Hub : Genes

Patj

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA XM_039109187.1 0.04 0.04 9.1e-05 0.02 0.02 0.02 0.02 2.2e-03 2.7e-03 3.0e-03 3.9e-03
2 Eye gene expression Patj 0.42 0.33 2.5e-03 0.12 0.1 0.12 0.11 7.3e-03 1.3e-02 7.2e-03 9.1e-03
3 NAcc isoform ratio XM_008763916.3 0.05 0.04 1.2e-06 0.04 0.04 0.05 0.04 8.8e-06 5.7e-06 3.6e-06 1.1e-05
4 OFC gene expression Patj 0.22 0.17 1.2e-03 0.07 0.06 0.07 0.06 8.6e-03 1.4e-02 7.7e-03 1.3e-02
5 Brain intron excision ratio chr5_113282422_113299279 0.2 0.16 1.1e-08 0.09 0.08 0.09 0.09 1.2e-08 1.2e-07 1.4e-08 1.8e-08
6 Adipose gene expression Patj 0.17 0.1 0.0e+00 0.12 0.12 0.12 0.12 2.1e-13 5.4e-13 3.5e-13 2.9e-13
7 Liver gene expression Patj 0.22 0.16 1.6e-12 0.08 0.07 0.08 0.08 4.5e-09 1.1e-08 4.8e-09 4.3e-09
8 Adipose alternative TSS NM_080398.1 0.03 0.03 1.9e-03 0.01 0.01 0 0.01 8.4e-03 7.8e-03 1.1e-01 9.5e-03
9 Brain intron excision ratio chr5_113208549_113235070 0.04 0.04 4.0e-04 0.03 0.02 0.02 0.02 2.0e-03 4.2e-03 3.2e-03 5.3e-03
10 PL gene expression Patj 0.05 0.04 4.9e-06 0.04 0.05 0.05 0.04 9.7e-06 3.8e-06 8.4e-06 8.7e-06
11 Adipose isoform ratio XM_008763915.3 0.05 0.04 2.9e-05 0.02 0.02 0.02 0.02 1.3e-03 1.2e-03 1.5e-03 1.8e-03
12 BLA gene expression Patj 0.05 0.05 5.4e-03 0.03 0.03 0.03 0.02 1.3e-02 1.3e-02 9.7e-03 1.8e-02
13 NAcc alternative TSS XM_008763916.3 0.03 0.03 8.1e-04 0.02 0.02 0.02 0.02 1.6e-03 2.7e-03 1.4e-03 3.0e-03
14 NAcc intron excision ratio chr5_113208549_113235070 0.02 0.02 6.3e-03 0.02 0.01 0.02 0.01 3.1e-03 6.0e-03 5.0e-03 5.8e-03
15 NAcc gene expression Patj 0.27 0.24 0.0e+00 0.2 0.2 0.2 0.2 5.8e-23 9.1e-23 3.7e-22 1.1e-22
16 NAcc mRNA stability Patj 0.12 0.11 8.3e-09 0.08 0.07 0.08 0.08 1.7e-09 5.2e-09 2.8e-09 3.7e-09
17 Brain gene expression Patj 0.33 0.16 0.0e+00 0.34 0.32 0.33 0.33 5.0e-32 6.6e-31 2.3e-31 2.4e-31
18 Brain mRNA stability Patj 0.18 0.11 0.0e+00 0.19 0.2 0.2 0.2 7.9e-18 1.0e-18 2.1e-18 2.7e-18
19 Adipose alternative polyA XM_008763915.3 0.06 0.04 3.3e-06 0.03 0.03 0.03 0.03 1.4e-04 1.4e-04 2.3e-04 1.7e-04
20 NAcc intron excision ratio chr5_113199348_113235070 0.03 0.03 5.4e-04 0.03 0.02 0.02 0.02 5.3e-04 1.3e-03 7.9e-04 1.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.10.20.40.40.6-0.60.5-0.30.4-0.5-0.5-0.6-0.50.50.5-0.6-0.5-0.5-0.50.50.5-0.50.5
Area under the delay curve0.90.91.51.21.2-1.01.1-1.21.1-0.8-1.0-1.2-0.90.91.1-1.1-0.8-0.7-0.70.70.8-0.80.8
BMI with tail0.10.30.8-0.6-0.80.6-0.60.5-0.50.60.50.90.5-0.5-0.70.50.30.50.5-0.6-0.50.4-0.3
BMI without tail0.30.50.8-0.7-0.80.6-0.70.7-0.70.70.70.90.7-0.7-0.80.40.70.70.7-0.8-0.70.8-0.8
Body weight0.10.30.50.60.4-0.50.6-0.60.7-0.7-0.6-0.4-0.50.50.5-0.4-0.5-0.5-0.50.40.5-0.40.5
Weight adjusted by age2.32.63.0-1.7-1.61.6-1.71.6-1.71.71.71.61.7-1.7-1.61.71.51.51.5-1.5-1.61.5-1.5
Bone surface2.03.54.0-1.8-1.81.7-1.91.8-1.71.91.91.81.9-1.9-2.01.51.92.02.0-2.0-1.92.0-1.9
Bone volume0.61.01.1-1.0-0.90.9-1.01.0-0.91.01.00.91.0-1.0-1.00.81.01.11.1-1.1-1.01.0-1.0
Breakpoint value in progressive ratio session0.80.92.61.61.3-0.81.3-1.41.5-0.6-1.0-1.2-0.90.91.1-1.0-0.3-0.3-0.30.50.6-0.40.3
Number of licking bursts0.00.00.10.20.3-0.20.0-0.20.20.20.1-0.00.1-0.1-0.2-0.30.30.30.3-0.3-0.20.3-0.3
Context. condit. distance diff. score2.83.33.91.62.0-1.91.8-1.61.7-1.9-1.8-1.9-1.81.81.9-1.7-1.9-1.9-1.91.81.8-1.81.9
Locomotion velocity, session 10.10.10.5-0.3-0.30.6-0.20.1-0.20.30.30.20.3-0.3-0.20.70.30.30.3-0.3-0.30.3-0.3
Locomotion distance, session 10.70.91.11.10.9-0.81.0-1.11.1-1.0-1.0-0.8-1.01.01.0-0.8-0.9-0.9-0.90.90.9-0.90.9
Locomotion velocity, session 20.30.40.7-0.7-0.70.6-0.60.5-0.60.60.60.80.6-0.6-0.70.70.60.60.6-0.6-0.60.6-0.6
Locomotion distance, session 20.10.10.2-0.1-0.40.5-0.20.1-0.10.30.30.40.3-0.3-0.30.30.40.50.5-0.5-0.40.5-0.4
Locomotion velocity, session 30.00.00.10.0-0.30.20.0-0.10.10.0-0.00.2-0.00.0-0.00.1-0.0-0.0-0.00.10.0-0.10.0
Locomotion distance, session 30.00.00.0-0.1-0.10.00.00.1-0.0-0.0-0.00.0-0.00.00.00.0-0.0-0.0-0.00.10.0-0.10.0
Stereotopy head waving bouts, day 30.60.71.31.00.9-0.90.9-1.01.1-0.7-0.8-0.8-0.80.80.7-1.1-0.6-0.7-0.70.60.7-0.60.6
Stereotopy head waving duration, day 30.70.91.11.00.8-0.81.0-1.01.0-0.9-0.9-0.9-0.90.91.0-0.8-0.9-0.9-0.90.90.9-0.90.9
Locomotion velocity, session 70.40.50.90.90.6-0.60.8-0.91.0-0.6-0.7-0.5-0.70.70.7-0.7-0.6-0.6-0.60.60.6-0.60.6
Locomotion distance, session 70.20.30.40.40.4-0.40.5-0.40.5-0.6-0.6-0.5-0.60.60.6-0.3-0.6-0.6-0.60.60.6-0.60.6
Stereotopy head waving bouts, day 71.01.21.5-1.0-1.00.9-1.01.0-0.91.11.11.11.1-1.1-1.10.71.21.21.2-1.2-1.11.2-1.2
Stereotopy head waving duration, day 70.91.11.4-0.8-0.90.8-1.00.8-0.81.11.11.11.1-1.1-1.10.51.21.21.2-1.2-1.11.2-1.2
Locomotion velocity, session 80.40.50.60.60.4-0.50.7-0.60.8-0.7-0.7-0.4-0.70.70.7-0.6-0.8-0.8-0.80.80.7-0.80.8
Locomotion distance, session 80.91.31.51.01.2-1.11.2-1.11.1-1.2-1.1-1.1-1.11.11.2-1.0-1.1-1.1-1.11.11.1-1.11.1
Degree of sensitization distance0.10.10.2-0.3-0.30.4-0.30.2-0.30.30.30.30.3-0.3-0.20.40.30.30.3-0.3-0.30.3-0.3
Degree of sensitization stereotypy1.21.31.6-1.2-1.10.9-1.21.2-1.11.21.21.31.2-1.2-1.20.71.21.21.2-1.2-1.21.2-1.2
Conditioned locomotion0.00.00.10.2-0.20.20.1-0.20.1-0.2-0.20.0-0.20.20.20.2-0.2-0.1-0.10.10.2-0.10.2
Cocaine response after cond. corrected0.70.71.0-0.7-0.80.8-0.80.6-0.70.90.90.70.9-0.9-1.00.61.00.90.9-1.0-0.91.0-1.0
Cocaine response after cond. not corrected0.50.60.8-0.5-0.70.7-0.70.4-0.50.80.80.60.8-0.8-0.90.50.90.80.8-0.9-0.80.9-0.9
Cocaine response before conditioning0.00.00.00.10.1-0.10.0-0.20.10.0-0.0-0.0-0.10.00.0-0.1-0.0-0.1-0.10.10.0-0.10.0
Saline control response0.10.10.3-0.10.20.00.20.1-0.1-0.5-0.3-0.4-0.30.30.50.4-0.5-0.4-0.40.40.5-0.50.5
Bone: connectivity density1.82.83.1-1.7-1.71.6-1.71.8-1.71.71.71.71.7-1.7-1.71.41.61.71.7-1.7-1.71.7-1.6
Bone: cortical apparent density7.910.411.23.23.3-3.43.2-3.13.1-3.2-3.2-3.3-3.23.23.2-3.3-3.2-3.3-3.33.33.2-3.23.2
Bone: cortical area0.10.20.3-0.5-0.30.4-0.40.5-0.50.30.40.20.4-0.4-0.30.50.40.40.4-0.4-0.40.5-0.4
Bone: cortical porosity0.40.50.6-0.7-0.70.8-0.70.6-0.70.60.70.60.7-0.7-0.60.80.70.70.7-0.7-0.70.7-0.7
Bone: cortical porosity0.60.70.9-0.9-0.80.9-0.80.8-0.90.70.80.70.8-0.8-0.70.90.90.90.9-0.9-0.80.9-0.9
Bone: cortical thickness0.30.40.70.50.8-0.70.7-0.50.5-0.7-0.6-0.8-0.60.60.8-0.5-0.7-0.7-0.70.70.7-0.60.7
Bone: cortical thickness0.00.00.2-0.2-0.10.3-0.10.2-0.30.00.10.10.1-0.10.00.40.00.00.0-0.0-0.00.0-0.0
Bone: cortical tissue density7.710.111.03.23.2-3.33.2-3.03.0-3.2-3.2-3.3-3.23.23.2-3.2-3.2-3.2-3.23.23.2-3.23.2
Condit. Reinf. active minus inactive responses0.00.00.10.1-0.10.30.0-0.10.00.0-0.0-0.00.0-0.00.10.20.10.10.1-0.0-0.00.0-0.1
Condit. Reinf. active-inactive response ratio0.10.10.20.30.00.10.3-0.30.2-0.3-0.3-0.3-0.30.30.40.1-0.4-0.4-0.40.40.4-0.40.4
Condit. Reinf. active responses0.20.30.6-0.3-0.50.7-0.40.4-0.40.40.50.50.5-0.5-0.30.70.60.60.6-0.5-0.50.5-0.6
Condit. Reinf. inactive responses0.20.30.5-0.5-0.40.5-0.40.7-0.50.40.50.50.5-0.5-0.40.70.60.60.6-0.5-0.50.5-0.6
Incentive salience index mean0.00.00.10.0-0.20.4-0.00.0-0.00.10.10.10.1-0.10.00.40.10.10.1-0.1-0.10.1-0.1
Condit. Reinf. lever presses0.20.20.50.50.5-0.30.6-0.40.5-0.6-0.5-0.6-0.50.50.7-0.3-0.5-0.4-0.40.50.5-0.50.5
Condit. Reinf. active minus inactive responses1.11.41.80.91.1-1.01.1-1.00.8-1.3-1.2-1.1-1.21.21.2-0.7-1.3-1.3-1.31.41.3-1.31.3
Condit. Reinf. active-inactive response ratio0.30.30.60.20.3-0.30.5-0.30.2-0.7-0.6-0.4-0.60.60.7-0.0-0.7-0.8-0.80.80.7-0.70.7
Condit. Reinf. active responses0.91.31.71.01.1-1.01.0-1.20.9-1.2-1.2-1.1-1.21.21.1-0.7-1.3-1.2-1.21.31.2-1.31.3
Condit. Reinf. inactive responses1.92.43.11.71.7-1.61.5-1.81.6-1.5-1.6-1.5-1.61.61.4-1.5-1.5-1.4-1.41.51.5-1.51.5
Condit. Reinf. lever presses2.93.94.9-1.9-2.22.1-2.01.8-2.02.02.02.11.9-1.9-2.12.01.92.02.0-1.9-1.91.9-1.9
Condit. Reinf. lever reinforcers received0.30.50.70.60.6-0.50.6-0.80.5-0.7-0.7-0.6-0.70.70.6-0.3-0.8-0.8-0.80.90.8-0.80.8
Conditioned reinforcement - actives0.40.40.70.90.7-0.60.7-0.80.7-0.8-0.6-0.7-0.60.60.7-0.6-0.6-0.5-0.50.50.6-0.50.5
Conditioned reinforcement - inactives1.31.42.11.41.4-1.01.4-1.41.3-1.4-1.2-1.4-1.11.11.4-0.9-1.4-0.8-0.80.81.1-0.81.3
Conditioned locomotion0.20.30.60.60.4-0.50.6-0.50.5-0.8-0.6-0.5-0.60.60.5-0.5-0.6-0.3-0.30.50.6-0.50.5
Patch foraging indifference point 0 sec5.99.611.5-3.0-2.93.4-3.03.2-3.13.13.12.73.1-3.1-2.83.32.93.43.4-3.3-3.13.1-2.9
Patch foraging indifference point AUC0.80.91.5-0.6-0.91.2-0.70.7-0.70.90.80.70.9-0.9-0.61.21.21.01.0-1.0-0.91.1-1.2
Delay disc. indifference point, 0s delay2.52.83.11.51.7-1.81.6-1.51.6-1.6-1.6-1.7-1.61.61.7-1.7-1.7-1.7-1.71.71.7-1.71.8
Delay disc. indifference point, 16s delay0.30.30.6-0.2-0.30.6-0.30.2-0.30.70.50.30.5-0.5-0.30.50.70.80.8-0.7-0.60.7-0.7
Delay disc. indifference point, 2s delay0.50.61.10.91.0-0.90.8-0.90.8-0.4-0.7-1.0-0.70.70.8-1.0-0.5-0.6-0.60.60.6-0.60.5
Delay disc. indifference point, 24s delay0.20.20.30.60.4-0.30.5-0.60.5-0.5-0.5-0.4-0.50.50.5-0.4-0.3-0.4-0.40.40.5-0.40.4
Delay disc. indifference point, 4s delay3.84.05.32.12.2-1.82.1-2.12.1-2.0-2.1-2.2-2.12.12.3-1.8-2.0-1.8-1.81.82.0-1.91.9
Delay disc. indifference point, 8s delay2.42.53.31.71.8-1.71.7-1.71.7-1.5-1.6-1.8-1.61.61.6-1.8-1.5-1.4-1.41.41.5-1.41.5
Indifference point function ln k0.10.20.30.30.5-0.50.3-0.30.3-0.4-0.4-0.5-0.40.40.4-0.5-0.4-0.4-0.40.40.4-0.50.4
Indifference point function log k0.10.20.30.30.5-0.50.3-0.30.3-0.4-0.4-0.5-0.40.40.4-0.5-0.4-0.4-0.40.40.4-0.50.4
Patch foraging total patch changes 0 sec5.48.611.0-2.9-2.73.3-2.83.0-2.92.92.92.52.9-2.9-2.53.32.73.33.3-3.2-2.93.0-2.8
Patch foraging total patch changes 12 sec0.70.91.5-0.7-0.71.1-0.70.9-0.71.00.90.60.9-0.9-0.71.11.01.21.2-1.1-0.91.0-1.0
Patch foraging total patch changes 18 sec1.92.45.1-1.3-1.62.2-1.31.5-1.41.41.41.21.4-1.4-1.02.31.41.81.8-1.6-1.41.5-1.4
Patch foraging total patch changes 24 sec1.51.93.1-1.1-1.31.8-1.11.1-1.11.51.31.01.3-1.3-1.01.71.41.71.7-1.6-1.41.5-1.4
Patch foraging total patch changes 6 sec1.92.84.7-1.5-1.62.1-1.51.7-1.61.71.61.31.6-1.6-1.22.21.51.81.8-1.8-1.61.8-1.6
Patch foraging time to switch 0 sec2.13.34.01.92.0-2.01.8-1.71.9-1.6-1.7-1.9-1.71.71.7-2.0-1.9-1.8-1.81.71.7-1.61.9
Patch foraging water rate 0 sec1.72.73.5-1.6-1.51.6-1.61.5-1.51.51.61.61.7-1.7-1.51.71.81.81.8-1.8-1.71.7-1.9
Patch foraging water rate 12 sec3.45.26.3-2.3-2.12.2-2.22.3-2.32.12.32.22.3-2.3-2.22.12.32.52.5-2.3-2.22.3-2.3
Patch foraging water rate 18 sec0.10.20.4-0.6-0.30.2-0.40.4-0.40.30.40.40.5-0.5-0.30.30.60.40.4-0.5-0.40.4-0.6
Patch foraging water rate 24 sec0.00.00.10.00.2-0.20.1-0.20.1-0.10.0-0.10.1-0.10.0-0.30.30.30.3-0.3-0.10.2-0.3
Patch foraging water rate 6 sec0.30.40.7-0.6-0.70.7-0.60.6-0.50.50.60.80.6-0.6-0.60.60.60.70.7-0.6-0.60.6-0.7
Seeking ratio, delayed vs. immediate footshock0.10.10.20.30.10.20.3-0.50.2-0.4-0.2-0.2-0.20.20.20.30.30.20.2-0.10.10.1-0.3
Distance traveled before self-admin0.20.20.50.50.7-0.30.7-0.30.60.1-0.3-0.7-0.20.20.7-0.40.2-0.0-0.0-0.20.10.3-0.2
Distance traveled after self-admin0.30.30.90.40.30.30.4-0.20.40.40.2-0.40.3-0.30.20.10.90.80.8-0.9-0.51.0-0.9
Extensor digitorum longus weight0.62.42.71.51.4-1.31.5-1.61.6-1.6-1.6-1.5-1.61.61.5-1.3-1.6-1.6-1.61.61.6-1.61.6
Bone: elastic displacement0.60.71.10.70.7-0.60.8-0.70.6-0.9-0.9-0.9-0.90.90.9-0.5-0.9-1.0-1.01.00.9-1.00.9
Bone: elastic work1.11.41.81.01.1-1.01.2-1.11.0-1.3-1.2-1.3-1.21.21.3-1.0-1.2-1.2-1.21.21.3-1.31.2
Bone: endosteal estimation0.61.31.5-1.0-1.21.2-1.11.1-1.01.21.11.11.2-1.2-1.11.11.11.21.2-1.2-1.21.2-1.1
Bone: endosteal perimeter1.22.63.0-1.5-1.51.6-1.61.5-1.51.61.61.41.6-1.6-1.61.51.61.71.7-1.7-1.71.7-1.6
Epididymis fat weight2.25.26.82.62.0-2.02.3-2.52.4-2.4-2.4-2.1-2.42.42.2-1.9-2.2-2.4-2.42.32.3-2.22.2
Delta time in closed arm before/after self-admin0.30.20.5-0.7-0.60.5-0.50.6-0.70.60.50.50.5-0.5-0.50.40.60.20.2-0.1-0.40.1-0.6
Delta time in open arm before/after self-admin1.11.11.7-1.0-0.91.1-1.00.8-0.90.71.01.01.0-1.0-1.01.10.81.31.3-1.3-1.01.2-0.8
Diff in mean of infusions in LGA sessions0.40.51.00.90.8-0.51.0-1.00.9-0.6-0.7-1.0-0.60.71.0-0.5-0.4-0.5-0.50.50.5-0.50.4
Delay discount exponential model param0.90.91.5-1.2-1.21.0-1.11.2-1.10.81.01.21.0-1.0-1.11.00.80.70.7-0.7-0.90.8-0.8
Extinction: sum of active levers before priming0.50.51.20.81.1-0.91.0-0.81.0-0.5-0.7-0.8-0.60.60.8-1.0-0.5-0.3-0.30.50.5-0.50.5
Active lever presses in extinction session 60.10.10.30.50.5-0.20.6-0.30.4-0.2-0.3-0.6-0.30.30.6-0.3-0.4-0.1-0.10.10.2-0.10.5
Bone: final force0.40.61.20.80.9-1.00.8-0.80.9-0.8-0.8-0.9-0.80.80.7-1.1-0.7-0.7-0.70.70.8-0.70.7
Bone: final moment0.00.00.10.10.2-0.30.1-0.10.1-0.1-0.1-0.2-0.10.10.1-0.3-0.1-0.0-0.00.00.1-0.10.1
Food consumed during 24 hour testing period0.50.61.81.01.0-1.10.8-1.11.0-0.5-0.7-0.9-0.70.70.4-1.3-0.6-0.5-0.50.50.6-0.50.6
Glucose0.20.31.4-0.9-0.60.8-0.50.8-0.90.20.40.50.4-0.4-0.21.20.10.20.2-0.1-0.20.1-0.1
Heart weight2.73.84.91.71.8-1.91.9-1.61.7-2.1-1.9-1.9-1.91.92.0-1.8-2.1-2.2-2.22.22.0-2.12.1
Delay discount hyperbolic model param1.11.11.8-1.3-1.31.0-1.21.3-1.20.91.11.31.1-1.0-1.21.10.90.80.8-0.8-1.00.9-0.8
Intermittent access intake day 1-15 change0.80.81.81.20.9-0.71.0-1.31.0-0.9-0.9-0.9-0.90.91.0-0.8-0.8-0.8-0.80.70.8-0.60.7
Intermittent access intake escalation0.80.81.91.21.0-0.81.0-1.41.0-0.7-0.9-0.9-0.90.90.9-0.9-0.7-0.7-0.70.60.7-0.60.6
Intermittent access intake escalation 20.70.71.41.10.9-0.90.9-1.20.9-0.7-0.8-0.8-0.80.80.8-0.9-0.6-0.8-0.80.70.7-0.60.5
Intermitt. access day 1 inactive lever presses1.51.62.5-1.6-1.31.3-1.41.5-1.41.11.31.21.2-1.3-1.21.30.81.21.2-1.3-1.21.3-0.8
Intermitt. access day 15 inactive lever presses0.91.02.30.80.9-0.61.0-0.80.8-1.2-1.1-1.0-1.11.11.1-0.3-1.5-0.7-0.70.81.1-0.91.4
Intermitt. access escalation Index1.81.62.6-1.4-1.61.1-1.51.4-1.31.51.31.61.2-1.2-1.60.91.20.90.9-0.8-1.10.9-1.2
Intermittent access day 1 total infusions0.10.20.80.30.3-0.20.3-0.20.2-0.7-0.4-0.4-0.40.40.4-0.1-0.9-0.2-0.20.20.5-0.20.7
Intermittent access day 15 total infusions0.50.51.20.90.7-0.60.7-0.90.6-0.8-0.8-0.6-0.80.80.6-0.7-1.1-0.6-0.60.60.8-0.50.9
Intermittent access terminal intake (last 3 days)0.20.20.40.70.5-0.30.4-0.60.4-0.6-0.4-0.4-0.40.40.4-0.3-0.6-0.2-0.20.20.4-0.10.5
Intermittent access total infusions0.30.30.90.60.5-0.40.4-0.50.3-0.7-0.6-0.4-0.60.60.5-0.4-0.9-0.4-0.40.40.6-0.40.8
Intermittent access day 1 locomotion0.20.30.5-0.6-0.70.6-0.60.7-0.70.10.40.70.3-0.4-0.50.6-0.10.50.5-0.4-0.30.40.1
Intermittent access day 15 total locomotion0.00.00.1-0.1-0.30.2-0.20.1-0.2-0.10.10.30.1-0.1-0.30.1-0.20.30.3-0.2-0.10.20.2
Intermittent access total locomotion0.20.20.3-0.4-0.50.4-0.50.5-0.50.10.40.60.4-0.4-0.50.40.20.50.5-0.5-0.40.5-0.3
Intermittent access standard deviation1.01.01.31.01.0-1.11.0-1.01.0-0.9-1.0-0.9-1.01.00.9-1.2-1.0-1.1-1.11.01.0-1.01.0
Left kidney weight0.41.22.11.31.1-1.21.1-1.51.3-1.1-1.1-1.0-1.11.10.9-1.3-0.9-1.0-1.01.01.0-0.90.9
Right kidney weight0.30.92.01.21.1-1.11.0-1.41.2-0.9-0.9-1.1-0.90.90.8-1.2-0.5-0.9-0.90.80.8-0.70.5
Cocaine induced anxiety0.10.10.2-0.10.0-0.20.10.10.1-0.3-0.2-0.1-0.20.20.0-0.3-0.5-0.3-0.30.30.3-0.30.5
Post-drug Anxiety1.01.11.71.01.0-1.11.0-1.01.1-1.0-1.0-0.9-1.11.00.9-1.3-1.2-1.1-1.11.11.1-1.01.2
Baseline Anxiety0.40.50.70.80.6-0.80.6-0.80.6-0.4-0.6-0.5-0.60.60.5-0.8-0.6-0.9-0.90.90.6-0.80.6
Tail length0.72.03.01.71.7-1.61.7-1.71.6-1.6-1.4-1.7-1.31.41.6-1.6-0.9-1.1-1.11.11.2-1.00.9
Length with tail0.51.82.81.61.5-1.21.5-1.51.5-1.7-1.4-1.6-1.41.41.6-1.1-1.1-1.2-1.21.11.3-1.11.1
Length without tail0.10.10.30.30.3-0.10.4-0.40.4-0.6-0.4-0.4-0.40.40.40.1-0.4-0.3-0.30.30.4-0.30.4
Times rat made contact with spout0.00.00.1-0.10.2-0.3-0.1-0.0-0.20.10.10.00.1-0.1-0.3-0.3-0.00.10.1-0.0-0.10.00.0
Lifetime Intake0.10.10.50.30.2-0.20.2-0.20.1-0.6-0.3-0.1-0.30.30.2-0.1-0.7-0.1-0.10.20.4-0.20.5
Liver weight, left2.03.13.91.51.9-1.61.8-1.51.6-2.0-1.8-1.9-1.81.81.9-1.2-1.9-1.7-1.71.81.9-1.81.9
Liver weight, right6.210.311.13.33.2-3.03.3-3.33.2-3.2-3.3-3.2-3.33.33.3-2.7-3.2-3.3-3.33.23.3-3.23.3
Locomotor activity0.00.00.1-0.1-0.30.1-0.10.2-0.1-0.1-0.00.1-0.00.00.10.20.0-0.2-0.20.20.1-0.1-0.0
Locomotor testing distance1.42.32.6-1.4-1.61.6-1.51.4-1.51.51.51.61.5-1.5-1.51.61.51.51.5-1.5-1.51.5-1.6
Locomotor testing rearing0.00.00.10.30.30.00.2-0.30.2-0.1-0.2-0.4-0.20.20.30.2-0.1-0.0-0.00.10.2-0.20.1
Locomotion in novel chamber1.41.82.0-1.1-1.41.4-1.40.9-1.21.41.31.41.3-1.3-1.41.31.31.41.4-1.4-1.41.4-1.3
Locomotion in novel chamber post-restriction0.00.00.2-0.3-0.0-0.40.10.3-0.2-0.1-0.0-0.0-0.00.00.0-0.5-0.1-0.4-0.40.20.1-0.20.1
Fecal boli incidents, locomotor time 10.00.00.1-0.1-0.20.2-0.20.1-0.30.00.10.10.1-0.1-0.20.3-0.20.10.1-0.1-0.00.00.1
Change in fecal boli incidents, locomotor task0.20.20.30.30.4-0.60.4-0.40.4-0.5-0.4-0.3-0.40.40.3-0.6-0.2-0.5-0.50.50.4-0.30.2
Time >=10cm from walls, locomotor time 10.10.10.4-0.3-0.50.6-0.40.3-0.40.30.30.40.3-0.3-0.30.70.00.30.3-0.4-0.30.3-0.2
Bouts of movement, locomotor time 10.10.10.2-0.4-0.20.1-0.30.4-0.20.10.20.30.2-0.2-0.30.10.10.20.2-0.2-0.20.2-0.1
Total resting periods, locomotor time 10.10.10.2-0.4-0.30.1-0.30.4-0.20.10.30.30.2-0.2-0.40.10.20.20.2-0.3-0.20.3-0.2
Rest time, locomotor task time 10.00.00.2-0.20.2-0.1-0.00.10.00.00.1-0.10.1-0.1-0.1-0.10.30.40.4-0.4-0.10.5-0.3
Distance moved, locomotor task time 10.10.10.50.20.2-0.50.2-0.00.10.0-0.2-0.1-0.20.20.3-0.5-0.4-0.7-0.70.70.2-0.70.4
Vertical activity count, locomotor time 10.10.10.3-0.2-0.1-0.2-0.30.5-0.20.50.40.40.4-0.4-0.4-0.50.40.20.2-0.2-0.50.2-0.4
Time >=10cm from walls, locomotor time 22.42.63.71.61.5-1.71.4-1.51.4-1.4-1.6-1.4-1.61.61.4-1.7-1.9-1.6-1.61.61.6-1.81.8
Bouts of movement, locomotor time 20.60.71.5-1.2-0.90.6-0.91.1-1.00.70.90.80.9-0.9-0.90.60.80.70.7-0.7-0.80.7-0.6
Total resting periods, locomotor time 20.80.81.7-1.3-1.00.8-1.11.1-1.10.70.90.90.9-0.9-1.00.80.90.80.8-0.8-0.80.8-0.7
Rest time, locomotor task time 20.91.02.0-1.0-0.91.2-0.80.8-0.80.80.90.90.9-0.9-0.81.21.21.21.2-1.2-0.91.4-1.2
Distance moved, locomotor task time 21.51.83.51.21.4-1.81.2-1.01.2-0.8-1.1-1.1-1.11.11.1-1.9-1.4-1.5-1.51.51.1-1.71.3
Vertical activity count, locomotor time 20.50.62.30.70.9-1.30.6-0.40.6-0.4-0.5-0.6-0.50.50.5-1.5-0.6-0.7-0.70.70.5-0.90.7
Light reinforcement 10.50.81.30.90.8-0.71.0-0.80.9-1.0-1.0-1.1-1.01.01.1-0.7-0.9-0.7-0.70.81.0-1.01.0
Light reinforcement 20.20.30.60.50.5-0.60.6-0.40.6-0.5-0.5-0.7-0.50.50.6-0.8-0.5-0.6-0.60.50.6-0.60.5
Bone: marrow area0.61.21.4-1.0-1.11.1-1.11.0-1.01.11.11.11.1-1.1-1.11.01.11.21.2-1.2-1.11.2-1.1
Bone: maximum diameter0.50.81.1-0.9-0.80.9-0.91.0-0.90.90.90.81.0-0.9-0.80.90.91.01.0-1.0-0.91.0-0.9
Bone: maximum force0.10.20.40.30.6-0.60.5-0.30.5-0.5-0.4-0.6-0.40.40.5-0.6-0.4-0.3-0.30.30.4-0.40.4
Bone: maximum moment0.10.10.2-0.4-0.20.2-0.20.4-0.30.20.30.20.3-0.3-0.30.20.30.40.4-0.4-0.30.3-0.3
Mean time between licks in bursts6.89.511.13.13.3-3.13.1-3.03.0-3.0-3.1-3.2-3.13.13.1-2.9-3.1-3.1-3.13.13.1-3.13.1
Mean num. licks in bursts0.00.10.2-0.5-0.30.2-0.30.4-0.40.00.10.30.1-0.1-0.20.3-0.2-0.1-0.10.20.0-0.20.2
Cd content in liver1.41.52.1-1.3-1.21.3-1.21.3-1.31.11.21.21.2-1.2-1.11.41.21.21.2-1.2-1.21.2-1.2
Co content in liver0.10.10.20.30.4-0.30.4-0.20.4-0.4-0.3-0.4-0.30.30.4-0.3-0.4-0.3-0.30.30.3-0.30.4
Cu content in liver0.30.40.50.70.5-0.60.7-0.70.6-0.6-0.7-0.6-0.70.70.6-0.7-0.7-0.6-0.60.60.6-0.60.7
Fe content in liver0.80.91.2-1.1-0.91.0-1.01.1-1.11.01.00.91.0-1.0-0.91.10.90.90.9-0.9-0.90.9-0.9
K content in liver0.90.91.61.01.0-1.11.0-1.01.1-0.9-0.9-1.0-0.90.90.9-1.3-0.9-0.8-0.80.80.9-0.80.9
Mg content in liver0.50.50.7-0.6-0.60.5-0.60.6-0.60.80.70.60.8-0.8-0.70.20.80.80.8-0.8-0.80.8-0.8
Mn content in liver0.10.10.10.30.3-0.30.2-0.30.4-0.2-0.2-0.3-0.20.20.2-0.3-0.2-0.1-0.10.10.2-0.20.2
Na content in liver3.33.53.91.91.8-1.81.9-2.01.9-1.8-1.9-1.8-1.91.91.8-1.8-1.8-1.9-1.91.91.9-1.91.8
Rb content in liver0.60.81.20.91.0-1.01.0-0.91.0-0.7-0.8-1.0-0.80.80.9-1.1-0.8-0.8-0.80.80.8-0.80.8
Se content in liver1.01.31.6-1.0-1.31.2-1.11.0-1.11.11.11.21.1-1.1-1.11.01.11.21.2-1.2-1.11.2-1.1
Sr content in liver0.10.00.1-0.2-0.10.2-0.20.2-0.20.20.20.10.2-0.2-0.10.20.20.20.2-0.2-0.20.2-0.2
Zn content in liver0.91.01.3-1.1-1.00.9-1.01.1-1.11.01.01.01.0-1.0-1.00.91.01.01.0-1.0-1.01.0-1.0
Bone: minimum diameter1.52.73.2-1.6-1.51.7-1.61.7-1.61.51.71.41.7-1.7-1.51.71.71.81.8-1.8-1.71.8-1.7
Time in familiar zone, hab. session 12.82.62.91.71.5-1.41.7-1.71.6-1.6-1.7-1.7-1.71.71.7-1.4-1.6-1.6-1.61.61.6-1.61.6
Time in novel zone, hab. session 17.37.17.9-2.6-2.62.5-2.72.6-2.62.72.72.82.7-2.7-2.82.42.72.72.7-2.7-2.72.7-2.7
Total zone transitions, hab. session 11.92.73.51.81.7-1.71.7-1.71.9-1.6-1.6-1.6-1.61.61.6-1.8-1.5-1.5-1.51.51.5-1.51.5
Total locomotion distance, hab. session 10.10.20.40.70.4-0.50.4-0.60.7-0.3-0.4-0.3-0.40.40.3-0.6-0.2-0.2-0.20.20.3-0.20.2
Locomotion velocity, hab. session 10.20.20.50.70.5-0.60.5-0.70.7-0.4-0.5-0.4-0.50.50.3-0.7-0.3-0.3-0.30.30.4-0.30.3
Time in familiar zone, hab. session 20.60.60.80.80.9-0.90.8-0.80.8-0.8-0.8-0.9-0.80.80.7-0.9-0.8-0.8-0.80.80.8-0.80.8
Time in novel zone, hab. session 21.31.31.8-1.1-1.21.3-1.11.0-1.11.11.11.21.1-1.1-1.11.41.11.11.1-1.1-1.11.1-1.1
Total zone transitions, hab. session 24.66.08.02.82.3-2.12.6-2.82.7-2.4-2.5-2.3-2.52.52.5-2.2-2.4-2.4-2.42.32.4-2.32.4
Total locomotion distance, hab. session 21.82.44.01.91.4-1.31.6-2.01.9-1.5-1.6-1.4-1.61.61.5-1.4-1.5-1.5-1.51.41.5-1.41.5
Locomotion velocity, hab. session 21.62.13.51.81.3-1.21.5-1.91.8-1.4-1.5-1.3-1.51.51.4-1.3-1.3-1.3-1.31.31.4-1.31.3
Novel to familiar place preference ratio1.31.32.0-1.2-1.01.2-1.31.1-1.41.21.21.11.1-1.2-1.11.41.11.11.1-1.1-1.11.1-1.1
Novelty place preference0.90.91.5-1.0-0.91.0-1.10.9-1.21.01.00.91.0-1.0-0.91.20.90.90.9-0.9-0.90.9-0.9
Time in novel zone, NPP test1.41.42.2-1.3-1.11.3-1.31.2-1.51.21.21.11.2-1.2-1.11.41.11.11.1-1.2-1.11.2-1.1
Total zone transitions, NPP test1.82.53.11.71.5-1.41.7-1.71.8-1.7-1.6-1.6-1.61.61.7-1.4-1.5-1.5-1.51.51.6-1.51.5
Total locomotion distance, NPP test0.10.20.50.70.4-0.30.5-0.70.7-0.4-0.5-0.5-0.50.50.5-0.3-0.3-0.3-0.30.30.4-0.30.3
Locomotion velocity, NPP test0.30.51.01.00.7-0.60.8-1.00.9-0.7-0.7-0.7-0.70.70.7-0.6-0.5-0.5-0.50.50.6-0.50.5
Intraocular pressure0.00.00.3-0.3-0.10.2-0.20.5-0.40.20.20.10.1-0.1-0.10.3-0.10.00.0-0.0-0.1-0.00.1
Delta distance traveled before/after self-admin0.70.81.4-0.5-0.81.0-0.70.7-0.50.60.80.60.8-0.8-0.71.01.01.11.1-1.2-0.91.1-1.0
Delta ambulatory time before/after self-admin0.30.40.9-0.3-0.50.6-0.40.4-0.20.40.50.40.6-0.6-0.50.50.70.80.8-1.0-0.60.9-0.7
Parametrial fat weight5.210.010.9-3.2-3.03.0-3.33.2-3.23.13.23.33.2-3.2-3.33.03.13.23.2-3.1-3.23.1-3.1
Pavlov. Cond. lever latency0.30.30.60.60.8-0.80.5-0.60.5-0.6-0.6-0.6-0.60.60.5-0.6-0.5-0.5-0.50.50.5-0.50.5
Pavlov. Cond. magazine entry latency0.60.81.00.80.6-0.60.9-0.80.8-0.9-0.9-0.9-0.90.91.0-0.6-1.0-0.9-0.90.90.9-0.91.0
Pavlov. Cond. change in total contacts0.40.40.7-0.7-0.80.8-0.60.7-0.70.60.60.70.6-0.6-0.50.80.50.60.6-0.6-0.60.6-0.5
Pavlov. Cond. index score0.00.00.1-0.1-0.30.30.10.1-0.0-0.1-0.10.1-0.10.10.20.2-0.1-0.1-0.10.10.1-0.10.1
Pavlov. Cond. latency score0.00.00.2-0.2-0.50.5-0.00.2-0.10.00.00.20.0-0.00.10.4-0.0-0.0-0.00.0-0.0-0.00.0
Pavlov. Cond. lever contacts0.00.00.1-0.1-0.20.20.10.10.00.10.00.10.0-0.00.10.1-0.0-0.0-0.00.0-0.0-0.00.0
Pavlov. Cond. magazine entry number0.70.91.3-0.9-0.50.5-1.00.8-0.91.01.00.91.0-1.0-1.10.51.11.01.0-1.0-1.01.0-1.1
Pavlov. Cond. intertrial magazine entries0.70.81.20.91.1-0.90.9-0.80.9-0.9-0.9-0.9-0.90.90.9-0.6-0.9-0.9-0.90.90.9-0.90.9
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.1-0.30.30.10.1-0.0-0.1-0.10.1-0.10.10.20.3-0.1-0.1-0.10.10.1-0.10.1
Pavlov. Cond. response bias0.30.40.50.60.4-0.40.7-0.50.6-0.6-0.6-0.6-0.60.60.7-0.5-0.7-0.6-0.60.70.6-0.70.7
Pavlov. Cond. lever latency1.21.62.21.41.5-1.31.4-1.41.5-1.2-1.3-1.3-1.31.31.3-1.4-1.1-1.1-1.11.11.2-1.11.1
Pavlov. Cond. magazine entry latency1.51.83.2-1.4-1.81.6-1.41.5-1.41.21.31.51.3-1.3-1.31.41.11.21.2-1.1-1.21.2-1.1
Pavlov. Cond. change in total contacts2.02.83.8-1.5-1.91.9-1.71.6-1.71.71.71.71.6-1.6-1.71.71.61.61.6-1.5-1.61.6-1.6
Pavlov. Cond. index score1.72.13.6-1.4-1.91.7-1.51.5-1.61.41.41.61.4-1.4-1.51.61.31.31.3-1.3-1.41.3-1.3
Pavlov. Cond. latency score1.41.73.1-1.3-1.81.6-1.31.3-1.41.21.31.41.2-1.2-1.31.41.11.21.2-1.1-1.21.2-1.1
Pavlov. Cond. lever contacts2.02.83.5-1.6-1.91.7-1.81.7-1.71.71.71.81.7-1.7-1.81.61.51.61.6-1.5-1.61.6-1.5
Pavlov. Cond. magazine entry number0.50.61.40.81.2-1.10.8-1.00.9-0.6-0.7-0.9-0.60.60.6-1.0-0.5-0.5-0.50.50.6-0.50.5
Pavlov. Cond. intertrial magazine entries1.21.52.01.21.3-1.11.2-1.41.2-1.3-1.3-1.3-1.31.31.3-0.9-1.2-1.2-1.21.31.3-1.31.2
Pavlov. Cond. lever-magazine prob. diff.1.62.03.3-1.4-1.81.7-1.51.5-1.51.41.41.51.4-1.4-1.41.51.21.31.3-1.2-1.31.3-1.2
Pavlov. Cond. response bias1.62.23.0-1.5-1.71.5-1.61.6-1.61.51.51.61.5-1.5-1.61.41.31.31.3-1.3-1.41.4-1.3
Time in closed arm before self-admin0.10.10.60.40.4-0.50.2-0.20.4-0.1-0.3-0.1-0.30.30.1-0.7-0.3-0.2-0.20.30.3-0.30.3
Time in closed arm after self-admin0.10.10.4-0.4-0.4-0.2-0.50.4-0.40.60.20.60.2-0.2-0.6-0.50.3-0.2-0.20.3-0.1-0.2-0.3
Time in open arm before self-admin0.10.10.40.20.00.50.2-0.20.1-0.10.2-0.30.2-0.20.30.60.60.40.4-0.6-0.30.6-0.6
Time in open arm after self-admin2.02.24.0-1.2-1.21.7-1.21.0-1.21.11.41.21.4-1.4-1.21.81.51.91.9-2.0-1.52.0-1.4
Bone: periosteal estimation0.61.31.5-1.0-1.11.2-1.11.1-1.11.11.11.01.1-1.1-1.01.11.11.21.2-1.2-1.11.2-1.1
Bone: periosteal perimeter0.50.81.0-0.9-0.80.9-0.91.0-0.90.80.90.70.9-0.9-0.80.90.91.01.0-1.0-0.91.0-0.9
Bone: post-yield work1.62.12.5-1.4-1.41.5-1.41.3-1.31.51.51.41.5-1.5-1.51.31.51.61.6-1.6-1.51.6-1.5
Progressive ratio test 1 active lever presses4.24.46.61.92.0-1.92.1-1.81.8-2.6-2.2-2.0-2.22.22.2-1.7-2.6-2.0-2.02.12.3-2.12.3
Progressive ratio test 1 breakpoint5.45.78.22.22.3-2.22.4-2.12.2-2.9-2.5-2.4-2.52.52.5-2.0-2.8-2.2-2.22.32.5-2.32.5
Progressive ratio test 1 inactive lever presses2.12.34.81.21.5-1.41.4-1.21.2-1.9-1.6-1.5-1.61.61.6-1.2-2.2-1.3-1.31.31.7-1.32.0
Progressive ratio test 2 active lever presses0.30.30.70.70.7-0.40.6-0.60.5-0.8-0.5-0.7-0.50.50.7-0.3-0.7-0.2-0.20.30.5-0.20.6
Progressive ratio test 2 breakpoint0.30.30.80.70.7-0.30.7-0.60.5-0.9-0.6-0.7-0.60.60.8-0.1-0.7-0.3-0.30.30.5-0.30.6
Progressive ratio test 2 inactive lever presses0.30.40.80.70.8-0.40.7-0.60.6-0.8-0.6-0.8-0.60.60.8-0.2-0.9-0.1-0.10.10.5-0.10.7
Incentive Sensitization - Responses0.20.20.4-0.3-0.30.6-0.40.3-0.40.60.50.30.5-0.5-0.30.70.40.60.6-0.6-0.60.6-0.4
Incentive Sensitization - Breakpoint0.30.30.6-0.3-0.40.6-0.40.3-0.40.70.60.40.6-0.6-0.40.70.60.70.7-0.7-0.70.8-0.6
Sum of active levers in priming session hrs 5-62.72.64.12.02.0-1.71.9-1.92.0-1.6-1.6-1.8-1.51.61.8-1.7-1.4-1.2-1.21.21.4-1.11.4
Progressive ratio0.20.30.60.70.7-0.60.6-0.80.6-0.5-0.5-0.6-0.50.50.6-0.5-0.4-0.5-0.50.40.4-0.40.4
Food seeking constrained by brief footshock4.04.95.82.22.1-2.22.1-2.22.1-2.1-2.2-2.1-2.22.22.1-2.1-2.3-2.4-2.42.42.2-2.42.3
Seeking ratio, punishment vs. effort0.70.91.30.80.7-0.80.8-0.70.9-0.9-0.9-0.8-1.01.00.8-0.8-1.1-1.1-1.11.11.0-1.11.1
Retroperitoneal fat weight0.20.81.21.00.8-0.80.9-1.11.0-1.0-0.9-0.7-0.90.90.9-0.8-0.8-1.0-1.01.00.9-0.90.8
Reaction time number correct0.00.00.1-0.10.10.10.1-0.10.1-0.30.0-0.10.1-0.10.20.20.20.20.2-0.2-0.10.2-0.3
Reaction time mean minus median0.20.20.4-0.2-0.20.4-0.30.1-0.20.70.50.40.5-0.5-0.50.40.70.60.6-0.6-0.60.6-0.6
Reaction time mean minus median AUC0.00.00.10.20.20.10.1-0.30.20.30.0-0.00.0-0.0-0.00.10.20.30.3-0.2-0.10.1-0.2
Reaction time num false alarms0.30.41.0-0.5-0.81.0-0.60.4-0.60.50.50.60.5-0.5-0.60.90.40.70.7-0.8-0.50.6-0.5
Reaction time num false alarms AUC0.81.12.0-1.0-1.21.4-1.00.9-1.00.80.91.00.9-0.9-0.91.40.81.11.1-1.2-0.90.9-0.8
Reaction time trials correct on left0.00.00.1-0.10.10.10.1-0.10.1-0.30.0-0.10.1-0.10.20.20.20.20.2-0.2-0.10.2-0.3
Reaction time trials on left0.00.00.1-0.20.00.10.0-0.0-0.0-0.30.10.00.1-0.10.10.30.30.30.3-0.3-0.10.3-0.3
Reaction time mean0.70.91.4-0.9-1.00.9-1.10.9-1.01.11.01.11.0-1.0-1.20.90.90.80.8-0.8-1.00.9-0.9
Reaction time mean AUC0.30.40.6-0.5-0.60.6-0.70.5-0.60.70.60.70.6-0.6-0.80.60.60.50.5-0.5-0.60.6-0.5
Median of all reaction times0.81.11.7-1.0-1.21.0-1.21.1-1.11.21.11.31.1-1.1-1.30.90.90.90.9-0.8-1.10.9-0.9
Reaction time omissions0.91.22.4-1.5-1.21.3-1.21.3-1.41.01.01.11.0-1.0-1.01.60.90.80.8-0.7-0.90.6-0.9
Reaction time false alarm rate0.91.32.1-1.0-1.41.5-1.21.1-1.11.11.01.11.0-1.0-1.11.40.81.11.1-1.2-1.01.0-0.8
Reaction time premature initiation rate0.40.61.00.70.8-0.80.8-0.60.8-0.8-0.8-0.7-0.80.80.8-1.0-0.8-0.6-0.60.70.9-0.80.8
Reaction time premature initiations0.60.81.30.81.0-0.91.0-0.81.0-1.1-1.0-0.9-1.00.91.0-0.9-0.8-0.6-0.60.70.9-0.80.8
Std. dev. reaction times1.42.02.8-1.2-1.21.4-1.31.1-1.21.71.51.41.5-1.5-1.51.41.61.51.5-1.4-1.51.5-1.5
Reaction time trials completed0.00.00.1-0.20.00.10.0-0.0-0.0-0.30.10.00.1-0.10.10.30.30.30.3-0.3-0.10.3-0.3
Reaction time trials AUC0.00.00.1-0.20.00.20.0-0.0-0.0-0.30.10.00.1-0.10.10.40.30.30.3-0.3-0.20.3-0.3
Run reversals in cocaine runway, females0.00.00.10.00.0-0.2-0.00.3-0.1-0.0-0.00.1-0.00.0-0.0-0.20.0-0.2-0.20.20.0-0.2-0.0
Run reversals in cocaine runway, males0.40.30.6-0.6-0.50.5-0.50.6-0.50.40.60.50.6-0.6-0.50.50.80.70.7-0.7-0.60.7-0.8
Latency to leave start box in cocaine runway0.30.30.40.50.6-0.60.5-0.30.4-0.6-0.5-0.6-0.50.50.6-0.5-0.5-0.6-0.60.60.5-0.60.5
Latency to leave start box in cocaine runway, F0.10.10.20.20.4-0.40.3-0.00.2-0.3-0.2-0.4-0.20.20.3-0.4-0.2-0.3-0.30.30.2-0.30.2
Latency to leave start box in cocaine runway, M0.20.20.30.40.5-0.50.4-0.30.4-0.5-0.5-0.5-0.50.50.5-0.3-0.4-0.4-0.40.50.5-0.50.4
Std. dev. time between licks in bursts0.00.00.20.20.5-0.40.10.00.10.0-0.0-0.10.0-0.00.0-0.2-0.00.00.0-0.0-0.00.00.0
Total sessions with >9 infusions1.61.82.71.31.2-1.41.3-1.31.2-1.6-1.4-1.2-1.41.41.3-1.4-1.6-1.1-1.11.31.4-1.31.6
Short access day 1 total inactive lever presses0.10.10.5-0.4-0.20.4-0.30.4-0.5-0.00.30.10.3-0.3-0.10.7-0.20.30.3-0.4-0.30.4-0.1
Short access day 10 total inactive lever presses1.92.12.5-1.6-1.51.5-1.61.6-1.51.31.51.41.5-1.5-1.51.41.11.51.5-1.6-1.51.6-1.0
Short access day 1 total infusions0.00.00.3-0.1-0.20.4-0.20.1-0.3-0.10.10.20.1-0.1-0.10.5-0.10.20.2-0.2-0.10.2-0.1
Short access day 10 total infusions0.20.30.90.50.5-0.30.6-0.50.5-1.0-0.6-0.5-0.60.60.7-0.1-0.7-0.1-0.10.20.6-0.20.6
Short access total infusions0.00.00.20.1-0.10.1-0.00.0-0.1-0.4-0.10.1-0.10.10.10.3-0.40.10.1-0.00.20.00.2
Short access day 1 locomotion0.30.40.8-0.7-0.70.8-0.60.7-0.80.30.50.70.5-0.5-0.50.90.20.50.5-0.6-0.40.5-0.3
Short access day 10 total locomotion0.30.40.5-0.6-0.60.5-0.60.7-0.70.50.60.70.6-0.6-0.60.60.70.50.5-0.5-0.50.5-0.5
Short access total locomotion0.10.10.30.30.1-0.10.2-0.20.2-0.5-0.4-0.1-0.40.40.3-0.1-0.6-0.2-0.20.30.5-0.30.5
One hour access (0.3 mA shock)0.00.00.10.30.10.10.1-0.30.1-0.4-0.1-0.1-0.10.10.10.1-0.30.30.3-0.30.10.30.1
Compulsive drug intake5.95.98.8-3.0-2.62.3-2.72.9-2.62.52.52.52.5-2.5-2.62.22.22.22.2-2.1-2.32.1-2.2
One hour access (shock baseline)2.83.24.72.21.9-1.71.9-2.01.9-1.9-1.9-1.8-1.91.91.8-1.7-1.9-1.5-1.51.51.8-1.41.8
Social response proportion1.01.11.8-1.3-1.00.9-1.21.3-1.21.31.21.11.1-1.1-1.20.90.90.80.8-0.8-1.10.9-0.9
Social responses0.40.51.00.10.6-0.70.6-0.30.3-0.8-0.7-0.7-0.70.70.8-0.4-0.9-1.0-1.01.00.9-0.90.8
Social time0.10.20.7-0.7-0.50.5-0.50.6-0.80.20.20.30.2-0.2-0.10.8-0.0-0.3-0.30.50.0-0.40.1
Soleus weight0.10.30.60.70.4-0.60.5-0.80.7-0.5-0.5-0.5-0.50.50.4-0.7-0.5-0.5-0.50.50.5-0.50.5
Bone: stiffness0.20.30.60.50.8-0.70.6-0.50.6-0.5-0.5-0.7-0.50.50.5-0.7-0.4-0.3-0.30.30.4-0.30.4
Tibialis anterior weight8.027.228.6-5.2-5.35.3-5.35.1-5.25.25.25.35.2-5.2-5.25.35.25.25.2-5.2-5.25.2-5.2
Time to tail flick, vehicle, before self-admin1.51.52.3-1.1-1.01.2-1.01.1-1.11.01.21.01.3-1.3-0.91.31.51.51.5-1.3-1.31.3-1.5
Time to tail flick, vehicle, after self-admin1.71.82.6-1.1-1.11.2-1.21.4-1.21.51.31.31.3-1.3-1.31.11.61.41.4-1.4-1.31.4-1.6
Time to tail flick, test, before self-admin0.20.20.3-0.6-0.40.5-0.40.5-0.50.40.40.30.5-0.5-0.30.40.30.60.6-0.4-0.40.5-0.3
Time to tail flick, test, after self-admin0.00.00.10.0-0.10.2-0.10.1-0.00.20.20.10.2-0.2-0.20.10.10.40.4-0.2-0.20.3-0.0
Delta time to tail flick, vehicle, before/after SA0.20.20.30.50.3-0.50.3-0.30.50.0-0.4-0.2-0.40.40.2-0.6-0.4-0.5-0.50.50.4-0.40.4
Delta time to tail flick, test, before/after SA0.10.10.2-0.2-0.30.2-0.40.4-0.20.50.40.40.4-0.4-0.40.10.30.40.4-0.4-0.40.4-0.3
Tibia length2.46.97.72.72.6-2.52.8-2.82.7-2.7-2.7-2.7-2.72.72.7-2.7-2.5-2.4-2.42.52.6-2.52.5
Ambulatory time before self-admin0.40.41.00.81.0-0.71.0-0.80.8-0.4-0.6-1.0-0.50.51.0-0.7-0.1-0.4-0.40.20.4-0.10.1
Ambulatory time after self-admin0.20.20.70.20.20.20.3-0.00.30.30.2-0.30.3-0.30.10.00.80.60.6-0.8-0.40.8-0.8
Bone: tissue strength0.50.50.6-0.8-0.50.4-0.70.6-0.60.70.70.70.7-0.7-0.80.20.80.80.8-0.8-0.70.7-0.8
Total heroin consumption0.91.11.61.21.2-1.11.2-1.21.2-0.6-1.0-1.1-0.90.91.1-1.3-0.9-0.9-0.90.90.8-0.90.9
Bone: trabecular number0.00.10.10.20.2-0.30.2-0.10.2-0.2-0.2-0.2-0.20.20.2-0.3-0.3-0.2-0.20.20.2-0.20.3
Bone: trabecular spacing0.00.00.10.10.3-0.10.2-0.20.1-0.1-0.1-0.1-0.10.10.2-0.1-0.1-0.1-0.10.10.1-0.10.1
Bone: trabecular thickness0.00.00.10.00.3-0.30.1-0.00.1-0.2-0.2-0.3-0.20.20.2-0.2-0.2-0.2-0.20.20.2-0.20.2
Bone: trabecular tissue density16.122.623.94.74.8-4.94.8-4.64.7-4.7-4.8-4.8-4.84.84.7-4.8-4.7-4.8-4.84.84.8-4.84.7
Water consumed over 24 hours0.10.10.2-0.1-0.0-0.0-0.30.1-0.20.40.30.20.3-0.3-0.5-0.20.40.50.5-0.5-0.40.5-0.4
Number of responses in last shaping day0.30.40.80.80.6-0.00.8-0.70.7-0.8-0.7-0.7-0.70.70.90.3-0.6-0.3-0.30.30.6-0.40.6