Hub : Genes

Tuba1a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr7_130092476_130093543 0.11 0.09 1.9e-10 0.11 0.11 0.13 0.12 2.3e-10 1.6e-10 6.4e-12 6.4e-11
2 BLA mRNA stability Tuba1a 0.32 0.18 5.6e-17 0.31 0.3 0.31 0.32 6.2e-17 1.3e-16 7.4e-17 1.7e-17
3 Brain intron excision ratio chr7_130115057_130116812 0.13 0.09 1.4e-14 0.16 0.16 0.18 0.16 4.6e-15 2.1e-14 1.3e-16 5.3e-15
4 BLA gene expression Tuba1a 0.17 0.15 4.1e-07 0.11 0.11 0.09 0.1 2.7e-06 1.2e-06 2.6e-05 3.4e-06
5 Brain gene expression Tuba1a 0.81 0.11 0.0e+00 0.46 0.47 0.48 0.47 6.0e-48 1.0e-48 1.4e-49 6.1e-49
6 OFC gene expression Tuba1a 0.57 0.2 3.7e-11 0.24 0.26 0.28 0.3 1.6e-06 5.2e-07 1.8e-07 8.8e-08
7 Eye gene expression Tuba1a 0.87 0.11 1.4e-03 0.19 0.14 0.16 0.17 7.6e-04 3.1e-03 1.9e-03 1.6e-03
8 Adipose gene expression Tuba1a 0.5 0.17 0.0e+00 0.46 0.48 0.48 0.48 4.1e-57 1.1e-60 1.4e-60 2.0e-60
9 NAcc mRNA stability Tuba1a 0.08 0.07 2.4e-08 0.06 0.06 0.05 0.06 9.2e-08 6.5e-08 1.2e-06 1.5e-07
10 pVTA mRNA stability Tuba1a 0.45 0.3 1.8e-15 0.3 0.31 0.31 0.34 1.3e-13 4.9e-14 3.5e-14 3.1e-15
11 IL gene expression Tuba1a 0.32 0.17 1.1e-06 0.18 0.23 0.21 0.23 4.0e-05 2.4e-06 8.3e-06 2.7e-06
12 BLA intron excision ratio chr7_130092476_130093543 0.16 0.14 3.4e-07 0.12 0.12 0.12 0.12 5.8e-07 3.8e-07 6.3e-07 6.4e-07
13 Brain mRNA stability Tuba1a 0.05 0.04 9.6e-05 0.04 0.04 0.02 0.03 3.0e-04 1.1e-04 3.1e-03 4.0e-04
14 pVTA gene expression Tuba1a 0.41 0.13 0.0e+00 0.44 0.45 0.44 0.44 5.9e-21 3.1e-21 4.1e-21 3.9e-21
15 PL intron excision ratio chr7_130115057_130116812 0.04 0.04 4.6e-05 0.04 0.04 0.04 0.04 1.9e-05 5.5e-05 1.7e-05 2.8e-05
16 PL intron excision ratio chr7_130092476_130093543 0.06 0.05 6.7e-06 0.05 0.04 0.04 0.05 3.9e-06 9.3e-06 8.7e-06 7.2e-06
17 LHb gene expression Tuba1a 0.45 0.19 3.7e-09 0.3 0.29 0.27 0.3 6.9e-08 1.3e-07 3.7e-07 5.8e-08
18 BLA intron excision ratio chr7_130115057_130116812 0.09 0.08 2.0e-04 0.08 0.07 0.06 0.08 4.1e-05 9.7e-05 4.0e-04 6.7e-05
19 PL gene expression Tuba1a 0.1 0.09 2.5e-08 0.07 0.07 0.07 0.07 4.1e-08 3.1e-08 2.1e-08 3.5e-08
20 NAcc gene expression Tuba1a 0.26 0.07 5.1e-03 0 0 0.01 -0 2.7e-01 6.9e-02 7.2e-03 6.9e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density10.417.420.8-4.6-4.34.24.2-4.2-4.3-4.3-4.2-4.2-4.2-4.24.2-4.24.24.3-4.2-4.24.0-3.43.3
Area under the delay curve0.80.91.2-0.7-1.10.81.0-0.8-1.0-1.0-1.0-1.0-1.1-1.01.0-1.01.00.9-0.9-0.81.0-1.10.3
BMI with tail4.213.717.7-3.8-3.83.83.8-3.5-3.6-3.6-3.8-3.8-3.9-3.73.8-3.83.93.6-3.8-3.64.2-3.72.0
BMI without tail0.10.21.8-0.00.1-0.1-0.10.40.30.30.10.1-0.10.2-0.10.10.0-0.2-0.00.20.6-0.7-1.3
Body weight5.924.631.3-4.6-5.14.95.1-4.8-4.9-4.9-5.1-5.2-5.3-5.05.1-5.25.25.0-5.0-5.05.6-4.72.7
Weight adjusted by age2.02.23.3-1.4-1.51.51.5-1.4-1.4-1.4-1.5-1.5-1.6-1.51.5-1.61.61.5-1.6-1.51.8-1.60.6
Bone surface12.221.525.4-5.0-4.84.74.7-4.7-4.8-4.8-4.7-4.7-4.7-4.74.7-4.74.74.8-4.7-4.74.5-3.83.5
Bone volume9.215.719.1-4.4-4.14.14.0-4.0-4.1-4.1-4.0-4.0-4.0-4.04.0-4.04.04.1-4.1-4.03.7-3.23.1
Breakpoint value in progressive ratio session0.20.20.3-0.3-0.40.40.5-0.6-0.4-0.4-0.5-0.5-0.4-0.50.5-0.50.50.4-0.4-0.20.5-0.40.4
Number of licking bursts0.50.62.71.10.6-0.7-0.70.80.80.80.70.60.50.8-0.70.6-0.6-0.80.50.8-0.1-0.0-1.7
Context. condit. distance diff. score0.20.20.5-0.3-0.50.40.5-0.4-0.5-0.5-0.5-0.5-0.5-0.50.5-0.50.50.4-0.4-0.40.7-0.50.3
Locomotion velocity, session 11.11.21.91.31.1-1.2-1.01.11.11.11.11.11.11.0-1.11.1-1.1-1.11.11.0-1.41.1-0.4
Locomotion distance, session 13.03.86.22.12.0-2.2-1.91.91.91.91.91.92.01.8-1.92.0-2.0-1.92.21.8-2.52.1-0.7
Locomotion velocity, session 20.30.31.20.60.5-0.6-0.50.50.40.40.50.50.40.5-0.50.5-0.5-0.40.60.4-1.10.9-0.1
Locomotion distance, session 22.43.35.81.91.8-2.0-1.81.81.71.71.81.81.81.7-1.81.8-1.8-1.72.01.7-2.42.0-0.8
Locomotion velocity, session 33.84.56.12.02.1-2.1-2.22.32.12.12.22.22.22.2-2.22.2-2.2-2.12.22.1-2.51.9-1.5
Locomotion distance, session 35.05.47.32.32.3-2.4-2.42.42.22.22.42.42.42.4-2.42.4-2.4-2.22.42.2-2.72.4-1.4
Stereotopy head waving bouts, day 31.31.52.1-1.4-1.41.41.2-1.2-1.3-1.3-1.2-1.2-1.3-1.11.2-1.21.21.3-1.3-1.30.9-1.00.9
Stereotopy head waving duration, day 30.70.81.6-1.3-0.91.10.9-0.8-0.9-0.9-0.8-0.8-0.9-0.90.9-0.80.80.9-1.0-0.90.4-0.70.9
Locomotion velocity, session 70.20.30.50.70.4-0.6-0.50.50.40.40.50.50.50.5-0.50.5-0.5-0.50.60.4-0.50.6-0.5
Locomotion distance, session 71.72.22.61.61.4-1.6-1.51.51.41.41.51.51.51.5-1.51.4-1.5-1.51.61.4-1.21.4-1.3
Stereotopy head waving bouts, day 71.11.32.3-1.5-1.21.41.0-1.0-1.1-1.1-1.0-1.1-1.2-1.01.1-1.11.11.2-1.5-1.11.0-1.40.4
Stereotopy head waving duration, day 71.41.72.8-1.7-1.31.61.2-1.2-1.2-1.2-1.2-1.2-1.3-1.21.3-1.21.31.3-1.6-1.21.2-1.60.6
Locomotion velocity, session 80.00.00.10.30.0-0.10.10.10.00.0-0.1-0.1-0.1-0.10.0-0.00.1-0.10.10.0-0.20.00.1
Locomotion distance, session 81.21.82.61.51.4-1.6-1.31.41.31.31.31.31.31.2-1.31.3-1.3-1.41.61.3-1.51.4-0.5
Degree of sensitization distance0.50.51.4-0.6-0.70.70.7-0.6-0.7-0.7-0.7-0.7-0.7-0.70.7-0.70.70.6-0.7-0.71.2-0.70.2
Degree of sensitization stereotypy0.20.30.9-0.6-0.50.60.4-0.4-0.3-0.3-0.4-0.4-0.5-0.30.4-0.40.50.5-0.8-0.40.5-1.0-0.3
Conditioned locomotion0.00.00.10.1-0.20.10.2-0.3-0.2-0.2-0.2-0.2-0.1-0.20.2-0.20.20.3-0.2-0.3-0.00.00.2
Cocaine response after cond. corrected0.00.00.10.10.1-0.3-0.00.10.00.00.10.10.00.0-0.10.1-0.1-0.10.20.2-0.20.30.1
Cocaine response after cond. not corrected0.60.60.90.80.8-0.9-0.80.80.70.70.80.80.70.8-0.80.8-0.8-0.81.00.9-0.90.9-0.3
Cocaine response before conditioning3.23.94.41.82.1-1.8-2.12.02.02.02.12.12.12.0-2.12.1-2.1-2.02.02.1-2.01.7-1.2
Saline control response0.10.20.4-0.5-0.40.40.4-0.4-0.5-0.5-0.4-0.4-0.4-0.40.4-0.40.40.4-0.3-0.30.4-0.10.7
Bone: connectivity density7.712.115.7-4.0-3.63.63.5-3.5-3.6-3.6-3.5-3.5-3.5-3.53.5-3.53.53.5-3.5-3.53.3-2.82.8
Bone: cortical apparent density0.30.40.60.70.6-0.7-0.60.50.50.50.60.60.60.6-0.60.6-0.7-0.70.80.6-0.40.8-0.2
Bone: cortical area9.814.717.2-4.1-4.04.03.8-3.8-3.8-3.8-3.9-3.9-4.0-3.83.9-3.94.03.9-4.1-3.84.0-3.82.1
Bone: cortical porosity0.70.81.80.50.9-0.6-0.90.70.80.80.90.91.10.8-0.91.0-1.0-0.70.90.7-1.21.30.5
Bone: cortical porosity1.11.22.30.71.1-0.8-1.11.01.01.01.11.21.31.0-1.11.2-1.2-0.91.10.9-1.41.50.3
Bone: cortical thickness3.55.87.7-2.5-2.52.52.4-2.2-2.3-2.3-2.4-2.5-2.6-2.32.4-2.52.62.4-2.7-2.32.5-2.80.6
Bone: cortical thickness0.10.10.5-0.1-0.30.20.3-0.2-0.3-0.3-0.4-0.4-0.5-0.30.4-0.40.40.3-0.4-0.30.7-0.6-0.5
Bone: cortical tissue density0.40.50.80.90.7-0.8-0.70.60.60.60.70.70.80.7-0.70.7-0.8-0.80.90.7-0.50.9-0.2
Condit. Reinf. active minus inactive responses0.10.10.40.10.3-0.3-0.20.20.20.20.20.20.20.2-0.20.2-0.3-0.20.20.2-0.60.50.0
Condit. Reinf. active-inactive response ratio0.20.20.8-0.5-0.50.40.5-0.6-0.6-0.6-0.5-0.5-0.4-0.50.5-0.50.40.5-0.4-0.50.10.10.9
Condit. Reinf. active responses0.60.71.40.90.9-1.0-0.80.80.80.80.80.80.80.8-0.80.8-0.8-0.80.80.8-1.20.9-0.7
Condit. Reinf. inactive responses2.83.34.22.11.9-1.9-1.81.91.91.91.81.81.81.8-1.81.8-1.8-1.91.81.9-1.81.5-1.6
Incentive salience index mean0.00.00.00.0-0.1-0.00.1-0.1-0.1-0.1-0.2-0.2-0.2-0.10.2-0.20.20.1-0.1-0.1-0.00.0-0.2
Condit. Reinf. lever presses0.10.10.20.2-0.30.00.4-0.3-0.3-0.3-0.4-0.4-0.5-0.30.4-0.50.50.4-0.3-0.40.3-0.3-0.4
Condit. Reinf. active minus inactive responses0.00.00.1-0.20.10.1-0.10.10.10.10.10.10.20.1-0.10.2-0.2-0.00.00.10.00.20.1
Condit. Reinf. active-inactive response ratio0.30.30.40.40.6-0.5-0.60.60.60.60.60.60.60.6-0.60.6-0.6-0.60.50.6-0.50.4-0.6
Condit. Reinf. active responses0.10.20.30.00.4-0.1-0.50.50.40.40.50.50.50.5-0.50.5-0.5-0.40.40.4-0.20.4-0.1
Condit. Reinf. inactive responses0.50.60.80.50.8-0.6-0.90.90.80.80.90.90.90.9-0.90.9-0.9-0.80.80.8-0.60.7-0.3
Condit. Reinf. lever presses0.00.00.1-0.2-0.10.2-0.0-0.1-0.1-0.10.00.00.0-0.0-0.00.0-0.00.0-0.0-0.00.30.00.2
Condit. Reinf. lever reinforcers received0.40.60.80.40.8-0.5-0.90.80.80.80.90.90.90.8-0.90.9-0.9-0.70.70.8-0.50.7-0.3
Conditioned reinforcement - actives1.61.62.11.21.3-1.2-1.31.41.51.51.31.31.31.3-1.31.3-1.2-1.21.21.1-1.00.6-1.5
Conditioned reinforcement - inactives2.12.33.51.51.6-1.6-1.61.71.71.71.51.51.51.6-1.51.5-1.5-1.31.41.3-1.30.8-1.9
Conditioned locomotion0.40.40.80.60.8-0.5-0.70.90.90.90.70.70.70.7-0.70.7-0.6-0.50.50.4-0.30.1-0.9
Patch foraging indifference point 0 sec2.13.43.91.81.9-1.8-1.91.92.02.01.91.91.81.9-1.91.9-1.9-1.91.71.9-1.71.2-1.6
Patch foraging indifference point AUC0.20.21.2-0.00.4-0.3-0.50.50.50.50.50.50.30.6-0.50.5-0.4-0.30.20.3-0.2-0.1-1.1
Delay disc. indifference point, 0s delay1.31.42.4-1.5-1.21.41.2-1.0-1.1-1.1-1.2-1.2-1.2-1.11.2-1.21.21.2-1.3-1.21.0-1.20.7
Delay disc. indifference point, 16s delay0.90.91.4-0.8-1.00.91.0-0.8-0.8-0.8-1.0-1.0-1.0-0.91.0-1.01.00.9-1.0-0.91.2-1.20.1
Delay disc. indifference point, 2s delay1.31.51.9-1.1-1.31.11.3-1.3-1.4-1.4-1.3-1.3-1.3-1.31.3-1.31.21.1-1.1-1.21.1-0.81.2
Delay disc. indifference point, 24s delay1.31.31.6-0.9-1.21.11.2-1.1-1.1-1.1-1.2-1.2-1.2-1.11.2-1.21.21.2-1.2-1.11.3-1.30.4
Delay disc. indifference point, 4s delay0.20.20.4-0.2-0.60.30.5-0.4-0.6-0.6-0.5-0.5-0.6-0.50.5-0.50.50.4-0.3-0.40.4-0.30.4
Delay disc. indifference point, 8s delay2.42.53.2-1.2-1.71.41.6-1.5-1.5-1.5-1.6-1.7-1.7-1.61.7-1.71.71.6-1.6-1.51.7-1.80.6
Indifference point function ln k3.75.15.7-2.1-2.42.32.4-2.4-2.4-2.4-2.3-2.3-2.2-2.42.3-2.32.32.3-2.2-2.32.0-1.72.1
Indifference point function log k3.75.15.7-2.1-2.42.32.4-2.4-2.4-2.4-2.3-2.3-2.2-2.42.3-2.32.32.3-2.2-2.32.0-1.72.1
Patch foraging total patch changes 0 sec2.03.23.71.71.8-1.7-1.91.91.91.91.91.91.81.9-1.91.9-1.8-1.91.71.9-1.71.2-1.6
Patch foraging total patch changes 12 sec2.12.75.31.61.7-1.6-1.71.71.81.81.71.61.51.8-1.61.6-1.6-1.61.41.6-1.20.7-2.3
Patch foraging total patch changes 18 sec3.84.95.71.82.3-2.0-2.42.32.32.32.42.42.22.4-2.32.3-2.3-2.22.12.3-2.01.6-2.2
Patch foraging total patch changes 24 sec2.02.43.71.51.5-1.5-1.61.61.61.61.61.61.51.7-1.61.6-1.6-1.51.41.6-1.30.9-1.9
Patch foraging total patch changes 6 sec2.33.44.31.61.9-1.8-2.02.02.02.02.01.91.82.0-1.91.9-1.9-1.81.71.8-1.61.2-2.1
Patch foraging time to switch 0 sec2.53.86.02.52.0-2.1-1.91.81.81.81.91.91.91.9-1.91.9-1.9-2.12.22.0-1.82.1-1.2
Patch foraging water rate 0 sec3.04.86.6-2.6-2.32.42.2-2.1-2.1-2.1-2.2-2.2-2.3-2.12.2-2.22.32.3-2.4-2.12.0-2.31.2
Patch foraging water rate 12 sec3.85.76.5-2.5-2.52.52.4-2.3-2.5-2.5-2.4-2.4-2.4-2.42.4-2.42.42.5-2.4-2.52.1-1.92.3
Patch foraging water rate 18 sec0.20.30.5-0.5-0.60.60.6-0.5-0.5-0.5-0.6-0.6-0.5-0.60.6-0.60.60.5-0.6-0.50.7-0.70.5
Patch foraging water rate 24 sec3.24.45.4-2.3-2.22.32.1-2.0-2.2-2.2-2.1-2.1-2.1-2.12.1-2.12.12.1-2.2-2.01.9-1.71.9
Patch foraging water rate 6 sec3.75.46.1-2.4-2.52.52.4-2.3-2.4-2.4-2.4-2.4-2.3-2.32.4-2.42.42.4-2.5-2.42.1-2.01.9
Seeking ratio, delayed vs. immediate footshock0.30.30.5-0.5-0.60.50.6-0.5-0.5-0.5-0.6-0.6-0.6-0.50.6-0.60.60.6-0.7-0.60.5-0.70.0
Distance traveled before self-admin1.21.32.11.51.1-1.3-1.11.11.11.11.11.11.11.1-1.11.1-1.1-1.11.31.1-1.21.0-0.8
Distance traveled after self-admin0.20.20.50.50.4-0.5-0.40.40.40.40.40.40.40.4-0.40.4-0.4-0.40.50.3-0.70.5-0.2
Extensor digitorum longus weight3.614.320.9-2.9-3.93.64.0-3.7-3.6-3.6-4.0-4.0-4.1-3.84.0-4.04.13.8-3.8-3.74.6-4.01.4
Bone: elastic displacement4.45.06.52.32.3-2.2-2.22.12.22.22.22.32.42.1-2.32.3-2.3-2.42.42.4-2.62.4-0.7
Bone: elastic work0.10.11.50.20.0-0.00.1-0.2-0.2-0.2-0.0-0.00.1-0.20.00.0-0.1-0.00.3-0.0-0.40.81.2
Bone: endosteal estimation7.716.818.7-4.1-4.14.24.2-4.3-4.2-4.2-4.2-4.2-4.1-4.24.2-4.14.14.2-4.0-4.34.2-3.03.6
Bone: endosteal perimeter6.814.217.2-3.9-3.94.03.8-3.8-3.7-3.7-3.8-3.8-3.8-3.73.8-3.83.83.8-4.0-3.84.2-3.52.4
Epididymis fat weight0.20.40.7-0.8-0.60.70.6-0.6-0.7-0.7-0.6-0.6-0.7-0.60.6-0.60.60.6-0.4-0.70.7-0.10.8
Delta time in closed arm before/after self-admin0.30.30.5-0.7-0.50.60.5-0.7-0.5-0.5-0.5-0.5-0.5-0.50.5-0.50.50.5-0.6-0.50.4-0.40.4
Delta time in open arm before/after self-admin4.44.24.72.22.1-2.1-2.12.22.12.12.12.12.12.1-2.12.1-2.1-2.02.12.0-2.11.8-1.5
Diff in mean of infusions in LGA sessions1.51.71.9-1.2-1.41.31.4-1.4-1.3-1.3-1.3-1.3-1.3-1.41.3-1.31.31.2-1.4-1.31.1-1.21.2
Delay discount exponential model param0.70.81.10.61.0-0.7-0.90.80.90.90.91.01.00.9-0.91.0-1.0-0.80.80.8-1.01.0-0.3
Extinction: sum of active levers before priming0.40.40.9-0.8-0.60.70.7-0.8-0.7-0.7-0.7-0.7-0.6-0.70.7-0.60.70.6-0.7-0.50.4-0.40.9
Active lever presses in extinction session 60.40.40.5-0.4-0.60.50.7-0.7-0.6-0.6-0.7-0.7-0.6-0.70.7-0.70.70.7-0.6-0.60.5-0.50.4
Bone: final force9.916.117.3-4.0-4.23.94.1-4.1-4.1-4.1-4.1-4.1-4.1-4.14.1-4.14.14.1-4.0-4.13.9-3.43.1
Bone: final moment10.617.118.4-4.2-4.34.14.3-4.3-4.3-4.3-4.3-4.3-4.2-4.34.3-4.24.24.2-4.1-4.33.9-3.33.5
Food consumed during 24 hour testing period1.92.34.3-2.1-1.61.71.5-1.4-1.5-1.5-1.5-1.5-1.4-1.51.5-1.51.51.6-1.7-1.61.4-1.41.1
Glucose0.10.10.6-0.3-0.30.30.2-0.2-0.1-0.1-0.2-0.3-0.3-0.20.3-0.30.30.1-0.4-0.00.8-0.7-0.7
Heart weight0.00.10.1-0.1-0.20.20.3-0.3-0.2-0.2-0.3-0.3-0.1-0.30.3-0.20.20.3-0.3-0.30.1-0.10.4
Delay discount hyperbolic model param0.70.81.00.61.0-0.7-0.90.80.90.90.90.91.00.9-0.91.0-1.0-0.80.80.8-0.90.9-0.4
Intermittent access intake day 1-15 change1.61.62.61.51.3-1.4-1.31.31.31.31.31.21.31.3-1.21.2-1.2-1.11.21.2-0.80.9-1.6
Intermittent access intake escalation1.11.12.11.31.1-1.2-1.11.11.11.11.11.01.11.1-1.01.0-1.0-1.01.01.0-0.60.7-1.4
Intermittent access intake escalation 21.81.83.21.71.3-1.5-1.41.31.41.41.31.31.31.4-1.31.2-1.3-1.21.31.2-0.90.9-1.8
Intermitt. access day 1 inactive lever presses2.62.83.61.51.7-1.5-1.71.61.61.61.71.71.81.6-1.81.8-1.8-1.91.91.8-1.71.9-0.2
Intermitt. access day 15 inactive lever presses1.31.41.81.31.3-1.3-1.21.21.21.21.21.21.21.2-1.21.2-1.2-1.11.41.0-1.11.3-0.7
Intermitt. access escalation Index0.30.30.70.80.4-0.6-0.40.30.30.30.50.50.50.4-0.50.5-0.5-0.70.60.8-0.20.8-0.0
Intermittent access day 1 total infusions1.11.31.71.11.2-1.1-1.21.31.31.31.21.21.21.2-1.21.2-1.1-1.11.01.1-1.20.8-1.0
Intermittent access day 15 total infusions2.83.24.32.01.8-1.9-1.81.91.91.91.81.81.81.9-1.81.7-1.7-1.71.71.7-1.41.2-2.1
Intermittent access terminal intake (last 3 days)3.03.33.71.91.9-1.9-1.91.91.91.91.91.81.91.9-1.81.8-1.8-1.71.71.7-1.61.2-1.9
Intermittent access total infusions2.83.14.02.01.8-1.9-1.81.91.91.91.81.81.81.8-1.81.7-1.7-1.71.71.6-1.61.2-2.0
Intermittent access day 1 locomotion0.90.91.10.91.0-0.9-1.01.01.01.01.01.01.00.9-1.01.0-1.0-1.01.01.0-0.90.9-0.4
Intermittent access day 15 total locomotion1.71.82.71.41.5-1.3-1.41.61.61.61.41.31.41.4-1.31.3-1.3-1.21.21.2-0.90.7-1.6
Intermittent access total locomotion3.33.84.72.02.1-1.9-2.02.12.22.22.02.02.12.0-2.02.0-2.0-1.91.91.9-1.61.4-1.8
Intermittent access standard deviation0.60.61.11.00.8-0.9-0.80.80.80.80.80.80.80.8-0.80.7-0.7-0.80.80.8-0.60.5-1.0
Left kidney weight0.30.91.2-0.9-1.00.81.0-1.0-1.0-1.0-1.0-1.0-1.0-1.01.0-1.01.11.1-1.1-1.00.6-0.90.7
Right kidney weight2.67.38.2-2.6-2.72.62.8-2.7-2.6-2.6-2.8-2.8-2.8-2.72.8-2.82.82.8-2.9-2.92.8-2.71.4
Cocaine induced anxiety1.01.21.9-0.8-1.11.01.1-1.1-1.1-1.1-1.1-1.1-1.0-1.11.1-1.11.11.1-1.1-1.21.4-0.90.7
Post-drug Anxiety4.95.46.2-2.2-2.42.32.4-2.4-2.4-2.4-2.4-2.4-2.4-2.42.4-2.42.42.3-2.3-2.42.5-1.91.8
Baseline Anxiety0.90.91.2-0.8-1.00.91.0-1.0-1.0-1.0-1.0-1.0-1.1-1.01.0-1.01.01.0-1.0-0.90.8-0.80.6
Tail length0.10.31.00.50.5-0.5-0.60.70.60.60.60.50.40.6-0.50.5-0.5-0.50.50.4-0.10.1-1.0
Length with tail1.96.87.9-2.4-2.72.62.7-2.6-2.7-2.7-2.7-2.7-2.7-2.72.7-2.72.72.7-2.6-2.82.8-2.21.7
Length without tail7.215.817.5-3.5-4.13.94.2-4.1-4.1-4.1-4.2-4.2-4.1-4.14.1-4.24.24.1-4.0-4.14.0-3.22.9
Times rat made contact with spout0.10.10.70.20.3-0.2-0.30.40.40.40.30.30.20.4-0.30.3-0.2-0.40.10.5-0.2-0.2-0.9
Lifetime Intake2.83.15.62.11.8-1.9-1.81.91.91.91.71.71.71.8-1.71.7-1.6-1.61.61.6-1.51.0-2.4
Liver weight, left1.82.94.3-1.7-1.71.81.8-1.7-1.6-1.6-1.8-1.7-1.6-1.71.7-1.71.81.7-1.8-1.72.1-1.61.0
Liver weight, right1.42.43.5-1.6-1.61.61.6-1.5-1.6-1.6-1.6-1.6-1.5-1.61.6-1.61.61.5-1.6-1.51.9-1.31.0
Locomotor activity1.11.82.41.41.3-1.3-1.41.51.41.41.41.41.31.4-1.41.3-1.3-1.21.21.2-1.20.8-1.4
Locomotor testing distance2.94.85.72.32.2-2.1-2.32.42.22.22.32.32.22.3-2.32.2-2.2-2.12.12.1-2.11.7-1.9
Locomotor testing rearing2.43.75.42.31.9-1.9-2.02.01.91.91.91.91.92.0-2.01.9-1.9-2.02.01.9-1.51.5-1.7
Locomotion in novel chamber0.50.71.0-1.0-0.90.90.8-0.8-0.8-0.8-0.8-0.8-0.9-0.80.8-0.80.80.8-0.9-0.80.8-0.90.3
Locomotion in novel chamber post-restriction0.00.00.1-0.2-0.20.20.1-0.1-0.2-0.2-0.1-0.1-0.2-0.10.1-0.10.10.2-0.1-0.20.2-0.00.2
Fecal boli incidents, locomotor time 12.12.43.41.61.5-1.6-1.51.61.61.61.51.51.51.6-1.51.5-1.5-1.51.41.5-1.81.1-1.6
Change in fecal boli incidents, locomotor task1.61.52.6-1.3-1.21.21.2-1.2-1.3-1.2-1.2-1.2-1.1-1.31.2-1.21.11.3-1.1-1.40.9-0.71.6
Time >=10cm from walls, locomotor time 10.10.10.2-0.3-0.40.30.4-0.5-0.4-0.4-0.4-0.4-0.4-0.40.4-0.40.40.3-0.4-0.30.5-0.30.3
Bouts of movement, locomotor time 10.00.00.10.10.1-0.10.1-0.10.10.1-0.1-0.10.0-0.10.1-0.00.0-0.00.1-0.1-0.30.10.1
Total resting periods, locomotor time 10.20.20.60.60.6-0.5-0.40.40.60.60.40.40.50.4-0.40.5-0.5-0.50.60.4-0.80.5-0.2
Rest time, locomotor task time 10.40.40.80.70.7-0.7-0.60.60.70.70.60.60.60.6-0.60.6-0.6-0.70.60.6-0.90.3-0.5
Distance moved, locomotor task time 10.10.10.3-0.5-0.20.40.2-0.3-0.3-0.3-0.2-0.1-0.2-0.20.2-0.10.10.2-0.1-0.10.50.00.5
Vertical activity count, locomotor time 11.41.42.2-1.2-1.31.21.2-1.1-1.2-1.2-1.2-1.2-1.2-1.11.2-1.21.21.4-1.2-1.31.5-1.10.5
Time >=10cm from walls, locomotor time 20.60.71.10.70.8-0.8-0.81.00.80.80.80.80.80.9-0.80.8-0.8-0.70.70.8-1.00.5-0.8
Bouts of movement, locomotor time 22.52.73.4-1.5-1.61.51.7-1.6-1.6-1.6-1.7-1.7-1.7-1.71.7-1.71.71.7-1.6-1.91.7-1.51.0
Total resting periods, locomotor time 22.83.03.9-1.6-1.71.61.8-1.8-1.7-1.7-1.8-1.8-1.8-1.81.8-1.81.81.8-1.7-2.01.9-1.61.1
Rest time, locomotor task time 20.00.00.20.4-0.1-0.20.2-0.3-0.1-0.1-0.1-0.1-0.2-0.10.1-0.20.2-0.1-0.0-0.10.3-0.10.0
Distance moved, locomotor task time 20.10.10.2-0.10.30.0-0.30.30.20.20.30.30.40.2-0.30.3-0.3-0.20.30.3-0.40.50.3
Vertical activity count, locomotor time 20.00.10.3-0.2-0.20.30.10.1-0.1-0.1-0.1-0.1-0.1-0.00.1-0.20.20.4-0.3-0.20.2-0.3-0.5
Light reinforcement 12.74.95.62.22.3-2.1-2.42.32.32.32.32.32.32.3-2.32.3-2.3-2.22.22.2-1.81.9-1.8
Light reinforcement 21.01.31.71.31.2-1.2-1.21.21.21.21.21.21.11.1-1.11.2-1.1-1.11.11.1-1.00.9-1.1
Bone: marrow area7.616.418.2-4.0-4.14.24.1-4.2-4.2-4.2-4.1-4.1-4.1-4.24.1-4.14.14.2-4.0-4.34.1-3.03.6
Bone: maximum diameter3.97.19.3-2.9-2.82.92.6-2.5-2.5-2.5-2.6-2.7-2.8-2.52.7-2.72.82.7-3.0-2.63.1-3.00.8
Bone: maximum force14.224.526.5-4.9-5.14.95.1-5.2-5.1-5.1-5.1-5.1-5.0-5.15.1-5.15.05.0-4.8-5.14.9-3.74.4
Bone: maximum moment14.925.627.9-5.0-5.25.05.2-5.3-5.3-5.3-5.2-5.2-5.1-5.35.2-5.15.15.1-4.8-5.34.9-3.64.9
Mean time between licks in bursts0.10.21.20.40.3-0.3-0.30.30.10.10.30.30.30.2-0.30.3-0.4-0.30.60.1-0.71.10.9
Mean num. licks in bursts0.10.10.9-0.6-0.10.10.1-0.2-0.1-0.1-0.1-0.1-0.0-0.20.1-0.00.00.2-0.0-0.1-0.50.30.9
Cd content in liver0.80.92.11.40.9-1.2-0.91.00.90.90.90.90.80.9-0.90.8-0.8-0.91.00.8-0.60.8-1.3
Co content in liver0.91.06.01.60.9-1.1-0.91.01.11.10.80.80.71.0-0.80.7-0.6-0.90.60.9-0.4-0.2-2.4
Cu content in liver0.50.60.9-0.0-0.80.50.9-0.9-0.7-0.7-0.9-0.9-0.8-0.90.9-0.90.90.7-0.8-0.70.6-0.70.3
Fe content in liver0.50.52.50.70.7-0.6-0.60.80.80.80.60.60.60.7-0.60.6-0.6-0.90.50.9-0.2-0.1-1.6
K content in liver0.20.20.4-0.0-0.40.20.5-0.4-0.3-0.3-0.5-0.5-0.5-0.40.5-0.50.50.4-0.4-0.40.5-0.6-0.4
Mg content in liver0.00.00.60.20.0-0.2-0.10.10.10.10.10.1-0.00.2-0.10.0-0.0-0.00.00.0-0.2-0.3-0.8
Mn content in liver0.10.10.8-0.7-0.30.50.3-0.3-0.4-0.4-0.3-0.3-0.3-0.30.3-0.20.20.3-0.3-0.3-0.10.00.9
Na content in liver0.10.21.01.00.3-0.6-0.20.20.30.30.20.20.20.2-0.20.2-0.2-0.40.50.4-0.10.3-0.5
Rb content in liver0.40.52.20.70.7-0.6-0.70.90.80.80.70.70.60.8-0.70.6-0.6-0.70.60.8-0.20.1-1.5
Se content in liver0.60.71.50.50.8-0.6-0.91.00.90.90.90.90.80.9-0.90.8-0.8-0.80.60.9-0.70.5-1.2
Sr content in liver0.40.40.8-0.7-0.60.60.5-0.4-0.5-0.5-0.5-0.5-0.6-0.40.6-0.60.60.7-0.8-0.50.7-0.9-0.5
Zn content in liver2.02.24.11.61.4-1.5-1.51.61.61.61.51.41.41.6-1.51.4-1.4-1.51.21.6-1.30.6-2.0
Bone: minimum diameter9.117.018.8-4.2-4.34.34.1-4.1-4.1-4.1-4.2-4.2-4.1-4.14.2-4.24.24.2-4.3-4.24.3-3.73.0
Time in familiar zone, hab. session 10.30.30.60.40.5-0.5-0.50.50.50.50.50.50.60.5-0.50.5-0.5-0.60.50.5-0.80.6-0.1
Time in novel zone, hab. session 10.30.30.6-0.6-0.60.70.5-0.5-0.5-0.5-0.5-0.5-0.5-0.50.5-0.50.50.5-0.7-0.50.7-0.80.2
Total zone transitions, hab. session 10.40.50.90.90.7-0.8-0.70.90.70.70.70.70.70.7-0.70.7-0.7-0.70.80.7-0.90.7-0.4
Total locomotion distance, hab. session 10.00.10.4-0.0-0.1-0.00.1-0.1-0.2-0.2-0.1-0.1-0.1-0.10.1-0.10.00.10.2-0.2-0.30.50.6
Locomotion velocity, hab. session 10.00.10.5-0.1-0.20.10.2-0.1-0.3-0.3-0.2-0.2-0.1-0.20.2-0.20.10.20.1-0.3-0.10.40.7
Time in familiar zone, hab. session 20.30.30.7-0.8-0.50.60.6-0.6-0.6-0.6-0.6-0.6-0.5-0.60.6-0.50.50.6-0.5-0.60.3-0.40.7
Time in novel zone, hab. session 20.30.30.80.90.5-0.6-0.50.40.50.50.50.50.50.5-0.50.5-0.5-0.60.50.5-0.30.4-0.3
Total zone transitions, hab. session 20.40.51.00.80.7-0.8-0.60.90.60.60.60.60.60.6-0.60.6-0.6-0.60.80.5-1.00.8-0.4
Total locomotion distance, hab. session 20.10.21.10.40.3-0.5-0.30.40.10.10.30.30.30.3-0.30.3-0.4-0.30.60.1-0.71.00.4
Locomotion velocity, hab. session 20.10.10.70.20.1-0.4-0.10.2-0.1-0.10.20.10.10.1-0.20.1-0.2-0.10.4-0.0-0.60.80.3
Novel to familiar place preference ratio1.71.83.0-1.2-1.31.41.4-1.4-1.3-1.3-1.4-1.4-1.3-1.41.3-1.31.31.2-1.3-1.21.7-1.31.0
Novelty place preference1.31.32.4-1.0-1.11.21.2-1.2-1.1-1.1-1.2-1.1-1.1-1.21.1-1.11.11.0-1.1-1.01.5-1.10.9
Time in novel zone, NPP test1.11.12.1-1.0-1.01.21.1-1.1-1.0-1.0-1.0-1.0-1.0-1.11.0-1.01.00.9-1.0-0.91.5-1.00.9
Total zone transitions, NPP test1.42.03.11.61.4-1.6-1.41.61.41.41.41.41.31.4-1.41.4-1.3-1.41.61.3-1.81.3-1.1
Total locomotion distance, NPP test1.72.43.81.71.5-1.8-1.51.51.31.31.51.51.51.5-1.51.5-1.6-1.51.81.4-1.91.9-0.6
Locomotion velocity, NPP test0.91.32.41.31.1-1.4-1.11.21.01.01.11.11.11.1-1.11.1-1.1-1.11.41.0-1.51.5-0.5
Intraocular pressure7.410.411.33.23.3-3.4-3.33.33.33.33.33.33.23.3-3.33.3-3.3-3.33.33.2-3.12.7-2.6
Delta distance traveled before/after self-admin0.10.10.2-0.4-0.30.30.3-0.2-0.3-0.3-0.3-0.3-0.3-0.30.3-0.30.30.3-0.3-0.40.2-0.20.4
Delta ambulatory time before/after self-admin0.00.00.1-0.2-0.10.10.1-0.1-0.0-0.0-0.1-0.1-0.1-0.00.1-0.10.10.1-0.1-0.20.2-0.2-0.1
Parametrial fat weight2.14.14.61.82.1-2.1-2.12.12.12.12.12.12.02.1-2.12.0-2.0-2.12.02.2-2.01.6-1.9
Pavlov. Cond. lever latency0.20.22.9-0.2-0.20.20.4-0.6-0.4-0.4-0.3-0.3-0.1-0.50.3-0.20.20.20.0-0.30.00.31.7
Pavlov. Cond. magazine entry latency0.00.00.2-0.5-0.00.20.0-0.0-0.0-0.0-0.0-0.0-0.0-0.00.0-0.00.00.1-0.1-0.10.00.10.2
Pavlov. Cond. change in total contacts0.10.10.7-0.3-0.20.30.10.1-0.0-0.0-0.1-0.1-0.20.00.1-0.20.20.2-0.4-0.10.3-0.5-0.8
Pavlov. Cond. index score0.10.11.3-0.2-0.10.20.00.1-0.0-0.0-0.1-0.1-0.20.10.1-0.20.20.2-0.4-0.10.5-0.5-1.1
Pavlov. Cond. latency score0.10.11.7-0.2-0.10.1-0.00.20.00.0-0.0-0.0-0.20.10.0-0.10.20.1-0.3-0.10.4-0.5-1.3
Pavlov. Cond. lever contacts0.60.73.60.60.7-0.6-0.81.00.90.90.80.70.60.9-0.70.7-0.6-0.70.50.8-0.30.0-1.9
Pavlov. Cond. magazine entry number0.00.00.4-0.0-0.20.10.2-0.2-0.2-0.2-0.2-0.2-0.1-0.20.2-0.10.10.1-0.0-0.1-0.00.00.6
Pavlov. Cond. intertrial magazine entries0.40.41.40.70.6-0.8-0.60.60.60.60.60.60.60.5-0.60.6-0.6-0.60.70.7-1.20.8-0.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.7-0.4-0.40.40.4-0.2-0.3-0.3-0.4-0.4-0.5-0.30.4-0.50.50.5-0.7-0.40.7-0.8-0.9
Pavlov. Cond. response bias0.10.10.70.10.3-0.2-0.30.40.30.30.30.30.20.4-0.30.2-0.2-0.20.10.3-0.10.1-0.8
Pavlov. Cond. lever latency0.00.00.3-0.2-0.10.20.1-0.1-0.1-0.1-0.1-0.1-0.1-0.20.1-0.10.10.1-0.1-0.2-0.10.20.6
Pavlov. Cond. magazine entry latency1.21.42.1-1.4-1.21.31.2-1.2-1.1-1.1-1.2-1.2-1.1-1.21.2-1.11.11.2-1.2-1.21.1-1.01.0
Pavlov. Cond. change in total contacts1.41.93.2-1.3-1.41.41.4-1.3-1.3-1.3-1.4-1.4-1.5-1.31.4-1.41.51.3-1.5-1.31.8-1.60.1
Pavlov. Cond. index score0.50.71.0-0.9-0.80.90.8-0.8-0.8-0.8-0.8-0.8-0.8-0.80.8-0.80.80.8-0.9-0.71.0-0.90.3
Pavlov. Cond. latency score0.60.71.0-1.0-0.91.00.8-0.8-0.8-0.8-0.8-0.8-0.9-0.80.8-0.90.90.8-1.0-0.81.0-1.00.3
Pavlov. Cond. lever contacts0.10.20.50.40.4-0.4-0.40.40.40.40.40.40.40.4-0.40.4-0.4-0.40.40.5-0.10.1-0.7
Pavlov. Cond. magazine entry number2.22.73.41.71.7-1.8-1.71.61.61.61.71.71.61.6-1.71.7-1.7-1.71.71.6-1.91.6-1.0
Pavlov. Cond. intertrial magazine entries4.96.47.82.32.5-2.4-2.72.72.62.62.62.62.62.7-2.62.6-2.6-2.62.32.6-2.81.9-2.2
Pavlov. Cond. lever-magazine prob. diff.0.91.21.7-1.1-1.11.21.1-1.1-1.0-1.0-1.1-1.1-1.1-1.11.1-1.11.11.0-1.2-1.01.3-1.10.5
Pavlov. Cond. response bias0.00.00.10.10.1-0.0-0.10.10.10.10.10.10.10.1-0.10.0-0.0-0.10.00.10.2-0.1-0.3
Time in closed arm before self-admin1.41.52.6-0.9-1.21.11.3-1.3-1.2-1.2-1.3-1.3-1.2-1.31.3-1.31.31.4-1.3-1.31.6-1.00.8
Time in closed arm after self-admin0.70.71.1-0.8-0.80.80.9-1.0-0.9-0.9-0.9-0.9-0.8-0.90.9-0.90.80.9-0.9-0.91.0-0.60.7
Time in open arm before self-admin0.70.70.9-0.9-0.91.00.9-0.9-0.9-0.9-0.9-0.9-0.9-0.90.9-0.90.80.8-0.8-0.90.8-0.70.7
Time in open arm after self-admin0.30.30.60.70.6-0.5-0.50.60.60.60.50.50.60.5-0.50.6-0.5-0.60.60.5-0.80.4-0.3
Bone: periosteal estimation11.924.727.0-5.2-5.15.25.0-5.0-5.0-5.0-5.0-5.0-5.1-5.05.0-5.15.15.1-5.2-5.15.2-4.43.4
Bone: periosteal perimeter10.317.220.0-4.5-4.34.44.2-4.1-4.1-4.1-4.2-4.2-4.2-4.14.2-4.24.24.2-4.4-4.24.3-3.92.6
Bone: post-yield work8.511.612.7-3.4-3.53.53.5-3.5-3.5-3.5-3.5-3.5-3.4-3.63.5-3.43.43.5-3.2-3.63.4-2.63.4
Progressive ratio test 1 active lever presses4.95.16.32.52.3-2.3-2.32.42.42.42.32.22.32.3-2.22.2-2.2-2.22.12.3-2.01.6-2.4
Progressive ratio test 1 breakpoint4.44.65.72.42.2-2.2-2.22.32.32.32.22.12.22.2-2.12.1-2.1-2.12.02.2-1.91.4-2.3
Progressive ratio test 1 inactive lever presses3.74.14.72.22.1-2.0-2.02.22.22.22.02.02.12.0-2.02.1-2.0-2.02.02.1-1.71.5-1.7
Progressive ratio test 2 active lever presses2.72.94.72.21.7-1.9-1.71.81.81.81.71.71.71.7-1.71.6-1.6-1.61.81.5-1.31.2-1.9
Progressive ratio test 2 breakpoint3.43.85.82.42.0-2.2-2.02.02.02.01.91.91.92.0-1.91.9-1.9-1.82.01.7-1.61.4-2.1
Progressive ratio test 2 inactive lever presses2.73.14.32.11.9-1.9-1.81.91.91.91.81.81.81.8-1.81.8-1.8-1.61.91.4-1.51.4-1.6
Incentive Sensitization - Responses0.10.10.50.1-0.0-0.10.00.00.10.1-0.0-0.1-0.10.00.1-0.10.10.3-0.1-0.60.4-0.4-0.7
Incentive Sensitization - Breakpoint0.10.10.60.30.1-0.2-0.10.20.20.20.10.10.00.1-0.10.0-0.00.20.1-0.40.2-0.2-0.8
Sum of active levers in priming session hrs 5-60.10.10.10.30.2-0.2-0.10.10.20.20.10.20.30.1-0.20.2-0.2-0.20.30.2-0.30.40.3
Progressive ratio0.00.00.20.00.2-0.1-0.20.30.20.20.20.20.10.3-0.20.2-0.2-0.10.00.1-0.1-0.1-0.5
Food seeking constrained by brief footshock0.40.50.80.70.7-0.8-0.70.60.80.80.60.60.70.7-0.60.6-0.6-0.70.60.7-0.40.3-0.9
Seeking ratio, punishment vs. effort0.00.00.10.20.1-0.2-0.10.00.10.10.10.10.20.0-0.10.1-0.1-0.20.20.20.00.1-0.0
Retroperitoneal fat weight0.51.73.21.51.3-1.5-1.31.31.31.31.31.21.21.4-1.31.2-1.2-1.31.21.3-0.90.9-1.8
Reaction time number correct1.72.44.9-1.8-1.61.81.5-1.6-1.7-1.7-1.5-1.5-1.3-1.61.5-1.41.41.7-1.6-1.70.8-0.72.2
Reaction time mean minus median8.110.711.63.13.4-3.4-3.43.33.43.43.33.33.33.4-3.33.3-3.3-3.43.23.3-3.12.6-3.0
Reaction time mean minus median AUC5.87.68.42.72.9-2.9-2.82.72.82.82.82.82.92.8-2.82.8-2.8-2.92.82.8-2.62.4-2.2
Reaction time num false alarms1.52.02.51.31.4-1.4-1.51.41.41.41.51.51.41.5-1.51.5-1.5-1.51.41.4-1.61.3-0.8
Reaction time num false alarms AUC2.23.03.41.61.8-1.7-1.81.71.71.71.81.81.81.8-1.81.8-1.9-1.81.81.7-1.81.7-0.9
Reaction time trials correct on left1.72.44.9-1.8-1.61.81.5-1.6-1.7-1.7-1.5-1.5-1.3-1.61.5-1.41.41.7-1.6-1.70.8-0.72.2
Reaction time trials on left1.41.94.4-1.6-1.41.71.3-1.4-1.5-1.5-1.3-1.3-1.2-1.41.3-1.31.21.5-1.4-1.60.7-0.62.1
Reaction time mean0.71.02.40.91.0-1.0-1.01.11.01.01.00.90.91.0-0.90.9-0.9-1.00.90.9-0.70.6-1.5
Reaction time mean AUC0.40.51.80.60.7-0.7-0.70.80.70.70.70.70.70.7-0.70.7-0.7-0.80.70.6-0.50.4-1.3
Median of all reaction times0.00.00.5-0.1-0.10.10.10.1-0.1-0.1-0.1-0.1-0.1-0.00.1-0.10.10.1-0.1-0.20.3-0.2-0.7
Reaction time omissions9.613.114.43.33.8-3.5-3.83.73.73.73.83.83.83.7-3.73.8-3.8-3.63.63.6-3.73.2-2.7
Reaction time false alarm rate2.63.74.32.02.0-2.1-2.01.92.02.02.02.01.82.0-2.01.9-1.9-2.12.02.0-1.71.5-1.7
Reaction time premature initiation rate6.78.911.13.23.1-3.1-3.03.23.23.23.03.03.03.1-3.03.0-2.9-2.92.93.0-2.31.9-3.3
Reaction time premature initiations2.94.14.92.02.1-2.0-2.12.22.12.12.12.12.12.1-2.12.1-2.0-1.91.92.0-1.81.5-2.0
Std. dev. reaction times6.08.49.02.73.0-3.0-3.03.03.03.03.03.03.03.0-3.03.0-3.0-3.02.92.9-2.82.3-2.6
Reaction time trials completed1.41.94.4-1.6-1.41.71.3-1.4-1.5-1.5-1.3-1.3-1.2-1.41.3-1.31.21.5-1.4-1.60.7-0.62.1
Reaction time trials AUC2.13.06.0-2.0-1.82.01.7-1.7-1.9-1.9-1.7-1.7-1.5-1.81.7-1.61.61.8-1.7-1.91.0-0.82.4
Run reversals in cocaine runway, females0.00.00.1-0.30.10.30.00.10.10.10.00.00.1-0.0-0.00.1-0.0-0.0-0.00.10.2-0.20.3
Run reversals in cocaine runway, males1.51.41.71.11.2-1.2-1.21.21.21.21.21.21.21.2-1.21.2-1.2-1.21.11.2-1.30.9-1.0
Latency to leave start box in cocaine runway0.00.00.1-0.20.00.1-0.10.10.10.10.10.10.00.1-0.10.1-0.1-0.1-0.00.10.2-0.1-0.3
Latency to leave start box in cocaine runway, F1.71.82.11.31.4-1.4-1.41.41.31.31.41.41.41.4-1.41.4-1.4-1.41.41.3-1.21.2-1.1
Latency to leave start box in cocaine runway, M2.12.13.0-1.7-1.51.61.4-1.4-1.4-1.4-1.4-1.4-1.5-1.41.4-1.41.51.4-1.5-1.41.5-1.50.7
Std. dev. time between licks in bursts1.01.31.81.31.1-1.1-1.21.21.11.11.21.11.11.2-1.11.1-1.1-1.11.11.0-0.80.9-1.3
Total sessions with >9 infusions1.21.35.71.41.1-1.2-1.11.21.31.31.11.01.01.2-1.00.9-0.9-0.90.80.9-0.70.1-2.4
Short access day 1 total inactive lever presses1.71.83.11.81.3-1.5-1.31.41.41.41.31.31.31.4-1.31.3-1.3-1.41.31.3-1.10.8-1.7
Short access day 10 total inactive lever presses0.30.30.70.60.5-0.5-0.40.40.40.40.50.50.50.4-0.50.6-0.6-0.60.80.6-0.40.90.5
Short access day 1 total infusions0.20.21.40.80.3-0.5-0.30.40.40.40.30.20.30.3-0.20.2-0.2-0.20.20.2-0.2-0.1-1.2
Short access day 10 total infusions1.11.33.81.31.1-1.2-1.11.21.31.31.11.01.11.2-1.01.0-1.0-1.00.81.1-0.80.3-1.9
Short access total infusions0.80.94.41.20.8-1.0-0.91.01.01.00.80.80.80.9-0.80.7-0.7-0.70.50.7-0.5-0.1-2.1
Short access day 1 locomotion0.20.20.90.70.4-0.5-0.40.50.50.50.40.40.40.4-0.40.3-0.3-0.30.30.5-0.0-0.1-1.0
Short access day 10 total locomotion0.10.20.30.20.4-0.2-0.40.40.40.40.40.40.50.4-0.40.4-0.4-0.50.40.5-0.30.30.0
Short access total locomotion0.50.50.90.90.8-0.7-0.70.80.90.90.70.70.80.7-0.70.7-0.7-0.70.60.7-0.30.3-1.0
One hour access (0.3 mA shock)0.40.52.20.90.6-0.7-0.70.70.80.80.60.60.60.7-0.60.5-0.5-0.50.50.5-0.10.1-1.5
Compulsive drug intake1.11.11.4-1.1-1.11.01.1-1.2-1.2-1.2-1.0-1.0-1.1-1.11.0-1.01.00.9-1.0-0.90.8-0.71.2
One hour access (shock baseline)0.30.42.30.90.6-0.7-0.60.70.70.70.50.50.50.6-0.50.4-0.4-0.30.40.20.1-0.1-1.5
Social response proportion0.20.20.60.80.4-0.6-0.40.40.50.50.40.40.40.4-0.40.3-0.3-0.40.40.4-0.20.1-0.7
Social responses7.79.910.93.33.2-3.3-3.23.33.33.33.23.23.23.3-3.23.2-3.2-3.33.13.3-2.62.3-2.9
Social time0.00.00.00.10.2-0.2-0.00.10.20.20.00.00.2-0.0-0.00.1-0.0-0.10.10.1-0.20.00.0
Soleus weight0.61.82.3-1.5-1.31.51.3-1.3-1.3-1.3-1.3-1.3-1.4-1.31.3-1.31.31.3-1.3-1.41.5-1.21.0
Bone: stiffness17.026.828.7-5.3-5.35.25.3-5.3-5.3-5.3-5.3-5.3-5.3-5.35.3-5.35.25.3-5.1-5.45.3-4.24.2
Tibialis anterior weight0.82.87.8-1.0-1.61.61.7-1.4-1.4-1.4-1.7-1.7-1.9-1.51.7-1.81.91.5-1.7-1.32.8-2.3-0.7
Time to tail flick, vehicle, before self-admin0.90.91.40.71.0-1.0-0.90.70.90.91.01.01.00.9-1.01.0-1.0-1.01.01.1-1.21.0-0.3
Time to tail flick, vehicle, after self-admin0.20.20.3-0.1-0.40.40.5-0.4-0.5-0.5-0.5-0.5-0.4-0.50.5-0.50.50.5-0.3-0.50.5-0.00.5
Time to tail flick, test, before self-admin0.30.30.80.40.7-0.5-0.50.50.60.60.50.60.70.5-0.50.6-0.6-0.50.70.5-0.90.7-0.0
Time to tail flick, test, after self-admin0.20.20.3-0.4-0.40.40.4-0.5-0.4-0.4-0.4-0.4-0.4-0.50.4-0.40.40.5-0.3-0.50.5-0.20.4
Delta time to tail flick, vehicle, before/after SA0.40.40.6-0.3-0.60.60.6-0.4-0.6-0.6-0.6-0.6-0.6-0.60.6-0.70.70.6-0.6-0.70.8-0.40.3
Delta time to tail flick, test, before/after SA0.20.20.4-0.3-0.50.40.4-0.4-0.4-0.4-0.4-0.4-0.5-0.30.4-0.40.40.4-0.5-0.30.6-0.40.1
Tibia length7.220.226.5-4.3-4.64.44.6-4.4-4.5-4.5-4.6-4.6-4.8-4.54.6-4.74.74.6-4.5-4.75.1-4.12.4
Ambulatory time before self-admin4.04.25.12.32.1-2.2-2.02.12.02.02.12.12.12.0-2.12.1-2.1-2.22.22.1-2.11.8-1.3
Ambulatory time after self-admin1.82.02.61.61.5-1.5-1.41.41.41.41.41.41.41.5-1.41.4-1.4-1.41.51.3-1.41.2-1.3
Bone: tissue strength1.21.13.3-0.9-1.01.01.1-1.2-1.2-1.2-1.1-1.1-1.0-1.21.1-1.01.01.0-0.8-1.10.8-0.31.8
Total heroin consumption1.82.12.5-1.4-1.41.51.5-1.6-1.4-1.4-1.5-1.5-1.4-1.51.5-1.51.51.5-1.5-1.41.6-1.31.1
Bone: trabecular number6.810.615.2-3.9-3.43.33.3-3.3-3.4-3.4-3.2-3.2-3.2-3.33.2-3.23.23.3-3.2-3.33.0-2.43.1
Bone: trabecular spacing2.43.24.82.21.9-1.8-1.81.81.91.91.81.81.81.8-1.81.8-1.7-1.71.71.7-1.61.2-1.8
Bone: trabecular thickness0.10.10.10.10.3-0.2-0.40.40.30.30.40.30.30.4-0.30.3-0.3-0.30.20.3-0.30.3-0.2
Bone: trabecular tissue density0.10.10.30.20.3-0.2-0.30.20.20.20.30.30.30.3-0.30.3-0.3-0.20.30.2-0.20.50.0
Water consumed over 24 hours0.00.00.2-0.5-0.20.30.1-0.2-0.2-0.2-0.1-0.1-0.1-0.10.1-0.10.10.3-0.2-0.30.00.00.5
Number of responses in last shaping day0.10.10.60.7-0.0-0.20.1-0.0-0.0-0.0-0.1-0.10.0-0.00.1-0.20.10.10.0-0.10.6-0.1-0.7