Hub : Traits : Body weight : ← : →

chr5:51,543,855-54,764,625

Trait: Body weight

Best TWAS P = 7.92e-10 · Best GWAS P= 5.82e-10 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	RGD1359108	alternative polyA	XM_039109829.2	0.13	195	0.07	1.8e-08	-6.15	7.92e-10	0.73	TRUE
Adipose	RGD1359108	alternative polyA	XM_039109830.2	0.13	112	0.07	1.8e-08	6.15	7.98e-10	0.73	FALSE
Adipose	Akirin2	alternative TSS	NM_001039914.2	0.02	74	0.01	1.4e-02	5.28	1.32e-07	0.28	FALSE
Adipose	Rars2	alternative TSS	XM_039109436.2	0.04	1	0.03	2.8e-04	5.6	2.09e-08	0.09	FALSE
Adipose	Rars2	alternative TSS	NM_001106643.2	0.02	1	0.01	7.0e-03	-5.32	1.03e-07	0.03	FALSE
Adipose	Rars2	alternative TSS	XM_006237986.5	0.04	1	0.04	7.3e-05	5.6	2.09e-08	0.15	FALSE
Adipose	Cnr1	gene expression	Cnr1	0.06	1	0.03	8.2e-04	-5.31	1.07e-07	0.03	FALSE
Adipose	LOC103692331	gene expression	LOC103692331	0.02	1449	0.01	3.4e-02	5.47	4.55e-08	0.22	FALSE
Adipose	Orc3	gene expression	Orc3	0.03	1	0.02	2.2e-03	5.36	8.18e-08	0.03	FALSE
Adipose	Pm20d2	gene expression	Pm20d2	0.02	1	0.01	1.6e-02	-5.55	2.86e-08	0.03	FALSE
Adipose	RGD1359108	gene expression	RGD1359108	0.18	1	0.08	2.3e-09	6.13	8.90e-10	0.81	FALSE
Adipose	Slc35a1	gene expression	Slc35a1	0.1	8	0.06	2.3e-07	5.41	6.21e-08	0.5	FALSE
Adipose	RGD1359108	isoform ratio	XR_010066381.1	0.05	125	0.02	3.6e-03	6.07	1.29e-09	0.62	FALSE
Adipose	Pm20d2	intron excision ratio	chr5_52375967_52379875	0.02	1	0.01	1.0e-02	-5.55	2.86e-08	0.03	FALSE
Adipose	Pm20d2	intron excision ratio	chr5_52375967_52379879	0.02	1	0.01	1.2e-02	5.55	2.86e-08	0.03	FALSE
Adipose	Rars2	intron excision ratio	chr5_54006631_54007791	0.03	1	0.02	2.7e-03	-5.24	1.61e-07	0.03	FALSE
Adipose	Slc35a1	mRNA stability	Slc35a1	0.05	1	0.03	1.4e-04	-5.24	1.61e-07	0.03	FALSE
BLA	Cfap206	gene expression	Cfap206	0.76	1585	0.66	4.3e-46	-5.64	1.72e-08	0.44	FALSE
BLA	LOC103692331	gene expression	LOC103692331	0.11	1449	0.1	4.1e-06	5.46	4.64e-08	0.4	FALSE
BLA	LOC120102853	gene expression	LOC120102853	0.05	1	0.01	5.7e-02	-5.35	8.92e-08	0.04	FALSE
BLA	LOC134486925	gene expression	LOC134486925	0.65	982	0.28	2.5e-15	6.11	1.03e-09	0.78	FALSE
BLA	Rars2	gene expression	Rars2	0.09	1626	0.06	2.4e-04	5.48	4.22e-08	0.49	FALSE
BLA	Rngtt	gene expression	Rngtt	0.14	95	0.1	5.2e-06	-5.58	2.46e-08	0.66	FALSE
BLA	Rars2	mRNA stability	Rars2	0.1	1626	0.05	7.5e-04	5.23	1.66e-07	0.52	FALSE
BLA	Srsf12	mRNA stability	Srsf12	0.09	348	0.08	5.6e-05	5.82	5.84e-09	0.7	FALSE
Brain	Rars2	alternative polyA	NM_001106643.2	0.05	1	0.05	1.1e-05	-5.32	1.03e-07	0.08	FALSE
Brain	Rars2	alternative polyA	XM_006237986.5	0.11	32	0.11	1.7e-10	-5.28	1.32e-07	0.5	FALSE
Brain	Rars2	alternative polyA	NM_001106643.2	0.13	1	0.14	7.9e-13	-5.28	1.33e-07	0.16	FALSE
Brain	Rars2	alternative polyA	XM_006237986.5	0.13	1	0.14	4.5e-13	5.28	1.33e-07	0.16	FALSE
Brain	RGD1359108	alternative polyA	XM_039109829.2	0.16	1	0.12	1.4e-11	-6.08	1.22e-09	0.76	FALSE
Brain	RGD1359108	alternative polyA	XM_039109830.2	0.17	1	0.13	4.7e-12	6.08	1.22e-09	0.76	FALSE
Brain	Cfap206	gene expression	Cfap206	0.65	26	0.6	2.3e-69	-5.53	3.19e-08	0.43	FALSE
Brain	LOC103692331	gene expression	LOC103692331	0.06	1449	0.07	7.2e-07	5.51	3.51e-08	0.48	FALSE
Brain	LOC134486925	gene expression	LOC134486925	0.4	10	0.25	9.6e-23	6.02	1.69e-09	0.74	FALSE
Brain	Rngtt	gene expression	Rngtt	0.36	794	0.07	8.5e-07	5.54	3.02e-08	0.66	FALSE
Brain	Rars2	isoform ratio	XM_006237986.5	0.08	1626	0.06	1.6e-06	-5.47	4.62e-08	0.46	FALSE
Brain	RGD1359108	isoform ratio	XR_010066381.1	0.05	1	0.03	8.6e-04	6.08	1.22e-09	0.05	FALSE
Brain	Slc35a1	intron excision ratio	chr5_54022929_54026987	0.04	1	0.03	3.7e-04	5.36	8.35e-08	0.04	FALSE
Brain	LOC120102853	mRNA stability	LOC120102853	0.03	1	0.04	3.3e-04	-5.41	6.48e-08	0.04	FALSE
Brain	RGD1359108	mRNA stability	RGD1359108	0.07	1	0.05	1.5e-05	-5.98	2.30e-09	0.22	FALSE
Brain	Slc35a1	mRNA stability	Slc35a1	0.09	1	0.06	1.3e-06	-5.71	1.11e-08	0.59	FALSE
Eye	Cnr1	gene expression	Cnr1	0.98	55	0.06	4.4e-02	5.25	1.49e-07	0.16	FALSE
Eye	Gabrr2	isoform ratio	NM_017292.2	0.33	29	0.19	7.4e-04	5.35	8.62e-08	0.52	FALSE
Eye	Pm20d2	isoform ratio	XM_063287585.1	0.4	1	0.02	1.7e-01	-5.53	3.24e-08	0.06	FALSE
IC	Cfap206	gene expression	Cfap206	0.22	1585	0.14	2.0e-06	-5.43	5.70e-08	0.42	FALSE
IC	Cnr1	gene expression	Cnr1	0.08	3	0.04	1.2e-02	5.52	3.39e-08	0.34	FALSE
IC	LOC103692331	gene expression	LOC103692331	0.2	1449	0.08	3.2e-04	5.33	1.01e-07	0.43	FALSE
IC	LOC120102853	gene expression	LOC120102853	0.08	25	0.02	5.1e-02	5.49	3.93e-08	0.34	FALSE
IC	Rngtt	gene expression	Rngtt	0.26	794	0.12	7.5e-06	5.71	1.11e-08	0.63	FALSE
IC	RGD1359108	isoform ratio	NM_001007702.2	0.1	1	0.06	1.7e-03	-5.5	3.72e-08	0.04	FALSE
IL	Rars2	alternative polyA	XM_006237986.5	0.29	1626	0.12	8.9e-04	-5.54	3.11e-08	0.45	FALSE
IL	Rars2	alternative polyA	NM_001106643.2	0.29	1626	0.12	8.5e-04	5.55	2.84e-08	0.46	FALSE
IL	Rars2	alternative polyA	XM_006237986.5	0.28	1626	0.12	1.0e-03	-5.55	2.90e-08	0.46	FALSE
IL	Cfap206	gene expression	Cfap206	0.42	1	0.19	2.4e-05	5.71	1.11e-08	0.07	FALSE
IL	Rars2	isoform ratio	XM_006237986.5	0.19	1626	0.07	8.8e-03	-5.42	6.07e-08	0.38	FALSE
IL	Rngtt	mRNA stability	Rngtt	0.5	794	0.04	5.0e-02	5.67	1.40e-08	0.27	FALSE
LHb	Cfap206	gene expression	Cfap206	0.67	1	0.4	1.3e-10	5.71	1.11e-08	0.51	FALSE
Liver	Rars2	alternative polyA	XM_006237986.5	0.03	1	0.02	1.2e-03	-5.34	9.14e-08	0.03	FALSE
Liver	Rars2	alternative polyA	XM_006237986.5	0.03	1626	0.02	5.7e-03	5.28	1.27e-07	0.48	FALSE
Liver	RGD1359108	alternative polyA	XM_039109829.2	0.04	1	0.01	7.2e-03	-5.34	9.14e-08	0.03	FALSE
Liver	RGD1359108	alternative polyA	XM_039109830.2	0.04	1	0.02	3.8e-03	5.34	9.14e-08	0.03	FALSE
Liver	Orc3	gene expression	Orc3	0.03	1	0.01	1.0e-02	5.31	1.07e-07	0.03	FALSE
Liver	Slc35a1	gene expression	Slc35a1	0.12	1621	0.09	7.8e-10	5.58	2.38e-08	0.49	FALSE
Liver	Rars2	isoform ratio	NM_001106643.2	0.02	1	0.01	2.1e-02	5.31	1.07e-07	0.03	FALSE
Liver	Rars2	intron excision ratio	chr5_53980699_53982440	0.22	1	0.12	2.1e-13	5.38	7.55e-08	0.25	FALSE
Liver	Rars2	intron excision ratio	chr5_53980699_53984117	0.16	1	0.12	6.6e-13	-5.38	7.55e-08	0.25	FALSE
Liver	Rars2	intron excision ratio	chr5_54018938_54029227	0.03	1626	0	1.1e-01	5.55	2.86e-08	0.37	FALSE
NAcc	Rars2	alternative polyA	XM_006237986.5	0.06	1626	0.05	3.4e-08	-5.32	1.05e-07	0.52	FALSE
NAcc	Rars2	alternative polyA	NM_001106643.2	0.05	1626	0.04	1.7e-07	5.25	1.55e-07	0.51	FALSE
NAcc	Rars2	alternative polyA	XM_006237986.5	0.05	1626	0.05	1.1e-07	-5.21	1.92e-07	0.51	FALSE
NAcc	Cfap206	alternative TSS	NM_001079701.1	0.05	1585	0.06	5.6e-09	5.57	2.54e-08	0.42	FALSE
NAcc	Cfap206	alternative TSS	NM_001079701.1	0.05	1585	0.06	4.1e-09	5.53	3.21e-08	0.41	FALSE
NAcc	RGD1359108	alternative TSS	NM_001007702.2	0.03	1080	0.02	4.0e-04	5.68	1.36e-08	0.74	FALSE
NAcc	RGD1359108	alternative TSS	XM_039109829.2	0.04	1	0.03	7.4e-05	6.07	1.26e-09	0.64	FALSE
NAcc	RGD1359108	alternative TSS	NM_001007702.2	0.05	34	0.04	3.4e-06	-5.7	1.22e-08	0.74	FALSE
NAcc	RGD1359108	alternative TSS	XM_039109829.2	0.05	18	0.04	2.7e-06	5.71	1.13e-08	0.74	FALSE
NAcc	Cfap206	gene expression	Cfap206	0.8	132	0.55	7.2e-101	5.6	2.19e-08	0.42	FALSE
NAcc	LOC103692331	gene expression	LOC103692331	0.01	1	0.01	2.2e-03	-5.7	1.18e-08	0.04	FALSE
NAcc	LOC134486925	gene expression	LOC134486925	0.28	37	0.29	6.9e-44	5.87	4.23e-09	0.78	FALSE
NAcc	Pm20d2	gene expression	Pm20d2	0.01	1	0.02	1.6e-04	-5.38	7.33e-08	0.06	FALSE
NAcc	Cfap206	isoform ratio	XM_017593532.3	0.07	1585	0.08	1.3e-12	-5.62	1.94e-08	0.4	FALSE
NAcc	Slc35a1	intron excision ratio	chr5_54022929_54026987	0.03	1	0.03	6.8e-06	5.57	2.48e-08	0.4	FALSE
NAcc	Slc35a1	intron excision ratio	chr5_54027121_54027542	0.03	1621	0.02	2.8e-04	5.58	2.34e-08	0.5	FALSE
NAcc	Slc35a1	intron excision ratio	chr5_54027718_54029841	0.03	41	0.04	2.4e-06	-5.55	2.82e-08	0.55	FALSE
NAcc	Rars2	mRNA stability	Rars2	0.03	21	0.04	2.5e-06	5.47	4.56e-08	0.5	FALSE
NAcc	Slc35a1	mRNA stability	Slc35a1	0.03	1	0.03	9.7e-05	5.57	2.48e-08	0.5	FALSE
OFC	LOC103692331	gene expression	LOC103692331	0.14	1	0.06	1.5e-02	-5.7	1.18e-08	0.05	FALSE
PL	Rars2	alternative polyA	XM_006237986.5	0.05	1626	0.04	1.2e-05	-5.5	3.85e-08	0.49	FALSE
PL	Rars2	alternative polyA	NM_001106643.2	0.05	1626	0.05	8.0e-06	5.57	2.48e-08	0.5	FALSE
PL	Rars2	alternative polyA	XM_006237986.5	0.05	1626	0.05	6.2e-06	-5.58	2.41e-08	0.5	FALSE
PL	Cfap206	gene expression	Cfap206	0.27	41	0.34	2.2e-38	-5.53	3.24e-08	0.46	FALSE
PL	LOC103692331	gene expression	LOC103692331	0.04	1449	0.06	1.2e-06	5.43	5.67e-08	0.39	FALSE
PL	LOC120102853	gene expression	LOC120102853	0.18	27	0.17	1.0e-17	5.5	3.88e-08	0.41	FALSE
PL	LOC134486925	gene expression	LOC134486925	0.47	35	0.24	8.2e-26	6.05	1.46e-09	0.78	FALSE
PL	Rngtt	gene expression	Rngtt	0.06	1	0.1	4.2e-11	-5.49	4.03e-08	0.57	FALSE
PL	Rars2	isoform ratio	XM_006237986.5	0.04	1626	0.04	2.4e-05	-5.47	4.61e-08	0.5	FALSE
PL	Srsf12	mRNA stability	Srsf12	0.04	1	0.05	2.1e-06	5.81	6.43e-09	0.86	FALSE
pVTA	Cfap206	gene expression	Cfap206	0.54	1585	0.67	2.1e-71	-5.47	4.46e-08	0.43	FALSE
pVTA	Cnr1	gene expression	Cnr1	0.13	1	0.08	4.0e-07	-5.41	6.32e-08	0.29	FALSE
pVTA	LOC120102853	gene expression	LOC120102853	0.02	1410	0.01	5.2e-02	5.47	4.47e-08	0.35	FALSE
pVTA	Rars2	gene expression	Rars2	0.05	1626	0.05	5.1e-05	5.33	9.76e-08	0.5	FALSE
pVTA	Srsf12	gene expression	Srsf12	0.1	1	0.13	8.1e-11	5.42	5.87e-08	0.48	FALSE
pVTA	Cfap206	isoform ratio	XM_017593532.3	0.08	7	0.07	2.1e-06	-5.74	9.19e-09	0.44	FALSE
pVTA	RGD1359108	mRNA stability	RGD1359108	0.04	1	0.03	1.2e-03	-6.1	1.07e-09	0.06	FALSE
pVTA	Srsf12	mRNA stability	Srsf12	0.18	1	0.18	2.3e-14	5.63	1.85e-08	0.74	FALSE
RMTg	Cfap206	gene expression	Cfap206	0.52	1	0.44	5.6e-13	5.22	1.83e-07	0.09	FALSE
RMTg	RGD1359108	gene expression	RGD1359108	0.23	11	0.15	9.4e-05	-5.98	2.20e-09	0.67	FALSE
RMTg	Rars2	intron excision ratio	chr5_54007886_54009608	0.12	1	0.14	2.0e-04	5.39	6.92e-08	0.05	FALSE
RMTg	Rars2	mRNA stability	Rars2	0.15	4	0.14	1.9e-04	5.68	1.32e-08	0.48	FALSE