Hub : Genes

Ube2u

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg isoform ratio XM_063261314.1 0.1 0.07 9.9e-03 0.1 0.08 0.04 0.09 1.4e-03 4.5e-03 3.4e-02 2.7e-03
2 RMTg intron excision ratio chr5_120237842_120244009 0.13 0.1 7.1e-03 0.02 -0 -0.01 -0 1.1e-01 4.0e-01 6.8e-01 3.9e-01
3 Brain gene expression Ube2u 0.06 0.04 2.1e-05 0.06 0.06 0.06 0.05 2.9e-06 7.6e-06 5.4e-06 1.0e-05
4 pVTA intron excision ratio chr5_120234397_120237750 0.04 0.03 5.7e-03 0.03 0.02 0.02 0.02 1.8e-03 1.5e-02 1.5e-02 5.2e-03
5 Brain intron excision ratio chr5_120234397_120237750 0.07 0.05 1.9e-04 0.03 0.03 0.03 0.03 4.2e-04 2.0e-03 1.4e-03 7.6e-04
6 BLA gene expression Ube2u 0.09 0.08 1.0e-02 0.05 0.01 0.04 0.03 1.7e-03 7.7e-02 4.4e-03 9.1e-03
7 IL isoform ratio XM_006238443.5 0.16 0.1 5.8e-03 0.06 0.03 0 0.02 1.6e-02 5.5e-02 2.7e-01 8.7e-02
8 BLA isoform ratio XM_063261314.1 0.12 0.08 1.8e-03 0.05 0.02 0.04 0.03 9.6e-04 3.4e-02 5.8e-03 9.0e-03
9 NAcc gene expression Ube2u 0.11 0.04 0.0e+00 0.1 0.13 0.13 0.13 9.9e-15 1.4e-18 1.7e-18 4.0e-19
10 RMTg alternative TSS XM_063261314.1 0.2 0.14 9.9e-03 0.04 0.04 -0.01 0.03 3.4e-02 2.7e-02 6.0e-01 5.0e-02
11 PL gene expression Ube2u 0.1 0.04 3.8e-10 0.06 0.08 0.07 0.07 9.8e-07 2.1e-09 1.4e-08 6.2e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.30.61.4-0.80.9-0.71.21.1-0.7-0.80.4-0.80.20.1
Area under the delay curve1.52.46.0-2.42.3-2.20.90.5-1.9-0.31.3-1.50.90.6
BMI with tail0.72.44.21.7-1.32.0-1.7-1.72.11.3-1.20.1-1.1-1.8
BMI without tail0.63.16.02.0-1.92.4-1.9-2.02.41.6-1.11.0-0.8-1.3
Body weight0.52.23.81.7-1.61.7-1.8-1.81.80.5-1.0-0.3-1.1-2.0
Weight adjusted by age0.20.41.8-0.50.6-0.3-0.7-0.2-0.20.61.10.21.40.4
Bone surface1.22.44.02.0-1.91.9-1.4-1.41.81.3-1.50.8-1.3-1.3
Bone volume0.10.10.30.5-0.40.5-0.4-0.40.50.2-0.2-0.1-0.2-0.5
Breakpoint value in progressive ratio session0.30.62.40.5-0.50.40.1-0.30.6-0.5-1.1-0.7-1.5-1.2
Number of licking bursts0.00.10.5-0.40.30.0-0.6-0.60.00.7-0.3-0.0-0.4-0.1
Context. condit. distance diff. score1.01.25.7-0.40.3-0.61.01.0-0.4-1.50.1-2.4-0.7-1.2
Locomotion velocity, session 11.31.44.41.2-1.50.9-0.9-1.00.80.9-2.10.8-1.5-0.8
Locomotion distance, session 10.20.20.7-0.2-0.0-0.80.60.4-0.8-0.5-0.3-0.1-0.30.2
Locomotion velocity, session 20.20.20.7-0.20.2-0.30.60.7-0.40.0-0.30.6-0.10.9
Locomotion distance, session 20.70.92.21.2-1.20.6-0.3-0.30.61.1-1.41.5-0.90.2
Locomotion velocity, session 30.10.10.5-0.20.1-0.30.10.1-0.40.00.50.10.70.4
Locomotion distance, session 30.00.00.1-0.30.1-0.1-0.3-0.3-0.2-0.10.2-0.30.1-0.1
Stereotopy head waving bouts, day 31.51.82.6-1.11.1-1.61.41.3-1.6-1.41.6-0.41.51.1
Stereotopy head waving duration, day 31.41.82.6-1.21.2-1.51.51.4-1.5-1.01.5-0.31.61.3
Locomotion velocity, session 70.60.61.7-0.70.5-0.91.31.2-0.9-0.80.1-0.5-0.10.5
Locomotion distance, session 70.40.51.2-0.40.1-0.71.11.0-0.8-0.8-0.6-0.5-1.00.0
Stereotopy head waving bouts, day 70.40.41.20.5-0.50.6-1.1-1.00.60.9-0.20.60.5-0.1
Stereotopy head waving duration, day 70.80.92.20.7-0.60.9-1.3-1.30.91.5-0.51.10.60.1
Locomotion velocity, session 80.10.20.60.2-0.30.10.0-0.10.20.1-0.8-0.4-0.7-0.4
Locomotion distance, session 80.20.30.80.4-0.5-0.30.80.8-0.2-0.4-0.7-0.3-0.9-0.2
Degree of sensitization distance0.30.41.80.5-0.40.20.30.10.2-0.2-1.0-0.1-1.4-0.6
Degree of sensitization stereotypy0.91.02.30.8-0.61.1-1.5-1.41.11.4-0.20.90.6-0.0
Conditioned locomotion0.10.10.40.0-0.1-0.1-0.5-0.70.10.4-0.1-0.1-0.1-0.1
Cocaine response after cond. corrected0.30.51.30.2-0.30.7-1.1-1.10.41.1-0.40.7-0.10.0
Cocaine response after cond. not corrected0.50.71.30.6-0.70.9-1.1-1.10.60.9-0.90.8-0.7-0.2
Cocaine response before conditioning0.30.41.10.9-0.80.30.10.40.4-0.3-1.00.6-1.0-0.2
Saline control response0.00.10.20.2-0.00.3-0.3-0.30.30.3-0.00.40.00.3
Bone: connectivity density1.11.72.61.5-1.31.6-1.1-1.11.61.5-1.41.0-1.0-0.9
Bone: cortical apparent density2.74.39.1-2.22.1-2.53.03.0-2.3-1.71.2-1.10.71.6
Bone: cortical area0.61.02.11.2-1.21.2-0.6-0.61.01.30.51.40.70.3
Bone: cortical porosity0.80.92.91.0-0.81.7-0.8-1.01.60.8-0.10.40.2-0.6
Bone: cortical porosity1.11.33.31.0-0.91.8-1.2-1.41.81.0-0.40.4-0.2-0.9
Bone: cortical thickness0.20.42.20.1-0.10.10.00.20.20.11.50.01.30.2
Bone: cortical thickness0.10.10.20.4-0.4-0.00.10.10.1-0.40.4-0.3-0.0-0.5
Bone: cortical tissue density2.64.28.9-2.22.0-2.53.02.9-2.3-1.71.1-1.10.61.5
Condit. Reinf. active minus inactive responses1.01.12.31.5-1.31.1-0.7-0.71.01.3-0.71.5-0.7-0.2
Condit. Reinf. active-inactive response ratio1.01.02.01.4-1.21.4-0.7-0.81.21.2-0.41.1-0.5-0.4
Condit. Reinf. active responses1.41.93.61.9-1.61.4-1.3-1.31.31.7-0.91.9-0.5-0.2
Condit. Reinf. inactive responses0.60.71.10.9-0.90.6-1.0-1.00.61.0-1.11.1-0.5-0.2
Incentive salience index mean1.72.25.22.3-2.01.5-0.9-0.91.41.7-1.02.1-0.8-0.2
Condit. Reinf. lever presses1.42.15.72.4-2.21.4-0.8-0.71.21.2-1.41.7-1.2-0.5
Condit. Reinf. active minus inactive responses0.20.41.20.3-0.4-0.41.01.0-0.6-1.1-0.3-0.0-0.5-0.0
Condit. Reinf. active-inactive response ratio0.20.31.00.6-0.70.30.50.40.1-0.2-1.00.7-0.90.1
Condit. Reinf. active responses0.30.51.20.7-0.9-0.00.60.8-0.2-1.1-0.8-0.1-1.0-0.6
Condit. Reinf. inactive responses0.50.72.2-0.50.4-0.91.01.2-0.8-1.50.6-0.90.2-0.1
Condit. Reinf. lever presses3.04.49.82.7-2.81.8-1.6-1.41.51.5-3.12.2-2.3-0.9
Condit. Reinf. lever reinforcers received0.30.51.20.8-1.00.10.20.5-0.0-0.8-1.00.1-1.1-0.6
Conditioned reinforcement - actives0.00.20.70.5-0.40.5-0.2-0.10.40.6-0.40.8-0.30.1
Conditioned reinforcement - inactives0.10.41.60.2-0.40.1-0.1-0.30.1-0.7-0.4-1.2-0.7-1.1
Conditioned locomotion0.30.40.80.8-0.40.9-0.6-0.80.90.7-0.50.6-0.5-0.3
Patch foraging indifference point 0 sec3.39.319.02.8-3.22.9-4.4-4.23.02.5-3.01.1-2.5-2.6
Patch foraging indifference point AUC0.61.52.81.1-1.11.1-1.2-1.11.01.6-1.61.7-0.80.0
Delay disc. indifference point, 0s delay3.23.79.4-2.72.6-2.31.51.1-1.9-1.81.0-3.10.1-0.4
Delay disc. indifference point, 16s delay0.40.63.0-0.1-0.20.0-1.2-1.40.11.70.00.50.30.0
Delay disc. indifference point, 2s delay2.02.26.4-2.11.9-1.90.70.5-1.9-1.10.9-2.50.3-0.4
Delay disc. indifference point, 24s delay0.20.30.6-0.70.7-0.80.1-0.3-0.70.60.30.30.40.7
Delay disc. indifference point, 4s delay5.15.410.8-3.33.1-3.12.22.0-2.5-1.42.1-2.31.41.1
Delay disc. indifference point, 8s delay1.52.55.4-2.32.2-2.21.51.0-2.0-0.81.1-1.00.71.0
Indifference point function ln k0.20.71.8-0.30.5-0.61.20.9-0.5-1.41.0-1.10.1-0.3
Indifference point function log k0.20.71.8-0.30.5-0.61.20.9-0.5-1.41.0-1.10.1-0.3
Patch foraging total patch changes 0 sec3.19.218.22.8-3.22.8-4.3-4.13.02.5-3.21.1-2.7-2.6
Patch foraging total patch changes 12 sec1.21.74.10.8-1.20.7-2.0-2.00.91.4-1.60.9-1.1-0.7
Patch foraging total patch changes 18 sec2.55.88.02.4-2.72.4-2.8-2.72.62.2-2.81.1-2.3-2.0
Patch foraging total patch changes 24 sec0.92.95.61.6-1.81.7-2.3-2.41.91.3-1.50.2-1.3-1.7
Patch foraging total patch changes 6 sec3.25.411.32.1-2.42.4-3.4-3.22.52.5-2.01.7-1.1-1.3
Patch foraging time to switch 0 sec0.62.34.8-1.61.6-1.41.41.2-1.3-0.42.1-0.02.21.8
Patch foraging water rate 0 sec0.31.12.31.0-1.31.1-1.5-1.41.10.8-0.70.6-0.8-0.8
Patch foraging water rate 12 sec1.45.88.82.8-2.92.9-2.3-2.23.01.6-2.20.8-2.5-2.4
Patch foraging water rate 18 sec0.51.22.30.8-1.11.4-1.0-1.01.50.8-0.9-0.2-1.1-1.4
Patch foraging water rate 24 sec0.30.41.80.3-0.70.7-0.2-0.20.8-0.1-0.1-1.0-0.7-1.4
Patch foraging water rate 6 sec0.10.20.50.2-0.40.00.40.4-0.0-0.7-0.1-0.5-0.5-0.6
Seeking ratio, delayed vs. immediate footshock1.31.85.60.7-0.81.0-0.3-0.51.0-0.5-1.3-2.0-2.2-2.4
Distance traveled before self-admin0.51.02.31.2-1.21.1-0.8-1.51.20.7-0.5-0.1-0.7-1.3
Distance traveled after self-admin0.20.31.30.3-0.40.1-0.5-0.60.31.10.20.80.40.2
Extensor digitorum longus weight0.31.04.9-0.50.4-0.50.00.3-0.2-0.91.7-2.20.8-1.2
Bone: elastic displacement0.30.40.9-0.30.2-0.60.60.7-0.4-0.9-0.3-1.0-0.5-0.6
Bone: elastic work1.11.42.7-1.01.0-1.21.01.1-1.1-1.51.6-1.41.20.1
Bone: endosteal estimation0.82.03.61.8-1.91.7-1.0-1.11.50.6-1.60.7-1.7-1.2
Bone: endosteal perimeter0.82.13.71.7-1.71.7-1.0-1.21.61.9-1.21.8-0.7-0.1
Epididymis fat weight0.00.10.30.5-0.50.5-0.2-0.10.40.00.10.2-0.1-0.1
Delta time in closed arm before/after self-admin1.00.94.00.1-0.20.5-0.7-1.00.5-0.0-1.6-0.5-2.0-1.1
Delta time in open arm before/after self-admin1.01.14.71.0-1.00.6-0.8-0.20.51.60.32.21.01.1
Diff in mean of infusions in LGA sessions0.81.53.31.0-1.11.3-1.1-1.01.50.3-1.70.2-1.8-1.2
Delay discount exponential model param1.72.35.82.4-2.22.2-0.9-0.51.80.2-1.41.4-1.0-0.7
Extinction: sum of active levers before priming0.40.63.1-0.50.5-0.20.30.3-0.1-1.1-0.1-1.8-0.8-1.0
Active lever presses in extinction session 61.51.53.11.1-1.31.3-0.8-1.11.60.4-1.4-0.4-1.6-1.8
Bone: final force0.20.31.00.3-0.40.40.40.40.20.01.00.41.00.6
Bone: final moment0.30.51.11.0-1.01.0-0.3-0.20.80.50.60.70.60.1
Food consumed during 24 hour testing period0.20.51.6-0.00.3-0.50.80.8-0.5-0.4-0.21.2-0.11.2
Glucose0.40.71.60.9-0.81.2-0.3-0.51.20.7-0.90.2-0.8-0.9
Heart weight0.60.93.1-0.10.5-0.11.11.0-0.2-1.80.9-1.70.1-0.7
Delay discount hyperbolic model param2.22.86.92.6-2.52.4-1.0-0.72.00.3-1.51.6-1.2-0.8
Intermittent access intake day 1-15 change0.21.33.7-0.91.1-0.70.40.5-0.80.71.50.91.91.7
Intermittent access intake escalation0.52.56.3-1.61.7-1.50.71.0-1.30.32.20.52.52.1
Intermittent access intake escalation 20.40.62.0-0.50.6-0.50.30.3-0.60.61.00.71.41.2
Intermitt. access day 1 inactive lever presses0.11.35.30.8-0.60.8-0.4-0.71.1-0.4-0.6-1.8-1.1-2.3
Intermitt. access day 15 inactive lever presses0.10.71.90.20.10.01.11.10.0-1.4-0.4-1.1-1.1-0.6
Intermitt. access escalation Index1.33.96.2-2.32.0-2.52.02.3-2.1-1.12.0-0.22.12.1
Intermittent access day 1 total infusions0.10.20.8-0.40.1-0.10.90.70.1-0.80.0-0.6-0.3-0.1
Intermittent access day 15 total infusions0.81.93.6-1.71.6-1.41.01.1-1.1-0.31.90.01.91.7
Intermittent access terminal intake (last 3 days)0.20.30.7-0.70.7-0.40.50.5-0.3-0.00.70.10.80.7
Intermittent access total infusions0.40.51.2-1.00.9-0.60.60.6-0.4-0.41.1-0.20.90.7
Intermittent access day 1 locomotion0.10.21.20.5-0.40.5-0.1-0.10.60.5-0.11.10.00.4
Intermittent access day 15 total locomotion0.20.93.20.9-0.71.0-0.1-0.41.11.50.21.80.70.9
Intermittent access total locomotion0.40.51.60.7-0.60.8-0.2-0.30.91.00.31.30.50.5
Intermittent access standard deviation0.00.10.4-0.20.70.30.40.20.10.10.50.40.40.5
Left kidney weight0.00.40.70.8-0.70.7-0.5-0.40.7-0.30.5-0.60.4-0.8
Right kidney weight0.10.61.90.4-0.20.10.50.5-0.0-1.31.4-1.21.0-0.6
Cocaine induced anxiety1.43.88.7-1.91.6-1.90.11.5-2.00.22.71.42.93.0
Post-drug Anxiety4.75.410.7-2.62.3-2.51.02.1-2.6-1.23.3-0.13.12.5
Baseline Anxiety0.40.72.8-0.40.4-0.41.10.3-0.4-1.40.4-1.70.1-0.8
Tail length0.00.10.40.3-0.60.1-0.2-0.1-0.0-0.60.60.10.20.1
Length with tail0.10.30.70.5-0.80.2-0.8-0.70.3-0.60.1-0.5-0.2-0.7
Length without tail0.20.93.10.6-0.70.6-1.1-1.20.7-0.2-0.0-1.2-0.4-1.8
Times rat made contact with spout0.91.01.51.2-1.11.2-0.9-0.91.20.7-1.20.5-1.0-0.9
Lifetime Intake0.70.91.8-1.21.1-0.80.50.8-0.7-0.51.3-0.11.31.1
Liver weight, left1.01.84.0-1.31.4-1.01.91.8-0.9-1.70.4-2.0-0.6-0.2
Liver weight, right0.71.36.6-0.50.7-0.50.50.3-0.6-1.80.5-2.6-0.6-1.5
Locomotor activity0.10.10.50.2-0.20.2-0.7-0.4-0.0-0.10.5-0.40.3-0.4
Locomotor testing distance0.61.64.11.3-1.51.5-2.0-1.71.20.7-0.70.4-0.5-1.0
Locomotor testing rearing0.10.20.90.2-0.40.4-1.0-0.80.30.0-0.1-0.0-0.1-0.3
Locomotion in novel chamber1.52.13.71.8-1.71.9-1.0-1.91.81.7-0.50.9-0.3-0.8
Locomotion in novel chamber post-restriction0.20.51.30.1-0.1-0.70.60.2-0.40.61.01.11.01.2
Fecal boli incidents, locomotor time 10.10.41.1-0.50.5-0.20.00.0-0.50.40.80.91.10.9
Change in fecal boli incidents, locomotor task0.20.30.8-0.40.5-0.50.10.5-0.6-0.80.1-0.9-0.2-0.2
Time >=10cm from walls, locomotor time 10.80.93.9-1.00.7-0.7-0.1-0.2-0.60.21.9-0.42.00.6
Bouts of movement, locomotor time 11.41.95.50.7-0.81.3-1.2-1.51.80.5-0.9-1.5-1.5-2.4
Total resting periods, locomotor time 11.41.65.20.5-0.71.1-1.1-1.31.50.2-0.9-1.5-1.4-2.3
Rest time, locomotor task time 10.30.41.20.4-0.50.5-0.2-0.20.5-0.3-0.8-0.7-1.0-1.1
Distance moved, locomotor task time 10.10.30.6-0.50.2-0.40.70.5-0.8-0.6-0.50.2-0.30.6
Vertical activity count, locomotor time 10.10.71.8-1.00.6-0.60.80.5-0.9-0.51.00.11.30.9
Time >=10cm from walls, locomotor time 20.71.94.0-1.21.5-0.71.31.1-0.8-1.72.0-1.91.60.1
Bouts of movement, locomotor time 20.30.92.21.0-0.81.3-0.8-1.11.41.50.20.10.3-0.9
Total resting periods, locomotor time 20.20.71.90.8-0.71.0-0.9-1.11.11.40.20.20.3-0.7
Rest time, locomotor task time 20.10.10.4-0.50.3-0.6-0.1-0.2-0.4-0.2-0.0-0.3-0.2-0.2
Distance moved, locomotor task time 20.50.72.0-0.1-0.00.21.01.2-0.3-1.4-0.9-0.8-1.1-0.2
Vertical activity count, locomotor time 20.10.20.8-0.1-0.10.40.60.5-0.2-0.90.3-0.60.3-0.1
Light reinforcement 10.21.03.61.0-1.40.50.30.00.3-0.4-1.6-0.3-1.9-1.3
Light reinforcement 20.10.20.80.2-0.3-0.30.90.6-0.4-0.60.2-0.5-0.3-0.4
Bone: marrow area0.82.03.61.8-1.91.6-0.9-1.11.50.6-1.60.7-1.8-1.2
Bone: maximum diameter0.51.02.61.0-1.01.2-0.8-0.91.01.50.31.60.70.5
Bone: maximum force0.30.51.41.1-1.21.1-0.3-0.20.90.60.20.90.10.0
Bone: maximum moment0.81.63.71.9-1.91.7-1.0-1.01.51.1-0.31.1-0.3-0.6
Mean time between licks in bursts0.95.19.3-2.32.3-2.72.92.5-2.5-3.11.3-2.60.10.3
Mean num. licks in bursts0.20.51.71.2-1.30.8-0.1-0.20.8-0.2-0.50.5-0.2-0.5
Cd content in liver3.43.85.82.3-2.42.0-1.6-1.72.01.8-2.41.8-2.0-0.9
Co content in liver2.32.77.01.8-2.01.3-0.9-0.81.40.2-1.9-0.9-2.6-2.5
Cu content in liver0.20.30.5-0.50.3-0.60.60.5-0.5-0.70.7-0.70.40.1
Fe content in liver2.22.79.90.9-1.01.2-0.6-1.11.5-0.3-1.3-2.3-2.4-3.1
K content in liver1.11.12.4-0.80.7-1.01.51.5-0.9-1.21.1-1.10.60.2
Mg content in liver0.50.51.90.2-0.20.10.20.20.20.70.81.21.41.1
Mn content in liver0.30.40.80.7-0.80.6-0.4-0.60.70.90.10.80.20.1
Na content in liver1.31.55.6-0.50.4-1.12.42.1-0.9-1.50.5-1.00.10.1
Rb content in liver0.20.20.4-0.60.5-0.70.50.4-0.6-0.40.5-0.50.20.0
Se content in liver1.01.23.60.8-1.00.7-0.6-0.90.8-0.0-1.2-1.2-1.6-1.9
Sr content in liver2.32.04.81.6-1.51.5-0.3-0.61.51.4-2.21.2-2.0-0.7
Zn content in liver1.11.23.81.2-1.30.9-0.8-0.71.01.7-0.31.90.40.6
Bone: minimum diameter0.81.42.71.2-1.31.7-1.3-1.41.51.50.31.10.5-0.3
Time in familiar zone, hab. session 10.91.02.9-1.11.0-0.60.90.8-0.6-1.01.4-1.70.6-0.3
Time in novel zone, hab. session 12.73.04.81.8-1.81.5-1.8-1.81.62.1-2.22.1-1.1-0.2
Total zone transitions, hab. session 11.21.63.2-1.11.1-1.70.91.0-1.6-1.01.8-0.51.61.1
Total locomotion distance, hab. session 10.30.41.2-0.20.2-0.80.50.6-1.0-1.10.8-0.40.60.3
Locomotion velocity, hab. session 10.50.61.5-0.40.4-1.00.50.7-1.2-1.01.1-0.30.90.6
Time in familiar zone, hab. session 20.10.10.2-0.00.00.5-0.2-0.10.50.40.5-0.30.3-0.2
Time in novel zone, hab. session 20.10.10.30.2-0.3-0.1-0.3-0.40.20.3-0.60.5-0.30.1
Total zone transitions, hab. session 23.95.08.5-2.32.2-2.92.72.7-2.7-2.11.6-1.01.31.8
Total locomotion distance, hab. session 23.34.36.8-2.01.8-2.62.42.4-2.6-2.22.1-1.11.71.5
Locomotion velocity, hab. session 23.24.36.7-2.01.8-2.62.42.4-2.6-2.12.1-0.91.71.7
Novel to familiar place preference ratio0.81.02.01.4-1.21.2-1.0-1.11.20.9-0.81.0-0.1-0.3
Novelty place preference0.60.71.51.2-1.01.1-0.8-0.91.20.7-0.80.6-0.3-0.4
Time in novel zone, NPP test0.91.12.01.4-1.21.3-0.9-1.01.40.8-1.00.6-0.5-0.7
Total zone transitions, NPP test1.31.93.0-1.41.3-1.71.51.4-1.7-1.01.5-0.61.41.2
Total locomotion distance, NPP test1.11.62.7-1.11.0-1.51.31.3-1.6-1.41.4-0.51.21.1
Locomotion velocity, NPP test1.11.62.9-1.21.0-1.61.31.3-1.7-1.31.4-0.41.31.2
Intraocular pressure0.50.91.5-0.90.8-1.21.11.1-1.2-0.31.1-0.10.81.0
Delta distance traveled before/after self-admin0.60.61.4-0.60.5-0.4-0.40.3-0.51.00.71.01.21.2
Delta ambulatory time before/after self-admin0.61.12.7-1.11.0-0.80.00.8-0.90.80.91.01.51.6
Parametrial fat weight4.510.616.34.0-4.03.8-3.4-3.63.73.3-2.82.4-1.8-1.9
Pavlov. Cond. lever latency2.43.06.4-2.52.5-1.62.01.8-1.5-1.41.4-1.21.21.4
Pavlov. Cond. magazine entry latency0.20.20.80.7-0.50.2-0.6-0.50.00.40.20.90.40.4
Pavlov. Cond. change in total contacts1.92.14.22.1-2.01.5-1.4-1.31.41.4-1.11.6-0.8-0.6
Pavlov. Cond. index score1.31.73.81.9-1.81.1-1.7-1.51.01.0-1.01.1-0.8-0.9
Pavlov. Cond. latency score1.41.83.81.9-1.81.2-1.7-1.51.11.1-1.01.1-0.8-0.9
Pavlov. Cond. lever contacts1.82.14.42.1-2.11.3-1.7-1.51.31.2-1.11.1-1.0-1.1
Pavlov. Cond. magazine entry number0.20.20.6-0.60.4-0.10.60.30.0-0.4-0.3-0.8-0.3-0.3
Pavlov. Cond. intertrial magazine entries1.72.03.7-1.41.4-1.61.51.4-1.7-0.91.30.51.31.9
Pavlov. Cond. lever-magazine prob. diff.1.41.73.81.9-1.81.0-1.7-1.50.91.1-0.91.2-0.7-0.8
Pavlov. Cond. response bias0.91.13.01.7-1.50.9-1.3-1.10.70.9-0.51.1-0.4-0.5
Pavlov. Cond. lever latency1.92.77.7-2.02.0-1.01.61.3-0.7-1.71.9-2.80.9-0.4
Pavlov. Cond. magazine entry latency1.52.23.51.6-1.51.4-1.6-1.51.31.9-1.71.9-1.0-0.1
Pavlov. Cond. change in total contacts0.71.74.71.7-1.70.9-1.2-1.00.61.4-1.52.2-0.80.2
Pavlov. Cond. index score1.42.34.11.9-1.81.3-1.5-1.31.11.5-1.82.0-1.2-0.2
Pavlov. Cond. latency score1.32.13.71.8-1.81.2-1.4-1.31.01.4-1.91.8-1.4-0.3
Pavlov. Cond. lever contacts1.92.78.12.0-2.01.0-1.5-1.20.81.8-2.02.8-1.00.4
Pavlov. Cond. magazine entry number0.60.82.0-0.90.8-0.61.00.9-0.6-1.30.7-1.40.2-0.3
Pavlov. Cond. intertrial magazine entries1.32.85.1-2.02.0-1.61.51.5-1.6-1.52.3-1.21.81.1
Pavlov. Cond. lever-magazine prob. diff.1.42.24.01.8-1.81.3-1.4-1.31.11.5-1.82.0-1.2-0.2
Pavlov. Cond. response bias1.62.37.11.8-1.81.0-1.5-1.20.81.8-1.62.7-0.60.5
Time in closed arm before self-admin0.91.65.0-0.80.8-0.91.01.1-0.90.31.81.02.21.9
Time in closed arm after self-admin0.20.20.7-0.80.8-0.40.0-0.1-0.3-0.3-0.1-0.6-0.30.1
Time in open arm before self-admin1.41.74.40.6-0.50.9-1.2-1.21.0-0.1-1.7-1.3-2.0-2.1
Time in open arm after self-admin1.51.63.41.7-1.61.4-1.8-1.01.31.4-0.41.50.2-0.4
Bone: periosteal estimation0.71.73.61.9-1.91.7-1.0-1.11.61.1-0.61.2-0.6-0.6
Bone: periosteal perimeter0.91.83.81.5-1.61.6-0.8-0.91.51.9-0.72.0-0.20.2
Bone: post-yield work2.23.87.62.6-2.82.3-1.4-1.42.02.1-1.62.0-1.4-0.6
Progressive ratio test 1 active lever presses0.81.52.7-1.51.5-1.41.41.6-1.4-0.80.6-0.10.51.1
Progressive ratio test 1 breakpoint1.01.73.2-1.61.6-1.51.51.8-1.6-1.00.6-0.20.51.2
Progressive ratio test 1 inactive lever presses0.51.32.9-1.41.2-1.11.51.7-1.1-1.11.0-0.80.50.7
Progressive ratio test 2 active lever presses0.20.20.8-0.30.3-0.40.30.3-0.20.60.10.90.30.9
Progressive ratio test 2 breakpoint0.30.31.0-0.50.5-0.50.50.4-0.40.50.30.90.51.0
Progressive ratio test 2 inactive lever presses0.00.10.2-0.30.2-0.40.30.3-0.10.10.20.20.10.3
Incentive Sensitization - Responses0.10.31.20.4-0.30.20.0-0.10.31.00.41.10.60.8
Incentive Sensitization - Breakpoint0.20.41.50.4-0.30.3-0.1-0.30.41.10.41.20.70.8
Sum of active levers in priming session hrs 5-62.82.78.60.4-0.30.20.5-0.10.3-1.5-1.8-2.6-2.9-2.7
Progressive ratio0.10.31.3-0.60.5-0.50.30.3-0.80.10.20.60.31.1
Food seeking constrained by brief footshock2.12.66.4-1.31.4-1.72.02.1-2.0-2.5-0.3-1.4-1.00.4
Seeking ratio, punishment vs. effort0.30.61.70.10.1-0.30.91.0-0.2-1.3-0.3-1.2-0.8-0.8
Retroperitoneal fat weight0.31.22.91.1-1.51.2-1.4-1.71.20.9-0.30.4-0.1-0.8
Reaction time number correct0.20.61.9-0.30.3-0.81.01.2-0.8-0.4-0.01.00.21.4
Reaction time mean minus median0.21.63.21.2-1.01.3-1.2-1.11.21.8-1.61.6-1.0-0.1
Reaction time mean minus median AUC0.10.61.40.7-0.40.7-0.4-0.40.61.1-1.11.2-0.60.2
Reaction time num false alarms0.10.10.60.2-0.1-0.1-0.4-0.1-0.4-0.0-0.50.8-0.30.3
Reaction time num false alarms AUC0.20.61.80.9-0.80.4-0.9-0.60.10.5-1.01.3-0.60.1
Reaction time trials correct on left0.20.61.9-0.30.3-0.81.01.2-0.8-0.4-0.01.00.21.4
Reaction time trials on left0.20.51.8-0.20.2-0.70.91.1-0.7-0.3-0.11.10.11.3
Reaction time mean0.30.71.90.6-0.20.8-1.0-1.11.01.4-0.80.6-0.4-0.4
Reaction time mean AUC0.20.41.10.40.00.7-0.7-0.90.81.0-0.70.2-0.5-0.5
Median of all reaction times0.20.31.20.20.10.5-0.7-0.90.71.1-0.40.3-0.2-0.3
Reaction time omissions1.32.13.41.5-1.31.4-1.4-1.41.51.8-1.81.5-1.3-0.5
Reaction time false alarm rate0.60.81.91.0-0.90.9-1.4-1.10.60.7-0.90.9-0.5-0.5
Reaction time premature initiation rate0.10.20.8-0.20.10.00.30.2-0.1-0.5-0.1-0.9-0.5-0.7
Reaction time premature initiations0.10.30.8-0.40.3-0.50.90.9-0.6-0.80.0-0.5-0.30.1
Std. dev. reaction times0.93.15.01.8-1.41.8-1.9-1.92.02.2-2.11.4-1.5-1.0
Reaction time trials completed0.20.51.8-0.20.2-0.70.91.1-0.7-0.3-0.11.10.11.3
Reaction time trials AUC0.20.61.9-0.20.2-0.70.81.0-0.7-0.3-0.01.10.31.4
Run reversals in cocaine runway, females0.40.42.30.10.00.2-0.3-0.30.5-0.4-0.3-1.5-0.5-1.2
Run reversals in cocaine runway, males1.11.22.51.5-1.60.8-1.5-1.10.71.3-0.70.5-0.8-0.7
Latency to leave start box in cocaine runway0.40.51.90.5-0.4-0.10.80.8-0.0-0.8-1.0-0.2-1.4-0.5
Latency to leave start box in cocaine runway, F0.40.51.40.8-0.70.5-0.10.00.60.2-1.20.7-1.1-0.2
Latency to leave start box in cocaine runway, M0.70.72.0-0.10.2-0.60.90.8-0.6-1.3-0.2-1.4-0.9-0.8
Std. dev. time between licks in bursts0.50.93.5-0.30.3-0.60.1-0.2-0.3-0.8-0.7-1.9-1.4-1.5
Total sessions with >9 infusions1.01.32.4-1.51.5-1.10.20.8-1.2-0.81.4-0.41.41.2
Short access day 1 total inactive lever presses0.10.31.10.2-0.40.4-0.50.10.4-0.2-0.0-0.9-0.3-1.1
Short access day 10 total inactive lever presses0.43.07.51.9-1.81.9-1.5-1.62.0-0.0-1.4-1.3-1.8-2.7
Short access day 1 total infusions0.40.81.6-1.31.2-0.90.41.0-1.0-1.00.8-0.70.60.5
Short access day 10 total infusions0.00.00.1-0.30.30.2-0.0-0.00.2-0.20.3-0.10.10.1
Short access total infusions0.30.40.9-0.90.9-0.50.00.6-0.5-0.30.80.00.80.8
Short access day 1 locomotion0.10.20.60.30.30.4-0.60.20.20.20.10.80.30.5
Short access day 10 total locomotion0.41.84.51.7-1.12.1-1.4-1.61.91.2-0.51.0-0.4-0.7
Short access total locomotion0.20.20.8-0.00.50.3-0.5-0.00.10.20.40.90.50.8
One hour access (0.3 mA shock)1.01.24.20.9-0.60.8-0.2-0.40.81.80.62.11.11.0
Compulsive drug intake0.71.12.51.2-1.00.9-1.5-1.01.01.60.41.10.8-0.2
One hour access (shock baseline)0.30.81.5-1.01.0-0.61.10.8-0.5-0.11.20.11.21.1
Social response proportion0.30.41.70.0-0.20.1-0.0-0.10.31.10.11.30.41.0
Social responses0.50.73.10.4-0.70.2-0.3-0.20.30.5-1.60.4-1.8-0.4
Social time0.40.61.30.6-0.80.5-0.7-0.50.41.1-1.11.0-1.1-0.0
Soleus weight0.10.41.30.9-0.90.40.20.10.40.6-0.51.1-0.20.5
Bone: stiffness0.20.41.40.9-0.91.2-0.2-0.20.90.70.30.60.20.0
Tibialis anterior weight5.217.930.54.7-4.74.6-5.5-5.24.94.9-2.73.1-1.2-2.5
Time to tail flick, vehicle, before self-admin1.11.43.41.1-1.11.3-1.4-1.81.51.6-0.20.60.2-0.7
Time to tail flick, vehicle, after self-admin0.20.41.1-0.30.3-0.3-0.8-0.1-0.40.60.60.91.00.8
Time to tail flick, test, before self-admin0.80.92.6-0.90.9-0.9-0.30.2-0.8-0.91.6-0.81.60.3
Time to tail flick, test, after self-admin0.50.51.6-0.70.8-0.61.10.3-0.7-1.3-0.0-0.8-0.20.0
Delta time to tail flick, vehicle, before/after SA1.21.33.3-1.11.2-1.31.21.8-1.5-1.10.40.10.41.2
Delta time to tail flick, test, before/after SA0.30.41.70.4-0.50.60.4-0.30.50.3-1.30.6-1.0-0.0
Tibia length0.92.55.4-0.90.8-1.82.32.2-1.6-2.21.3-1.70.50.3
Ambulatory time before self-admin0.31.13.21.1-1.10.9-0.5-1.31.1-0.0-0.5-1.0-0.9-1.8
Ambulatory time after self-admin0.30.52.10.5-0.50.4-0.4-0.70.61.50.40.90.60.1
Bone: tissue strength0.80.83.00.8-0.90.6-0.6-0.40.51.10.21.71.00.9
Total heroin consumption0.50.62.1-0.50.4-0.61.00.7-0.5-0.5-1.0-0.6-1.5-0.4
Bone: trabecular number0.20.30.8-0.60.6-0.50.50.5-0.5-0.90.5-0.90.3-0.3
Bone: trabecular spacing0.10.10.20.3-0.40.4-0.0-0.10.50.10.0-0.2-0.2-0.4
Bone: trabecular thickness0.40.60.9-0.90.9-1.00.60.6-0.9-0.51.0-0.10.90.8
Bone: trabecular tissue density6.611.621.0-3.63.5-4.24.64.6-4.1-3.42.1-2.01.12.4
Water consumed over 24 hours1.01.94.61.5-1.31.4-1.1-1.11.30.4-1.80.0-2.2-1.7
Number of responses in last shaping day1.51.94.70.8-0.91.0-1.5-1.31.00.3-1.9-1.1-2.2-2.1