Hub : Genes

Nrm

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_039098800.1 0.02 0.02 8.7e-03 0.01 0.01 0 0 3.6e-02 3.0e-02 2.1e-01 1.3e-01
2 Adipose gene expression Nrm 0.03 0.02 2.4e-03 0.02 0.01 0.01 0.02 5.5e-03 2.0e-02 1.6e-02 6.6e-03
3 Adipose isoform ratio NM_212508.2 0.05 0.04 4.4e-05 0.03 0.03 0.02 0.03 1.5e-04 3.2e-04 3.4e-03 2.5e-04
4 Adipose alternative TSS NM_212508.2 0.1 0.08 6.0e-09 0.06 0.06 0.05 0.06 2.2e-07 1.5e-07 4.3e-06 9.3e-08
5 Adipose alternative TSS XM_039098800.1 0.1 0.07 6.6e-09 0.07 0.06 0.05 0.06 1.5e-08 1.4e-07 3.0e-06 9.2e-08
6 Adipose alternative TSS NM_212508.2 0.04 0.03 1.2e-04 0.02 0.02 0.02 0.02 1.1e-03 3.2e-03 2.9e-03 2.4e-03
7 Adipose alternative TSS XM_008772732.3 0.04 0.03 1.1e-04 0.03 0.02 0.02 0.02 6.9e-04 2.5e-03 2.3e-03 2.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density1.83.14.6-1.91.6-1.71.21.4-2.12.1
Area under the delay curve2.22.43.21.3-1.71.2-1.4-1.51.8-1.8
BMI with tail1.65.26.72.2-2.52.6-2.5-2.21.9-1.9
BMI without tail3.16.39.42.9-3.03.1-2.2-1.82.2-2.2
Body weight6.125.433.15.7-5.75.8-4.6-4.24.5-4.5
Weight adjusted by age3.03.45.32.3-1.62.0-1.6-1.31.9-1.9
Bone surface0.10.20.40.6-0.60.50.20.6-0.10.1
Bone volume0.00.10.10.1-0.30.3-0.10.3-0.40.4
Breakpoint value in progressive ratio session0.91.01.3-1.10.6-1.11.11.1-0.90.9
Number of licking bursts0.50.62.4-0.00.5-0.41.21.5-0.30.3
Context. condit. distance diff. score5.87.011.0-1.82.5-2.63.33.1-2.42.4
Locomotion velocity, session 10.20.20.4-0.20.3-0.30.60.6-0.30.3
Locomotion distance, session 10.40.51.0-1.00.8-0.70.1-0.0-0.80.8
Locomotion velocity, session 20.00.00.00.2-0.10.10.20.1-0.10.1
Locomotion distance, session 20.50.61.1-0.80.7-0.70.60.5-1.11.1
Locomotion velocity, session 30.10.10.3-0.2-0.10.1-0.5-0.60.2-0.2
Locomotion distance, session 31.92.02.8-1.51.3-1.51.21.1-1.71.7
Stereotopy head waving bouts, day 31.51.83.41.8-1.61.7-0.6-0.31.3-1.3
Stereotopy head waving duration, day 31.31.52.41.5-1.31.4-0.6-0.21.4-1.4
Locomotion velocity, session 75.45.96.8-2.22.4-2.42.42.5-2.62.6
Locomotion distance, session 74.86.17.7-2.52.4-2.52.12.1-2.82.8
Stereotopy head waving bouts, day 72.42.73.01.6-1.71.7-1.6-1.71.6-1.6
Stereotopy head waving duration, day 72.93.64.12.0-2.02.0-1.8-1.81.8-1.8
Locomotion velocity, session 80.60.72.30.9-0.20.11.41.5-0.10.1
Locomotion distance, session 83.75.47.5-1.62.1-2.12.72.5-2.52.5
Degree of sensitization distance0.40.41.0-0.20.5-0.50.91.0-0.30.3
Degree of sensitization stereotypy1.51.62.51.2-1.31.3-1.4-1.61.1-1.1
Conditioned locomotion0.50.51.21.1-1.01.0-0.20.20.4-0.4
Cocaine response after cond. corrected0.40.50.7-0.80.8-0.80.60.5-0.60.6
Cocaine response after cond. not corrected0.20.20.40.6-0.40.40.10.00.5-0.5
Cocaine response before conditioning4.85.98.83.0-2.62.7-1.6-1.62.6-2.6
Saline control response1.21.63.60.6-1.01.1-1.8-1.91.0-1.0
Bone: connectivity density3.14.95.6-2.22.1-2.22.12.2-2.42.4
Bone: cortical apparent density0.50.61.7-0.0-0.40.5-1.3-1.30.6-0.6
Bone: cortical area1.62.44.41.9-2.12.0-1.4-0.81.0-1.0
Bone: cortical porosity0.60.71.00.5-0.70.7-1.0-1.00.8-0.8
Bone: cortical porosity0.60.71.01.0-0.91.0-0.6-0.40.8-0.8
Bone: cortical thickness2.43.97.51.4-2.22.2-2.7-2.31.2-1.2
Bone: cortical thickness0.60.72.0-0.0-0.60.6-1.4-1.30.4-0.4
Bone: cortical tissue density0.40.51.4-0.0-0.40.4-1.2-1.10.6-0.6
Condit. Reinf. active minus inactive responses1.21.31.8-0.91.0-1.01.21.3-1.31.3
Condit. Reinf. active-inactive response ratio0.00.00.0-0.10.00.0-0.10.1-0.00.0
Condit. Reinf. active responses1.92.32.8-1.31.5-1.51.41.5-1.71.7
Condit. Reinf. inactive responses2.63.14.3-1.91.8-1.91.31.1-2.12.1
Incentive salience index mean2.42.95.1-0.91.4-1.32.12.3-1.91.9
Condit. Reinf. lever presses3.64.87.4-1.21.9-1.72.72.7-2.32.3
Condit. Reinf. active minus inactive responses1.11.42.11.5-1.21.4-0.8-0.51.3-1.3
Condit. Reinf. active-inactive response ratio2.52.64.22.0-1.71.9-1.0-0.61.8-1.8
Condit. Reinf. active responses0.00.00.10.10.1-0.00.20.40.1-0.1
Condit. Reinf. inactive responses1.41.72.5-1.61.5-1.61.10.9-1.31.3
Condit. Reinf. lever presses0.50.60.9-0.71.0-0.80.80.9-0.70.7
Condit. Reinf. lever reinforcers received0.10.10.4-0.10.3-0.20.40.6-0.00.0
Conditioned reinforcement - actives0.40.40.60.6-0.70.7-0.6-0.40.7-0.7
Conditioned reinforcement - inactives1.01.11.70.8-1.31.1-1.2-1.10.9-0.9
Conditioned locomotion0.10.10.30.2-0.50.20.10.30.4-0.4
Patch foraging indifference point 0 sec0.30.51.6-0.0-0.40.3-1.2-1.30.4-0.4
Patch foraging indifference point AUC2.12.43.61.8-1.81.9-1.3-1.11.5-1.5
Delay disc. indifference point, 0s delay0.40.40.90.9-1.00.7-0.1-0.00.6-0.6
Delay disc. indifference point, 16s delay1.31.32.80.4-0.70.5-1.5-1.71.2-1.2
Delay disc. indifference point, 2s delay2.93.24.51.8-2.01.7-1.3-1.22.1-2.1
Delay disc. indifference point, 24s delay0.70.71.00.4-0.90.4-0.9-1.00.9-0.9
Delay disc. indifference point, 4s delay2.93.05.62.0-2.41.6-1.1-1.21.8-1.8
Delay disc. indifference point, 8s delay0.40.40.60.5-0.60.3-0.5-0.60.8-0.8
Indifference point function ln k0.40.51.0-0.40.6-0.61.01.0-0.70.7
Indifference point function log k0.40.51.0-0.40.6-0.61.01.0-0.70.7
Patch foraging total patch changes 0 sec0.40.72.10.1-0.60.5-1.4-1.40.4-0.4
Patch foraging total patch changes 12 sec0.81.02.20.3-0.70.7-1.5-1.50.9-0.9
Patch foraging total patch changes 18 sec0.40.51.6-0.80.10.0-1.2-1.3-0.00.0
Patch foraging total patch changes 24 sec0.70.82.5-1.60.9-1.0-0.5-0.5-0.60.6
Patch foraging total patch changes 6 sec0.50.72.1-0.2-0.40.4-1.5-1.40.5-0.5
Patch foraging time to switch 0 sec0.30.41.2-1.10.8-0.8-0.3-0.5-0.10.1
Patch foraging water rate 0 sec0.30.50.90.8-0.90.9-0.7-0.60.5-0.5
Patch foraging water rate 12 sec0.10.20.4-0.60.2-0.4-0.2-0.2-0.60.6
Patch foraging water rate 18 sec0.20.20.40.6-0.60.6-0.10.1-0.40.4
Patch foraging water rate 24 sec1.52.12.91.4-1.71.7-1.5-1.51.0-1.0
Patch foraging water rate 6 sec0.10.10.2-0.2-0.10.1-0.4-0.4-0.20.2
Seeking ratio, delayed vs. immediate footshock0.40.50.90.8-0.91.0-0.5-0.50.4-0.4
Distance traveled before self-admin0.20.20.80.30.1-0.00.70.9-0.40.4
Distance traveled after self-admin0.20.20.60.8-0.10.3-0.1-0.40.6-0.6
Extensor digitorum longus weight0.10.30.80.7-0.30.40.50.90.1-0.1
Bone: elastic displacement0.30.41.2-0.1-0.50.2-0.9-1.10.4-0.4
Bone: elastic work1.92.43.41.4-1.81.6-1.7-1.61.3-1.3
Bone: endosteal estimation2.24.710.93.3-2.42.4-0.20.22.3-2.3
Bone: endosteal perimeter0.51.12.61.5-0.50.51.41.60.5-0.5
Epididymis fat weight2.76.217.9-0.2-1.21.4-4.0-4.21.7-1.7
Delta time in closed arm before/after self-admin0.30.30.60.5-0.50.4-0.4-0.20.8-0.8
Delta time in open arm before/after self-admin0.00.00.1-0.00.0-0.0-0.1-0.2-0.30.3
Diff in mean of infusions in LGA sessions4.14.56.0-2.31.6-2.51.92.1-2.12.1
Delay discount exponential model param2.32.43.4-1.21.7-1.11.41.5-1.81.8
Extinction: sum of active levers before priming0.50.50.8-0.90.9-0.90.70.7-0.50.5
Active lever presses in extinction session 60.30.30.6-0.50.8-0.5-0.4-0.70.2-0.2
Bone: final force5.69.011.22.8-3.33.3-3.3-3.02.5-2.5
Bone: final moment4.98.010.12.7-3.23.1-3.1-2.82.3-2.3
Food consumed during 24 hour testing period0.60.71.61.3-1.21.1-0.2-0.20.5-0.5
Glucose1.21.96.30.50.6-0.52.32.5-0.40.4
Heart weight0.30.51.10.6-0.40.5-0.4-0.51.1-1.1
Delay discount hyperbolic model param2.52.63.7-1.41.8-1.31.41.5-1.91.9
Intermittent access intake day 1-15 change0.70.72.80.7-1.70.8-0.6-0.60.1-0.1
Intermittent access intake escalation0.40.41.70.7-1.30.5-0.1-0.1-0.10.1
Intermittent access intake escalation 20.50.50.90.8-0.6-0.10.91.0-0.50.5
Intermitt. access day 1 inactive lever presses0.30.30.70.8-0.40.5-0.1-0.00.8-0.8
Intermitt. access day 15 inactive lever presses2.32.53.41.7-1.21.8-1.7-1.51.6-1.6
Intermitt. access escalation Index2.52.33.2-1.71.7-1.81.41.2-1.31.3
Intermittent access day 1 total infusions0.40.40.8-0.90.5-0.70.60.7-0.60.6
Intermittent access day 15 total infusions0.20.20.4-0.4-0.7-0.20.20.3-0.50.5
Intermittent access terminal intake (last 3 days)0.10.10.60.1-0.80.3-0.2-0.10.1-0.1
Intermittent access total infusions0.00.00.1-0.3-0.3-0.00.00.2-0.20.2
Intermittent access day 1 locomotion0.30.30.7-0.3-0.3-0.50.70.8-0.50.5
Intermittent access day 15 total locomotion0.70.72.41.2-1.51.0-0.10.10.2-0.2
Intermittent access total locomotion0.50.52.31.0-1.50.7-0.00.20.0-0.0
Intermittent access standard deviation2.42.64.21.3-2.01.6-1.7-1.71.3-1.3
Left kidney weight4.211.713.83.5-3.73.7-3.3-3.33.2-3.2
Right kidney weight3.18.712.83.6-3.53.6-2.4-2.22.5-2.5
Cocaine induced anxiety3.13.64.9-1.11.8-1.72.22.2-2.02.0
Post-drug Anxiety1.01.12.5-0.61.6-0.91.21.2-0.80.8
Baseline Anxiety0.30.30.7-0.10.10.2-0.7-0.70.8-0.8
Tail length4.012.224.04.9-4.34.3-1.8-1.33.1-3.1
Length with tail4.215.424.65.0-4.64.5-2.8-2.73.7-3.7
Length without tail3.47.59.63.1-3.02.9-2.3-2.32.8-2.8
Times rat made contact with spout1.51.73.2-1.81.3-1.40.40.2-1.61.6
Lifetime Intake0.00.00.1-0.1-0.20.00.10.3-0.10.1
Liver weight, left0.40.61.81.3-0.91.0-0.1-0.30.5-0.5
Liver weight, right3.45.610.23.2-2.72.6-1.2-1.22.5-2.5
Locomotor activity1.01.64.12.0-1.51.4-0.1-0.01.1-1.1
Locomotor testing distance0.20.30.60.8-0.50.50.00.10.5-0.5
Locomotor testing rearing0.50.71.51.2-1.00.9-0.3-0.20.9-0.9
Locomotion in novel chamber0.70.91.70.9-1.30.8-0.8-0.90.8-0.8
Locomotion in novel chamber post-restriction0.70.81.10.7-1.00.8-1.0-1.10.9-0.9
Fecal boli incidents, locomotor time 10.70.81.2-0.91.1-0.80.70.7-0.90.9
Change in fecal boli incidents, locomotor task1.21.12.40.9-0.90.7-0.7-0.61.6-1.6
Time >=10cm from walls, locomotor time 10.60.61.31.2-0.31.0-0.3-0.11.0-1.0
Bouts of movement, locomotor time 11.71.92.7-0.81.1-1.31.61.5-1.51.5
Total resting periods, locomotor time 11.01.12.0-0.40.6-1.01.41.3-1.21.2
Rest time, locomotor task time 10.20.20.40.5-0.10.30.60.7-0.20.2
Distance moved, locomotor task time 10.70.81.30.5-0.50.8-1.1-1.10.9-0.9
Vertical activity count, locomotor time 10.50.51.00.2-0.40.8-1.0-1.00.5-0.5
Time >=10cm from walls, locomotor time 20.20.20.30.5-0.30.6-0.10.10.6-0.6
Bouts of movement, locomotor time 20.80.82.61.2-1.61.0-0.2-0.20.6-0.6
Total resting periods, locomotor time 20.50.51.41.1-1.20.70.20.30.5-0.5
Rest time, locomotor task time 20.60.61.80.60.2-0.01.41.4-0.50.5
Distance moved, locomotor task time 20.70.81.90.1-0.60.7-1.4-1.40.8-0.8
Vertical activity count, locomotor time 20.10.10.4-0.3-0.20.1-0.6-0.60.2-0.2
Light reinforcement 10.30.51.2-0.1-0.30.0-0.9-1.10.8-0.8
Light reinforcement 20.50.71.21.1-1.10.9-0.6-0.60.7-0.7
Bone: marrow area2.24.710.73.3-2.42.4-0.20.22.3-2.3
Bone: maximum diameter0.51.02.81.7-1.11.10.51.00.4-0.4
Bone: maximum force4.47.610.32.8-3.23.1-2.9-2.62.2-2.2
Bone: maximum moment4.06.99.72.8-3.13.0-2.7-2.42.1-2.1
Mean time between licks in bursts0.50.72.10.70.1-0.01.41.5-0.30.3
Mean num. licks in bursts0.50.61.9-0.80.1-0.3-0.9-1.4-0.50.5
Cd content in liver0.30.30.70.2-0.60.6-0.8-0.70.1-0.1
Co content in liver1.61.92.90.7-1.01.1-1.7-1.61.6-1.6
Cu content in liver2.73.26.8-2.62.2-2.10.80.5-1.61.6
Fe content in liver0.91.12.60.2-0.70.6-1.4-1.61.0-1.0
K content in liver0.20.20.4-0.40.6-0.40.50.6-0.30.3
Mg content in liver2.82.96.1-0.91.5-1.52.32.5-1.31.3
Mn content in liver1.41.65.00.10.8-0.82.22.2-0.40.4
Na content in liver0.10.10.10.0-0.20.2-0.3-0.3-0.30.3
Rb content in liver1.01.21.5-1.21.2-1.21.11.0-1.01.0
Se content in liver1.51.96.20.10.5-0.82.12.5-0.90.9
Sr content in liver0.80.71.21.1-0.80.8-0.4-0.41.0-1.0
Zn content in liver0.10.10.20.10.1-0.00.20.40.5-0.5
Bone: minimum diameter0.71.43.61.9-1.31.20.71.30.6-0.6
Time in familiar zone, hab. session 13.02.85.5-2.41.9-2.00.70.4-1.71.7
Time in novel zone, hab. session 11.81.83.11.8-1.31.4-0.4-0.31.6-1.6
Total zone transitions, hab. session 10.60.91.2-1.01.1-1.00.70.6-1.01.0
Total locomotion distance, hab. session 10.50.81.0-1.00.9-0.90.60.4-1.01.0
Locomotion velocity, hab. session 10.20.30.6-0.70.6-0.60.20.1-0.70.7
Time in familiar zone, hab. session 20.30.30.6-0.70.7-0.6-0.1-0.4-0.30.3
Time in novel zone, hab. session 20.30.30.50.6-0.70.6-0.30.00.6-0.6
Total zone transitions, hab. session 20.10.10.5-0.20.1-0.1-0.5-0.70.1-0.1
Total locomotion distance, hab. session 20.91.22.0-1.41.2-1.30.70.4-1.21.2
Locomotion velocity, hab. session 21.01.42.0-1.41.3-1.30.80.5-1.31.3
Novel to familiar place preference ratio0.00.00.0-0.10.00.0-0.2-0.0-0.20.2
Novelty place preference0.00.00.10.2-0.30.3-0.3-0.10.1-0.1
Time in novel zone, NPP test0.10.10.20.3-0.40.5-0.4-0.20.2-0.2
Total zone transitions, NPP test1.21.72.1-1.41.3-1.41.10.9-1.51.5
Total locomotion distance, NPP test1.21.72.4-1.61.3-1.40.80.7-1.51.5
Locomotion velocity, NPP test2.12.94.0-2.01.7-1.81.21.0-2.02.0
Intraocular pressure1.42.03.5-1.31.2-1.31.11.0-1.91.9
Delta distance traveled before/after self-admin1.41.52.31.1-0.90.9-1.2-1.51.3-1.3
Delta ambulatory time before/after self-admin0.80.81.20.8-0.70.7-0.7-1.11.1-1.1
Parametrial fat weight2.34.55.71.9-2.22.3-2.4-2.31.9-1.9
Pavlov. Cond. lever latency1.52.04.10.0-0.80.8-2.0-2.01.5-1.5
Pavlov. Cond. magazine entry latency1.31.73.6-0.20.9-1.01.91.8-1.31.3
Pavlov. Cond. change in total contacts0.40.41.51.2-0.80.70.30.4-0.00.0
Pavlov. Cond. index score2.02.55.2-0.10.9-1.02.32.3-1.61.6
Pavlov. Cond. latency score1.51.94.20.20.6-0.72.02.1-1.41.4
Pavlov. Cond. lever contacts1.01.12.60.40.3-0.31.51.6-1.11.1
Pavlov. Cond. magazine entry number1.92.34.20.8-1.31.4-2.0-1.91.4-1.4
Pavlov. Cond. intertrial magazine entries0.40.51.6-1.30.7-0.80.00.1-0.60.6
Pavlov. Cond. lever-magazine prob. diff.2.22.75.3-0.31.0-1.12.32.3-1.71.7
Pavlov. Cond. response bias2.12.65.1-0.41.1-1.22.32.2-1.61.6
Pavlov. Cond. lever latency0.30.40.60.7-0.80.6-0.4-0.40.6-0.6
Pavlov. Cond. magazine entry latency0.50.61.01.0-0.81.0-0.7-0.80.6-0.6
Pavlov. Cond. change in total contacts0.20.20.50.2-0.30.6-0.7-0.70.1-0.1
Pavlov. Cond. index score0.00.00.10.10.10.2-0.2-0.3-0.10.1
Pavlov. Cond. latency score0.10.10.20.2-0.10.4-0.4-0.50.1-0.1
Pavlov. Cond. lever contacts0.20.20.4-0.70.6-0.3-0.2-0.3-0.50.5
Pavlov. Cond. magazine entry number0.40.40.9-0.60.6-0.80.80.9-0.20.2
Pavlov. Cond. intertrial magazine entries1.41.84.0-0.71.0-1.32.02.0-0.90.9
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.10.10.2-0.2-0.3-0.10.1
Pavlov. Cond. response bias0.10.20.4-0.40.5-0.2-0.0-0.2-0.60.6
Time in closed arm before self-admin0.00.00.1-0.10.30.1-0.00.0-0.10.1
Time in closed arm after self-admin0.70.71.10.6-0.60.8-1.1-0.80.9-0.9
Time in open arm before self-admin0.30.40.8-0.10.3-0.60.90.8-0.60.6
Time in open arm after self-admin0.90.91.4-0.60.9-1.01.20.9-1.01.0
Bone: periosteal estimation2.44.99.93.1-2.72.7-1.0-0.42.1-2.1
Bone: periosteal perimeter1.01.64.12.0-1.61.6-0.20.31.0-1.0
Bone: post-yield work0.30.41.20.5-0.10.11.01.1-0.30.3
Progressive ratio test 1 active lever presses0.10.10.2-0.5-0.2-0.40.30.4-0.10.1
Progressive ratio test 1 breakpoint0.10.10.2-0.5-0.1-0.40.30.4-0.00.0
Progressive ratio test 1 inactive lever presses0.10.10.2-0.50.1-0.1-0.10.0-0.30.3
Progressive ratio test 2 active lever presses0.70.71.1-1.10.2-0.90.70.8-1.01.0
Progressive ratio test 2 breakpoint1.21.42.2-1.40.5-1.10.91.0-1.51.5
Progressive ratio test 2 inactive lever presses0.20.20.50.7-0.60.7-0.3-0.10.3-0.3
Incentive Sensitization - Responses0.70.71.2-1.00.3-0.80.70.7-1.11.1
Incentive Sensitization - Breakpoint0.90.91.6-1.00.4-0.90.80.8-1.31.3
Sum of active levers in priming session hrs 5-60.30.30.7-0.70.5-0.80.60.5-0.30.3
Progressive ratio5.46.39.02.2-3.02.7-2.5-2.42.3-2.3
Food seeking constrained by brief footshock0.00.00.0-0.10.20.0-0.0-0.0-0.00.0
Seeking ratio, punishment vs. effort4.45.48.2-2.12.9-2.42.32.3-2.12.1
Retroperitoneal fat weight0.41.41.91.0-1.11.0-1.3-1.41.2-1.2
Reaction time number correct0.20.31.1-0.4-0.10.1-1.0-1.10.2-0.2
Reaction time mean minus median0.70.92.60.8-0.1-0.21.61.4-0.70.7
Reaction time mean minus median AUC0.60.72.20.40.1-0.41.51.3-0.70.7
Reaction time num false alarms0.40.50.90.9-0.91.0-0.5-0.30.6-0.6
Reaction time num false alarms AUC0.71.01.41.2-1.11.2-0.7-0.51.1-1.1
Reaction time trials correct on left0.20.31.1-0.4-0.10.1-1.0-1.10.2-0.2
Reaction time trials on left0.20.31.1-0.3-0.10.1-1.0-1.10.3-0.3
Reaction time mean1.11.64.10.30.4-0.72.02.0-1.11.1
Reaction time mean AUC1.11.53.90.30.3-0.62.01.9-1.01.0
Median of all reaction times0.91.23.10.10.4-0.61.71.8-0.90.9
Reaction time omissions0.71.02.60.40.2-0.31.61.6-0.80.8
Reaction time false alarm rate0.40.61.41.2-0.80.90.00.20.8-0.8
Reaction time premature initiation rate1.52.02.31.3-1.41.5-1.5-1.31.5-1.5
Reaction time premature initiations2.02.84.11.2-1.51.6-2.0-1.91.7-1.7
Std. dev. reaction times0.60.92.61.0-0.2-0.11.61.5-0.40.4
Reaction time trials completed0.20.31.1-0.3-0.10.1-1.0-1.10.3-0.3
Reaction time trials AUC0.20.31.0-0.4-0.10.1-0.9-1.00.2-0.2
Run reversals in cocaine runway, females0.10.10.3-0.30.50.0-0.5-0.5-0.30.3
Run reversals in cocaine runway, males0.70.72.01.4-0.91.2-0.00.20.5-0.5
Latency to leave start box in cocaine runway0.20.20.60.3-0.10.4-0.4-0.30.8-0.8
Latency to leave start box in cocaine runway, F0.20.20.5-0.40.7-0.40.50.6-0.10.1
Latency to leave start box in cocaine runway, M1.71.62.41.0-1.11.2-1.5-1.51.3-1.3
Std. dev. time between licks in bursts0.50.61.71.0-0.10.31.11.30.4-0.4
Total sessions with >9 infusions0.10.10.20.2-0.40.3-0.00.30.2-0.2
Short access day 1 total inactive lever presses0.30.40.80.9-0.60.40.60.90.2-0.2
Short access day 10 total inactive lever presses0.00.00.10.30.0-0.00.30.30.1-0.1
Short access day 1 total infusions0.20.20.6-0.50.4-0.50.60.8-0.10.1
Short access day 10 total infusions0.00.10.10.2-0.00.3-0.10.10.3-0.3
Short access total infusions0.10.10.20.2-0.20.4-0.10.20.4-0.4
Short access day 1 locomotion3.74.04.9-1.81.9-2.12.12.2-1.81.8
Short access day 10 total locomotion0.20.30.60.8-0.00.10.50.70.5-0.5
Short access total locomotion0.30.31.0-0.10.5-0.40.71.0-0.10.1
One hour access (0.3 mA shock)0.70.81.0-0.90.6-0.90.91.0-0.90.9
Compulsive drug intake2.72.74.0-1.72.0-1.81.71.7-1.31.3
One hour access (shock baseline)0.30.40.80.9-0.90.9-0.5-0.40.3-0.3
Social response proportion0.30.30.90.5-0.30.10.0-0.10.9-0.9
Social responses0.50.61.60.6-0.50.4-0.5-0.61.3-1.3
Social time0.40.61.21.1-0.40.40.80.80.7-0.7
Soleus weight0.61.84.12.0-1.11.01.21.80.8-0.8
Bone: stiffness0.91.42.21.1-1.31.4-1.5-1.20.8-0.8
Tibialis anterior weight0.00.10.2-0.50.20.1-0.4-0.1-0.40.4
Time to tail flick, vehicle, before self-admin0.10.10.2-0.1-0.0-0.10.40.5-0.40.4
Time to tail flick, vehicle, after self-admin1.01.02.6-0.30.7-0.71.51.6-0.80.8
Time to tail flick, test, before self-admin0.10.10.4-0.0-0.10.0-0.4-0.60.2-0.2
Time to tail flick, test, after self-admin1.92.03.5-0.70.3-1.01.61.6-1.91.9
Delta time to tail flick, vehicle, before/after SA0.70.70.9-0.80.9-0.80.90.9-0.90.9
Delta time to tail flick, test, before/after SA1.81.73.0-1.00.6-1.01.31.3-1.71.7
Tibia length2.56.912.33.5-3.02.9-1.4-1.22.8-2.8
Ambulatory time before self-admin0.10.10.20.20.00.10.30.4-0.20.2
Ambulatory time after self-admin0.20.20.40.70.20.3-0.1-0.30.5-0.5
Bone: tissue strength4.44.25.41.9-2.22.2-2.3-2.31.7-1.7
Total heroin consumption0.10.20.4-0.10.10.00.40.6-0.60.6
Bone: trabecular number2.13.25.1-2.01.5-1.71.21.3-2.32.3
Bone: trabecular spacing4.76.17.32.7-2.32.6-2.1-2.22.7-2.7
Bone: trabecular thickness1.61.92.9-1.51.1-1.30.91.0-1.71.7
Bone: trabecular tissue density2.02.83.11.6-1.71.7-1.7-1.71.7-1.7
Water consumed over 24 hours0.00.00.10.2-0.10.10.20.30.3-0.3
Number of responses in last shaping day0.30.30.60.7-0.70.4-0.10.20.8-0.8