Hub : Genes

Cd99

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Cd99 0.06 0.05 8.5e-03 0.01 0.01 0.02 0.01 6.3e-02 1.0e-02 3.8e-03 6.4e-02
2 Liver isoform ratio XM_039099056.1 0.08 0.06 1.5e-03 0 0.01 0.02 0 3.3e-01 8.7e-03 3.4e-03 2.3e-01
3 Adipose isoform ratio XM_039099056.1 0.04 0.04 1.3e-03 0.03 0.03 0.03 0.03 2.7e-04 5.0e-04 5.6e-04 2.8e-04
4 Liver intron excision ratio chr20_54421146_54421589 0.14 0.09 6.2e-09 0.08 0.08 0.08 0.08 3.4e-09 3.8e-09 8.1e-09 5.1e-09
5 PL isoform ratio NM_001100804.1 0.02 0.02 6.1e-03 0.01 0.01 0.01 0.01 1.2e-02 2.4e-02 1.2e-02 2.5e-02
6 BLA gene expression Cd99 0.07 0.07 2.2e-03 0.04 0.04 0.05 0.04 1.9e-03 1.9e-03 1.6e-03 2.0e-03
7 Adipose isoform ratio XR_005497336.1 0.08 0.06 7.0e-11 0.06 0.1 0.1 0.1 1.4e-07 5.4e-11 3.4e-11 4.9e-11
8 Adipose gene expression Cd99 0.16 0.1 0.0e+00 0.17 0.17 0.17 0.17 2.2e-18 2.1e-18 4.2e-18 4.6e-18
9 Adipose mRNA stability Cd99 0.2 0.12 0.0e+00 0.22 0.22 0.22 0.22 5.9e-24 8.7e-24 5.8e-24 2.8e-24
10 Brain intron excision ratio chr20_54420269_54420848 0.11 0.1 5.4e-09 0.09 0.1 0.09 0.1 9.8e-09 1.3e-09 1.2e-08 1.3e-09
11 Brain isoform ratio XR_005497336.1 0.1 0.1 3.4e-08 0.07 0.09 0.07 0.09 6.9e-07 2.8e-08 3.0e-07 2.0e-08
12 Brain intron excision ratio chr20_54419212_54420848 0.06 0.06 1.7e-05 0.03 0.04 0.01 0.04 1.2e-03 1.7e-04 6.1e-02 1.3e-04
13 Brain isoform ratio NM_001100804.1 0.04 0.04 1.0e-03 0.02 0.03 0.02 0.03 2.8e-03 1.6e-03 3.5e-03 1.2e-03
14 BLA isoform ratio XR_005497336.1 0.09 0.09 4.3e-04 0.04 0.03 0.04 0.04 2.0e-03 6.4e-03 4.3e-03 5.2e-03
15 BLA intron excision ratio chr20_54420269_54420848 0.12 0.11 2.9e-05 0.09 0.07 0.08 0.08 2.4e-05 7.6e-05 6.4e-05 4.1e-05
16 PL gene expression Cd99 0.11 0.15 2.9e-04 0.03 0.03 0.03 0.03 7.7e-04 2.8e-04 6.9e-04 1.1e-04
17 PL isoform ratio XR_005497336.1 0.03 0.03 1.5e-03 0.02 0.02 0.01 0.02 2.9e-03 2.9e-03 7.9e-03 1.8e-03
18 PL intron excision ratio chr20_54419212_54420848 0.04 0.04 3.4e-04 0.02 0.02 0.02 0.03 1.1e-03 1.3e-03 2.2e-03 8.4e-04
19 PL intron excision ratio chr20_54420269_54420848 0.05 0.05 1.3e-05 0.03 0.03 0.03 0.04 1.2e-04 2.1e-04 4.0e-04 9.7e-05
20 BLA intron excision ratio chr20_54419212_54420848 0.08 0.08 5.7e-04 0.07 0.06 0.06 0.06 1.8e-04 5.5e-04 4.3e-04 2.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.20.30.40.30.6-0.50.5-0.50.50.50.50.5-0.5-0.50.50.50.50.5-0.5-0.50.5-0.5-0.3
Area under the delay curve5.86.26.2-2.5-2.52.5-2.52.5-2.5-2.5-2.5-2.52.52.5-2.5-2.5-2.5-2.52.52.5-2.52.52.5
BMI with tail1.13.636.56.0-0.7-1.81.8-1.81.51.51.61.3-1.2-1.21.21.21.21.2-1.2-1.21.2-1.2-0.9
BMI without tail0.20.56.22.5-0.4-0.60.6-0.60.50.50.50.4-0.4-0.40.40.40.40.4-0.4-0.40.4-0.4-0.1
Body weight1.45.832.45.70.6-2.52.5-2.52.32.22.32.1-2.0-2.02.02.02.02.0-2.0-2.02.0-2.0-1.9
Weight adjusted by age0.60.70.80.80.8-0.80.8-0.80.80.80.80.8-0.8-0.80.80.80.80.8-0.8-0.80.8-0.8-0.9
Bone surface0.91.72.11.51.2-1.31.3-1.31.31.31.21.3-1.3-1.31.31.31.31.3-1.3-1.31.3-1.3-1.0
Bone volume0.50.91.11.10.9-1.01.0-1.01.01.00.91.0-1.0-1.01.01.01.01.0-1.0-1.01.0-1.0-0.7
Breakpoint value in progressive ratio session1.82.02.0-1.4-1.41.4-1.41.4-1.4-1.4-1.4-1.41.41.4-1.4-1.4-1.4-1.41.41.4-1.41.41.4
Number of licking bursts0.80.90.91.01.0-1.01.0-1.01.01.01.01.0-1.0-1.01.01.01.01.0-1.0-1.01.0-1.0-1.0
Context. condit. distance diff. score2.32.85.4-0.1-2.31.5-1.51.5-1.6-1.6-1.6-1.71.71.7-1.7-1.7-1.7-1.71.71.7-1.71.71.7
Locomotion velocity, session 10.70.80.80.90.9-0.90.9-0.90.90.90.90.9-0.9-0.90.90.90.90.9-0.9-0.90.9-0.9-0.9
Locomotion distance, session 10.00.00.00.10.1-0.10.1-0.10.10.10.10.1-0.1-0.10.10.10.10.1-0.1-0.10.1-0.1-0.1
Locomotion velocity, session 21.21.48.32.90.3-1.21.2-1.21.11.11.11.0-1.0-1.01.01.01.01.0-1.0-1.01.0-1.0-1.0
Locomotion distance, session 22.33.29.53.11.2-1.91.9-1.91.81.81.81.7-1.7-1.71.71.71.71.7-1.7-1.71.7-1.7-1.7
Locomotion velocity, session 30.20.34.22.0-0.5-0.40.4-0.40.30.30.40.2-0.2-0.20.20.20.20.2-0.2-0.20.2-0.2-0.2
Locomotion distance, session 30.20.21.81.3-1.00.2-0.20.2-0.3-0.3-0.2-0.30.40.4-0.4-0.4-0.4-0.40.40.4-0.40.40.4
Stereotopy head waving bouts, day 30.00.00.10.2-0.30.2-0.20.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.2-0.20.20.2-0.20.20.2
Stereotopy head waving duration, day 30.10.10.2-0.4-0.30.4-0.40.4-0.3-0.3-0.3-0.30.30.3-0.3-0.3-0.3-0.30.30.3-0.30.30.3
Locomotion velocity, session 70.60.72.00.7-1.40.7-0.70.7-0.8-0.8-0.7-0.80.90.9-0.9-0.9-0.9-0.90.90.9-0.90.90.9
Locomotion distance, session 70.91.16.42.50.3-1.11.1-1.11.01.01.00.9-0.9-0.90.90.90.90.9-0.9-0.90.9-0.9-0.9
Stereotopy head waving bouts, day 71.61.85.51.4-2.31.0-1.01.0-1.2-1.2-1.1-1.31.31.3-1.3-1.3-1.3-1.31.31.3-1.31.31.3
Stereotopy head waving duration, day 71.31.65.72.0-2.40.8-0.80.8-1.0-1.0-0.9-1.11.21.2-1.2-1.2-1.2-1.21.21.2-1.21.21.2
Locomotion velocity, session 80.40.51.70.9-1.30.5-0.50.5-0.6-0.6-0.6-0.70.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.7
Locomotion distance, session 80.40.64.22.0-1.60.3-0.30.3-0.5-0.5-0.4-0.60.60.6-0.6-0.6-0.6-0.60.60.6-0.60.60.6
Degree of sensitization distance1.51.52.20.71.5-1.21.2-1.21.21.21.21.2-1.3-1.31.31.31.31.3-1.3-1.31.3-1.3-1.3
Degree of sensitization stereotypy1.21.34.01.3-2.00.8-0.80.8-1.0-1.0-0.9-1.11.11.1-1.1-1.1-1.1-1.11.11.1-1.11.11.1
Conditioned locomotion0.00.00.5-0.70.30.0-0.00.00.00.0-0.00.0-0.1-0.10.10.10.10.1-0.1-0.10.1-0.1-0.0
Cocaine response after cond. corrected0.70.71.40.11.2-0.80.8-0.80.90.90.70.9-0.9-0.90.90.90.90.9-0.9-0.90.9-0.9-0.7
Cocaine response after cond. not corrected1.92.03.70.21.9-1.31.3-1.31.41.41.31.5-1.5-1.51.51.51.51.5-1.5-1.51.5-1.5-1.4
Cocaine response before conditioning1.01.22.7-0.31.6-0.90.9-0.91.01.01.11.1-1.1-1.11.11.11.11.1-1.1-1.11.1-1.1-1.3
Saline control response1.01.34.0-1.42.0-0.80.8-0.80.90.91.01.0-1.1-1.11.11.11.11.1-1.1-1.11.1-1.1-1.3
Bone: connectivity density0.61.02.9-0.91.7-0.80.8-0.80.90.90.81.0-1.0-1.01.01.01.01.0-1.0-1.01.0-1.0-0.9
Bone: cortical apparent density2.93.85.2-1.2-2.31.9-1.91.9-1.9-1.9-1.9-2.02.02.0-2.0-2.0-2.0-2.02.02.0-2.02.02.0
Bone: cortical area0.20.34.92.2-0.6-0.40.4-0.40.30.30.30.2-0.2-0.20.20.20.20.2-0.2-0.20.2-0.2-0.1
Bone: cortical porosity0.70.88.83.0-0.4-0.80.8-0.80.70.70.70.6-0.5-0.50.50.50.50.5-0.5-0.50.5-0.5-0.6
Bone: cortical porosity0.80.95.32.30.2-1.01.0-1.00.90.90.90.8-0.8-0.80.80.80.80.8-0.8-0.80.8-0.8-0.7
Bone: cortical thickness0.10.20.6-0.7-0.30.4-0.40.4-0.4-0.4-0.4-0.40.40.4-0.4-0.4-0.4-0.40.40.4-0.40.40.3
Bone: cortical thickness0.10.11.71.3-0.4-0.20.2-0.20.10.10.20.1-0.0-0.00.00.00.00.0-0.0-0.00.0-0.0-0.3
Bone: cortical tissue density3.04.05.1-1.4-2.32.0-2.02.0-2.0-2.0-2.0-2.02.02.0-2.0-2.0-2.0-2.02.02.0-2.02.02.0
Condit. Reinf. active minus inactive responses0.20.20.6-0.8-0.30.5-0.50.5-0.5-0.5-0.5-0.50.50.5-0.5-0.5-0.5-0.50.50.5-0.50.50.5
Condit. Reinf. active-inactive response ratio0.10.11.2-1.10.40.1-0.10.1-0.0-0.0-0.1-0.0-0.0-0.00.00.00.00.0-0.0-0.00.0-0.0-0.0
Condit. Reinf. active responses0.10.10.2-0.1-0.40.3-0.30.3-0.4-0.4-0.3-0.40.40.4-0.4-0.4-0.4-0.40.40.4-0.40.40.4
Condit. Reinf. inactive responses0.10.10.70.8-0.50.0-0.00.0-0.1-0.1-0.1-0.10.20.2-0.2-0.2-0.2-0.20.20.2-0.20.20.2
Incentive salience index mean0.00.10.10.1-0.40.2-0.20.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.2-0.20.20.2-0.20.20.2
Condit. Reinf. lever presses0.00.00.40.7-0.50.1-0.10.1-0.1-0.1-0.1-0.10.20.2-0.2-0.2-0.2-0.20.20.2-0.20.20.2
Condit. Reinf. active minus inactive responses0.10.20.3-0.00.5-0.30.3-0.30.40.40.50.4-0.4-0.40.40.40.40.4-0.4-0.40.4-0.4-0.6
Condit. Reinf. active-inactive response ratio2.32.45.2-0.32.3-1.41.4-1.41.51.51.41.6-1.6-1.61.61.61.61.6-1.6-1.61.6-1.6-1.5
Condit. Reinf. active responses0.30.40.6-0.3-0.80.6-0.60.6-0.6-0.6-0.5-0.70.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.4
Condit. Reinf. inactive responses3.13.86.3-0.7-2.51.9-1.91.9-2.0-2.0-1.7-2.02.02.0-2.0-2.0-2.0-2.02.02.0-2.02.01.7
Condit. Reinf. lever presses0.10.10.6-0.7-0.00.3-0.30.3-0.2-0.2-0.1-0.20.20.2-0.2-0.2-0.2-0.20.20.2-0.20.2-0.0
Condit. Reinf. lever reinforcers received0.50.80.9-0.7-1.00.9-0.90.9-0.9-0.9-0.7-0.90.90.9-0.9-0.9-0.9-0.90.90.9-0.90.90.6
Conditioned reinforcement - actives0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Conditioned reinforcement - inactives0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Conditioned locomotion0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Patch foraging indifference point 0 sec0.40.68.0-2.81.3-0.00.0-0.00.20.20.10.3-0.4-0.40.40.40.40.4-0.4-0.40.4-0.4-0.5
Patch foraging indifference point AUC2.52.88.8-3.0-1.01.7-1.71.7-1.7-1.7-1.7-1.61.61.6-1.6-1.6-1.6-1.61.61.6-1.61.61.5
Delay disc. indifference point, 0s delay0.40.50.5-0.7-0.70.7-0.70.7-0.7-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.7
Delay disc. indifference point, 16s delay1.41.51.5-1.2-1.21.2-1.21.2-1.2-1.2-1.2-1.21.21.2-1.2-1.2-1.2-1.21.21.2-1.21.21.2
Delay disc. indifference point, 2s delay4.95.55.5-2.3-2.32.3-2.32.3-2.3-2.3-2.3-2.32.32.3-2.3-2.3-2.3-2.32.32.3-2.32.32.3
Delay disc. indifference point, 24s delay3.02.92.9-1.7-1.71.7-1.71.7-1.7-1.7-1.7-1.71.71.7-1.7-1.7-1.7-1.71.71.7-1.71.71.7
Delay disc. indifference point, 4s delay7.37.77.7-2.8-2.82.8-2.82.8-2.8-2.8-2.8-2.82.82.8-2.8-2.8-2.8-2.82.82.8-2.82.82.8
Delay disc. indifference point, 8s delay5.15.35.3-2.3-2.32.3-2.32.3-2.3-2.3-2.3-2.32.32.3-2.3-2.3-2.3-2.32.32.3-2.32.32.3
Indifference point function ln k0.81.23.21.80.8-1.11.1-1.11.11.11.01.1-1.0-1.01.01.01.01.0-1.0-1.01.0-1.0-0.9
Indifference point function log k0.81.23.21.80.8-1.11.1-1.11.11.11.01.1-1.0-1.01.01.01.01.0-1.0-1.01.0-1.0-0.9
Patch foraging total patch changes 0 sec0.40.77.6-2.81.5-0.10.1-0.10.30.30.30.5-0.5-0.50.50.50.50.5-0.5-0.50.5-0.5-0.7
Patch foraging total patch changes 12 sec0.91.17.0-2.7-0.41.1-1.11.1-1.0-1.0-1.0-0.90.90.9-0.9-0.9-0.9-0.90.90.9-0.90.90.7
Patch foraging total patch changes 18 sec0.30.46.6-2.60.60.5-0.50.5-0.3-0.3-0.3-0.20.20.2-0.2-0.2-0.2-0.20.20.2-0.20.2-0.0
Patch foraging total patch changes 24 sec0.20.34.8-2.20.70.3-0.30.3-0.2-0.2-0.2-0.10.00.0-0.0-0.0-0.0-0.00.00.0-0.00.0-0.1
Patch foraging total patch changes 6 sec0.10.11.8-1.30.10.3-0.30.3-0.2-0.2-0.1-0.10.10.1-0.1-0.1-0.1-0.10.10.1-0.10.1-0.1
Patch foraging time to switch 0 sec0.40.64.92.2-0.0-0.70.7-0.70.60.60.70.6-0.5-0.50.50.50.50.5-0.5-0.50.5-0.5-0.5
Patch foraging water rate 0 sec0.40.72.1-1.5-0.60.8-0.80.8-0.8-0.8-0.9-0.80.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.8
Patch foraging water rate 12 sec0.10.21.0-1.0-0.30.5-0.50.5-0.4-0.4-0.5-0.40.40.4-0.4-0.4-0.4-0.40.40.4-0.40.40.4
Patch foraging water rate 18 sec0.00.00.40.6-0.50.0-0.00.0-0.1-0.1-0.0-0.10.10.1-0.1-0.1-0.1-0.10.10.1-0.10.10.1
Patch foraging water rate 24 sec0.30.50.50.70.6-0.70.7-0.70.70.70.60.7-0.7-0.70.70.70.70.7-0.7-0.70.7-0.7-0.6
Patch foraging water rate 6 sec0.00.00.20.4-0.2-0.10.1-0.10.10.10.10.1-0.0-0.00.00.00.00.0-0.0-0.00.0-0.0-0.0
Seeking ratio, delayed vs. immediate footshock0.30.30.3-0.6-0.60.6-0.60.6-0.6-0.6-0.6-0.60.60.6-0.6-0.6-0.6-0.60.60.6-0.60.60.6
Distance traveled before self-admin0.91.01.0-1.0-1.01.0-1.01.0-1.0-1.0-1.0-1.01.01.0-1.0-1.0-1.0-1.01.01.0-1.01.01.0
Distance traveled after self-admin1.21.31.4-1.2-1.21.2-1.21.2-1.2-1.2-1.2-1.21.21.2-1.2-1.2-1.2-1.21.21.2-1.21.21.2
Extensor digitorum longus weight0.31.36.62.6-2.30.6-0.60.6-0.8-0.8-0.6-0.91.01.0-1.0-1.0-1.0-1.01.01.0-1.01.00.9
Bone: elastic displacement0.80.93.0-1.7-0.61.0-1.01.0-0.9-0.9-0.9-0.90.90.9-0.9-0.9-0.9-0.90.90.9-0.90.90.9
Bone: elastic work0.30.45.6-2.41.20.0-0.00.00.10.10.00.2-0.3-0.30.30.30.30.3-0.3-0.30.3-0.3-0.1
Bone: endosteal estimation0.71.55.72.40.6-1.31.3-1.31.21.21.21.1-1.1-1.11.11.11.11.1-1.1-1.11.1-1.1-1.0
Bone: endosteal perimeter0.71.522.94.8-1.3-0.80.8-0.80.60.60.70.4-0.3-0.30.30.30.30.3-0.3-0.30.3-0.3-0.1
Epididymis fat weight0.10.20.30.20.5-0.50.5-0.50.50.50.50.5-0.5-0.50.50.50.50.5-0.5-0.50.5-0.5-0.3
Delta time in closed arm before/after self-admin0.70.60.60.80.8-0.80.8-0.80.80.80.80.8-0.8-0.80.80.80.80.8-0.8-0.80.8-0.8-0.8
Delta time in open arm before/after self-admin2.72.62.6-1.6-1.61.6-1.61.6-1.6-1.6-1.6-1.61.61.6-1.6-1.6-1.6-1.61.61.6-1.61.61.6
Diff in mean of infusions in LGA sessions0.30.40.4-0.6-0.60.6-0.60.6-0.6-0.6-0.6-0.60.60.6-0.6-0.6-0.6-0.60.60.6-0.60.60.6
Delay discount exponential model param6.87.27.22.72.7-2.72.7-2.72.72.72.72.7-2.7-2.72.72.72.72.7-2.7-2.72.7-2.7-2.7
Extinction: sum of active levers before priming0.20.20.20.50.5-0.50.5-0.50.50.50.50.5-0.5-0.50.50.50.50.5-0.5-0.50.5-0.5-0.5
Active lever presses in extinction session 60.60.60.6-0.8-0.80.8-0.80.8-0.8-0.8-0.8-0.80.80.8-0.8-0.8-0.8-0.80.80.8-0.80.80.8
Bone: final force0.00.10.30.60.1-0.30.3-0.30.20.20.20.2-0.2-0.20.20.20.20.2-0.2-0.20.2-0.2-0.3
Bone: final moment0.10.20.50.70.3-0.40.4-0.40.40.40.40.4-0.4-0.40.40.40.40.4-0.4-0.40.4-0.4-0.5
Food consumed during 24 hour testing period1.01.21.21.11.1-1.11.1-1.11.11.11.01.1-1.1-1.11.11.11.11.1-1.1-1.11.1-1.1-1.0
Glucose0.30.50.7-0.9-0.60.7-0.70.7-0.7-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.7
Heart weight2.13.05.10.12.3-1.61.6-1.61.71.71.61.8-1.8-1.81.81.81.81.8-1.8-1.81.8-1.8-1.5
Delay discount hyperbolic model param7.57.98.02.82.8-2.82.8-2.82.82.82.82.8-2.8-2.82.82.82.82.8-2.8-2.82.8-2.8-2.8
Intermittent access intake day 1-15 change0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intermittent access intake escalation0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intermittent access intake escalation 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intermitt. access day 1 inactive lever presses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intermitt. access day 15 inactive lever presses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intermitt. access escalation Index0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intermittent access day 1 total infusions0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intermittent access day 15 total infusions0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intermittent access terminal intake (last 3 days)0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intermittent access total infusions0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intermittent access day 1 locomotion0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intermittent access day 15 total locomotion0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intermittent access total locomotion0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intermittent access standard deviation0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Left kidney weight0.72.020.74.6-0.4-1.31.3-1.31.11.11.21.0-0.9-0.90.90.90.90.9-0.9-0.90.9-0.9-0.8
Right kidney weight0.61.817.44.2-0.3-1.31.3-1.31.11.11.21.0-0.9-0.90.90.90.90.9-0.9-0.90.9-0.9-0.7
Cocaine induced anxiety0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Post-drug Anxiety0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Baseline Anxiety0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Tail length0.20.51.5-0.61.2-0.60.6-0.60.60.60.60.7-0.7-0.70.70.70.70.7-0.7-0.70.7-0.7-0.7
Length with tail0.51.92.40.91.6-1.31.3-1.31.41.41.31.4-1.4-1.41.41.41.41.4-1.4-1.41.4-1.4-1.5
Length without tail0.71.41.80.71.4-1.21.2-1.21.21.21.11.2-1.2-1.21.21.21.21.2-1.2-1.21.2-1.2-1.3
Times rat made contact with spout1.82.12.11.51.5-1.51.5-1.51.51.51.51.5-1.5-1.51.51.51.51.5-1.5-1.51.5-1.5-1.5
Lifetime Intake0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Liver weight, left0.81.38.83.00.1-1.11.1-1.11.01.01.10.9-0.9-0.90.90.90.90.9-0.9-0.90.9-0.9-0.9
Liver weight, right1.72.820.44.50.1-1.71.7-1.71.51.51.51.4-1.3-1.31.31.31.31.3-1.3-1.31.3-1.3-1.2
Locomotor activity0.30.51.4-0.91.2-0.50.5-0.50.60.60.60.7-0.7-0.70.70.70.70.7-0.7-0.70.7-0.7-0.7
Locomotor testing distance0.20.31.0-1.00.9-0.30.3-0.30.40.40.40.4-0.5-0.50.50.50.50.5-0.5-0.50.5-0.5-0.5
Locomotor testing rearing0.10.22.4-1.50.8-0.10.1-0.10.20.20.20.2-0.3-0.30.30.30.30.3-0.3-0.30.3-0.3-0.4
Locomotion in novel chamber0.10.10.1-0.3-0.30.3-0.30.3-0.3-0.3-0.3-0.30.30.3-0.3-0.3-0.3-0.30.30.3-0.30.30.3
Locomotion in novel chamber post-restriction0.30.30.30.60.6-0.60.6-0.60.60.60.60.6-0.6-0.60.60.60.60.6-0.6-0.60.6-0.6-0.6
Fecal boli incidents, locomotor time 10.00.00.0-0.0-0.00.0-0.00.0-0.0-0.0-0.0-0.00.00.0-0.0-0.0-0.0-0.00.00.0-0.00.00.0
Change in fecal boli incidents, locomotor task2.22.12.1-1.4-1.41.4-1.41.4-1.4-1.4-1.5-1.41.41.4-1.4-1.4-1.4-1.41.41.4-1.41.41.5
Time >=10cm from walls, locomotor time 11.01.01.0-1.0-1.01.0-1.01.0-1.0-1.0-1.0-1.01.01.0-1.0-1.0-1.0-1.01.01.0-1.01.01.0
Bouts of movement, locomotor time 10.91.01.0-1.0-1.01.0-1.01.0-1.0-1.0-1.0-1.01.01.0-1.0-1.0-1.0-1.01.01.0-1.01.01.0
Total resting periods, locomotor time 10.50.60.6-0.8-0.80.8-0.80.8-0.8-0.8-0.8-0.80.80.8-0.8-0.8-0.8-0.80.80.8-0.80.80.7
Rest time, locomotor task time 10.80.91.01.01.0-1.01.0-1.01.01.01.01.0-1.0-1.01.01.01.01.0-1.0-1.01.0-1.0-1.0
Distance moved, locomotor task time 11.11.31.3-1.1-1.11.1-1.11.1-1.1-1.1-1.1-1.11.11.1-1.1-1.1-1.1-1.11.11.1-1.11.11.1
Vertical activity count, locomotor time 10.10.10.1-0.2-0.20.2-0.20.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.2-0.20.20.2-0.20.20.3
Time >=10cm from walls, locomotor time 21.11.21.2-1.1-1.11.1-1.11.1-1.1-1.1-1.1-1.11.11.1-1.1-1.1-1.1-1.11.11.1-1.11.11.1
Bouts of movement, locomotor time 22.93.13.1-1.8-1.81.8-1.81.8-1.8-1.8-1.8-1.81.81.8-1.8-1.8-1.8-1.81.81.8-1.81.81.7
Total resting periods, locomotor time 24.04.24.3-2.1-2.12.1-2.12.1-2.1-2.1-2.1-2.12.12.1-2.1-2.1-2.1-2.12.12.1-2.12.12.0
Rest time, locomotor task time 20.00.00.0-0.0-0.00.0-0.00.0-0.0-0.0-0.0-0.00.00.0-0.0-0.0-0.0-0.00.00.0-0.00.00.0
Distance moved, locomotor task time 20.20.20.3-0.5-0.50.5-0.50.5-0.5-0.5-0.5-0.50.50.5-0.5-0.5-0.5-0.50.50.5-0.50.50.5
Vertical activity count, locomotor time 20.30.40.4-0.6-0.60.6-0.60.6-0.6-0.6-0.6-0.60.60.6-0.6-0.6-0.6-0.60.60.6-0.60.60.6
Light reinforcement 11.83.39.7-3.1-1.31.9-1.91.9-1.8-1.8-1.9-1.71.71.7-1.7-1.7-1.7-1.71.71.7-1.71.71.8
Light reinforcement 20.10.22.4-1.50.70.2-0.20.2-0.1-0.1-0.2-0.0-0.0-0.00.00.00.00.0-0.0-0.00.0-0.00.1
Bone: marrow area0.71.44.42.10.8-1.21.2-1.21.21.21.21.1-1.1-1.11.11.11.11.1-1.1-1.11.1-1.1-1.0
Bone: maximum diameter1.22.121.04.6-0.3-1.41.4-1.41.21.21.31.1-1.0-1.01.01.01.01.0-1.0-1.01.0-1.0-0.8
Bone: maximum force0.20.32.01.40.1-0.60.6-0.60.50.50.50.5-0.5-0.50.50.50.50.5-0.5-0.50.5-0.5-0.2
Bone: maximum moment0.20.41.51.20.3-0.70.7-0.70.60.60.60.6-0.6-0.60.60.60.60.6-0.6-0.60.6-0.6-0.4
Mean time between licks in bursts0.00.00.00.20.2-0.20.2-0.20.20.20.20.2-0.2-0.20.20.20.20.2-0.2-0.20.2-0.2-0.2
Mean num. licks in bursts0.00.00.0-0.1-0.10.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.10.10.1-0.10.10.1
Cd content in liver1.51.62.8-1.7-1.11.3-1.31.3-1.3-1.3-1.3-1.31.21.2-1.2-1.2-1.2-1.21.21.2-1.21.21.2
Co content in liver0.70.82.9-1.61.7-0.50.5-0.50.70.70.60.8-0.8-0.80.80.80.80.8-0.8-0.80.8-0.8-0.9
Cu content in liver1.11.422.8-4.81.50.7-0.70.7-0.5-0.5-0.6-0.30.20.2-0.2-0.2-0.2-0.20.20.2-0.20.20.1
Fe content in liver0.70.813.3-3.71.40.4-0.40.4-0.2-0.2-0.3-0.0-0.1-0.10.10.10.10.1-0.1-0.10.1-0.1-0.1
K content in liver2.12.122.3-4.70.51.4-1.41.4-1.1-1.1-1.3-1.00.90.9-0.9-0.9-0.9-0.90.90.9-0.90.90.8
Mg content in liver0.60.76.7-2.60.20.8-0.80.8-0.6-0.6-0.7-0.60.50.5-0.5-0.5-0.5-0.50.50.5-0.50.50.5
Mn content in liver0.10.10.20.3-0.50.2-0.20.2-0.2-0.2-0.2-0.20.30.3-0.3-0.3-0.3-0.30.30.3-0.30.30.3
Na content in liver0.50.56.5-2.50.50.6-0.60.6-0.5-0.5-0.5-0.40.30.3-0.3-0.3-0.3-0.30.30.3-0.30.30.3
Rb content in liver2.63.337.4-6.13.7-0.20.2-0.20.60.60.40.9-1.1-1.11.11.11.11.1-1.1-1.11.1-1.1-0.9
Se content in liver0.50.63.7-1.91.6-0.30.3-0.30.50.50.40.6-0.7-0.70.70.70.70.7-0.7-0.70.7-0.7-0.6
Sr content in liver5.04.613.82.2-3.71.6-1.61.6-1.9-1.9-1.8-2.02.12.1-2.1-2.1-2.1-2.12.12.1-2.12.12.1
Zn content in liver0.20.22.8-1.70.40.3-0.30.3-0.2-0.2-0.3-0.20.10.1-0.1-0.1-0.1-0.10.10.1-0.10.10.1
Bone: minimum diameter0.30.56.82.6-1.4-0.00.0-0.0-0.2-0.2-0.1-0.30.30.3-0.3-0.3-0.3-0.30.30.3-0.30.30.3
Time in familiar zone, hab. session 12.32.12.2-1.5-1.51.5-1.51.5-1.5-1.5-1.5-1.51.51.5-1.5-1.5-1.5-1.51.51.5-1.51.51.5
Time in novel zone, hab. session 12.12.12.11.41.4-1.41.4-1.41.41.41.51.4-1.4-1.41.41.41.41.4-1.4-1.41.4-1.4-1.4
Total zone transitions, hab. session 10.40.60.6-0.8-0.80.8-0.80.8-0.8-0.8-0.8-0.80.80.8-0.8-0.8-0.8-0.80.80.8-0.80.80.8
Total locomotion distance, hab. session 10.00.00.0-0.1-0.10.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.10.10.1-0.10.10.1
Locomotion velocity, hab. session 10.00.00.0-0.1-0.10.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.10.10.1-0.10.10.1
Time in familiar zone, hab. session 20.60.60.6-0.8-0.80.8-0.80.8-0.8-0.8-0.8-0.80.80.8-0.8-0.8-0.8-0.80.80.8-0.80.80.8
Time in novel zone, hab. session 21.31.31.31.11.1-1.11.1-1.11.11.11.11.1-1.1-1.11.11.11.11.1-1.1-1.11.1-1.1-1.1
Total zone transitions, hab. session 20.10.20.2-0.4-0.40.4-0.40.4-0.4-0.4-0.4-0.40.40.4-0.4-0.4-0.4-0.40.40.4-0.40.40.4
Total locomotion distance, hab. session 20.20.20.2-0.5-0.50.5-0.50.5-0.5-0.5-0.5-0.50.50.5-0.5-0.5-0.5-0.50.50.5-0.50.50.5
Locomotion velocity, hab. session 20.40.60.6-0.8-0.80.8-0.80.8-0.8-0.8-0.8-0.80.80.8-0.8-0.8-0.8-0.80.80.8-0.80.80.8
Novel to familiar place preference ratio0.00.00.0-0.2-0.20.2-0.20.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.2-0.20.20.2-0.20.20.2
Novelty place preference0.00.00.0-0.1-0.10.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.10.10.1-0.10.10.1
Time in novel zone, NPP test0.00.00.00.10.1-0.10.1-0.10.10.10.10.1-0.1-0.10.10.10.10.1-0.1-0.10.1-0.1-0.1
Total zone transitions, NPP test0.00.00.0-0.0-0.00.0-0.00.0-0.0-0.0-0.0-0.00.00.0-0.0-0.0-0.0-0.00.00.0-0.00.00.0
Total locomotion distance, NPP test0.70.90.90.90.9-0.90.9-0.90.90.90.90.9-0.9-0.90.90.90.90.9-0.9-0.90.9-0.9-0.9
Locomotion velocity, NPP test0.30.40.40.70.7-0.70.7-0.70.70.70.70.7-0.7-0.70.70.70.70.7-0.7-0.70.7-0.7-0.7
Intraocular pressure1.01.416.1-4.00.41.1-1.11.1-0.9-0.9-1.0-0.80.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.7
Delta distance traveled before/after self-admin0.00.00.0-0.2-0.20.2-0.20.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.2-0.20.20.2-0.20.20.2
Delta ambulatory time before/after self-admin0.00.00.00.10.1-0.10.1-0.10.10.10.10.1-0.1-0.10.10.10.10.1-0.1-0.10.1-0.1-0.1
Parametrial fat weight0.30.66.52.5-0.3-0.70.7-0.70.60.60.60.5-0.5-0.50.50.50.50.5-0.5-0.50.5-0.5-0.4
Pavlov. Cond. lever latency0.10.10.4-0.30.6-0.30.3-0.30.30.30.30.4-0.4-0.40.40.40.40.4-0.4-0.40.4-0.4-0.4
Pavlov. Cond. magazine entry latency0.10.10.5-0.50.7-0.30.3-0.30.30.30.30.4-0.4-0.40.40.40.40.4-0.4-0.40.4-0.4-0.4
Pavlov. Cond. change in total contacts0.60.70.9-1.0-0.70.8-0.80.8-0.8-0.8-0.8-0.80.80.8-0.8-0.8-0.8-0.80.80.8-0.80.80.8
Pavlov. Cond. index score0.00.00.10.30.0-0.10.1-0.10.10.10.10.1-0.1-0.10.10.10.10.1-0.1-0.10.1-0.1-0.1
Pavlov. Cond. latency score0.00.00.00.1-0.20.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.10.10.1-0.10.10.1
Pavlov. Cond. lever contacts0.81.01.4-0.5-1.20.9-0.90.9-1.0-1.0-1.0-1.01.01.0-1.0-1.0-1.0-1.01.01.0-1.01.01.0
Pavlov. Cond. magazine entry number0.80.92.40.5-1.50.8-0.80.8-0.9-0.9-0.9-1.01.01.0-1.0-1.0-1.0-1.01.01.0-1.01.01.0
Pavlov. Cond. intertrial magazine entries0.91.15.12.30.4-1.11.1-1.11.01.01.00.9-0.9-0.90.90.90.90.9-0.9-0.90.9-0.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.10.10.10.1-0.40.2-0.20.2-0.2-0.2-0.2-0.30.30.3-0.3-0.3-0.3-0.30.30.3-0.30.30.3
Pavlov. Cond. response bias0.10.20.6-0.60.8-0.30.3-0.30.30.30.30.4-0.4-0.40.40.40.40.4-0.4-0.40.4-0.4-0.4
Pavlov. Cond. lever latency0.40.55.82.4-0.4-0.60.6-0.60.50.50.40.4-0.4-0.40.40.40.40.4-0.4-0.40.4-0.4-0.1
Pavlov. Cond. magazine entry latency0.20.22.4-1.60.10.5-0.50.5-0.4-0.4-0.4-0.30.30.3-0.3-0.3-0.3-0.30.30.3-0.30.30.2
Pavlov. Cond. change in total contacts0.20.23.0-1.70.30.4-0.40.4-0.3-0.3-0.3-0.30.30.3-0.3-0.3-0.3-0.30.30.3-0.30.30.1
Pavlov. Cond. index score0.60.89.3-3.10.40.8-0.80.8-0.7-0.7-0.6-0.60.50.5-0.5-0.5-0.5-0.50.50.5-0.50.50.3
Pavlov. Cond. latency score0.50.66.5-2.50.20.7-0.70.7-0.6-0.6-0.6-0.50.50.5-0.5-0.5-0.5-0.50.50.5-0.50.50.4
Pavlov. Cond. lever contacts0.40.65.9-2.40.20.8-0.80.8-0.6-0.6-0.6-0.60.50.5-0.5-0.5-0.5-0.50.50.5-0.50.50.3
Pavlov. Cond. magazine entry number1.41.712.73.60.1-1.31.3-1.31.11.11.21.1-1.0-1.01.01.01.01.0-1.0-1.01.0-1.0-0.9
Pavlov. Cond. intertrial magazine entries0.00.00.2-0.50.10.1-0.10.1-0.1-0.1-0.2-0.00.00.0-0.0-0.0-0.0-0.00.00.0-0.00.00.2
Pavlov. Cond. lever-magazine prob. diff.0.60.86.7-2.60.00.9-0.90.9-0.8-0.8-0.7-0.70.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.5
Pavlov. Cond. response bias0.60.88.6-2.90.30.9-0.90.9-0.7-0.7-0.7-0.60.60.6-0.6-0.6-0.6-0.60.60.6-0.60.60.4
Time in closed arm before self-admin0.10.10.10.30.3-0.30.3-0.30.30.30.30.3-0.3-0.30.30.30.30.3-0.3-0.30.3-0.3-0.3
Time in closed arm after self-admin0.40.40.40.60.6-0.60.6-0.60.60.60.60.6-0.6-0.60.60.60.60.6-0.6-0.60.6-0.6-0.6
Time in open arm before self-admin0.80.90.91.01.0-1.01.0-1.01.01.01.01.0-1.0-1.01.01.01.01.0-1.0-1.01.0-1.0-1.0
Time in open arm after self-admin1.61.81.8-1.3-1.31.3-1.31.3-1.3-1.3-1.3-1.31.31.3-1.3-1.3-1.3-1.31.31.3-1.31.31.3
Bone: periosteal estimation0.61.31.91.41.1-1.21.2-1.21.21.21.11.1-1.1-1.11.11.11.11.1-1.1-1.11.1-1.1-1.0
Bone: periosteal perimeter0.30.58.42.9-0.8-0.50.5-0.50.30.30.40.2-0.2-0.20.20.20.20.2-0.2-0.20.2-0.2-0.0
Bone: post-yield work0.10.11.5-1.20.30.3-0.30.3-0.2-0.2-0.3-0.20.10.1-0.1-0.1-0.1-0.10.10.1-0.10.10.4
Progressive ratio test 1 active lever presses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Progressive ratio test 1 breakpoint0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Progressive ratio test 1 inactive lever presses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Progressive ratio test 2 active lever presses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Progressive ratio test 2 breakpoint0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Progressive ratio test 2 inactive lever presses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Incentive Sensitization - Responses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Incentive Sensitization - Breakpoint0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Sum of active levers in priming session hrs 5-60.60.60.6-0.8-0.80.8-0.80.8-0.8-0.8-0.8-0.80.80.8-0.8-0.8-0.8-0.80.80.8-0.80.80.8
Progressive ratio0.50.60.60.80.8-0.80.8-0.80.80.80.80.8-0.8-0.80.80.80.80.8-0.8-0.80.8-0.8-0.8
Food seeking constrained by brief footshock0.91.11.1-1.0-1.01.0-1.01.0-1.0-1.0-1.1-1.01.01.0-1.0-1.0-1.0-1.01.01.0-1.01.01.0
Seeking ratio, punishment vs. effort1.92.32.3-1.5-1.51.5-1.51.5-1.5-1.5-1.5-1.51.51.5-1.5-1.5-1.5-1.51.51.5-1.51.51.5
Retroperitoneal fat weight1.96.248.97.00.1-2.52.5-2.52.22.22.32.0-1.9-1.91.91.91.91.9-1.9-1.91.9-1.9-1.6
Reaction time number correct0.40.61.7-1.3-0.50.8-0.80.8-0.8-0.8-0.7-0.80.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.6
Reaction time mean minus median0.10.20.5-0.10.7-0.30.3-0.30.40.40.60.4-0.4-0.40.40.40.40.4-0.4-0.40.4-0.4-0.7
Reaction time mean minus median AUC0.10.10.1-0.3-0.30.4-0.40.4-0.4-0.4-0.3-0.40.40.4-0.4-0.4-0.4-0.40.40.4-0.40.40.2
Reaction time num false alarms0.30.41.91.3-1.40.3-0.30.3-0.4-0.4-0.4-0.50.50.5-0.5-0.5-0.5-0.50.50.5-0.50.50.5
Reaction time num false alarms AUC0.30.41.61.0-1.30.4-0.40.4-0.5-0.5-0.4-0.50.60.6-0.6-0.6-0.6-0.60.60.6-0.60.60.6
Reaction time trials correct on left0.40.61.7-1.3-0.50.8-0.80.8-0.8-0.8-0.7-0.80.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.6
Reaction time trials on left0.40.61.6-1.2-0.50.8-0.80.8-0.8-0.8-0.7-0.70.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.6
Reaction time mean0.10.10.7-0.80.7-0.10.1-0.10.20.20.20.2-0.2-0.20.20.20.20.2-0.2-0.20.2-0.2-0.2
Reaction time mean AUC0.10.11.3-1.10.8-0.10.1-0.10.10.10.10.2-0.2-0.20.20.20.20.2-0.2-0.20.2-0.2-0.2
Median of all reaction times0.00.11.0-1.00.50.1-0.10.1-0.0-0.0-0.10.0-0.1-0.10.10.10.10.1-0.1-0.10.1-0.10.0
Reaction time omissions0.00.00.10.10.2-0.10.1-0.10.10.10.20.1-0.1-0.10.10.10.10.1-0.1-0.10.1-0.1-0.3
Reaction time false alarm rate0.20.31.41.1-1.20.3-0.30.3-0.4-0.4-0.4-0.40.50.5-0.5-0.5-0.5-0.50.50.5-0.50.50.5
Reaction time premature initiation rate1.82.43.6-0.3-1.91.4-1.41.4-1.5-1.5-1.5-1.61.61.6-1.6-1.6-1.6-1.61.61.6-1.61.61.7
Reaction time premature initiations1.82.63.4-0.7-1.91.5-1.51.5-1.6-1.6-1.5-1.61.71.7-1.7-1.7-1.7-1.71.71.7-1.71.71.7
Std. dev. reaction times0.10.20.5-0.20.7-0.30.3-0.30.40.40.40.4-0.4-0.40.40.40.40.4-0.4-0.40.4-0.4-0.5
Reaction time trials completed0.40.61.6-1.2-0.50.8-0.80.8-0.8-0.8-0.7-0.70.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.6
Reaction time trials AUC0.40.61.5-1.2-0.60.8-0.80.8-0.8-0.8-0.7-0.80.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.6
Run reversals in cocaine runway, females0.00.00.4-0.0-0.00.0-0.00.0-0.0-0.00.0-0.00.00.0-0.0-0.0-0.0-0.00.00.0-0.00.0-0.6
Run reversals in cocaine runway, males0.00.00.00.10.1-0.10.1-0.10.10.10.10.1-0.1-0.10.10.10.10.1-0.1-0.10.1-0.1-0.1
Latency to leave start box in cocaine runway0.40.50.5-0.7-0.70.7-0.70.7-0.7-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.3
Latency to leave start box in cocaine runway, F0.91.02.11.01.0-1.01.0-1.01.01.01.01.0-1.0-1.01.01.01.01.0-1.0-1.01.0-1.0-1.4
Latency to leave start box in cocaine runway, M4.13.94.0-2.0-2.02.0-2.02.0-2.0-2.0-2.0-2.02.02.0-2.0-2.0-2.0-2.02.02.0-2.02.02.0
Std. dev. time between licks in bursts1.92.32.31.51.5-1.51.5-1.51.51.51.51.5-1.5-1.51.51.51.51.5-1.5-1.51.5-1.5-1.5
Total sessions with >9 infusions0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Short access day 1 total inactive lever presses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Short access day 10 total inactive lever presses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Short access day 1 total infusions0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Short access day 10 total infusions0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Short access total infusions0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Short access day 1 locomotion0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Short access day 10 total locomotion0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Short access total locomotion0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
One hour access (0.3 mA shock)0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Compulsive drug intake0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
One hour access (shock baseline)0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Social response proportion0.00.00.20.4-0.40.0-0.00.0-0.1-0.1-0.0-0.10.10.1-0.1-0.1-0.1-0.10.10.1-0.10.10.0
Social responses0.20.21.31.2-0.1-0.50.5-0.50.40.40.50.4-0.4-0.40.40.40.40.4-0.4-0.40.4-0.4-0.5
Social time0.10.10.10.20.2-0.30.3-0.30.30.30.30.3-0.3-0.30.30.30.30.3-0.3-0.30.3-0.3-0.3
Soleus weight0.20.62.21.4-1.50.4-0.40.4-0.6-0.6-0.5-0.60.70.7-0.7-0.7-0.7-0.70.70.7-0.70.70.7
Bone: stiffness0.10.21.01.00.2-0.50.5-0.50.50.50.40.4-0.4-0.40.40.40.40.4-0.4-0.40.4-0.4-0.4
Tibialis anterior weight0.31.016.74.1-1.5-0.50.5-0.50.20.20.40.10.00.0-0.0-0.0-0.0-0.00.00.0-0.00.0-0.1
Time to tail flick, vehicle, before self-admin0.10.10.10.20.2-0.20.2-0.20.20.20.20.2-0.2-0.20.20.20.20.2-0.2-0.20.2-0.2-0.2
Time to tail flick, vehicle, after self-admin0.90.90.9-1.0-1.01.0-1.01.0-1.0-1.0-1.0-1.01.01.0-1.0-1.0-1.0-1.01.01.0-1.01.01.0
Time to tail flick, test, before self-admin0.10.10.10.20.2-0.20.2-0.20.20.20.20.2-0.2-0.20.20.20.20.2-0.2-0.20.2-0.2-0.2
Time to tail flick, test, after self-admin0.40.40.4-0.6-0.60.6-0.60.6-0.6-0.6-0.6-0.60.60.6-0.6-0.6-0.6-0.60.60.6-0.60.60.6
Delta time to tail flick, vehicle, before/after SA0.20.20.2-0.5-0.50.5-0.50.5-0.5-0.5-0.5-0.50.50.5-0.5-0.5-0.5-0.50.50.5-0.50.50.5
Delta time to tail flick, test, before/after SA0.10.10.1-0.3-0.30.3-0.30.3-0.3-0.3-0.3-0.30.30.3-0.3-0.3-0.3-0.30.30.3-0.30.30.3
Tibia length0.51.47.32.70.4-1.21.2-1.21.11.11.21.1-1.0-1.01.01.01.01.0-1.0-1.01.0-1.0-0.9
Ambulatory time before self-admin0.30.40.4-0.6-0.60.6-0.60.6-0.6-0.6-0.6-0.60.60.6-0.6-0.6-0.6-0.60.60.6-0.60.60.6
Ambulatory time after self-admin0.70.70.7-0.9-0.90.9-0.90.9-0.9-0.9-0.9-0.90.90.9-0.9-0.9-0.9-0.90.90.9-0.90.90.9
Bone: tissue strength0.50.51.21.10.5-0.70.7-0.70.70.70.70.7-0.7-0.70.70.70.70.7-0.7-0.70.7-0.7-0.7
Total heroin consumption0.10.10.1-0.3-0.30.3-0.30.3-0.3-0.3-0.3-0.30.30.3-0.3-0.3-0.3-0.30.30.3-0.30.30.3
Bone: trabecular number0.40.61.9-1.01.4-0.60.6-0.60.70.70.50.7-0.8-0.80.80.80.80.8-0.8-0.80.8-0.8-0.5
Bone: trabecular spacing0.81.15.82.40.3-1.01.0-1.00.90.91.10.9-0.9-0.90.90.90.90.9-0.9-0.90.9-0.9-1.1
Bone: trabecular thickness0.70.82.11.40.7-0.90.9-0.90.90.90.80.9-0.9-0.90.90.90.90.9-0.9-0.90.9-0.9-0.6
Bone: trabecular tissue density0.30.46.12.5-1.0-0.20.2-0.20.10.10.2-0.00.10.1-0.1-0.1-0.1-0.10.10.1-0.10.10.1
Water consumed over 24 hours3.44.14.12.02.0-2.02.0-2.02.02.02.02.0-2.0-2.02.02.02.02.0-2.0-2.02.0-2.0-1.9
Number of responses in last shaping day0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0