Hub : Genes

Cacul1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio NM_001014248.2 0.02 0.02 6.1e-03 0.01 0.01 0.01 0.01 3.5e-02 1.3e-02 6.2e-02 1.5e-02
2 Brain isoform ratio NM_001416001.1 0.1 0.05 8.1e-08 0.08 0.08 0.07 0.08 3.5e-08 8.6e-08 3.5e-07 1.1e-07
3 Brain intron excision ratio chr1_269663603_269672274 0.11 0.06 6.8e-09 0.08 0.07 0.08 0.07 4.3e-08 1.5e-07 6.8e-08 2.0e-07
4 NAcc isoform ratio NM_001014248.2 0.16 0.1 1.6e-06 0.05 0.04 0.03 0.03 9.7e-08 4.4e-06 2.0e-05 6.2e-05
5 IC isoform ratio NM_001014248.2 0.1 0.06 1.5e-03 0.04 0.03 0.04 0.04 9.5e-03 1.7e-02 9.3e-03 8.5e-03
6 Brain isoform ratio NM_001014248.2 0.11 0.06 2.1e-08 0.1 0.08 0.1 0.09 3.1e-09 7.3e-08 1.6e-09 2.2e-08
7 IC isoform ratio NM_001416001.1 0.1 0.06 1.1e-03 0.06 0.04 0.05 0.04 1.1e-03 1.2e-02 4.9e-03 6.1e-03
8 Liver isoform ratio NM_001014248.2 0.03 0.02 8.7e-03 0 0.01 0.01 0.01 7.7e-02 7.0e-03 3.7e-02 4.0e-02
9 PL isoform ratio XM_063270019.1 0.04 0.03 1.7e-03 0.02 0.02 0.01 0.02 2.2e-03 1.4e-03 2.3e-02 4.2e-03
10 PL alternative TSS XM_063270019.1 0.04 0.03 2.2e-03 0.01 0.01 0 0.01 1.1e-02 7.7e-03 3.7e-01 1.3e-02
11 NAcc gene expression Cacul1 0.12 0.06 9.6e-12 0.09 0.08 0.08 0.09 8.7e-14 3.9e-12 7.6e-12 4.9e-13
12 Adipose gene expression Cacul1 0.13 0.07 6.1e-11 0.08 0.09 0.09 0.09 2.7e-09 3.3e-10 1.1e-09 2.5e-10
13 BLA isoform ratio NM_001014248.2 0.09 0.06 2.6e-03 0.01 0.02 0.02 0.02 6.9e-02 3.1e-02 3.7e-02 3.1e-02
14 BLA isoform ratio XM_063270019.1 0.07 0.04 8.8e-03 -0 -0 0 0.01 6.2e-01 4.0e-01 2.3e-01 1.1e-01
15 PL gene expression Cacul1 0.04 0.03 7.2e-03 0.03 0.01 -0 0.01 7.2e-04 7.1e-02 4.1e-01 1.2e-02
16 Adipose alternative TSS XM_063270019.1 0.04 0.03 2.1e-03 0.02 0.01 0.02 0.01 5.0e-03 1.0e-02 6.1e-03 1.1e-02
17 Adipose isoform ratio XM_063270019.1 0.04 0.03 2.1e-03 0.02 0.01 0.01 0.01 6.3e-03 1.9e-02 9.4e-03 1.4e-02
18 BLA gene expression Cacul1 0.07 0.04 7.8e-03 0.01 0.02 -0 0.01 8.2e-02 3.5e-02 6.8e-01 8.7e-02
19 Brain gene expression Cacul1 0.07 0.04 4.7e-06 0.01 0.06 0.05 0.04 1.3e-02 4.3e-06 2.3e-05 1.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density4.06.912.43.3-3.53.53.53.12.5-2.22.8-2.9-3.0-2.9-2.50.8-1.6-1.5-2.2-2.2-2.2-1.4
Area under the delay curve1.11.36.0-0.20.2-0.2-0.20.40.6-0.90.10.50.81.01.32.1-0.5-0.52.52.51.40.8
BMI with tail20.470.3158.112.6-12.212.212.212.310.6-10.89.9-7.9-7.1-5.8-4.86.1-4.1-4.4-2.2-2.2-1.80.1
BMI without tail13.942.695.79.8-9.59.59.59.58.3-8.37.7-6.2-5.6-4.7-3.64.4-3.1-3.5-1.9-1.9-1.40.0
Body weight19.183.7173.813.2-13.113.113.112.911.2-11.310.9-9.2-8.4-7.3-6.06.2-5.4-5.5-2.7-2.7-3.0-1.2
Weight adjusted by age2.63.99.93.0-3.13.13.23.02.2-2.72.1-1.6-1.4-1.0-0.90.6-0.3-0.8-1.2-1.2-0.10.4
Bone surface2.95.310.72.9-3.33.33.33.02.6-2.32.5-2.4-2.4-2.4-1.80.8-1.2-1.4-1.5-1.5-1.6-1.0
Bone volume4.37.816.83.9-4.14.14.13.93.2-3.13.0-2.8-2.7-2.5-1.91.8-1.5-1.4-1.5-1.5-1.3-0.6
Breakpoint value in progressive ratio session1.72.04.81.6-1.41.41.42.01.6-2.21.8-1.5-1.1-0.3-0.81.6-1.8-1.60.90.90.0-0.3
Number of licking bursts0.40.72.00.3-0.30.30.30.40.7-0.41.0-1.1-1.1-1.0-1.00.2-1.4-1.30.40.4-1.0-1.3
Context. condit. distance diff. score0.20.30.60.3-0.40.40.40.50.7-0.10.4-0.3-0.5-0.6-0.6-0.7-0.0-0.2-0.8-0.8-0.6-0.4
Locomotion velocity, session 10.70.82.6-1.61.0-1.0-1.1-1.4-1.11.3-1.10.80.6-0.10.6-1.20.70.1-0.0-0.0-0.2-0.4
Locomotion distance, session 11.72.24.1-1.91.5-1.5-1.6-1.6-1.41.4-2.02.01.81.41.8-0.61.71.40.40.41.00.9
Locomotion velocity, session 21.21.42.6-1.41.2-1.2-1.2-1.4-1.61.5-1.61.41.20.91.0-1.31.41.3-0.1-0.10.60.6
Locomotion distance, session 20.40.51.30.8-0.90.90.90.90.2-0.6-0.10.40.30.40.70.21.00.9-0.6-0.60.61.1
Locomotion velocity, session 31.31.53.6-1.81.5-1.5-1.5-1.6-1.91.3-1.51.31.11.00.8-1.00.80.90.40.40.30.2
Locomotion distance, session 30.70.82.2-1.21.0-1.0-1.0-1.1-1.51.1-1.21.00.80.60.5-0.90.90.8-0.4-0.40.10.1
Stereotopy head waving bouts, day 31.01.22.6-1.11.0-1.0-1.0-1.0-1.20.7-1.41.51.41.21.60.41.10.90.80.81.21.0
Stereotopy head waving duration, day 31.41.63.3-1.21.4-1.4-1.4-1.1-0.70.5-1.11.41.61.51.70.60.60.51.81.81.51.0
Locomotion velocity, session 70.10.10.30.2-0.30.30.30.30.5-0.30.3-0.2-0.2-0.1-0.5-0.6-0.2-0.10.10.1-0.2-0.2
Locomotion distance, session 70.81.02.61.2-1.41.41.41.10.6-0.60.6-0.7-0.8-0.6-1.1-0.80.20.4-1.6-1.6-0.60.0
Stereotopy head waving bouts, day 71.72.09.9-1.01.1-1.1-1.1-0.40.5-0.5-0.20.91.10.91.71.9-0.4-1.03.13.11.30.4
Stereotopy head waving duration, day 71.92.312.2-1.31.4-1.4-1.4-0.60.5-0.3-0.10.50.80.61.42.0-1.1-1.53.53.50.9-0.3
Locomotion velocity, session 80.70.83.0-1.20.9-0.9-0.9-1.2-0.71.5-0.70.2-0.2-0.6-0.3-1.70.40.2-0.9-0.9-1.1-1.0
Locomotion distance, session 80.60.84.1-0.1-0.30.30.3-0.1-0.30.7-0.30.0-0.3-0.7-0.4-2.01.00.6-1.9-1.9-1.0-0.4
Degree of sensitization distance2.12.14.62.2-2.02.02.01.81.8-1.31.7-1.6-1.5-1.2-1.5-0.1-0.7-0.5-1.2-1.2-0.8-0.3
Degree of sensitization stereotypy1.51.68.4-0.30.5-0.5-0.50.21.4-1.00.7-0.10.20.20.82.2-1.2-1.62.92.90.6-0.3
Conditioned locomotion0.20.20.6-0.40.7-0.7-0.7-0.50.10.3-0.20.20.30.30.20.7-0.4-0.20.80.80.2-0.1
Cocaine response after cond. corrected3.44.110.4-1.61.5-1.5-1.5-2.1-3.02.5-2.72.21.91.71.2-2.22.73.2-1.5-1.50.81.6
Cocaine response after cond. not corrected3.94.611.3-2.12.1-2.1-2.1-2.7-3.43.1-2.61.91.51.20.8-3.02.32.7-1.4-1.40.20.7
Cocaine response before conditioning1.01.24.2-0.50.6-0.6-0.6-0.70.00.70.7-1.2-1.2-1.4-1.3-1.2-1.3-1.6-0.1-0.1-1.6-2.1
Saline control response1.11.52.4-1.31.6-1.6-1.6-1.4-1.41.2-1.41.31.41.41.2-0.10.71.21.01.01.00.9
Bone: connectivity density1.01.62.51.2-1.51.51.51.21.0-0.71.2-1.3-1.5-1.6-1.6-0.2-0.7-0.6-1.6-1.6-1.5-1.0
Bone: cortical apparent density5.77.715.5-3.73.5-3.5-3.5-3.7-3.93.8-3.62.82.42.21.6-2.42.12.80.00.00.70.7
Bone: cortical area8.613.127.15.2-5.05.05.05.14.7-4.54.4-3.7-3.3-2.6-2.52.7-2.4-2.3-1.2-1.2-1.1-0.5
Bone: cortical porosity0.60.71.11.0-1.11.11.11.00.7-0.91.0-1.0-0.9-0.7-0.70.5-0.8-0.7-0.3-0.3-0.5-0.5
Bone: cortical porosity2.02.13.61.8-1.91.91.91.91.6-1.91.8-1.6-1.5-1.2-1.01.2-1.3-1.3-0.1-0.1-0.7-0.6
Bone: cortical thickness4.47.318.14.3-3.93.93.94.03.3-3.43.2-2.6-2.3-1.5-1.81.9-1.4-1.1-1.2-1.2-0.40.3
Bone: cortical thickness2.73.28.62.9-2.42.42.42.81.9-2.91.6-0.8-0.30.50.12.5-0.40.10.40.41.41.8
Bone: cortical tissue density6.08.216.5-3.83.7-3.7-3.7-3.8-4.14.0-3.62.82.42.21.6-2.62.12.80.00.00.60.5
Condit. Reinf. active minus inactive responses0.91.14.2-0.3-0.20.20.2-0.4-0.41.0-0.2-0.3-0.7-1.1-0.9-1.90.50.2-2.0-2.0-1.5-1.1
Condit. Reinf. active-inactive response ratio0.80.94.0-1.10.7-0.7-0.7-1.2-0.81.4-0.70.3-0.1-0.6-0.2-2.00.70.1-1.2-1.2-1.0-0.9
Condit. Reinf. active responses2.22.76.81.6-2.02.02.11.40.9-0.61.1-1.5-1.8-1.9-1.8-0.8-0.1-0.1-2.6-2.6-1.9-1.0
Condit. Reinf. inactive responses3.84.69.32.9-3.03.03.02.81.8-1.92.2-2.3-2.3-1.9-2.10.9-1.1-0.5-2.0-2.0-1.6-0.8
Incentive salience index mean0.91.25.30.1-0.70.70.70.1-0.30.6-0.1-0.3-0.7-1.1-0.8-2.00.90.5-2.3-2.3-1.4-0.7
Condit. Reinf. lever presses0.40.62.80.3-0.70.70.70.3-0.30.2-0.2-0.1-0.4-0.5-0.4-1.20.90.8-1.7-1.7-0.7-0.1
Condit. Reinf. active minus inactive responses1.72.23.61.5-1.71.71.71.61.6-1.51.9-1.8-1.7-1.8-1.41.0-1.6-1.9-0.1-0.1-1.1-1.2
Condit. Reinf. active-inactive response ratio1.51.73.41.4-1.51.51.51.61.5-1.81.7-1.3-1.2-1.2-0.71.2-1.4-1.80.70.7-0.3-0.6
Condit. Reinf. active responses2.83.96.32.1-2.12.12.12.12.4-1.92.5-2.3-2.3-2.2-1.91.6-2.2-2.2-0.4-0.4-1.5-1.5
Condit. Reinf. inactive responses1.52.02.91.5-1.51.51.51.41.7-1.01.7-1.7-1.7-1.7-1.50.9-1.4-1.3-0.9-0.9-1.3-1.1
Condit. Reinf. lever presses1.72.44.32.1-1.91.91.92.01.9-1.62.0-1.8-1.7-1.3-1.41.4-1.6-1.0-0.2-0.2-0.8-0.6
Condit. Reinf. lever reinforcers received2.02.84.51.7-1.71.71.71.61.8-1.22.1-2.1-2.1-2.1-1.91.1-1.9-1.8-0.6-0.6-1.6-1.5
Conditioned reinforcement - actives1.42.45.2-2.21.9-1.9-1.7-2.0-2.31.9-2.11.71.40.71.5-1.21.61.00.40.40.50.3
Conditioned reinforcement - inactives0.40.61.3-1.01.2-1.2-1.0-1.0-1.00.9-0.50.20.20.40.00.2-0.6-0.10.90.9-0.2-0.5
Conditioned locomotion2.63.36.4-2.52.2-2.2-2.1-2.4-2.42.4-2.42.01.70.81.9-1.41.91.40.60.60.60.4
Patch foraging indifference point 0 sec2.64.912.23.5-3.03.02.93.42.9-3.12.6-2.0-1.6-0.7-1.12.5-1.3-0.90.10.10.10.5
Patch foraging indifference point AUC0.30.41.40.10.7-0.7-0.7-0.20.20.00.2-0.10.20.9-0.21.2-1.10.10.90.90.50.2
Delay disc. indifference point, 0s delay0.30.30.90.5-0.70.70.70.80.1-0.90.10.30.40.40.60.70.50.10.40.40.80.9
Delay disc. indifference point, 16s delay0.91.05.0-0.40.4-0.4-0.40.11.1-0.50.20.40.60.31.11.8-0.5-1.12.22.20.90.2
Delay disc. indifference point, 2s delay1.01.12.7-0.60.4-0.4-0.4-0.1-0.4-0.4-0.91.31.41.51.61.00.90.61.51.51.61.3
Delay disc. indifference point, 24s delay1.01.15.30.0-0.10.10.10.60.6-1.10.20.30.60.81.02.1-0.7-0.52.32.31.20.7
Delay disc. indifference point, 4s delay0.91.04.7-0.2-0.00.0-0.10.30.4-0.90.00.50.70.81.21.8-0.4-0.52.22.21.20.6
Delay disc. indifference point, 8s delay1.01.25.0-0.50.7-0.7-0.8-0.1-0.1-0.2-0.30.81.01.31.21.7-0.40.12.22.21.30.8
Indifference point function ln k0.40.72.01.0-1.31.31.30.90.3-0.50.4-0.3-0.5-0.8-0.3-0.60.80.3-1.4-1.4-0.30.2
Indifference point function log k0.40.72.01.0-1.31.31.30.90.3-0.50.4-0.3-0.5-0.8-0.3-0.60.80.3-1.4-1.4-0.30.2
Patch foraging total patch changes 0 sec3.15.914.83.8-3.33.33.33.73.2-3.42.9-2.2-1.7-0.8-1.22.8-1.5-1.00.00.00.20.6
Patch foraging total patch changes 12 sec2.22.97.22.7-2.02.02.02.52.3-2.22.2-1.8-1.4-0.5-1.12.1-1.6-0.80.10.1-0.10.1
Patch foraging total patch changes 18 sec1.52.35.02.2-1.81.81.72.21.7-1.81.9-1.7-1.4-0.6-1.31.8-1.8-0.70.10.1-0.3-0.2
Patch foraging total patch changes 24 sec0.40.72.91.0-0.10.10.10.80.7-0.71.0-0.9-0.50.6-0.71.7-1.70.00.90.90.20.1
Patch foraging total patch changes 6 sec2.23.38.62.9-1.81.81.82.52.3-2.32.5-2.0-1.40.0-1.52.6-2.3-0.70.40.40.10.3
Patch foraging time to switch 0 sec0.51.03.1-1.81.2-1.2-1.2-1.4-1.71.4-1.30.90.60.10.7-1.10.50.30.20.2-0.2-0.4
Patch foraging water rate 0 sec1.12.36.82.6-1.91.91.92.32.3-2.11.8-1.2-0.9-0.3-0.71.9-0.6-0.4-0.3-0.30.40.7
Patch foraging water rate 12 sec1.42.85.72.3-2.22.22.22.32.3-2.42.1-1.6-1.3-1.1-0.91.8-1.2-1.20.30.3-0.2-0.0
Patch foraging water rate 18 sec0.50.82.01.4-1.21.21.21.20.8-1.20.40.10.30.30.40.80.80.7-0.4-0.40.91.4
Patch foraging water rate 24 sec1.82.66.92.6-2.32.32.32.41.8-2.41.1-0.3-0.00.30.32.10.50.6-0.3-0.31.31.9
Patch foraging water rate 6 sec0.91.44.12.0-1.71.71.81.71.3-1.61.0-0.7-0.5-0.2-0.11.30.00.3-0.6-0.60.40.9
Seeking ratio, delayed vs. immediate footshock3.64.311.1-2.82.7-2.7-2.7-2.9-2.63.3-2.41.61.10.80.3-2.61.31.8-1.2-1.2-0.7-0.5
Distance traveled before self-admin3.64.78.0-2.22.1-2.1-2.1-1.9-2.71.6-2.82.82.72.52.4-1.02.72.40.50.52.02.0
Distance traveled after self-admin3.24.07.5-2.32.3-2.3-2.3-2.2-2.71.7-2.52.32.32.51.6-1.21.92.00.30.31.51.3
Extensor digitorum longus weight1.14.39.63.1-2.82.82.82.72.6-2.32.5-2.2-2.0-1.7-1.41.3-1.3-1.2-1.2-1.2-0.8-0.3
Bone: elastic displacement0.50.61.5-0.40.6-0.6-0.6-0.4-0.7-0.1-0.60.81.01.01.10.80.40.40.80.81.21.0
Bone: elastic work1.21.54.61.1-1.11.11.11.50.4-1.7-0.00.71.01.21.51.60.90.70.70.72.02.1
Bone: endosteal estimation1.53.37.52.3-2.72.72.72.62.2-2.41.9-1.6-1.6-1.7-1.01.2-0.9-1.3-0.6-0.6-0.7-0.4
Bone: endosteal perimeter1.94.19.02.6-2.62.62.62.93.0-3.02.3-1.6-1.3-1.3-0.52.6-1.3-1.80.60.60.10.0
Epididymis fat weight23.580.5159.312.6-11.811.811.912.111.2-10.511.3-9.8-8.9-7.3-7.25.9-7.1-6.3-2.4-2.4-3.8-2.4
Delta time in closed arm before/after self-admin0.50.51.70.1-0.60.60.60.1-0.6-0.0-0.50.40.20.10.0-1.01.11.0-1.3-1.30.10.6
Delta time in open arm before/after self-admin3.23.27.21.1-0.80.80.80.91.9-0.72.2-2.4-2.4-2.4-2.3-0.2-2.4-2.7-0.8-0.8-2.1-2.4
Diff in mean of infusions in LGA sessions0.50.61.80.5-0.10.10.10.80.6-1.20.7-0.30.00.70.11.3-1.0-0.91.21.20.70.3
Delay discount exponential model param1.41.57.00.2-0.20.20.3-0.4-0.50.90.0-0.7-1.0-1.2-1.4-2.30.40.4-2.7-2.7-1.6-0.9
Extinction: sum of active levers before priming0.70.71.81.0-0.90.90.91.11.0-1.31.2-1.0-0.8-0.4-0.80.8-1.2-1.00.20.2-0.3-0.4
Active lever presses in extinction session 61.11.13.71.4-0.90.90.91.30.9-1.90.9-0.40.11.10.31.7-0.5-0.21.11.11.21.0
Bone: final force5.48.620.04.5-4.54.54.54.43.6-4.03.2-2.5-2.2-1.8-1.22.3-1.0-1.2-1.0-1.0-0.20.5
Bone: final moment5.99.521.84.6-4.74.74.74.63.7-4.13.3-2.7-2.5-2.1-1.52.2-1.2-1.3-1.2-1.2-0.50.2
Food consumed during 24 hour testing period0.30.51.00.8-1.01.01.00.80.1-0.50.5-0.6-0.6-0.6-0.6-0.60.2-0.0-0.9-0.9-0.4-0.1
Glucose4.46.915.53.2-2.92.92.93.53.9-3.73.4-2.6-2.1-1.8-1.33.0-2.6-2.91.11.1-0.3-0.6
Heart weight10.816.733.75.6-5.85.85.75.64.8-5.15.0-4.2-3.9-3.5-2.91.8-2.2-3.1-1.6-1.6-1.6-1.0
Delay discount hyperbolic model param1.51.67.40.2-0.20.20.3-0.4-0.41.00.1-0.7-1.1-1.3-1.5-2.30.40.4-2.7-2.7-1.6-1.0
Intermittent access intake day 1-15 change0.51.01.5-1.11.2-1.2-1.2-1.1-1.10.8-1.11.11.21.01.1-0.10.70.50.90.90.90.7
Intermittent access intake escalation0.20.50.8-0.90.9-0.9-0.9-0.8-0.80.6-0.80.80.80.50.8-0.10.40.10.80.80.60.3
Intermittent access intake escalation 20.10.10.3-0.30.1-0.1-0.2-0.3-0.30.2-0.30.20.2-0.00.3-0.50.4-0.1-0.1-0.10.20.2
Intermitt. access day 1 inactive lever presses0.51.85.01.4-1.11.11.11.31.3-1.31.8-1.8-1.6-1.0-1.80.8-2.2-1.6-0.0-0.0-1.0-1.1
Intermitt. access day 15 inactive lever presses0.30.62.10.7-0.30.30.30.80.9-1.10.7-0.4-0.00.4-0.01.4-0.9-0.61.11.10.70.4
Intermitt. access escalation Index0.30.40.9-0.20.2-0.2-0.3-0.6-0.20.90.0-0.4-0.6-0.9-0.7-0.8-0.2-0.1-0.8-0.8-1.0-0.8
Intermittent access day 1 total infusions0.30.41.1-0.71.0-1.0-0.9-0.8-1.00.6-0.70.60.60.80.2-0.30.30.70.10.10.30.3
Intermittent access day 15 total infusions0.81.22.3-1.31.5-1.5-1.4-1.2-1.50.8-1.21.11.21.10.90.00.50.71.11.10.90.6
Intermittent access terminal intake (last 3 days)0.60.81.7-0.91.3-1.3-1.0-0.8-1.00.5-0.80.91.01.00.80.40.20.51.21.20.80.5
Intermittent access total infusions0.70.81.9-1.11.4-1.4-1.2-1.2-1.41.0-1.00.80.80.80.5-0.10.30.70.70.70.40.2
Intermittent access day 1 locomotion1.62.03.0-1.41.7-1.7-1.5-1.3-1.31.1-1.61.71.71.61.70.31.31.61.31.31.21.1
Intermittent access day 15 total locomotion0.51.03.9-0.71.1-1.1-1.0-0.4-0.5-0.0-0.40.50.81.30.51.3-0.60.12.02.00.90.4
Intermittent access total locomotion1.41.72.7-1.21.5-1.5-1.3-1.1-1.61.1-1.51.51.51.61.30.01.21.71.01.01.01.0
Intermittent access standard deviation0.51.05.4-0.60.8-0.8-0.8-0.2-0.1-0.2-0.30.50.70.71.11.5-0.6-0.52.32.31.00.4
Left kidney weight6.027.967.88.1-8.28.28.27.95.8-6.75.8-4.7-4.3-3.7-2.82.5-1.2-1.9-2.6-2.6-0.90.7
Right kidney weight7.333.183.29.1-9.09.09.08.66.2-7.16.1-5.0-4.5-3.6-3.12.7-1.1-1.2-3.4-3.4-0.91.1
Cocaine induced anxiety2.13.15.5-2.32.3-2.3-2.3-2.3-1.82.3-2.31.91.70.91.3-1.51.61.50.00.00.70.6
Post-drug Anxiety0.30.30.7-0.10.4-0.4-0.4-0.20.40.50.2-0.3-0.4-0.9-0.6-0.9-0.0-0.4-0.9-0.9-0.7-0.7
Baseline Anxiety3.33.97.52.3-2.02.02.02.22.5-2.02.7-2.4-2.3-1.7-1.91.1-2.2-2.4-0.4-0.4-1.4-1.4
Tail length0.31.12.20.8-1.11.11.00.90.9-0.91.3-1.5-1.4-1.4-1.00.3-1.4-1.4-0.1-0.1-0.9-1.1
Length with tail2.08.515.43.6-3.93.93.93.73.2-3.33.5-3.3-3.2-3.1-2.31.6-2.4-2.4-0.9-0.9-1.7-1.4
Length without tail4.414.224.44.7-4.94.94.94.84.4-4.44.5-4.2-4.0-3.7-3.12.6-3.2-3.2-1.0-1.0-2.1-1.7
Times rat made contact with spout1.11.33.31.6-1.81.81.81.61.1-1.31.2-1.1-1.1-1.1-0.7-0.0-0.3-0.6-0.5-0.5-0.5-0.2
Lifetime Intake0.70.92.1-1.11.4-1.4-1.2-1.2-1.51.0-1.10.90.90.90.6-0.30.50.90.50.50.40.3
Liver weight, left8.313.731.95.6-5.35.35.35.44.6-4.64.4-3.6-3.2-2.6-2.12.9-2.0-1.8-0.9-0.9-0.9-0.0
Liver weight, right4.88.420.24.4-4.54.54.54.13.1-3.13.0-2.6-2.6-2.3-1.80.9-0.5-0.6-2.3-2.3-1.20.0
Locomotor activity0.00.10.2-0.50.2-0.2-0.2-0.1-0.30.3-0.30.1-0.0-0.3-0.1-0.40.00.0-0.1-0.1-0.3-0.4
Locomotor testing distance0.51.02.5-1.20.9-0.9-1.0-1.1-1.61.3-1.41.00.80.60.6-1.41.21.2-0.4-0.40.20.4
Locomotor testing rearing0.51.11.7-0.91.2-1.2-1.3-1.0-1.10.7-1.01.21.31.31.1-0.31.00.70.80.81.31.0
Locomotion in novel chamber0.60.72.60.8-0.80.80.80.6-0.2-0.5-0.30.40.41.00.3-0.41.31.6-1.0-1.00.71.3
Locomotion in novel chamber post-restriction1.11.74.8-0.20.2-0.2-0.20.1-0.7-0.4-1.21.71.82.11.80.61.71.90.70.72.02.2
Fecal boli incidents, locomotor time 10.30.41.90.1-0.40.40.50.41.4-0.80.6-0.2-0.2-0.70.20.7-0.3-1.40.60.6-0.1-0.4
Change in fecal boli incidents, locomotor task0.70.71.51.2-1.01.01.10.90.2-0.40.7-0.9-0.9-0.6-1.0-0.4-0.20.4-1.2-1.2-0.6-0.1
Time >=10cm from walls, locomotor time 10.10.10.2-0.20.2-0.2-0.2-0.30.00.40.0-0.1-0.2-0.4-0.3-0.5-0.1-0.3-0.4-0.4-0.5-0.5
Bouts of movement, locomotor time 10.50.51.40.5-0.50.50.40.30.5-0.20.8-1.1-1.0-0.9-1.1-0.2-1.2-0.8-0.3-0.3-0.8-0.9
Total resting periods, locomotor time 10.30.30.80.5-0.50.50.40.20.2-0.10.6-0.9-0.8-0.7-0.9-0.4-0.8-0.5-0.5-0.5-0.6-0.6
Rest time, locomotor task time 10.40.51.70.7-0.70.70.60.3-0.3-0.1-0.20.10.00.10.0-0.91.11.0-1.3-1.30.20.7
Distance moved, locomotor task time 10.40.52.3-0.50.6-0.6-0.7-0.1-0.0-0.0-0.20.50.70.90.71.2-0.3-0.11.51.50.80.4
Vertical activity count, locomotor time 10.20.51.2-0.60.7-0.7-0.7-0.3-0.30.2-0.50.80.81.00.80.80.10.41.11.10.70.5
Time >=10cm from walls, locomotor time 20.30.41.01.0-0.90.91.00.90.7-0.70.5-0.4-0.3-0.0-0.30.30.10.4-0.6-0.6-0.10.3
Bouts of movement, locomotor time 20.20.30.8-0.80.6-0.6-0.6-0.7-0.90.6-0.60.50.40.20.4-0.40.30.20.30.30.20.0
Total resting periods, locomotor time 20.20.41.1-0.90.8-0.8-0.8-0.9-1.00.8-0.70.60.50.30.4-0.40.30.30.30.30.30.1
Rest time, locomotor task time 20.30.41.0-0.70.8-0.8-0.9-1.0-0.80.9-0.70.50.40.30.3-0.60.40.4-0.0-0.00.20.1
Distance moved, locomotor task time 20.10.10.30.4-0.30.30.20.50.2-0.30.00.10.20.60.10.50.10.60.00.00.30.5
Vertical activity count, locomotor time 20.10.10.30.3-0.30.30.40.50.2-0.30.1-0.0-0.00.3-0.20.20.00.5-0.3-0.3-0.00.2
Light reinforcement 10.20.52.60.00.0-0.0-0.0-0.1-1.10.5-0.80.60.60.90.3-0.70.91.6-0.9-0.90.40.9
Light reinforcement 20.20.31.6-0.80.3-0.3-0.3-0.6-0.70.7-0.60.40.2-0.40.3-1.30.80.1-0.4-0.4-0.3-0.3
Bone: marrow area1.73.78.32.5-2.92.92.92.72.3-2.52.1-1.7-1.7-1.8-1.11.3-0.9-1.3-0.6-0.6-0.7-0.4
Bone: maximum diameter5.29.819.44.0-3.83.83.84.14.4-3.73.9-3.4-3.1-2.7-2.42.7-2.8-2.8-0.4-0.4-1.4-1.2
Bone: maximum force4.57.919.24.2-4.44.44.44.13.2-3.52.9-2.4-2.3-2.0-1.41.7-0.8-1.1-1.6-1.6-0.60.2
Bone: maximum moment4.98.620.34.3-4.54.54.54.23.3-3.53.1-2.7-2.5-2.3-1.71.6-1.0-1.2-1.8-1.8-0.9-0.0
Mean time between licks in bursts0.71.85.20.1-0.20.20.2-0.30.30.70.9-1.6-1.8-1.9-2.2-1.3-1.2-1.1-1.5-1.5-2.3-2.2
Mean num. licks in bursts0.40.72.40.7-0.80.80.80.6-0.2-0.4-0.40.60.60.50.7-0.31.51.2-0.8-0.80.81.4
Cd content in liver1.11.23.2-0.60.6-0.6-0.6-0.9-1.10.8-1.31.41.31.41.3-0.81.81.70.10.11.21.4
Co content in liver0.60.72.50.6-0.60.60.60.5-0.1-0.4-0.50.70.80.90.80.01.41.5-0.6-0.61.01.6
Cu content in liver0.10.10.8-0.10.2-0.2-0.2-0.2-0.10.1-0.20.30.30.30.60.90.10.20.40.40.40.4
Fe content in liver2.53.15.71.5-1.41.41.41.32.1-0.92.1-2.3-2.3-2.2-2.40.4-2.0-1.7-1.3-1.3-2.0-1.9
K content in liver0.20.20.6-0.30.6-0.6-0.6-0.5-0.30.4-0.20.10.20.10.30.5-0.2-0.10.80.80.20.0
Mg content in liver1.01.02.1-0.61.0-1.0-1.0-0.7-0.60.4-0.91.11.31.21.30.80.60.71.21.21.41.2
Mn content in liver0.20.20.80.5-0.30.30.30.3-0.3-0.4-0.00.20.40.70.40.30.40.50.10.10.80.9
Na content in liver0.60.72.20.7-0.40.40.40.90.8-1.30.7-0.10.10.20.51.5-0.6-0.81.31.30.90.6
Rb content in liver0.10.10.8-0.20.3-0.3-0.3-0.20.2-0.1-0.10.20.20.20.40.9-0.2-0.30.50.50.40.1
Se content in liver0.20.20.5-0.50.7-0.7-0.7-0.7-0.60.6-0.40.30.30.20.1-0.70.10.20.10.10.1-0.0
Sr content in liver7.06.19.1-2.62.6-2.6-2.6-2.5-2.82.0-2.93.03.03.02.8-1.12.52.51.51.52.32.1
Zn content in liver2.22.43.8-1.41.7-1.7-1.7-1.7-1.41.4-1.91.92.01.71.7-0.31.81.70.50.51.61.6
Bone: minimum diameter4.68.416.03.8-4.04.04.04.03.7-3.73.5-2.9-2.7-2.4-1.92.4-2.0-2.4-0.7-0.7-0.9-0.7
Time in familiar zone, hab. session 10.90.92.71.1-0.90.90.91.31.6-1.60.9-0.2-0.0-0.00.41.3-0.1-0.80.90.90.80.6
Time in novel zone, hab. session 11.41.43.9-1.81.4-1.4-1.5-1.9-1.42.0-0.90.2-0.1-0.4-0.5-1.4-0.4-0.0-0.4-0.4-1.3-1.5
Total zone transitions, hab. session 10.40.51.50.10.2-0.2-0.20.20.3-0.2-0.40.80.91.21.01.00.40.80.80.81.21.2
Total locomotion distance, hab. session 10.10.10.4-0.10.4-0.4-0.4-0.20.50.40.3-0.4-0.4-0.2-0.50.0-0.6-0.3-0.3-0.3-0.5-0.6
Locomotion velocity, hab. session 10.10.20.50.20.1-0.1-0.10.00.50.30.3-0.5-0.5-0.2-0.7-0.2-0.4-0.1-0.7-0.7-0.6-0.5
Time in familiar zone, hab. session 21.41.54.30.1-0.20.20.30.10.70.01.2-1.5-1.6-1.6-1.8-1.0-1.5-1.6-0.7-0.7-1.9-2.1
Time in novel zone, hab. session 20.60.61.9-0.1-0.00.0-0.10.0-0.2-0.1-0.71.01.10.81.40.61.10.70.40.41.21.3
Total zone transitions, hab. session 20.20.30.80.3-0.20.20.10.30.2-0.3-0.20.40.60.80.70.70.30.50.70.70.90.9
Total locomotion distance, hab. session 20.40.51.21.0-1.01.00.90.91.1-0.80.9-0.8-0.7-0.6-0.50.3-0.5-0.5-0.2-0.2-0.4-0.2
Locomotion velocity, hab. session 20.40.51.31.1-1.01.00.90.91.1-0.90.9-0.7-0.6-0.3-0.30.6-0.4-0.40.00.0-0.10.0
Novel to familiar place preference ratio0.70.72.10.2-0.50.50.50.20.20.10.6-1.0-1.2-1.5-1.1-0.3-0.6-0.9-1.0-1.0-1.4-1.3
Novelty place preference0.50.51.7-0.0-0.30.30.3-0.1-0.00.30.4-0.7-0.9-1.3-0.9-0.3-0.4-0.8-0.9-0.9-1.2-1.2
Time in novel zone, NPP test1.21.33.90.3-0.70.70.60.20.6-0.01.0-1.3-1.5-2.0-1.3-0.3-0.9-1.5-1.1-1.1-1.8-1.8
Total zone transitions, NPP test0.40.51.41.2-1.11.11.11.00.4-0.60.4-0.3-0.30.1-0.3-0.20.30.8-0.9-0.90.10.7
Total locomotion distance, NPP test0.30.41.11.0-0.90.90.90.70.5-0.30.4-0.5-0.5-0.3-0.5-0.20.10.5-1.0-1.0-0.30.2
Locomotion velocity, NPP test0.30.52.40.8-0.60.60.60.4-0.30.0-0.20.10.10.6-0.2-0.50.71.5-1.0-1.00.20.9
Intraocular pressure0.71.02.70.6-0.80.80.80.80.9-0.91.2-1.3-1.3-1.1-1.01.0-1.6-1.30.10.1-1.1-1.2
Delta distance traveled before/after self-admin0.20.20.6-0.60.8-0.8-0.8-0.7-0.40.5-0.40.20.30.50.1-0.0-0.20.20.40.40.1-0.1
Delta ambulatory time before/after self-admin0.10.10.3-0.30.5-0.5-0.5-0.5-0.20.3-0.1-0.10.00.4-0.20.3-0.60.10.50.5-0.0-0.2
Parametrial fat weight24.457.5119.810.9-10.410.410.410.59.1-9.29.4-8.2-7.4-5.6-5.84.6-5.4-4.7-2.2-2.2-2.8-1.5
Pavlov. Cond. lever latency0.60.72.2-1.11.5-1.5-1.5-1.3-0.91.2-0.50.20.30.5-0.2-0.2-0.6-0.00.60.6-0.1-0.5
Pavlov. Cond. magazine entry latency1.11.42.91.5-1.71.71.71.61.2-1.21.2-1.2-1.2-1.2-1.10.3-0.6-0.6-0.9-0.9-0.8-0.5
Pavlov. Cond. change in total contacts3.03.26.12.1-2.52.52.52.22.2-2.02.0-1.8-1.9-2.1-1.10.7-0.8-1.7-0.9-0.9-1.2-0.9
Pavlov. Cond. index score1.21.63.71.7-1.91.91.91.81.4-1.51.3-1.1-1.1-1.2-0.70.4-0.3-0.7-0.8-0.8-0.6-0.2
Pavlov. Cond. latency score1.01.33.21.5-1.81.81.81.71.3-1.41.1-0.9-1.0-1.0-0.50.3-0.1-0.6-0.7-0.7-0.5-0.2
Pavlov. Cond. lever contacts1.01.12.81.4-1.71.71.71.71.5-1.71.0-0.6-0.6-0.70.11.00.0-0.6-0.1-0.10.00.2
Pavlov. Cond. magazine entry number1.31.63.4-1.61.8-1.8-1.9-1.7-1.31.4-1.31.21.31.30.9-0.50.60.70.90.90.80.4
Pavlov. Cond. intertrial magazine entries2.12.55.82.3-2.42.42.42.11.3-1.41.5-1.4-1.5-1.2-1.3-0.2-0.00.1-1.9-1.9-0.80.0
Pavlov. Cond. lever-magazine prob. diff.1.62.04.51.8-2.12.12.12.01.6-1.61.5-1.3-1.4-1.4-0.90.4-0.4-0.8-1.0-1.0-0.8-0.5
Pavlov. Cond. response bias0.81.02.81.4-1.61.61.71.61.1-1.30.9-0.7-0.8-0.9-0.40.6-0.0-0.4-0.6-0.6-0.30.0
Pavlov. Cond. lever latency1.72.44.2-1.61.6-1.6-1.6-1.5-1.61.0-1.92.12.01.71.9-1.01.91.20.60.61.51.4
Pavlov. Cond. magazine entry latency0.40.51.60.2-0.30.30.30.50.9-0.50.9-0.8-0.8-0.7-0.70.1-1.3-1.10.60.6-0.7-1.0
Pavlov. Cond. change in total contacts0.60.92.10.8-0.60.60.60.61.0-0.41.2-1.3-1.3-1.1-1.20.7-1.5-1.0-0.1-0.1-1.1-1.1
Pavlov. Cond. index score1.01.42.81.1-1.01.01.01.11.3-0.71.5-1.6-1.5-1.3-1.50.6-1.7-1.1-0.2-0.2-1.2-1.2
Pavlov. Cond. latency score0.91.22.51.1-0.90.90.91.01.2-0.61.4-1.5-1.5-1.1-1.50.6-1.6-0.9-0.2-0.2-1.1-1.1
Pavlov. Cond. lever contacts1.21.62.61.5-1.41.41.41.41.5-0.91.5-1.6-1.6-1.3-1.41.0-1.5-0.9-0.4-0.4-1.1-0.9
Pavlov. Cond. magazine entry number0.30.30.7-0.40.4-0.4-0.4-0.6-0.90.6-0.70.60.50.40.4-0.60.90.7-0.6-0.60.40.5
Pavlov. Cond. intertrial magazine entries0.91.44.62.1-1.91.91.91.70.7-1.51.0-0.8-0.6-0.2-0.50.9-0.10.4-0.8-0.80.41.0
Pavlov. Cond. lever-magazine prob. diff.0.60.82.10.8-0.70.70.70.81.1-0.61.2-1.2-1.2-1.0-1.10.7-1.4-0.90.10.1-0.9-1.0
Pavlov. Cond. response bias1.72.34.01.3-1.41.41.41.41.6-0.91.8-2.0-2.0-1.9-1.90.6-1.9-1.5-0.5-0.5-1.7-1.7
Time in closed arm before self-admin0.10.20.5-0.30.7-0.7-0.7-0.6-0.20.5-0.20.30.30.50.1-0.00.10.10.00.00.20.1
Time in closed arm after self-admin1.01.02.5-0.80.7-0.7-0.7-1.0-1.60.9-1.41.21.11.00.7-1.01.51.4-0.6-0.60.60.9
Time in open arm before self-admin1.01.12.8-1.71.2-1.2-1.2-1.3-1.31.0-1.41.11.10.61.1-0.40.60.50.90.90.50.1
Time in open arm after self-admin1.11.25.1-0.10.1-0.1-0.10.11.2-0.21.1-1.2-1.2-1.5-1.0-0.1-1.6-2.30.20.2-1.3-1.9
Bone: periosteal estimation5.712.125.44.9-5.05.05.05.04.4-4.43.9-3.3-3.1-2.8-2.22.4-1.9-2.1-1.3-1.3-1.0-0.4
Bone: periosteal perimeter6.511.222.74.7-4.54.54.54.84.7-4.74.0-3.1-2.6-2.2-1.73.5-2.4-2.60.00.0-0.3-0.1
Bone: post-yield work2.13.04.71.9-2.22.22.21.71.6-1.01.7-1.9-2.1-2.1-2.1-0.1-1.0-0.9-1.9-1.9-1.8-1.2
Progressive ratio test 1 active lever presses1.21.52.7-1.51.7-1.7-1.6-1.4-1.41.1-1.41.41.41.31.1-0.10.81.00.80.80.90.7
Progressive ratio test 1 breakpoint1.11.32.3-1.31.5-1.5-1.4-1.2-1.31.0-1.31.31.31.31.0-0.10.81.00.70.70.90.7
Progressive ratio test 1 inactive lever presses0.10.10.5-0.30.7-0.7-0.4-0.3-0.10.1-0.0-0.1-0.00.4-0.20.3-0.6-0.00.50.5-0.1-0.3
Progressive ratio test 2 active lever presses0.60.61.9-0.50.6-0.6-0.5-0.4-0.90.2-0.60.70.91.00.90.90.20.71.41.41.00.8
Progressive ratio test 2 breakpoint0.50.61.8-0.40.6-0.6-0.5-0.3-0.90.2-0.60.60.70.90.80.90.10.61.41.40.80.7
Progressive ratio test 2 inactive lever presses0.10.10.40.00.3-0.3-0.1-0.2-0.50.40.1-0.3-0.3-0.1-0.60.1-0.60.20.00.0-0.4-0.3
Incentive Sensitization - Responses0.30.41.70.4-0.30.30.40.50.0-0.50.3-0.10.00.20.31.3-0.5-0.21.31.30.50.4
Incentive Sensitization - Breakpoint0.30.31.70.3-0.30.30.30.4-0.1-0.40.2-0.2-0.10.10.31.3-0.6-0.21.31.30.30.2
Sum of active levers in priming session hrs 5-60.40.41.20.8-0.60.60.60.70.1-0.60.7-0.9-0.7-0.1-0.90.2-1.1-0.2-0.0-0.0-0.3-0.3
Progressive ratio2.74.38.4-2.72.9-2.9-2.9-2.6-2.22.1-2.32.12.12.21.7-0.10.71.31.71.71.30.8
Food seeking constrained by brief footshock3.64.411.0-3.03.3-3.3-3.3-2.9-1.92.3-2.11.91.91.91.3-0.10.20.61.71.70.90.1
Seeking ratio, punishment vs. effort0.10.10.30.2-0.10.10.10.10.20.10.1-0.2-0.2-0.4-0.2-0.30.2-0.1-0.6-0.6-0.4-0.2
Retroperitoneal fat weight27.9118.9244.015.6-15.015.015.015.013.5-13.013.4-11.5-10.5-8.5-8.46.9-7.5-6.8-3.6-3.6-4.2-2.1
Reaction time number correct0.20.41.70.5-0.60.60.60.61.0-0.70.7-0.6-0.5-0.6-0.11.3-0.8-1.00.40.4-0.2-0.4
Reaction time mean minus median0.51.22.7-0.61.0-1.0-1.0-0.7-0.20.2-0.81.21.31.31.51.30.40.51.61.61.51.2
Reaction time mean minus median AUC1.22.96.5-0.91.2-1.2-1.2-0.8-0.40.0-1.32.02.32.22.51.71.00.92.42.42.52.1
Reaction time num false alarms0.91.33.91.3-2.02.01.81.50.5-0.90.4-0.4-0.6-0.8-0.4-0.60.90.6-1.6-1.6-0.40.3
Reaction time num false alarms AUC0.81.34.41.4-2.12.11.91.70.8-1.30.5-0.3-0.5-0.7-0.0-0.10.90.3-1.1-1.1-0.10.5
Reaction time trials correct on left0.20.41.70.5-0.60.60.60.61.0-0.70.7-0.6-0.5-0.6-0.11.3-0.8-1.00.40.4-0.2-0.4
Reaction time trials on left0.20.51.80.5-0.50.50.60.51.0-0.70.8-0.6-0.6-0.6-0.21.3-0.8-1.00.40.4-0.2-0.5
Reaction time mean2.54.07.1-2.42.7-2.7-2.6-2.3-1.41.5-2.02.32.32.22.10.90.80.92.22.21.81.1
Reaction time mean AUC3.14.98.5-2.62.9-2.9-2.9-2.6-1.71.6-2.32.52.62.52.30.81.01.22.32.32.01.3
Median of all reaction times3.14.48.2-2.62.9-2.9-2.8-2.5-1.61.7-2.22.42.42.32.10.60.91.02.02.01.71.0
Reaction time omissions0.20.31.0-0.40.7-0.7-0.6-0.60.00.40.3-0.3-0.20.0-0.60.4-1.0-0.40.30.3-0.4-0.7
Reaction time false alarm rate0.81.13.41.2-1.91.91.71.50.4-1.00.3-0.3-0.4-0.6-0.2-0.70.90.6-1.3-1.3-0.20.5
Reaction time premature initiation rate0.20.31.4-0.10.4-0.4-0.5-0.10.20.2-0.50.70.81.20.50.30.41.00.10.10.80.9
Reaction time premature initiations0.10.20.90.3-0.00.0-0.10.30.7-0.20.00.30.40.80.40.9-0.10.40.30.30.70.7
Std. dev. reaction times0.50.92.6-0.60.8-0.8-0.8-0.60.00.1-0.61.01.11.01.31.30.20.21.61.61.20.9
Reaction time trials completed0.20.51.80.5-0.50.50.60.51.0-0.70.8-0.6-0.6-0.6-0.21.3-0.8-1.00.40.4-0.2-0.5
Reaction time trials AUC0.30.61.70.8-0.90.90.90.81.2-0.90.9-0.8-0.7-0.8-0.21.3-0.8-1.10.20.2-0.3-0.5
Run reversals in cocaine runway, females0.50.51.6-0.81.2-1.2-1.3-0.80.20.7-0.20.30.30.50.10.5-0.7-0.31.01.00.1-0.3
Run reversals in cocaine runway, males1.51.53.4-1.01.1-1.1-1.1-1.1-1.71.0-1.51.51.51.61.0-0.31.21.80.30.31.21.4
Latency to leave start box in cocaine runway0.91.12.9-1.41.4-1.4-1.5-1.3-0.50.6-0.20.20.3-0.10.50.3-0.7-1.51.71.70.1-0.8
Latency to leave start box in cocaine runway, F0.30.31.5-0.40.4-0.4-0.5-0.4-0.20.20.3-0.4-0.3-0.4-0.30.0-0.8-1.20.70.7-0.3-0.8
Latency to leave start box in cocaine runway, M0.90.83.1-1.01.0-1.0-1.0-0.8-0.00.0-0.40.60.80.51.20.8-0.0-0.81.81.80.80.1
Std. dev. time between licks in bursts0.70.92.5-0.80.6-0.6-0.6-1.0-0.51.4-0.2-0.3-0.6-0.9-0.9-1.6-0.0-0.0-1.4-1.4-1.5-1.3
Total sessions with >9 infusions1.51.83.0-1.31.6-1.6-1.5-1.5-1.61.3-1.51.41.41.71.10.20.81.70.80.81.00.9
Short access day 1 total inactive lever presses0.50.72.0-0.30.9-0.9-0.7-0.9-0.71.30.0-0.7-0.8-0.4-1.1-0.9-0.70.3-0.7-0.7-1.4-1.2
Short access day 10 total inactive lever presses0.81.85.02.2-2.22.22.22.01.0-1.71.3-1.2-1.1-0.5-0.80.7-0.50.2-0.8-0.8-0.20.4
Short access day 1 total infusions0.40.61.8-0.81.0-1.0-0.9-0.8-1.31.0-0.90.60.60.70.2-0.50.51.2-0.1-0.10.10.2
Short access day 10 total infusions1.62.13.9-2.01.9-1.9-1.8-1.8-2.01.5-1.81.61.51.11.2-1.21.41.00.10.10.60.4
Short access total infusions1.21.53.4-1.51.6-1.6-1.5-1.5-1.81.5-1.51.31.21.10.8-0.91.11.4-0.1-0.10.50.5
Short access day 1 locomotion0.70.81.9-0.60.9-0.9-0.8-0.6-0.80.4-0.80.91.01.40.90.90.31.11.21.21.00.9
Short access day 10 total locomotion0.61.12.0-1.01.1-1.1-1.1-0.8-0.70.6-1.21.41.41.31.40.11.01.00.90.91.11.0
Short access total locomotion2.83.35.1-1.82.0-2.0-1.9-1.6-1.71.4-2.22.32.22.32.10.11.82.21.21.21.61.6
One hour access (0.3 mA shock)0.50.61.4-0.81.2-1.2-1.0-1.0-1.00.7-0.2-0.2-0.10.4-0.30.0-1.0-0.30.80.8-0.4-0.8
Compulsive drug intake1.11.32.41.2-1.21.21.31.00.7-0.91.4-1.6-1.5-1.0-1.50.0-1.3-1.0-0.9-0.9-1.3-1.1
One hour access (shock baseline)1.11.74.0-1.62.0-2.0-1.9-1.8-1.91.6-1.41.11.01.10.7-0.60.50.90.70.70.40.2
Social response proportion1.01.22.61.3-1.51.51.61.11.2-0.50.7-0.8-1.0-1.2-0.90.00.20.3-1.6-1.6-1.0-0.3
Social responses2.43.17.82.4-2.12.12.02.12.8-1.82.2-2.0-1.9-1.5-1.71.4-1.5-1.2-0.6-0.6-1.0-0.8
Social time0.10.20.90.3-0.30.30.20.20.7-0.60.4-0.2-0.1-0.10.10.9-0.2-0.70.50.50.1-0.1
Soleus weight1.44.110.63.3-2.92.93.03.22.3-3.21.7-0.8-0.40.20.32.6-0.10.10.20.21.41.9
Bone: stiffness1.93.17.62.6-2.82.82.82.52.1-2.01.8-1.5-1.5-1.4-0.80.8-0.3-0.6-1.2-1.2-0.50.1
Tibialis anterior weight0.10.51.10.9-0.80.80.80.70.8-0.40.8-0.8-0.8-0.9-0.41.0-0.7-0.5-0.5-0.5-0.5-0.3
Time to tail flick, vehicle, before self-admin0.20.20.90.3-0.20.20.20.20.60.20.4-0.5-0.6-0.9-0.50.0-0.4-0.1-0.1-0.1-0.6-0.5
Time to tail flick, vehicle, after self-admin0.00.10.20.20.2-0.2-0.2-0.00.5-0.30.2-0.00.10.30.00.4-0.3-0.20.30.30.30.2
Time to tail flick, test, before self-admin2.93.05.7-1.71.5-1.5-1.5-1.3-1.71.0-2.12.32.32.12.4-0.12.11.81.11.11.81.7
Time to tail flick, test, after self-admin0.90.92.40.20.3-0.3-0.3-0.40.60.80.7-1.1-1.2-1.2-1.5-0.8-0.9-0.7-1.2-1.2-1.6-1.4
Delta time to tail flick, vehicle, before/after SA0.60.62.00.6-0.20.20.20.71.1-1.40.8-0.30.10.70.11.4-0.8-0.91.11.10.80.4
Delta time to tail flick, test, before/after SA3.23.37.11.5-1.11.11.10.91.7-0.21.9-2.3-2.4-2.5-2.7-1.0-1.6-1.4-2.2-2.2-2.4-2.0
Tibia length0.30.82.01.2-1.41.41.41.41.1-1.20.9-0.7-0.7-0.7-0.10.9-0.2-0.5-0.3-0.3-0.2-0.0
Ambulatory time before self-admin2.13.26.0-1.71.6-1.6-1.6-1.5-2.41.2-2.32.32.22.21.8-0.92.22.20.20.21.71.8
Ambulatory time after self-admin3.23.87.8-2.22.4-2.4-2.4-2.2-2.81.7-2.42.12.22.51.5-0.81.42.00.70.71.41.2
Bone: tissue strength0.20.20.5-0.60.4-0.4-0.4-0.5-0.10.3-0.0-0.2-0.2-0.2-0.10.0-0.6-0.60.50.5-0.4-0.7
Total heroin consumption3.13.610.12.5-2.12.12.12.92.5-3.22.3-1.5-1.00.0-0.52.6-1.7-1.61.21.20.60.4
Bone: trabecular number2.43.97.22.5-2.72.72.72.41.7-1.92.3-2.3-2.3-2.1-1.80.8-1.4-1.3-1.2-1.2-1.6-1.1
Bone: trabecular spacing1.82.46.3-2.42.2-2.2-2.2-2.5-2.12.4-1.51.00.70.40.1-2.00.40.4-0.1-0.1-0.5-0.9
Bone: trabecular thickness7.79.720.14.5-4.24.24.24.43.9-4.23.7-3.1-2.7-1.9-2.03.1-2.3-2.0-0.5-0.5-0.6-0.2
Bone: trabecular tissue density1.01.44.0-1.61.3-1.3-1.3-1.5-1.62.0-1.50.80.60.30.1-1.70.91.1-0.9-0.9-0.5-0.3
Water consumed over 24 hours0.10.20.40.5-0.70.70.70.4-0.1-0.50.10.10.10.00.4-0.20.60.3-0.0-0.00.40.6
Number of responses in last shaping day0.90.91.4-1.01.1-1.1-1.0-1.1-1.10.8-1.21.11.11.00.90.30.61.20.90.90.70.7