Hub : Genes

Sgsm2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS XM_006246740.4 0.04 0.03 6.6e-04 0.03 0.02 0.01 0.02 7.5e-04 6.4e-03 1.3e-02 2.0e-03
2 Liver alternative TSS XM_006246740.4 0.06 0.06 1.2e-04 0.02 0.02 0.01 0.02 1.7e-03 4.5e-03 8.6e-03 9.0e-04
3 Adipose mRNA stability Sgsm2 0.02 0.02 9.4e-03 0 0 0 0 1.9e-01 1.5e-01 1.5e-01 2.9e-01
4 Adipose gene expression Sgsm2 0.11 0.06 1.8e-13 0.07 0.09 0.09 0.09 5.5e-08 2.0e-10 5.5e-10 3.3e-10
5 IC mRNA stability Sgsm2 0.21 0.12 1.3e-08 0.17 0.19 0.17 0.18 7.8e-08 2.3e-08 1.1e-07 4.0e-08
6 pVTA mRNA stability Sgsm2 0.08 0.05 8.8e-07 0.08 0.08 0.06 0.08 5.3e-07 8.1e-07 6.0e-06 1.0e-06
7 Brain alternative TSS XM_039086013.2 0.02 0.02 7.5e-03 0.02 0.01 0.01 0.01 9.8e-03 4.9e-02 5.7e-02 3.6e-02
8 Brain alternative TSS XM_039086013.2 0.02 0.02 7.7e-03 0.02 0.01 0.01 0.01 1.0e-02 5.1e-02 6.3e-02 3.5e-02
9 Brain gene expression Sgsm2 0.15 0.08 8.3e-16 0.15 0.17 0.16 0.16 9.2e-14 2.0e-15 1.4e-14 1.2e-14
10 PL mRNA stability Sgsm2 0.36 0.14 0.0e+00 0.3 0.29 0.29 0.3 1.4e-33 1.8e-31 1.4e-31 1.3e-32
11 NAcc mRNA stability Sgsm2 0.14 0.08 0.0e+00 0.15 0.15 0.14 0.15 2.0e-22 8.7e-22 2.7e-21 5.7e-22
12 IL mRNA stability Sgsm2 0.48 0.18 2.8e-09 0.26 0.15 0.23 0.25 5.2e-07 2.2e-04 2.4e-06 1.1e-06
13 OFC gene expression Sgsm2 0.17 0.12 2.1e-03 0.08 0.06 0.06 0.06 7.1e-03 1.2e-02 1.4e-02 1.9e-02
14 IC gene expression Sgsm2 0.32 0.16 5.0e-10 0.26 0.17 0.24 0.25 2.5e-11 1.0e-07 1.2e-10 6.7e-11
15 PL gene expression Sgsm2 0.1 0.06 6.0e-14 0.14 0.13 0.12 0.13 1.3e-14 1.1e-13 1.5e-13 6.9e-14
16 BLA mRNA stability Sgsm2 0.37 0.27 3.0e-09 0.14 0.13 0.13 0.13 7.0e-08 2.3e-07 3.0e-07 2.5e-07
17 Liver mRNA stability Sgsm2 0.04 0.04 7.9e-03 0.01 0.01 0.01 0.01 6.8e-02 6.2e-02 3.7e-02 4.9e-02
18 Brain mRNA stability Sgsm2 0.2 0.1 0.0e+00 0.23 0.23 0.22 0.23 8.0e-21 2.7e-21 8.8e-21 4.1e-21
19 LHb mRNA stability Sgsm2 0.15 0.11 6.6e-03 0.09 0.04 0.12 0.07 3.8e-03 3.1e-02 7.9e-04 7.9e-03
20 OFC mRNA stability Sgsm2 0.28 0.18 2.3e-04 0.12 0.14 0.11 0.13 7.7e-04 3.8e-04 1.4e-03 6.2e-04
21 IL gene expression Sgsm2 0.15 0.1 9.7e-03 0.03 0.06 0.04 0.03 6.7e-02 1.6e-02 3.7e-02 6.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density1.42.79.23.0-3.02.3-2.01.9-1.4-1.4-1.4-1.5-1.2-1.4-1.41.41.41.4-1.50.81.0-0.80.9-0.3
Area under the delay curve0.20.30.7-0.60.6-0.90.8-0.60.20.30.30.60.80.60.8-0.8-0.5-0.50.5-0.2-0.40.3-0.50.1
BMI with tail0.62.24.72.1-2.12.2-1.81.8-1.8-1.5-1.5-1.6-1.1-1.3-1.21.21.31.3-1.30.31.2-0.91.1-0.9
BMI without tail0.10.74.11.3-1.30.6-0.10.10.20.50.50.30.80.70.7-0.7-0.7-0.70.72.0-0.80.9-0.91.2
Body weight0.83.412.81.4-1.4-0.10.7-0.81.41.61.61.42.11.81.9-1.9-1.8-1.81.73.6-2.01.9-2.22.6
Weight adjusted by age0.61.62.81.7-1.71.3-1.31.4-1.7-1.6-1.6-1.3-0.9-0.9-0.90.91.31.3-1.0-0.91.1-1.51.0-1.1
Bone surface2.14.18.62.9-2.92.8-2.52.4-2.1-2.1-2.1-2.0-1.7-1.8-1.81.82.02.0-2.00.31.6-1.01.5-1.0
Bone volume2.14.29.23.0-3.02.8-2.52.4-2.1-2.0-2.0-2.1-1.7-1.9-1.91.92.02.0-2.00.31.6-1.01.5-1.0
Breakpoint value in progressive ratio session0.10.21.21.1-1.10.3-0.10.10.10.00.00.10.40.40.4-0.4-0.4-0.40.50.7-0.4-0.3-0.50.7
Number of licking bursts0.10.20.9-0.20.2-0.60.5-0.40.40.30.30.30.20.40.4-0.4-0.3-0.30.3-1.0-0.2-0.6-0.20.0
Context. condit. distance diff. score0.40.52.91.7-1.70.8-0.70.7-0.5-0.4-0.4-0.5-0.2-0.3-0.30.30.50.5-0.50.30.2-0.50.10.1
Locomotion velocity, session 10.30.41.91.3-1.30.8-0.60.40.20.10.1-0.10.00.10.2-0.2-0.2-0.20.21.4-0.30.4-0.30.8
Locomotion distance, session 10.30.40.80.7-0.70.9-0.90.8-0.6-0.6-0.6-0.7-0.8-0.7-0.80.80.50.5-0.5-0.10.6-0.40.6-0.3
Locomotion velocity, session 20.20.20.80.9-0.90.7-0.70.6-0.3-0.3-0.3-0.5-0.5-0.4-0.50.50.30.3-0.30.30.3-0.20.30.0
Locomotion distance, session 20.81.22.51.6-1.61.4-1.41.3-1.1-1.0-1.0-1.2-1.1-0.9-1.11.10.80.8-0.9-0.00.9-0.90.9-0.6
Locomotion velocity, session 33.43.99.7-3.13.1-2.52.3-2.31.81.71.72.01.61.81.8-1.8-1.8-1.81.90.4-1.71.6-1.51.2
Locomotion distance, session 30.20.20.4-0.30.30.4-0.40.3-0.7-0.6-0.6-0.4-0.6-0.5-0.50.50.50.5-0.5-0.20.5-0.30.5-0.5
Stereotopy head waving bouts, day 30.50.61.0-0.50.5-0.70.7-0.80.90.80.80.80.60.80.7-0.7-1.0-1.00.90.8-0.90.8-0.81.0
Stereotopy head waving duration, day 30.00.00.2-0.30.3-0.30.1-0.10.20.20.20.1-0.3-0.1-0.10.1-0.2-0.20.1-0.40.0-0.10.1-0.0
Locomotion velocity, session 70.91.01.90.9-0.91.4-1.21.2-1.3-1.0-1.0-1.2-0.9-0.8-0.80.80.90.9-0.9-0.21.0-0.70.9-0.9
Locomotion distance, session 71.72.14.01.8-1.81.8-1.71.8-2.0-1.5-1.5-1.6-1.2-1.2-1.11.11.41.4-1.4-0.51.3-1.31.2-1.1
Stereotopy head waving bouts, day 70.10.10.70.8-0.80.5-0.40.30.1-0.0-0.0-0.1-0.3-0.2-0.10.10.00.0-0.00.8-0.10.1-0.00.5
Stereotopy head waving duration, day 70.40.41.31.1-1.11.0-0.90.7-0.3-0.5-0.5-0.6-0.8-0.7-0.60.60.50.5-0.50.50.4-0.30.50.0
Locomotion velocity, session 80.50.60.80.9-0.90.7-0.80.7-0.7-0.9-0.9-0.7-0.7-0.8-0.80.80.90.9-0.9-0.20.6-0.70.6-0.4
Locomotion distance, session 80.50.74.42.1-2.11.1-1.01.0-0.7-0.4-0.4-0.6-0.3-0.3-0.30.30.40.4-0.40.70.2-0.50.10.2
Degree of sensitization distance0.30.32.01.4-1.40.6-0.50.7-0.5-0.2-0.2-0.40.1-0.00.0-0.00.20.2-0.20.30.1-0.2-0.10.1
Degree of sensitization stereotypy0.20.21.31.1-1.10.7-0.50.4-0.0-0.2-0.2-0.2-0.3-0.2-0.20.20.20.2-0.20.70.00.00.00.4
Conditioned locomotion0.10.10.6-0.80.8-0.40.2-0.30.30.20.20.1-0.30.10.0-0.0-0.2-0.20.2-0.40.1-0.10.2-0.1
Cocaine response after cond. corrected0.20.30.60.1-0.1-0.50.5-0.50.60.60.60.60.50.60.6-0.6-0.5-0.50.50.6-0.70.4-0.70.8
Cocaine response after cond. not corrected0.10.20.60.4-0.4-0.20.2-0.30.50.40.40.40.40.50.5-0.5-0.4-0.40.40.8-0.50.5-0.60.7
Cocaine response before conditioning0.30.41.20.9-0.91.1-0.90.8-0.5-0.6-0.6-0.7-0.5-0.4-0.40.40.50.5-0.50.40.5-0.00.4-0.2
Saline control response0.81.11.61.0-1.01.2-1.21.2-1.3-1.1-1.1-1.1-1.1-1.0-1.11.11.11.1-1.1-0.61.1-0.81.0-1.0
Bone: connectivity density2.64.111.33.4-3.42.9-2.62.4-1.8-1.8-1.8-2.0-1.7-1.9-1.91.91.91.9-1.90.71.5-1.01.4-0.7
Bone: cortical apparent density0.20.41.7-0.10.10.1-0.30.4-0.7-0.4-0.4-0.6-0.7-0.5-0.60.60.40.4-0.4-1.30.7-0.90.7-0.9
Bone: cortical area0.61.03.3-1.81.8-1.31.3-1.20.40.70.71.01.21.00.9-0.9-0.8-0.80.8-0.1-0.70.9-0.80.2
Bone: cortical porosity0.10.10.40.6-0.60.2-0.20.2-0.2-0.2-0.2-0.10.1-0.00.0-0.00.10.1-0.10.3-0.0-0.1-0.10.1
Bone: cortical porosity0.00.00.10.2-0.2-0.10.2-0.10.10.10.10.20.30.20.2-0.2-0.2-0.20.10.2-0.20.1-0.30.2
Bone: cortical thickness4.06.613.0-3.63.6-3.23.1-3.02.22.52.52.72.72.52.5-2.5-2.4-2.42.40.6-2.32.2-2.21.5
Bone: cortical thickness2.43.03.6-1.71.7-1.81.8-1.81.51.81.81.81.91.71.8-1.8-1.9-1.91.81.2-1.71.6-1.71.4
Bone: cortical tissue density0.20.31.40.0-0.00.1-0.40.4-0.6-0.4-0.4-0.5-0.7-0.5-0.60.60.40.4-0.4-1.20.7-0.90.7-0.8
Condit. Reinf. active minus inactive responses0.60.71.1-0.90.9-0.70.8-0.81.00.90.90.80.80.90.8-0.8-0.9-0.90.90.6-0.71.0-0.70.7
Condit. Reinf. active-inactive response ratio4.85.26.0-2.32.3-2.22.4-2.42.32.32.32.32.32.42.4-2.4-2.4-2.42.41.5-2.22.4-2.11.9
Condit. Reinf. active responses0.10.20.30.5-0.50.6-0.50.5-0.3-0.3-0.3-0.5-0.4-0.4-0.40.40.20.2-0.3-0.10.4-0.20.4-0.3
Condit. Reinf. inactive responses5.87.58.72.7-2.72.7-2.92.9-2.7-2.6-2.6-2.8-2.8-3.0-2.92.92.72.7-2.8-2.02.7-2.92.7-2.4
Incentive salience index mean0.81.12.0-1.01.0-0.70.9-1.01.21.11.11.00.91.10.9-0.9-1.2-1.21.21.1-1.01.4-0.91.0
Condit. Reinf. lever presses0.71.13.2-0.30.3-0.30.6-0.71.21.11.10.91.01.01.0-1.0-1.1-1.11.11.8-1.11.5-1.11.3
Condit. Reinf. active minus inactive responses0.60.91.71.3-1.31.0-1.01.0-1.2-1.0-1.0-0.9-0.6-0.9-0.80.80.90.9-0.9-0.30.8-0.80.7-0.7
Condit. Reinf. active-inactive response ratio0.10.10.30.1-0.1-0.40.4-0.30.10.30.30.40.60.40.4-0.4-0.3-0.30.30.3-0.40.2-0.50.3
Condit. Reinf. active responses2.33.34.61.9-1.92.0-1.92.0-2.1-1.9-1.9-1.9-1.6-1.8-1.81.81.91.9-1.9-1.01.8-1.51.7-1.6
Condit. Reinf. inactive responses5.17.59.12.1-2.13.0-3.03.0-3.0-2.9-2.9-3.0-2.7-2.9-2.92.92.82.8-2.9-1.82.8-2.12.8-2.6
Condit. Reinf. lever presses1.11.62.30.3-0.30.9-1.11.1-1.3-1.4-1.4-1.3-1.4-1.5-1.51.51.41.4-1.4-1.41.4-1.31.4-1.5
Condit. Reinf. lever reinforcers received2.63.75.31.8-1.82.1-2.02.1-2.3-2.0-2.0-2.0-1.7-1.9-1.91.92.02.0-2.0-1.21.9-1.61.8-1.8
Conditioned reinforcement - actives0.52.13.31.7-1.71.8-1.81.7-1.7-1.5-1.5-1.6-1.4-1.4-1.41.41.31.3-1.3-0.61.4-1.01.3-1.2
Conditioned reinforcement - inactives0.20.61.21.1-1.10.9-0.80.9-1.1-0.7-0.7-0.8-0.5-0.5-0.60.60.50.5-0.5-0.50.7-0.90.6-0.7
Conditioned locomotion0.10.20.4-0.40.40.3-0.30.3-0.7-0.5-0.5-0.4-0.4-0.3-0.30.30.30.3-0.3-0.50.5-0.00.5-0.6
Patch foraging indifference point 0 sec0.10.20.30.3-0.30.6-0.50.4-0.3-0.4-0.4-0.4-0.4-0.4-0.40.40.50.5-0.50.20.4-0.00.4-0.2
Patch foraging indifference point AUC0.40.92.00.4-0.40.5-0.60.8-1.1-0.9-0.9-0.8-0.8-0.9-0.90.91.11.1-1.1-1.41.0-1.10.9-1.1
Delay disc. indifference point, 0s delay0.20.30.50.6-0.60.6-0.50.5-0.4-0.7-0.7-0.5-0.4-0.5-0.40.40.70.7-0.6-0.10.4-0.30.4-0.3
Delay disc. indifference point, 16s delay0.10.20.4-0.30.3-0.70.5-0.3-0.4-0.2-0.20.30.60.50.6-0.6-0.4-0.40.4-0.5-0.1-0.0-0.2-0.3
Delay disc. indifference point, 2s delay0.30.30.7-0.40.4-0.90.7-0.60.50.40.40.60.70.50.7-0.7-0.5-0.50.50.2-0.40.6-0.50.2
Delay disc. indifference point, 24s delay0.00.10.20.1-0.1-0.20.2-0.1-0.3-0.3-0.30.00.30.10.3-0.3-0.2-0.20.1-0.50.0-0.5-0.0-0.2
Delay disc. indifference point, 4s delay0.50.51.0-0.10.1-0.90.9-0.70.40.50.50.81.00.91.0-1.0-0.6-0.60.8-0.2-0.7-0.0-0.80.5
Delay disc. indifference point, 8s delay0.20.30.6-0.60.6-0.80.8-0.70.40.50.50.60.80.60.8-0.8-0.5-0.50.60.1-0.50.4-0.60.3
Indifference point function ln k0.00.10.60.4-0.40.6-0.40.30.1-0.1-0.1-0.2-0.2-0.1-0.10.10.00.0-0.00.80.00.30.00.3
Indifference point function log k0.00.10.60.4-0.40.6-0.40.30.1-0.1-0.1-0.2-0.2-0.1-0.10.10.00.0-0.00.80.00.30.00.3
Patch foraging total patch changes 0 sec0.10.30.50.4-0.40.7-0.70.6-0.4-0.6-0.6-0.6-0.6-0.6-0.60.60.70.7-0.70.10.5-0.20.5-0.3
Patch foraging total patch changes 12 sec0.40.50.9-0.90.9-0.80.8-0.80.90.80.80.80.60.70.7-0.7-0.5-0.50.50.3-0.70.8-0.60.6
Patch foraging total patch changes 18 sec0.10.20.6-0.30.3-0.70.7-0.60.30.20.20.60.80.50.5-0.5-0.2-0.20.20.1-0.50.2-0.60.3
Patch foraging total patch changes 24 sec0.00.10.4-0.70.7-0.50.5-0.40.30.20.20.30.20.30.3-0.3-0.2-0.20.3-0.2-0.20.1-0.1-0.0
Patch foraging total patch changes 6 sec0.40.61.10.0-0.00.5-0.60.6-0.7-0.8-0.8-0.7-0.8-0.9-0.90.91.01.0-1.0-0.90.8-0.70.9-0.9
Patch foraging time to switch 0 sec1.14.05.0-1.31.3-2.02.1-2.12.22.22.22.12.12.12.1-2.1-2.2-2.22.21.6-2.11.6-2.02.0
Patch foraging water rate 0 sec0.51.92.70.3-0.31.3-1.41.4-1.5-1.4-1.4-1.5-1.6-1.5-1.51.51.51.5-1.5-1.41.5-0.91.6-1.5
Patch foraging water rate 12 sec0.00.00.10.2-0.20.2-0.20.2-0.3-0.1-0.1-0.20.0-0.1-0.10.10.00.0-0.0-0.10.1-0.10.0-0.2
Patch foraging water rate 18 sec1.12.54.11.9-1.92.0-2.02.0-1.5-1.4-1.4-1.8-1.7-1.6-1.61.61.51.5-1.5-0.61.5-1.01.4-1.1
Patch foraging water rate 24 sec0.40.61.00.0-0.00.9-0.90.8-0.7-0.5-0.5-0.9-1.0-0.9-0.90.90.70.7-0.7-0.60.9-0.20.9-0.8
Patch foraging water rate 6 sec0.10.20.8-0.40.40.1-0.20.3-0.3-0.1-0.1-0.4-0.5-0.5-0.50.50.20.2-0.3-0.90.5-0.40.6-0.7
Seeking ratio, delayed vs. immediate footshock0.20.31.3-0.30.3-0.2-0.00.2-0.7-0.8-0.8-0.3-0.4-0.5-0.50.50.70.7-0.5-1.10.6-0.60.6-0.9
Distance traveled before self-admin0.30.62.0-1.41.4-1.41.2-0.90.40.20.20.70.60.70.6-0.6-0.6-0.60.7-0.4-0.30.6-0.3-0.3
Distance traveled after self-admin0.10.10.4-0.50.5-0.50.4-0.3-0.1-0.1-0.10.20.30.40.4-0.4-0.5-0.50.7-0.3-0.10.2-0.2-0.1
Extensor digitorum longus weight3.815.025.04.7-4.75.0-4.74.5-3.7-3.7-3.7-4.2-4.0-3.9-3.93.93.83.8-3.9-0.73.5-2.83.5-2.5
Bone: elastic displacement0.10.10.5-0.60.6-0.10.0-0.0-0.1-0.1-0.1-0.2-0.3-0.4-0.40.40.30.3-0.3-0.70.3-0.20.4-0.5
Bone: elastic work3.34.311.7-3.43.4-2.42.4-2.42.02.02.02.01.81.81.8-1.8-1.8-1.81.90.6-1.62.1-1.51.1
Bone: endosteal estimation0.30.81.20.8-0.81.0-1.01.0-1.1-1.1-1.1-1.0-1.0-0.8-0.80.80.90.9-0.8-0.60.9-0.70.9-0.9
Bone: endosteal perimeter1.94.65.82.0-2.02.2-2.22.3-2.4-2.4-2.4-2.2-2.0-2.1-2.12.12.22.2-2.2-1.52.1-1.92.0-2.0
Epididymis fat weight1.47.136.56.0-6.03.7-3.23.1-2.2-2.1-2.1-2.2-1.2-1.5-1.51.51.61.6-1.71.91.1-1.50.8-0.0
Delta time in closed arm before/after self-admin0.70.62.80.3-0.3-0.0-0.30.4-0.4-0.8-0.8-0.5-0.7-0.7-0.60.60.80.8-0.8-1.70.7-1.60.7-0.9
Delta time in open arm before/after self-admin0.20.32.30.9-0.90.7-0.40.3-0.4-0.1-0.1-0.20.10.10.1-0.10.20.2-0.11.5-0.00.9-0.10.3
Diff in mean of infusions in LGA sessions0.10.21.10.8-0.80.4-0.20.10.3-0.0-0.00.10.10.20.2-0.2-0.0-0.00.21.0-0.40.3-0.40.7
Delay discount exponential model param0.20.30.70.6-0.60.8-0.80.6-0.2-0.3-0.3-0.6-0.8-0.6-0.80.80.50.5-0.60.20.5-0.20.5-0.1
Extinction: sum of active levers before priming1.92.86.42.5-2.52.0-1.91.9-1.8-1.8-1.8-1.7-1.5-1.5-1.51.51.41.4-1.4-0.61.4-1.81.3-1.1
Active lever presses in extinction session 61.61.63.51.9-1.91.6-1.51.5-1.3-1.4-1.4-1.3-1.1-1.1-1.11.11.31.3-1.2-0.11.0-1.00.9-0.7
Bone: final force2.03.35.0-2.12.1-1.51.8-1.91.71.61.61.81.91.91.9-1.9-1.7-1.71.71.8-1.82.2-1.71.6
Bone: final moment1.52.54.1-2.02.0-1.31.6-1.71.41.41.41.61.61.61.6-1.6-1.4-1.41.41.6-1.52.0-1.51.4
Food consumed during 24 hour testing period0.10.20.70.8-0.80.6-0.50.4-0.3-0.5-0.5-0.3-0.3-0.4-0.40.40.40.4-0.50.30.2-0.30.2-0.1
Glucose0.71.24.6-2.12.1-1.81.6-1.40.80.60.61.11.00.70.8-0.8-0.7-0.70.7-0.8-0.60.3-0.6-0.0
Heart weight0.30.53.20.8-0.80.4-0.0-0.10.50.60.60.40.50.40.5-0.5-0.3-0.30.41.8-0.70.7-0.71.1
Delay discount hyperbolic model param0.40.51.10.8-0.71.0-1.00.8-0.5-0.6-0.6-0.8-0.9-0.8-0.90.90.70.7-0.70.10.6-0.40.7-0.3
Intermittent access intake day 1-15 change0.42.03.20.6-0.60.8-1.01.1-1.6-1.7-1.7-1.3-1.4-1.4-1.41.41.41.4-1.3-1.71.5-1.71.5-1.8
Intermittent access intake escalation0.42.23.60.6-0.60.9-1.11.2-1.7-1.9-1.9-1.5-1.4-1.5-1.51.51.51.5-1.4-1.81.7-1.61.6-1.9
Intermittent access intake escalation 20.91.52.80.1-0.10.5-0.80.8-1.1-1.4-1.4-1.1-1.3-1.3-1.31.31.41.4-1.2-1.71.3-1.31.4-1.6
Intermitt. access day 1 inactive lever presses0.10.73.0-1.61.6-0.20.00.1-0.6-0.5-0.5-0.4-0.5-0.6-0.60.60.70.7-0.7-1.70.8-0.40.8-1.2
Intermitt. access day 15 inactive lever presses0.21.36.00.2-0.20.0-0.40.7-1.1-1.2-1.2-0.8-0.9-1.0-1.01.01.01.0-1.1-2.51.1-2.01.1-1.6
Intermitt. access escalation Index0.72.23.8-0.10.1-1.01.2-1.31.61.61.61.51.51.51.5-1.5-1.6-1.61.51.9-1.71.4-1.71.8
Intermittent access day 1 total infusions0.00.10.30.6-0.60.2-0.20.4-0.6-0.5-0.5-0.3-0.1-0.1-0.10.10.00.0-0.1-0.50.2-0.60.2-0.4
Intermittent access day 15 total infusions1.02.54.41.3-1.31.3-1.41.5-2.0-2.1-2.1-1.6-1.5-1.5-1.51.51.41.4-1.5-1.51.6-1.71.6-1.7
Intermittent access terminal intake (last 3 days)1.22.03.21.5-1.51.3-1.41.5-1.6-1.8-1.8-1.4-1.3-1.4-1.41.41.41.4-1.4-0.91.4-1.31.3-1.3
Intermittent access total infusions1.21.42.71.2-1.20.9-1.01.2-1.5-1.6-1.6-1.2-1.0-1.0-1.01.01.01.0-1.1-1.21.2-1.41.1-1.3
Intermittent access day 1 locomotion0.10.20.4-0.40.4-0.40.4-0.30.00.20.20.30.50.60.6-0.6-0.6-0.60.6-0.2-0.30.2-0.40.1
Intermittent access day 15 total locomotion0.10.30.90.1-0.10.3-0.30.5-0.9-0.8-0.8-0.5-0.4-0.4-0.40.40.30.3-0.2-1.00.6-0.60.6-0.9
Intermittent access total locomotion0.30.40.90.4-0.40.5-0.50.6-1.0-0.9-0.9-0.7-0.4-0.4-0.40.40.40.4-0.4-0.90.7-0.80.6-0.9
Intermittent access standard deviation1.15.77.61.3-1.31.8-2.12.2-2.6-2.7-2.7-2.4-2.4-2.5-2.52.52.52.5-2.5-2.72.6-2.52.5-2.8
Left kidney weight1.411.613.9-3.13.1-3.63.7-3.73.33.43.43.63.73.63.6-3.6-3.6-3.63.62.2-3.43.0-3.42.9
Right kidney weight1.812.415.5-2.72.7-3.63.7-3.63.53.73.73.73.93.83.8-3.8-3.8-3.83.72.5-3.63.1-3.63.2
Cocaine induced anxiety0.00.10.4-0.40.40.0-0.10.1-0.1-0.1-0.1-0.2-0.4-0.4-0.40.40.50.5-0.5-0.60.3-0.00.4-0.4
Post-drug Anxiety0.40.51.2-0.30.3-0.40.4-0.51.01.01.00.60.50.50.5-0.5-0.4-0.40.41.0-0.71.1-0.71.0
Baseline Anxiety0.30.41.70.6-0.6-0.00.2-0.30.70.70.70.50.50.50.5-0.5-0.6-0.60.61.3-0.70.6-0.71.0
Tail length1.57.914.7-0.20.2-1.72.2-2.43.12.82.82.83.13.03.0-3.0-2.8-2.82.93.8-3.22.8-3.33.6
Length with tail2.611.617.2-0.50.5-2.52.9-3.03.83.53.53.53.83.73.7-3.7-3.6-3.63.54.1-3.83.3-3.94.2
Length without tail0.41.94.00.4-0.4-0.70.9-1.01.51.41.41.31.61.41.5-1.5-1.4-1.41.32.0-1.61.3-1.71.9
Times rat made contact with spout2.32.63.7-1.91.9-1.51.7-1.71.51.61.61.61.71.61.6-1.6-1.6-1.61.61.1-1.51.8-1.51.3
Lifetime Intake0.91.12.21.1-1.10.9-0.91.1-1.4-1.5-1.5-1.1-0.9-0.9-0.90.90.90.9-1.0-1.11.0-1.20.9-1.1
Liver weight, left3.76.414.00.8-0.8-1.11.5-1.62.32.52.52.22.83.02.9-2.9-2.9-2.92.83.7-2.82.4-2.93.3
Liver weight, right1.73.08.41.4-1.4-0.40.8-0.81.61.71.71.42.01.81.8-1.8-1.8-1.81.72.9-2.01.3-2.12.5
Locomotor activity0.10.20.80.9-0.90.4-0.40.5-0.7-0.5-0.5-0.40.1-0.1-0.10.10.20.2-0.1-0.20.2-0.60.1-0.3
Locomotor testing distance0.00.10.30.5-0.50.2-0.20.3-0.3-0.3-0.3-0.20.0-0.1-0.10.10.10.1-0.1-0.10.2-0.30.1-0.1
Locomotor testing rearing0.51.72.31.4-1.41.3-1.41.4-1.5-1.5-1.5-1.4-1.1-1.3-1.21.21.31.3-1.3-0.91.3-1.21.2-1.2
Locomotion in novel chamber2.02.65.4-0.30.30.8-1.11.2-1.6-1.9-1.9-1.6-1.8-1.9-1.91.91.71.7-1.7-1.91.9-0.92.0-2.3
Locomotion in novel chamber post-restriction0.30.91.50.8-0.80.9-1.00.9-0.8-0.9-0.9-0.9-1.1-1.1-1.21.21.21.2-1.2-0.11.0-0.61.0-0.8
Fecal boli incidents, locomotor time 10.10.41.7-0.60.6-0.40.5-0.60.90.70.70.50.30.30.3-0.3-0.3-0.30.31.1-0.51.3-0.40.6
Change in fecal boli incidents, locomotor task0.50.50.7-0.70.7-0.90.9-0.80.80.80.80.80.80.60.6-0.6-0.7-0.70.60.2-0.80.4-0.80.7
Time >=10cm from walls, locomotor time 10.10.20.40.0-0.00.6-0.50.4-0.4-0.3-0.3-0.4-0.5-0.5-0.50.50.40.4-0.50.10.40.20.4-0.3
Bouts of movement, locomotor time 10.00.10.30.1-0.10.2-0.10.10.4-0.1-0.1-0.1-0.2-0.3-0.30.30.10.1-0.20.60.00.50.10.1
Total resting periods, locomotor time 10.10.10.30.3-0.30.3-0.30.30.1-0.3-0.3-0.3-0.4-0.5-0.50.50.40.4-0.40.20.30.20.3-0.2
Rest time, locomotor task time 10.10.10.7-0.40.4-0.1-0.00.00.2-0.2-0.2-0.2-0.3-0.4-0.40.40.20.2-0.3-0.80.3-0.30.4-0.4
Distance moved, locomotor task time 10.00.10.30.6-0.60.4-0.40.4-0.5-0.4-0.4-0.4-0.2-0.2-0.20.20.20.2-0.30.00.3-0.20.3-0.3
Vertical activity count, locomotor time 10.10.50.90.8-0.81.0-0.90.8-0.8-0.6-0.6-0.7-0.7-0.6-0.70.70.70.7-0.70.50.60.10.6-0.4
Time >=10cm from walls, locomotor time 20.10.31.2-1.11.1-0.50.6-0.60.30.60.60.50.50.40.5-0.5-0.4-0.40.4-0.1-0.40.4-0.40.2
Bouts of movement, locomotor time 20.00.00.10.0-0.0-0.30.2-0.10.0-0.1-0.10.20.30.20.2-0.2-0.2-0.20.2-0.3-0.2-0.1-0.20.1
Total resting periods, locomotor time 20.00.00.10.2-0.20.1-0.10.1-0.1-0.3-0.3-0.10.1-0.1-0.00.0-0.0-0.0-0.1-0.20.0-0.2-0.0-0.0
Rest time, locomotor task time 20.20.40.80.9-0.90.5-0.60.7-0.5-0.9-0.9-0.6-0.4-0.5-0.50.50.50.5-0.5-0.70.6-0.80.5-0.6
Distance moved, locomotor task time 20.20.30.5-0.10.10.3-0.40.4-0.4-0.2-0.2-0.5-0.7-0.7-0.70.70.70.7-0.7-0.60.7-0.40.7-0.7
Vertical activity count, locomotor time 20.10.30.7-0.80.8-0.60.5-0.60.70.90.90.50.20.20.2-0.2-0.2-0.20.20.4-0.40.7-0.30.4
Light reinforcement 10.00.10.30.5-0.50.3-0.30.3-0.1-0.1-0.1-0.3-0.2-0.2-0.20.20.20.2-0.2-0.10.2-0.30.2-0.2
Light reinforcement 21.32.94.2-2.02.0-2.01.9-1.91.81.81.81.71.71.71.7-1.7-1.8-1.81.80.4-1.51.3-1.51.2
Bone: marrow area0.30.81.10.8-0.81.0-1.01.0-1.1-1.0-1.0-1.0-0.9-0.7-0.80.80.80.8-0.8-0.60.9-0.70.8-0.8
Bone: maximum diameter0.61.22.00.4-0.41.0-1.01.1-1.4-1.3-1.3-1.2-1.0-1.1-1.21.21.21.2-1.2-1.11.2-0.91.2-1.4
Bone: maximum force1.42.84.0-2.02.0-1.61.8-1.81.51.51.51.71.81.81.8-1.8-1.6-1.61.61.4-1.61.9-1.61.4
Bone: maximum moment1.12.03.5-1.91.9-1.41.5-1.61.21.21.21.41.41.51.4-1.4-1.3-1.31.31.1-1.31.7-1.31.1
Mean time between licks in bursts0.10.81.2-0.10.1-0.60.7-0.70.91.01.00.91.01.01.0-1.0-1.0-1.01.01.0-1.00.7-1.01.1
Mean num. licks in bursts0.30.93.0-1.11.1-0.50.8-0.80.70.80.80.81.10.80.8-0.8-0.8-0.80.81.6-0.91.7-0.90.9
Cd content in liver3.03.36.02.0-2.01.5-1.71.9-2.2-2.0-2.0-1.8-1.5-1.7-1.61.61.71.7-1.7-2.11.7-2.51.6-1.7
Co content in liver0.00.00.2-0.50.5-0.00.2-0.1-0.1-0.0-0.00.10.30.10.2-0.2-0.2-0.20.2-0.2-0.10.0-0.1-0.1
Cu content in liver0.40.41.4-1.21.2-0.80.8-0.70.50.50.50.60.50.60.6-0.6-0.7-0.70.7-0.3-0.40.1-0.40.2
Fe content in liver0.70.81.4-0.20.2-0.60.7-0.81.01.01.00.91.01.11.0-1.0-1.0-1.01.00.9-1.10.5-1.11.2
K content in liver1.91.82.5-1.21.2-0.91.2-1.31.61.41.41.41.31.41.4-1.4-1.4-1.41.41.4-1.41.3-1.41.4
Mg content in liver0.30.30.50.1-0.10.7-0.60.6-0.5-0.6-0.6-0.6-0.6-0.6-0.60.60.60.6-0.6-0.40.6-0.50.6-0.6
Mn content in liver0.70.81.40.6-0.61.0-1.00.9-0.6-0.8-0.8-0.9-1.1-1.0-1.01.01.01.0-1.0-0.50.9-1.21.0-0.7
Na content in liver2.12.44.3-2.12.1-1.71.7-1.71.31.41.41.51.51.61.5-1.5-1.5-1.51.51.1-1.31.9-1.30.9
Rb content in liver3.74.36.62.5-2.52.6-2.42.4-2.0-2.0-2.0-2.2-2.0-2.1-2.02.02.02.0-2.0-1.01.9-2.31.8-1.5
Se content in liver0.40.51.4-1.21.2-0.70.8-0.80.80.70.70.70.50.60.6-0.6-0.6-0.60.6-0.5-0.5-0.2-0.50.4
Sr content in liver1.51.31.81.2-1.21.3-1.31.2-1.1-1.1-1.1-1.2-1.3-1.2-1.21.21.21.2-1.2-0.31.1-0.91.1-0.8
Zn content in liver0.20.20.4-0.10.1-0.20.3-0.30.50.40.40.40.50.50.5-0.5-0.5-0.50.60.5-0.50.4-0.60.6
Bone: minimum diameter0.61.11.8-1.01.0-1.31.3-1.10.70.90.91.11.41.31.2-1.2-1.1-1.11.20.2-1.00.8-1.10.7
Time in familiar zone, hab. session 12.02.22.91.2-1.21.6-1.61.6-1.4-1.4-1.4-1.6-1.7-1.5-1.41.41.61.6-1.6-1.21.6-1.51.6-1.4
Time in novel zone, hab. session 11.82.02.7-0.80.8-1.61.5-1.41.41.41.41.51.61.61.6-1.6-1.6-1.61.60.9-1.51.2-1.51.3
Total zone transitions, hab. session 13.24.55.22.2-2.22.1-2.32.3-2.2-2.1-2.1-2.2-2.3-2.2-2.22.22.12.1-2.2-1.62.1-2.12.1-1.8
Total locomotion distance, hab. session 10.71.11.71.3-1.31.1-1.11.2-1.0-0.9-0.9-1.1-1.0-1.0-1.01.01.01.0-1.1-0.80.9-1.00.9-0.8
Locomotion velocity, hab. session 10.81.21.51.1-1.11.1-1.21.2-1.0-1.0-1.0-1.1-1.2-1.2-1.21.21.11.1-1.2-0.81.1-0.91.1-0.9
Time in familiar zone, hab. session 21.92.13.01.7-1.71.7-1.71.7-1.4-1.3-1.3-1.5-1.5-1.5-1.51.51.41.4-1.4-0.81.4-1.31.3-1.1
Time in novel zone, hab. session 24.14.56.6-2.62.6-2.52.5-2.41.91.91.92.32.12.22.2-2.2-2.1-2.12.11.0-2.01.9-2.01.6
Total zone transitions, hab. session 20.60.71.81.4-1.41.1-1.01.0-0.7-0.7-0.7-0.8-0.8-0.9-0.90.90.70.7-0.8-0.00.7-0.80.7-0.4
Total locomotion distance, hab. session 20.00.00.10.0-0.0-0.00.0-0.10.40.40.40.20.10.10.0-0.0-0.3-0.30.20.3-0.20.3-0.20.4
Locomotion velocity, hab. session 20.00.10.2-0.10.1-0.10.1-0.20.40.40.40.20.10.10.1-0.1-0.3-0.30.20.2-0.20.3-0.20.3
Novel to familiar place preference ratio0.30.40.7-0.20.20.4-0.40.4-0.6-0.7-0.7-0.6-0.5-0.7-0.70.70.70.7-0.6-0.60.7-0.50.7-0.8
Novelty place preference0.00.10.1-0.20.20.1-0.10.1-0.3-0.3-0.3-0.2-0.1-0.3-0.30.30.30.3-0.2-0.20.3-0.20.3-0.4
Time in novel zone, NPP test0.10.10.10.0-0.00.3-0.30.2-0.3-0.4-0.4-0.3-0.1-0.3-0.30.30.30.3-0.3-0.10.3-0.20.3-0.3
Total zone transitions, NPP test1.62.43.11.8-1.81.6-1.71.7-1.6-1.4-1.4-1.6-1.6-1.7-1.61.61.51.5-1.5-0.91.5-1.61.4-1.2
Total locomotion distance, NPP test0.91.21.50.8-0.80.9-1.11.1-1.2-1.1-1.1-1.2-1.2-1.2-1.21.21.11.1-1.1-1.21.1-1.11.1-1.1
Locomotion velocity, NPP test0.91.22.30.4-0.40.7-1.01.0-1.2-1.1-1.1-1.1-1.2-1.2-1.21.21.11.1-1.1-1.51.2-1.11.2-1.3
Intraocular pressure2.84.56.81.2-1.21.6-1.82.0-2.3-2.3-2.3-2.1-2.0-2.2-2.12.12.22.2-2.2-2.62.3-2.52.2-2.5
Delta distance traveled before/after self-admin0.20.31.31.1-1.11.0-0.80.7-0.4-0.2-0.2-0.4-0.2-0.2-0.20.20.20.2-0.10.40.1-0.30.00.3
Delta ambulatory time before/after self-admin0.20.31.11.1-1.11.0-0.80.7-0.3-0.2-0.2-0.4-0.4-0.3-0.30.30.10.1-0.10.60.2-0.10.10.2
Parametrial fat weight1.12.615.84.0-4.02.5-1.91.7-0.4-0.5-0.5-1.0-0.3-0.6-0.50.50.30.3-0.42.60.1-0.2-0.01.0
Pavlov. Cond. lever latency0.70.91.40.6-0.60.8-1.00.9-0.7-0.7-0.7-1.0-1.2-1.0-1.01.01.01.0-0.9-1.01.1-1.11.1-1.0
Pavlov. Cond. magazine entry latency0.60.81.7-0.20.2-0.50.7-0.71.00.70.70.80.91.00.8-0.8-1.0-1.00.91.3-1.01.0-1.01.1
Pavlov. Cond. change in total contacts0.40.40.8-0.70.7-0.90.8-0.80.60.50.50.70.70.70.7-0.7-0.8-0.80.70.0-0.60.4-0.60.4
Pavlov. Cond. index score0.81.12.3-0.30.3-0.60.8-0.91.00.80.81.01.21.11.1-1.1-1.2-1.21.11.5-1.21.2-1.21.3
Pavlov. Cond. latency score1.31.73.2-0.50.5-0.91.1-1.21.21.11.11.31.51.41.4-1.4-1.4-1.41.31.8-1.51.5-1.51.6
Pavlov. Cond. lever contacts0.70.81.3-0.60.6-0.70.9-0.90.70.70.71.01.11.01.0-1.0-0.9-0.90.81.0-1.01.0-1.01.0
Pavlov. Cond. magazine entry number0.10.10.3-0.10.10.1-0.20.2-0.4-0.1-0.1-0.3-0.3-0.3-0.30.30.40.4-0.3-0.50.4-0.40.4-0.5
Pavlov. Cond. intertrial magazine entries1.92.33.01.1-1.11.2-1.41.5-1.4-1.4-1.4-1.5-1.6-1.7-1.61.61.61.6-1.6-1.61.6-1.71.6-1.6
Pavlov. Cond. lever-magazine prob. diff.0.60.81.7-0.30.3-0.50.7-0.80.90.70.70.90.91.00.9-0.9-1.0-1.00.91.3-1.01.0-1.01.1
Pavlov. Cond. response bias0.30.30.90.1-0.1-0.20.4-0.40.70.40.40.60.60.60.6-0.6-0.7-0.70.61.0-0.70.7-0.70.8
Pavlov. Cond. lever latency0.10.20.90.6-0.60.7-0.40.30.20.20.2-0.1-0.20.20.1-0.1-0.2-0.20.21.0-0.10.5-0.10.5
Pavlov. Cond. magazine entry latency1.11.52.4-1.21.2-1.51.5-1.41.31.11.11.41.41.31.4-1.4-1.1-1.11.10.5-1.20.9-1.21.0
Pavlov. Cond. change in total contacts0.10.31.3-1.11.1-0.80.7-0.70.20.30.30.50.60.30.4-0.4-0.3-0.30.3-0.3-0.30.3-0.3-0.0
Pavlov. Cond. index score0.20.20.9-1.01.0-1.00.7-0.60.10.00.00.40.40.10.2-0.2-0.1-0.10.1-0.9-0.1-0.3-0.1-0.3
Pavlov. Cond. latency score0.20.31.2-1.11.1-1.00.7-0.60.10.00.00.40.40.10.2-0.2-0.1-0.10.1-1.0-0.1-0.3-0.0-0.4
Pavlov. Cond. lever contacts0.10.10.4-0.50.5-0.70.5-0.40.00.10.10.30.50.00.1-0.1-0.1-0.10.1-0.5-0.2-0.2-0.2-0.1
Pavlov. Cond. magazine entry number1.01.32.11.3-1.31.5-1.41.3-1.1-1.0-1.0-1.2-1.3-1.1-1.11.11.01.0-1.0-0.31.1-0.81.0-0.7
Pavlov. Cond. intertrial magazine entries1.02.34.01.8-1.82.0-1.91.9-1.6-1.4-1.4-1.7-1.6-1.4-1.41.41.31.3-1.3-0.51.5-1.01.4-1.1
Pavlov. Cond. lever-magazine prob. diff.0.10.20.8-0.90.9-0.90.7-0.50.10.00.00.30.40.10.1-0.1-0.1-0.10.1-0.9-0.1-0.3-0.1-0.4
Pavlov. Cond. response bias0.30.41.1-0.80.8-1.10.9-0.80.40.40.40.70.90.40.5-0.5-0.4-0.40.4-0.3-0.50.1-0.50.1
Time in closed arm before self-admin0.40.74.30.2-0.20.20.1-0.30.91.21.20.50.30.40.4-0.4-0.7-0.70.52.1-0.71.4-0.71.2
Time in closed arm after self-admin0.40.51.1-0.80.8-1.00.8-0.81.01.01.00.70.40.40.5-0.5-0.6-0.60.40.4-0.60.7-0.50.5
Time in open arm before self-admin0.50.63.0-1.31.3-1.31.0-0.70.0-0.3-0.30.50.70.70.7-0.7-0.4-0.40.6-1.7-0.2-0.8-0.2-0.4
Time in open arm after self-admin0.30.31.40.2-0.20.2-0.10.3-1.2-1.2-1.2-0.4-0.0-0.1-0.10.10.50.5-0.3-0.50.5-0.50.4-0.9
Bone: periosteal estimation0.10.20.6-0.80.8-0.40.5-0.4-0.10.20.20.30.40.50.5-0.5-0.3-0.30.4-0.1-0.20.4-0.3-0.0
Bone: periosteal perimeter0.20.40.80.0-0.00.4-0.40.5-0.9-0.8-0.8-0.6-0.4-0.5-0.60.60.70.7-0.6-0.80.7-0.50.6-0.9
Bone: post-yield work0.10.20.50.5-0.50.10.1-0.10.30.20.20.30.30.40.4-0.4-0.4-0.40.40.7-0.40.5-0.40.6
Progressive ratio test 1 active lever presses0.40.81.90.8-0.80.5-0.60.8-1.2-1.4-1.4-0.8-0.7-0.6-0.60.60.70.7-0.7-1.20.8-1.20.7-1.0
Progressive ratio test 1 breakpoint0.61.02.20.9-0.90.6-0.70.9-1.3-1.5-1.5-0.9-0.8-0.7-0.70.70.80.8-0.8-1.30.9-1.30.8-1.1
Progressive ratio test 1 inactive lever presses0.10.32.6-0.70.7-0.40.20.0-0.5-0.4-0.4-0.2-0.2-0.2-0.20.20.40.4-0.2-1.60.5-0.90.5-0.9
Progressive ratio test 2 active lever presses2.84.06.22.2-2.21.7-1.82.1-2.4-2.5-2.5-2.0-1.8-1.7-1.71.71.71.7-1.6-2.01.9-2.51.8-2.0
Progressive ratio test 2 breakpoint3.14.06.22.2-2.21.7-1.82.1-2.4-2.5-2.5-2.0-1.8-1.7-1.71.71.71.7-1.6-1.91.9-2.51.8-2.0
Progressive ratio test 2 inactive lever presses0.72.34.71.3-1.31.0-1.21.4-2.0-2.0-2.0-1.5-1.2-1.2-1.21.21.31.3-1.2-2.11.5-2.21.4-1.8
Incentive Sensitization - Responses1.33.65.82.2-2.21.8-1.92.1-2.3-2.1-2.1-2.0-1.7-1.5-1.61.61.51.5-1.4-1.81.9-2.41.7-1.9
Incentive Sensitization - Breakpoint1.43.15.02.0-2.01.6-1.71.9-2.1-2.0-2.0-1.8-1.6-1.5-1.51.51.51.5-1.3-1.71.7-2.21.6-1.7
Sum of active levers in priming session hrs 5-60.60.62.71.7-1.70.9-0.60.6-0.6-0.9-0.9-0.30.20.30.2-0.2-0.2-0.20.41.4-0.10.3-0.30.4
Progressive ratio0.20.50.9-0.20.20.5-0.50.5-0.5-0.6-0.6-0.6-0.9-0.9-1.01.00.90.9-0.9-0.20.7-0.10.8-0.7
Food seeking constrained by brief footshock0.00.00.1-0.30.3-0.10.0-0.10.30.30.30.0-0.2-0.2-0.20.2-0.2-0.2-0.1-0.30.1-0.20.1-0.1
Seeking ratio, punishment vs. effort0.61.32.3-0.80.8-1.31.2-1.21.21.21.21.21.21.21.3-1.3-1.5-1.51.40.2-1.10.6-1.10.9
Retroperitoneal fat weight0.10.74.42.1-2.10.6-0.70.8-0.7-0.7-0.7-0.5-0.0-0.4-0.30.30.40.4-0.4-0.30.3-1.10.2-0.2
Reaction time number correct0.00.00.1-0.00.00.3-0.20.1-0.2-0.1-0.1-0.10.00.10.1-0.1-0.1-0.10.10.30.00.30.00.0
Reaction time mean minus median0.10.40.80.1-0.10.3-0.50.5-0.3-0.5-0.5-0.6-0.8-0.9-0.80.80.70.7-0.8-0.90.7-0.80.8-0.6
Reaction time mean minus median AUC0.32.13.11.0-1.01.4-1.61.5-1.1-1.3-1.3-1.5-1.7-1.7-1.71.71.51.5-1.6-1.11.5-1.31.5-1.2
Reaction time num false alarms1.62.73.60.7-0.71.3-1.51.5-1.7-1.9-1.9-1.7-1.8-1.6-1.61.61.81.8-1.8-1.71.8-1.61.8-1.8
Reaction time num false alarms AUC1.02.23.10.5-0.51.3-1.41.4-1.6-1.8-1.8-1.6-1.7-1.4-1.41.41.61.6-1.6-1.51.7-1.41.7-1.7
Reaction time trials correct on left0.00.00.1-0.00.00.3-0.20.1-0.2-0.1-0.1-0.10.00.10.1-0.1-0.1-0.10.10.30.00.30.00.0
Reaction time trials on left0.00.00.10.0-0.00.4-0.20.2-0.2-0.2-0.2-0.2-0.00.00.1-0.1-0.1-0.10.10.20.10.30.1-0.0
Reaction time mean0.00.00.1-0.10.1-0.30.1-0.10.20.20.20.10.1-0.1-0.10.1-0.0-0.0-0.1-0.3-0.0-0.3-0.00.0
Reaction time mean AUC0.00.10.5-0.30.3-0.20.0-0.00.00.00.0-0.1-0.1-0.4-0.30.30.20.2-0.2-0.70.2-0.50.2-0.3
Median of all reaction times0.10.10.3-0.30.3-0.50.4-0.40.40.50.50.40.50.20.2-0.2-0.3-0.30.3-0.1-0.3-0.1-0.30.3
Reaction time omissions0.00.00.10.1-0.10.2-0.10.10.20.10.1-0.10.0-0.1-0.00.0-0.0-0.0-0.00.20.00.20.10.1
Reaction time false alarm rate1.21.72.40.4-0.41.0-1.21.2-1.3-1.5-1.5-1.3-1.6-1.3-1.31.31.51.5-1.5-1.41.4-1.41.5-1.5
Reaction time premature initiation rate0.40.71.51.2-1.21.0-0.90.9-0.6-0.7-0.7-0.8-0.8-0.8-0.80.80.80.8-0.8-0.20.7-0.90.6-0.5
Reaction time premature initiations0.30.81.51.2-1.21.2-1.11.0-0.8-0.8-0.8-0.9-0.9-0.9-0.90.90.80.8-0.8-0.20.8-0.80.8-0.6
Std. dev. reaction times0.10.30.6-0.30.30.3-0.50.4-0.1-0.3-0.3-0.5-0.7-0.8-0.70.70.60.6-0.7-0.70.6-0.50.7-0.5
Reaction time trials completed0.00.00.10.0-0.00.4-0.20.2-0.2-0.2-0.2-0.2-0.00.00.1-0.1-0.1-0.10.10.20.10.30.1-0.0
Reaction time trials AUC0.00.00.2-0.10.10.4-0.30.2-0.3-0.2-0.2-0.2-0.0-0.00.0-0.0-0.0-0.00.00.20.10.30.1-0.1
Run reversals in cocaine runway, females1.11.24.20.2-0.20.5-0.70.8-0.6-0.8-0.8-0.9-1.2-1.2-1.21.21.21.2-1.1-2.11.0-1.91.1-1.0
Run reversals in cocaine runway, males1.81.92.91.2-1.21.3-1.41.4-1.6-1.7-1.7-1.4-1.3-1.3-1.41.41.41.4-1.4-1.11.4-1.41.4-1.4
Latency to leave start box in cocaine runway0.30.40.8-0.90.9-0.60.6-0.70.90.70.70.60.40.40.4-0.4-0.5-0.50.50.0-0.60.2-0.50.6
Latency to leave start box in cocaine runway, F1.01.32.9-1.31.3-0.91.0-1.21.71.51.51.20.90.80.9-0.9-1.1-1.11.00.7-1.20.9-1.11.3
Latency to leave start box in cocaine runway, M0.20.20.40.3-0.30.2-0.30.3-0.6-0.6-0.6-0.4-0.3-0.3-0.30.30.30.3-0.3-0.50.4-0.50.4-0.5
Std. dev. time between licks in bursts0.10.30.50.7-0.70.6-0.60.6-0.6-0.5-0.5-0.5-0.5-0.5-0.50.50.50.5-0.50.30.5-0.10.5-0.4
Total sessions with >9 infusions1.01.32.51.0-1.01.0-1.01.2-1.5-1.6-1.6-1.2-1.0-1.0-1.01.00.80.8-1.0-1.21.2-1.11.1-1.3
Short access day 1 total inactive lever presses0.00.10.30.3-0.30.5-0.30.3-0.4-0.5-0.5-0.3-0.2-0.2-0.20.20.10.1-0.20.10.3-0.10.2-0.3
Short access day 10 total inactive lever presses0.00.11.0-1.01.0-0.40.4-0.4-0.00.10.10.20.20.10.1-0.1-0.2-0.20.2-0.30.00.10.0-0.3
Short access day 1 total infusions0.50.92.00.0-0.00.5-0.70.8-1.2-1.3-1.3-0.9-0.9-0.9-0.90.90.80.8-0.9-1.41.1-0.81.0-1.3
Short access day 10 total infusions1.11.94.01.0-1.01.0-1.11.4-2.0-1.8-1.8-1.4-1.0-1.1-1.11.11.11.1-1.2-1.71.4-1.51.3-1.7
Short access total infusions0.60.82.00.4-0.40.4-0.60.8-1.2-1.2-1.2-0.8-0.8-0.8-0.80.80.70.7-0.9-1.41.0-1.00.9-1.2
Short access day 1 locomotion0.20.31.7-0.60.6-0.10.00.2-0.9-0.8-0.8-0.4-0.2-0.2-0.20.20.00.0-0.2-1.30.6-0.50.5-1.0
Short access day 10 total locomotion0.10.21.2-0.60.60.0-0.10.3-0.7-0.5-0.5-0.4-0.2-0.2-0.20.20.20.2-0.2-1.10.6-0.50.5-0.9
Short access total locomotion0.40.52.8-0.70.70.0-0.10.4-1.0-0.9-0.9-0.6-0.4-0.4-0.40.40.30.3-0.4-1.70.8-0.70.8-1.3
One hour access (0.3 mA shock)2.32.73.61.9-1.91.6-1.61.7-1.8-1.9-1.9-1.6-1.5-1.5-1.51.51.61.6-1.6-1.11.5-1.81.4-1.4
Compulsive drug intake0.71.02.80.2-0.2-0.30.6-0.71.31.31.30.90.80.90.9-0.9-0.9-0.90.91.7-1.10.9-1.11.4
One hour access (shock baseline)0.51.42.60.8-0.80.8-1.01.2-1.6-1.6-1.6-1.2-1.0-1.0-1.01.00.90.9-1.1-1.41.2-1.21.1-1.4
Social response proportion1.41.85.90.2-0.2-0.30.7-0.91.51.41.41.11.21.31.3-1.3-1.4-1.41.42.4-1.51.6-1.51.9
Social responses0.30.32.30.9-0.90.5-0.30.10.30.30.30.10.20.30.3-0.3-0.4-0.40.41.5-0.40.7-0.50.9
Social time0.20.42.60.9-0.90.7-0.50.20.80.40.40.0-0.1-0.1-0.10.1-0.1-0.10.11.6-0.30.8-0.31.0
Soleus weight0.41.26.02.4-2.41.4-0.90.80.20.20.2-0.20.30.20.3-0.3-0.1-0.10.12.4-0.50.7-0.61.3
Bone: stiffness0.40.72.90.3-0.3-0.10.4-0.50.80.60.60.70.91.01.0-1.0-0.8-0.80.81.7-1.01.0-1.01.2
Tibialis anterior weight4.415.330.25.5-5.55.5-5.04.7-3.6-3.5-3.5-4.1-3.8-3.8-3.83.83.73.7-3.70.33.3-2.43.2-2.0
Time to tail flick, vehicle, before self-admin1.82.25.92.4-2.42.2-2.01.8-1.2-1.1-1.1-1.5-1.5-1.4-1.41.41.31.3-1.20.31.1-1.01.0-0.4
Time to tail flick, vehicle, after self-admin0.10.20.50.4-0.40.5-0.40.30.0-0.3-0.3-0.3-0.4-0.4-0.40.40.70.7-0.60.40.20.10.20.0
Time to tail flick, test, before self-admin0.60.72.4-0.60.6-0.10.2-0.61.51.51.50.60.10.10.1-0.1-0.3-0.30.41.4-0.71.3-0.51.1
Time to tail flick, test, after self-admin0.50.50.7-0.50.5-0.80.8-0.80.80.60.60.80.70.70.7-0.7-0.7-0.70.70.8-0.80.7-0.70.8
Delta time to tail flick, vehicle, before/after SA0.20.21.8-1.31.3-0.60.5-0.50.30.00.00.2-0.0-0.1-0.10.10.20.2-0.2-0.40.00.30.1-0.2
Delta time to tail flick, test, before/after SA0.70.82.70.8-0.80.3-0.50.7-1.4-1.6-1.6-0.7-0.4-0.4-0.40.40.50.5-0.6-1.30.8-1.40.7-1.1
Tibia length1.95.37.1-1.41.4-2.02.3-2.42.62.32.32.52.62.32.3-2.3-2.3-2.32.32.7-2.62.3-2.62.7
Ambulatory time before self-admin0.72.04.5-1.91.9-2.11.9-1.71.11.01.01.51.51.51.4-1.4-1.3-1.31.40.3-1.11.3-1.10.4
Ambulatory time after self-admin0.91.52.5-0.80.8-1.11.2-1.11.11.01.01.21.31.41.3-1.3-1.5-1.51.61.0-1.21.3-1.21.1
Bone: tissue strength1.51.63.5-1.91.9-1.51.5-1.61.31.11.11.31.11.21.2-1.2-1.1-1.11.20.5-1.11.2-1.00.8
Total heroin consumption1.01.16.92.6-2.61.5-1.21.1-0.6-0.9-0.9-0.7-0.3-0.3-0.40.40.50.5-0.40.60.2-1.20.10.4
Bone: trabecular number1.73.211.03.3-3.32.4-2.22.1-1.5-1.6-1.6-1.7-1.4-1.6-1.61.61.51.5-1.60.61.2-1.11.1-0.5
Bone: trabecular spacing0.10.10.8-0.90.9-0.30.3-0.2-0.2-0.0-0.00.10.10.30.3-0.30.00.00.0-0.50.1-0.00.1-0.4
Bone: trabecular thickness0.10.10.30.5-0.50.5-0.40.3-0.1-0.1-0.1-0.2-0.3-0.3-0.30.30.20.2-0.20.40.10.10.10.2
Bone: trabecular tissue density0.61.02.6-1.61.6-1.61.3-1.20.80.80.81.00.81.00.9-0.9-1.0-1.00.9-0.6-0.70.3-0.60.3
Water consumed over 24 hours1.32.63.5-1.31.3-1.51.6-1.61.91.71.71.71.61.81.8-1.8-1.7-1.71.71.0-1.71.3-1.61.6
Number of responses in last shaping day0.50.61.8-0.30.30.1-0.20.4-1.1-1.2-1.2-0.6-0.5-0.5-0.60.60.40.4-0.6-1.30.9-0.80.8-1.3