Hub : Traits

Liver weight, left

Tags: Physiology · Liver · Weight

Project: dissection

1 locus · 1 gene with independent associations · 1 total associated gene

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr1	76658582	78051660	1	1	1.74e-08	2.87e-06	1.13e-75	LOC120099769

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	1.97	1	0	0	0	1e+00	LOC120099769
BMI without tail	2.07	1	0	0	0	1e+00	LOC120099769
Body weight	1.43	1	0	0	0	1e+00	LOC120099769
Left kidney weight	4.71	1	0	0	0	1e+00	LOC120099769
Right kidney weight	3.2	1	0	0	0	1e+00	LOC120099769
Liver weight, right	9.65	1	0	0	0	1e+00	LOC120099769
Food consumed during 24 hour testing period	3.75	1	0	0	0	1e+00	LOC120099769
Patch foraging indifference point AUC	4.01	1	0	0	0	1e+00	LOC120099769
Indifference point function ln k	3.01	1	0	0	0	1e+00	LOC120099769
Indifference point function log k	3.01	1	0	0	0	1e+00	LOC120099769
Patch foraging time to switch 0 sec	3.75	1	0	0	0	1e+00	LOC120099769
Patch foraging water rate 0 sec	2.62	1	0	0	0	1e+00	LOC120099769
Locomotor testing rearing	4.72	1	0	0	0	1e+00	LOC120099769
Reaction time num false alarms	5.24	1	0	0	0	1e+00	LOC120099769
Reaction time num false alarms AUC	5.09	1	0	0	0	1e+00	LOC120099769
Locomotion velocity, session 7	3.87	1	0	0	0	1e+00	LOC120099769
Bone: elastic displacement	3.41	1	0	0	0	1e+00	LOC120099769
Breakpoint value in progressive ratio session	7.06	1	0	0	0	1e+00	LOC120099769
Sum of active levers in priming session hrs 5-6	4.74	1	0	0	0	1e+00	LOC120099769
Ambulatory time after self-admin	7.78	1	0	0	0	1e+00	LOC120099769
Total resting periods, locomotor time 1	4.06	1	0	0	0	1e+00	LOC120099769
Bouts of movement, locomotor time 2	7.61	1	0	0	0	1e+00	LOC120099769
Total resting periods, locomotor time 2	8.47	1	0	0	0	1e+00	LOC120099769
Food seeking constrained by brief footshock	3.27	1	0	0	0	1e+00	LOC120099769
Se content in liver	5.3	1	0	0	0	1e+00	LOC120099769

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.67
Adipose	alternative TSS	0	0	1.54
Adipose	gene expression	0	0	1.61
Adipose	isoform ratio	0	0	1.56
Adipose	intron excision ratio	0	0	1.51
Adipose	mRNA stability	0	0	1.56
BLA	alternative polyA	0	0	1.55
BLA	alternative TSS	0	0	1.67
BLA	gene expression	0	0	1.62
BLA	isoform ratio	0	0	1.68
BLA	intron excision ratio	0	0	1.57
BLA	mRNA stability	0	0	1.66
Brain	alternative polyA	0	0	1.57
Brain	alternative TSS	0	0	1.64
Brain	gene expression	1	0	1.58
Brain	isoform ratio	0	0	1.62
Brain	intron excision ratio	0	0	1.57
Brain	mRNA stability	0	0	1.57
Eye	alternative polyA	0	0	1.7
Eye	alternative TSS	0	0	1.78
Eye	gene expression	0	0	1.69
Eye	isoform ratio	0	0	1.76
Eye	intron excision ratio	0	0	1.55
Eye	mRNA stability	0	0	1.57
IL	alternative polyA	0	0	1.55
IL	alternative TSS	0	0	1.83
IL	gene expression	0	0	1.6
IL	isoform ratio	0	0	1.77
IL	intron excision ratio	0	0	1.59
IL	mRNA stability	0	0	1.65
LHb	alternative polyA	0	0	1.61
LHb	alternative TSS	0	0	1.61
LHb	gene expression	0	0	1.67
LHb	isoform ratio	0	0	1.64
LHb	intron excision ratio	0	0	1.54
LHb	mRNA stability	0	0	1.67
Liver	alternative polyA	0	0	1.63
Liver	alternative TSS	0	0	1.61
Liver	gene expression	0	0	1.6
Liver	isoform ratio	0	0	1.56
Liver	intron excision ratio	0	0	1.49
Liver	mRNA stability	0	0	1.64
NAcc	alternative polyA	0	0	1.55
NAcc	alternative TSS	0	0	1.64
NAcc	gene expression	0	0	1.62
NAcc	isoform ratio	0	0	1.61
NAcc	intron excision ratio	0	0	1.6
NAcc	mRNA stability	0	0	1.59
OFC	alternative polyA	0	0	1.64
OFC	alternative TSS	0	0	1.83
OFC	gene expression	0	0	1.68
OFC	isoform ratio	0	0	1.73
OFC	intron excision ratio	0	0	1.49
OFC	mRNA stability	0	0	1.7
PL	alternative polyA	0	0	1.59
PL	alternative TSS	0	0	1.68
PL	gene expression	0	0	1.61
PL	isoform ratio	0	0	1.63
PL	intron excision ratio	0	0	1.55
PL	mRNA stability	0	0	1.61
pVTA	alternative polyA	0	0	1.53
pVTA	alternative TSS	0	0	1.64
pVTA	gene expression	0	0	1.6
pVTA	isoform ratio	0	0	1.6
pVTA	intron excision ratio	0	0	1.53
pVTA	mRNA stability	0	0	1.54
RMTg	alternative polyA	0	0	1.55
RMTg	alternative TSS	0	0	1.67
RMTg	gene expression	0	0	1.62
RMTg	isoform ratio	0	0	1.44
RMTg	intron excision ratio	0	0	1.54
RMTg	mRNA stability	0	0	1.42