Ube2u

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	RMTg	isoform ratio	XM_063261314.1	0.1	0.07	9.9e-03	0.1	0.08	0.04	0.09	1.4e-03	4.5e-03	3.4e-02	2.9e-03
2	RMTg	intron excision ratio	chr5_120237842_120244009	0.13	0.1	7.1e-03	0.02	-0	-0.01	-0	1.1e-01	4.0e-01	6.8e-01	3.9e-01
3	Brain	gene expression	Ube2u	0.06	0.04	2.1e-05	0.06	0.06	0.06	0.05	2.9e-06	7.6e-06	5.4e-06	8.1e-06
4	pVTA	intron excision ratio	chr5_120234397_120237750	0.04	0.03	5.7e-03	0.03	0.02	0.02	0.02	1.8e-03	1.5e-02	1.5e-02	5.4e-03
5	Brain	intron excision ratio	chr5_120234397_120237750	0.07	0.05	1.9e-04	0.03	0.03	0.03	0.03	4.2e-04	2.0e-03	1.4e-03	7.5e-04
6	BLA	gene expression	Ube2u	0.09	0.08	1.0e-02	0.05	0.01	0.04	0.03	1.7e-03	7.7e-02	4.4e-03	8.9e-03
7	IL	isoform ratio	XM_006238443.5	0.16	0.1	5.8e-03	0.06	0.03	0	0.02	1.6e-02	5.5e-02	2.7e-01	8.9e-02
8	BLA	isoform ratio	XM_063261314.1	0.12	0.08	1.8e-03	0.05	0.02	0.04	0.03	9.6e-04	3.4e-02	5.8e-03	8.5e-03
9	NAcc	gene expression	Ube2u	0.11	0.04	0.0e+00	0.1	0.13	0.13	0.13	9.9e-15	1.4e-18	1.7e-18	3.7e-19
10	RMTg	alternative TSS	XM_063261314.1	0.2	0.14	9.9e-03	0.04	0.04	-0.01	0.03	3.4e-02	2.7e-02	6.1e-01	5.1e-02
11	PL	gene expression	Ube2u	0.1	0.04	3.8e-10	0.06	0.08	0.07	0.07	9.8e-07	2.1e-09	1.5e-08	5.2e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	0.3	0.6	1.4	0.8	-0.9	0.7	-1.2	-1.1	0.7	0.8	-0.4	-0.8	0.2	0.1
Area under the delay curve	2.0	2.4	6.0	2.4	-2.3	2.2	-0.9	-0.5	1.9	0.3	-1.3	-1.5	0.9	0.6
BMI with tail	0.7	2.4	4.2	-1.7	1.3	-2.0	1.7	1.7	-2.1	-1.3	1.2	0.0	-1.1	-1.8
BMI without tail	1.0	3.1	6.0	-2.0	1.9	-2.4	1.9	2.0	-2.4	-1.6	1.1	1.0	-0.8	-1.3
Body weight	0.5	2.2	3.8	-1.7	1.6	-1.7	1.8	1.8	-1.8	-0.5	1.0	-0.3	-1.1	-2.0
Weight adjusted by age	0.3	0.4	1.8	0.5	-0.6	0.3	0.7	0.2	0.2	-0.6	-1.1	0.2	1.4	0.4
Bone surface	1.3	2.4	4.0	-2.0	1.9	-1.9	1.4	1.4	-1.8	-1.3	1.5	0.8	-1.3	-1.3
Bone volume	0.1	0.1	0.3	-0.5	0.4	-0.5	0.4	0.4	-0.5	-0.2	0.2	-0.1	-0.2	-0.5
Breakpoint value in progressive ratio session	0.5	0.6	2.4	-0.5	0.5	-0.4	-0.1	0.3	-0.6	0.5	1.1	-0.7	-1.5	-1.2
Number of licking bursts	0.1	0.1	0.5	0.4	-0.3	-0.0	0.6	0.6	-0.0	-0.7	0.3	-0.0	-0.4	-0.1
Context. condit. distance diff. score	1.0	1.2	5.7	0.4	-0.3	0.6	-1.0	-1.0	0.4	1.5	-0.1	-2.4	-0.7	-1.2
Locomotion velocity, session 1	1.3	1.4	4.4	-1.2	1.5	-0.9	0.9	1.0	-0.8	-0.9	2.1	0.8	-1.5	-0.8
Locomotion distance, session 1	0.2	0.2	0.7	0.2	0.0	0.8	-0.6	-0.4	0.8	0.5	0.3	-0.1	-0.3	0.2
Locomotion velocity, session 2	0.2	0.2	0.7	0.2	-0.2	0.3	-0.6	-0.7	0.4	-0.0	0.3	0.6	-0.1	0.9
Locomotion distance, session 2	0.7	0.9	2.2	-1.2	1.2	-0.6	0.3	0.3	-0.6	-1.1	1.4	1.5	-0.9	0.2
Locomotion velocity, session 3	0.1	0.1	0.5	0.2	-0.1	0.3	-0.1	-0.1	0.4	-0.0	-0.5	0.1	0.7	0.4
Locomotion distance, session 3	0.0	0.0	0.1	0.3	-0.1	0.1	0.3	0.3	0.2	0.1	-0.2	-0.3	0.1	-0.1
Stereotopy head waving bouts, day 3	1.5	1.8	2.6	1.1	-1.1	1.6	-1.4	-1.3	1.6	1.4	-1.6	-0.4	1.5	1.1
Stereotopy head waving duration, day 3	1.5	1.8	2.6	1.2	-1.2	1.5	-1.5	-1.4	1.5	1.0	-1.5	-0.3	1.6	1.3
Locomotion velocity, session 7	0.6	0.6	1.7	0.7	-0.5	0.9	-1.3	-1.2	0.9	0.8	-0.1	-0.5	-0.1	0.5
Locomotion distance, session 7	0.4	0.5	1.2	0.4	-0.1	0.7	-1.1	-1.0	0.8	0.8	0.6	-0.5	-1.0	0.0
Stereotopy head waving bouts, day 7	0.4	0.4	1.2	-0.5	0.5	-0.6	1.1	1.0	-0.6	-0.9	0.2	0.6	0.5	-0.1
Stereotopy head waving duration, day 7	0.8	0.9	2.2	-0.7	0.6	-0.9	1.3	1.3	-0.9	-1.5	0.5	1.1	0.6	0.1
Locomotion velocity, session 8	0.1	0.2	0.6	-0.2	0.3	-0.1	-0.0	0.1	-0.2	-0.1	0.8	-0.4	-0.7	-0.4
Locomotion distance, session 8	0.2	0.3	0.8	-0.4	0.5	0.3	-0.8	-0.8	0.2	0.4	0.7	-0.3	-0.9	-0.2
Degree of sensitization distance	0.3	0.4	1.8	-0.5	0.4	-0.2	-0.3	-0.1	-0.2	0.2	1.0	-0.1	-1.4	-0.6
Degree of sensitization stereotypy	0.9	1.0	2.3	-0.8	0.6	-1.1	1.5	1.4	-1.1	-1.4	0.2	0.9	0.6	-0.0
Conditioned locomotion	0.1	0.1	0.4	-0.0	0.1	0.1	0.5	0.7	-0.1	-0.4	0.1	-0.1	-0.1	-0.1
Cocaine response after cond. corrected	0.4	0.5	1.3	-0.2	0.3	-0.7	1.1	1.1	-0.4	-1.1	0.4	0.7	-0.1	0.0
Cocaine response after cond. not corrected	0.6	0.7	1.3	-0.6	0.7	-0.9	1.1	1.1	-0.6	-0.9	0.9	0.8	-0.7	-0.2
Cocaine response before conditioning	0.3	0.4	1.1	-0.9	0.8	-0.3	-0.1	-0.4	-0.4	0.3	1.0	0.6	-1.0	-0.2
Saline control response	0.1	0.1	0.2	-0.2	0.0	-0.3	0.3	0.3	-0.3	-0.3	0.0	0.4	0.0	0.3
Bone: connectivity density	1.1	1.7	2.6	-1.5	1.3	-1.6	1.1	1.1	-1.6	-1.5	1.4	1.0	-1.0	-0.9
Bone: cortical apparent density	3.2	4.3	9.1	2.2	-2.1	2.5	-3.0	-3.0	2.3	1.7	-1.2	-1.1	0.7	1.6
Bone: cortical area	0.6	1.0	2.0	-1.2	1.2	-1.2	0.6	0.6	-1.0	-1.3	-0.5	1.4	0.7	0.3
Bone: cortical porosity	0.8	0.9	2.9	-1.0	0.8	-1.7	0.8	1.0	-1.6	-0.8	0.1	0.4	0.2	-0.6
Bone: cortical porosity	1.2	1.3	3.3	-1.0	0.9	-1.8	1.2	1.4	-1.8	-1.0	0.4	0.4	-0.2	-0.9
Bone: cortical thickness	0.2	0.4	2.2	-0.1	0.1	-0.1	-0.0	-0.2	-0.2	-0.1	-1.5	0.0	1.3	0.2
Bone: cortical thickness	0.1	0.1	0.2	-0.4	0.4	0.0	-0.1	-0.1	-0.1	0.4	-0.4	-0.3	-0.0	-0.5
Bone: cortical tissue density	3.1	4.2	8.9	2.2	-2.0	2.5	-3.0	-2.9	2.3	1.7	-1.1	-1.1	0.6	1.5
Condit. Reinf. active minus inactive responses	1.0	1.1	2.3	-1.5	1.3	-1.1	0.7	0.7	-1.0	-1.3	0.7	1.5	-0.7	-0.2
Condit. Reinf. active-inactive response ratio	1.0	1.0	2.0	-1.4	1.2	-1.4	0.7	0.8	-1.2	-1.2	0.4	1.1	-0.5	-0.4
Condit. Reinf. active responses	1.5	1.9	3.6	-1.9	1.6	-1.4	1.3	1.3	-1.3	-1.7	0.9	1.9	-0.5	-0.2
Condit. Reinf. inactive responses	0.6	0.7	1.1	-0.9	0.9	-0.6	1.0	1.0	-0.6	-1.0	1.1	1.1	-0.5	-0.2
Incentive salience index mean	1.8	2.2	5.2	-2.3	2.0	-1.5	0.9	0.9	-1.4	-1.7	1.0	2.1	-0.8	-0.2
Condit. Reinf. lever presses	1.5	2.1	5.7	-2.4	2.2	-1.4	0.8	0.7	-1.2	-1.2	1.4	1.7	-1.2	-0.5
Condit. Reinf. active minus inactive responses	0.3	0.4	1.2	-0.3	0.4	0.4	-1.0	-1.0	0.6	1.1	0.3	-0.0	-0.5	-0.0
Condit. Reinf. active-inactive response ratio	0.3	0.3	1.0	-0.6	0.7	-0.3	-0.5	-0.4	-0.1	0.2	1.0	0.7	-0.9	0.1
Condit. Reinf. active responses	0.3	0.5	1.2	-0.7	0.9	0.0	-0.6	-0.8	0.2	1.1	0.8	-0.1	-1.0	-0.6
Condit. Reinf. inactive responses	0.5	0.7	2.2	0.5	-0.4	0.9	-1.0	-1.2	0.8	1.5	-0.6	-0.9	0.2	-0.1
Condit. Reinf. lever presses	3.2	4.4	9.8	-2.7	2.8	-1.8	1.6	1.4	-1.5	-1.5	3.1	2.2	-2.3	-0.9
Condit. Reinf. lever reinforcers received	0.3	0.5	1.2	-0.8	1.0	-0.1	-0.2	-0.5	0.0	0.8	1.0	0.1	-1.1	-0.6
Conditioned reinforcement - actives	0.1	0.2	0.7	-0.5	0.4	-0.5	0.2	0.1	-0.4	-0.6	0.4	0.8	-0.3	0.1
Conditioned reinforcement - inactives	0.3	0.4	1.6	-0.2	0.4	-0.1	0.1	0.3	-0.1	0.7	0.4	-1.2	-0.7	-1.1
Conditioned locomotion	0.3	0.4	0.8	-0.8	0.4	-0.9	0.6	0.8	-0.9	-0.7	0.5	0.6	-0.5	-0.3
Patch foraging indifference point 0 sec	5.0	9.3	19.0	-2.8	3.2	-2.9	4.4	4.2	-3.0	-2.5	3.0	1.1	-2.5	-2.6
Patch foraging indifference point AUC	1.0	1.5	2.8	-1.1	1.1	-1.1	1.2	1.1	-1.0	-1.6	1.6	1.7	-0.8	0.0
Delay disc. indifference point, 0s delay	3.3	3.7	9.4	2.7	-2.6	2.3	-1.5	-1.1	1.9	1.8	-1.0	-3.1	0.1	-0.4
Delay disc. indifference point, 16s delay	0.6	0.6	3.0	0.1	0.2	-0.0	1.2	1.4	-0.1	-1.7	-0.0	0.5	0.3	0.0
Delay disc. indifference point, 2s delay	2.0	2.2	6.4	2.1	-1.9	1.9	-0.7	-0.5	1.9	1.1	-0.9	-2.5	0.3	-0.4
Delay disc. indifference point, 24s delay	0.3	0.3	0.6	0.7	-0.7	0.8	-0.1	0.3	0.7	-0.6	-0.3	0.3	0.4	0.7
Delay disc. indifference point, 4s delay	5.1	5.4	10.8	3.3	-3.1	3.1	-2.2	-2.0	2.5	1.4	-2.1	-2.3	1.4	1.1
Delay disc. indifference point, 8s delay	2.1	2.5	5.4	2.3	-2.2	2.2	-1.5	-1.0	2.0	0.8	-1.1	-1.0	0.7	1.0
Indifference point function ln k	0.4	0.7	1.8	0.3	-0.5	0.6	-1.2	-0.9	0.5	1.4	-1.0	-1.1	0.1	-0.3
Indifference point function log k	0.4	0.7	1.8	0.3	-0.5	0.6	-1.2	-0.9	0.5	1.4	-1.0	-1.1	0.1	-0.3
Patch foraging total patch changes 0 sec	4.9	9.2	18.2	-2.8	3.2	-2.8	4.3	4.1	-3.0	-2.5	3.2	1.1	-2.7	-2.6
Patch foraging total patch changes 12 sec	1.3	1.7	4.1	-0.8	1.2	-0.7	2.0	2.0	-0.9	-1.4	1.6	0.9	-1.1	-0.7
Patch foraging total patch changes 18 sec	3.8	5.8	8.0	-2.4	2.7	-2.4	2.8	2.7	-2.6	-2.2	2.8	1.1	-2.3	-2.0
Patch foraging total patch changes 24 sec	1.7	2.9	5.6	-1.6	1.8	-1.7	2.3	2.4	-1.9	-1.3	1.5	0.2	-1.3	-1.7
Patch foraging total patch changes 6 sec	3.5	5.4	11.3	-2.1	2.4	-2.4	3.4	3.2	-2.5	-2.5	2.0	1.7	-1.1	-1.3
Patch foraging time to switch 0 sec	1.1	2.3	4.8	1.6	-1.6	1.4	-1.4	-1.2	1.3	0.4	-2.1	-0.0	2.2	1.8
Patch foraging water rate 0 sec	0.5	1.1	2.3	-1.0	1.3	-1.1	1.5	1.4	-1.1	-0.8	0.7	0.6	-0.8	-0.8
Patch foraging water rate 12 sec	2.8	5.8	8.8	-2.8	2.9	-2.9	2.3	2.2	-3.0	-1.6	2.2	0.8	-2.5	-2.4
Patch foraging water rate 18 sec	0.8	1.2	2.3	-0.8	1.1	-1.4	1.0	1.0	-1.5	-0.8	0.9	-0.2	-1.1	-1.4
Patch foraging water rate 24 sec	0.3	0.4	1.8	-0.3	0.7	-0.7	0.2	0.2	-0.8	0.1	0.1	-1.0	-0.7	-1.4
Patch foraging water rate 6 sec	0.1	0.2	0.5	-0.2	0.4	-0.0	-0.4	-0.4	0.0	0.7	0.1	-0.5	-0.5	-0.6
Seeking ratio, delayed vs. immediate footshock	1.5	1.8	5.6	-0.7	0.8	-1.0	0.3	0.5	-1.0	0.5	1.3	-2.0	-2.2	-2.4
Distance traveled before self-admin	0.8	1.0	2.3	-1.2	1.2	-1.1	0.8	1.5	-1.2	-0.7	0.5	-0.1	-0.7	-1.3
Distance traveled after self-admin	0.2	0.3	1.3	-0.3	0.4	-0.1	0.5	0.6	-0.3	-1.1	-0.2	0.8	0.4	0.2
Extensor digitorum longus weight	0.3	1.0	4.9	0.5	-0.4	0.5	-0.0	-0.3	0.2	0.9	-1.7	-2.2	0.8	-1.2
Bone: elastic displacement	0.3	0.4	0.9	0.3	-0.2	0.6	-0.6	-0.7	0.4	0.9	0.3	-1.0	-0.5	-0.6
Bone: elastic work	1.1	1.4	2.7	1.0	-1.0	1.2	-1.0	-1.1	1.1	1.5	-1.6	-1.4	1.2	0.1
Bone: endosteal estimation	0.9	2.0	3.6	-1.8	1.9	-1.7	1.0	1.1	-1.5	-0.6	1.6	0.7	-1.7	-1.2
Bone: endosteal perimeter	1.0	2.1	3.7	-1.7	1.7	-1.7	1.0	1.2	-1.6	-1.9	1.2	1.8	-0.7	-0.1
Epididymis fat weight	0.0	0.1	0.3	-0.5	0.5	-0.5	0.2	0.1	-0.4	-0.0	-0.1	0.2	-0.1	-0.1
Delta time in closed arm before/after self-admin	1.0	0.9	4.0	-0.1	0.2	-0.5	0.7	1.0	-0.5	0.0	1.6	-0.5	-2.0	-1.1
Delta time in open arm before/after self-admin	1.2	1.1	4.7	-1.0	1.0	-0.6	0.8	0.2	-0.5	-1.6	-0.3	2.2	1.0	1.1
Diff in mean of infusions in LGA sessions	1.2	1.5	3.3	-1.0	1.1	-1.3	1.1	1.0	-1.5	-0.3	1.7	0.1	-1.8	-1.2
Delay discount exponential model param	2.1	2.3	5.8	-2.4	2.2	-2.2	0.9	0.5	-1.8	-0.2	1.4	1.4	-1.0	-0.7
Extinction: sum of active levers before priming	0.6	0.6	3.1	0.5	-0.5	0.2	-0.3	-0.3	0.1	1.1	0.1	-1.8	-0.8	-1.0
Active lever presses in extinction session 6	1.5	1.5	3.1	-1.1	1.3	-1.3	0.8	1.1	-1.6	-0.4	1.4	-0.4	-1.6	-1.8
Bone: final force	0.2	0.3	1.0	-0.3	0.4	-0.4	-0.4	-0.4	-0.2	-0.0	-1.0	0.4	1.0	0.6
Bone: final moment	0.3	0.5	1.1	-1.0	1.0	-1.0	0.3	0.2	-0.8	-0.5	-0.6	0.7	0.6	0.1
Food consumed during 24 hour testing period	0.3	0.5	1.6	0.0	-0.3	0.5	-0.8	-0.8	0.5	0.4	0.2	1.2	-0.1	1.2
Glucose	0.4	0.7	1.6	-0.9	0.8	-1.2	0.3	0.5	-1.2	-0.7	0.9	0.2	-0.8	-0.9
Heart weight	0.6	0.9	3.1	0.1	-0.5	0.1	-1.1	-1.0	0.2	1.8	-0.9	-1.7	0.1	-0.7
Delay discount hyperbolic model param	2.6	2.8	6.9	-2.6	2.5	-2.4	1.0	0.7	-2.0	-0.3	1.5	1.6	-1.2	-0.8
Intermittent access intake day 1-15 change	0.6	1.3	3.7	0.9	-1.1	0.7	-0.4	-0.5	0.8	-0.7	-1.5	0.9	1.9	1.7
Intermittent access intake escalation	1.2	2.5	6.3	1.6	-1.7	1.5	-0.7	-1.0	1.3	-0.3	-2.2	0.5	2.5	2.1
Intermittent access intake escalation 2	0.5	0.6	2.0	0.5	-0.6	0.5	-0.3	-0.3	0.6	-0.6	-1.0	0.7	1.4	1.2
Intermitt. access day 1 inactive lever presses	0.3	1.3	5.3	-0.8	0.6	-0.8	0.4	0.7	-1.1	0.4	0.6	-1.8	-1.1	-2.3
Intermitt. access day 15 inactive lever presses	0.3	0.7	1.9	-0.2	-0.1	-0.0	-1.1	-1.1	-0.0	1.4	0.4	-1.1	-1.1	-0.6
Intermitt. access escalation Index	2.8	3.9	6.2	2.3	-2.0	2.5	-2.0	-2.3	2.1	1.1	-2.0	-0.2	2.1	2.1
Intermittent access day 1 total infusions	0.1	0.2	0.8	0.4	-0.1	0.1	-0.9	-0.7	-0.1	0.8	-0.0	-0.6	-0.3	-0.1
Intermittent access day 15 total infusions	1.3	1.9	3.6	1.7	-1.6	1.4	-1.0	-1.1	1.1	0.3	-1.9	0.0	1.9	1.7
Intermittent access terminal intake (last 3 days)	0.2	0.3	0.7	0.7	-0.7	0.4	-0.5	-0.5	0.3	0.0	-0.7	0.1	0.8	0.7
Intermittent access total infusions	0.4	0.5	1.2	1.0	-0.9	0.6	-0.6	-0.6	0.4	0.4	-1.1	-0.2	0.9	0.7
Intermittent access day 1 locomotion	0.2	0.2	1.2	-0.5	0.4	-0.5	0.1	0.1	-0.6	-0.5	0.1	1.1	0.0	0.4
Intermittent access day 15 total locomotion	0.5	0.9	3.2	-0.9	0.7	-1.0	0.1	0.4	-1.1	-1.5	-0.2	1.8	0.7	0.9
Intermittent access total locomotion	0.4	0.5	1.6	-0.7	0.6	-0.8	0.2	0.3	-0.9	-1.0	-0.3	1.2	0.5	0.5
Intermittent access standard deviation	0.1	0.1	0.4	0.2	-0.7	-0.3	-0.4	-0.2	-0.1	-0.1	-0.5	0.4	0.4	0.5
Left kidney weight	0.1	0.4	0.7	-0.8	0.7	-0.7	0.5	0.4	-0.7	0.3	-0.5	-0.6	0.4	-0.8
Right kidney weight	0.1	0.6	1.9	-0.4	0.2	-0.1	-0.5	-0.5	0.0	1.3	-1.4	-1.2	1.0	-0.6
Cocaine induced anxiety	2.7	3.8	8.7	1.9	-1.6	1.9	-0.1	-1.5	2.0	-0.2	-2.7	1.4	2.9	3.0
Post-drug Anxiety	5.0	5.4	10.7	2.6	-2.3	2.5	-1.0	-2.1	2.6	1.2	-3.3	-0.1	3.1	2.5
Baseline Anxiety	0.6	0.7	2.8	0.4	-0.4	0.4	-1.1	-0.3	0.4	1.4	-0.4	-1.7	0.1	-0.8
Tail length	0.0	0.1	0.4	-0.3	0.6	-0.1	0.2	0.1	0.0	0.6	-0.6	0.1	0.2	0.1
Length with tail	0.1	0.3	0.7	-0.5	0.8	-0.2	0.8	0.7	-0.3	0.6	-0.1	-0.5	-0.2	-0.7
Length without tail	0.3	0.9	3.1	-0.6	0.7	-0.6	1.1	1.2	-0.7	0.2	0.0	-1.2	-0.4	-1.8
Times rat made contact with spout	0.9	1.0	1.5	-1.2	1.1	-1.2	0.9	0.9	-1.2	-0.7	1.2	0.5	-1.0	-0.9
Lifetime Intake	0.7	0.9	1.8	1.2	-1.1	0.8	-0.5	-0.8	0.7	0.5	-1.3	-0.1	1.3	1.1
Liver weight, left	1.1	1.8	4.0	1.3	-1.4	1.0	-1.9	-1.8	0.9	1.7	-0.4	-2.0	-0.6	-0.2
Liver weight, right	0.7	1.3	6.6	0.5	-0.7	0.5	-0.5	-0.3	0.6	1.8	-0.5	-2.6	-0.6	-1.5
Locomotor activity	0.1	0.1	0.5	-0.2	0.2	-0.2	0.7	0.4	0.0	0.1	-0.5	-0.4	0.3	-0.4
Locomotor testing distance	0.9	1.6	4.1	-1.3	1.5	-1.5	2.0	1.7	-1.2	-0.7	0.7	0.4	-0.5	-1.0
Locomotor testing rearing	0.1	0.2	0.9	-0.2	0.4	-0.4	1.0	0.8	-0.3	-0.0	0.1	-0.0	-0.1	-0.3
Locomotion in novel chamber	1.6	2.1	3.7	-1.8	1.7	-1.9	1.0	1.9	-1.8	-1.7	0.5	0.9	-0.3	-0.8
Locomotion in novel chamber post-restriction	0.3	0.5	1.3	-0.1	0.1	0.7	-0.6	-0.2	0.4	-0.6	-1.0	1.1	1.0	1.2
Fecal boli incidents, locomotor time 1	0.3	0.4	1.1	0.5	-0.5	0.2	-0.0	-0.0	0.5	-0.4	-0.8	0.9	1.1	0.9
Change in fecal boli incidents, locomotor task	0.3	0.3	0.8	0.4	-0.5	0.5	-0.1	-0.5	0.6	0.8	-0.1	-0.9	-0.2	-0.2
Time >=10cm from walls, locomotor time 1	0.9	0.9	3.9	1.0	-0.7	0.7	0.1	0.2	0.6	-0.2	-1.9	-0.4	2.0	0.6
Bouts of movement, locomotor time 1	1.6	1.9	5.5	-0.7	0.8	-1.3	1.2	1.5	-1.8	-0.5	0.9	-1.5	-1.5	-2.4
Total resting periods, locomotor time 1	1.5	1.6	5.2	-0.5	0.7	-1.1	1.1	1.3	-1.5	-0.2	0.9	-1.5	-1.4	-2.3
Rest time, locomotor task time 1	0.3	0.4	1.2	-0.4	0.5	-0.5	0.2	0.2	-0.5	0.3	0.8	-0.7	-1.0	-1.1
Distance moved, locomotor task time 1	0.2	0.3	0.6	0.5	-0.2	0.4	-0.7	-0.5	0.8	0.6	0.5	0.2	-0.3	0.6
Vertical activity count, locomotor time 1	0.3	0.7	1.8	1.0	-0.6	0.6	-0.8	-0.5	0.9	0.5	-1.0	0.1	1.3	0.9
Time >=10cm from walls, locomotor time 2	1.3	1.9	4.0	1.2	-1.5	0.7	-1.3	-1.1	0.8	1.7	-2.0	-1.9	1.6	0.1
Bouts of movement, locomotor time 2	0.6	0.9	2.2	-1.0	0.8	-1.3	0.8	1.1	-1.4	-1.5	-0.2	0.1	0.3	-0.9
Total resting periods, locomotor time 2	0.4	0.7	1.9	-0.8	0.7	-1.0	0.9	1.1	-1.1	-1.4	-0.2	0.2	0.3	-0.7
Rest time, locomotor task time 2	0.1	0.1	0.4	0.5	-0.3	0.6	0.1	0.2	0.4	0.2	0.0	-0.3	-0.2	-0.2
Distance moved, locomotor task time 2	0.6	0.7	2.0	0.1	0.0	-0.2	-1.0	-1.2	0.3	1.4	0.9	-0.8	-1.1	-0.2
Vertical activity count, locomotor time 2	0.1	0.2	0.8	0.1	0.1	-0.4	-0.6	-0.5	0.2	0.9	-0.3	-0.6	0.3	-0.1
Light reinforcement 1	0.4	1.0	3.6	-1.0	1.4	-0.5	-0.3	-0.0	-0.3	0.4	1.6	-0.3	-1.9	-1.3
Light reinforcement 2	0.1	0.2	0.8	-0.2	0.3	0.3	-0.9	-0.6	0.4	0.6	-0.2	-0.5	-0.3	-0.4
Bone: marrow area	0.9	1.9	3.6	-1.8	1.9	-1.6	0.9	1.1	-1.5	-0.6	1.6	0.7	-1.8	-1.2
Bone: maximum diameter	0.6	1.0	2.6	-1.0	1.0	-1.2	0.8	0.9	-1.0	-1.5	-0.3	1.6	0.7	0.5
Bone: maximum force	0.3	0.5	1.4	-1.1	1.2	-1.1	0.3	0.2	-0.9	-0.6	-0.2	0.9	0.1	0.0
Bone: maximum moment	0.9	1.6	3.7	-1.9	1.9	-1.7	1.0	1.0	-1.5	-1.1	0.3	1.1	-0.3	-0.6
Mean time between licks in bursts	2.1	5.1	9.3	2.3	-2.3	2.7	-2.9	-2.5	2.5	3.1	-1.3	-2.6	0.1	0.3
Mean num. licks in bursts	0.3	0.5	1.7	-1.2	1.3	-0.8	0.1	0.2	-0.8	0.2	0.5	0.5	-0.2	-0.5
Cd content in liver	3.4	3.8	5.8	-2.3	2.4	-2.0	1.6	1.7	-2.0	-1.8	2.4	1.8	-2.0	-0.9
Co content in liver	2.3	2.7	7.0	-1.8	2.0	-1.3	0.9	0.8	-1.4	-0.2	1.9	-0.9	-2.6	-2.5
Cu content in liver	0.2	0.3	0.5	0.5	-0.3	0.6	-0.6	-0.5	0.5	0.7	-0.7	-0.7	0.4	0.1
Fe content in liver	2.2	2.7	9.9	-0.9	1.0	-1.2	0.6	1.1	-1.5	0.3	1.3	-2.3	-2.4	-3.1
K content in liver	1.1	1.1	2.4	0.8	-0.7	1.0	-1.5	-1.5	0.9	1.2	-1.1	-1.1	0.6	0.2
Mg content in liver	0.5	0.5	1.9	-0.2	0.2	-0.1	-0.2	-0.2	-0.2	-0.7	-0.8	1.2	1.4	1.1
Mn content in liver	0.3	0.4	0.8	-0.7	0.8	-0.6	0.4	0.6	-0.7	-0.9	-0.1	0.8	0.2	0.1
Na content in liver	1.4	1.5	5.6	0.5	-0.4	1.1	-2.4	-2.1	0.9	1.5	-0.5	-1.0	0.1	0.1
Rb content in liver	0.2	0.2	0.4	0.6	-0.5	0.7	-0.5	-0.4	0.6	0.4	-0.5	-0.5	0.2	0.0
Se content in liver	1.0	1.2	3.6	-0.8	1.0	-0.7	0.6	0.9	-0.8	0.0	1.2	-1.2	-1.6	-1.9
Sr content in liver	2.3	2.0	4.8	-1.6	1.5	-1.5	0.3	0.6	-1.5	-1.4	2.2	1.2	-2.0	-0.7
Zn content in liver	1.1	1.2	3.8	-1.2	1.3	-0.9	0.8	0.7	-1.0	-1.7	0.3	1.9	0.4	0.6
Bone: minimum diameter	0.8	1.4	2.7	-1.2	1.3	-1.7	1.3	1.4	-1.5	-1.5	-0.3	1.1	0.5	-0.3
Time in familiar zone, hab. session 1	1.0	1.0	2.9	1.1	-1.0	0.6	-0.9	-0.8	0.6	1.0	-1.4	-1.7	0.6	-0.3
Time in novel zone, hab. session 1	3.0	3.0	4.8	-1.8	1.8	-1.5	1.8	1.8	-1.6	-2.1	2.2	2.1	-1.1	-0.2
Total zone transitions, hab. session 1	1.2	1.6	3.2	1.1	-1.1	1.7	-0.9	-1.0	1.6	1.0	-1.8	-0.5	1.6	1.1
Total locomotion distance, hab. session 1	0.3	0.4	1.2	0.2	-0.2	0.8	-0.5	-0.6	1.0	1.1	-0.8	-0.4	0.6	0.3
Locomotion velocity, hab. session 1	0.5	0.6	1.5	0.4	-0.4	1.0	-0.5	-0.7	1.2	1.0	-1.1	-0.3	0.9	0.6
Time in familiar zone, hab. session 2	0.1	0.1	0.2	0.0	-0.0	-0.5	0.2	0.1	-0.5	-0.4	-0.5	-0.3	0.3	-0.2
Time in novel zone, hab. session 2	0.1	0.1	0.3	-0.2	0.3	0.1	0.3	0.4	-0.2	-0.3	0.6	0.5	-0.3	0.1
Total zone transitions, hab. session 2	3.9	5.0	8.5	2.3	-2.2	2.9	-2.7	-2.7	2.7	2.1	-1.6	-1.0	1.3	1.8
Total locomotion distance, hab. session 2	3.3	4.3	6.8	2.0	-1.8	2.6	-2.4	-2.4	2.6	2.2	-2.1	-1.1	1.7	1.5
Locomotion velocity, hab. session 2	3.2	4.3	6.7	2.0	-1.8	2.6	-2.4	-2.4	2.6	2.1	-2.1	-0.9	1.7	1.7
Novel to familiar place preference ratio	1.0	1.0	2.0	-1.4	1.2	-1.2	1.0	1.1	-1.2	-0.9	0.8	1.0	-0.1	-0.3
Novelty place preference	0.7	0.7	1.5	-1.2	1.0	-1.1	0.8	0.9	-1.2	-0.7	0.8	0.6	-0.3	-0.4
Time in novel zone, NPP test	1.0	1.1	2.0	-1.4	1.2	-1.3	0.9	1.0	-1.4	-0.8	1.0	0.6	-0.5	-0.7
Total zone transitions, NPP test	1.3	1.9	3.0	1.4	-1.3	1.7	-1.5	-1.4	1.7	1.0	-1.5	-0.6	1.4	1.2
Total locomotion distance, NPP test	1.1	1.6	2.7	1.1	-1.0	1.5	-1.3	-1.3	1.6	1.4	-1.4	-0.5	1.2	1.1
Locomotion velocity, NPP test	1.1	1.6	2.9	1.2	-1.0	1.6	-1.3	-1.3	1.7	1.3	-1.4	-0.4	1.3	1.2
Intraocular pressure	0.6	0.9	1.5	0.9	-0.8	1.2	-1.1	-1.1	1.2	0.3	-1.1	-0.1	0.8	1.0
Delta distance traveled before/after self-admin	0.6	0.6	1.4	0.6	-0.5	0.4	0.4	-0.3	0.5	-1.0	-0.7	1.0	1.2	1.2
Delta ambulatory time before/after self-admin	0.9	1.1	2.7	1.1	-1.0	0.8	-0.0	-0.8	0.9	-0.8	-0.9	1.0	1.5	1.6
Parametrial fat weight	4.5	10.6	16.3	-4.0	4.0	-3.8	3.4	3.6	-3.7	-3.3	2.8	2.4	-1.8	-1.9
Pavlov. Cond. lever latency	2.4	3.0	6.4	2.5	-2.5	1.6	-2.0	-1.8	1.5	1.4	-1.4	-1.2	1.2	1.4
Pavlov. Cond. magazine entry latency	0.2	0.2	0.8	-0.7	0.5	-0.2	0.6	0.5	-0.0	-0.4	-0.2	0.9	0.4	0.4
Pavlov. Cond. change in total contacts	1.9	2.1	4.2	-2.1	2.0	-1.5	1.4	1.3	-1.4	-1.4	1.1	1.6	-0.8	-0.6
Pavlov. Cond. index score	1.4	1.7	3.8	-1.9	1.8	-1.1	1.7	1.5	-1.0	-1.0	1.0	1.1	-0.8	-0.9
Pavlov. Cond. latency score	1.4	1.8	3.8	-1.9	1.8	-1.2	1.7	1.5	-1.1	-1.1	1.0	1.1	-0.8	-0.9
Pavlov. Cond. lever contacts	1.8	2.1	4.4	-2.1	2.1	-1.3	1.7	1.5	-1.3	-1.2	1.1	1.1	-1.0	-1.1
Pavlov. Cond. magazine entry number	0.2	0.2	0.6	0.6	-0.4	0.1	-0.6	-0.3	-0.0	0.4	0.3	-0.8	-0.3	-0.3
Pavlov. Cond. intertrial magazine entries	1.7	2.0	3.7	1.4	-1.4	1.6	-1.5	-1.4	1.7	0.9	-1.3	0.5	1.3	1.9
Pavlov. Cond. lever-magazine prob. diff.	1.4	1.7	3.8	-1.9	1.8	-1.0	1.7	1.5	-0.9	-1.1	0.9	1.2	-0.7	-0.8
Pavlov. Cond. response bias	0.9	1.1	3.0	-1.7	1.5	-0.9	1.3	1.1	-0.7	-0.9	0.5	1.1	-0.4	-0.5
Pavlov. Cond. lever latency	2.0	2.7	7.6	2.0	-2.0	1.0	-1.6	-1.3	0.7	1.7	-1.9	-2.8	0.9	-0.4
Pavlov. Cond. magazine entry latency	1.8	2.2	3.5	-1.6	1.5	-1.4	1.6	1.5	-1.3	-1.9	1.7	1.9	-1.0	-0.1
Pavlov. Cond. change in total contacts	1.1	1.7	4.7	-1.7	1.7	-0.9	1.2	1.0	-0.6	-1.4	1.5	2.2	-0.8	0.2
Pavlov. Cond. index score	1.7	2.3	4.1	-1.9	1.8	-1.3	1.5	1.3	-1.1	-1.5	1.8	2.0	-1.2	-0.2
Pavlov. Cond. latency score	1.6	2.1	3.7	-1.8	1.8	-1.2	1.4	1.3	-1.0	-1.4	1.9	1.8	-1.4	-0.3
Pavlov. Cond. lever contacts	2.0	2.7	8.1	-2.0	2.0	-1.0	1.5	1.2	-0.8	-1.8	2.0	2.8	-1.0	0.4
Pavlov. Cond. magazine entry number	0.6	0.8	2.0	0.9	-0.8	0.6	-1.0	-0.9	0.6	1.3	-0.7	-1.4	0.2	-0.3
Pavlov. Cond. intertrial magazine entries	1.8	2.8	5.1	2.0	-2.0	1.6	-1.5	-1.5	1.6	1.5	-2.3	-1.2	1.8	1.1
Pavlov. Cond. lever-magazine prob. diff.	1.7	2.2	4.0	-1.8	1.8	-1.3	1.4	1.3	-1.1	-1.5	1.8	2.0	-1.2	-0.2
Pavlov. Cond. response bias	1.7	2.3	7.1	-1.8	1.8	-1.0	1.5	1.2	-0.8	-1.8	1.6	2.7	-0.6	0.5
Time in closed arm before self-admin	1.3	1.6	5.0	0.8	-0.8	0.9	-1.0	-1.1	0.9	-0.3	-1.8	1.0	2.2	1.9
Time in closed arm after self-admin	0.2	0.2	0.7	0.8	-0.8	0.4	-0.0	0.1	0.3	0.3	0.1	-0.6	-0.3	0.1
Time in open arm before self-admin	1.5	1.7	4.4	-0.6	0.5	-0.9	1.2	1.2	-1.0	0.1	1.7	-1.3	-2.0	-2.1
Time in open arm after self-admin	1.5	1.6	3.4	-1.7	1.6	-1.4	1.8	1.0	-1.3	-1.4	0.4	1.5	0.2	-0.4
Bone: periosteal estimation	0.8	1.7	3.6	-1.9	1.9	-1.7	1.0	1.1	-1.6	-1.1	0.6	1.2	-0.6	-0.6
Bone: periosteal perimeter	1.0	1.8	3.8	-1.5	1.6	-1.6	0.8	0.9	-1.5	-1.9	0.7	2.0	-0.2	0.2
Bone: post-yield work	2.6	3.8	7.6	-2.6	2.8	-2.3	1.4	1.4	-2.0	-2.1	1.6	2.0	-1.4	-0.6
Progressive ratio test 1 active lever presses	1.2	1.5	2.7	1.5	-1.5	1.4	-1.4	-1.6	1.4	0.8	-0.6	-0.1	0.5	1.1
Progressive ratio test 1 breakpoint	1.4	1.7	3.2	1.6	-1.6	1.5	-1.5	-1.8	1.6	1.0	-0.6	-0.2	0.5	1.2
Progressive ratio test 1 inactive lever presses	0.9	1.3	2.9	1.4	-1.2	1.1	-1.5	-1.7	1.1	1.1	-1.0	-0.8	0.5	0.7
Progressive ratio test 2 active lever presses	0.2	0.2	0.8	0.3	-0.3	0.4	-0.3	-0.3	0.2	-0.6	-0.1	0.9	0.3	0.9
Progressive ratio test 2 breakpoint	0.3	0.3	1.0	0.5	-0.5	0.5	-0.5	-0.4	0.4	-0.5	-0.3	0.9	0.5	1.0
Progressive ratio test 2 inactive lever presses	0.0	0.1	0.2	0.3	-0.2	0.4	-0.3	-0.3	0.1	-0.1	-0.2	0.2	0.1	0.3
Incentive Sensitization - Responses	0.2	0.3	1.2	-0.4	0.3	-0.2	-0.0	0.1	-0.3	-1.0	-0.4	1.1	0.6	0.8
Incentive Sensitization - Breakpoint	0.3	0.4	1.5	-0.4	0.3	-0.3	0.1	0.3	-0.4	-1.1	-0.4	1.2	0.7	0.8
Sum of active levers in priming session hrs 5-6	2.9	2.7	8.6	-0.4	0.3	-0.2	-0.5	0.1	-0.3	1.5	1.8	-2.6	-2.9	-2.7
Progressive ratio	0.2	0.3	1.3	0.6	-0.5	0.5	-0.3	-0.3	0.8	-0.1	-0.2	0.6	0.3	1.1
Food seeking constrained by brief footshock	2.1	2.6	6.4	1.3	-1.4	1.7	-2.0	-2.1	2.0	2.5	0.3	-1.4	-1.0	0.4
Seeking ratio, punishment vs. effort	0.4	0.6	1.7	-0.1	-0.1	0.3	-0.9	-1.0	0.2	1.3	0.3	-1.2	-0.8	-0.8
Retroperitoneal fat weight	0.3	1.2	2.9	-1.1	1.5	-1.2	1.4	1.7	-1.2	-0.9	0.3	0.4	-0.1	-0.8
Reaction time number correct	0.3	0.6	1.9	0.3	-0.3	0.8	-1.0	-1.2	0.8	0.4	0.0	1.0	0.2	1.4
Reaction time mean minus median	0.6	1.6	3.2	-1.2	1.0	-1.3	1.2	1.1	-1.2	-1.8	1.6	1.6	-1.0	-0.1
Reaction time mean minus median AUC	0.2	0.6	1.3	-0.7	0.4	-0.7	0.4	0.4	-0.6	-1.1	1.1	1.2	-0.6	0.2
Reaction time num false alarms	0.1	0.1	0.6	-0.2	0.1	0.1	0.4	0.1	0.4	0.0	0.5	0.8	-0.3	0.3
Reaction time num false alarms AUC	0.4	0.6	1.8	-0.9	0.8	-0.4	0.9	0.6	-0.1	-0.5	1.0	1.3	-0.6	0.1
Reaction time trials correct on left	0.3	0.6	1.9	0.3	-0.3	0.8	-1.0	-1.2	0.8	0.4	0.0	1.0	0.2	1.4
Reaction time trials on left	0.3	0.5	1.8	0.2	-0.2	0.7	-0.9	-1.1	0.7	0.3	0.1	1.1	0.1	1.3
Reaction time mean	0.4	0.7	1.9	-0.6	0.2	-0.8	1.0	1.1	-1.0	-1.4	0.8	0.6	-0.4	-0.4
Reaction time mean AUC	0.3	0.4	1.1	-0.4	-0.0	-0.7	0.7	0.9	-0.8	-1.0	0.7	0.2	-0.5	-0.5
Median of all reaction times	0.2	0.3	1.2	-0.2	-0.1	-0.5	0.7	0.9	-0.7	-1.1	0.4	0.3	-0.2	-0.3
Reaction time omissions	1.4	2.1	3.4	-1.5	1.3	-1.4	1.4	1.4	-1.5	-1.8	1.8	1.5	-1.3	-0.5
Reaction time false alarm rate	0.6	0.8	1.9	-1.0	0.9	-0.9	1.4	1.1	-0.6	-0.7	0.9	0.9	-0.5	-0.5
Reaction time premature initiation rate	0.1	0.2	0.8	0.2	-0.1	-0.0	-0.3	-0.2	0.1	0.5	0.1	-0.9	-0.5	-0.7
Reaction time premature initiations	0.2	0.3	0.8	0.4	-0.3	0.5	-0.9	-0.9	0.6	0.8	-0.0	-0.5	-0.3	0.1
Std. dev. reaction times	1.7	3.1	5.0	-1.8	1.4	-1.8	1.9	1.9	-2.0	-2.2	2.1	1.4	-1.5	-1.0
Reaction time trials completed	0.3	0.5	1.8	0.2	-0.2	0.7	-0.9	-1.1	0.7	0.3	0.1	1.1	0.1	1.3
Reaction time trials AUC	0.3	0.6	1.9	0.2	-0.2	0.7	-0.8	-1.0	0.7	0.3	0.0	1.1	0.3	1.4
Run reversals in cocaine runway, females	0.4	0.4	2.3	-0.1	-0.0	-0.2	0.3	0.3	-0.5	0.4	0.3	-1.5	-0.5	-1.2
Run reversals in cocaine runway, males	1.2	1.2	2.5	-1.5	1.6	-0.8	1.5	1.1	-0.7	-1.3	0.7	0.5	-0.8	-0.7
Latency to leave start box in cocaine runway	0.4	0.5	1.9	-0.5	0.4	0.1	-0.8	-0.8	0.0	0.8	1.0	-0.2	-1.4	-0.5
Latency to leave start box in cocaine runway, F	0.4	0.5	1.4	-0.8	0.7	-0.5	0.1	-0.0	-0.6	-0.2	1.2	0.7	-1.1	-0.2
Latency to leave start box in cocaine runway, M	0.8	0.7	2.0	0.1	-0.2	0.6	-0.9	-0.8	0.6	1.3	0.2	-1.4	-0.9	-0.8
Std. dev. time between licks in bursts	0.6	0.9	3.5	0.3	-0.3	0.6	-0.1	0.2	0.3	0.8	0.7	-1.9	-1.4	-1.5
Total sessions with >9 infusions	1.1	1.3	2.4	1.5	-1.5	1.1	-0.2	-0.8	1.2	0.8	-1.4	-0.4	1.4	1.2
Short access day 1 total inactive lever presses	0.2	0.3	1.1	-0.2	0.4	-0.4	0.5	-0.1	-0.4	0.2	0.0	-0.9	-0.3	-1.1
Short access day 10 total inactive lever presses	1.3	3.0	7.5	-1.9	1.8	-1.9	1.5	1.6	-2.0	0.0	1.4	-1.3	-1.8	-2.7
Short access day 1 total infusions	0.6	0.8	1.6	1.3	-1.2	0.9	-0.4	-1.0	1.0	1.0	-0.8	-0.7	0.6	0.5
Short access day 10 total infusions	0.0	0.0	0.1	0.3	-0.3	-0.2	0.0	0.0	-0.2	0.2	-0.3	-0.1	0.1	0.1
Short access total infusions	0.3	0.4	0.9	0.9	-0.9	0.5	-0.0	-0.6	0.5	0.3	-0.8	0.0	0.8	0.8
Short access day 1 locomotion	0.1	0.2	0.6	-0.3	-0.3	-0.4	0.6	-0.2	-0.2	-0.2	-0.1	0.8	0.3	0.5
Short access day 10 total locomotion	1.0	1.8	4.5	-1.7	1.1	-2.1	1.4	1.6	-1.9	-1.2	0.5	1.0	-0.4	-0.7
Short access total locomotion	0.2	0.2	0.8	0.0	-0.5	-0.3	0.5	0.0	-0.1	-0.2	-0.4	0.9	0.5	0.8
One hour access (0.3 mA shock)	1.0	1.2	4.2	-0.9	0.6	-0.8	0.2	0.4	-0.8	-1.8	-0.6	2.1	1.1	1.0
Compulsive drug intake	0.9	1.1	2.5	-1.2	1.0	-0.9	1.5	1.0	-1.0	-1.6	-0.4	1.1	0.8	-0.2
One hour access (shock baseline)	0.5	0.8	1.5	1.0	-1.0	0.6	-1.1	-0.8	0.5	0.1	-1.2	0.1	1.2	1.1
Social response proportion	0.3	0.4	1.7	-0.0	0.2	-0.1	0.0	0.1	-0.3	-1.1	-0.1	1.3	0.4	1.0
Social responses	0.5	0.7	3.1	-0.4	0.7	-0.2	0.3	0.2	-0.3	-0.5	1.6	0.4	-1.8	-0.4
Social time	0.5	0.6	1.3	-0.6	0.8	-0.5	0.7	0.5	-0.4	-1.1	1.1	1.0	-1.1	-0.0
Soleus weight	0.1	0.4	1.3	-0.9	0.9	-0.4	-0.2	-0.1	-0.4	-0.6	0.5	1.1	-0.2	0.5
Bone: stiffness	0.3	0.4	1.4	-0.9	0.9	-1.2	0.2	0.2	-0.9	-0.7	-0.3	0.6	0.2	0.0
Tibialis anterior weight	5.3	17.9	30.5	-4.7	4.7	-4.6	5.5	5.2	-4.9	-4.9	2.7	3.1	-1.2	-2.5
Time to tail flick, vehicle, before self-admin	1.4	1.4	3.4	-1.1	1.1	-1.3	1.4	1.8	-1.5	-1.6	0.2	0.6	0.2	-0.7
Time to tail flick, vehicle, after self-admin	0.3	0.4	1.1	0.3	-0.3	0.3	0.8	0.1	0.4	-0.6	-0.6	0.9	1.0	0.8
Time to tail flick, test, before self-admin	0.8	0.9	2.6	0.9	-0.9	0.9	0.3	-0.2	0.8	0.9	-1.6	-0.8	1.6	0.3
Time to tail flick, test, after self-admin	0.5	0.5	1.6	0.7	-0.8	0.6	-1.1	-0.3	0.7	1.3	0.0	-0.8	-0.2	0.0
Delta time to tail flick, vehicle, before/after SA	1.4	1.3	3.3	1.1	-1.2	1.3	-1.2	-1.8	1.5	1.1	-0.4	0.1	0.4	1.2
Delta time to tail flick, test, before/after SA	0.4	0.4	1.7	-0.4	0.5	-0.6	-0.4	0.3	-0.5	-0.3	1.3	0.6	-1.0	-0.0
Tibia length	0.9	2.5	5.4	0.9	-0.8	1.8	-2.3	-2.2	1.6	2.2	-1.3	-1.7	0.5	0.3
Ambulatory time before self-admin	0.7	1.1	3.2	-1.1	1.1	-0.9	0.5	1.3	-1.1	0.0	0.5	-1.0	-0.9	-1.8
Ambulatory time after self-admin	0.4	0.5	2.1	-0.5	0.5	-0.4	0.4	0.7	-0.6	-1.5	-0.4	0.9	0.6	0.1
Bone: tissue strength	0.8	0.8	3.0	-0.8	0.9	-0.6	0.6	0.4	-0.5	-1.1	-0.2	1.7	1.0	0.9
Total heroin consumption	0.5	0.6	2.1	0.5	-0.4	0.6	-1.0	-0.7	0.5	0.5	1.0	-0.6	-1.5	-0.4
Bone: trabecular number	0.2	0.3	0.8	0.6	-0.6	0.5	-0.5	-0.5	0.5	0.9	-0.5	-0.9	0.3	-0.3
Bone: trabecular spacing	0.1	0.1	0.2	-0.3	0.4	-0.4	0.0	0.1	-0.5	-0.1	-0.0	-0.2	-0.2	-0.4
Bone: trabecular thickness	0.5	0.6	0.9	0.9	-0.9	1.0	-0.6	-0.6	0.9	0.5	-1.0	-0.1	0.9	0.8
Bone: trabecular tissue density	7.9	11.6	21.0	3.6	-3.5	4.2	-4.6	-4.6	4.1	3.4	-2.1	-2.0	1.1	2.4
Water consumed over 24 hours	1.4	1.9	4.6	-1.5	1.3	-1.4	1.1	1.1	-1.3	-0.4	1.8	0.0	-2.2	-1.7
Number of responses in last shaping day	1.8	1.9	4.7	-0.8	0.9	-1.0	1.5	1.3	-1.0	-0.3	1.9	-1.1	-2.2	-2.1