Hub : Traits

Time in familiar zone, hab. session 1

Time in familiar zone during first habituation session for males and females [sec]

Tags: Behavior · Motivation · Novelty

Project: p50_shelly_flagel_2014

1 significantly associated model · 1 unique gene

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Body weight 2.1 1 0 0 0 1 Shld1
Length with tail 1.5 1 0 0 0 1 Shld1
Liver weight, left 2.8 1 0 0 0 1 Shld1
Extensor digitorum longus weight 1.4 1 0 0 0 1 Shld1
Soleus weight 6.0 1 0 0 0 1 Shld1
Tibialis anterior weight 2.4 1 0 0 0 1 Shld1
Food consumed during 24 hour testing period 3.5 1 0 0 0 1 Shld1
Mean time between licks in bursts 6.3 1 0 0 0 1 Shld1
Std. dev. time between licks in bursts 5.8 1 0 0 0 1 Shld1
Indifference point 0 sec 5.4 1 0 0 0 1 Shld1
Indifference point AUC 5.8 1 0 0 0 1 Shld1
Delay discounting total patch changes 0 sec 4.1 1 0 0 0 1 Shld1
Delay discounting total patch changes 12 sec 8.3 1 0 0 0 1 Shld1
Delay discounting total patch changes 6 sec 14.7 1 0 0 0 1 Shld1
Locomotor activity 2.9 1 0 0 0 1 Shld1
Light reinforcement 2 3.1 1 0 0 0 1 Shld1
Reaction time num false alarms AUC 2.9 1 0 0 0 1 Shld1
Reaction time false alarm rate 4.9 1 0 0 0 1 Shld1
Reaction time premature initiations 2.8 1 0 0 0 1 Shld1
Condit. Reinf. inactive responses 3.5 1 0 0 0 1 Shld1
Pavlov. Cond. intertrial magazine entries 8.7 1 0 0 0 1 Shld1
Intermitt. access day 1 inactive lever presses 4.3 1 0 0 0 1 Shld1
Intermitt. access day 15 inactive lever presses 3.5 1 0 0 0 1 Shld1
Short access day 10 total inactive lever presses 7.8 1 0 0 0 1 Shld1
Locomotion velocity, session 3 4.0 1 0 0 0 1 Shld1
Locomotion velocity, session 7 12.5 1 0 0 0 1 Shld1
Condit. Reinf. inactive responses 7.5 1 0 0 0 1 Shld1
Time in novel zone, hab. session 1 11.6 1 0 0 0 1 Shld1
Total zone transitions, hab. session 1 5.2 1 0 0 0 1 Shld1
Time in familiar zone, hab. session 2 36.1 1 1 Inf 0 1 Shld1
Time in novel zone, hab. session 2 32.2 1 1 Inf 0 1 Shld1
Pavlov. Cond. intertrial magazine entries 5.5 1 0 0 0 1 Shld1
Bone surface 3.1 1 0 0 0 1 Shld1
Bone volume 4.1 1 0 0 0 1 Shld1
Bone: cortical apparent density 4.9 1 0 0 0 1 Shld1
Bone: cortical area 4.4 1 0 0 0 1 Shld1
Bone: cortical thickness 2.7 1 0 0 0 1 Shld1
Bone: cortical tissue density 5.8 1 0 0 0 1 Shld1
Bone: maximum diameter 7.0 1 0 0 0 1 Shld1
Bone: minimum diameter 3.0 1 0 0 0 1 Shld1
Bone: periosteal perimeter 2.6 1 0 0 0 1 Shld1
Bone: trabecular thickness 4.7 1 0 0 0 1 Shld1
Bone: trabecular tissue density 5.6 1 0 0 0 1 Shld1
Time in open arm after self-admin 3.6 1 0 0 0 1 Shld1
Delta time to tail flick, test, before/after SA 10.7 1 0 0 0 1 Shld1
Delay disc. indifference point, 4s delay 6.4 1 0 0 0 1 Shld1
Delay disc. indifference point, 8s delay 13.0 1 0 0 0 1 Shld1
Distance moved, locomotor task time 1 4.4 1 0 0 0 1 Shld1
Progressive ratio 11.7 1 0 0 0 1 Shld1
Seeking ratio, punishment vs. effort 5.0 1 0 0 0 1 Shld1
Run reversals in cocaine runway, males 4.7 1 0 0 0 1 Shld1
Fe content in liver 3.6 1 0 0 0 1 Shld1

chisq ratio: Average Chi2 statistic for the selected genes in the secondary trait, divided by the average statistic for all genes in the secondary trait. # genes+: Shared significant genes at Bonferroni correction. # genes++: Shared significant genes at transcriptome-wide significance. % genes++: Number of [++] genes as a percentage of primary trait’s total joint genes. corr: Correlation of effect sizes across the [+] genes.

Associations by panel

tissue modality # hits % hits/tests avg chisq
Adipose alternative polyA 0 0.000 1.01
Adipose alternative TSS 0 0.000 1.01
Adipose gene expression 0 0.000 0.94
Adipose isoform ratio 0 0.000 0.95
Adipose intron excision ratio 0 0.000 1.13
Adipose mRNA stability 0 0.000 0.92
BLA alternative polyA 0 0.000 0.89
BLA alternative TSS 0 0.000 0.98
BLA gene expression 0 0.000 0.91
BLA isoform ratio 0 0.000 0.98
BLA intron excision ratio 0 0.000 1.03
BLA mRNA stability 0 0.000 0.90
Brain alternative polyA 0 0.000 0.96
Brain alternative TSS 0 0.000 0.92
Brain gene expression 0 0.000 0.92
Brain isoform ratio 0 0.000 0.99
Brain intron excision ratio 0 0.000 0.99
Brain mRNA stability 0 0.000 0.90
Eye alternative polyA 0 0.000 1.12
Eye alternative TSS 0 0.000 1.00
Eye gene expression 0 0.000 0.91
Eye isoform ratio 0 0.000 0.89
Eye intron excision ratio 0 0.000 0.94
Eye mRNA stability 0 0.000 0.82
IL alternative polyA 0 0.000 0.94
IL alternative TSS 0 0.000 0.91
IL gene expression 0 0.000 0.90
IL isoform ratio 0 0.000 0.92
IL intron excision ratio 0 0.000 0.93
IL mRNA stability 0 0.000 0.85
LHb alternative polyA 0 0.000 1.01
LHb alternative TSS 0 0.000 0.93
LHb gene expression 0 0.000 0.92
LHb isoform ratio 0 0.000 0.95
LHb intron excision ratio 0 0.000 1.04
LHb mRNA stability 0 0.000 0.96
Liver alternative polyA 0 0.000 0.96
Liver alternative TSS 0 0.000 0.93
Liver gene expression 0 0.000 0.93
Liver isoform ratio 0 0.000 1.02
Liver intron excision ratio 1 0.023 0.99
Liver mRNA stability 0 0.000 0.90
NAcc alternative polyA 0 0.000 0.88
NAcc alternative TSS 0 0.000 0.98
NAcc gene expression 0 0.000 0.92
NAcc isoform ratio 0 0.000 0.97
NAcc intron excision ratio 0 0.000 0.96
NAcc mRNA stability 0 0.000 0.87
OFC alternative polyA 0 0.000 0.83
OFC alternative TSS 0 0.000 1.31
OFC gene expression 0 0.000 0.89
OFC isoform ratio 0 0.000 1.01
OFC intron excision ratio 0 0.000 1.11
OFC mRNA stability 0 0.000 0.86
PL alternative polyA 0 0.000 0.91
PL alternative TSS 0 0.000 0.95
PL gene expression 0 0.000 0.91
PL isoform ratio 0 0.000 0.99
PL intron excision ratio 0 0.000 1.03
PL mRNA stability 0 0.000 0.91

avg chisq: Average Chi2 (squared Z-score) across all models in this panel for this trait.