
Delta time in closed arm before/after self-admin3.33.24.5-1.7-1.7-1.8-1.7-1.81.8-1.81.92.02.12.02.01.9-1.6-1.72.01.92.11.11.1-1.2
Delta time in open arm before/after self-admin0.70.71.10.60.80.60.60.8-0.80.8-0.8-0.9-1.1-1.0-1.0-0.80.80.8-0.9-0.6-1.0-0.8-0.80.8
Diff in mean of infusions in LGA sessions0.00.00.10.20.20.20.20.2-0.20.2-0.1-0.10.0-0.1-0.10.20.20.2-0.1-0.2-0.00.30.3-0.3
Delay discount exponential model param0.50.50.9-0.5-0.7-0.5-0.5-0.60.6-0.70.70.80.90.90.90.8-0.6-0.60.80.40.90.80.8-0.8
Extinction: sum of active levers before priming1.91.92.51.51.61.41.51.5-1.61.6-1.5-1.5-1.4-1.5-1.4-1.51.61.5-1.5-1.3-1.4-0.2-0.20.1
Active lever presses in extinction session 60.40.41.30.40.70.40.40.6-0.50.7-0.6-0.6-1.1-1.1-0.9-0.90.10.1-0.6-0.3-0.6-0.6-0.60.4
Bone: final force1.01.62.6-1.5-1.5-1.5-1.4-1.41.3-1.51.51.41.51.51.51.6-0.9-0.91.31.31.20.00.0-0.0
Bone: final moment0.81.32.2-1.3-1.3-1.3-1.2-1.21.1-1.31.31.21.41.41.41.5-0.7-0.71.11.11.10.30.3-0.3
Food consumed during 24 hour testing period0.60.71.1-1.0-1.0-0.9-0.9-1.00.9-0.90.90.81.01.01.01.0-0.7-0.60.70.80.6-0.7-0.70.6
Glucose1.01.52.1-1.3-1.4-1.3-1.3-1.41.4-1.41.41.31.41.21.31.3-1.3-1.31.31.01.1-0.4-0.40.4
Heart weight0.60.81.1-1.0-1.0-1.0-1.0-1.01.0-1.01.00.90.90.90.90.9-0.8-0.80.80.90.6-0.7-0.70.7
Delay discount hyperbolic model param0.40.40.8-0.4-0.6-0.4-0.4-0.60.6-0.60.60.70.80.90.90.8-0.5-0.50.70.30.80.70.7-0.7
Intermittent access intake day 1-15 change1.21.22.0-0.7-0.9-0.7-0.8-0.90.9-1.01.01.11.41.41.41.2-0.8-0.81.20.91.41.31.3-1.3
Intermittent access intake escalation1.61.62.6-1.0-1.2-1.0-1.0-1.21.2-1.31.31.41.61.51.61.4-1.1-1.11.41.01.51.11.1-1.1
Intermittent access intake escalation 22.32.23.4-1.1-1.2-1.2-1.2-1.21.3-1.41.31.51.81.71.81.7-1.4-1.41.61.41.81.61.6-1.6
Intermitt. access day 1 inactive lever presses0.70.81.2-0.9-1.0-0.9-1.0-1.01.0-1.00.90.90.91.01.01.0-1.1-1.00.90.90.9-0.2-0.20.2
Intermitt. access day 15 inactive lever presses0.10.10.5-0.0-0.1-0.0-0.1-0.20.2-0.10.10.00.10.20.1-0.2-0.2-0.1-0.0-0.0-0.1-0.7-0.70.7
Intermitt. access escalation Index0.70.61.2-0.8-1.1-0.7-0.6-1.00.9-1.00.90.71.00.90.90.7-0.4-0.40.60.20.4-1.0-1.01.0
Intermittent access day 1 total infusions0.70.92.20.40.80.50.30.6-0.50.7-0.8-0.8-1.5-1.4-1.5-1.2-0.2-0.2-0.7-0.4-0.9-1.3-1.31.3
Intermittent access day 15 total infusions0.60.72.1-0.9-0.7-0.8-1.0-0.91.0-0.80.80.90.40.50.50.6-1.5-1.41.00.90.9-0.1-0.10.1
Intermittent access terminal intake (last 3 days)0.80.92.8-1.0-0.8-1.0-1.1-1.01.1-0.90.91.00.50.60.50.7-1.7-1.71.11.00.9-0.3-0.30.2
Intermittent access total infusions0.91.03.4-1.1-0.8-1.0-1.2-1.01.1-0.90.90.90.30.40.40.6-1.8-1.81.11.10.9-0.6-0.60.6
Intermittent access day 1 locomotion1.01.02.90.61.00.60.50.8-0.71.0-1.0-1.0-1.7-1.7-1.7-1.5-0.2-0.1-0.8-0.4-1.0-1.0-1.01.1
Intermittent access day 15 total locomotion0.50.51.50.60.90.60.40.7-0.60.8-0.8-0.7-1.2-1.1-1.2-1.1-0.3-0.3-0.5-0.3-0.6-0.3-0.30.3
Intermittent access total locomotion0.20.30.80.30.70.30.10.5-0.30.5-0.6-0.4-0.9-0.8-0.9-0.8-0.7-0.7-0.10.1-0.10.20.2-0.2
Intermittent access standard deviation0.50.50.8-0.6-0.6-0.7-0.8-0.70.7-0.70.70.80.80.80.80.8-0.9-0.80.80.90.90.50.5-0.5
Left kidney weight0.41.11.9-1.1-1.2-1.1-1.1-1.21.2-1.11.10.90.90.80.90.8-1.0-1.00.80.80.5-1.4-1.31.3
Right kidney weight0.10.21.0-0.3-0.1-0.2-0.2-0.10.0-0.00.0-0.10.00.0-0.0-0.10.20.2-0.30.2-0.4-1.0-1.01.0
Cocaine induced anxiety1.41.63.01.61.31.61.61.3-1.31.3-1.3-1.3-1.2-1.2-1.2-1.21.41.5-1.3-1.7-1.3-0.1-0.10.1
Post-drug Anxiety0.10.20.4-0.2-0.6-0.2-0.0-0.40.3-0.40.40.30.60.60.60.60.40.50.1-0.30.1-0.3-0.30.3
Baseline Anxiety1.81.92.8-1.5-1.4-1.6-1.5-1.41.4-1.41.51.51.61.51.51.6-1.1-1.21.41.71.50.60.6-0.7
Tail length2.06.09.2-2.8-3.0-2.8-2.7-2.92.7-2.82.92.62.82.82.72.6-2.0-2.02.32.22.0-1.1-1.21.1
Length with tail0.62.13.3-1.6-1.8-1.6-1.5-1.71.6-1.71.71.41.51.51.41.3-1.0-1.01.21.10.9-1.4-1.51.4
Length without tail0.40.91.30.91.00.91.00.9-0.91.0-1.0-1.0-1.2-1.2-1.1-1.10.80.9-0.9-0.9-1.0-0.4-0.30.4
Times rat made contact with spout0.60.61.0-0.6-0.7-0.6-0.7-0.70.8-0.80.70.90.90.90.90.9-0.9-0.90.90.71.00.80.8-0.8
Lifetime Intake0.91.02.9-1.0-0.8-0.9-1.1-0.91.0-0.80.70.7-0.10.10.00.2-1.7-1.70.70.80.4-1.4-1.41.4
Liver weight, left0.20.41.2-0.4-0.8-0.4-0.3-0.70.5-0.70.70.61.11.11.01.00.50.50.40.00.4-0.1-0.10.0
Liver weight, right0.20.31.10.50.40.50.60.4-0.50.5-0.4-0.5-0.4-0.3-0.4-0.41.11.1-0.7-0.7-0.7-0.4-0.40.4
Locomotor activity0.00.00.1-0.1-0.1-0.1-0.2-0.10.1-0.10.10.10.20.20.20.1-0.1-0.10.00.20.1-0.1-0.00.0
Locomotor testing distance0.20.41.40.20.20.30.40.3-0.30.3-0.3-0.5-0.5-0.3-0.4-0.50.60.6-0.6-0.5-0.8-1.2-1.21.2
Locomotor testing rearing0.40.61.0-1.0-1.0-0.9-0.9-0.90.8-0.90.90.70.81.00.90.8-0.4-0.40.60.60.4-0.7-0.80.8
Locomotion in novel chamber0.20.20.9-0.30.0-0.4-0.4-0.00.1-0.10.10.30.00.10.10.2-0.4-0.50.40.80.50.90.9-0.9
Locomotion in novel chamber post-restriction2.42.84.1-1.5-1.5-1.6-1.6-1.51.5-1.61.71.81.81.81.81.9-1.5-1.51.91.82.01.61.6-1.6
Fecal boli incidents, locomotor time 10.50.50.80.70.90.70.70.8-0.80.8-0.8-0.7-0.9-0.9-0.8-0.70.60.6-0.6-0.4-0.50.60.6-0.6
Change in fecal boli incidents, locomotor task0.70.71.4-0.8-1.0-0.7-0.8-0.90.9-0.90.80.70.70.60.70.6-0.9-0.90.60.30.3-1.1-1.21.2
Time >=10cm from walls, locomotor time 10.20.21.10.2-0.00.20.20.0-0.00.1-0.1-0.2-0.2-0.3-0.3-0.30.20.2-0.3-0.6-0.5-1.0-1.01.0
Bouts of movement, locomotor time 11.61.72.41.41.51.41.41.5-1.61.5-1.5-1.5-1.3-1.2-1.2-1.41.51.4-1.4-1.1-1.30.30.3-0.3
Total resting periods, locomotor time 11.82.02.91.51.71.51.51.7-1.71.7-1.6-1.5-1.3-1.3-1.3-1.41.61.5-1.4-1.1-1.20.80.8-0.8
Rest time, locomotor task time 11.41.56.21.11.21.01.11.2-1.11.0-0.9-0.7-0.5-0.2-0.2-0.51.11.0-0.5-0.4-0.12.52.5-2.5
Distance moved, locomotor task time 11.51.63.7-1.4-1.5-1.3-1.3-1.41.4-1.31.21.00.90.70.70.9-1.3-1.20.90.80.5-1.9-1.91.9
Vertical activity count, locomotor time 11.01.05.4-0.8-1.0-0.7-0.6-0.90.8-0.80.70.40.40.10.20.4-0.3-0.20.2-0.0-0.3-2.3-2.32.3
Time >=10cm from walls, locomotor time 20.00.10.1-0.3-0.3-0.3-0.2-0.30.2-0.20.30.20.20.20.20.20.00.00.10.20.1-0.3-0.30.3
Bouts of movement, locomotor time 20.50.50.8-0.9-0.8-0.9-0.8-0.80.8-0.80.80.80.70.70.70.7-0.8-0.90.70.80.7-0.1-0.10.1
Total resting periods, locomotor time 20.20.20.5-0.6-0.5-0.6-0.6-0.50.5-0.50.50.50.40.40.40.4-0.6-0.70.50.60.50.10.1-0.1
Rest time, locomotor task time 20.70.81.11.01.01.01.11.0-1.00.9-1.0-0.9-1.0-0.7-0.7-1.00.80.8-0.8-0.9-0.70.70.6-0.6
Distance moved, locomotor task time 20.50.61.2-0.8-0.7-0.8-0.8-0.70.7-0.80.80.81.11.01.11.1-0.3-0.30.70.90.90.60.6-0.6
Vertical activity count, locomotor time 20.30.30.7-0.6-0.8-0.6-0.5-0.60.5-0.60.70.50.80.60.70.80.00.00.30.40.3-0.5-0.50.5
Light reinforcement 10.91.710.3-0.7-1.0-0.6-0.5-0.80.7-0.70.60.20.60.40.50.40.20.2-0.2-0.2-0.6-3.2-3.13.1
Light reinforcement 21.52.012.5-0.1-0.30.10.3-0.1-0.00.1-0.1-0.6-0.6-0.6-0.6-0.70.80.9-0.9-0.9-1.4-3.5-3.43.4
Bone: marrow area0.71.62.6-1.5-1.6-1.5-1.4-1.51.4-1.51.51.31.41.31.31.3-0.9-0.91.11.10.9-1.0-1.00.9
Bone: maximum diameter2.03.75.0-2.2-2.2-2.2-2.1-2.22.1-2.22.22.12.22.12.12.2-1.7-1.72.02.01.90.10.1-0.1
Bone: maximum force2.64.56.2-2.4-2.4-2.4-2.4-2.32.2-2.42.42.32.42.42.42.5-1.8-1.82.22.32.10.20.2-0.2
Bone: maximum moment2.13.65.1-2.2-2.1-2.2-2.1-2.02.0-2.12.12.02.22.22.22.3-1.6-1.61.92.01.90.50.5-0.5
Mean time between licks in bursts0.60.92.70.90.90.91.11.0-1.10.9-0.9-1.0-0.7-0.6-0.6-0.61.61.6-1.1-0.9-0.90.30.3-0.3
Mean num. licks in bursts1.92.33.21.71.81.71.61.7-1.71.7-1.7-1.7-1.7-1.7-1.7-1.71.31.3-1.6-1.5-1.40.20.2-0.2
Cd content in liver0.91.01.5-1.0-1.0-1.1-1.1-0.90.9-1.01.01.01.21.21.21.2-0.7-0.71.01.21.10.80.8-0.8
Co content in liver1.71.93.11.51.31.51.61.4-1.41.4-1.4-1.5-1.4-1.4-1.4-1.41.71.8-1.5-1.7-1.6-0.7-0.70.7
Cu content in liver1.01.22.41.31.11.31.41.2-1.21.1-1.1-1.0-0.6-0.6-0.6-0.61.51.5-1.0-1.2-0.71.11.1-1.0
Fe content in liver0.70.84.20.2-0.10.30.50.1-0.20.2-0.2-0.5-0.4-0.5-0.5-0.50.80.8-0.7-1.0-1.0-2.0-2.02.1
K content in liver0.50.50.80.60.50.60.60.6-0.60.6-0.6-0.7-0.7-0.8-0.8-0.80.70.7-0.8-0.7-0.9-0.8-0.80.8
Mg content in liver0.50.61.10.70.80.70.70.7-0.70.8-0.8-0.8-1.0-1.0-1.0-1.00.60.6-0.7-0.7-0.8-0.3-0.30.3
Mn content in liver0.30.40.7-0.4-0.4-0.5-0.5-0.50.5-0.50.50.60.60.60.60.6-0.5-0.40.70.70.80.80.8-0.9
Na content in liver2.02.14.61.71.41.71.81.5-1.61.5-1.4-1.5-1.1-1.1-1.1-1.12.12.1-1.6-1.9-1.40.10.1-0.1
Rb content in liver4.15.16.42.42.52.42.42.5-2.52.5-2.5-2.5-2.4-2.4-2.4-2.42.42.4-2.5-2.2-2.4-0.3-0.30.4
Se content in liver1.72.13.2-1.5-1.5-1.5-1.4-1.51.5-1.51.61.61.81.81.81.8-1.1-1.01.51.51.60.80.8-0.8
Sr content in liver0.40.30.6-0.6-0.7-0.6-0.5-0.70.7-0.70.80.70.60.60.60.6-0.4-0.40.70.50.70.10.1-0.1
Zn content in liver0.40.40.9-0.5-0.3-0.6-0.6-0.40.4-0.40.40.60.50.50.50.5-0.6-0.60.60.90.80.90.9-0.9
Bone: minimum diameter0.00.00.2-0.00.1-0.0-0.00.1-0.10.1-0.00.00.0-0.1-0.1-0.1-0.1-0.10.10.10.10.50.5-0.5
Time in familiar zone, hab. session 11.11.06.40.20.30.1-0.00.2-0.10.0-0.10.30.20.20.20.2-0.6-0.60.60.40.92.52.5-2.5
Time in novel zone, hab. session 14.14.06.41.61.51.71.91.6-1.81.8-1.7-2.1-1.9-1.8-1.8-1.92.52.5-2.3-2.1-2.5-2.3-2.32.3
Total zone transitions, hab. session 10.00.00.0-0.1-0.1-0.2-0.1-0.10.0-0.10.10.10.10.10.10.1-0.00.00.00.20.10.10.1-0.1
Total locomotion distance, hab. session 10.81.12.1-0.9-0.8-1.0-0.9-0.80.8-0.90.91.01.11.11.11.1-0.7-0.71.11.21.31.41.4-1.4
Locomotion velocity, hab. session 12.02.83.8-1.8-1.6-1.8-1.8-1.61.6-1.71.71.81.91.81.81.8-1.5-1.51.81.91.91.11.1-1.1
Time in familiar zone, hab. session 20.60.73.10.70.70.60.60.7-0.70.6-0.6-0.4-0.2-0.3-0.3-0.20.60.6-0.3-0.30.11.71.7-1.7
Time in novel zone, hab. session 22.32.33.51.31.21.41.41.3-1.31.4-1.4-1.6-1.6-1.6-1.6-1.71.21.2-1.6-1.6-1.9-1.8-1.81.8
Total zone transitions, hab. session 20.40.51.2-0.8-0.8-0.8-0.8-0.80.7-0.70.70.50.60.50.50.5-0.5-0.50.40.60.2-1.1-1.11.1
Total locomotion distance, hab. session 20.81.01.5-1.2-1.1-1.2-1.2-1.11.1-1.11.11.11.11.01.01.0-1.0-1.01.01.21.0-0.0-0.0-0.0
Locomotion velocity, hab. session 21.11.52.1-1.4-1.3-1.4-1.4-1.31.3-1.31.31.31.31.21.21.2-1.3-1.31.31.41.20.10.1-0.1
Novel to familiar place preference ratio4.34.55.92.12.12.22.22.1-2.12.2-2.2-2.3-2.4-2.3-2.3-2.42.02.1-2.3-2.3-2.4-1.3-1.31.3
Novelty place preference5.45.57.32.42.42.52.52.4-2.42.5-2.5-2.6-2.6-2.6-2.6-2.72.32.3-2.6-2.6-2.6-1.1-1.11.1
Time in novel zone, NPP test6.76.98.82.72.72.82.82.7-2.72.8-2.8-2.9-2.9-2.8-2.8-3.02.62.6-2.9-2.9-2.9-1.2-1.21.2
Total zone transitions, NPP test0.50.71.9-0.9-0.9-0.9-0.8-0.90.8-0.80.80.60.70.60.60.6-0.5-0.50.40.60.2-1.4-1.41.3
Total locomotion distance, NPP test1.52.12.9-1.7-1.7-1.7-1.6-1.71.6-1.61.61.41.31.31.31.2-1.5-1.41.31.41.0-1.3-1.31.2
Locomotion velocity, NPP test2.23.14.3-2.1-2.0-2.0-2.0-2.02.0-1.91.91.81.71.61.61.6-1.9-1.91.71.81.4-1.0-1.00.9
Intraocular pressure1.82.63.7-1.9-1.9-1.9-1.8-1.91.9-1.81.81.61.41.41.31.3-1.7-1.71.61.51.2-1.1-1.11.1
Delta distance traveled before/after self-admin0.70.71.80.90.90.91.01.0-1.00.9-0.9-0.9-0.4-0.5-0.5-0.61.31.3-0.9-0.7-0.70.50.5-0.6
Delta ambulatory time before/after self-admin1.71.83.71.51.51.41.61.6-1.61.5-1.4-1.4-0.9-1.0-1.0-1.01.91.9-1.4-1.2-1.20.70.7-0.8
Parametrial fat weight0.10.30.5-0.6-0.6-0.6-0.6-0.50.4-0.50.50.40.70.60.50.6-0.2-0.20.20.50.1-0.7-0.60.6
Pavlov. Cond. lever latency6.58.211.13.33.33.33.23.3-3.23.2-3.2-3.1-3.0-3.1-3.1-3.02.82.8-2.9-2.9-2.60.70.8-0.8
Pavlov. Cond. magazine entry latency0.40.50.8-0.8-0.8-0.8-0.8-0.70.7-0.80.80.80.80.90.90.9-0.5-0.50.70.80.70.30.2-0.2
Pavlov. Cond. change in total contacts2.42.53.4-1.9-1.8-1.8-1.8-1.81.8-1.81.81.71.71.81.81.7-1.5-1.51.61.61.4-0.4-0.50.5
Pavlov. Cond. index score3.03.85.1-2.3-2.2-2.3-2.2-2.22.1-2.22.22.12.12.22.22.2-1.7-1.72.02.11.90.0-0.0-0.0
Pavlov. Cond. latency score2.83.54.8-2.2-2.1-2.2-2.1-2.12.1-2.12.12.02.02.12.12.0-1.7-1.71.92.01.8-0.0-0.10.1
Pavlov. Cond. lever contacts5.16.08.2-2.9-2.8-2.8-2.8-2.82.8-2.72.72.62.52.62.62.5-2.5-2.62.62.62.3-0.4-0.50.4
Pavlov. Cond. magazine entry number0.81.01.51.11.11.11.11.0-1.01.1-1.1-1.1-1.1-1.2-1.2-1.20.80.8-1.0-1.1-1.0-0.3-0.20.2
Pavlov. Cond. intertrial magazine entries0.20.30.4-0.6-0.6-0.6-0.5-0.60.5-0.60.60.60.60.60.60.6-0.4-0.40.50.60.50.20.2-0.2
Pavlov. Cond. lever-magazine prob. diff.3.03.74.8-2.2-2.1-2.2-2.1-2.12.0-2.12.12.12.12.22.22.2-1.7-1.72.02.12.00.40.3-0.4
Pavlov. Cond. response bias3.03.64.9-2.2-2.1-2.2-2.1-2.12.1-2.12.12.02.02.12.12.1-1.8-1.81.92.01.8-0.1-0.20.1
Pavlov. Cond. lever latency3.14.25.52.12.12.22.12.1-2.12.1-2.2-2.3-2.3-2.3-2.3-2.31.71.7-2.2-2.2-2.3-1.4-1.21.2
Pavlov. Cond. magazine entry latency0.40.51.30.80.70.70.80.8-0.80.7-0.7-0.7-0.4-0.3-0.5-0.41.21.2-0.7-0.6-0.50.50.6-0.6
Pavlov. Cond. change in total contacts1.41.94.0-1.1-1.0-1.1-1.1-1.01.0-1.11.21.41.51.61.61.6-0.6-0.61.41.31.62.01.9-2.0
Pavlov. Cond. index score0.50.61.8-0.5-0.5-0.6-0.5-0.50.5-0.60.60.70.80.90.90.9-0.1-0.20.70.70.91.41.3-1.3
Pavlov. Cond. latency score0.70.92.2-0.7-0.7-0.8-0.7-0.70.7-0.70.80.91.01.01.01.0-0.5-0.50.91.01.21.51.5-1.5
Pavlov. Cond. lever contacts1.52.12.7-1.5-1.5-1.6-1.5-1.51.5-1.51.61.61.61.61.61.6-1.1-1.11.61.61.60.90.8-0.8
Pavlov. Cond. magazine entry number0.40.52.70.10.10.20.20.1-0.10.2-0.3-0.4-0.6-0.7-0.6-0.6-0.1-0.1-0.4-0.5-0.7-1.6-1.61.6
Pavlov. Cond. intertrial magazine entries0.40.61.1-0.9-0.8-0.8-0.9-0.80.9-0.80.80.80.60.50.60.6-1.1-1.10.80.70.6-0.4-0.50.4
Pavlov. Cond. lever-magazine prob. diff.0.50.62.0-0.5-0.5-0.5-0.5-0.40.4-0.50.60.70.90.90.90.9-0.1-0.10.70.70.91.41.4-1.4
Pavlov. Cond. response bias0.71.01.5-0.9-0.9-1.0-0.9-0.90.9-0.91.01.01.11.21.21.1-0.5-0.51.01.01.11.11.0-1.0
Time in closed arm before self-admin2.22.43.81.91.81.81.71.8-1.71.8-1.8-1.7-1.9-1.8-1.8-1.71.11.1-1.5-1.7-1.50.20.2-0.1
Time in closed arm after self-admin0.10.10.60.40.30.40.30.2-0.20.2-0.2-0.10.0-0.00.1-0.1-0.0-0.00.0-0.20.10.80.8-0.8
Time in open arm before self-admin1.61.72.7-1.6-1.6-1.5-1.4-1.61.5-1.51.51.31.21.11.21.2-1.1-1.11.11.10.8-1.2-1.21.2
Time in open arm after self-admin1.01.11.8-1.4-1.1-1.3-1.3-1.21.2-1.11.00.90.50.60.50.8-1.1-1.10.81.10.5-1.2-1.21.2
Bone: periosteal estimation1.22.63.8-1.8-1.9-1.8-1.7-1.81.8-1.81.81.71.91.81.81.8-1.3-1.31.61.51.4-0.3-0.30.3
Bone: periosteal perimeter0.30.61.0-0.9-0.9-0.8-0.8-0.90.8-0.80.80.60.80.60.60.6-0.6-0.60.50.50.3-1.0-1.01.0
Bone: post-yield work1.01.32.0-1.4-1.4-1.4-1.2-1.31.2-1.31.31.11.11.11.11.2-0.7-0.70.91.00.7-1.1-1.11.0
Progressive ratio test 1 active lever presses0.50.62.0-0.4-0.3-0.4-0.6-0.40.5-0.30.20.2-0.5-0.4-0.4-0.4-1.4-1.30.30.30.0-1.4-1.41.4
Progressive ratio test 1 breakpoint0.60.62.2-0.6-0.4-0.5-0.7-0.60.7-0.50.40.4-0.3-0.2-0.2-0.2-1.5-1.40.50.40.2-1.4-1.41.4
Progressive ratio test 1 inactive lever presses0.70.84.7-0.5-0.5-0.3-0.4-0.50.5-0.40.20.1-0.4-0.2-0.2-0.3-0.7-0.70.0-0.0-0.4-2.2-2.22.2
Progressive ratio test 2 active lever presses0.50.52.30.00.20.1-0.10.1-0.00.2-0.3-0.3-1.0-0.8-0.9-0.6-0.6-0.5-0.3-0.1-0.5-1.5-1.51.5
Progressive ratio test 2 breakpoint0.50.62.10.20.40.30.10.3-0.20.4-0.5-0.5-1.2-1.0-1.1-0.8-0.4-0.4-0.4-0.3-0.7-1.4-1.41.4
Progressive ratio test 2 inactive lever presses0.20.30.9-0.5-0.4-0.5-0.6-0.50.5-0.40.40.4-0.20.20.10.2-1.0-0.90.50.50.3-0.5-0.50.6
Incentive Sensitization - Responses0.10.10.50.20.20.30.20.2-0.20.2-0.3-0.3-0.4-0.3-0.4-0.30.00.0-0.3-0.4-0.4-0.7-0.70.7
Incentive Sensitization - Breakpoint0.20.20.50.40.30.40.30.3-0.30.4-0.4-0.4-0.6-0.4-0.5-0.40.10.1-0.4-0.5-0.5-0.7-0.70.7
Sum of active levers in priming session hrs 5-63.53.45.41.82.01.81.81.9-1.92.0-2.0-2.0-2.3-2.3-2.2-2.21.51.5-2.0-1.7-2.0-0.9-0.90.9
Progressive ratio0.00.00.10.10.20.10.10.1-0.10.2-0.1-0.2-0.3-0.2-0.2-0.30.00.0-0.2-0.0-0.2-0.3-0.30.3
Food seeking constrained by brief footshock5.87.19.8-3.1-3.1-3.0-3.1-3.13.1-3.02.92.62.32.22.42.3-3.0-2.92.52.52.0-2.0-2.01.9
Seeking ratio, punishment vs. effort1.51.82.6-1.6-1.6-1.5-1.5-1.61.6-1.61.51.41.31.31.31.4-1.4-1.41.41.11.1-0.6-0.60.6
Retroperitoneal fat weight0.10.20.40.50.50.50.60.5-0.50.5-0.5-0.4-0.1-0.1-0.1-0.20.50.5-0.4-0.4-0.20.60.7-0.7
Reaction time number correct0.10.10.7-0.3-0.3-0.3-0.3-0.30.3-0.20.20.2-0.0-0.2-0.10.1-0.4-0.40.10.1-0.0-0.8-0.80.8
Reaction time mean minus median1.72.26.6-1.0-0.8-1.1-1.0-0.80.9-1.01.11.31.51.61.51.5-0.7-0.71.41.51.82.52.6-2.6
Reaction time mean minus median AUC1.92.43.5-1.4-1.3-1.5-1.5-1.31.3-1.41.51.61.71.71.61.7-1.1-1.11.61.81.91.91.8-1.9
Reaction time num false alarms0.10.20.6-0.4-0.2-0.4-0.4-0.20.2-0.20.30.30.10.30.40.2-0.4-0.40.40.60.50.80.8-0.8
Reaction time num false alarms AUC0.40.51.0-0.9-0.7-0.9-0.9-0.70.8-0.70.80.80.50.70.70.6-0.9-0.90.81.00.70.20.1-0.2
Reaction time trials correct on left0.10.10.7-0.3-0.3-0.3-0.3-0.30.3-0.20.20.2-0.0-0.2-0.10.1-0.4-0.40.10.1-0.0-0.8-0.80.8
Reaction time trials on left0.10.10.6-0.2-0.2-0.2-0.2-0.20.2-0.10.10.1-0.1-0.3-0.20.0-0.3-0.30.00.0-0.1-0.8-0.70.7
Reaction time mean1.11.55.61.21.21.11.11.2-1.21.0-1.0-0.7-0.3-0.3-0.3-0.41.41.3-0.7-0.7-0.22.42.3-2.3
Reaction time mean AUC1.21.76.01.31.31.11.21.3-1.31.1-1.0-0.8-0.4-0.4-0.4-0.51.41.3-0.8-0.7-0.32.52.4-2.4
Median of all reaction times2.23.14.72.01.92.02.02.0-2.01.9-1.8-1.7-1.2-1.2-1.2-1.32.22.1-1.7-1.7-1.21.71.6-1.6
Reaction time omissions1.31.72.71.51.51.41.51.5-1.61.5-1.4-1.4-1.1-1.0-1.0-1.11.61.6-1.4-1.2-1.10.70.7-0.7
Reaction time false alarm rate0.10.10.6-0.20.1-0.2-0.10.00.0-0.00.00.1-0.00.20.2-0.0-0.1-0.10.20.40.30.80.7-0.7
Reaction time premature initiation rate1.52.03.51.91.71.81.71.7-1.61.6-1.6-1.3-1.0-1.2-1.1-1.31.21.2-1.2-1.5-0.91.21.3-1.2
Reaction time premature initiations0.91.22.31.51.41.51.31.3-1.21.3-1.3-1.1-0.9-1.1-1.0-1.10.80.9-1.0-1.2-0.80.70.8-0.7
Std. dev. reaction times0.81.27.0-0.00.1-0.2-0.10.1-0.1-0.10.20.40.80.80.80.70.30.30.50.60.92.62.6-2.6
Reaction time trials completed0.10.10.6-0.2-0.2-0.2-0.2-0.20.2-0.10.10.1-0.1-0.3-0.20.0-0.3-0.30.00.0-0.1-0.8-0.70.7
Reaction time trials AUC0.10.10.6-0.2-0.2-0.2-0.2-0.20.2-0.20.10.1-0.1-0.3-0.20.0-0.3-0.30.10.0-0.1-0.7-0.70.7
Run reversals in cocaine runway, females0.20.20.8-0.2-0.3-0.2-0.2-0.20.3-0.30.30.40.40.30.40.6-0.2-0.20.50.10.60.90.9-0.9
Run reversals in cocaine runway, males0.00.00.10.10.10.10.10.1-0.00.1-0.1-0.00.0-0.1-0.1-0.1-0.2-0.20.0-0.00.10.20.2-0.2
Latency to leave start box in cocaine runway0.80.91.6-0.8-1.0-0.8-0.9-1.01.0-1.01.01.01.11.31.11.1-1.1-1.11.00.81.10.40.4-0.4
Latency to leave start box in cocaine runway, F0.00.00.00.10.00.10.10.0-0.00.0-0.1-0.0-0.10.20.1-0.0-0.2-0.2-0.0-0.1-0.1-0.2-0.20.2
Latency to leave start box in cocaine runway, M1.01.01.6-1.1-1.3-1.0-1.0-1.21.1-1.21.11.01.11.11.01.1-0.9-0.90.90.70.8-0.6-0.60.6
Std. dev. time between licks in bursts0.40.40.60.60.70.60.70.8-0.80.8-0.7-0.7-0.8-0.7-0.7-0.70.70.8-0.7-0.6-0.70.20.2-0.2
Total sessions with >9 infusions0.80.94.20.10.20.20.10.1-0.10.3-0.4-0.5-1.1-1.0-1.0-0.8-0.5-0.4-0.5-0.4-0.8-2.0-2.02.0
Short access day 1 total inactive lever presses1.71.94.3-1.4-1.5-1.4-1.5-1.61.6-1.51.41.31.11.21.20.9-2.1-2.01.41.11.1-1.1-1.11.1
Short access day 10 total inactive lever presses0.20.20.8-0.3-0.6-0.3-0.3-0.50.5-0.50.50.50.90.80.80.7-0.2-0.10.40.20.50.10.1-0.1
Short access day 1 total infusions1.11.24.9-0.9-0.9-0.9-0.9-0.91.0-0.80.70.50.00.20.10.1-1.4-1.30.50.50.1-2.2-2.22.2
Short access day 10 total infusions0.70.83.0-0.7-0.6-0.6-0.7-0.70.7-0.50.40.3-0.2-0.1-0.2-0.1-1.2-1.20.40.4-0.0-1.7-1.71.7
Short access total infusions0.70.84.5-0.4-0.2-0.3-0.4-0.30.3-0.10.0-0.1-0.7-0.5-0.6-0.5-0.8-0.8-0.10.0-0.5-2.1-2.12.1
Short access day 1 locomotion0.40.41.50.20.40.20.20.3-0.30.4-0.5-0.5-0.9-0.8-0.8-0.8-0.3-0.3-0.5-0.2-0.6-1.2-1.21.2
Short access day 10 total locomotion0.40.40.80.70.90.60.50.7-0.60.7-0.7-0.5-0.9-0.9-0.8-0.60.10.1-0.4-0.3-0.20.70.7-0.7
Short access total locomotion0.30.31.3-0.2-0.1-0.1-0.2-0.10.2-0.0-0.0-0.1-0.5-0.5-0.5-0.3-0.6-0.6-0.00.0-0.3-1.1-1.11.1
One hour access (0.3 mA shock)0.50.61.4-0.9-0.6-0.8-0.9-0.80.8-0.60.60.5-0.4-0.1-0.20.2-1.2-1.20.60.70.3-1.0-1.01.0
Compulsive drug intake0.20.20.6-0.8-0.6-0.7-0.7-0.60.6-0.50.60.50.20.20.20.3-0.4-0.40.50.70.4-0.2-0.20.1
One hour access (shock baseline)0.50.51.7-0.6-0.5-0.6-0.7-0.60.7-0.50.40.4-0.3-0.1-0.10.1-1.3-1.20.50.50.2-1.2-1.21.2
Social response proportion2.12.34.71.71.61.61.81.7-1.81.6-1.5-1.5-0.9-1.0-1.0-1.12.22.2-1.5-1.4-1.21.21.2-1.1
Social responses0.50.71.4-0.9-0.9-0.9-0.8-0.90.8-0.90.90.91.21.00.91.0-0.5-0.50.80.90.80.00.0-0.0
Social time0.40.52.70.60.40.60.80.6-0.80.6-0.5-0.7-0.1-0.1-0.2-0.11.61.6-0.9-0.7-0.8-0.1-0.10.1
Soleus weight0.72.07.60.60.40.70.80.6-0.70.7-0.7-1.1-1.0-0.9-0.9-0.91.51.5-1.4-1.3-1.8-2.7-2.82.8
Bone: stiffness3.35.17.7-2.7-2.7-2.6-2.5-2.52.4-2.52.62.42.72.72.72.8-1.6-1.62.22.32.20.10.1-0.1
Tibialis anterior weight5.719.627.5-5.1-5.2-5.0-5.0-5.15.0-5.05.04.64.64.74.74.7-4.3-4.34.44.33.8-1.6-1.61.5
Time to tail flick, vehicle, before self-admin0.91.01.51.21.21.21.11.1-1.11.1-1.1-1.0-1.2-1.2-1.2-1.10.60.6-0.9-1.0-0.80.30.3-0.3
Time to tail flick, vehicle, after self-admin0.00.00.10.10.00.10.10.00.00.0-0.1-0.1-0.00.00.0-0.1-0.1-0.1-0.0-0.1-0.0-0.3-0.30.2
Time to tail flick, test, before self-admin0.40.30.6-0.5-0.6-0.5-0.5-0.60.7-0.60.60.70.40.50.50.4-0.8-0.80.80.50.70.60.6-0.4
Time to tail flick, test, after self-admin1.21.22.0-0.9-0.9-1.0-1.1-1.01.1-1.01.01.20.91.00.91.1-1.4-1.41.31.11.40.90.9-1.0
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.3-0.5-0.3-0.2-0.40.4-0.40.40.40.50.60.50.4-0.0-0.00.30.10.3-0.2-0.20.1
Delta time to tail flick, test, before/after SA0.00.00.10.10.20.1-0.00.1-0.10.1-0.1-0.10.10.0-0.00.1-0.1-0.1-0.00.10.10.20.2-0.3
Tibia length0.30.93.30.40.10.50.70.4-0.50.4-0.4-0.7-0.4-0.4-0.4-0.41.31.3-1.0-1.1-1.2-1.8-1.81.8
Ambulatory time before self-admin2.72.84.1-2.0-2.0-1.9-2.0-1.91.9-1.81.81.61.51.51.51.3-1.7-1.81.41.61.1-1.5-1.51.5
Ambulatory time after self-admin0.10.10.3-0.6-0.4-0.5-0.4-0.30.3-0.30.30.20.40.50.40.2-0.0-0.10.10.60.1-0.2-0.20.2
Bone: tissue strength0.10.10.4-0.3-0.3-0.3-0.1-0.20.1-0.20.30.20.50.60.60.60.60.60.10.20.20.40.4-0.4
Total heroin consumption0.80.91.70.80.70.80.80.7-0.70.8-0.9-1.0-1.0-1.0-0.9-1.10.70.7-1.0-1.0-1.2-1.3-1.31.3
Bone: trabecular number1.42.32.9-1.6-1.5-1.6-1.6-1.51.6-1.61.61.71.51.61.61.6-1.6-1.61.71.61.70.70.7-0.7
Bone: trabecular spacing0.10.10.80.00.0-0.0-0.00.00.0-0.10.10.20.30.20.20.2-0.1-0.10.20.20.40.90.9-0.9
Bone: trabecular thickness0.10.10.20.20.30.20.20.3-0.20.3-0.3-0.2-0.4-0.3-0.3-0.30.20.2-0.2-0.1-0.20.20.2-0.2
Bone: trabecular tissue density1.82.54.2-1.8-2.0-1.8-1.7-1.81.7-1.81.91.72.12.02.02.0-0.8-0.81.51.61.4-0.3-0.30.2
Water consumed over 24 hours0.91.01.5-1.0-1.1-1.0-1.1-1.11.1-1.11.01.11.11.11.11.1-1.2-1.21.11.01.10.20.2-0.2
Number of responses in last shaping day0.91.06.1-0.0-0.10.10.1-0.10.00.1-0.2-0.4-0.5-0.3-0.3-0.60.10.2-0.6-0.5-0.9-2.5-2.52.5