Hub : Traits

Reaction time omissions

Number of times that the rat failed to make a response within 3 sec of the onset of the imperative stimulus in the last three 18-minute sessions for males and females [n]

Tags: Behavior · Reaction time

Project: p50_david_dietz

1 loci · 1 genes with independent associations · 1 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	2	124071278	125075599	1	1	3.41e-08	2.57e-07	1e+00	RGD1359508

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	3.55	1	0	0	1	1.56e-04	RGD1359508
Body weight	4	1	0	0	1	4.48e-05	RGD1359508
Extensor digitorum longus weight	1.73	1	0	0	0	1.00e+00	RGD1359508
Reaction time number correct	4.66	1	0	0	0	1.00e+00	RGD1359508
Reaction time mean minus median	12.84	1	0	0	1	2.98e-06	RGD1359508
Reaction time mean minus median AUC	9.18	1	0	0	1	3.88e-05	RGD1359508
Reaction time trials correct on left	4.66	1	0	0	0	1.00e+00	RGD1359508
Reaction time mean	11.62	1	0	0	1	6.41e-07	RGD1359508
Reaction time mean AUC	12.66	1	0	0	1	1.23e-08	RGD1359508
Median of all reaction times	7.75	1	0	0	1	1.43e-07	RGD1359508
Reaction time premature initiations	5.96	1	0	0	-1	1.93e-04	RGD1359508
Std. dev. reaction times	15.68	1	0	0	1	4.84e-06	RGD1359508
Condit. Reinf. active minus inactive responses	5.72	1	0	0	0	1.00e+00	RGD1359508
Condit. Reinf. active-inactive response ratio	9.99	1	0	0	1	2.39e-06	RGD1359508
Bone: post-yield work	5.85	1	0	0	1	1.31e-03	RGD1359508
Delay discount exponential model param	6.3	1	0	0	0	1.00e+00	RGD1359508

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.33
Adipose	alternative TSS	0	0	1.31
Adipose	gene expression	0	0	1.33
Adipose	isoform ratio	0	0	1.36
Adipose	intron excision ratio	0	0	1.27
Adipose	mRNA stability	0	0	1.3
BLA	alternative polyA	0	0	1.39
BLA	alternative TSS	0	0	1.15
BLA	gene expression	1	0	1.37
BLA	isoform ratio	0	0	1.4
BLA	intron excision ratio	0	0	1.37
BLA	mRNA stability	1	0	1.39
Brain	alternative polyA	0	0	1.31
Brain	alternative TSS	0	0	1.5
Brain	gene expression	1	0	1.36
Brain	isoform ratio	0	0	1.47
Brain	intron excision ratio	1	0	1.38
Brain	mRNA stability	0	0	1.34
Eye	alternative polyA	0	0	1.56
Eye	alternative TSS	0	0	1.5
Eye	gene expression	0	0	1.45
Eye	isoform ratio	0	0	1.35
Eye	intron excision ratio	0	0	1.42
Eye	mRNA stability	0	0	1.55
IL	alternative polyA	0	0	1.66
IL	alternative TSS	0	0	1.19
IL	gene expression	0	0	1.33
IL	isoform ratio	0	0	1.47
IL	intron excision ratio	0	0	1.5
IL	mRNA stability	0	0	1.35
LHb	alternative polyA	0	0	1.34
LHb	alternative TSS	0	0	1.48
LHb	gene expression	0	0	1.37
LHb	isoform ratio	0	0	1.49
LHb	intron excision ratio	0	0	1.49
LHb	mRNA stability	0	0	1.26
Liver	alternative polyA	0	0	1.28
Liver	alternative TSS	0	0	1.29
Liver	gene expression	0	0	1.3
Liver	isoform ratio	0	0	1.32
Liver	intron excision ratio	0	0	1.3
Liver	mRNA stability	0	0	1.3
NAcc	alternative polyA	0	0	1.39
NAcc	alternative TSS	0	0	1.19
NAcc	gene expression	1	0	1.33
NAcc	isoform ratio	0	0	1.37
NAcc	intron excision ratio	0	0	1.33
NAcc	mRNA stability	0	0	1.33
OFC	alternative polyA	0	0	1.49
OFC	alternative TSS	0	0	1.48
OFC	gene expression	0	0	1.36
OFC	isoform ratio	0	0	1.49
OFC	intron excision ratio	0	0	1.52
OFC	mRNA stability	0	0	1.29
PL	alternative polyA	0	0	1.31
PL	alternative TSS	0	0	1.28
PL	gene expression	0	0	1.33
PL	isoform ratio	0	0	1.46
PL	intron excision ratio	0	0	1.39
PL	mRNA stability	0	0	1.36