Best TWAS P=8.694413e-08 · Best GWAS P=5.147173e-08 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Apaf1 | gene expression | ENSRNOG00000008022 | 0.10 | 0.10 | top1 | 1 | 0.10 | 1.5e-11 | 5.2 | -5.2 | 2.1e-07 | -0.93 | 0.21 | 0.79 | FALSE |
| 2 | Brain | Tmpo | alternative polyA | ENSRNOT00000113551 | 0.03 | 0.02 | top1 | 1 | 0.02 | 2.5e-03 | 5.3 | -5.3 | 1.5e-07 | -0.94 | 0.06 | 0.10 | FALSE |
| 3 | NAcc2 | Ikbip | gene expression | ENSRNOG00000008247 | 0.24 | 0.21 | top1 | 1 | 0.21 | 2.5e-11 | 5.4 | 5.4 | 8.7e-08 | 0.93 | 0.10 | 0.90 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.