Hub : Genes

Fabp12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Fabp12 0.1 0.07 5.9e-09 0.06 0.04 0.05 0.05 7.1e-07 8.3e-06 6.3e-06 3.5e-06
2 RMTg gene expression Fabp12 0.15 0.13 5.0e-03 0.06 0.04 0.03 0.05 1.1e-02 3.0e-02 6.5e-02 2.1e-02
3 NAcc gene expression Fabp12 0.08 0.06 1.6e-08 0.05 0.04 0.04 0.05 9.7e-08 1.8e-06 3.1e-07 1.1e-07
4 Liver intron excision ratio chr2_93410626_93419071 0.65 0.13 0.0e+00 0.45 0.45 0.46 0.46 8.7e-56 4.5e-55 4.2e-56 1.9e-56
5 Eye intron excision ratio chr2_93408057_93419071 0.8 0.11 8.9e-10 0.41 0.36 0.32 0.42 2.1e-07 1.8e-06 7.4e-06 1.2e-07
6 Eye intron excision ratio chr2_93458436_93460630 0.72 0.14 3.4e-08 0.35 0.36 0.4 0.41 2.2e-06 1.8e-06 3.0e-07 2.3e-07
7 pVTA gene expression Fabp12 0.17 0.08 4.4e-16 0.19 0.16 0.18 0.11 7.1e-15 1.0e-12 8.2e-15 3.7e-09
8 Eye intron excision ratio chr2_93408057_93449086 0.25 0.16 8.6e-03 0.12 0.07 0.04 0.09 6.7e-03 3.5e-02 7.0e-02 2.0e-02
9 Eye intron excision ratio chr2_93408057_93456552 0.71 0.15 2.7e-07 0.29 0.34 0.34 0.35 2.3e-05 4.0e-06 4.0e-06 2.4e-06
10 Liver intron excision ratio chr2_93410626_93456552 0.46 0.17 0.0e+00 0.29 0.26 0.28 0.28 2.0e-32 3.6e-29 1.0e-30 5.7e-31
11 Liver intron excision ratio chr2_93458436_93460630 0.49 0.14 0.0e+00 0.34 0.34 0.35 0.35 3.1e-39 1.6e-38 4.8e-40 1.1e-39
12 Eye gene expression Fabp12 0.55 0.19 2.7e-05 0.17 0.2 0.23 0.21 1.6e-03 5.3e-04 1.8e-04 3.8e-04
13 BLA gene expression Fabp12 0.11 0.07 2.0e-04 0.05 0.06 0.06 0.04 1.6e-03 6.7e-04 2.3e-04 2.0e-03
14 Eye intron excision ratio chr2_93456672_93458264 0.73 0.14 4.7e-08 0.38 0.36 0.36 0.37 5.5e-07 1.9e-06 1.8e-06 1.2e-06
15 Liver intron excision ratio chr2_93456672_93458264 0.45 0.15 0.0e+00 0.32 0.32 0.33 0.32 7.5e-37 1.0e-35 1.0e-37 9.8e-37
16 BLA alternative TSS NM_001134614.1 0.06 0.05 7.9e-03 0.04 0.01 0.02 0.01 5.4e-03 5.8e-02 1.9e-02 1.4e-01
17 BLA alternative TSS XM_006232145.5 0.06 0.05 8.1e-03 0.04 0.01 0.02 0.01 5.7e-03 6.3e-02 2.3e-02 1.3e-01
18 Liver gene expression Fabp12 0.72 0.16 0.0e+00 0.44 0.45 0.48 0.47 3.4e-54 1.1e-55 3.2e-60 1.5e-57
19 Adipose mRNA stability Fabp12 0.02 0.02 1.0e-02 0 -0 0 0 2.1e-01 4.1e-01 2.2e-01 3.2e-01
20 Liver alternative TSS NM_001134614.1 0.04 0.03 2.9e-03 0.01 0.01 0 0.01 6.7e-03 6.7e-03 1.5e-01 8.5e-03
21 Adipose alternative TSS NM_001134614.1 0.03 0.03 8.8e-03 0.02 0.01 0.01 0.01 6.4e-03 2.3e-02 2.9e-02 2.6e-02
22 Adipose alternative TSS XM_006232145.5 0.04 0.03 5.9e-03 0.02 0.01 0.01 0.01 4.6e-03 1.5e-02 2.1e-02 2.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.83.03.81.42.02.0-1.9-1.91.91.81.91.91.81.81.91.91.71.7-1.71.71.71.71.7-0.80.8
Area under the delay curve1.01.21.6-1.0-1.2-1.11.21.1-1.1-1.2-1.2-1.0-1.2-1.2-1.2-0.8-1.3-1.21.1-1.1-1.1-1.1-1.20.5-0.5
BMI with tail0.41.32.1-1.5-1.4-1.41.31.2-1.2-1.2-1.2-1.2-1.4-1.3-1.2-1.3-1.0-1.21.0-1.0-1.0-1.1-0.6-0.40.4
BMI without tail0.51.73.5-1.9-1.4-1.41.51.4-1.3-1.1-1.5-1.2-1.4-1.6-1.2-1.5-1.0-1.41.0-1.0-1.5-0.8-0.5-0.90.9
Body weight0.31.45.6-2.4-1.1-1.11.21.0-1.0-0.9-1.1-0.8-1.0-1.5-0.8-1.1-0.7-1.10.6-0.6-1.1-0.30.1-1.91.9
Weight adjusted by age0.10.20.4-0.6-0.3-0.3-0.4-0.40.4-0.10.60.30.60.30.2-0.3-0.10.50.1-0.10.40.20.4-0.60.6
Bone surface4.48.09.71.82.92.9-3.0-3.13.12.83.13.13.02.83.12.92.92.8-2.92.92.73.03.0-1.91.9
Bone volume4.27.69.11.63.03.0-2.9-3.03.02.83.03.03.02.73.02.92.72.8-2.62.62.62.92.9-2.02.0
Breakpoint value in progressive ratio session0.20.31.0-0.9-0.4-0.40.40.2-0.2-0.5-0.4-0.0-0.3-0.5-0.2-0.5-0.5-0.50.5-0.5-0.80.1-0.0-1.01.0
Number of licking bursts0.30.50.70.80.90.8-0.8-0.80.80.80.70.80.70.70.80.80.70.7-0.80.80.70.70.7-0.30.3
Context. condit. distance diff. score0.30.40.6-0.1-0.7-0.70.70.7-0.7-0.6-0.7-0.6-0.7-0.6-0.5-0.6-0.4-0.70.4-0.4-0.6-0.6-0.70.7-0.7
Locomotion velocity, session 11.51.62.8-1.7-1.4-1.41.41.3-1.3-1.5-1.3-1.2-1.2-1.4-1.2-1.4-1.2-1.31.2-1.2-1.3-0.9-0.7-0.70.7
Locomotion distance, session 10.30.41.7-1.3-0.4-0.40.50.4-0.3-0.4-0.4-0.3-0.4-0.7-0.2-0.4-0.3-0.50.3-0.3-0.60.10.3-1.31.3
Locomotion velocity, session 21.31.52.9-1.7-1.3-1.31.41.3-1.3-1.2-1.3-1.2-1.2-1.4-1.2-1.3-1.3-1.21.4-1.4-1.3-0.8-0.7-0.80.8
Locomotion distance, session 20.40.53.8-1.5-0.1-0.10.40.2-0.2-0.1-0.3-0.1-0.2-0.5-0.0-0.2-0.2-0.30.3-0.3-0.50.40.7-1.91.9
Locomotion velocity, session 30.00.00.1-0.1-0.2-0.20.20.2-0.2-0.2-0.2-0.2-0.1-0.1-0.2-0.1-0.2-0.10.2-0.2-0.2-0.3-0.20.1-0.1
Locomotion distance, session 30.60.70.90.50.90.9-0.8-0.90.90.90.90.90.90.80.90.90.80.8-0.80.80.80.80.9-0.50.5
Stereotopy head waving bouts, day 30.40.51.8-0.30.60.6-0.5-0.70.70.50.70.60.60.40.70.60.50.5-0.50.50.40.90.9-1.31.3
Stereotopy head waving duration, day 30.20.20.5-0.7-0.4-0.40.40.4-0.4-0.5-0.3-0.4-0.4-0.5-0.4-0.5-0.5-0.40.5-0.5-0.5-0.1-0.2-0.50.5
Locomotion velocity, session 78.49.111.92.13.23.2-3.0-3.23.23.32.93.33.12.83.53.23.42.8-3.33.32.63.33.3-2.02.0
Locomotion distance, session 74.45.67.32.52.62.6-2.4-2.52.52.72.32.62.52.42.72.72.72.3-2.62.62.12.42.1-0.30.3
Stereotopy head waving bouts, day 70.20.30.9-1.0-0.4-0.40.50.5-0.5-0.5-0.4-0.5-0.5-0.6-0.4-0.5-0.5-0.40.5-0.5-0.5-0.2-0.1-0.80.8
Stereotopy head waving duration, day 70.70.91.4-1.2-1.0-1.01.01.0-1.0-1.1-0.9-1.0-1.0-1.0-1.0-1.1-1.0-0.90.9-0.9-0.9-0.8-0.6-0.30.3
Locomotion velocity, session 83.13.75.3-2.3-2.1-2.12.22.1-2.1-2.1-2.1-2.0-2.0-2.1-2.0-2.1-2.0-2.02.0-2.0-2.0-1.6-1.4-0.20.2
Locomotion distance, session 80.71.02.0-1.4-1.1-1.11.21.1-1.0-1.0-1.2-0.9-1.1-1.3-0.7-0.9-0.8-1.20.8-0.8-1.2-0.5-0.4-0.60.6
Degree of sensitization distance0.20.20.40.60.50.5-0.4-0.50.50.60.40.60.40.40.60.50.70.4-0.50.50.30.60.40.1-0.1
Degree of sensitization stereotypy1.01.12.1-1.4-1.0-1.01.11.1-1.1-1.1-1.0-1.1-1.1-1.1-1.1-1.2-1.1-1.01.1-1.1-1.0-0.8-0.6-0.50.5
Conditioned locomotion0.10.10.2-0.4-0.3-0.20.20.2-0.2-0.2-0.2-0.3-0.3-0.3-0.3-0.2-0.3-0.30.3-0.3-0.2-0.2-0.1-0.30.3
Cocaine response after cond. corrected0.30.30.80.90.50.5-0.6-0.60.60.50.60.60.50.60.60.60.70.5-0.60.60.60.30.30.6-0.6
Cocaine response after cond. not corrected0.70.81.51.20.90.9-1.0-1.01.00.91.00.90.91.00.91.01.01.0-0.90.91.00.60.50.6-0.6
Cocaine response before conditioning0.50.60.80.40.80.8-0.8-0.80.80.90.80.80.90.80.80.90.70.9-0.70.70.80.70.8-0.40.4
Saline control response1.41.92.60.51.41.4-1.4-1.51.51.51.51.51.41.31.51.41.31.3-1.31.31.21.51.6-1.31.3
Bone: connectivity density1.72.73.71.71.81.8-1.7-1.81.81.71.71.81.71.61.81.71.91.6-1.91.91.51.51.5-0.40.4
Bone: cortical apparent density1.11.52.0-1.0-1.2-1.21.41.4-1.4-1.4-1.4-1.3-1.3-1.3-1.4-1.3-1.3-1.21.3-1.3-1.3-1.2-1.20.2-0.2
Bone: cortical area0.40.61.8-0.60.60.6-0.8-0.80.80.60.90.70.90.60.70.60.30.7-0.30.30.71.01.1-1.41.4
Bone: cortical porosity0.40.40.60.10.70.7-0.7-0.70.70.70.80.60.70.70.60.60.50.7-0.50.50.70.70.8-0.60.6
Bone: cortical porosity0.20.20.5-0.20.50.5-0.4-0.50.50.50.50.40.50.40.40.40.20.4-0.20.20.40.60.6-0.70.7
Bone: cortical thickness0.20.32.3-1.20.10.1-0.2-0.30.30.10.30.20.30.00.30.1-0.20.20.2-0.20.10.60.7-1.51.5
Bone: cortical thickness1.92.35.7-2.4-1.4-1.41.41.4-1.4-1.6-1.3-1.6-1.3-1.5-1.5-1.5-2.0-1.32.0-2.0-1.4-0.9-0.8-0.90.9
Bone: cortical tissue density1.21.62.1-1.0-1.3-1.31.41.4-1.4-1.4-1.5-1.4-1.4-1.3-1.4-1.3-1.3-1.31.3-1.3-1.3-1.3-1.20.3-0.3
Condit. Reinf. active minus inactive responses1.21.48.2-2.5-0.5-0.50.70.5-0.5-0.4-0.5-0.4-0.5-1.0-0.3-0.6-0.7-0.70.7-0.7-0.80.50.8-2.92.9
Condit. Reinf. active-inactive response ratio1.61.78.9-2.8-0.7-0.71.00.7-0.7-0.7-0.7-0.6-0.7-1.2-0.5-0.8-0.8-0.90.8-0.8-1.00.40.7-3.03.0
Condit. Reinf. active responses1.01.29.1-2.3-0.1-0.10.30.0-0.0-0.1-0.0-0.0-0.1-0.60.1-0.2-0.4-0.30.4-0.4-0.40.81.1-3.03.0
Condit. Reinf. inactive responses0.10.10.2-0.30.30.2-0.3-0.30.30.10.30.20.30.20.20.20.10.2-0.00.00.20.30.3-0.50.5
Incentive salience index mean1.21.59.2-2.7-0.6-0.50.70.4-0.4-0.5-0.4-0.4-0.5-1.0-0.3-0.6-0.7-0.70.7-0.7-0.80.50.9-3.03.0
Condit. Reinf. lever presses0.60.93.5-1.9-0.8-0.80.80.6-0.6-0.8-0.6-0.6-0.6-1.0-0.5-0.8-0.6-0.80.7-0.7-0.8-0.10.2-1.81.8
Condit. Reinf. active minus inactive responses5.26.78.51.22.72.7-2.6-2.82.82.62.72.82.82.42.92.62.62.6-2.62.62.32.92.9-2.02.0
Condit. Reinf. active-inactive response ratio3.23.75.20.72.02.0-1.9-2.12.11.92.02.12.01.72.12.01.91.9-1.91.91.62.32.2-1.81.8
Condit. Reinf. active responses6.59.011.21.63.13.2-3.1-3.23.23.03.23.23.32.93.33.13.13.0-3.03.02.73.33.3-2.12.1
Condit. Reinf. inactive responses0.50.60.80.40.80.8-0.8-0.90.90.80.90.80.90.70.90.80.80.8-0.80.80.70.90.9-0.60.6
Condit. Reinf. lever presses2.94.04.91.12.22.2-2.0-2.12.12.12.12.22.01.82.22.12.11.8-2.12.11.82.22.2-1.51.5
Condit. Reinf. lever reinforcers received6.69.211.21.63.23.2-3.1-3.33.33.13.33.33.32.93.33.13.13.1-3.13.12.83.33.3-2.12.1
Conditioned reinforcement - actives4.67.810.92.83.33.2-2.7-2.93.03.32.63.32.72.63.12.73.32.5-3.33.32.42.62.7-0.80.8
Conditioned reinforcement - inactives0.60.81.30.80.70.7-1.1-1.11.10.51.11.11.10.91.00.70.81.0-0.80.80.81.00.9-0.60.6
Conditioned locomotion2.93.85.92.22.12.0-1.9-2.02.02.31.82.21.71.82.11.82.41.8-2.42.41.91.62.0-0.60.6
Patch foraging indifference point 0 sec0.20.41.41.20.60.6-0.7-0.50.50.50.50.40.70.70.30.70.30.7-0.30.30.60.1-0.11.0-1.0
Patch foraging indifference point AUC0.30.51.0-0.6-0.7-0.80.60.7-0.7-0.7-0.6-0.7-0.6-0.6-0.7-1.0-0.7-0.60.8-0.8-0.6-0.7-0.70.3-0.3
Delay disc. indifference point, 0s delay0.10.10.30.4-0.00.00.10.3-0.30.0-0.1-0.5-0.2-0.0-0.30.10.2-0.0-0.20.20.2-0.6-0.20.5-0.5
Delay disc. indifference point, 16s delay0.80.91.5-0.9-1.0-0.91.10.9-0.9-1.0-1.0-0.8-1.1-1.1-0.9-0.8-1.1-1.21.0-1.0-1.2-0.6-1.00.5-0.5
Delay disc. indifference point, 2s delay0.30.32.7-0.90.10.10.1-0.00.00.10.00.1-0.1-0.30.20.30.0-0.1-0.10.1-0.10.50.7-1.61.6
Delay disc. indifference point, 24s delay0.20.20.4-0.4-0.3-0.30.40.4-0.4-0.3-0.4-0.3-0.3-0.4-0.4-0.4-0.6-0.50.5-0.5-0.6-0.3-0.60.4-0.4
Delay disc. indifference point, 4s delay1.92.03.2-1.4-1.7-1.71.51.4-1.4-1.8-1.5-1.2-1.6-1.5-1.5-1.4-1.7-1.51.5-1.5-1.3-1.4-1.40.3-0.3
Delay disc. indifference point, 8s delay0.40.41.0-0.1-0.7-0.70.50.5-0.5-0.7-0.5-0.5-0.5-0.4-0.7-0.0-0.9-0.40.8-0.8-0.3-1.0-1.00.9-0.9
Indifference point function ln k0.10.10.3-0.0-0.3-0.20.50.4-0.4-0.2-0.5-0.3-0.5-0.4-0.3-0.2-0.1-0.50.1-0.1-0.5-0.2-0.30.3-0.3
Indifference point function log k0.10.10.3-0.0-0.3-0.20.50.4-0.4-0.2-0.5-0.3-0.5-0.4-0.3-0.2-0.1-0.50.1-0.1-0.5-0.2-0.30.3-0.3
Patch foraging total patch changes 0 sec0.10.21.30.80.20.2-0.3-0.10.10.10.2-0.00.30.4-0.10.3-0.20.20.1-0.10.2-0.2-0.51.2-1.2
Patch foraging total patch changes 12 sec0.10.10.90.5-0.1-0.2-0.20.0-0.0-0.20.1-0.20.00.3-0.2-0.2-0.20.20.2-0.20.3-0.5-0.50.9-0.9
Patch foraging total patch changes 18 sec0.50.81.5-0.9-0.9-0.90.80.9-0.9-0.9-0.8-1.0-0.7-0.8-1.0-1.0-1.2-0.81.2-1.2-0.8-0.7-0.90.3-0.3
Patch foraging total patch changes 24 sec0.20.30.80.1-0.5-0.40.60.6-0.6-0.4-0.6-0.6-0.7-0.5-0.6-0.3-0.4-0.50.4-0.4-0.3-0.9-0.80.9-0.9
Patch foraging total patch changes 6 sec0.20.40.8-0.1-0.6-0.60.40.6-0.6-0.7-0.5-0.7-0.4-0.3-0.7-0.3-0.9-0.30.8-0.8-0.3-0.7-0.90.7-0.7
Patch foraging time to switch 0 sec0.30.64.1-1.4-0.1-0.10.3-0.00.00.0-0.20.2-0.1-0.40.40.1-0.0-0.3-0.00.0-0.40.91.0-2.02.0
Patch foraging water rate 0 sec0.30.61.70.2-0.6-0.60.40.7-0.7-0.9-0.5-0.9-0.6-0.4-1.0-0.8-0.8-0.50.8-0.8-0.4-1.0-1.21.3-1.3
Patch foraging water rate 12 sec0.51.01.91.41.11.2-1.1-1.01.01.01.10.80.91.20.81.20.90.9-1.01.01.00.60.31.0-1.0
Patch foraging water rate 18 sec0.20.30.90.70.70.7-0.7-0.60.60.50.70.50.40.60.40.90.60.5-0.60.60.70.30.30.4-0.4
Patch foraging water rate 24 sec0.60.92.30.1-0.7-0.70.80.9-0.9-0.7-1.0-0.9-0.9-0.8-1.0-0.6-0.8-0.80.8-0.8-0.9-1.0-1.31.5-1.5
Patch foraging water rate 6 sec1.01.43.31.81.11.2-1.4-1.21.21.21.31.21.31.41.11.11.21.3-1.11.11.20.80.60.8-0.8
Seeking ratio, delayed vs. immediate footshock4.45.410.93.32.42.4-2.8-2.52.52.32.72.32.42.92.22.42.32.5-2.32.32.81.31.30.9-0.9
Distance traveled before self-admin0.50.61.2-0.7-1.0-1.00.90.7-0.7-1.1-0.9-0.5-0.9-0.9-0.7-0.9-0.7-0.90.8-0.8-0.7-0.8-0.6-0.10.1
Distance traveled after self-admin0.00.00.20.3-0.0-0.0-0.10.1-0.1-0.10.0-0.20.10.1-0.0-0.00.10.10.0-0.00.1-0.0-0.20.4-0.4
Extensor digitorum longus weight6.124.047.5-6.9-5.3-5.35.75.1-5.1-5.1-5.3-4.8-5.4-5.9-4.5-5.2-4.7-5.44.6-4.6-5.4-3.0-2.7-2.42.4
Bone: elastic displacement0.70.82.3-0.20.80.8-0.7-0.90.90.90.80.90.70.61.00.80.90.7-0.90.90.61.11.3-1.51.5
Bone: elastic work1.11.42.7-0.01.11.1-1.0-1.21.21.21.21.21.20.91.31.11.11.0-1.11.11.01.41.6-1.61.6
Bone: endosteal estimation1.73.75.20.81.91.9-1.9-2.12.12.02.02.11.91.72.11.92.01.8-2.02.01.72.22.3-1.81.8
Bone: endosteal perimeter0.61.31.70.91.11.1-1.3-1.31.31.31.31.31.21.21.31.21.21.1-1.21.21.21.21.2-0.50.5
Epididymis fat weight0.51.73.0-1.2-1.4-1.51.61.4-1.4-1.0-1.6-1.2-1.7-1.6-1.3-1.6-0.9-1.70.9-0.9-1.5-1.3-1.00.4-0.4
Delta time in closed arm before/after self-admin0.40.31.40.3-0.3-0.30.50.7-0.8-0.2-0.6-0.9-0.6-0.3-0.7-0.2-0.2-0.30.1-0.1-0.0-1.2-0.60.9-0.9
Delta time in open arm before/after self-admin0.40.40.80.30.50.5-0.6-0.80.80.50.70.90.70.60.80.60.50.6-0.40.40.30.90.5-0.30.3
Diff in mean of infusions in LGA sessions0.40.42.2-1.40.20.20.40.0-0.00.1-0.20.1-0.2-0.60.2-0.4-0.3-0.50.2-0.2-0.91.00.6-1.51.5
Delay discount exponential model param0.80.91.40.81.11.0-1.0-1.00.91.11.00.91.11.01.00.71.21.0-1.11.11.01.01.1-0.40.4
Extinction: sum of active levers before priming0.10.10.7-0.50.20.2-0.4-0.30.30.20.50.20.50.30.2-0.10.00.40.1-0.10.20.20.4-0.90.9
Active lever presses in extinction session 60.10.10.60.3-0.0-0.00.10.1-0.1-0.0-0.1-0.1-0.1-0.0-0.2-0.4-0.2-0.10.2-0.2-0.2-0.3-0.50.8-0.8
Bone: final force0.40.62.2-0.60.60.6-0.7-0.80.80.70.80.70.80.50.70.50.40.6-0.40.40.61.01.2-1.51.5
Bone: final moment0.61.02.0-0.30.90.9-1.0-1.11.11.01.11.01.10.81.00.90.70.9-0.70.70.91.31.4-1.41.4
Food consumed during 24 hour testing period0.60.92.6-1.6-1.0-1.00.90.8-0.9-1.0-0.8-0.9-0.8-1.0-0.8-1.0-1.0-0.81.0-1.0-0.9-0.4-0.3-1.01.0
Glucose0.50.82.1-1.4-1.0-1.10.80.8-0.8-1.0-0.7-0.9-0.7-0.8-0.8-1.0-1.2-0.71.2-1.2-0.8-0.5-0.4-0.60.6
Heart weight0.71.11.4-0.7-1.0-1.11.11.2-1.2-1.1-1.1-1.2-1.0-1.0-1.2-0.8-1.0-1.01.2-1.2-0.9-1.1-1.10.5-0.5
Delay discount hyperbolic model param0.91.01.61.11.21.1-1.1-1.01.01.11.10.91.11.11.10.81.31.1-1.11.11.10.91.0-0.00.0
Intermittent access intake day 1-15 change1.32.64.52.12.01.8-1.8-1.71.72.01.71.61.71.81.51.31.61.7-1.61.61.61.11.00.4-0.4
Intermittent access intake escalation1.22.45.62.41.91.7-1.7-1.61.62.01.51.61.61.81.51.21.61.6-1.61.61.40.90.70.8-0.8
Intermittent access intake escalation 23.84.47.92.82.32.1-2.4-2.22.22.42.32.12.42.52.01.92.12.4-2.12.12.31.51.30.6-0.6
Intermitt. access day 1 inactive lever presses1.24.66.5-1.3-2.3-2.32.42.5-2.6-2.2-2.5-2.6-2.2-2.2-2.3-2.5-2.0-2.12.0-2.0-2.2-2.0-2.00.9-0.9
Intermitt. access day 15 inactive lever presses1.42.94.3-0.6-1.7-1.71.51.7-1.8-1.9-1.6-1.9-1.5-1.3-1.8-1.8-1.9-1.51.8-1.8-1.4-1.7-2.11.9-1.9
Intermitt. access escalation Index1.82.63.7-0.9-1.5-1.21.51.7-1.8-1.8-1.6-1.9-1.7-1.4-1.7-1.3-1.8-1.61.9-1.9-1.4-1.4-1.81.4-1.4
Intermittent access day 1 total infusions3.04.96.81.72.42.6-2.5-2.62.62.22.62.52.52.52.42.41.92.4-2.02.02.32.12.0-0.50.5
Intermittent access day 15 total infusions5.48.111.23.23.33.4-3.2-3.23.23.23.13.23.03.23.03.02.72.9-2.82.82.82.42.00.4-0.4
Intermittent access terminal intake (last 3 days)6.78.811.93.23.33.3-3.5-3.33.33.23.43.23.33.43.03.32.63.2-2.72.73.12.52.10.4-0.4
Intermittent access total infusions5.26.28.42.62.92.9-2.8-2.82.82.72.82.82.72.82.62.72.32.6-2.32.32.62.01.90.1-0.1
Intermittent access day 1 locomotion1.11.42.30.91.31.5-1.4-1.41.40.91.51.31.41.31.31.50.71.3-0.70.71.21.30.90.0-0.0
Intermittent access day 15 total locomotion1.12.03.11.11.61.8-1.7-1.51.51.51.71.31.61.71.41.41.21.6-1.21.21.51.31.3-0.50.5
Intermittent access total locomotion2.22.64.11.51.81.9-2.0-1.81.81.72.01.52.02.01.61.71.21.9-1.31.31.81.41.30.0-0.0
Intermittent access standard deviation1.32.87.42.71.81.8-1.8-1.71.71.81.61.81.51.91.51.51.71.6-1.71.71.80.70.61.2-1.2
Left kidney weight0.10.31.10.2-0.7-0.80.20.4-0.5-0.7-0.3-0.6-0.2-0.2-0.6-0.5-0.4-0.20.5-0.5-0.1-0.6-0.81.1-1.1
Right kidney weight0.10.61.2-0.7-1.0-1.10.50.7-0.7-1.1-0.5-0.9-0.5-0.6-0.8-0.8-0.9-0.51.0-1.0-0.5-0.6-0.80.4-0.4
Cocaine induced anxiety0.50.71.2-0.7-0.8-0.90.90.8-0.8-1.0-0.9-0.7-0.7-0.8-0.9-0.9-1.1-0.71.1-1.1-1.0-0.8-0.90.4-0.4
Post-drug Anxiety1.31.42.6-1.4-0.9-1.01.51.3-1.2-1.1-1.5-1.0-1.4-1.6-1.1-1.3-1.0-1.41.0-1.0-1.6-0.8-0.7-0.50.5
Baseline Anxiety0.20.21.0-0.50.30.30.10.1-0.10.4-0.1-0.1-0.2-0.20.1-0.60.4-0.2-0.40.4-0.10.20.6-1.01.0
Tail length0.20.73.2-1.8-0.6-0.60.90.8-0.7-0.6-0.9-0.6-0.7-1.2-0.5-0.7-0.6-0.80.6-0.6-1.10.0-0.0-1.11.1
Length with tail0.10.53.1-1.6-0.2-0.20.40.2-0.2-0.1-0.3-0.1-0.2-0.70.0-0.3-0.1-0.30.1-0.1-0.50.50.5-1.71.7
Length without tail0.30.81.50.20.80.8-0.8-0.90.90.90.90.80.90.70.90.91.00.8-1.01.00.90.91.0-1.21.2
Times rat made contact with spout0.10.10.10.20.30.4-0.3-0.30.30.10.30.20.30.40.20.30.10.3-0.20.20.30.20.10.2-0.2
Lifetime Intake3.23.95.92.42.32.3-2.3-2.22.22.12.22.22.12.31.92.21.72.1-1.71.72.21.41.20.6-0.6
Liver weight, left0.10.10.8-0.9-0.2-0.20.10.0-0.0-0.1-0.0-0.0-0.1-0.3-0.0-0.3-0.1-0.20.2-0.2-0.20.30.3-0.90.9
Liver weight, right0.71.22.0-0.5-1.2-1.10.91.1-1.1-1.2-1.0-1.3-0.9-0.8-1.3-1.3-1.2-0.91.2-1.2-0.8-1.3-1.41.1-1.1
Locomotor activity0.00.00.0-0.1-0.1-0.0-0.0-0.10.1-0.00.10.10.00.10.0-0.10.10.10.0-0.00.1-0.10.0-0.20.2
Locomotor testing distance0.00.00.3-0.20.10.1-0.1-0.20.20.10.10.20.20.10.2-0.00.10.2-0.10.1-0.00.20.3-0.50.5
Locomotor testing rearing0.40.81.50.91.11.0-1.1-1.00.90.91.00.81.11.20.80.80.71.2-0.70.71.00.40.50.2-0.2
Locomotion in novel chamber0.10.20.9-0.9-0.1-0.10.20.1-0.1-0.1-0.1-0.0-0.1-0.3-0.1-0.6-0.2-0.20.1-0.1-0.2-0.00.4-0.90.9
Locomotion in novel chamber post-restriction0.20.30.6-0.1-0.4-0.30.40.6-0.6-0.4-0.5-0.7-0.4-0.3-0.6-0.0-0.5-0.30.5-0.5-0.1-0.8-0.60.8-0.8
Fecal boli incidents, locomotor time 10.10.10.4-0.6-0.4-0.30.30.2-0.2-0.4-0.3-0.2-0.1-0.3-0.20.2-0.4-0.20.4-0.4-0.30.0-0.1-0.20.2
Change in fecal boli incidents, locomotor task1.81.83.41.81.41.4-1.5-1.61.61.41.51.61.31.61.30.91.51.4-1.31.31.60.70.80.3-0.3
Time >=10cm from walls, locomotor time 11.92.13.71.21.51.6-1.6-1.61.61.41.61.51.51.61.41.61.51.6-1.51.51.91.01.3-0.50.5
Bouts of movement, locomotor time 12.12.46.00.3-1.4-1.21.31.5-1.5-1.3-1.4-1.6-1.6-0.9-1.7-1.0-1.3-1.21.3-1.3-0.7-2.3-2.12.5-2.5
Total resting periods, locomotor time 11.21.33.90.4-1.0-0.80.91.1-1.1-0.9-1.1-1.1-1.2-0.6-1.3-0.8-0.9-0.80.9-0.9-0.4-1.9-1.62.0-2.0
Rest time, locomotor task time 10.30.41.30.4-0.5-0.40.50.6-0.7-0.4-0.6-0.7-0.6-0.2-0.7-0.7-0.3-0.30.4-0.4-0.0-1.2-0.80.9-0.9
Distance moved, locomotor task time 10.00.00.1-0.3-0.0-0.10.1-0.00.0-0.0-0.00.1-0.1-0.20.10.30.1-0.2-0.00.0-0.20.30.1-0.20.2
Vertical activity count, locomotor time 10.30.81.8-0.10.80.7-0.6-0.90.90.90.71.00.60.41.01.20.80.4-0.90.90.41.31.2-1.31.3
Time >=10cm from walls, locomotor time 21.21.82.50.61.31.4-1.4-1.41.41.31.51.31.61.31.41.01.41.5-1.41.41.61.31.5-1.01.0
Bouts of movement, locomotor time 21.93.05.2-0.5-1.8-1.61.71.7-1.7-1.9-1.8-1.6-1.8-1.4-2.0-1.5-1.7-1.51.7-1.7-1.3-2.3-2.21.9-1.9
Total resting periods, locomotor time 21.83.25.9-0.5-1.9-1.71.71.7-1.7-1.9-1.8-1.6-1.9-1.5-2.0-1.5-1.8-1.61.8-1.8-1.3-2.4-2.42.0-2.0
Rest time, locomotor task time 20.60.71.5-0.3-0.9-0.80.80.8-0.8-0.8-0.9-0.7-0.9-0.7-1.0-0.9-1.1-0.81.0-1.0-0.6-1.2-1.10.7-0.7
Distance moved, locomotor task time 20.00.10.2-0.1-0.2-0.50.10.3-0.3-0.2-0.2-0.4-0.2-0.2-0.3-0.30.0-0.20.1-0.1-0.1-0.1-0.20.4-0.4
Vertical activity count, locomotor time 20.20.31.5-1.2-0.4-0.60.50.4-0.5-0.4-0.4-0.5-0.3-0.5-0.3-0.3-0.2-0.40.3-0.3-0.40.10.3-1.01.0
Light reinforcement 11.22.94.3-1.4-1.7-1.81.71.8-1.8-1.8-1.6-1.9-1.8-1.5-1.9-1.6-2.0-1.72.1-2.1-1.3-1.7-1.71.2-1.2
Light reinforcement 22.03.04.1-1.9-1.6-1.61.91.8-1.8-1.8-1.7-1.8-2.0-1.9-1.8-1.9-2.0-2.02.0-2.0-1.8-1.3-1.40.3-0.3
Bone: marrow area1.53.34.90.71.71.7-1.8-2.02.01.81.92.01.81.52.01.71.91.6-1.91.91.62.22.2-1.81.8
Bone: maximum diameter0.10.20.40.10.40.4-0.6-0.50.50.50.60.40.60.60.40.40.10.6-0.10.10.60.40.4-0.20.2
Bone: maximum force0.61.02.8-0.50.80.8-0.9-1.01.00.91.11.01.00.71.00.80.60.9-0.60.60.81.31.4-1.71.7
Bone: maximum moment0.91.62.7-0.11.11.1-1.2-1.31.31.21.41.31.31.01.31.21.01.2-1.01.01.11.51.6-1.61.6
Mean time between licks in bursts0.20.42.9-0.80.10.2-0.0-0.30.30.10.10.40.1-0.20.40.20.3-0.0-0.40.4-0.10.80.9-1.71.7
Mean num. licks in bursts0.20.30.5-0.6-0.7-0.60.50.5-0.6-0.7-0.5-0.6-0.5-0.4-0.6-0.6-0.6-0.40.6-0.6-0.4-0.6-0.60.4-0.4
Cd content in liver1.21.42.3-0.6-1.1-1.11.11.3-1.3-1.1-1.1-1.4-1.2-0.9-1.5-0.9-1.5-1.01.3-1.3-0.9-1.5-1.40.9-0.9
Co content in liver1.61.83.0-0.1-1.2-1.21.41.5-1.5-1.2-1.5-1.4-1.4-1.1-1.5-1.2-1.2-1.31.2-1.2-1.2-1.6-1.71.6-1.6
Cu content in liver1.11.34.02.01.11.1-1.2-1.01.01.11.01.01.21.40.91.21.11.3-1.01.01.20.40.31.3-1.3
Fe content in liver1.01.21.50.81.21.2-1.2-1.21.21.21.21.21.21.11.21.01.21.2-1.21.21.11.11.2-0.60.6
K content in liver0.10.10.80.80.20.1-0.1-0.00.00.2-0.10.10.10.20.20.00.40.1-0.30.30.0-0.1-0.20.9-0.9
Mg content in liver0.20.20.70.80.50.5-0.3-0.30.30.50.20.40.30.30.50.40.60.3-0.60.60.20.30.10.4-0.4
Mn content in liver0.10.20.3-0.2-0.5-0.50.50.5-0.5-0.5-0.6-0.4-0.4-0.5-0.2-0.3-0.1-0.40.1-0.1-0.6-0.3-0.40.2-0.2
Na content in liver0.40.41.01.00.50.5-0.7-0.60.60.50.60.60.70.80.50.50.80.7-0.60.60.60.40.10.8-0.8
Rb content in liver0.10.10.40.2-0.1-0.10.40.4-0.4-0.1-0.5-0.3-0.3-0.2-0.3-0.3-0.4-0.30.4-0.4-0.3-0.4-0.50.6-0.6
Se content in liver0.20.30.70.0-0.5-0.50.50.5-0.5-0.5-0.5-0.5-0.5-0.4-0.4-0.3-0.2-0.40.5-0.5-0.4-0.5-0.60.8-0.8
Sr content in liver0.20.20.6-0.20.10.10.0-0.20.20.10.00.30.1-0.10.50.20.7-0.0-0.60.6-0.20.50.5-0.80.8
Zn content in liver0.91.03.71.90.90.9-1.0-0.90.90.90.90.80.91.10.81.11.01.0-1.01.01.00.30.11.3-1.3
Bone: minimum diameter1.83.310.4-0.91.41.4-1.4-1.71.81.51.71.81.71.01.91.41.41.3-1.41.41.22.52.7-3.23.2
Time in familiar zone, hab. session 10.40.41.90.8-0.5-0.50.40.5-0.5-0.5-0.6-0.4-0.5-0.2-0.5-0.4-0.2-0.30.1-0.1-0.2-0.9-0.91.4-1.4
Time in novel zone, hab. session 10.10.10.3-0.30.50.5-0.4-0.40.40.50.50.20.40.30.20.4-0.00.30.0-0.00.30.50.4-0.40.4
Total zone transitions, hab. session 10.30.41.5-1.2-0.6-0.60.60.5-0.5-0.6-0.5-0.4-0.6-0.8-0.4-0.6-0.4-0.70.4-0.4-0.6-0.20.1-1.21.2
Total locomotion distance, hab. session 10.30.52.6-0.60.40.4-0.3-0.50.50.40.50.50.40.10.60.40.40.2-0.40.40.20.81.0-1.61.6
Locomotion velocity, hab. session 10.30.43.1-1.00.20.2-0.1-0.30.30.20.30.30.1-0.10.30.10.2-0.0-0.20.20.00.60.9-1.81.8
Time in familiar zone, hab. session 20.70.74.61.4-0.4-0.40.20.5-0.5-0.4-0.5-0.4-0.40.1-0.5-0.3-0.2-0.10.1-0.1-0.0-1.1-1.22.1-2.1
Time in novel zone, hab. session 20.70.72.6-0.80.70.7-0.6-0.80.80.70.80.70.70.40.80.60.40.5-0.40.40.41.21.2-1.61.6
Total zone transitions, hab. session 20.70.81.1-0.7-1.1-1.11.01.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-0.9-0.9-1.00.9-0.9-0.9-1.0-0.90.2-0.2
Total locomotion distance, hab. session 20.10.10.5-0.5-0.1-0.10.10.1-0.1-0.1-0.1-0.0-0.0-0.2-0.1-0.1-0.1-0.10.1-0.1-0.10.00.2-0.70.7
Locomotion velocity, hab. session 20.00.00.3-0.4-0.1-0.10.10.0-0.0-0.1-0.0-0.0-0.0-0.1-0.1-0.0-0.1-0.10.1-0.1-0.1-0.00.2-0.60.6
Novel to familiar place preference ratio0.20.20.5-0.20.40.4-0.3-0.40.40.40.40.40.30.20.50.40.40.2-0.30.30.20.70.6-0.50.5
Novelty place preference0.10.10.4-0.10.40.4-0.3-0.40.40.40.40.40.30.20.40.40.30.3-0.30.30.20.60.4-0.20.2
Time in novel zone, NPP test0.00.00.1-0.20.10.1-0.1-0.10.10.20.10.10.00.00.20.10.00.00.0-0.0-0.00.30.10.0-0.0
Total zone transitions, NPP test0.91.32.0-1.1-1.4-1.41.31.2-1.2-1.4-1.2-1.1-1.3-1.3-1.2-1.3-1.0-1.31.0-1.0-1.1-1.1-0.9-0.20.2
Total locomotion distance, NPP test0.10.21.2-0.8-0.2-0.20.1-0.00.0-0.10.00.0-0.1-0.20.0-0.1-0.1-0.20.1-0.1-0.10.20.4-1.11.1
Locomotion velocity, NPP test0.20.31.5-0.50.20.2-0.3-0.40.40.30.40.40.30.10.40.30.20.2-0.30.30.30.50.7-1.21.2
Intraocular pressure0.50.72.7-1.6-0.7-0.70.90.7-0.7-0.7-0.7-0.6-0.8-1.0-0.6-0.9-0.6-0.80.6-0.6-0.7-0.30.1-1.51.5
Delta distance traveled before/after self-admin2.93.04.21.82.02.0-2.0-1.71.62.02.01.42.01.91.71.81.91.9-1.81.81.71.71.40.1-0.1
Delta ambulatory time before/after self-admin2.53.14.21.92.02.0-2.0-1.81.72.02.01.52.12.01.81.81.92.0-1.81.81.71.71.40.2-0.2
Parametrial fat weight0.00.10.7-0.3-0.00.00.0-0.10.10.1-0.00.20.1-0.10.1-0.10.20.0-0.30.30.10.20.4-0.80.8
Pavlov. Cond. lever latency0.10.10.90.80.20.2-0.2-0.10.10.20.10.10.10.30.00.20.20.2-0.20.20.2-0.2-0.31.0-1.0
Pavlov. Cond. magazine entry latency0.10.10.7-0.6-0.1-0.10.0-0.00.1-0.10.00.1-0.0-0.20.1-0.1-0.0-0.10.0-0.0-0.00.30.4-0.90.9
Pavlov. Cond. change in total contacts0.70.82.9-1.7-0.8-0.80.80.7-0.7-0.8-0.7-0.6-0.7-1.0-0.5-0.8-0.8-0.80.8-0.8-0.9-0.10.1-1.51.5
Pavlov. Cond. index score0.30.31.1-1.0-0.6-0.60.60.5-0.5-0.6-0.5-0.5-0.5-0.7-0.5-0.6-0.6-0.60.6-0.6-0.5-0.2-0.1-0.70.7
Pavlov. Cond. latency score0.30.31.0-1.0-0.6-0.60.60.5-0.5-0.6-0.5-0.5-0.6-0.7-0.5-0.6-0.6-0.60.6-0.6-0.5-0.3-0.2-0.60.6
Pavlov. Cond. lever contacts0.20.32.0-0.90.10.1-0.0-0.20.20.00.20.20.1-0.10.30.00.1-0.0-0.00.0-0.00.50.7-1.41.4
Pavlov. Cond. magazine entry number0.40.51.21.10.80.7-0.7-0.70.70.80.70.70.70.80.60.80.80.7-0.80.80.70.40.30.5-0.5
Pavlov. Cond. intertrial magazine entries0.60.81.10.80.90.8-1.0-1.01.00.91.00.90.91.00.90.90.90.9-0.90.91.00.70.7-0.30.3
Pavlov. Cond. lever-magazine prob. diff.0.20.31.0-1.0-0.5-0.50.50.4-0.4-0.5-0.4-0.4-0.4-0.6-0.4-0.5-0.5-0.50.5-0.5-0.4-0.2-0.0-0.70.7
Pavlov. Cond. response bias0.20.21.5-1.0-0.2-0.20.20.1-0.1-0.3-0.1-0.1-0.1-0.4-0.0-0.2-0.2-0.30.2-0.2-0.20.20.4-1.21.2
Pavlov. Cond. lever latency1.11.52.0-1.3-1.4-1.41.41.4-1.4-1.3-1.4-1.3-1.3-1.3-1.3-1.3-1.2-1.21.3-1.3-1.3-1.1-1.0-0.00.0
Pavlov. Cond. magazine entry latency0.00.00.1-0.00.20.2-0.2-0.20.20.20.20.20.10.10.10.10.10.2-0.20.20.20.20.2-0.10.1
Pavlov. Cond. change in total contacts1.42.33.60.21.51.5-1.4-1.61.61.41.51.61.51.21.61.41.41.3-1.51.51.11.91.9-1.91.9
Pavlov. Cond. index score0.91.21.70.41.21.2-1.1-1.21.21.11.11.21.10.91.21.01.01.0-1.11.11.01.31.3-1.01.0
Pavlov. Cond. latency score0.91.21.50.61.21.2-1.1-1.21.21.11.21.21.11.01.21.11.11.0-1.21.21.01.21.2-0.70.7
Pavlov. Cond. lever contacts0.91.21.51.11.21.2-1.2-1.21.21.11.21.21.11.11.21.11.11.0-1.21.21.11.01.0-0.20.2
Pavlov. Cond. magazine entry number0.10.10.30.1-0.3-0.30.30.3-0.4-0.3-0.3-0.4-0.3-0.2-0.3-0.2-0.2-0.20.3-0.3-0.3-0.4-0.50.5-0.5
Pavlov. Cond. intertrial magazine entries0.10.11.0-0.50.10.10.1-0.00.00.1-0.10.10.0-0.20.20.10.2-0.1-0.10.1-0.20.40.4-1.01.0
Pavlov. Cond. lever-magazine prob. diff.0.81.11.50.51.11.1-1.1-1.21.21.01.11.21.10.91.11.01.00.9-1.11.10.91.21.2-0.90.9
Pavlov. Cond. response bias0.91.31.70.61.21.2-1.2-1.31.31.21.21.31.21.01.21.11.01.0-1.11.11.01.31.3-0.80.8
Time in closed arm before self-admin0.20.30.91.00.80.8-0.4-0.20.20.50.30.10.50.50.40.80.30.5-0.30.30.30.4-0.10.7-0.7
Time in closed arm after self-admin0.80.93.20.6-0.3-0.30.81.1-1.1-0.4-1.0-1.2-0.9-0.6-1.0-0.4-0.5-0.60.5-0.5-0.5-1.2-1.21.8-1.8
Time in open arm before self-admin0.40.41.0-0.10.40.4-0.7-0.90.90.60.80.80.50.60.70.20.70.4-0.60.60.70.71.0-0.70.7
Time in open arm after self-admin0.20.20.9-0.8-0.4-0.40.1-0.30.4-0.30.10.6-0.1-0.30.2-0.4-0.1-0.30.3-0.3-0.40.50.2-0.90.9
Bone: periosteal estimation1.53.16.0-0.21.61.6-1.7-1.91.91.61.91.81.81.41.91.61.41.6-1.41.41.52.22.4-2.42.4
Bone: periosteal perimeter0.50.91.40.30.80.8-1.1-1.11.10.91.21.01.11.01.00.90.81.0-0.80.81.11.11.1-0.70.7
Bone: post-yield work2.43.54.92.22.02.0-2.2-2.02.01.92.11.92.12.21.82.01.82.1-1.81.82.11.41.20.6-0.6
Progressive ratio test 1 active lever presses0.91.22.21.51.51.5-1.2-1.11.11.11.21.01.21.30.91.20.81.2-0.70.71.00.60.40.8-0.8
Progressive ratio test 1 breakpoint1.11.32.61.51.61.6-1.4-1.21.21.21.31.11.31.41.01.30.81.3-0.80.81.20.70.50.7-0.7
Progressive ratio test 1 inactive lever presses0.00.00.10.10.40.3-0.0-0.10.10.20.00.30.20.00.20.00.20.1-0.20.20.00.20.20.0-0.0
Progressive ratio test 2 active lever presses5.66.69.22.63.03.0-2.7-2.82.83.02.72.92.62.72.72.62.62.6-2.72.72.62.12.2-0.50.5
Progressive ratio test 2 breakpoint5.56.38.82.63.03.0-2.7-2.72.82.92.62.82.62.62.62.52.62.6-2.62.62.52.02.2-0.50.5
Progressive ratio test 2 inactive lever presses0.81.32.01.31.41.4-1.2-1.31.31.31.21.31.31.21.21.21.01.2-1.11.11.01.10.80.1-0.1
Incentive Sensitization - Responses4.76.79.11.92.92.9-2.6-2.72.73.02.72.82.52.52.72.52.82.5-2.82.82.52.42.7-1.61.6
Incentive Sensitization - Breakpoint4.96.48.92.02.82.8-2.6-2.72.73.02.62.72.52.52.72.42.72.5-2.82.82.52.32.6-1.41.4
Sum of active levers in priming session hrs 5-61.81.62.21.01.31.3-1.3-1.31.31.51.31.41.41.21.31.41.31.2-1.31.31.01.31.4-1.11.1
Progressive ratio0.40.63.70.9-0.3-0.2-0.10.2-0.3-0.40.1-0.5-0.40.3-0.6-0.3-0.3-0.10.4-0.40.5-1.2-1.11.9-1.9
Food seeking constrained by brief footshock0.80.93.8-2.0-0.5-0.61.00.7-0.6-0.6-0.8-0.5-0.8-1.2-0.4-0.5-0.6-0.90.5-0.5-1.00.20.4-2.02.0
Seeking ratio, punishment vs. effort0.71.06.1-1.8-0.2-0.40.80.4-0.4-0.1-0.8-0.0-0.4-1.20.2-0.3-0.1-0.60.0-0.0-1.20.90.9-2.52.5
Retroperitoneal fat weight0.10.51.0-1.0-0.7-0.81.00.8-0.8-0.4-1.0-0.6-0.8-1.0-0.6-0.8-0.4-0.80.4-0.4-0.7-0.6-0.3-0.50.5
Reaction time number correct1.01.93.30.71.61.6-1.3-1.41.41.51.41.51.31.21.51.81.41.3-1.41.41.31.61.6-1.01.0
Reaction time mean minus median1.74.26.8-1.8-2.2-2.22.02.2-2.2-2.4-2.0-2.3-1.9-1.8-2.4-2.1-2.6-1.82.5-2.5-1.7-2.1-2.00.3-0.3
Reaction time mean minus median AUC1.53.96.7-2.1-2.1-2.11.92.0-2.1-2.3-1.8-2.2-1.9-1.8-2.2-1.9-2.6-1.72.5-2.5-1.7-1.8-1.7-0.20.2
Reaction time num false alarms3.04.25.11.22.12.0-2.1-2.22.21.92.22.22.21.92.22.32.12.1-2.12.11.92.22.2-1.51.5
Reaction time num false alarms AUC2.64.15.11.32.12.0-2.1-2.22.21.92.22.22.22.02.22.32.02.1-2.02.01.92.12.1-1.41.4
Reaction time trials correct on left1.01.93.30.71.61.6-1.3-1.41.41.51.41.51.31.21.51.81.41.3-1.41.41.31.61.6-1.01.0
Reaction time trials on left1.01.83.00.61.51.5-1.3-1.41.41.41.31.41.21.11.51.71.41.2-1.31.31.21.51.6-1.11.1
Reaction time mean0.91.52.9-1.5-1.1-1.21.21.2-1.2-1.3-1.1-1.2-1.2-1.2-1.3-1.2-1.7-1.21.6-1.6-1.1-0.9-0.8-0.70.7
Reaction time mean AUC0.81.32.8-1.6-1.1-1.11.11.1-1.1-1.2-1.0-1.1-1.1-1.1-1.2-1.1-1.7-1.11.6-1.6-1.0-0.7-0.6-0.80.8
Median of all reaction times0.40.61.5-1.2-0.5-0.60.70.6-0.6-0.6-0.6-0.6-0.7-0.8-0.6-0.6-1.0-0.81.0-1.0-0.7-0.2-0.1-1.11.1
Reaction time omissions3.24.68.2-2.9-2.2-2.32.22.1-2.2-2.4-2.0-2.3-2.2-2.2-2.2-2.5-2.6-2.12.6-2.6-2.0-1.6-1.5-0.40.4
Reaction time false alarm rate0.30.40.60.60.60.6-0.7-0.70.70.50.70.70.80.70.60.60.70.7-0.70.70.60.60.5-0.20.2
Reaction time premature initiation rate0.30.52.41.50.30.4-0.6-0.40.40.40.50.30.40.80.10.70.50.5-0.60.60.8-0.4-0.41.2-1.2
Reaction time premature initiations0.61.02.71.70.91.0-1.1-1.01.01.01.10.90.91.30.81.41.11.1-1.11.11.30.30.40.7-0.7
Std. dev. reaction times1.42.64.9-1.5-1.6-1.61.61.7-1.7-1.8-1.5-1.8-1.5-1.4-1.9-1.6-2.2-1.42.1-2.1-1.4-1.6-1.50.2-0.2
Reaction time trials completed1.01.83.00.61.51.5-1.3-1.41.41.41.31.41.21.11.51.71.41.2-1.31.31.21.51.6-1.11.1
Reaction time trials AUC0.91.72.90.51.41.5-1.2-1.31.31.41.21.41.21.01.41.71.31.2-1.21.21.21.51.6-1.21.2
Run reversals in cocaine runway, females0.20.20.4-0.6-0.5-0.30.60.5-0.5-0.3-0.6-0.4-0.5-0.6-0.4-0.3-0.6-0.50.6-0.6-0.5-0.3-0.3-0.50.5
Run reversals in cocaine runway, males0.70.72.7-1.7-0.9-0.90.80.6-0.6-0.9-0.6-0.6-0.7-0.9-0.6-0.5-0.9-0.70.9-0.9-0.7-0.2-0.1-1.21.2
Latency to leave start box in cocaine runway0.50.61.11.00.80.9-0.9-0.80.80.70.90.71.10.90.70.60.81.0-0.80.80.80.50.4-0.10.1
Latency to leave start box in cocaine runway, F2.12.44.02.01.51.6-1.8-1.71.71.51.71.61.81.81.51.21.61.9-1.61.61.61.00.90.2-0.2
Latency to leave start box in cocaine runway, M1.71.62.7-1.6-1.2-1.21.41.4-1.4-1.4-1.3-1.4-1.2-1.4-1.3-1.3-1.4-1.31.4-1.4-1.3-0.9-0.8-0.70.7
Std. dev. time between licks in bursts0.20.30.70.10.50.5-0.4-0.50.50.50.40.60.40.30.60.60.60.3-0.60.60.30.70.8-0.90.9
Total sessions with >9 infusions0.70.82.61.61.00.9-1.0-0.90.90.80.90.90.91.10.70.90.50.8-0.50.50.80.30.11.2-1.2
Short access day 1 total inactive lever presses0.30.42.91.30.2-0.0-0.10.2-0.2-0.0-0.1-0.2-0.10.2-0.40.0-0.2-0.00.2-0.20.2-0.8-0.91.7-1.7
Short access day 10 total inactive lever presses0.71.82.9-0.2-1.6-1.71.51.6-1.6-1.4-1.6-1.5-1.6-1.4-1.5-1.5-0.8-1.40.8-0.8-1.1-1.6-1.40.9-0.9
Short access day 1 total infusions0.50.73.41.80.70.6-0.8-0.70.70.80.70.60.61.00.40.70.60.7-0.60.60.9-0.2-0.11.4-1.4
Short access day 10 total infusions1.82.33.61.81.61.7-1.8-1.81.81.41.71.91.71.71.61.61.31.6-1.21.21.61.20.80.6-0.6
Short access total infusions1.01.22.51.61.21.2-1.3-1.31.31.11.31.21.21.41.01.20.81.2-0.80.81.30.60.40.8-0.8
Short access day 1 locomotion0.10.11.00.50.10.2-0.1-0.00.0-0.10.00.00.10.2-0.10.2-0.3-0.00.2-0.20.1-0.3-0.41.0-1.0
Short access day 10 total locomotion0.30.51.0-0.6-0.9-0.70.70.6-0.5-1.0-0.7-0.4-0.5-0.7-0.6-0.6-1.0-0.61.0-1.0-0.7-0.5-0.70.3-0.3
Short access total locomotion0.20.30.50.70.60.6-0.7-0.60.60.30.70.60.70.70.50.70.20.6-0.20.20.60.40.20.5-0.5
One hour access (0.3 mA shock)6.27.210.92.73.23.3-2.9-2.82.83.12.82.72.82.82.72.82.92.8-2.82.82.72.32.3-0.40.4
Compulsive drug intake1.01.22.3-0.9-1.2-1.11.41.4-1.4-1.0-1.5-1.2-1.3-1.4-1.1-1.1-0.5-1.30.7-0.7-1.5-0.8-0.80.2-0.2
One hour access (shock baseline)8.012.218.03.34.24.2-3.9-3.83.73.93.83.63.93.83.63.93.33.7-3.33.33.63.12.9-0.70.7
Social response proportion0.50.61.0-0.6-0.8-0.80.70.8-0.8-1.0-0.7-0.9-0.7-0.6-0.8-0.9-0.8-0.60.9-0.9-0.7-0.7-0.80.3-0.3
Social responses1.21.52.3-1.0-1.2-1.21.31.4-1.4-1.3-1.3-1.4-1.2-1.0-1.3-1.4-1.5-1.01.5-1.5-1.2-1.2-1.30.5-0.5
Social time0.10.20.4-0.20.60.5-0.5-0.40.40.30.50.20.60.60.40.60.00.50.1-0.10.40.50.3-0.40.4
Soleus weight0.41.23.4-1.8-1.1-1.11.21.1-1.1-1.0-1.0-1.1-1.1-1.3-1.0-0.9-1.3-1.11.3-1.3-1.1-0.5-0.5-0.80.8
Bone: stiffness0.10.20.7-0.60.20.2-0.4-0.40.40.10.50.30.50.30.30.2-0.10.40.1-0.10.30.50.5-0.80.8
Tibialis anterior weight3.712.633.3-5.8-3.7-3.74.03.5-3.4-3.6-3.6-3.2-3.7-4.3-2.9-3.8-3.3-3.83.2-3.2-3.9-1.6-1.2-3.13.1
Time to tail flick, vehicle, before self-admin0.80.81.80.81.31.3-0.7-0.60.61.30.60.60.70.70.81.01.10.7-1.11.10.60.81.0-0.90.9
Time to tail flick, vehicle, after self-admin1.62.24.32.11.81.8-1.3-1.51.51.81.21.71.11.31.61.41.71.2-1.81.81.21.21.10.4-0.4
Time to tail flick, test, before self-admin0.50.51.0-0.2-0.7-0.70.60.6-0.6-0.6-0.6-0.6-0.7-0.5-0.7-0.4-0.6-0.60.8-0.8-0.5-0.8-0.91.0-1.0
Time to tail flick, test, after self-admin0.60.61.11.00.80.8-0.9-0.80.80.70.90.80.81.00.60.60.50.9-0.40.40.90.40.21.0-1.0
Delta time to tail flick, vehicle, before/after SA1.81.73.31.81.21.2-1.4-1.41.51.11.31.61.21.41.31.41.21.3-1.41.41.50.90.70.9-0.9
Delta time to tail flick, test, before/after SA0.00.00.10.1-0.0-0.00.0-0.00.0-0.3-0.10.10.0-0.0-0.0-0.2-0.30.00.2-0.20.0-0.1-0.20.3-0.3
Tibia length0.41.13.21.81.01.0-1.0-0.91.01.20.81.01.01.01.00.91.21.0-1.21.21.00.60.41.1-1.1
Ambulatory time before self-admin0.71.02.0-1.1-1.3-1.31.10.9-0.8-1.4-1.1-0.6-1.2-1.1-0.9-1.2-1.0-1.11.0-1.0-0.9-0.9-0.7-0.20.2
Ambulatory time after self-admin0.50.61.00.60.70.7-1.0-0.90.80.61.00.71.00.90.80.60.80.9-0.70.70.90.90.7-0.10.1
Bone: tissue strength1.51.53.01.71.01.0-1.5-1.31.31.11.41.11.41.51.01.11.21.5-1.21.21.50.50.51.0-1.0
Total heroin consumption1.01.22.30.11.01.0-0.9-1.21.31.01.01.41.20.81.21.11.10.9-0.90.90.61.31.2-1.51.5
Bone: trabecular number0.61.01.51.01.21.2-1.2-1.11.11.11.11.11.11.11.01.20.91.1-0.90.91.00.90.9-0.30.3
Bone: trabecular spacing1.82.33.0-1.2-1.7-1.71.71.7-1.7-1.6-1.7-1.6-1.6-1.6-1.6-1.7-1.5-1.51.5-1.5-1.5-1.5-1.40.7-0.7
Bone: trabecular thickness3.64.45.61.52.42.4-2.3-2.32.32.32.32.22.32.22.22.31.92.2-2.02.02.12.12.1-1.31.3
Bone: trabecular tissue density2.63.95.9-2.2-2.0-2.02.02.1-2.1-2.1-1.9-2.2-1.9-1.9-2.2-2.1-2.4-1.82.4-2.4-1.8-1.9-1.70.2-0.2
Water consumed over 24 hours0.00.10.1-0.3-0.3-0.20.20.2-0.2-0.3-0.1-0.2-0.1-0.2-0.2-0.2-0.4-0.20.3-0.3-0.2-0.1-0.1-0.20.2
Number of responses in last shaping day0.30.40.70.80.60.6-0.8-0.60.60.50.80.50.80.80.40.70.30.7-0.30.30.80.20.20.5-0.5