Hub : Genes

Slc35a1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Slc35a1 0.09 0.06 2.8e-06 0.06 0.06 0.06 0.06 1.3e-06 4.4e-06 2.4e-06 5.6e-06
2 NAcc intron excision ratio chr5_54022929_54026987 0.04 0.03 3.3e-05 0.03 0.03 0.03 0.03 6.8e-06 2.7e-05 2.6e-05 1.3e-05
3 NAcc mRNA stability Slc35a1 0.03 0.02 4.1e-04 0.03 0.02 0.02 0.03 1.0e-04 1.3e-04 3.1e-04 9.1e-05
4 Liver gene expression Slc35a1 0.12 0.08 1.6e-12 0.08 0.09 0.07 0.09 4.8e-09 7.8e-10 4.3e-08 1.0e-09
5 Adipose gene expression Slc35a1 0.1 0.07 9.6e-10 0.06 0.06 0.06 0.06 5.8e-07 2.3e-07 6.3e-07 2.5e-07
6 NAcc intron excision ratio chr5_54027718_54029841 0.03 0.03 1.8e-05 0.04 0.03 0.04 0.04 2.8e-06 5.7e-06 2.4e-06 2.6e-06
7 NAcc intron excision ratio chr5_54027121_54027542 0.03 0.02 3.1e-04 0.02 0.02 0.01 0.02 1.7e-03 2.8e-04 6.5e-03 7.2e-04
8 BLA mRNA stability Slc35a1 0.08 0.06 7.5e-04 0.03 0.05 0.03 0.03 7.8e-03 1.7e-03 1.4e-02 1.0e-02
9 Adipose mRNA stability Slc35a1 0.05 0.03 2.4e-05 0.03 0.03 0.03 0.03 1.4e-04 2.2e-04 1.5e-04 1.6e-04
10 Brain intron excision ratio chr5_54022929_54026987 0.04 0.03 2.6e-03 0.03 0.01 0.02 0.02 3.7e-04 2.4e-02 9.9e-03 3.7e-03
11 PL intron excision ratio chr5_54027718_54029841 0.02 0.02 7.4e-03 0 0.01 0.02 0.01 2.4e-01 3.4e-02 4.6e-03 2.4e-02
12 IC intron excision ratio chr5_54022929_54026987 0.14 0.1 1.8e-05 0.02 0.1 0.07 0.05 5.6e-02 6.7e-05 5.2e-04 4.2e-03
13 PL mRNA stability Slc35a1 0.04 0.03 1.8e-04 0.02 0.03 0.02 0.02 3.4e-03 4.7e-04 3.8e-03 2.1e-03
14 IC intron excision ratio chr5_54027121_54027542 0.07 0.06 4.8e-03 -0 0.01 0.03 0.01 3.5e-01 7.9e-02 2.6e-02 1.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.61.11.81.0-1.01.01.01.00.90.91.21.2-1.21.3-1.30.51.0
Area under the delay curve0.10.10.3-0.60.2-0.2-0.2-0.2-0.2-0.2-0.4-0.20.1-0.50.4-0.10.1
BMI with tail3.311.417.03.8-3.83.83.83.93.73.92.93.6-3.71.3-1.74.11.2
BMI without tail2.98.811.93.4-3.23.23.23.23.23.23.22.8-2.92.3-2.62.62.4
Body weight6.126.532.65.7-5.65.65.65.65.65.65.05.2-5.44.0-3.95.13.7
Weight adjusted by age1.21.92.41.5-1.41.41.31.31.51.31.51.4-1.41.5-1.40.91.3
Bone surface1.83.36.11.8-1.71.71.61.61.71.52.21.8-1.72.4-2.50.62.2
Bone volume0.91.73.71.2-1.11.11.11.01.11.01.71.3-1.21.6-1.90.21.7
Breakpoint value in progressive ratio session0.30.30.90.2-0.60.60.40.40.50.30.80.5-0.50.9-0.9-0.00.5
Number of licking bursts0.10.10.2-0.20.4-0.4-0.4-0.4-0.3-0.4-0.2-0.30.4-0.20.0-0.5-0.1
Context. condit. distance diff. score0.81.01.5-0.91.0-1.0-0.9-0.9-0.9-0.9-1.1-1.21.1-0.51.2-0.5-1.0
Locomotion velocity, session 10.20.20.7-0.30.4-0.4-0.3-0.3-0.4-0.3-0.5-0.30.2-0.80.60.0-0.8
Locomotion distance, session 13.64.65.7-2.42.4-2.4-2.3-2.3-2.3-2.2-2.3-2.12.1-1.71.9-1.9-1.6
Locomotion velocity, session 20.10.10.6-0.00.1-0.10.00.0-0.10.1-0.40.2-0.1-0.50.70.5-0.8
Locomotion distance, session 25.17.19.7-2.72.7-2.7-2.6-2.6-2.7-2.5-3.1-2.62.6-2.83.1-1.6-2.6
Locomotion velocity, session 32.32.74.7-1.51.6-1.6-1.5-1.5-1.6-1.4-2.0-1.61.5-1.82.2-0.6-2.0
Locomotion distance, session 33.43.77.3-1.71.8-1.8-1.7-1.7-1.8-1.6-2.4-1.91.9-2.22.7-0.6-2.3
Stereotopy head waving bouts, day 30.91.02.40.9-1.01.00.80.81.00.81.20.9-1.01.2-1.30.31.6
Stereotopy head waving duration, day 31.61.92.51.5-1.51.51.51.51.51.51.41.6-1.60.9-1.21.31.1
Locomotion velocity, session 70.70.82.7-0.70.7-0.7-0.6-0.5-0.7-0.5-1.3-0.60.8-0.91.60.3-1.6
Locomotion distance, session 72.02.54.9-1.51.5-1.5-1.4-1.4-1.5-1.3-2.0-1.61.7-1.42.2-0.5-2.1
Stereotopy head waving bouts, day 70.50.61.80.8-0.80.80.80.80.70.90.10.4-0.6-0.70.51.4-0.5
Stereotopy head waving duration, day 71.92.34.51.7-1.71.71.81.81.71.81.11.5-1.70.1-0.42.10.2
Locomotion velocity, session 85.16.111.3-2.22.4-2.4-2.1-2.1-2.2-1.9-3.0-2.32.3-3.23.4-0.7-3.0
Locomotion distance, session 86.59.512.6-3.13.2-3.2-3.1-3.1-3.1-3.0-3.6-3.33.1-2.53.5-2.0-3.1
Degree of sensitization distance0.30.40.60.6-0.70.70.70.70.60.70.50.7-0.60.5-0.30.8-0.0
Degree of sensitization stereotypy0.91.03.30.8-0.80.80.90.90.71.0-0.20.5-0.6-1.31.01.8-1.2
Conditioned locomotion0.30.31.20.3-0.40.40.40.40.50.30.60.4-0.40.9-0.8-0.01.1
Cocaine response after cond. corrected0.70.81.00.9-1.01.01.00.91.00.91.00.7-0.70.9-0.80.70.9
Cocaine response after cond. not corrected0.30.30.50.6-0.60.60.60.60.60.60.70.4-0.30.7-0.60.40.7
Cocaine response before conditioning0.10.10.2-0.20.2-0.2-0.2-0.2-0.3-0.2-0.3-0.00.1-0.40.3-0.0-0.5
Saline control response0.81.12.40.9-1.01.00.90.90.90.91.31.0-0.81.6-1.40.41.3
Bone: connectivity density1.01.62.71.2-1.21.21.31.31.21.21.41.5-1.51.6-1.40.81.0
Bone: cortical apparent density0.10.10.70.10.3-0.3-0.3-0.3-0.1-0.30.1-0.30.3-0.2-0.4-0.60.8
Bone: cortical area4.26.48.72.9-2.62.62.62.62.72.62.62.6-2.51.9-2.22.12.4
Bone: cortical porosity0.40.52.5-0.0-0.10.1-0.1-0.10.1-0.20.60.1-0.11.3-1.1-0.81.6
Bone: cortical porosity0.80.92.90.7-0.70.70.60.60.70.61.10.8-0.81.4-1.30.11.7
Bone: cortical thickness1.01.62.91.7-1.31.31.31.31.41.31.31.2-1.10.6-1.11.11.4
Bone: cortical thickness0.30.41.20.6-0.50.50.60.70.50.70.10.5-0.5-0.40.41.1-0.7
Bone: cortical tissue density0.10.10.60.00.4-0.4-0.3-0.3-0.1-0.40.1-0.40.3-0.2-0.3-0.60.8
Condit. Reinf. active minus inactive responses2.62.93.8-1.81.8-1.8-1.7-1.7-1.8-1.6-1.9-1.51.7-1.71.9-1.1-1.9
Condit. Reinf. active-inactive response ratio0.60.71.0-0.80.8-0.8-0.9-0.9-0.9-0.8-0.9-0.70.9-0.70.8-0.7-1.0
Condit. Reinf. active responses1.72.13.2-1.41.5-1.5-1.4-1.4-1.4-1.3-1.8-1.21.3-1.51.8-0.7-1.7
Condit. Reinf. inactive responses0.80.91.8-1.01.0-1.0-0.9-0.9-1.0-0.8-1.2-0.80.7-1.21.3-0.4-1.0
Incentive salience index mean0.91.11.8-1.11.0-1.0-1.0-1.0-1.0-0.9-1.3-0.81.0-1.11.3-0.5-1.3
Condit. Reinf. lever presses0.10.10.3-0.1-0.10.10.00.00.10.1-0.30.00.0-0.20.60.4-0.6
Condit. Reinf. active minus inactive responses0.50.71.40.9-0.80.80.90.90.81.00.50.9-1.10.4-0.11.20.3
Condit. Reinf. active-inactive response ratio0.40.51.60.3-0.20.20.40.40.30.5-0.50.3-0.3-0.81.11.3-1.2
Condit. Reinf. active responses0.91.32.81.1-1.01.01.11.11.01.01.11.2-1.31.2-1.10.71.7
Condit. Reinf. inactive responses1.01.26.10.7-0.70.70.60.60.70.51.20.7-0.91.6-1.6-0.22.5
Condit. Reinf. lever presses1.31.82.61.4-1.41.41.41.41.41.41.21.6-1.61.2-0.91.41.1
Condit. Reinf. lever reinforcers received1.21.73.01.3-1.21.21.21.31.21.21.31.4-1.61.4-1.30.91.7
Conditioned reinforcement - actives0.30.50.80.9-0.70.70.80.80.80.80.50.7-0.60.3-0.20.90.1
Conditioned reinforcement - inactives0.00.00.40.10.0-0.0-0.2-0.10.0-0.1-0.2-0.2-0.00.60.1-0.1-0.0
Conditioned locomotion1.01.31.71.3-1.21.21.31.31.21.31.11.3-1.01.2-0.81.20.2
Patch foraging indifference point 0 sec0.10.20.40.2-0.30.30.40.40.20.30.50.5-0.60.6-0.60.10.2
Patch foraging indifference point AUC1.72.43.71.9-1.71.71.71.71.71.71.51.6-1.21.4-1.21.51.0
Delay disc. indifference point, 0s delay0.40.41.0-0.50.5-0.5-0.5-0.5-0.5-0.5-0.9-0.70.6-0.91.0-0.1-0.7
Delay disc. indifference point, 16s delay0.10.10.30.0-0.20.20.30.30.30.30.30.3-0.40.1-0.30.20.5
Delay disc. indifference point, 2s delay0.20.21.00.2-0.40.40.30.30.40.30.40.2-0.20.5-0.40.11.0
Delay disc. indifference point, 24s delay0.00.00.1-0.1-0.30.30.10.10.20.10.0-0.10.10.20.00.1-0.0
Delay disc. indifference point, 4s delay0.40.40.9-0.90.7-0.7-0.6-0.6-0.7-0.6-0.7-0.50.7-0.60.7-0.4-0.3
Delay disc. indifference point, 8s delay0.00.00.3-0.3-0.00.0-0.1-0.1-0.1-0.1-0.10.1-0.2-0.2-0.0-0.10.5
Indifference point function ln k0.20.41.1-0.80.6-0.6-0.6-0.5-0.6-0.5-0.7-0.60.1-1.00.7-0.2-0.8
Indifference point function log k0.20.41.1-0.80.6-0.6-0.6-0.5-0.6-0.5-0.7-0.60.1-1.00.7-0.2-0.8
Patch foraging total patch changes 0 sec0.00.10.20.1-0.20.20.30.30.10.30.30.4-0.40.4-0.20.2-0.0
Patch foraging total patch changes 12 sec1.01.32.91.1-1.31.31.31.31.21.40.71.4-1.10.2-0.11.7-0.1
Patch foraging total patch changes 18 sec0.10.20.50.6-0.40.40.40.40.30.40.50.4-0.30.7-0.50.20.2
Patch foraging total patch changes 24 sec0.91.62.91.1-1.41.41.21.21.21.21.41.4-1.11.7-1.40.81.3
Patch foraging total patch changes 6 sec0.20.41.30.6-0.50.50.60.60.40.50.70.6-0.51.1-0.70.30.4
Patch foraging time to switch 0 sec1.22.53.4-1.81.7-1.7-1.7-1.7-1.8-1.7-1.5-1.61.5-0.81.1-1.6-1.2
Patch foraging water rate 0 sec1.02.12.51.6-1.61.61.61.61.51.61.41.5-1.41.2-1.11.41.2
Patch foraging water rate 12 sec0.30.61.40.9-0.70.70.80.80.70.80.50.7-0.61.2-0.30.90.6
Patch foraging water rate 18 sec0.30.52.10.8-0.70.70.60.60.60.7-0.30.3-0.3-0.91.01.4-0.5
Patch foraging water rate 24 sec0.30.52.80.20.1-0.10.10.2-0.00.2-0.80.1-0.1-1.71.31.0-0.6
Patch foraging water rate 6 sec0.50.71.81.1-0.90.91.01.00.91.10.50.8-0.70.20.01.30.2
Seeking ratio, delayed vs. immediate footshock0.10.20.7-0.1-0.20.20.10.10.10.00.30.7-0.40.9-0.6-0.30.3
Distance traveled before self-admin0.10.10.20.2-0.10.10.20.20.10.3-0.00.2-0.0-0.30.30.5-0.5
Distance traveled after self-admin0.10.10.4-0.30.1-0.1-0.3-0.2-0.0-0.2-0.5-0.30.2-0.10.60.10.1
Extensor digitorum longus weight4.417.221.34.6-4.44.44.44.44.54.44.04.4-4.23.6-3.23.93.0
Bone: elastic displacement0.20.20.7-0.40.4-0.4-0.5-0.5-0.4-0.5-0.0-0.40.30.3-0.3-0.90.5
Bone: elastic work1.62.13.21.4-1.41.41.31.31.31.21.71.4-1.61.5-1.80.71.7
Bone: endosteal estimation4.39.511.73.3-3.23.23.33.33.23.33.03.4-3.42.8-2.52.82.1
Bone: endosteal perimeter3.06.57.72.6-2.62.62.62.62.62.52.62.8-2.82.7-2.42.02.1
Epididymis fat weight0.00.10.8-0.1-0.30.30.0-0.00.2-0.00.4-0.10.10.3-0.7-0.40.9
Delta time in closed arm before/after self-admin0.00.00.2-0.2-0.00.0-0.2-0.20.0-0.20.1-0.10.4-0.3-0.2-0.3-0.0
Delta time in open arm before/after self-admin0.20.20.9-0.10.6-0.6-0.2-0.2-0.4-0.1-0.6-0.20.1-1.00.80.3-0.5
Diff in mean of infusions in LGA sessions1.21.52.4-1.51.3-1.3-1.3-1.4-1.4-1.4-0.9-1.21.1-0.60.5-1.5-1.0
Delay discount exponential model param0.10.10.50.7-0.30.30.30.30.30.30.50.2-0.20.6-0.50.1-0.0
Extinction: sum of active levers before priming1.01.12.5-1.20.8-0.8-1.0-0.9-0.9-0.9-1.2-0.80.8-1.41.3-0.5-1.6
Active lever presses in extinction session 61.01.01.7-1.31.1-1.1-1.1-1.1-1.1-1.1-0.8-1.01.2-0.30.5-1.2-0.5
Bone: final force2.54.04.92.1-2.12.12.12.12.12.12.22.2-2.11.7-1.91.61.6
Bone: final moment3.45.46.52.5-2.42.42.42.42.42.42.52.5-2.41.9-2.21.82.0
Food consumed during 24 hour testing period1.52.12.61.4-1.51.51.51.51.61.51.51.5-1.41.2-1.31.21.2
Glucose0.00.10.20.4-0.30.30.20.20.20.20.30.10.00.4-0.20.20.0
Heart weight2.23.44.02.0-2.02.02.02.02.02.01.91.6-1.71.9-1.61.61.6
Delay discount hyperbolic model param0.00.00.20.5-0.00.00.10.10.10.10.20.1-0.10.3-0.20.0-0.2
Intermittent access intake day 1-15 change0.91.82.6-1.61.3-1.3-1.4-1.4-1.3-1.4-1.5-1.21.5-1.11.3-1.1-1.1
Intermittent access intake escalation0.81.72.6-1.61.2-1.2-1.4-1.4-1.3-1.4-1.4-1.21.5-1.01.2-1.1-0.9
Intermittent access intake escalation 21.31.42.4-1.41.1-1.1-1.1-1.1-1.2-1.0-1.5-0.91.2-1.41.6-0.5-1.4
Intermitt. access day 1 inactive lever presses0.10.21.70.10.0-0.0-0.2-0.20.0-0.1-0.4-0.40.5-1.30.70.2-0.5
Intermitt. access day 15 inactive lever presses0.10.10.7-0.20.2-0.2-0.2-0.2-0.1-0.20.1-0.10.50.5-0.3-0.50.8
Intermitt. access escalation Index0.20.30.7-0.50.4-0.4-0.5-0.5-0.4-0.5-0.1-0.30.40.5-0.3-0.80.8
Intermittent access day 1 total infusions0.50.81.81.0-0.90.91.01.00.91.00.90.9-0.91.3-0.70.90.6
Intermittent access day 15 total infusions0.00.10.20.0-0.20.20.20.20.20.2-0.00.30.10.40.20.4-0.2
Intermittent access terminal intake (last 3 days)0.10.10.2-0.40.2-0.2-0.2-0.1-0.2-0.1-0.4-0.00.40.40.40.1-0.5
Intermittent access total infusions0.60.71.30.8-0.80.80.90.90.91.00.61.1-0.81.1-0.31.10.1
Intermittent access day 1 locomotion0.50.62.80.7-0.60.60.50.50.50.51.10.4-0.61.7-1.3-0.10.9
Intermittent access day 15 total locomotion0.30.52.40.6-0.40.40.40.40.40.40.80.5-0.51.5-0.9-0.01.0
Intermittent access total locomotion0.40.52.40.6-0.50.50.50.50.50.40.90.6-0.51.6-1.1-0.00.6
Intermittent access standard deviation0.20.31.3-0.40.3-0.3-0.3-0.3-0.4-0.2-0.9-0.10.7-0.41.10.3-1.2
Left kidney weight2.19.713.33.7-3.43.43.43.43.53.43.03.0-2.82.9-2.23.21.9
Right kidney weight1.88.310.43.2-3.03.03.13.13.13.12.92.7-2.53.0-2.42.62.4
Cocaine induced anxiety0.40.52.3-0.50.6-0.6-0.5-0.5-0.6-0.4-0.8-0.50.4-1.20.9-0.1-1.5
Post-drug Anxiety0.00.00.10.3-0.10.10.10.20.10.2-0.10.1-0.2-0.40.30.4-0.3
Baseline Anxiety0.10.11.20.2-0.20.20.10.10.20.10.30.2-0.00.5-0.4-0.11.1
Tail length1.66.413.62.4-2.22.22.12.02.31.93.11.9-1.93.7-3.50.63.7
Length with tail3.013.119.73.8-3.53.53.53.53.63.44.03.5-3.54.4-3.82.33.9
Length without tail1.44.76.02.3-2.42.42.42.42.32.41.92.3-2.31.5-1.22.41.4
Times rat made contact with spout0.20.21.2-0.0-0.20.20.10.10.20.00.5-0.00.01.1-0.7-0.40.9
Lifetime Intake0.60.81.30.9-0.90.90.91.00.91.00.61.0-0.81.0-0.21.20.1
Liver weight, left2.44.07.51.9-2.02.01.71.72.01.62.51.8-1.72.5-2.70.62.6
Liver weight, right1.22.13.21.4-1.51.51.41.31.51.31.71.2-1.21.8-1.70.71.8
Locomotor activity0.50.81.4-1.20.8-0.8-0.9-0.9-1.0-0.9-0.9-1.10.9-1.10.7-0.8-0.7
Locomotor testing distance0.20.30.6-0.60.6-0.6-0.6-0.6-0.7-0.6-0.4-0.70.4-0.70.3-0.6-0.1
Locomotor testing rearing0.61.21.7-1.11.0-1.0-1.1-1.1-1.1-1.1-1.2-1.31.0-1.31.1-0.9-0.7
Locomotion in novel chamber0.50.61.70.5-0.80.80.80.80.70.80.81.1-1.30.5-0.70.70.3
Locomotion in novel chamber post-restriction0.30.51.0-1.01.0-1.0-0.7-0.8-0.9-0.8-0.4-0.60.4-0.60.1-0.9-0.1
Fecal boli incidents, locomotor time 10.20.41.40.4-0.40.40.40.40.50.30.80.5-0.10.9-0.9-0.11.2
Change in fecal boli incidents, locomotor task0.10.10.6-0.40.4-0.4-0.4-0.4-0.4-0.5-0.1-0.1-0.30.2-0.3-0.80.1
Time >=10cm from walls, locomotor time 10.20.21.60.1-0.10.10.20.20.20.20.10.2-0.31.3-0.10.20.6
Bouts of movement, locomotor time 10.30.30.8-0.60.5-0.5-0.6-0.6-0.5-0.6-0.5-0.40.6-0.90.3-0.5-0.7
Total resting periods, locomotor time 10.10.10.4-0.30.2-0.2-0.3-0.3-0.2-0.30.0-0.20.4-0.2-0.3-0.60.0
Rest time, locomotor task time 10.10.20.6-0.40.2-0.2-0.4-0.5-0.3-0.5-0.0-0.30.60.2-0.2-0.7-0.1
Distance moved, locomotor task time 10.30.41.20.6-0.50.50.80.80.50.80.30.6-0.9-0.70.11.1-0.3
Vertical activity count, locomotor time 10.10.20.90.10.1-0.10.30.3-0.00.3-0.20.3-0.3-1.00.60.7-0.3
Time >=10cm from walls, locomotor time 21.31.93.81.3-1.41.41.31.31.31.21.31.1-1.41.9-1.30.91.9
Bouts of movement, locomotor time 20.00.00.1-0.10.2-0.2-0.2-0.2-0.2-0.2-0.1-0.20.0-0.00.0-0.20.0
Total resting periods, locomotor time 20.00.00.1-0.20.3-0.3-0.2-0.2-0.2-0.3-0.1-0.20.2-0.20.0-0.30.1
Rest time, locomotor task time 20.50.61.1-1.01.0-1.0-0.8-0.9-1.0-0.9-0.6-0.40.6-0.50.3-1.0-0.7
Distance moved, locomotor task time 20.40.41.60.1-0.30.30.40.40.30.5-0.50.1-0.4-1.31.11.1-1.0
Vertical activity count, locomotor time 20.50.72.40.9-0.60.60.91.00.71.00.20.8-0.9-0.60.51.5-0.2
Light reinforcement 11.23.06.42.2-1.91.92.02.01.92.11.11.9-1.70.4-0.32.5-0.2
Light reinforcement 21.52.34.22.0-1.51.51.81.81.61.81.21.7-1.40.8-0.62.00.2
Bone: marrow area4.49.611.83.3-3.23.23.33.33.23.33.13.4-3.42.8-2.52.82.1
Bone: maximum diameter4.58.49.83.1-2.92.92.92.93.02.83.13.0-3.02.9-2.92.03.0
Bone: maximum force3.86.88.12.8-2.82.82.82.82.82.82.62.8-2.81.8-2.12.52.1
Bone: maximum moment4.57.89.23.0-3.03.03.03.03.02.92.93.0-3.02.0-2.42.52.4
Mean time between licks in bursts0.20.50.90.9-0.70.70.80.80.70.80.60.9-0.90.2-0.40.80.0
Mean num. licks in bursts0.10.21.00.3-0.40.40.30.30.40.30.40.2-0.31.0-0.40.20.7
Cd content in liver2.83.24.22.1-2.02.01.91.91.91.91.81.9-1.81.1-1.51.61.3
Co content in liver0.10.10.30.2-0.20.20.20.20.30.20.40.3-0.20.5-0.6-0.10.6
Cu content in liver0.00.00.2-0.10.2-0.2-0.2-0.2-0.1-0.20.0-0.10.00.2-0.2-0.40.1
Fe content in liver0.40.52.3-0.10.2-0.2-0.3-0.3-0.1-0.40.6-0.20.21.1-1.2-1.21.5
K content in liver1.11.01.4-1.11.1-1.1-1.1-1.2-1.2-1.2-0.9-1.11.1-0.70.6-1.2-0.2
Mg content in liver0.10.10.3-0.30.4-0.4-0.4-0.4-0.4-0.4-0.2-0.30.4-0.10.0-0.50.2
Mn content in liver0.20.20.50.4-0.40.40.40.40.30.30.50.3-0.40.6-0.50.10.7
Na content in liver2.02.13.2-1.51.6-1.6-1.6-1.6-1.6-1.7-1.2-1.61.6-1.00.7-1.8-0.6
Rb content in liver0.80.91.2-0.91.0-1.0-1.0-1.0-1.1-1.1-0.8-1.01.1-0.90.5-1.1-0.2
Se content in liver1.92.23.5-1.61.6-1.6-1.7-1.7-1.6-1.7-1.2-1.71.8-0.50.7-1.9-0.5
Sr content in liver1.81.52.0-1.31.3-1.3-1.2-1.2-1.3-1.2-1.3-1.31.2-1.01.2-0.9-1.4
Zn content in liver0.10.10.30.4-0.40.40.40.40.40.40.20.4-0.40.20.00.5-0.2
Bone: minimum diameter1.93.44.42.1-2.02.02.02.02.02.01.72.0-2.01.3-1.31.81.5
Time in familiar zone, hab. session 11.21.21.51.2-1.21.21.21.21.21.11.20.8-1.00.9-1.00.91.2
Time in novel zone, hab. session 14.44.47.3-2.02.0-2.0-1.9-1.9-2.1-1.8-2.4-1.92.1-2.72.5-1.0-2.7
Total zone transitions, hab. session 18.712.217.0-3.83.9-3.9-3.9-3.9-3.7-4.0-2.9-4.03.9-1.61.8-4.1-1.4
Total locomotion distance, hab. session 15.68.015.5-3.23.1-3.1-3.3-3.3-3.0-3.4-2.0-3.13.2-0.40.8-3.9-0.4
Locomotion velocity, hab. session 14.15.913.4-2.72.6-2.6-2.8-2.9-2.5-3.0-1.5-2.62.70.30.2-3.70.2
Time in familiar zone, hab. session 20.10.10.3-0.10.1-0.10.00.0-0.00.1-0.3-0.0-0.1-0.30.60.4-0.3
Time in novel zone, hab. session 20.00.00.10.1-0.10.10.10.10.00.10.10.20.0-0.3-0.10.0-0.3
Total zone transitions, hab. session 24.55.77.2-2.62.7-2.7-2.5-2.5-2.5-2.5-2.4-2.52.5-1.82.1-2.1-2.0
Total locomotion distance, hab. session 21.31.73.6-1.51.5-1.5-1.5-1.6-1.4-1.6-0.9-1.21.30.40.3-1.9-0.2
Locomotion velocity, hab. session 21.11.43.5-1.31.3-1.3-1.4-1.4-1.2-1.5-0.7-1.11.20.7-0.0-1.90.0
Novel to familiar place preference ratio0.50.52.00.1-0.00.0-0.2-0.20.0-0.30.8-0.40.21.4-1.4-1.11.1
Novelty place preference0.60.62.2-0.30.4-0.4-0.5-0.6-0.4-0.60.5-0.70.51.2-1.2-1.50.9
Time in novel zone, NPP test0.60.62.4-0.40.5-0.5-0.6-0.7-0.5-0.80.4-0.90.71.1-1.1-1.60.7
Total zone transitions, NPP test3.24.65.4-2.22.3-2.3-2.1-2.1-2.2-2.0-2.3-2.32.3-2.12.2-1.5-2.2
Total locomotion distance, NPP test0.60.91.2-1.11.0-1.0-1.0-1.0-1.0-1.0-1.0-0.80.9-0.60.8-0.9-0.9
Locomotion velocity, NPP test0.30.50.7-0.80.7-0.7-0.8-0.8-0.7-0.8-0.7-0.50.7-0.30.5-0.7-0.7
Intraocular pressure1.92.85.01.4-1.71.71.71.71.61.61.92.0-2.21.0-1.81.21.3
Delta distance traveled before/after self-admin0.10.10.3-0.30.2-0.2-0.3-0.3-0.1-0.3-0.3-0.50.10.60.1-0.30.3
Delta ambulatory time before/after self-admin0.20.20.3-0.60.4-0.4-0.6-0.6-0.3-0.6-0.4-0.60.20.40.2-0.60.3
Parametrial fat weight0.71.74.2-1.11.4-1.4-1.0-1.0-1.3-0.9-1.6-1.21.0-1.21.8-0.2-2.0
Pavlov. Cond. lever latency0.30.41.2-0.60.6-0.6-0.6-0.6-0.7-0.6-0.7-0.50.5-1.10.7-0.3-0.6
Pavlov. Cond. magazine entry latency0.40.52.00.2-0.20.20.10.00.2-0.10.80.2-0.11.4-1.3-0.71.2
Pavlov. Cond. change in total contacts0.10.10.4-0.40.2-0.2-0.5-0.5-0.4-0.5-0.2-0.40.60.20.0-0.6-0.1
Pavlov. Cond. index score0.20.31.40.2-0.30.30.20.20.30.10.70.2-0.11.2-1.0-0.40.9
Pavlov. Cond. latency score0.40.51.80.5-0.50.50.40.40.50.30.90.5-0.41.3-1.2-0.21.0
Pavlov. Cond. lever contacts0.40.51.70.6-0.60.60.50.50.60.50.90.5-0.51.3-1.00.10.8
Pavlov. Cond. magazine entry number0.40.52.0-0.40.4-0.4-0.3-0.3-0.4-0.2-0.9-0.40.3-1.41.30.4-1.0
Pavlov. Cond. intertrial magazine entries1.82.23.8-1.41.4-1.4-1.4-1.4-1.5-1.4-1.9-1.51.4-1.71.9-0.7-1.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.90.2-0.20.20.10.10.20.00.50.10.01.0-0.8-0.40.7
Pavlov. Cond. response bias0.30.42.20.3-0.30.30.20.20.40.20.80.3-0.21.5-1.1-0.40.9
Pavlov. Cond. lever latency0.50.71.2-0.80.9-0.9-0.9-0.9-0.9-1.0-0.7-0.91.0-1.10.4-1.0-0.3
Pavlov. Cond. magazine entry latency0.50.60.8-0.90.9-0.9-0.9-0.9-0.9-0.9-0.8-0.80.6-0.20.6-0.8-0.8
Pavlov. Cond. change in total contacts0.20.40.70.5-0.60.60.70.70.60.70.40.7-0.80.8-0.10.8-0.1
Pavlov. Cond. index score0.00.10.50.0-0.10.10.10.10.10.20.00.1-0.30.70.10.2-0.2
Pavlov. Cond. latency score0.30.41.40.6-0.60.60.60.60.60.60.60.7-0.81.2-0.50.60.3
Pavlov. Cond. lever contacts0.40.51.00.6-0.70.70.80.80.80.80.60.8-0.81.0-0.30.80.3
Pavlov. Cond. magazine entry number0.20.30.60.6-0.50.50.50.50.50.40.70.5-0.20.2-0.70.20.8
Pavlov. Cond. intertrial magazine entries0.10.11.40.1-0.00.0-0.0-0.00.0-0.10.30.00.10.3-0.5-0.41.2
Pavlov. Cond. lever-magazine prob. diff.0.00.00.40.0-0.10.10.10.10.10.1-0.00.1-0.20.60.10.2-0.3
Pavlov. Cond. response bias0.00.10.2-0.20.0-0.00.00.0-0.00.1-0.30.0-0.10.30.50.3-0.5
Time in closed arm before self-admin1.72.23.91.6-1.51.51.71.71.61.71.11.6-1.80.4-0.52.00.7
Time in closed arm after self-admin0.60.60.90.7-0.90.90.80.80.90.80.80.9-0.9-0.0-0.70.70.7
Time in open arm before self-admin0.50.52.7-0.10.0-0.0-0.3-0.3-0.1-0.40.6-0.20.51.6-1.3-1.20.7
Time in open arm after self-admin0.30.30.5-0.50.7-0.7-0.6-0.6-0.6-0.6-0.5-0.60.6-0.10.3-0.6-0.2
Bone: periosteal estimation6.012.615.84.0-3.73.73.73.73.83.73.63.8-3.82.9-3.03.22.8
Bone: periosteal perimeter6.511.213.03.6-3.43.43.43.43.43.33.53.5-3.53.3-3.22.63.2
Bone: post-yield work0.91.32.71.1-1.21.21.21.21.31.21.11.1-1.10.8-0.91.01.6
Progressive ratio test 1 active lever presses0.20.31.00.6-0.50.50.50.50.50.50.50.5-0.41.0-0.40.40.3
Progressive ratio test 1 breakpoint0.20.30.80.6-0.50.50.50.50.50.50.40.5-0.40.9-0.30.50.2
Progressive ratio test 1 inactive lever presses0.60.91.7-0.81.2-1.2-1.1-1.1-1.0-1.1-0.9-1.01.3-0.30.6-1.00.0
Progressive ratio test 2 active lever presses0.10.10.30.5-0.30.30.40.40.30.40.20.4-0.30.00.00.6-0.1
Progressive ratio test 2 breakpoint0.10.10.30.5-0.30.30.40.40.30.40.20.4-0.30.00.00.6-0.1
Progressive ratio test 2 inactive lever presses0.00.10.2-0.10.1-0.1-0.2-0.2-0.1-0.20.10.00.40.3-0.3-0.40.3
Incentive Sensitization - Responses0.10.10.6-0.10.3-0.3-0.1-0.1-0.3-0.1-0.2-0.1-0.1-0.80.30.0-0.5
Incentive Sensitization - Breakpoint0.10.10.50.10.1-0.10.10.1-0.10.1-0.00.1-0.3-0.70.20.2-0.4
Sum of active levers in priming session hrs 5-60.00.00.2-0.20.0-0.00.00.0-0.20.0-0.20.2-0.1-0.50.20.1-0.2
Progressive ratio0.00.00.20.1-0.10.10.20.20.10.10.40.10.10.0-0.4-0.00.2
Food seeking constrained by brief footshock8.110.012.43.5-3.43.43.53.53.43.52.73.2-3.42.9-1.83.51.9
Seeking ratio, punishment vs. effort1.11.52.91.4-1.31.31.31.41.31.40.71.2-1.51.0-0.21.70.5
Retroperitoneal fat weight1.04.36.7-1.92.0-2.0-1.8-1.8-2.0-1.7-2.3-2.22.1-2.62.5-0.8-2.6
Reaction time number correct0.61.11.91.4-1.01.01.21.11.01.11.21.2-1.00.7-1.00.91.1
Reaction time mean minus median0.71.72.6-1.61.4-1.4-1.4-1.4-1.4-1.4-1.5-1.41.2-0.71.3-1.1-1.1
Reaction time mean minus median AUC0.51.21.5-1.21.2-1.2-1.1-1.1-1.2-1.1-1.2-1.21.1-0.61.2-0.8-1.0
Reaction time num false alarms0.30.40.90.8-0.60.60.60.60.60.60.20.2-0.3-0.90.30.9-0.8
Reaction time num false alarms AUC0.30.40.90.9-0.70.70.70.70.60.70.30.4-0.4-0.60.11.0-0.7
Reaction time trials correct on left0.61.11.91.4-1.01.01.21.11.01.11.21.2-1.00.7-1.00.91.1
Reaction time trials on left0.71.32.11.5-1.11.11.21.21.11.21.31.3-1.10.8-1.20.91.2
Reaction time mean0.10.10.70.1-0.30.30.30.30.30.30.20.5-0.50.8-0.10.40.2
Reaction time mean AUC0.10.11.00.1-0.20.20.20.20.20.20.20.5-0.41.0-0.20.20.3
Median of all reaction times0.50.71.60.7-0.80.80.90.90.90.90.71.1-1.01.3-0.60.80.6
Reaction time omissions1.01.53.30.9-1.21.21.01.01.20.91.41.0-1.21.8-1.60.41.5
Reaction time false alarm rate0.20.31.2-0.20.2-0.2-0.3-0.3-0.3-0.3-0.5-0.50.5-1.00.6-0.0-1.1
Reaction time premature initiation rate0.10.10.40.2-0.20.20.30.30.20.30.30.7-0.60.3-0.30.20.2
Reaction time premature initiations0.61.12.01.2-1.01.01.11.10.91.11.11.4-1.30.8-1.00.90.9
Std. dev. reaction times0.40.71.2-1.10.8-0.8-0.8-0.8-0.8-0.8-1.0-0.70.6-0.61.0-0.5-1.0
Reaction time trials completed0.71.32.11.5-1.11.11.21.21.11.21.31.3-1.10.8-1.20.91.2
Reaction time trials AUC0.61.21.91.4-1.01.01.21.21.01.21.21.2-1.00.7-1.00.91.1
Run reversals in cocaine runway, females0.10.10.50.1-0.10.10.10.10.20.10.40.4-0.30.7-0.5-0.1-0.0
Run reversals in cocaine runway, males0.40.40.7-0.60.8-0.8-0.7-0.7-0.8-0.7-0.9-0.30.5-0.50.8-0.4-0.2
Latency to leave start box in cocaine runway0.91.03.31.0-0.60.60.70.70.80.61.21.0-1.01.1-1.50.01.8
Latency to leave start box in cocaine runway, F0.50.61.80.7-0.60.60.60.60.70.50.90.6-0.80.5-1.10.11.3
Latency to leave start box in cocaine runway, M0.20.20.90.40.1-0.10.20.20.10.10.50.3-0.30.8-0.7-0.20.9
Std. dev. time between licks in bursts0.50.71.11.1-0.80.80.90.90.80.90.71.0-1.10.2-0.60.90.3
Total sessions with >9 infusions0.00.00.20.0-0.00.00.10.10.10.10.10.1-0.10.5-0.10.0-0.3
Short access day 1 total inactive lever presses0.10.20.8-0.50.0-0.0-0.2-0.2-0.2-0.2-0.7-0.10.2-0.20.90.3-0.9
Short access day 10 total inactive lever presses0.92.23.6-1.21.2-1.2-1.4-1.4-1.3-1.3-1.8-1.51.7-1.81.9-0.7-1.8
Short access day 1 total infusions0.40.50.7-0.80.7-0.7-0.8-0.8-0.7-0.7-0.8-0.70.8-0.40.7-0.6-0.8
Short access day 10 total infusions0.10.21.00.3-0.30.30.30.30.30.40.40.4-0.11.0-0.40.20.1
Short access total infusions0.10.10.40.3-0.40.40.30.30.40.40.20.3-0.20.6-0.10.40.1
Short access day 1 locomotion0.40.51.6-0.80.9-0.9-0.8-0.8-0.7-0.9-0.2-0.70.6-0.1-0.3-1.3-0.1
Short access day 10 total locomotion0.20.42.00.2-0.30.30.10.10.1-0.00.90.0-0.11.1-1.4-0.80.9
Short access total locomotion0.20.31.30.1-0.10.10.00.00.1-0.00.70.1-0.01.0-1.1-0.70.6
One hour access (0.3 mA shock)0.10.20.70.3-0.20.20.30.30.20.4-0.20.3-0.20.00.70.8-0.6
Compulsive drug intake0.20.20.9-0.40.2-0.2-0.1-0.1-0.3-0.1-0.5-0.30.4-0.90.80.3-0.7
One hour access (shock baseline)0.20.30.60.6-0.50.50.50.50.50.50.40.6-0.60.8-0.40.40.3
Social response proportion3.43.97.1-1.82.0-2.0-1.7-1.7-1.9-1.6-2.3-2.01.8-2.72.5-0.7-2.4
Social responses0.50.62.70.20.3-0.3-0.1-0.1-0.10.0-0.9-0.40.3-1.61.50.8-1.3
Social time0.10.20.9-0.3-0.00.0-0.2-0.2-0.2-0.2-0.4-0.40.4-1.00.60.1-0.5
Soleus weight2.06.07.72.5-2.52.52.42.32.42.32.72.5-2.42.8-2.71.52.7
Bone: stiffness0.61.11.41.1-1.11.11.11.11.21.11.11.1-1.00.9-0.90.90.8
Tibialis anterior weight6.522.130.35.3-5.25.25.35.35.25.44.15.1-5.02.7-2.65.52.2
Time to tail flick, vehicle, before self-admin0.10.10.4-0.60.1-0.1-0.3-0.3-0.0-0.3-0.0-0.40.4-0.2-0.2-0.50.6
Time to tail flick, vehicle, after self-admin0.50.62.10.6-0.70.70.50.50.70.40.90.4-0.41.5-1.1-0.01.2
Time to tail flick, test, before self-admin0.40.40.90.6-0.80.80.70.70.80.70.40.7-0.9-0.3-0.20.8-0.1
Time to tail flick, test, after self-admin1.51.62.31.5-1.31.31.31.31.41.31.41.2-1.40.8-1.21.01.0
Delta time to tail flick, vehicle, before/after SA0.20.20.70.6-0.20.20.40.30.30.30.60.3-0.30.8-0.70.00.6
Delta time to tail flick, test, before/after SA0.20.21.00.10.2-0.2-0.1-0.1-0.1-0.20.4-0.20.21.0-0.7-0.60.7
Tibia length1.43.84.42.1-2.02.02.02.02.02.02.02.0-1.91.9-1.71.62.0
Ambulatory time before self-admin0.10.20.4-0.40.4-0.4-0.4-0.4-0.5-0.4-0.5-0.20.5-0.60.5-0.2-0.7
Ambulatory time after self-admin0.00.00.2-0.20.2-0.2-0.2-0.2-0.0-0.1-0.4-0.2-0.10.10.40.10.1
Bone: tissue strength0.70.71.8-0.80.8-0.8-0.8-0.8-0.9-0.8-0.9-0.80.8-1.30.9-0.6-0.8
Total heroin consumption0.40.51.60.4-0.80.80.60.50.50.51.00.7-0.80.8-1.2-0.10.5
Bone: trabecular number0.20.41.00.4-0.40.40.50.40.40.40.80.7-0.70.9-1.0-0.00.6
Bone: trabecular spacing0.70.93.20.8-1.01.01.01.00.91.10.10.8-0.8-0.60.71.8-0.8
Bone: trabecular thickness0.40.52.00.2-0.20.20.10.10.2-0.00.90.3-0.31.1-1.4-0.71.2
Bone: trabecular tissue density3.85.69.5-2.12.3-2.3-2.2-2.1-2.1-2.0-2.9-2.42.3-3.03.1-0.9-2.7
Water consumed over 24 hours1.62.23.11.6-1.51.51.41.41.61.41.71.3-1.31.7-1.70.81.6
Number of responses in last shaping day2.32.63.31.5-1.71.71.81.81.81.71.71.7-1.60.8-1.31.51.6