Kat14

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA isoform ratio XM_039105471.1 0.07 0.05 8.6e-03 -0 0.04 0.02 -0 6.3e-01 1.0e-02 5.5e-02 3.7e-01
2 PL gene expression Kat14 0.03 0.02 4.6e-03 0 0.01 0.01 0 8.5e-02 3.6e-02 2.2e-02 1.1e-01
3 BLA mRNA stability Kat14 0.05 0.04 8.1e-03 0.04 0.03 0.03 0.02 2.7e-03 1.7e-02 8.1e-03 4.5e-02
4 Liver gene expression Kat14 0.04 0.03 4.0e-04 0.01 0.01 0 0.01 5.2e-02 2.8e-02 2.0e-01 3.6e-02
5 Adipose isoform ratio XM_039105471.1 0.03 0.02 3.2e-03 0 0 -0 -0 3.0e-01 2.2e-01 5.6e-01 5.8e-01
6 Adipose alternative TSS XM_039105471.1 0.03 0.02 3.7e-03 0 0 -0 0 2.6e-01 2.4e-01 1.0e+00 3.5e-01
7 Adipose alternative TSS XM_039105473.1 0.04 0.03 1.0e-03 0.01 0.01 0 0.01 2.2e-02 4.1e-02 1.2e-01 1.5e-02
8 Adipose alternative TSS XM_039105471.1 0.03 0.02 2.2e-03 0 0 -0 0 1.2e-01 1.3e-01 5.5e-01 9.5e-02
9 Adipose alternative TSS XM_039105472.1 0.04 0.03 1.2e-03 0.01 0.01 0 0.01 2.9e-02 5.0e-02 1.7e-01 2.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.10.20.60.30.1-0.4-0.2-0.2-0.20.7-0.70.7
Area under the delay curve1.71.74.32.1-2.0-0.80.71.21.2-1.30.5-1.2
BMI with tail2.58.218.2-2.93.74.33.92.72.5-0.12.2-0.6
BMI without tail1.83.811.1-3.03.32.52.00.90.81.00.70.7
Body weight2.410.227.0-4.75.24.23.82.01.71.41.10.9
Weight adjusted by age0.70.81.6-0.90.6-0.8-0.6-0.9-0.91.0-1.31.0
Bone surface0.20.31.2-0.91.10.80.2-0.1-0.10.50.20.4
Bone volume0.40.71.5-0.81.0-0.1-0.4-0.6-0.61.2-0.91.2
Breakpoint value in progressive ratio session0.20.20.8-0.90.80.70.2-0.1-0.10.20.30.1
Number of licking bursts0.20.20.50.7-0.5-0.30.50.60.6-0.0-0.30.1
Context. condit. distance diff. score0.10.10.3-0.30.5-0.0-0.1-0.2-0.20.5-0.40.4
Locomotion velocity, session 10.50.61.7-0.4-0.4-0.6-1.3-1.2-1.1-0.00.1-0.1
Locomotion distance, session 11.51.94.61.3-2.1-2.1-1.8-1.2-1.1-0.4-0.6-0.2
Locomotion velocity, session 21.51.85.71.5-2.4-0.9-0.5-0.00.1-1.80.9-1.6
Locomotion distance, session 22.63.67.50.5-1.3-2.7-2.7-2.3-2.30.8-1.71.0
Locomotion velocity, session 31.11.23.31.4-1.8-1.7-1.3-0.8-0.7-0.4-0.5-0.2
Locomotion distance, session 30.60.72.51.3-1.6-1.0-0.5-0.1-0.0-0.6-0.1-0.5
Stereotopy head waving bouts, day 30.10.10.4-0.60.60.3-0.3-0.4-0.40.3-0.00.2
Stereotopy head waving duration, day 30.10.20.6-0.70.80.4-0.1-0.2-0.20.30.10.2
Locomotion velocity, session 70.91.02.2-0.1-0.9-1.5-1.4-1.3-1.30.1-0.90.2
Locomotion distance, session 71.01.32.0-0.90.1-1.2-1.2-1.4-1.41.0-1.41.1
Stereotopy head waving bouts, day 70.00.00.1-0.30.20.20.10.00.0-0.20.2-0.2
Stereotopy head waving duration, day 70.10.10.30.6-0.5-0.10.00.20.2-0.50.3-0.5
Locomotion velocity, session 80.70.92.2-0.5-0.1-0.8-1.5-1.4-1.40.5-0.60.5
Locomotion distance, session 81.52.34.60.2-0.7-2.1-2.1-1.8-1.80.9-1.51.0
Degree of sensitization distance1.61.63.6-1.91.4-0.2-0.6-1.1-1.21.6-1.11.5
Degree of sensitization stereotypy0.20.20.4-0.00.10.50.70.60.5-0.40.5-0.4
Conditioned locomotion1.11.31.9-0.90.7-0.7-1.2-1.3-1.41.4-1.21.4
Cocaine response after cond. corrected1.71.94.0-0.0-0.7-2.0-1.7-1.6-1.60.9-1.71.1
Cocaine response after cond. not corrected2.83.16.60.3-0.9-2.6-2.0-1.9-1.81.3-2.31.5
Cocaine response before conditioning0.10.10.30.5-0.3-0.4-0.2-0.1-0.10.3-0.60.4
Saline control response3.34.48.6-2.92.80.1-1.1-1.8-1.82.6-1.72.4
Bone: connectivity density0.00.00.30.5-0.2-0.0-0.2-0.0-0.0-0.10.1-0.1
Bone: cortical apparent density0.91.12.01.4-0.80.70.81.11.2-1.11.1-1.1
Bone: cortical area0.20.30.8-0.10.40.90.70.70.7-0.20.6-0.3
Bone: cortical porosity0.30.41.1-0.30.71.00.70.70.60.10.6-0.0
Bone: cortical porosity0.50.51.4-0.40.81.20.90.80.70.00.7-0.1
Bone: cortical thickness1.42.33.31.1-0.41.71.51.81.8-1.51.8-1.6
Bone: cortical thickness0.60.72.41.6-1.4-0.60.00.40.5-0.70.1-0.6
Bone: cortical tissue density0.60.81.41.2-0.60.70.71.01.0-0.90.9-1.0
Condit. Reinf. active minus inactive responses0.10.10.50.2-0.1-0.6-0.2-0.2-0.20.3-0.70.4
Condit. Reinf. active-inactive response ratio0.20.20.80.3-0.2-0.8-0.2-0.2-0.20.5-0.90.6
Condit. Reinf. active responses0.10.10.50.4-0.4-0.7-0.2-0.2-0.20.0-0.50.1
Condit. Reinf. inactive responses0.10.10.2-0.4-0.10.1-0.2-0.3-0.3-0.30.3-0.3
Incentive salience index mean0.60.82.21.5-1.5-0.70.20.50.6-0.90.1-0.8
Condit. Reinf. lever presses2.12.84.92.2-2.1-0.11.21.61.6-2.11.2-1.9
Condit. Reinf. active minus inactive responses0.60.83.4-1.81.51.00.1-0.4-0.50.30.40.1
Condit. Reinf. active-inactive response ratio0.40.41.7-1.31.10.70.3-0.1-0.10.40.20.3
Condit. Reinf. active responses0.60.91.9-0.60.61.40.80.60.6-1.01.3-1.1
Condit. Reinf. inactive responses1.61.93.80.8-0.71.11.01.21.2-1.91.8-2.0
Condit. Reinf. lever presses1.21.64.5-1.92.12.01.10.50.40.20.8-0.1
Condit. Reinf. lever reinforcers received0.71.02.6-0.90.91.60.80.60.5-0.81.3-0.9
Conditioned reinforcement - actives1.71.73.1-0.70.3-1.2-1.7-1.8-1.71.0-1.31.1
Conditioned reinforcement - inactives3.64.05.8-0.90.7-1.9-2.3-2.4-2.42.1-2.32.2
Conditioned locomotion0.20.20.70.8-0.7-0.0-0.3-0.00.0-0.40.3-0.4
Patch foraging indifference point 0 sec2.23.55.7-1.81.3-1.2-2.0-2.4-2.41.8-1.81.8
Patch foraging indifference point AUC0.40.41.41.2-1.0-0.3-0.10.30.3-0.70.5-0.7
Delay disc. indifference point, 0s delay0.91.01.80.8-0.60.51.31.41.3-0.90.8-0.9
Delay disc. indifference point, 16s delay1.31.34.22.0-2.1-1.3-0.10.40.4-0.9-0.1-0.7
Delay disc. indifference point, 2s delay1.21.42.61.0-0.90.31.61.61.6-1.10.8-1.0
Delay disc. indifference point, 24s delay2.62.58.42.6-2.9-2.2-0.60.10.2-1.2-0.4-0.8
Delay disc. indifference point, 4s delay0.60.61.20.8-0.9-0.31.11.11.1-0.60.2-0.5
Delay disc. indifference point, 8s delay1.01.13.31.8-1.7-0.80.00.50.6-1.10.3-0.9
Indifference point function ln k0.81.12.0-1.30.7-0.6-1.1-1.4-1.40.8-0.90.8
Indifference point function log k0.81.12.0-1.30.7-0.6-1.1-1.4-1.40.8-0.90.8
Patch foraging total patch changes 0 sec1.93.15.2-1.51.1-1.3-2.0-2.3-2.31.7-1.71.7
Patch foraging total patch changes 12 sec0.10.10.3-0.50.30.30.20.00.0-0.10.3-0.1
Patch foraging total patch changes 18 sec1.01.32.3-0.20.2-1.2-1.5-1.4-1.41.0-1.31.1
Patch foraging total patch changes 24 sec0.20.20.3-0.20.2-0.6-0.5-0.5-0.50.5-0.60.5
Patch foraging total patch changes 6 sec0.50.71.0-0.40.3-1.0-0.9-1.0-1.00.7-1.00.7
Patch foraging time to switch 0 sec0.71.12.8-0.50.81.51.71.41.3-0.10.6-0.2
Patch foraging water rate 0 sec0.81.22.61.2-1.5-1.6-1.5-1.1-1.0-0.5-0.4-0.3
Patch foraging water rate 12 sec1.42.16.02.4-2.4-1.9-1.0-0.3-0.2-1.1-0.2-0.8
Patch foraging water rate 18 sec4.76.317.81.7-2.7-4.2-3.2-2.5-2.40.6-2.41.0
Patch foraging water rate 24 sec2.43.48.20.6-1.0-2.9-2.4-2.1-2.00.9-2.01.2
Patch foraging water rate 6 sec1.72.46.41.6-2.0-2.5-2.0-1.4-1.30.1-1.20.3
Seeking ratio, delayed vs. immediate footshock0.20.20.8-0.90.60.40.0-0.2-0.20.50.00.4
Distance traveled before self-admin0.40.40.80.1-0.30.70.60.50.5-0.90.6-0.8
Distance traveled after self-admin1.41.62.11.4-0.81.21.01.31.4-1.31.4-1.4
Extensor digitorum longus weight0.10.41.4-1.21.00.1-0.1-0.4-0.50.7-0.40.6
Bone: elastic displacement0.80.91.80.1-0.31.10.90.90.9-0.91.3-1.0
Bone: elastic work1.62.04.6-0.40.72.12.01.71.7-0.61.5-0.8
Bone: endosteal estimation1.63.58.4-2.92.6-0.0-0.1-1.0-1.12.4-1.62.3
Bone: endosteal perimeter1.53.15.2-2.22.0-0.6-0.9-1.5-1.62.3-1.82.2
Epididymis fat weight1.53.69.3-3.02.92.52.31.11.00.50.90.2
Delta time in closed arm before/after self-admin0.20.10.4-0.1-0.0-0.4-0.7-0.6-0.6-0.2-0.1-0.1
Delta time in open arm before/after self-admin0.60.61.4-0.71.21.20.90.60.50.50.20.3
Diff in mean of infusions in LGA sessions0.40.41.31.1-1.1-0.30.30.50.5-0.70.2-0.6
Delay discount exponential model param1.71.84.5-2.12.10.9-0.6-1.1-1.11.4-0.41.2
Extinction: sum of active levers before priming0.50.50.8-0.50.3-0.4-0.8-0.9-0.90.7-0.70.7
Active lever presses in extinction session 61.31.34.4-2.11.80.9-0.3-0.8-0.90.9-0.10.7
Bone: final force0.20.30.8-0.30.60.70.90.70.60.30.10.2
Bone: final moment0.10.20.6-0.40.60.60.80.50.50.30.00.3
Food consumed during 24 hour testing period0.00.10.1-0.2-0.3-0.40.20.00.0-0.3-0.1-0.2
Glucose0.81.13.6-1.91.50.3-0.4-0.9-0.91.1-0.61.0
Heart weight0.81.23.6-1.81.91.20.90.30.21.0-0.00.8
Delay discount hyperbolic model param1.51.63.7-1.91.90.8-0.8-1.1-1.21.3-0.41.1
Intermittent access intake day 1-15 change1.01.03.5-1.91.50.6-0.4-0.8-0.90.7-0.30.6
Intermittent access intake escalation0.80.82.6-1.61.20.3-0.5-0.9-1.00.7-0.50.7
Intermittent access intake escalation 21.11.13.2-1.81.60.5-0.4-0.8-0.90.9-0.70.9
Intermitt. access day 1 inactive lever presses0.00.10.2-0.0-0.2-0.4-0.3-0.3-0.2-0.1-0.1-0.1
Intermitt. access day 15 inactive lever presses2.93.16.2-2.52.30.0-1.2-1.8-1.81.9-1.51.8
Intermitt. access escalation Index1.41.24.0-1.92.01.40.3-0.1-0.20.80.30.6
Intermittent access day 1 total infusions0.10.10.5-0.2-0.00.50.30.30.3-0.40.7-0.5
Intermittent access day 15 total infusions0.50.52.3-1.51.00.7-0.2-0.6-0.60.30.10.2
Intermittent access terminal intake (last 3 days)0.40.51.7-1.30.71.00.1-0.2-0.2-0.30.7-0.4
Intermittent access total infusions0.30.41.4-1.20.90.90.0-0.3-0.30.10.40.0
Intermittent access day 1 locomotion1.11.22.00.9-0.80.80.91.21.2-1.11.4-1.2
Intermittent access day 15 total locomotion0.10.10.3-0.30.50.40.1-0.0-0.10.3-0.10.3
Intermittent access total locomotion0.30.40.50.7-0.50.40.50.60.7-0.60.7-0.6
Intermittent access standard deviation0.50.51.1-0.70.5-0.2-1.0-1.1-1.10.4-0.60.5
Left kidney weight0.51.44.1-1.82.01.51.10.50.40.90.10.7
Right kidney weight0.51.34.1-1.82.01.20.90.30.21.0-0.10.8
Cocaine induced anxiety0.70.81.3-0.70.6-0.6-1.1-1.1-1.10.9-0.80.9
Post-drug Anxiety0.91.03.6-1.91.70.2-0.1-0.6-0.71.0-0.50.9
Baseline Anxiety0.80.82.6-1.61.61.00.80.30.20.40.20.3
Tail length0.72.14.8-2.21.7-0.2-0.6-1.2-1.31.7-1.31.7
Length with tail0.72.68.3-2.92.70.90.4-0.5-0.61.8-0.81.6
Length without tail0.40.92.3-1.31.51.31.10.60.50.40.30.3
Times rat made contact with spout1.01.22.9-1.71.71.71.10.50.50.20.70.0
Lifetime Intake0.30.31.1-1.10.90.5-0.2-0.5-0.50.30.10.2
Liver weight, left0.00.00.1-0.20.0-0.00.0-0.1-0.1-0.20.1-0.2
Liver weight, right0.00.00.10.0-0.3-0.30.10.00.00.1-0.20.1
Locomotor activity0.10.20.5-0.40.70.60.30.20.20.40.00.3
Locomotor testing distance0.00.00.10.20.00.0-0.2-0.1-0.1-0.00.0-0.0
Locomotor testing rearing0.10.20.5-0.20.70.60.20.20.20.5-0.10.4
Locomotion in novel chamber1.51.92.9-0.70.4-1.4-1.7-1.7-1.71.3-1.51.4
Locomotion in novel chamber post-restriction0.70.82.10.8-0.7-1.4-1.2-0.9-0.80.4-0.80.5
Fecal boli incidents, locomotor time 12.22.44.1-0.4-0.2-2.0-1.7-1.7-1.71.4-1.91.6
Change in fecal boli incidents, locomotor task0.20.20.70.10.10.70.20.30.3-0.50.8-0.6
Time >=10cm from walls, locomotor time 10.10.10.30.2-0.3-0.6-0.5-0.4-0.40.2-0.50.3
Bouts of movement, locomotor time 11.61.75.00.4-0.9-2.2-1.4-1.3-1.20.8-1.71.0
Total resting periods, locomotor time 12.32.56.70.4-0.9-2.6-1.8-1.6-1.61.0-2.01.2
Rest time, locomotor task time 11.51.63.8-0.2-0.2-2.0-1.3-1.4-1.41.0-1.71.1
Distance moved, locomotor task time 13.13.45.22.2-2.20.71.11.71.8-2.31.9-2.2
Vertical activity count, locomotor time 10.80.81.40.4-0.31.01.21.21.2-0.80.9-0.8
Time >=10cm from walls, locomotor time 20.50.51.4-1.21.21.00.70.30.30.20.30.1
Bouts of movement, locomotor time 20.20.30.6-0.10.20.80.60.50.5-0.40.7-0.5
Total resting periods, locomotor time 20.20.20.6-0.40.50.80.40.30.3-0.20.5-0.3
Rest time, locomotor task time 20.30.30.6-0.40.1-0.6-0.5-0.6-0.60.7-0.80.7
Distance moved, locomotor task time 20.80.92.31.5-1.5-0.10.20.60.6-1.20.6-1.1
Vertical activity count, locomotor time 20.70.71.20.9-0.70.50.70.90.9-1.10.9-1.1
Light reinforcement 11.22.23.2-1.10.7-1.4-1.3-1.6-1.61.6-1.81.7
Light reinforcement 22.53.35.6-1.81.6-0.6-1.6-1.9-1.92.4-1.72.3
Bone: marrow area1.73.68.7-2.92.70.0-0.1-1.0-1.22.5-1.62.3
Bone: maximum diameter0.81.53.3-1.81.80.1-0.1-0.7-0.71.6-1.11.5
Bone: maximum force0.20.30.9-0.50.90.40.50.30.30.8-0.40.7
Bone: maximum moment0.10.30.6-0.40.80.40.50.30.30.6-0.30.6
Mean time between licks in bursts0.10.20.30.5-0.1-0.5-0.3-0.1-0.10.5-0.50.6
Mean num. licks in bursts0.60.72.9-1.71.21.10.0-0.4-0.40.20.60.0
Cd content in liver0.20.30.80.4-0.2-0.10.90.80.7-0.2-0.3-0.1
Co content in liver0.50.62.01.3-1.4-0.6-0.10.30.3-0.80.2-0.7
Cu content in liver0.30.41.00.1-0.4-1.0-0.8-0.7-0.70.1-0.60.2
Fe content in liver0.30.41.2-0.61.10.70.40.20.20.7-0.30.6
K content in liver3.02.96.62.6-2.30.00.71.41.5-2.01.5-1.9
Mg content in liver1.21.32.11.5-0.90.70.91.21.3-1.11.1-1.2
Mn content in liver1.01.22.30.0-0.1-1.2-1.5-1.3-1.31.1-1.01.1
Na content in liver3.63.85.51.7-1.01.81.72.12.2-2.12.3-2.2
Rb content in liver0.50.71.51.2-0.9-0.10.70.90.9-0.90.3-0.8
Se content in liver0.70.81.10.9-1.00.20.91.01.0-1.00.8-1.0
Sr content in liver0.60.50.8-0.1-0.1-0.9-0.9-0.9-0.80.6-0.80.7
Zn content in liver0.20.20.60.8-0.7-0.10.30.50.5-0.30.2-0.3
Bone: minimum diameter0.30.51.6-1.11.30.90.50.10.10.50.10.4
Time in familiar zone, hab. session 11.81.73.01.0-1.10.51.21.31.3-1.71.3-1.7
Time in novel zone, hab. session 11.91.94.2-1.31.6-0.1-0.7-1.0-1.02.1-1.42.0
Total zone transitions, hab. session 10.40.51.70.7-1.3-1.0-0.8-0.5-0.5-0.5-0.1-0.3
Total locomotion distance, hab. session 10.60.82.20.8-1.5-1.2-1.2-0.8-0.7-0.6-0.1-0.5
Locomotion velocity, hab. session 10.81.13.31.2-1.8-1.3-1.2-0.7-0.6-0.90.0-0.7
Time in familiar zone, hab. session 20.10.20.3-0.10.4-0.1-0.5-0.5-0.50.5-0.30.4
Time in novel zone, hab. session 20.20.20.6-0.80.60.40.40.10.10.2-0.00.2
Total zone transitions, hab. session 20.60.71.1-0.80.4-0.6-0.9-1.0-1.00.9-0.80.9
Total locomotion distance, hab. session 21.82.43.8-1.20.9-1.1-1.8-1.9-1.91.6-1.41.6
Locomotion velocity, hab. session 21.52.03.6-0.70.3-1.3-1.9-1.9-1.81.3-1.31.3
Novel to familiar place preference ratio0.30.30.8-0.10.6-0.30.0-0.1-0.10.9-0.80.9
Novelty place preference0.20.20.50.10.4-0.20.20.10.10.7-0.70.7
Time in novel zone, NPP test0.40.41.0-0.30.9-0.00.30.10.11.0-0.81.0
Total zone transitions, NPP test0.30.51.20.3-0.9-1.1-0.9-0.7-0.70.1-0.60.2
Total locomotion distance, NPP test1.52.13.8-0.3-0.2-1.7-1.9-1.8-1.81.2-1.51.3
Locomotion velocity, NPP test1.41.93.80.1-0.6-1.8-2.0-1.7-1.70.9-1.41.0
Intraocular pressure3.04.29.1-0.3-0.3-3.0-2.1-2.1-2.11.9-2.62.1
Delta distance traveled before/after self-admin1.61.72.91.7-0.60.91.31.71.7-1.11.4-1.2
Delta ambulatory time before/after self-admin0.60.71.71.3-0.40.50.81.11.1-0.40.7-0.5
Parametrial fat weight4.28.119.3-3.94.04.43.32.01.80.12.2-0.4
Pavlov. Cond. lever latency3.03.99.6-3.13.00.8-0.8-1.5-1.62.2-1.02.0
Pavlov. Cond. magazine entry latency1.31.72.41.5-1.10.81.21.51.6-1.41.3-1.4
Pavlov. Cond. change in total contacts4.34.611.53.4-3.2-0.71.01.81.9-2.41.1-2.1
Pavlov. Cond. index score3.64.68.62.9-2.60.31.52.12.2-2.51.7-2.4
Pavlov. Cond. latency score3.54.510.23.2-2.8-0.21.21.92.0-2.51.5-2.3
Pavlov. Cond. lever contacts2.83.36.32.5-2.5-0.31.11.61.7-2.21.2-2.0
Pavlov. Cond. magazine entry number1.82.33.2-1.51.2-0.9-1.5-1.8-1.81.7-1.41.7
Pavlov. Cond. intertrial magazine entries4.25.17.9-1.91.5-1.5-2.5-2.8-2.82.3-2.22.3
Pavlov. Cond. lever-magazine prob. diff.4.15.19.13.0-2.50.51.72.32.4-2.51.8-2.4
Pavlov. Cond. response bias2.53.04.52.1-1.90.41.51.91.9-2.01.4-1.9
Pavlov. Cond. lever latency1.31.83.71.9-1.9-1.9-1.8-1.0-0.9-0.0-0.70.1
Pavlov. Cond. magazine entry latency2.32.68.1-2.82.60.5-0.3-1.1-1.21.7-0.91.5
Pavlov. Cond. change in total contacts2.12.97.1-1.81.92.72.11.41.3-0.71.7-0.9
Pavlov. Cond. index score1.62.16.3-2.52.52.01.40.50.40.50.50.3
Pavlov. Cond. latency score1.21.54.1-2.02.01.71.30.60.40.30.50.1
Pavlov. Cond. lever contacts1.11.53.3-1.71.81.71.60.90.80.00.7-0.1
Pavlov. Cond. magazine entry number1.41.76.72.6-2.4-1.3-0.50.20.4-0.80.0-0.7
Pavlov. Cond. intertrial magazine entries0.70.93.71.9-1.7-0.8-0.10.40.5-0.6-0.0-0.5
Pavlov. Cond. lever-magazine prob. diff.1.82.35.5-2.32.32.21.70.90.70.10.9-0.1
Pavlov. Cond. response bias1.41.96.7-2.62.51.61.00.20.10.70.20.5
Time in closed arm before self-admin0.50.61.0-0.80.2-0.3-0.9-1.0-1.00.8-0.80.9
Time in closed arm after self-admin1.11.12.6-0.80.1-0.8-1.6-1.6-1.60.5-0.80.6
Time in open arm before self-admin1.01.11.90.8-0.11.01.21.41.4-0.81.3-0.9
Time in open arm after self-admin2.52.85.50.30.52.32.12.02.0-1.12.0-1.3
Bone: periosteal estimation0.81.74.2-2.02.10.50.2-0.4-0.51.7-0.91.5
Bone: periosteal perimeter0.60.91.9-1.41.40.1-0.3-0.6-0.71.3-0.71.2
Bone: post-yield work0.30.50.8-0.50.7-0.4-0.4-0.6-0.60.9-0.90.9
Progressive ratio test 1 active lever presses0.10.10.3-0.20.20.60.40.30.3-0.10.6-0.2
Progressive ratio test 1 breakpoint0.40.40.9-0.20.10.80.70.60.6-0.50.9-0.6
Progressive ratio test 1 inactive lever presses1.61.82.9-1.21.2-0.8-1.0-1.3-1.31.7-1.51.7
Progressive ratio test 2 active lever presses0.00.00.1-0.30.30.00.0-0.1-0.10.2-0.20.2
Progressive ratio test 2 breakpoint0.00.00.1-0.30.30.20.20.10.00.10.10.1
Progressive ratio test 2 inactive lever presses2.73.15.3-2.12.2-0.4-1.0-1.5-1.62.3-1.72.2
Incentive Sensitization - Responses0.60.61.1-0.70.9-0.3-0.5-0.6-0.71.0-0.81.0
Incentive Sensitization - Breakpoint0.60.61.1-0.81.0-0.0-0.4-0.6-0.61.0-0.71.0
Sum of active levers in priming session hrs 5-60.90.81.9-0.1-0.4-1.1-1.4-1.2-1.20.4-0.90.5
Progressive ratio1.31.53.10.0-0.1-1.8-1.7-1.5-1.50.9-1.21.0
Food seeking constrained by brief footshock2.02.44.72.2-2.1-0.20.20.91.0-2.11.6-2.0
Seeking ratio, punishment vs. effort3.03.65.00.9-0.62.12.22.22.2-1.92.2-2.0
Retroperitoneal fat weight3.913.026.6-4.24.65.25.03.33.00.12.4-0.4
Reaction time number correct2.23.15.2-0.30.1-2.1-1.9-1.9-1.91.9-2.32.0
Reaction time mean minus median0.91.13.0-1.71.71.60.90.40.30.10.8-0.1
Reaction time mean minus median AUC0.81.03.5-1.91.91.20.60.0-0.00.60.30.4
Reaction time num false alarms0.71.02.10.7-1.4-1.3-1.4-1.1-1.0-0.4-0.4-0.2
Reaction time num false alarms AUC0.60.81.80.8-1.3-1.2-1.2-0.9-0.8-0.3-0.4-0.1
Reaction time trials correct on left2.23.15.2-0.30.1-2.1-1.9-1.9-1.91.9-2.32.0
Reaction time trials on left2.33.35.4-0.30.3-2.1-1.9-1.9-1.92.0-2.32.1
Reaction time mean1.21.64.4-2.12.01.81.30.60.50.20.8-0.0
Reaction time mean AUC1.01.43.4-1.81.71.71.30.60.5-0.00.9-0.2
Median of all reaction times0.91.33.4-1.81.71.61.30.60.50.10.7-0.1
Reaction time omissions0.50.72.3-1.11.50.50.3-0.0-0.11.1-0.41.0
Reaction time false alarm rate0.30.41.30.7-1.1-0.3-0.4-0.1-0.1-0.90.5-0.8
Reaction time premature initiation rate0.20.30.5-0.50.1-0.6-0.6-0.7-0.70.4-0.50.4
Reaction time premature initiations1.21.82.7-0.60.0-1.6-1.6-1.6-1.61.2-1.51.3
Std. dev. reaction times0.91.23.1-1.81.71.61.10.50.40.10.7-0.0
Reaction time trials completed2.33.35.4-0.30.3-2.1-1.9-1.9-1.92.0-2.32.1
Reaction time trials AUC2.94.26.9-0.60.5-2.3-2.2-2.2-2.22.3-2.62.4
Run reversals in cocaine runway, females1.00.92.1-0.91.41.41.30.90.80.40.60.2
Run reversals in cocaine runway, males3.02.94.40.4-0.12.02.12.02.0-1.72.0-1.8
Latency to leave start box in cocaine runway0.80.91.5-0.80.7-0.3-1.2-1.2-1.21.0-0.60.9
Latency to leave start box in cocaine runway, F1.41.52.2-1.51.2-0.4-1.0-1.3-1.31.4-1.11.4
Latency to leave start box in cocaine runway, M0.50.51.20.8-0.60.5-0.20.20.3-0.81.1-0.9
Std. dev. time between licks in bursts0.40.51.21.0-1.0-1.1-0.5-0.2-0.20.2-0.70.3
Total sessions with >9 infusions0.30.30.7-0.60.70.80.60.40.4-0.10.7-0.2
Short access day 1 total inactive lever presses3.64.05.9-1.61.3-1.5-2.2-2.4-2.42.1-2.12.1
Short access day 10 total inactive lever presses0.91.01.8-1.31.3-0.1-0.4-0.8-0.81.3-0.91.2
Short access day 1 total infusions0.91.01.7-0.60.5-1.0-1.3-1.3-1.30.9-1.00.9
Short access day 10 total infusions0.10.10.3-0.50.30.4-0.1-0.2-0.2-0.20.4-0.3
Short access total infusions0.10.20.6-0.70.70.60.1-0.1-0.10.00.4-0.1
Short access day 1 locomotion0.20.20.6-0.30.80.80.30.20.20.20.30.1
Short access day 10 total locomotion0.30.31.00.8-1.0-1.0-0.3-0.1-0.10.0-0.60.2
Short access total locomotion0.90.91.41.0-0.60.70.91.11.1-0.91.2-1.0
One hour access (0.3 mA shock)0.10.20.60.0-0.2-0.3-0.8-0.7-0.6-0.0-0.10.0
Compulsive drug intake0.60.61.50.4-0.4-0.9-1.2-1.0-0.90.4-0.80.5
One hour access (shock baseline)0.20.20.7-0.30.30.80.50.30.3-0.30.4-0.3
Social response proportion1.92.05.4-1.31.52.31.71.31.2-0.31.6-0.6
Social responses0.10.10.2-0.20.00.30.50.30.3-0.30.3-0.3
Social time0.81.01.9-0.30.61.31.41.21.1-0.61.2-0.8
Soleus weight0.10.30.5-0.50.5-0.3-0.1-0.3-0.30.6-0.70.7
Bone: stiffness0.30.51.2-0.61.0-0.1-0.1-0.3-0.31.1-0.91.1
Tibialis anterior weight0.20.81.7-1.11.31.21.20.80.70.10.4-0.0
Time to tail flick, vehicle, before self-admin3.43.49.0-3.02.70.4-0.8-1.5-1.62.1-1.01.9
Time to tail flick, vehicle, after self-admin0.40.51.70.5-1.3-1.0-0.5-0.4-0.4-0.6-0.4-0.4
Time to tail flick, test, before self-admin0.30.30.70.2-0.8-0.8-0.5-0.4-0.4-0.80.2-0.7
Time to tail flick, test, after self-admin4.54.66.5-1.81.4-1.3-2.2-2.5-2.52.3-2.52.4
Delta time to tail flick, vehicle, before/after SA1.41.44.61.7-2.1-1.7-0.4-0.1-0.0-1.0-0.6-0.7
Delta time to tail flick, test, before/after SA2.72.44.4-1.21.3-0.6-1.2-1.4-1.52.1-1.92.1
Tibia length0.82.35.1-1.91.72.31.91.21.1-0.31.5-0.6
Ambulatory time before self-admin0.30.30.8-0.20.10.90.60.40.4-0.70.6-0.7
Ambulatory time after self-admin1.31.42.41.6-0.90.91.01.31.4-1.21.1-1.2
Bone: tissue strength0.60.51.4-0.30.51.01.21.00.9-0.10.6-0.2
Total heroin consumption2.02.33.5-1.20.9-0.9-1.7-1.9-1.91.7-1.51.7
Bone: trabecular number0.10.10.60.7-0.4-0.3-0.20.00.00.3-0.30.3
Bone: trabecular spacing0.60.81.7-0.70.81.31.20.90.8-0.50.9-0.6
Bone: trabecular thickness0.00.00.10.4-0.4-0.2-0.1-0.00.0-0.0-0.1-0.0
Bone: trabecular tissue density1.01.42.60.7-0.11.21.61.61.6-0.91.1-0.9
Water consumed over 24 hours1.11.32.4-1.61.2-0.3-0.8-1.2-1.21.2-1.01.2
Number of responses in last shaping day1.51.52.7-0.60.5-1.2-1.3-1.4-1.41.2-1.61.3