Hub : Genes

Slc35a1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Slc35a1 0.2 0.13 2.0e-03 0.09 0.08 0.08 0.08 3.5e-03 4.9e-03 4.8e-03 5.0e-03
2 Brain intron excision ratio chr5_49226632_49230692 0.04 0.03 1.2e-03 0.02 0.02 0.02 0.02 5.3e-03 4.5e-03 5.9e-03 6.1e-03
3 NAcc intron excision ratio chr5_49230826_49231247 0.03 0.02 1.3e-03 0.03 0.01 0.01 0.03 6.7e-05 6.7e-03 1.0e-02 2.2e-04
4 Adipose gene expression Slc35a1 0.1 0.07 6.3e-10 0.06 0.06 0.06 0.06 3.5e-07 2.2e-07 5.7e-07 2.4e-07
5 BLA mRNA stability Slc35a1 0.08 0.06 1.0e-03 0.02 0.03 0.01 0.02 2.5e-02 6.9e-03 8.2e-02 2.1e-02
6 Adipose mRNA stability Slc35a1 0.05 0.03 1.8e-05 0.03 0.03 0.03 0.03 1.6e-04 1.5e-04 1.4e-04 1.3e-04
7 NAcc mRNA stability Slc35a1 0.03 0.02 1.1e-03 0.01 0.02 0 0.01 1.7e-02 5.2e-03 1.5e-01 4.3e-02
8 NAcc intron excision ratio chr5_49231423_49233546 0.03 0.03 5.9e-04 0.02 0.02 0.02 0.02 5.1e-03 9.0e-04 2.5e-03 1.6e-03
9 NAcc intron excision ratio chr5_49226632_49230692 0.04 0.04 2.4e-04 0.02 0.03 0.03 0.03 2.9e-03 1.9e-04 3.1e-04 5.0e-04
10 Brain mRNA stability Slc35a1 0.1 0.08 4.0e-07 0.06 0.06 0.06 0.05 6.2e-06 2.9e-06 1.9e-06 1.1e-05
11 Liver gene expression Slc35a1 0.12 0.08 2.1e-12 0.09 0.09 0.08 0.08 7.5e-10 1.1e-09 5.9e-09 1.2e-09
12 PL mRNA stability Slc35a1 0.04 0.03 2.3e-04 0.02 0.04 0.03 0.03 4.7e-03 6.4e-05 8.4e-04 5.3e-04
13 PL intron excision ratio chr5_49231423_49233546 0.02 0.02 7.2e-03 0 0.01 0.01 0.01 1.1e-01 1.7e-02 7.0e-03 1.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.40.61.41.0-0.8-0.90.81.20.80.50.5-0.5-0.5-0.70.2-1.1
Area under the delay curve0.00.00.0-0.0-0.0-0.10.0-0.00.20.00.0-0.00.00.20.0-0.1
BMI with tail3.411.016.33.4-3.4-3.23.42.33.23.73.8-3.8-3.4-3.54.00.0
BMI without tail2.45.07.22.7-2.4-2.42.42.52.32.22.2-2.2-2.3-2.41.8-0.8
Body weight6.025.228.75.4-5.3-5.25.34.75.35.25.2-5.2-5.2-5.34.9-2.0
Weight adjusted by age2.32.63.41.8-1.7-1.71.71.81.71.51.5-1.4-1.5-1.71.2-1.5
Bone surface1.22.14.81.8-1.5-1.71.52.21.51.11.1-1.0-1.3-1.50.4-1.5
Bone volume0.50.82.41.1-0.9-1.10.81.60.90.50.4-0.4-0.6-0.8-0.1-1.3
Breakpoint value in progressive ratio session0.10.10.30.0-0.0-0.2-0.00.5-0.0-0.2-0.30.30.1-0.1-0.6-0.4
Number of licking bursts0.20.20.4-0.30.50.4-0.4-0.2-0.4-0.5-0.50.50.30.2-0.6-0.6
Context. condit. distance diff. score0.80.91.9-0.81.01.0-0.9-1.1-1.1-0.8-0.80.70.81.1-0.51.4
Locomotion velocity, session 10.10.10.3-0.30.30.3-0.3-0.5-0.2-0.1-0.10.10.2-0.00.10.4
Locomotion distance, session 13.54.55.6-2.02.32.4-2.3-2.3-2.1-2.2-2.22.12.32.3-1.9-0.3
Locomotion velocity, session 20.10.10.20.0-0.10.10.1-0.40.30.20.2-0.3-0.10.10.5-0.4
Locomotion distance, session 24.25.99.9-2.62.72.8-2.7-3.1-2.7-2.3-2.32.22.42.5-1.60.1
Locomotion velocity, session 31.82.14.1-1.61.51.6-1.5-2.0-1.6-1.2-1.11.11.41.6-0.61.4
Locomotion distance, session 32.42.75.6-1.61.71.8-1.7-2.4-1.8-1.3-1.21.11.52.0-0.61.7
Stereotopy head waving bouts, day 30.60.71.51.0-0.9-0.90.81.20.90.60.6-0.6-0.8-0.80.3-1.2
Stereotopy head waving duration, day 31.82.22.71.7-1.6-1.61.51.51.51.51.5-1.4-1.6-1.51.3-0.8
Locomotion velocity, session 70.30.31.6-0.40.60.8-0.6-1.3-0.6-0.3-0.20.20.30.50.20.2
Locomotion distance, session 71.21.53.7-1.11.41.5-1.4-1.9-1.5-1.0-1.00.91.11.3-0.50.7
Stereotopy head waving bouts, day 71.01.12.60.8-0.9-0.80.90.20.61.21.3-1.3-1.2-0.51.61.2
Stereotopy head waving duration, day 72.42.94.61.6-1.7-1.61.81.11.62.02.0-2.0-1.9-1.52.10.9
Locomotion velocity, session 83.34.08.7-2.22.12.2-2.0-2.9-2.3-1.5-1.51.31.72.3-0.62.1
Locomotion distance, session 85.88.413.0-3.03.13.3-3.1-3.6-3.3-2.7-2.72.62.93.3-1.91.8
Degree of sensitization distance0.50.50.70.7-0.7-0.70.70.50.60.70.7-0.7-0.8-0.90.7-0.2
Degree of sensitization stereotypy1.11.23.30.7-0.8-0.70.8-0.20.51.31.3-1.4-1.1-0.51.81.8
Conditioned locomotion0.10.10.60.2-0.1-0.20.10.40.3-0.0-0.00.1-0.10.2-0.2-0.8
Cocaine response after cond. corrected0.80.91.31.1-0.9-0.90.90.90.80.90.9-0.9-1.0-1.10.7-1.1
Cocaine response after cond. not corrected0.30.31.30.7-0.5-0.50.50.60.50.50.5-0.5-0.5-0.50.3-1.1
Cocaine response before conditioning0.10.10.5-0.10.30.3-0.3-0.4-0.2-0.2-0.20.20.40.7-0.1-0.1
Saline control response1.11.52.91.2-1.3-1.41.31.71.31.01.0-0.9-1.1-1.30.5-1.2
Bone: connectivity density0.91.32.11.3-1.2-1.21.21.41.31.00.9-0.9-1.1-1.50.7-1.2
Bone: cortical apparent density0.20.20.40.10.40.3-0.4-0.2-0.5-0.5-0.50.50.40.6-0.60.4
Bone: cortical area3.35.07.42.7-2.4-2.52.42.52.42.22.2-2.2-2.1-1.91.8-1.1
Bone: cortical porosity0.30.32.3-0.0-0.0-0.2-0.00.70.3-0.4-0.40.50.40.2-0.9-1.5
Bone: cortical porosity0.50.51.40.8-0.7-0.80.71.10.90.40.4-0.4-0.3-0.50.1-1.2
Bone: cortical thickness0.81.32.81.7-1.2-1.31.21.31.21.11.1-1.1-1.0-0.70.9-0.6
Bone: cortical thickness0.50.61.21.0-0.7-0.70.70.30.60.90.9-1.0-0.7-0.51.10.5
Bone: cortical tissue density0.10.20.40.10.40.3-0.4-0.1-0.5-0.5-0.50.50.40.5-0.70.4
Condit. Reinf. active minus inactive responses2.32.53.7-1.61.71.8-1.7-1.9-1.6-1.5-1.51.41.61.6-1.11.6
Condit. Reinf. active-inactive response ratio0.70.81.2-0.90.90.9-0.9-0.9-0.8-0.8-0.80.80.90.9-0.71.1
Condit. Reinf. active responses1.31.62.9-1.11.31.4-1.3-1.7-1.3-1.1-1.11.01.21.3-0.71.4
Condit. Reinf. inactive responses0.50.61.3-0.50.80.9-0.8-1.1-0.9-0.6-0.60.60.70.8-0.30.7
Incentive salience index mean0.70.91.6-0.81.01.1-1.0-1.3-0.9-0.8-0.80.80.81.0-0.51.2
Condit. Reinf. lever presses0.00.10.20.30.00.1-0.0-0.40.10.10.2-0.2-0.30.00.40.4
Condit. Reinf. active minus inactive responses0.60.71.10.7-0.8-0.70.80.41.00.90.9-0.9-0.9-1.11.1-0.8
Condit. Reinf. active-inactive response ratio0.50.51.70.3-0.4-0.30.5-0.40.50.80.8-0.9-0.8-0.91.30.3
Condit. Reinf. active responses0.70.93.41.0-0.9-0.90.90.91.20.70.7-0.7-0.8-0.70.6-1.9
Condit. Reinf. inactive responses0.40.54.00.6-0.5-0.60.51.00.70.10.1-0.1-0.20.1-0.3-2.0
Condit. Reinf. lever presses1.41.93.21.5-1.4-1.41.41.21.81.41.4-1.4-1.4-1.21.4-0.6
Condit. Reinf. lever reinforcers received1.01.54.31.3-1.2-1.11.21.21.41.01.0-1.0-1.0-1.00.8-2.1
Conditioned reinforcement - actives0.40.40.80.3-0.6-0.40.60.20.50.70.7-0.7-0.5-0.60.90.7
Conditioned reinforcement - inactives0.10.11.1-0.30.00.3-0.0-0.30.2-0.00.0-0.00.1-0.20.2-1.0
Conditioned locomotion0.50.60.90.6-0.8-0.70.80.70.80.90.9-0.8-0.9-0.90.9-0.0
Patch foraging indifference point 0 sec0.10.20.50.5-0.6-0.60.50.70.50.40.4-0.4-0.3-0.20.2-0.6
Patch foraging indifference point AUC1.71.92.71.7-1.4-1.51.41.41.41.41.4-1.4-1.3-1.51.2-0.7
Delay disc. indifference point, 0s delay0.20.20.7-0.50.40.3-0.4-0.6-0.4-0.3-0.30.20.40.7-0.10.8
Delay disc. indifference point, 16s delay0.10.10.40.4-0.2-0.10.20.20.50.20.2-0.2-0.2-0.10.2-0.7
Delay disc. indifference point, 2s delay0.10.10.30.4-0.3-0.50.30.50.30.30.3-0.3-0.2-0.20.1-0.3
Delay disc. indifference point, 24s delay0.00.00.10.2-0.0-0.30.00.10.00.10.1-0.10.00.10.0-0.1
Delay disc. indifference point, 4s delay0.20.30.5-0.70.50.5-0.5-0.6-0.4-0.5-0.50.40.50.5-0.40.4
Delay disc. indifference point, 8s delay0.00.00.1-0.30.10.0-0.1-0.10.1-0.2-0.20.20.20.2-0.2-0.3
Indifference point function ln k0.40.61.2-1.10.70.9-0.7-0.9-0.6-0.7-0.70.70.70.9-0.40.4
Indifference point function log k0.40.61.2-1.10.70.9-0.7-0.9-0.6-0.7-0.70.70.70.9-0.40.4
Patch foraging total patch changes 0 sec0.10.20.20.4-0.5-0.40.50.50.40.40.4-0.4-0.3-0.10.4-0.3
Patch foraging total patch changes 12 sec1.82.33.71.5-1.6-1.51.60.91.51.71.7-1.8-1.6-1.31.90.3
Patch foraging total patch changes 18 sec0.30.41.11.0-0.7-0.80.70.70.50.60.6-0.7-0.4-0.40.50.0
Patch foraging total patch changes 24 sec1.41.82.51.5-1.4-1.61.41.61.31.31.2-1.2-1.2-1.20.9-1.2
Patch foraging total patch changes 6 sec0.50.71.30.8-0.9-0.90.91.00.90.70.7-0.7-0.6-0.80.5-1.2
Patch foraging time to switch 0 sec1.82.83.2-1.81.81.8-1.8-1.6-1.6-1.8-1.81.81.71.7-1.70.6
Patch foraging water rate 0 sec1.42.22.61.6-1.6-1.61.61.51.61.61.6-1.6-1.4-1.31.4-0.5
Patch foraging water rate 12 sec0.30.40.60.8-0.6-0.60.70.50.50.70.8-0.8-0.5-0.10.8-0.4
Patch foraging water rate 18 sec0.50.62.10.9-0.6-0.50.6-0.20.41.01.0-1.1-0.7-0.11.40.4
Patch foraging water rate 24 sec0.30.42.70.3-0.10.10.2-0.70.10.50.6-0.6-0.10.51.11.6
Patch foraging water rate 6 sec0.71.01.91.3-1.0-1.01.00.60.91.21.2-1.3-1.0-0.51.40.2
Seeking ratio, delayed vs. immediate footshock0.10.10.5-0.0-0.0-0.10.00.20.4-0.1-0.10.20.0-0.3-0.2-0.7
Distance traveled before self-admin0.60.61.60.1-0.7-0.60.70.10.50.90.9-1.0-0.7-0.51.21.3
Distance traveled after self-admin0.10.10.6-0.1-0.0-0.10.1-0.3-0.10.20.2-0.3-0.00.40.40.8
Extensor digitorum longus weight4.015.920.84.6-4.2-4.24.23.94.34.14.1-4.0-4.2-4.03.7-1.3
Bone: elastic displacement0.30.31.1-0.40.40.4-0.5-0.0-0.4-0.6-0.60.70.60.3-0.9-1.0
Bone: elastic work1.21.63.01.4-1.3-1.41.31.71.41.01.0-0.9-1.0-1.20.6-1.6
Bone: endosteal estimation4.19.010.83.2-3.3-3.33.33.13.23.23.1-3.1-3.0-2.72.9-0.4
Bone: endosteal perimeter2.75.57.12.4-2.6-2.72.62.62.52.42.4-2.3-2.3-2.32.0-0.8
Epididymis fat weight0.30.62.8-0.30.40.3-0.40.5-0.3-0.8-0.80.90.7-0.1-1.3-1.7
Delta time in closed arm before/after self-admin0.20.20.2-0.40.40.3-0.4-0.3-0.5-0.4-0.40.50.40.2-0.50.3
Delta time in open arm before/after self-admin0.10.10.30.2-0.2-0.00.2-0.20.30.40.4-0.4-0.3-0.10.60.1
Diff in mean of infusions in LGA sessions0.50.51.1-0.70.70.6-0.7-0.3-0.7-0.9-0.90.90.80.5-1.1-0.4
Delay discount exponential model param0.00.00.00.1-0.10.00.10.1-0.10.10.1-0.1-0.2-0.20.10.1
Extinction: sum of active levers before priming0.50.52.0-0.80.60.6-0.6-1.0-0.6-0.4-0.40.40.50.6-0.11.4
Active lever presses in extinction session 60.80.81.7-1.00.90.7-0.9-0.4-0.8-1.1-1.11.10.90.7-1.3-0.4
Bone: final force2.33.85.32.1-2.2-2.32.22.32.22.02.0-2.0-1.8-1.51.6-0.4
Bone: final moment3.04.97.02.4-2.5-2.62.52.62.52.32.2-2.2-2.0-1.81.8-0.5
Food consumed during 24 hour testing period1.61.92.61.4-1.5-1.61.51.51.51.41.4-1.4-1.6-1.21.20.5
Glucose0.00.10.60.1-0.1-0.20.20.20.00.20.2-0.2-0.3-0.20.10.7
Heart weight0.71.01.51.2-1.1-1.11.11.10.91.01.0-1.0-0.9-0.70.8-0.2
Delay discount hyperbolic model param0.00.00.00.1-0.10.00.10.1-0.00.10.1-0.1-0.1-0.20.0-0.1
Intermittent access intake day 1-15 change3.13.15.3-2.31.91.9-1.9-2.1-1.6-1.7-1.71.61.61.9-1.31.0
Intermittent access intake escalation2.62.54.4-2.11.71.7-1.7-1.9-1.3-1.6-1.61.51.41.7-1.20.8
Intermittent access intake escalation 21.11.12.2-1.41.11.2-1.1-1.5-0.7-1.0-1.00.90.81.1-0.60.9
Intermitt. access day 1 inactive lever presses0.40.40.9-0.40.80.6-0.7-0.8-0.9-0.6-0.50.50.80.8-0.40.3
Intermitt. access day 15 inactive lever presses2.22.43.1-1.81.71.5-1.6-1.4-1.2-1.7-1.71.61.61.6-1.6-1.1
Intermitt. access escalation Index0.10.00.2-0.00.20.1-0.2-0.0-0.0-0.2-0.30.30.20.0-0.30.4
Intermittent access day 1 total infusions2.02.32.91.4-1.6-1.51.61.61.61.51.5-1.5-1.6-1.71.2-1.1
Intermittent access day 15 total infusions0.10.10.4-0.0-0.3-0.30.30.10.60.40.4-0.4-0.6-0.40.50.1
Intermittent access terminal intake (last 3 days)0.00.00.1-0.30.00.0-0.0-0.00.30.00.0-0.0-0.3-0.20.0-0.3
Intermittent access total infusions1.41.62.61.0-1.3-1.11.31.11.51.31.3-1.3-1.6-1.51.2-0.6
Intermittent access day 1 locomotion0.20.20.90.3-0.4-0.50.40.90.20.20.2-0.2-0.3-0.5-0.2-1.0
Intermittent access day 15 total locomotion0.20.21.4-0.1-0.2-0.20.20.60.20.10.1-0.1-0.2-0.4-0.2-1.2
Intermittent access total locomotion0.40.51.00.4-0.7-0.70.71.00.70.60.5-0.5-0.7-0.90.3-0.8
Intermittent access standard deviation1.01.12.5-1.61.21.2-1.1-1.6-0.7-0.9-0.90.80.81.0-0.50.6
Left kidney weight2.98.111.33.4-3.0-3.13.02.82.83.03.0-3.0-3.0-2.62.8-0.7
Right kidney weight2.77.79.93.2-2.9-2.82.92.62.92.92.9-2.9-3.0-2.62.7-0.9
Cocaine induced anxiety0.10.21.0-0.70.20.2-0.2-0.3-0.4-0.2-0.20.20.30.2-0.11.0
Post-drug Anxiety0.10.10.7-0.1-0.3-0.30.30.30.10.30.2-0.2-0.1-0.20.20.8
Baseline Anxiety0.00.00.20.2-0.1-0.10.10.20.30.00.0-0.0-0.1-0.0-0.1-0.5
Tail length0.62.05.31.7-1.4-1.51.42.31.50.90.9-0.8-1.2-1.40.1-1.8
Length with tail2.28.012.13.1-3.0-3.03.03.53.12.62.5-2.5-2.8-3.01.8-2.5
Length without tail2.04.35.51.9-2.2-2.22.21.62.22.32.3-2.3-2.1-2.12.3-0.9
Times rat made contact with spout0.10.10.20.2-0.0-0.10.00.40.1-0.1-0.10.2-0.2-0.1-0.4-0.5
Lifetime Intake1.41.52.41.0-1.2-1.11.21.01.51.31.3-1.3-1.6-1.41.2-0.6
Liver weight, left0.40.73.40.10.40.1-0.41.0-0.2-1.0-1.01.10.70.2-1.8-0.7
Liver weight, right0.20.41.30.10.40.2-0.40.4-0.4-0.7-0.70.70.30.1-1.1-1.2
Locomotor activity0.61.02.0-1.40.90.7-0.9-0.8-1.3-0.9-0.90.91.11.0-0.80.6
Locomotor testing distance0.30.51.3-0.90.70.5-0.7-0.5-1.2-0.7-0.70.70.90.7-0.70.4
Locomotor testing rearing0.71.12.0-1.11.00.9-1.0-1.0-1.4-0.9-0.90.91.31.2-0.80.6
Locomotion in novel chamber0.70.81.61.0-1.0-0.81.01.11.10.80.8-0.7-0.9-1.30.6-0.7
Locomotion in novel chamber post-restriction0.70.81.5-1.00.90.8-0.9-0.5-0.6-1.1-1.11.11.10.9-1.2-0.0
Fecal boli incidents, locomotor time 10.10.10.40.10.0-0.2-0.00.40.2-0.2-0.20.2-0.2-0.1-0.5-0.6
Change in fecal boli incidents, locomotor task0.30.30.6-0.30.30.5-0.4-0.0-0.2-0.6-0.60.60.70.4-0.7-0.8
Time >=10cm from walls, locomotor time 10.10.10.80.1-0.2-0.10.20.10.50.20.2-0.2-0.3-0.30.2-0.9
Bouts of movement, locomotor time 10.30.30.4-0.60.60.6-0.6-0.6-0.5-0.6-0.60.60.60.5-0.60.5
Total resting periods, locomotor time 10.20.20.5-0.30.40.2-0.4-0.1-0.3-0.5-0.50.60.40.3-0.7-0.0
Rest time, locomotor task time 10.50.60.9-0.80.90.7-0.9-0.6-0.7-0.9-0.90.90.50.6-0.90.4
Distance moved, locomotor task time 10.60.61.30.6-0.8-0.50.80.30.50.90.9-1.0-0.6-0.51.11.1
Vertical activity count, locomotor time 10.30.31.80.1-0.30.10.3-0.10.10.50.5-0.6-0.2-0.20.81.3
Time >=10cm from walls, locomotor time 21.61.72.11.4-1.4-1.41.31.41.41.21.2-1.2-1.3-1.31.0-1.2
Bouts of movement, locomotor time 20.00.00.10.1-0.10.00.10.10.10.10.1-0.1-0.2-0.30.00.2
Total resting periods, locomotor time 20.00.00.1-0.00.00.1-0.00.00.0-0.0-0.00.0-0.1-0.2-0.10.3
Rest time, locomotor task time 20.50.60.9-1.00.80.9-0.9-0.6-0.6-0.9-1.01.00.60.4-1.0-0.1
Distance moved, locomotor task time 20.50.53.80.1-0.3-0.20.3-0.4-0.00.60.7-0.7-0.20.11.12.0
Vertical activity count, locomotor time 21.01.12.60.8-1.0-0.61.00.30.71.31.3-1.3-0.9-0.61.61.5
Light reinforcement 12.13.76.02.1-1.9-1.81.91.21.62.22.3-2.3-2.2-1.72.50.7
Light reinforcement 22.12.84.02.0-1.7-1.61.71.31.71.91.9-1.9-1.8-1.51.90.1
Bone: marrow area4.29.010.93.2-3.3-3.33.33.13.23.23.2-3.1-3.0-2.72.9-0.4
Bone: maximum diameter3.15.88.82.7-2.6-2.82.63.02.72.32.3-2.2-2.3-2.21.7-1.2
Bone: maximum force3.25.57.12.5-2.6-2.72.62.52.42.52.5-2.5-2.3-1.92.2-0.5
Bone: maximum moment3.56.18.02.7-2.7-2.82.72.82.62.62.6-2.5-2.3-2.12.2-0.6
Mean time between licks in bursts0.30.50.90.6-0.7-0.70.70.61.00.70.7-0.7-0.7-0.40.7-0.6
Mean num. licks in bursts0.10.10.20.3-0.4-0.40.40.50.50.30.3-0.3-0.3-0.30.30.2
Cd content in liver0.60.71.01.0-0.9-0.90.90.70.60.91.0-1.0-0.6-0.60.90.0
Co content in liver0.40.40.90.9-0.7-0.90.70.90.70.60.6-0.6-0.5-0.30.4-0.3
Cu content in liver0.40.51.2-0.70.70.7-0.7-0.3-0.6-0.9-0.90.90.90.4-1.1-0.2
Fe content in liver0.70.98.40.4-0.3-0.40.31.10.5-0.1-0.20.2-0.1-0.6-0.7-2.9
K content in liver2.02.02.5-1.51.41.5-1.4-1.3-1.6-1.4-1.41.41.61.2-1.31.0
Mg content in liver0.10.10.3-0.40.30.4-0.3-0.3-0.5-0.3-0.30.30.50.2-0.30.6
Mn content in liver0.00.00.10.1-0.1-0.10.10.30.10.00.0-0.0-0.1-0.2-0.1-0.4
Na content in liver2.32.43.0-1.71.61.6-1.6-1.3-1.7-1.7-1.71.71.61.4-1.6-0.1
Rb content in liver0.30.40.7-0.50.70.6-0.6-0.3-0.8-0.7-0.70.80.60.6-0.90.5
Se content in liver2.73.34.7-2.01.91.9-1.9-1.5-1.9-1.9-1.91.92.21.7-1.9-0.4
Sr content in liver4.94.56.0-2.22.32.3-2.3-2.1-2.2-2.2-2.22.12.32.4-1.90.1
Zn content in liver0.50.60.90.9-0.8-0.80.80.60.80.90.9-0.9-0.6-0.61.00.1
Bone: minimum diameter1.52.93.61.9-1.9-1.91.91.71.71.81.8-1.8-1.5-1.51.7-0.6
Time in familiar zone, hab. session 11.31.21.71.3-1.1-1.21.11.21.01.11.1-1.1-1.2-1.20.9-0.7
Time in novel zone, hab. session 13.73.66.1-2.31.91.9-1.8-2.3-2.1-1.5-1.51.41.82.2-0.92.5
Total zone transitions, hab. session 19.413.216.4-3.43.93.7-3.9-3.0-3.9-4.0-4.04.03.83.5-4.1-0.6
Total locomotion distance, hab. session 17.110.115.4-2.73.33.1-3.3-2.1-3.1-3.6-3.63.73.33.1-3.9-1.5
Locomotion velocity, hab. session 15.57.813.3-2.22.82.7-2.9-1.6-2.5-3.2-3.33.32.82.5-3.7-2.3
Time in familiar zone, hab. session 20.10.11.40.2-0.00.10.0-0.30.10.10.1-0.2-0.2-0.20.4-1.2
Time in novel zone, hab. session 20.20.22.6-0.3-0.1-0.20.10.1-0.10.10.1-0.10.20.00.11.6
Total zone transitions, hab. session 24.05.16.7-2.42.52.5-2.5-2.4-2.6-2.3-2.32.32.32.2-2.00.6
Total locomotion distance, hab. session 21.82.33.6-1.31.51.5-1.5-1.0-1.4-1.7-1.81.81.61.3-1.9-1.4
Locomotion velocity, hab. session 21.52.03.5-1.11.41.3-1.4-0.7-1.2-1.6-1.61.71.41.2-1.9-1.6
Novel to familiar place preference ratio0.30.31.2-0.10.1-0.1-0.10.8-0.1-0.5-0.50.60.30.0-1.1-1.1
Novelty place preference0.60.62.0-0.50.50.3-0.50.5-0.5-0.8-0.90.90.70.3-1.4-1.0
Time in novel zone, NPP test0.60.72.2-0.70.60.4-0.60.3-0.6-0.9-1.01.00.80.4-1.5-0.8
Total zone transitions, NPP test2.63.75.5-2.32.12.1-2.1-2.2-2.3-1.8-1.81.71.81.9-1.40.7
Total locomotion distance, NPP test0.70.91.5-1.21.01.1-1.0-1.0-1.0-1.0-1.01.00.90.8-0.9-0.4
Locomotion velocity, NPP test0.40.60.9-0.90.80.8-0.8-0.7-0.7-0.8-0.80.80.60.7-0.7-0.7
Intraocular pressure1.41.93.31.2-1.6-1.61.51.81.71.31.2-1.2-1.2-1.70.9-0.6
Delta distance traveled before/after self-admin0.30.40.6-0.20.60.5-0.6-0.5-0.5-0.7-0.60.60.60.8-0.7-0.4
Delta ambulatory time before/after self-admin0.80.91.2-0.51.01.0-1.0-0.9-0.8-1.1-1.01.00.91.0-1.0-0.2
Parametrial fat weight0.81.52.6-1.11.31.6-1.3-1.6-1.2-1.1-1.11.11.51.4-0.70.6
Pavlov. Cond. lever latency0.20.20.7-0.80.40.5-0.4-0.6-0.4-0.3-0.30.30.40.3-0.10.6
Pavlov. Cond. magazine entry latency0.20.31.20.00.20.0-0.20.6-0.2-0.5-0.50.60.40.1-1.0-1.1
Pavlov. Cond. change in total contacts0.30.30.6-0.30.50.5-0.5-0.3-0.6-0.6-0.60.60.60.8-0.7-0.2
Pavlov. Cond. index score0.10.10.70.5-0.1-0.20.10.60.0-0.1-0.20.20.0-0.1-0.5-0.8
Pavlov. Cond. latency score0.20.20.90.7-0.3-0.40.30.80.20.10.0-0.0-0.2-0.4-0.3-1.0
Pavlov. Cond. lever contacts0.30.30.90.9-0.5-0.60.50.80.50.40.4-0.4-0.6-0.50.1-0.4
Pavlov. Cond. magazine entry number0.10.10.7-0.40.20.3-0.2-0.8-0.10.00.1-0.10.00.20.50.4
Pavlov. Cond. intertrial magazine entries1.51.83.4-1.31.41.6-1.4-1.8-1.3-1.2-1.11.11.41.7-0.70.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.70.4-0.1-0.20.10.5-0.0-0.1-0.10.20.0-0.0-0.5-0.8
Pavlov. Cond. response bias0.10.10.60.5-0.2-0.40.20.80.20.00.00.0-0.1-0.2-0.4-0.5
Pavlov. Cond. lever latency0.50.60.9-0.80.80.8-0.8-0.6-0.9-0.9-0.90.90.80.6-0.90.3
Pavlov. Cond. magazine entry latency0.80.91.2-0.91.01.1-1.0-0.9-0.7-1.0-1.01.01.10.9-0.9-0.3
Pavlov. Cond. change in total contacts0.30.40.70.7-0.7-0.50.70.40.80.70.7-0.7-0.7-0.70.8-0.2
Pavlov. Cond. index score0.00.00.30.2-0.1-0.00.1-0.00.30.10.1-0.1-0.0-0.10.2-0.6
Pavlov. Cond. latency score0.20.30.60.7-0.5-0.50.50.50.80.50.5-0.5-0.5-0.50.4-0.7
Pavlov. Cond. lever contacts0.30.50.60.7-0.7-0.60.70.50.80.70.7-0.7-0.7-0.60.7-0.6
Pavlov. Cond. magazine entry number0.20.30.60.5-0.6-0.70.60.80.40.60.5-0.5-0.5-0.40.40.0
Pavlov. Cond. intertrial magazine entries0.00.00.2-0.10.0-0.0-0.00.3-0.0-0.2-0.20.20.10.4-0.4-0.3
Pavlov. Cond. lever-magazine prob. diff.0.00.00.40.2-0.00.10.0-0.10.20.00.0-0.10.0-0.00.1-0.6
Pavlov. Cond. response bias0.00.00.10.00.00.10.0-0.20.10.10.1-0.1-0.00.00.2-0.4
Time in closed arm before self-admin4.55.16.12.2-2.4-2.42.42.12.22.52.5-2.4-2.3-2.42.40.3
Time in closed arm after self-admin1.01.01.80.9-1.1-1.11.11.10.91.01.0-0.9-0.9-1.30.80.4
Time in open arm before self-admin0.40.51.3-0.10.60.6-0.6-0.0-0.4-0.8-0.80.90.50.4-1.1-1.0
Time in open arm after self-admin0.40.40.7-0.50.70.8-0.7-0.7-0.5-0.6-0.60.60.50.9-0.5-0.2
Bone: periosteal estimation4.89.913.33.7-3.4-3.53.43.43.43.23.2-3.2-3.0-2.72.8-1.0
Bone: periosteal perimeter5.49.011.83.3-3.3-3.43.33.43.23.03.0-2.9-2.9-2.92.4-1.7
Bone: post-yield work0.91.21.81.3-1.2-1.31.21.31.01.11.1-1.1-1.1-0.90.9-0.1
Progressive ratio test 1 active lever presses0.40.42.60.5-0.4-0.30.40.50.60.30.3-0.3-0.6-0.50.2-1.6
Progressive ratio test 1 breakpoint0.30.32.70.3-0.2-0.20.20.40.50.10.2-0.2-0.4-0.30.0-1.7
Progressive ratio test 1 inactive lever presses1.01.11.5-0.91.11.2-1.1-0.9-0.8-1.1-1.11.11.10.9-1.1-1.2
Progressive ratio test 2 active lever presses1.01.11.40.9-1.1-1.01.11.01.11.11.1-1.1-1.2-1.21.0-0.3
Progressive ratio test 2 breakpoint1.21.31.61.1-1.2-1.11.21.11.21.21.2-1.2-1.2-1.31.1-0.4
Progressive ratio test 2 inactive lever presses0.10.10.6-0.80.40.3-0.4-0.4-0.1-0.3-0.30.30.30.1-0.3-0.2
Incentive Sensitization - Responses0.60.60.80.7-0.8-0.60.80.70.70.90.9-0.9-0.6-0.80.90.2
Incentive Sensitization - Breakpoint1.11.11.41.0-1.1-0.91.10.91.01.21.2-1.2-0.9-1.11.20.1
Sum of active levers in priming session hrs 5-60.20.20.30.5-0.4-0.30.40.20.50.50.5-0.5-0.5-0.50.60.5
Progressive ratio0.30.41.00.7-0.6-0.70.71.00.40.60.5-0.5-0.7-0.80.20.1
Food seeking constrained by brief footshock10.512.915.13.8-3.7-3.63.73.03.73.83.8-3.8-3.9-3.83.8-1.4
Seeking ratio, punishment vs. effort1.51.93.21.4-1.4-1.21.40.71.51.51.5-1.6-1.4-1.21.8-0.9
Retroperitoneal fat weight0.62.02.7-1.41.51.6-1.5-1.4-1.6-1.5-1.41.41.51.2-1.3-0.1
Reaction time number correct0.81.12.01.4-1.2-1.01.21.20.91.11.1-1.1-0.9-1.00.90.6
Reaction time mean minus median1.21.52.1-1.41.31.4-1.4-1.4-1.1-1.3-1.31.31.11.2-1.00.4
Reaction time mean minus median AUC0.81.01.5-1.01.11.2-1.1-1.2-1.0-1.0-1.01.00.81.1-0.80.6
Reaction time num false alarms0.60.81.60.8-0.8-0.80.80.40.31.00.9-1.0-0.8-1.11.11.3
Reaction time num false alarms AUC0.60.81.30.9-0.9-0.90.90.50.51.01.0-1.0-0.8-1.11.11.0
Reaction time trials correct on left0.81.12.01.4-1.2-1.01.21.20.91.11.1-1.1-0.9-1.00.90.6
Reaction time trials on left0.91.32.21.5-1.2-1.11.21.31.01.21.2-1.1-1.0-1.10.90.6
Reaction time mean0.10.20.50.2-0.4-0.20.40.20.60.30.3-0.3-0.4-0.70.4-0.6
Reaction time mean AUC0.10.20.90.1-0.3-0.20.20.30.60.20.2-0.2-0.3-0.60.2-1.0
Median of all reaction times0.70.91.80.8-1.0-0.90.90.91.20.90.9-0.8-1.0-1.30.8-1.0
Reaction time omissions0.50.61.30.8-0.8-0.90.71.11.00.50.4-0.4-0.6-1.10.1-1.1
Reaction time false alarm rate0.00.10.3-0.20.20.1-0.2-0.3-0.4-0.1-0.10.10.2-0.10.10.5
Reaction time premature initiation rate0.10.10.60.2-0.4-0.20.40.40.50.30.3-0.2-0.3-0.80.2-0.1
Reaction time premature initiations0.91.22.21.2-1.2-1.01.21.21.11.11.1-1.0-1.0-1.50.90.3
Std. dev. reaction times0.40.61.0-0.90.80.9-0.8-1.0-0.6-0.8-0.80.80.70.7-0.50.4
Reaction time trials completed0.91.32.21.5-1.2-1.11.21.31.01.21.2-1.1-1.0-1.10.90.6
Reaction time trials AUC0.91.32.11.4-1.2-1.11.21.31.01.21.2-1.1-1.0-1.01.00.7
Run reversals in cocaine runway, females0.40.30.80.4-0.6-0.60.60.70.70.50.4-0.4-0.6-0.80.3-0.9
Run reversals in cocaine runway, males0.60.61.0-1.00.90.9-0.9-1.0-0.6-0.8-0.80.80.90.7-0.60.1
Latency to leave start box in cocaine runway0.70.81.81.0-1.0-0.90.91.31.10.70.6-0.6-0.7-0.70.3-1.2
Latency to leave start box in cocaine runway, F0.40.51.30.8-0.8-0.70.71.10.70.50.5-0.4-0.5-0.70.1-0.7
Latency to leave start box in cocaine runway, M0.40.40.60.7-0.7-0.70.70.80.50.50.6-0.5-0.5-0.20.4-0.8
Std. dev. time between licks in bursts0.40.50.80.8-0.8-0.80.80.70.90.80.8-0.8-0.8-0.40.70.0
Total sessions with >9 infusions0.00.00.1-0.3-0.00.10.0-0.1-0.00.10.1-0.1-0.2-0.20.1-0.1
Short access day 1 total inactive lever presses0.30.30.8-0.90.60.6-0.6-0.9-0.4-0.4-0.40.40.50.4-0.20.6
Short access day 10 total inactive lever presses0.70.81.2-0.71.01.0-0.9-1.1-1.0-0.8-0.80.71.01.0-0.6-0.0
Short access day 1 total infusions0.70.71.0-1.00.91.0-0.9-1.0-0.8-0.8-0.80.80.70.8-0.70.4
Short access day 10 total infusions0.60.61.80.7-0.7-0.60.70.90.90.60.6-0.5-0.9-0.90.3-1.3
Short access total infusions0.20.20.50.3-0.4-0.30.40.30.60.40.4-0.4-0.5-0.50.3-0.7
Short access day 1 locomotion0.60.71.8-0.80.70.7-0.7-0.1-0.6-1.0-1.01.10.80.6-1.3-0.6
Short access day 10 total locomotion0.20.21.00.3-0.2-0.30.20.9-0.0-0.1-0.20.20.0-0.2-0.6-1.0
Short access total locomotion0.30.31.0-0.40.30.2-0.30.3-0.3-0.5-0.60.60.30.3-0.9-1.0
One hour access (0.3 mA shock)0.70.82.10.5-0.8-0.70.80.10.91.11.1-1.2-1.0-0.71.50.6
Compulsive drug intake0.20.21.1-0.30.20.1-0.2-0.7-0.30.10.1-0.20.10.40.41.0
One hour access (shock baseline)0.80.91.30.9-1.0-0.91.01.01.20.90.9-0.9-1.1-1.10.8-0.6
Social response proportion1.82.04.5-1.61.51.7-1.5-2.1-1.5-1.1-1.11.01.41.5-0.50.7
Social responses0.20.20.70.20.00.2-0.0-0.7-0.30.30.4-0.4-0.20.20.80.9
Social time0.00.00.1-0.40.1-0.1-0.1-0.3-0.40.10.1-0.10.10.00.20.2
Soleus weight1.33.86.42.2-2.1-2.22.02.52.31.71.7-1.6-1.9-1.71.1-2.1
Bone: stiffness0.30.50.80.6-0.8-0.90.80.80.70.80.8-0.7-0.6-0.40.6-0.2
Tibialis anterior weight6.722.927.25.2-4.9-4.85.03.95.05.15.2-5.2-5.1-4.95.2-0.6
Time to tail flick, vehicle, before self-admin0.20.20.8-0.30.20.1-0.20.2-0.3-0.4-0.40.50.40.2-0.7-0.9
Time to tail flick, vehicle, after self-admin0.10.10.40.4-0.2-0.30.20.40.20.10.1-0.1-0.2-0.3-0.0-0.6
Time to tail flick, test, before self-admin1.81.82.21.2-1.4-1.51.41.11.41.41.4-1.4-1.3-1.21.50.9
Time to tail flick, test, after self-admin0.20.20.40.6-0.5-0.50.50.60.40.40.4-0.4-0.4-0.40.3-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.20.5-0.3-0.20.30.20.40.40.4-0.4-0.4-0.30.40.0
Delta time to tail flick, test, before/after SA1.21.11.6-0.81.01.0-1.0-0.6-1.1-1.1-1.11.21.11.0-1.3-1.1
Tibia length1.23.54.22.0-2.0-2.02.01.92.01.91.9-1.9-1.8-1.71.7-1.1
Ambulatory time before self-admin0.20.21.3-0.3-0.1-0.00.1-0.4-0.00.30.3-0.3-0.1-0.00.61.1
Ambulatory time after self-admin0.10.10.5-0.0-0.0-0.10.0-0.3-0.00.10.2-0.2-0.00.20.40.7
Bone: tissue strength0.80.81.3-1.10.90.9-0.9-0.9-0.9-0.8-0.80.81.01.1-0.70.7
Total heroin consumption0.10.10.5-0.2-0.2-0.50.20.70.1-0.0-0.10.10.1-0.1-0.4-0.5
Bone: trabecular number0.20.42.40.6-0.4-0.50.40.80.50.10.1-0.0-0.2-0.6-0.2-1.5
Bone: trabecular spacing1.11.43.40.8-1.0-0.91.00.10.91.41.4-1.4-1.2-1.11.81.4
Bone: trabecular thickness0.20.31.00.00.0-0.2-0.00.9-0.0-0.4-0.40.50.60.4-1.0-0.7
Bone: trabecular tissue density4.15.811.7-2.12.42.5-2.4-3.1-2.6-1.9-1.91.82.22.9-1.23.4
Water consumed over 24 hours1.62.03.21.7-1.5-1.61.51.81.41.31.3-1.3-1.5-1.20.90.2
Number of responses in last shaping day0.20.20.40.3-0.3-0.30.30.00.20.50.5-0.5-0.4-0.10.60.6