Pla2g4b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative TSS XM_039104946.1 0.04 0.03 8.9e-03 0.01 0 0.01 0.01 3.7e-02 9.5e-02 1.7e-02 6.5e-02
2 Liver isoform ratio XM_039104944.1 0.05 0.03 1.8e-03 0.03 0.01 0.01 0.01 4.0e-04 1.0e-02 3.2e-02 1.0e-02
3 NAcc mRNA stability Pla2g4b 0.02 0.01 5.9e-03 0.01 0.02 0 0.01 4.5e-02 2.7e-03 1.1e-01 3.3e-02
4 PL intron excision ratio chr3_107004412_107006623 0.04 0.02 1.6e-05 0.03 0.04 0.04 0.04 4.5e-04 3.5e-05 1.4e-05 4.2e-05
5 BLA isoform ratio XM_006234775.3 0.07 0.04 4.9e-04 0.02 0.04 0.02 0.01 2.0e-02 2.8e-03 4.6e-02 5.2e-02
6 NAcc intron excision ratio chr3_107004412_107006623 0.02 0.01 1.6e-03 0.02 0.02 0.02 0.02 1.8e-03 8.2e-04 2.0e-03 5.1e-03
7 PL intron excision ratio chr3_107005335_107006623 0.03 0.02 5.9e-04 0.02 0.03 0.02 0.02 1.1e-03 3.8e-04 1.5e-03 1.8e-03
8 Brain isoform ratio XM_039104944.1 0.27 0.09 5.6e-16 0.19 0.18 0.19 0.19 1.9e-17 5.7e-17 1.4e-17 1.2e-17
9 PL isoform ratio XM_006234775.3 0.06 0.04 5.3e-07 0.03 0.06 0.07 0.06 2.1e-04 7.3e-07 9.0e-08 9.0e-07
10 NAcc gene expression Pla2g4b 0.04 0.02 4.5e-05 0.03 0.02 0.02 0.02 3.6e-04 1.2e-03 3.8e-03 1.7e-03
11 Brain isoform ratio XM_006234775.3 0.07 0.04 3.7e-08 0.09 0.08 0.08 0.09 1.6e-08 1.0e-07 4.2e-08 2.4e-08
12 Brain mRNA stability Pla2g4b 0.11 0.06 1.3e-11 0.13 0.12 0.13 0.12 2.6e-12 3.3e-11 7.1e-12 5.6e-11
13 Brain gene expression Pla2g4b 0.16 0.07 0.0e+00 0.23 0.21 0.22 0.2 4.9e-21 2.3e-19 2.9e-20 5.1e-18
14 Brain intron excision ratio chr3_107005335_107006623 0.06 0.03 5.1e-06 0.07 0.06 0.05 0.06 6.5e-07 6.2e-06 1.4e-05 6.0e-06
15 Brain alternative TSS NM_001107764.2 0.06 0.03 1.3e-07 0.08 0.09 0.09 0.09 5.7e-08 1.0e-08 2.2e-08 1.2e-08
16 IL gene expression Pla2g4b 0.46 0.17 4.9e-08 0.28 0.29 0.31 0.32 2.4e-07 1.2e-07 2.8e-08 2.1e-08
17 Brain alternative TSS NM_001107764.2 0.07 0.04 1.5e-08 0.1 0.1 0.1 0.11 1.8e-09 8.8e-10 1.7e-09 4.8e-10
18 NAcc intron excision ratio chr3_107005335_107006623 0.02 0.01 2.3e-03 0.02 0.02 0.01 0.02 1.8e-03 3.0e-03 1.2e-02 3.0e-03
19 BLA mRNA stability Pla2g4b 0.16 0.08 9.0e-07 0.1 0.07 0.09 0.09 6.0e-06 8.9e-05 2.2e-05 1.4e-05
20 OFC gene expression Pla2g4b 0.19 0.11 4.2e-03 0.1 0.09 0.07 0.07 2.1e-03 4.9e-03 8.1e-03 9.5e-03
21 Brain isoform ratio NM_001107764.2 0.08 0.04 6.7e-07 0.03 0.06 0.06 0.05 1.2e-03 1.1e-06 3.1e-06 1.8e-05
22 Liver alternative TSS XM_039104945.1 0.03 0.02 8.1e-04 0 0 0.01 0 1.1e-01 8.7e-02 4.7e-02 8.4e-02
23 PL gene expression Pla2g4b 0.1 0.05 7.3e-09 0.06 0.08 0.08 0.08 1.9e-07 4.4e-09 5.2e-09 5.4e-09
24 BLA gene expression Pla2g4b 0.22 0.1 3.1e-08 0.04 0.11 0.1 0.07 2.6e-03 2.5e-06 5.0e-06 9.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.81.42.8-0.50.61.51.31.4-1.51.4-1.7-0.9-1.2-1.2-1.2-1.2-1.3-1.31.5-1.4-1.4-1.4-0.5-0.6-0.50.70.8
Area under the delay curve3.03.27.3-0.10.71.50.82.3-1.81.8-1.4-2.1-1.8-1.8-1.8-1.8-1.5-2.11.7-1.5-1.2-1.2-2.0-1.8-2.42.72.6
BMI with tail3.812.219.51.1-0.74.24.43.3-4.34.3-3.5-4.2-3.9-4.0-4.0-3.9-4.0-4.14.2-4.1-4.0-4.0-0.1-3.1-0.11.52.2
BMI without tail4.18.515.3-0.41.03.93.73.4-3.63.5-3.2-2.9-3.2-3.4-3.4-3.4-3.6-3.33.3-3.1-3.0-3.0-1.1-1.9-0.81.41.8
Body weight4.016.728.71.8-1.25.15.43.7-5.05.0-3.7-4.3-4.7-4.7-4.7-4.7-4.7-4.74.8-4.8-4.7-4.7-0.1-3.70.11.42.4
Weight adjusted by age0.91.02.61.6-0.81.00.80.8-0.91.00.1-1.6-1.3-1.2-1.2-1.3-0.9-1.10.7-0.7-0.7-0.7-0.6-1.4-0.50.81.0
Bone surface0.50.92.50.2-0.11.21.50.8-1.31.2-1.6-0.9-0.9-0.9-0.9-0.9-1.0-1.01.2-1.1-1.1-1.10.6-0.40.5-0.20.1
Bone volume0.61.12.6-0.00.11.31.60.9-1.41.3-1.6-0.9-1.1-1.1-1.1-1.1-1.2-1.11.1-1.1-1.1-1.10.7-0.50.4-0.00.2
Breakpoint value in progressive ratio session0.20.31.7-0.90.70.10.3-0.0-0.20.1-1.3-0.40.20.30.30.10.50.10.20.20.50.51.00.70.6-0.5-0.6
Number of licking bursts0.40.41.5-1.11.2-0.3-0.2-0.00.2-0.3-1.20.30.60.60.60.60.60.4-0.30.60.70.70.61.10.3-0.4-0.6
Context. condit. distance diff. score0.91.03.6-0.20.11.71.90.9-1.31.2-1.0-0.5-1.3-1.2-1.2-1.2-1.2-0.90.7-0.8-0.9-0.90.5-0.20.9-0.8-0.4
Locomotion velocity, session 11.81.95.7-0.90.9-1.8-2.4-0.81.7-1.71.51.81.41.41.41.41.41.4-1.31.31.21.2-1.40.7-1.30.80.2
Locomotion distance, session 10.81.12.9-0.70.9-1.1-1.7-0.31.2-1.21.31.50.90.90.90.90.91.0-1.10.90.80.8-1.50.6-1.30.60.2
Locomotion velocity, session 22.12.45.2-0.71.51.30.52.1-1.41.3-1.0-0.6-1.5-1.5-1.5-1.4-1.5-1.51.3-1.5-1.6-1.6-2.2-1.1-2.32.32.1
Locomotion distance, session 20.30.41.3-0.51.1-0.4-0.90.10.6-0.60.31.10.50.50.50.60.50.6-0.60.40.20.2-1.10.8-0.90.3-0.0
Locomotion velocity, session 30.40.51.6-1.01.20.2-0.20.9-0.40.4-0.70.6-0.5-0.6-0.6-0.5-0.6-0.60.2-0.3-0.5-0.5-0.7-0.3-1.21.31.1
Locomotion distance, session 30.40.52.7-1.51.4-0.1-0.10.10.2-0.3-0.41.60.10.10.10.20.10.4-1.00.70.30.30.61.00.2-0.5-0.5
Stereotopy head waving bouts, day 33.03.65.81.0-0.71.91.81.8-2.02.1-0.6-1.9-2.3-2.2-2.2-2.2-2.2-2.32.0-2.1-2.1-2.1-0.8-2.4-0.91.62.0
Stereotopy head waving duration, day 35.16.18.80.4-0.22.41.92.6-2.72.7-1.4-2.4-2.8-2.7-2.7-2.7-2.7-2.93.0-2.9-2.7-2.7-1.7-2.9-1.82.62.9
Locomotion velocity, session 70.20.20.5-0.20.70.60.50.6-0.30.30.20.7-0.6-0.7-0.7-0.7-0.7-0.3-0.50.1-0.3-0.3-0.5-0.0-0.3-0.00.2
Locomotion distance, session 70.30.41.4-0.30.4-0.00.1-0.40.4-0.50.31.00.40.40.40.40.40.6-1.00.70.40.40.41.00.8-1.2-1.1
Stereotopy head waving bouts, day 70.10.21.01.0-1.0-0.10.2-0.3-0.10.20.2-0.7-0.2-0.2-0.2-0.1-0.2-0.20.2-0.10.00.00.6-0.60.4-0.10.1
Stereotopy head waving duration, day 70.10.21.01.0-1.0-0.5-0.1-0.50.1-0.10.4-0.50.10.00.00.10.0-0.0-0.00.10.20.20.7-0.50.40.00.1
Locomotion velocity, session 82.73.35.7-0.00.92.21.52.4-2.01.9-1.0-0.9-2.3-2.2-2.2-2.2-2.2-2.01.5-1.7-1.9-1.9-1.8-1.5-1.61.71.9
Locomotion distance, session 80.30.41.5-0.50.81.21.00.9-0.70.6-0.40.3-0.8-0.7-0.7-0.7-0.7-0.40.1-0.4-0.7-0.7-0.40.20.0-0.4-0.2
Degree of sensitization distance0.80.82.31.4-1.5-0.6-0.2-1.30.8-0.71.0-0.20.80.90.90.80.90.8-0.40.40.70.70.80.31.2-1.2-1.2
Degree of sensitization stereotypy0.70.81.60.8-0.9-1.0-0.4-1.20.9-0.80.80.20.80.70.70.80.70.8-0.91.01.01.01.30.41.1-1.0-0.9
Conditioned locomotion1.72.04.10.5-0.02.02.01.5-1.81.8-1.3-1.8-1.7-1.7-1.7-1.7-1.7-1.61.5-1.4-1.3-1.3-0.3-1.0-0.10.40.7
Cocaine response after cond. corrected1.01.25.8-2.42.2-0.8-1.10.00.6-0.8-1.21.51.01.01.01.00.90.8-0.61.01.01.00.01.5-0.50.2-0.3
Cocaine response after cond. not corrected1.31.46.9-2.62.4-0.9-1.40.20.7-0.9-1.11.51.11.11.11.11.00.8-0.50.91.01.0-0.61.5-1.00.5-0.0
Cocaine response before conditioning0.20.21.50.3-0.1-0.2-0.60.10.3-0.21.00.2-0.0-0.0-0.0-0.0-0.00.1-0.1-0.1-0.2-0.2-1.2-0.4-0.90.70.6
Saline control response1.62.14.42.0-2.11.41.80.5-1.31.50.4-1.3-1.6-1.6-1.6-1.6-1.6-1.51.4-1.7-1.8-1.80.2-2.10.40.20.8
Bone: connectivity density0.40.61.30.8-0.60.80.90.5-0.80.9-0.5-1.1-0.7-0.7-0.7-0.7-0.8-0.81.1-1.1-1.1-1.1-0.2-0.8-0.10.40.5
Bone: cortical apparent density2.12.84.90.2-0.7-1.7-0.9-2.11.6-1.60.70.91.81.81.81.81.81.7-1.61.71.81.82.21.62.0-2.1-2.1
Bone: cortical area1.42.23.70.4-0.21.81.91.4-1.81.8-1.4-1.4-1.8-1.8-1.8-1.8-1.8-1.81.6-1.5-1.5-1.50.1-1.4-0.10.61.0
Bone: cortical porosity1.11.25.7-2.02.40.1-1.01.2-0.0-0.1-0.40.9-0.10.10.1-0.10.1-0.10.00.20.20.2-2.30.4-2.21.71.2
Bone: cortical porosity1.01.14.2-1.51.70.7-0.31.5-0.60.5-0.50.4-0.8-0.7-0.7-0.8-0.7-0.70.6-0.5-0.6-0.6-2.0-0.4-2.01.71.5
Bone: cortical thickness1.22.03.20.30.11.71.61.6-1.71.7-1.3-1.1-1.7-1.7-1.7-1.7-1.8-1.71.4-1.5-1.6-1.6-0.5-1.3-0.50.91.2
Bone: cortical thickness0.40.43.8-1.51.30.20.30.3-0.40.2-2.00.30.20.30.30.20.2-0.00.4-0.00.10.10.80.90.4-0.3-0.4
Bone: cortical tissue density2.02.64.60.2-0.7-1.7-0.9-2.01.5-1.50.60.91.81.81.81.81.81.7-1.51.71.81.82.21.51.9-2.0-2.0
Condit. Reinf. active minus inactive responses2.02.36.72.6-2.4-1.5-0.5-2.21.5-1.32.10.21.21.11.11.11.21.3-1.51.21.11.11.70.21.8-1.8-1.5
Condit. Reinf. active-inactive response ratio0.50.53.71.9-1.6-0.00.6-0.6-0.00.10.6-0.9-0.2-0.2-0.2-0.3-0.2-0.1-0.20.00.10.11.1-0.61.0-0.7-0.3
Condit. Reinf. active responses4.15.010.53.0-3.0-2.3-1.2-3.22.4-2.23.01.02.12.02.02.02.02.2-2.41.81.61.62.20.82.5-2.6-2.4
Condit. Reinf. inactive responses3.34.07.11.2-1.6-2.1-1.4-2.72.3-2.22.41.92.12.12.12.02.02.3-2.31.81.51.51.61.41.9-2.3-2.3
Incentive salience index mean3.03.77.82.7-2.5-2.2-1.3-2.82.2-2.02.80.51.81.81.81.71.81.9-2.01.61.61.61.60.61.7-1.8-1.8
Condit. Reinf. lever presses1.92.56.82.6-2.2-1.9-1.3-2.31.9-1.72.60.31.61.61.61.51.51.6-1.61.11.01.00.80.41.1-1.2-1.3
Condit. Reinf. active minus inactive responses0.81.04.41.9-2.10.41.3-0.8-0.30.40.2-1.2-0.1-0.1-0.1-0.1-0.2-0.10.5-0.6-0.6-0.61.7-0.32.0-1.5-1.1
Condit. Reinf. active-inactive response ratio0.60.72.71.5-1.60.31.0-0.7-0.20.30.0-1.2-0.00.00.0-0.0-0.1-0.00.3-0.3-0.3-0.31.4-0.11.6-1.3-1.0
Condit. Reinf. active responses1.01.46.92.4-2.60.61.6-0.9-0.40.60.3-1.5-0.4-0.3-0.3-0.3-0.4-0.30.6-0.7-0.6-0.62.0-0.62.2-1.7-1.1
Condit. Reinf. inactive responses0.70.95.42.1-2.30.31.1-0.6-0.40.60.5-1.3-0.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.3-0.31.4-1.11.4-0.8-0.3
Condit. Reinf. lever presses0.81.07.12.5-2.70.00.8-0.8-0.30.50.8-1.5-0.4-0.4-0.4-0.4-0.4-0.40.6-0.7-0.5-0.51.3-1.31.2-0.5-0.1
Condit. Reinf. lever reinforcers received1.11.58.62.7-2.90.31.4-1.1-0.20.40.7-1.4-0.2-0.2-0.2-0.2-0.2-0.20.4-0.6-0.5-0.51.9-0.72.2-1.6-1.1
Conditioned reinforcement - actives0.20.21.10.7-0.8-0.1-0.2-0.00.10.01.0-0.3-0.2-0.1-0.1-0.1-0.2-0.20.2-0.3-0.3-0.3-0.6-0.8-0.60.50.5
Conditioned reinforcement - inactives0.10.10.5-0.70.30.20.2-0.00.0-0.0-0.00.6-0.10.10.10.20.10.2-0.20.20.00.00.40.50.5-0.7-0.6
Conditioned locomotion0.60.73.31.5-1.1-0.3-0.60.00.2-0.01.8-0.3-0.4-0.3-0.3-0.2-0.4-0.30.1-0.4-0.5-0.5-1.5-1.4-1.01.21.2
Patch foraging indifference point 0 sec2.33.810.42.4-2.21.21.41.0-1.61.80.5-1.2-2.3-2.2-2.2-2.0-2.4-2.11.8-2.3-2.4-2.4-0.3-3.2-0.81.72.3
Patch foraging indifference point AUC2.73.14.7-0.6-0.1-2.1-1.9-2.02.1-2.11.91.72.21.91.91.82.02.0-2.02.12.12.10.71.50.8-1.3-1.5
Delay disc. indifference point, 0s delay0.50.62.11.4-1.0-0.3-0.50.2-0.00.20.8-0.9-0.2-0.5-0.5-0.4-0.2-0.50.2-0.3-0.2-0.2-0.9-1.3-1.21.41.4
Delay disc. indifference point, 16s delay1.11.14.6-0.61.10.4-0.11.5-0.90.8-1.0-0.9-0.8-0.8-0.8-0.8-0.5-1.00.7-0.4-0.2-0.2-1.4-0.8-2.02.11.9
Delay disc. indifference point, 2s delay0.40.41.91.4-0.70.70.80.3-0.60.6-0.2-1.3-0.7-0.8-0.8-0.7-0.5-0.60.2-0.3-0.2-0.20.1-0.60.3-0.10.1
Delay disc. indifference point, 24s delay0.60.51.60.20.3-0.9-1.3-0.20.7-0.70.7-0.10.60.70.70.60.70.5-0.70.81.01.0-1.00.1-1.20.90.5
Delay disc. indifference point, 4s delay1.51.64.1-0.10.61.10.41.7-1.21.2-0.7-1.3-1.2-1.3-1.3-1.2-1.1-1.41.1-1.0-0.9-0.9-1.9-1.2-2.02.01.9
Delay disc. indifference point, 8s delay5.65.810.80.10.62.21.63.0-2.72.7-2.0-2.8-2.6-2.6-2.6-2.7-2.3-2.92.5-2.2-1.9-1.9-1.8-2.5-2.53.23.3
Indifference point function ln k3.44.78.4-0.50.92.92.62.6-2.82.7-2.7-1.9-2.6-2.4-2.4-2.4-2.4-2.52.4-2.3-2.3-2.3-0.6-1.4-0.71.11.5
Indifference point function log k3.44.78.4-0.50.92.92.62.6-2.82.7-2.7-1.9-2.6-2.4-2.4-2.4-2.4-2.52.4-2.3-2.3-2.3-0.6-1.4-0.71.11.5
Patch foraging total patch changes 0 sec1.93.18.82.3-2.21.01.30.8-1.41.60.4-1.0-2.0-2.0-2.0-1.8-2.2-1.91.6-2.1-2.2-2.2-0.1-3.0-0.61.52.0
Patch foraging total patch changes 12 sec0.60.84.81.9-2.2-0.9-0.2-1.20.7-0.52.10.40.30.10.10.00.00.3-0.60.20.10.10.8-0.90.6-0.4-0.1
Patch foraging total patch changes 18 sec0.70.93.90.8-1.1-1.3-0.9-1.41.2-1.12.01.21.00.70.70.80.71.0-1.10.80.60.60.60.10.5-0.6-0.6
Patch foraging total patch changes 24 sec1.41.73.40.9-1.01.01.00.9-1.21.3-0.1-1.2-1.2-1.4-1.4-1.3-1.5-1.41.8-1.8-1.7-1.7-0.7-1.9-0.71.31.5
Patch foraging total patch changes 6 sec0.30.52.51.4-1.5-0.8-0.5-1.00.7-0.51.60.40.10.20.20.20.20.3-0.70.40.20.20.6-0.70.4-0.2-0.0
Patch foraging time to switch 0 sec0.71.14.52.1-1.9-1.2-0.8-1.51.1-0.91.6-0.10.80.90.90.91.00.9-0.80.50.50.50.7-0.10.8-0.7-0.7
Patch foraging water rate 0 sec0.40.72.1-0.60.31.11.50.7-1.11.0-1.2-0.5-0.9-1.0-1.0-1.0-1.1-0.90.7-0.7-0.7-0.70.9-0.20.7-0.4-0.0
Patch foraging water rate 12 sec0.60.95.6-2.41.60.50.60.4-0.50.3-2.20.30.10.20.20.20.40.10.10.40.50.51.21.40.7-0.9-0.9
Patch foraging water rate 18 sec1.01.45.9-1.71.81.31.01.7-1.41.3-2.4-1.0-1.1-1.0-1.0-1.0-1.0-1.11.0-0.7-0.5-0.5-0.20.0-0.80.80.8
Patch foraging water rate 24 sec0.50.75.0-0.20.10.51.2-0.2-0.50.4-1.50.1-0.2-0.1-0.1-0.1-0.1-0.1-0.10.20.10.12.20.71.8-1.6-1.2
Patch foraging water rate 6 sec1.31.94.4-1.60.9-0.8-0.4-1.00.8-1.0-0.71.51.31.31.31.31.31.3-1.11.51.61.61.92.11.5-1.9-1.9
Seeking ratio, delayed vs. immediate footshock0.40.52.90.3-0.60.61.0-0.4-0.20.3-0.4-0.9-0.0-0.1-0.1-0.20.10.10.0-0.00.10.11.30.41.7-1.6-1.3
Distance traveled before self-admin0.20.20.60.6-0.40.40.50.3-0.50.5-0.5-0.6-0.2-0.4-0.4-0.4-0.5-0.50.7-0.8-0.8-0.8-0.1-0.5-0.00.30.3
Distance traveled after self-admin0.30.31.7-0.7-0.2-0.00.4-0.4-0.10.0-0.8-0.50.30.30.30.30.50.20.10.10.40.41.30.61.1-0.9-0.9
Extensor digitorum longus weight0.31.01.6-0.40.81.21.11.3-1.21.2-1.2-0.6-1.2-1.3-1.3-1.3-1.2-1.20.9-0.9-1.0-1.0-0.2-0.8-0.60.81.0
Bone: elastic displacement0.10.10.30.1-0.1-0.2-0.30.10.1-0.10.60.1-0.2-0.1-0.1-0.2-0.3-0.1-0.20.10.10.1-0.4-0.5-0.50.60.6
Bone: elastic work0.50.61.51.0-1.00.50.90.2-0.70.80.1-0.9-0.9-0.9-0.9-0.9-1.0-0.80.5-0.7-0.7-0.70.4-1.20.20.30.6
Bone: endosteal estimation0.10.10.9-1.00.50.30.40.1-0.20.2-0.70.50.0-0.0-0.00.00.1-0.00.20.00.00.00.50.50.5-0.5-0.5
Bone: endosteal perimeter0.00.10.2-0.50.1-0.00.1-0.10.0-0.0-0.1-0.00.10.10.10.10.10.1-0.10.30.40.40.30.20.3-0.3-0.3
Epididymis fat weight0.51.12.51.5-0.71.21.40.8-1.11.2-0.5-1.6-1.2-1.2-1.2-1.3-1.4-1.20.9-0.9-1.0-1.00.0-1.2-0.10.30.7
Delta time in closed arm before/after self-admin0.30.31.00.4-0.3-0.2-0.1-0.60.6-0.50.90.40.40.30.30.20.40.6-0.90.70.60.60.30.50.6-1.0-0.9
Delta time in open arm before/after self-admin0.90.93.7-0.90.81.51.60.9-1.31.1-1.9-0.6-0.8-0.8-0.8-0.8-0.6-0.81.0-0.7-0.6-0.60.60.40.8-0.7-0.5
Diff in mean of infusions in LGA sessions0.40.51.51.2-1.1-0.40.1-0.90.5-0.40.6-0.30.40.50.50.30.50.5-0.60.50.50.51.00.21.0-1.0-0.9
Delay discount exponential model param2.22.35.60.3-0.9-1.3-0.6-2.11.5-1.51.31.81.41.41.41.51.21.7-1.41.20.90.91.81.42.2-2.4-2.3
Extinction: sum of active levers before priming0.40.41.2-0.70.6-0.9-1.1-0.40.7-0.70.20.50.70.80.80.70.80.6-0.60.70.70.7-0.10.5-0.50.30.1
Active lever presses in extinction session 60.40.41.7-0.41.00.4-0.20.9-0.40.3-0.4-0.3-0.4-0.4-0.4-0.4-0.0-0.40.4-0.2-0.1-0.1-1.3-0.3-1.31.10.9
Bone: final force0.30.61.90.6-0.70.91.40.1-0.70.7-0.1-0.0-0.8-0.8-0.8-0.8-0.8-0.50.1-0.4-0.7-0.71.2-0.31.2-1.0-0.5
Bone: final moment0.30.41.50.4-0.60.71.20.0-0.60.6-0.00.0-0.7-0.7-0.7-0.7-0.7-0.4-0.0-0.2-0.5-0.51.2-0.31.1-0.9-0.4
Food consumed during 24 hour testing period0.20.32.7-1.71.10.1-0.10.20.0-0.1-0.71.00.30.30.30.30.20.20.10.10.00.0-0.10.8-0.1-0.2-0.4
Glucose0.30.51.4-0.30.41.11.20.8-0.90.8-0.8-0.6-0.9-0.9-0.9-0.9-0.9-0.70.2-0.3-0.4-0.40.4-0.00.4-0.4-0.1
Heart weight4.26.011.81.3-1.13.23.42.0-2.92.9-1.7-3.1-2.7-2.8-2.8-2.9-2.8-2.72.6-2.9-2.9-2.9-0.1-2.10.40.31.0
Delay discount hyperbolic model param2.32.45.2-0.0-0.6-1.4-0.8-2.01.6-1.61.12.01.61.61.61.61.31.8-1.51.21.01.01.81.52.0-2.3-2.2
Intermittent access intake day 1-15 change0.60.64.5-2.11.90.70.50.8-0.60.3-1.51.2-0.2-0.2-0.2-0.0-0.2-0.20.3-0.2-0.5-0.50.21.00.1-0.3-0.3
Intermittent access intake escalation0.70.74.5-2.11.80.40.30.4-0.20.0-1.31.50.20.20.20.30.10.2-0.00.1-0.1-0.10.31.30.5-0.7-0.8
Intermittent access intake escalation 21.61.611.9-3.43.50.5-0.11.1-0.3-0.0-2.02.10.20.20.20.40.10.2-0.00.3-0.1-0.1-0.61.8-0.60.0-0.3
Intermitt. access day 1 inactive lever presses0.50.63.11.7-1.50.40.6-0.1-0.20.40.9-0.9-0.6-0.6-0.6-0.4-0.9-0.40.6-0.9-1.0-1.0-0.3-1.10.20.00.2
Intermitt. access day 15 inactive lever presses0.30.31.00.9-0.6-0.3-0.1-0.70.6-0.51.00.60.30.40.40.30.30.5-0.70.50.30.30.20.30.8-0.9-0.8
Intermitt. access escalation Index0.30.31.31.1-1.1-0.30.2-0.70.1-0.10.2-0.00.1-0.0-0.00.00.00.1-0.2-0.1-0.2-0.21.1-0.31.0-0.6-0.4
Intermittent access day 1 total infusions0.50.52.41.6-1.6-0.7-0.4-1.00.7-0.51.4-0.20.30.50.50.40.40.4-0.60.40.50.50.5-0.40.7-0.5-0.4
Intermittent access day 15 total infusions0.10.10.7-0.2-0.0-0.1-0.0-0.40.3-0.30.30.80.20.30.30.40.20.4-0.40.20.00.00.40.40.7-0.7-0.6
Intermittent access terminal intake (last 3 days)0.20.21.0-1.00.70.20.20.0-0.1-0.0-0.50.90.10.20.20.2-0.10.2-0.20.1-0.1-0.10.40.70.5-0.6-0.6
Intermittent access total infusions0.10.10.30.4-0.5-0.00.0-0.30.2-0.10.50.00.00.20.20.20.00.2-0.20.10.10.10.1-0.00.5-0.5-0.4
Intermittent access day 1 locomotion1.01.04.82.2-1.80.30.40.1-0.40.61.1-1.1-0.9-0.8-0.8-0.9-1.0-0.80.6-1.0-1.0-1.0-0.5-1.8-0.20.81.0
Intermittent access day 15 total locomotion0.20.20.90.4-0.30.60.8-0.1-0.30.3-0.2-0.4-0.2-0.0-0.0-0.1-0.2-0.10.2-0.3-0.2-0.20.40.20.9-0.9-0.7
Intermittent access total locomotion0.10.11.11.0-0.7-0.00.0-0.30.2-0.10.7-0.20.00.20.20.1-0.00.1-0.1-0.1-0.1-0.1-0.3-0.20.3-0.2-0.2
Intermittent access standard deviation0.20.21.1-1.11.00.50.30.4-0.40.3-1.00.6-0.1-0.1-0.10.2-0.1-0.10.3-0.2-0.4-0.40.10.60.3-0.4-0.4
Left kidney weight3.08.413.00.40.63.42.63.5-3.13.1-1.3-2.6-3.5-3.6-3.6-3.4-3.6-3.22.7-2.9-3.0-3.0-2.7-2.8-2.42.63.0
Right kidney weight5.013.919.11.10.14.13.04.3-3.83.9-1.6-3.7-4.2-4.4-4.4-4.2-4.3-4.13.7-4.0-4.1-4.1-3.6-3.9-3.23.74.1
Cocaine induced anxiety1.01.24.50.8-0.11.10.51.2-0.70.80.7-0.6-1.2-1.1-1.1-1.2-1.2-1.00.7-1.0-1.2-1.2-2.1-1.2-1.41.21.3
Post-drug Anxiety0.60.61.3-0.40.71.10.61.1-0.80.8-0.5-0.3-0.8-0.9-0.9-0.8-1.0-0.80.7-0.8-0.9-0.9-1.1-0.4-0.80.70.7
Baseline Anxiety0.20.21.4-0.60.40.30.60.2-0.40.4-1.2-0.2-0.2-0.2-0.2-0.1-0.3-0.20.2-0.00.00.01.00.30.6-0.4-0.3
Tail length0.10.41.3-0.90.81.11.10.7-0.70.6-0.9-0.1-0.5-0.7-0.7-0.6-0.7-0.40.5-0.3-0.2-0.20.10.30.3-0.5-0.4
Length with tail0.51.93.90.6-0.32.01.91.3-1.61.7-0.9-0.9-1.7-1.6-1.6-1.5-1.5-1.51.6-1.7-1.7-1.7-0.4-1.1-0.00.20.6
Length without tail0.71.53.41.8-1.71.01.30.5-1.21.3-0.5-1.0-1.3-1.2-1.2-1.1-1.0-1.31.4-1.7-1.7-1.70.3-1.60.40.40.7
Times rat made contact with spout0.40.50.90.1-0.20.60.60.7-0.70.7-0.1-0.4-0.9-0.9-0.9-0.9-0.9-0.90.7-0.8-0.8-0.8-0.3-1.0-0.50.70.9
Lifetime Intake0.10.10.30.2-0.4-0.4-0.4-0.50.4-0.40.50.10.30.40.40.50.30.3-0.30.20.30.30.10.00.3-0.2-0.2
Liver weight, left2.23.69.5-0.50.42.62.62.0-2.52.4-3.1-2.3-1.8-1.8-1.8-1.7-1.8-2.02.7-2.2-1.9-1.90.2-0.80.20.40.6
Liver weight, right1.93.24.5-0.40.32.01.42.1-2.02.0-1.2-1.7-2.0-1.9-1.9-1.9-2.0-2.02.1-2.0-1.8-1.8-1.5-1.7-1.41.82.0
Locomotor activity0.10.10.5-0.4-0.1-0.5-0.7-0.20.5-0.40.50.20.40.50.50.40.30.30.00.10.20.2-0.50.1-0.60.40.2
Locomotor testing distance0.20.41.0-0.4-0.0-0.9-1.0-0.50.9-0.80.90.60.60.80.80.60.60.7-0.60.60.50.5-0.30.2-0.50.20.0
Locomotor testing rearing1.32.03.50.1-0.4-1.6-1.4-1.61.8-1.71.51.91.51.71.71.61.51.7-1.71.41.21.20.51.20.6-1.1-1.3
Locomotion in novel chamber0.70.81.80.6-0.40.90.90.8-1.01.1-0.4-1.3-1.3-1.2-1.2-1.2-0.8-1.20.7-0.8-0.7-0.70.0-1.2-0.20.60.9
Locomotion in novel chamber post-restriction1.11.34.9-0.60.21.51.61.0-1.51.5-2.1-2.2-0.9-1.1-1.1-0.9-0.8-1.11.6-1.2-0.7-0.70.4-0.30.50.00.1
Fecal boli incidents, locomotor time 10.40.41.3-0.50.9-0.9-1.1-0.10.6-0.60.20.90.60.60.60.70.60.4-0.40.60.50.5-0.50.4-1.00.80.5
Change in fecal boli incidents, locomotor task2.22.14.50.2-0.32.02.11.4-1.81.8-1.2-1.4-1.7-1.7-1.7-1.8-1.9-1.61.5-1.6-1.7-1.7-0.2-1.10.20.10.5
Time >=10cm from walls, locomotor time 10.20.20.7-0.80.2-0.2-0.0-0.40.2-0.3-0.20.60.30.40.40.40.30.4-0.30.30.20.20.90.60.8-0.8-0.8
Bouts of movement, locomotor time 12.22.45.5-1.60.8-2.1-2.3-1.21.8-1.81.01.71.91.91.91.91.91.6-1.41.51.71.7-0.11.3-0.60.2-0.4
Total resting periods, locomotor time 12.42.65.3-1.00.4-2.2-2.3-1.52.0-2.01.31.72.02.02.02.02.01.8-1.61.71.81.80.11.3-0.1-0.3-0.7
Rest time, locomotor task time 10.10.10.40.7-0.6-0.10.0-0.20.1-0.00.4-0.2-0.0-0.1-0.1-0.0-0.10.0-0.1-0.2-0.3-0.30.1-0.20.2-0.1-0.1
Distance moved, locomotor task time 10.30.30.5-0.2-0.4-0.7-0.5-0.70.6-0.60.70.60.50.50.50.30.40.5-0.60.60.70.70.70.10.4-0.4-0.3
Vertical activity count, locomotor time 10.10.10.8-0.1-0.40.10.4-0.2-0.20.2-0.6-0.50.00.10.1-0.00.2-0.10.3-0.10.20.20.90.10.8-0.5-0.4
Time >=10cm from walls, locomotor time 28.08.516.72.2-2.13.53.62.2-3.33.4-1.8-4.1-3.3-3.3-3.3-3.2-3.1-3.23.4-3.5-3.3-3.3-0.1-3.10.40.81.6
Bouts of movement, locomotor time 20.30.32.7-0.1-0.6-0.10.4-0.5-0.20.2-0.7-0.50.1-0.0-0.00.2-0.0-0.10.6-0.5-0.2-0.21.6-0.01.2-0.6-0.5
Total resting periods, locomotor time 20.30.32.9-0.1-0.6-0.30.2-0.6-0.10.1-0.6-0.50.20.20.20.40.20.10.5-0.3-0.1-0.11.70.11.3-0.7-0.6
Rest time, locomotor task time 23.64.16.6-0.90.8-2.4-2.6-1.82.5-2.51.92.32.32.32.32.32.42.4-2.62.42.12.1-0.12.0-0.0-0.9-1.4
Distance moved, locomotor task time 21.61.83.31.3-1.41.51.60.9-1.41.5-0.3-1.8-1.6-1.7-1.7-1.7-1.5-1.51.4-1.4-1.2-1.2-0.1-1.80.00.51.0
Vertical activity count, locomotor time 23.03.37.41.8-1.82.12.50.9-2.12.2-1.5-2.7-2.0-2.0-2.0-1.8-1.8-1.91.9-2.0-1.7-1.71.2-1.71.3-0.20.4
Light reinforcement 11.42.517.44.2-4.10.01.0-1.1-0.10.52.2-1.6-1.0-1.0-1.0-0.9-1.1-0.70.2-0.7-0.8-0.81.3-2.41.3-0.50.3
Light reinforcement 21.11.53.50.5-1.1-1.4-1.2-1.51.4-1.31.90.71.11.31.31.11.31.3-1.41.41.51.50.70.50.7-0.9-0.9
Bone: marrow area0.10.10.8-0.90.40.40.40.2-0.30.3-0.70.4-0.1-0.1-0.1-0.1-0.1-0.10.2-0.1-0.1-0.10.50.40.4-0.4-0.4
Bone: maximum diameter0.50.92.30.4-0.51.21.50.6-1.21.2-1.1-1.0-1.1-1.1-1.1-1.1-1.0-1.11.1-1.0-1.0-1.00.7-0.80.6-0.10.2
Bone: maximum force1.22.03.90.9-0.71.82.01.1-1.61.7-0.6-0.9-1.8-1.8-1.8-1.8-1.8-1.61.2-1.5-1.8-1.80.2-1.50.20.20.7
Bone: maximum moment0.91.63.00.6-0.61.61.71.1-1.41.5-0.5-0.8-1.6-1.7-1.7-1.7-1.7-1.51.1-1.4-1.5-1.50.0-1.40.10.30.8
Mean time between licks in bursts0.60.93.8-1.91.4-0.8-1.3-0.10.8-0.90.32.00.80.80.80.80.80.8-0.60.60.60.6-0.80.9-0.90.4-0.0
Mean num. licks in bursts0.70.82.31.2-1.40.60.70.3-0.50.71.0-0.6-1.0-1.0-1.0-1.0-1.0-0.80.6-0.9-1.1-1.1-0.5-1.5-0.20.40.8
Cd content in liver0.30.30.6-0.30.10.60.50.6-0.70.7-0.8-0.8-0.6-0.6-0.6-0.5-0.6-0.60.7-0.6-0.5-0.5-0.0-0.4-0.20.40.5
Co content in liver0.30.41.5-0.81.20.2-0.40.8-0.20.2-0.50.4-0.3-0.3-0.3-0.2-0.4-0.30.0-0.1-0.1-0.1-1.10.0-1.21.10.8
Cu content in liver0.80.94.0-2.01.5-0.4-0.6-0.20.5-0.7-0.71.50.80.90.91.00.90.8-0.70.90.90.90.41.60.3-0.8-1.0
Fe content in liver4.35.29.40.6-1.8-2.3-1.3-3.12.4-2.32.22.02.32.32.32.42.32.4-2.42.22.22.22.61.62.6-2.8-2.7
K content in liver0.50.52.1-0.40.90.80.51.0-0.80.7-1.4-0.8-0.5-0.5-0.5-0.6-0.5-0.60.8-0.7-0.6-0.6-0.60.0-0.60.60.5
Mg content in liver1.11.26.2-1.21.71.51.21.5-1.41.2-2.5-0.4-1.0-0.9-0.9-0.9-0.8-1.00.9-0.8-1.0-1.0-0.10.3-0.20.20.2
Mn content in liver1.01.22.0-0.30.51.30.91.4-1.21.2-0.6-0.9-1.3-1.3-1.3-1.4-1.1-1.21.0-1.0-1.0-1.0-1.1-1.0-0.91.01.2
Na content in liver1.92.03.7-0.50.2-1.4-1.4-1.41.6-1.60.81.31.81.81.81.81.91.8-1.31.31.31.30.31.80.6-1.2-1.6
Rb content in liver4.75.89.9-0.51.43.12.63.0-3.12.9-3.1-1.8-2.9-2.8-2.8-2.8-2.7-2.82.4-2.4-2.5-2.5-0.8-1.5-0.91.41.8
Se content in liver0.10.20.7-0.80.60.60.50.5-0.50.4-0.50.1-0.5-0.5-0.5-0.4-0.5-0.30.1-0.1-0.2-0.20.20.10.1-0.1-0.0
Sr content in liver0.30.31.6-0.60.4-0.1-0.70.40.0-0.00.2-0.0-0.1-0.1-0.10.1-0.1-0.20.4-0.2-0.1-0.1-1.3-0.3-1.11.10.9
Zn content in liver0.50.51.4-0.60.5-0.6-0.7-0.50.7-0.7-0.20.71.01.01.01.01.00.9-0.40.60.70.70.01.20.2-0.6-0.9
Bone: minimum diameter2.03.75.6-0.40.61.91.32.3-2.12.0-1.3-1.4-2.2-2.2-2.2-2.2-2.1-2.22.1-2.0-1.9-1.9-1.6-2.0-1.72.22.4
Time in familiar zone, hab. session 11.11.02.2-1.00.9-1.1-1.3-0.70.9-1.0-0.40.61.31.41.41.51.41.1-0.60.91.21.20.11.3-0.0-0.2-0.7
Time in novel zone, hab. session 11.41.42.81.3-1.21.21.60.6-1.11.20.3-0.7-1.5-1.6-1.6-1.7-1.6-1.20.6-1.0-1.3-1.30.4-1.50.5-0.10.5
Total zone transitions, hab. session 10.20.31.10.10.4-0.5-0.9-0.00.4-0.4-0.00.30.60.60.60.60.60.40.10.10.20.2-1.00.3-0.90.70.3
Total locomotion distance, hab. session 10.20.32.10.10.4-0.3-0.90.20.3-0.30.3-0.10.40.40.40.40.40.20.0-0.00.10.1-1.50.0-1.20.90.5
Locomotion velocity, hab. session 10.30.42.50.20.2-0.6-1.2-0.00.6-0.50.60.10.60.60.60.60.60.4-0.10.10.20.2-1.60.0-1.31.00.5
Time in familiar zone, hab. session 20.10.10.70.1-0.3-0.20.1-0.3-0.10.0-0.6-0.30.20.20.20.30.20.00.30.00.30.30.80.10.6-0.2-0.2
Time in novel zone, hab. session 20.60.61.30.20.00.90.70.8-0.60.60.4-0.1-1.0-1.1-1.1-1.1-1.1-0.70.2-0.6-0.9-0.9-0.8-0.8-0.60.50.7
Total zone transitions, hab. session 20.30.32.1-0.81.20.1-0.50.7-0.10.0-0.6-0.10.10.20.20.20.2-0.00.4-0.2-0.1-0.1-1.40.3-1.21.00.6
Total locomotion distance, hab. session 20.10.10.90.20.10.3-0.10.4-0.10.20.0-0.6-0.1-0.1-0.1-0.0-0.1-0.20.3-0.3-0.2-0.2-0.9-0.2-0.60.50.3
Locomotion velocity, hab. session 20.10.10.90.3-0.00.0-0.30.20.0-0.00.2-0.50.10.10.10.20.1-0.00.2-0.2-0.1-0.1-1.0-0.1-0.60.50.3
Novel to familiar place preference ratio1.11.23.71.6-1.51.01.30.4-1.01.10.2-1.9-1.2-1.2-1.2-1.2-1.2-1.11.0-1.0-0.8-0.80.1-1.50.50.10.5
Novelty place preference1.11.13.41.4-1.41.01.20.4-1.01.10.2-1.8-1.2-1.2-1.2-1.2-1.2-1.11.0-1.0-0.8-0.80.0-1.50.40.20.6
Time in novel zone, NPP test1.01.03.21.4-1.41.01.20.3-0.91.00.3-1.8-1.1-1.1-1.1-1.2-1.1-1.00.9-0.9-0.7-0.70.2-1.40.50.00.5
Total zone transitions, NPP test0.71.05.7-1.82.4-0.3-1.20.70.4-0.6-0.71.00.70.70.70.70.70.5-0.40.50.40.4-1.81.2-1.60.90.3
Total locomotion distance, NPP test0.71.06.1-1.32.00.5-0.51.3-0.30.2-0.40.3-0.3-0.3-0.3-0.2-0.3-0.30.2-0.2-0.3-0.3-2.50.2-2.01.51.1
Locomotion velocity, NPP test0.81.17.1-1.42.10.5-0.71.4-0.20.1-0.40.3-0.3-0.3-0.3-0.2-0.3-0.30.2-0.3-0.4-0.4-2.70.1-2.21.71.2
Intraocular pressure0.81.23.2-0.6-0.4-1.8-1.5-1.31.4-1.31.31.71.11.11.11.10.91.1-1.21.10.90.90.80.30.1-0.1-0.2
Delta distance traveled before/after self-admin0.40.50.9-0.6-0.2-0.6-0.4-0.80.6-0.60.20.10.50.60.60.70.90.7-0.60.70.90.90.90.70.8-0.8-0.9
Delta ambulatory time before/after self-admin0.60.71.30.2-1.0-0.9-0.6-1.10.9-0.81.0-0.20.70.70.70.71.00.8-0.80.81.01.00.80.40.9-0.9-0.9
Parametrial fat weight0.20.30.80.6-0.50.50.20.3-0.40.40.1-0.9-0.4-0.4-0.4-0.3-0.3-0.40.7-0.8-0.8-0.8-0.8-0.7-0.40.50.5
Pavlov. Cond. lever latency0.20.31.3-1.10.40.40.60.2-0.50.4-1.10.3-0.2-0.2-0.2-0.2-0.2-0.30.3-0.1-0.1-0.11.20.30.7-0.5-0.3
Pavlov. Cond. magazine entry latency1.01.311.13.3-2.8-0.10.5-0.90.3-0.12.2-1.6-0.3-0.3-0.3-0.3-0.30.0-0.4-0.00.10.10.4-1.20.9-0.7-0.3
Pavlov. Cond. change in total contacts0.20.20.91.0-0.50.20.2-0.30.3-0.20.8-0.40.10.10.10.00.10.4-0.50.30.30.3-0.20.30.4-0.7-0.6
Pavlov. Cond. index score0.40.64.32.1-1.4-0.6-0.5-0.80.7-0.61.6-0.80.40.30.30.30.30.5-0.60.40.50.5-0.4-0.4-0.0-0.1-0.1
Pavlov. Cond. latency score0.40.54.72.2-1.4-0.4-0.4-0.50.5-0.31.6-1.00.10.10.10.10.10.2-0.2-0.00.10.1-0.7-0.7-0.30.30.3
Pavlov. Cond. lever contacts0.30.31.41.1-0.4-0.4-0.7-0.30.6-0.51.2-0.20.40.30.30.30.30.4-0.30.10.10.1-1.1-0.2-0.70.40.2
Pavlov. Cond. magazine entry number0.60.87.2-2.72.00.0-0.40.6-0.20.0-1.81.60.30.30.30.40.30.00.4-0.1-0.2-0.2-0.11.0-0.50.40.1
Pavlov. Cond. intertrial magazine entries1.01.23.9-1.60.6-0.7-0.2-0.90.5-0.6-1.02.01.11.01.01.11.00.9-0.50.50.20.22.01.51.5-1.4-1.4
Pavlov. Cond. lever-magazine prob. diff.0.40.52.61.6-1.0-0.6-0.6-0.60.8-0.61.5-0.60.40.40.40.30.40.5-0.70.50.60.6-0.6-0.2-0.2-0.0-0.1
Pavlov. Cond. response bias0.60.73.11.8-1.2-0.6-0.4-1.00.9-0.81.7-0.40.50.50.50.50.50.8-1.00.80.80.80.10.10.5-0.8-0.7
Pavlov. Cond. lever latency2.12.88.1-2.82.8-1.4-2.3-0.21.4-1.6-0.12.31.71.71.71.71.71.5-1.21.61.71.7-1.32.1-1.40.5-0.3
Pavlov. Cond. magazine entry latency1.41.68.42.9-2.9-0.21.0-1.40.3-0.11.4-0.8-0.0-0.1-0.1-0.1-0.10.2-0.60.1-0.0-0.02.1-0.62.3-1.8-1.2
Pavlov. Cond. change in total contacts1.01.47.52.6-2.70.21.2-1.20.00.21.1-1.1-0.1-0.2-0.2-0.2-0.20.1-0.1-0.2-0.2-0.21.9-0.62.2-1.8-1.2
Pavlov. Cond. index score1.41.89.52.8-3.10.41.6-1.1-0.30.51.0-1.3-0.5-0.6-0.6-0.6-0.6-0.3-0.0-0.4-0.5-0.52.3-1.02.5-1.9-1.1
Pavlov. Cond. latency score1.21.57.42.5-2.70.41.5-1.0-0.20.40.9-1.2-0.5-0.5-0.5-0.5-0.5-0.2-0.1-0.3-0.4-0.42.1-0.82.3-1.8-1.1
Pavlov. Cond. lever contacts1.62.210.43.0-3.20.91.9-0.4-0.91.20.5-2.1-1.2-1.2-1.2-1.2-1.2-1.11.0-1.2-1.1-1.11.7-1.91.7-0.8-0.0
Pavlov. Cond. magazine entry number1.11.37.0-2.62.5-0.2-1.31.1-0.0-0.2-1.00.80.30.30.30.30.3-0.00.30.10.20.2-1.90.5-2.11.81.2
Pavlov. Cond. intertrial magazine entries1.11.43.3-1.41.50.90.21.7-1.11.0-1.5-0.5-1.0-1.0-1.0-1.0-0.9-1.21.2-0.9-0.8-0.8-1.4-0.6-1.71.81.6
Pavlov. Cond. lever-magazine prob. diff.1.41.89.22.8-3.00.31.6-1.2-0.20.41.0-1.2-0.4-0.5-0.5-0.5-0.5-0.2-0.1-0.3-0.4-0.42.3-0.92.5-1.9-1.1
Pavlov. Cond. response bias1.92.613.43.4-3.70.72.0-0.9-0.71.00.8-2.0-0.9-1.0-1.0-1.0-1.0-0.80.6-0.9-0.8-0.82.4-1.62.5-1.6-0.7
Time in closed arm before self-admin1.41.53.50.2-0.6-1.9-1.6-1.61.5-1.50.91.21.51.51.51.71.41.4-1.21.21.21.20.90.80.4-0.5-0.7
Time in closed arm after self-admin2.22.24.61.7-1.7-1.8-1.1-2.21.8-1.61.80.91.51.31.31.51.21.6-1.81.41.31.31.50.61.3-1.4-1.4
Time in open arm before self-admin0.50.51.00.2-0.20.60.70.6-0.80.8-0.3-0.6-1.0-0.9-0.9-0.9-0.9-0.90.6-0.7-0.8-0.80.0-0.9-0.20.50.8
Time in open arm after self-admin2.12.35.7-1.51.42.32.11.9-2.11.9-2.4-0.9-1.8-1.6-1.6-1.8-1.4-1.61.7-1.2-1.3-1.30.1-0.20.20.00.4
Bone: periosteal estimation0.51.02.0-0.30.11.31.41.0-1.31.3-1.2-0.6-1.2-1.2-1.2-1.2-1.2-1.21.1-1.0-0.9-0.90.3-0.70.20.20.5
Bone: periosteal perimeter0.71.21.9-0.20.21.21.01.3-1.31.3-0.8-0.9-1.4-1.4-1.4-1.4-1.3-1.31.1-1.0-0.9-0.9-0.5-1.1-0.60.91.1
Bone: post-yield work0.20.21.5-0.60.90.3-0.20.6-0.10.0-0.20.5-0.0-0.1-0.1-0.0-0.0-0.00.2-0.2-0.2-0.2-1.20.3-0.90.50.3
Progressive ratio test 1 active lever presses0.50.51.91.1-1.4-0.5-0.1-1.10.6-0.51.2-0.10.30.50.50.50.30.5-0.50.30.30.30.8-0.11.4-1.0-0.8
Progressive ratio test 1 breakpoint0.50.51.50.8-1.0-0.5-0.2-1.00.6-0.61.10.10.50.60.60.60.40.6-0.60.50.50.50.60.21.2-1.0-0.9
Progressive ratio test 1 inactive lever presses0.70.82.51.1-1.2-0.7-0.5-1.20.9-0.81.60.50.60.70.70.80.60.9-0.90.80.60.60.70.31.1-1.2-1.0
Progressive ratio test 2 active lever presses1.21.22.61.0-1.1-0.9-0.5-1.51.2-1.11.40.70.91.01.01.00.91.2-1.21.00.90.91.00.71.6-1.6-1.5
Progressive ratio test 2 breakpoint1.21.33.71.5-1.6-0.9-0.2-1.71.1-0.91.50.40.80.90.90.80.81.0-1.10.90.80.81.40.41.9-1.8-1.6
Progressive ratio test 2 inactive lever presses0.20.31.00.8-0.7-0.10.2-0.60.4-0.30.90.40.10.20.20.20.10.4-0.60.30.20.20.60.20.9-1.0-0.8
Incentive Sensitization - Responses0.10.10.3-0.00.00.10.3-0.20.0-0.00.10.50.00.00.0-0.1-0.10.1-0.30.1-0.1-0.10.40.20.6-0.6-0.4
Incentive Sensitization - Breakpoint0.10.10.50.2-0.20.00.3-0.30.1-0.10.20.40.00.10.1-0.0-0.00.2-0.30.2-0.0-0.00.50.20.7-0.7-0.5
Sum of active levers in priming session hrs 5-60.20.21.3-1.21.1-0.0-0.20.10.2-0.3-0.50.60.20.50.50.20.40.3-0.20.40.40.4-0.00.80.0-0.3-0.4
Progressive ratio0.20.20.7-0.70.0-0.4-0.3-0.50.4-0.4-0.30.00.80.50.50.80.30.50.10.00.10.10.30.60.3-0.3-0.5
Food seeking constrained by brief footshock0.00.00.1-0.1-0.3-0.0-0.1-0.0-0.00.00.4-0.1-0.00.00.00.0-0.0-0.10.2-0.10.00.0-0.3-0.3-0.20.20.2
Seeking ratio, punishment vs. effort0.10.10.80.6-0.5-0.2-0.2-0.10.2-0.10.90.2-0.20.10.1-0.20.2-0.0-0.40.40.30.3-0.1-0.4-0.20.20.3
Retroperitoneal fat weight2.37.715.92.9-2.63.34.01.6-3.13.3-1.7-3.6-3.1-2.9-2.9-3.0-2.9-3.03.0-3.2-3.2-3.21.1-2.81.4-0.10.8
Reaction time number correct2.02.96.8-0.60.62.52.61.8-2.32.2-2.5-1.8-1.8-1.9-1.9-1.7-2.1-1.81.8-1.6-1.5-1.50.4-0.60.4-0.10.3
Reaction time mean minus median0.70.92.11.1-0.71.01.10.7-1.11.2-0.8-1.4-1.0-0.7-0.7-1.1-0.7-1.11.2-1.1-0.9-0.90.1-1.10.10.40.6
Reaction time mean minus median AUC2.02.64.41.7-0.91.92.01.4-1.92.0-1.1-2.0-1.9-1.7-1.7-2.1-1.6-1.91.8-1.8-1.7-1.7-0.2-1.8-0.00.71.2
Reaction time num false alarms0.10.10.70.8-0.3-0.1-0.1-0.10.3-0.20.90.80.1-0.2-0.20.1-0.40.2-0.50.1-0.2-0.2-0.5-0.2-0.1-0.00.0
Reaction time num false alarms AUC0.20.31.00.8-0.5-0.4-0.2-0.60.6-0.60.91.00.50.30.30.50.00.6-0.80.40.20.20.10.20.4-0.5-0.5
Reaction time trials correct on left2.02.96.8-0.60.62.52.61.8-2.32.2-2.5-1.8-1.8-1.9-1.9-1.7-2.1-1.81.8-1.6-1.5-1.50.4-0.60.4-0.10.3
Reaction time trials on left2.02.86.8-0.50.52.52.61.8-2.32.2-2.4-1.8-1.8-1.9-1.9-1.7-2.1-1.81.8-1.6-1.5-1.50.5-0.60.5-0.10.3
Reaction time mean1.11.53.20.7-0.9-1.4-0.7-1.71.2-1.10.60.31.31.41.41.31.41.2-1.11.21.31.31.80.91.5-1.4-1.4
Reaction time mean AUC0.60.72.20.8-0.8-0.9-0.4-1.20.7-0.70.20.00.90.90.90.81.00.8-0.70.70.80.81.50.51.2-1.0-1.0
Median of all reaction times2.63.55.80.5-0.8-2.2-1.5-2.42.0-2.01.21.12.12.12.12.22.12.1-1.92.02.12.12.01.51.7-1.9-2.0
Reaction time omissions0.40.53.71.9-1.10.30.40.1-0.30.50.7-0.8-0.8-0.5-0.5-0.6-0.6-0.60.2-0.5-0.4-0.4-0.3-1.2-0.20.40.6
Reaction time false alarm rate0.81.23.50.9-0.8-1.4-1.3-1.31.5-1.41.91.51.11.01.01.10.81.2-1.41.00.80.8-0.20.30.1-0.3-0.4
Reaction time premature initiation rate1.82.45.12.2-2.1-1.7-1.1-2.31.8-1.62.20.71.51.61.61.61.41.6-1.31.01.01.01.00.51.3-1.4-1.5
Reaction time premature initiations0.50.83.41.8-1.7-0.30.3-1.20.5-0.40.9-0.20.50.50.50.60.30.6-0.40.20.10.11.20.21.5-1.4-1.3
Std. dev. reaction times0.50.71.91.4-1.10.61.00.2-0.91.0-0.5-1.4-0.9-0.6-0.6-0.9-0.6-0.90.9-0.9-0.7-0.70.6-1.20.40.20.5
Reaction time trials completed2.02.86.8-0.50.52.52.61.8-2.32.2-2.4-1.8-1.8-1.9-1.9-1.7-2.1-1.81.8-1.6-1.5-1.50.5-0.60.5-0.10.3
Reaction time trials AUC1.72.46.7-0.40.32.32.61.4-2.12.0-2.3-1.8-1.6-1.7-1.7-1.5-1.9-1.61.6-1.4-1.3-1.30.9-0.40.9-0.5-0.1
Run reversals in cocaine runway, females0.40.42.6-1.61.40.50.20.5-0.20.1-1.10.50.10.10.10.10.20.10.10.20.20.20.11.0-0.1-0.4-0.6
Run reversals in cocaine runway, males1.11.14.6-1.10.6-1.1-1.3-0.71.2-1.20.92.11.01.01.01.21.01.1-1.11.10.90.9-0.21.0-0.2-0.3-0.5
Latency to leave start box in cocaine runway0.40.41.70.8-1.2-0.50.0-1.00.5-0.40.5-0.10.60.30.30.60.30.5-0.20.20.20.21.10.21.3-1.0-1.0
Latency to leave start box in cocaine runway, F0.10.10.20.2-0.3-0.3-0.4-0.10.2-0.10.3-0.10.30.00.00.2-0.10.10.1-0.1-0.1-0.1-0.5-0.2-0.40.50.3
Latency to leave start box in cocaine runway, M1.61.57.01.1-1.9-0.30.5-1.60.6-0.50.7-0.00.70.40.40.80.50.8-0.50.50.50.52.30.62.6-2.4-2.1
Std. dev. time between licks in bursts1.92.33.3-0.00.31.51.21.8-1.71.6-1.0-1.0-1.7-1.7-1.7-1.7-1.7-1.81.6-1.7-1.7-1.7-1.2-1.6-1.31.71.8
Total sessions with >9 infusions0.50.52.30.6-0.5-0.2-0.60.3-0.00.11.0-0.7-0.4-0.3-0.3-0.3-0.3-0.50.4-0.4-0.2-0.2-1.3-1.3-1.31.51.4
Short access day 1 total inactive lever presses0.20.30.6-0.2-0.20.50.60.4-0.50.5-0.5-0.5-0.5-0.5-0.5-0.4-0.7-0.50.6-0.8-0.8-0.80.1-0.4-0.30.30.3
Short access day 10 total inactive lever presses0.30.31.31.0-0.21.10.90.5-0.40.40.5-0.4-0.6-0.7-0.7-0.7-0.6-0.20.0-0.3-0.4-0.4-0.9-0.1-0.0-0.5-0.4
Short access day 1 total infusions0.40.41.4-0.4-0.0-1.0-1.2-0.50.8-0.70.80.50.60.70.70.70.60.5-0.40.50.60.6-0.40.0-0.60.50.3
Short access day 10 total infusions0.20.21.61.2-1.3-0.00.0-0.3-0.00.10.6-1.0-0.2-0.1-0.1-0.0-0.2-0.20.4-0.4-0.2-0.2-0.1-0.80.20.20.3
Short access total infusions0.10.10.30.2-0.6-0.5-0.5-0.40.3-0.20.3-0.30.20.30.30.40.20.10.10.00.20.20.1-0.3-0.00.30.2
Short access day 1 locomotion0.50.51.41.2-1.0-1.0-0.8-1.00.8-0.71.1-0.20.60.70.70.70.70.6-0.60.60.70.70.3-0.20.2-0.2-0.2
Short access day 10 total locomotion0.91.14.0-1.51.80.5-0.31.5-0.60.5-0.70.1-0.5-0.4-0.4-0.5-0.5-0.70.7-0.5-0.5-0.5-2.0-0.3-1.91.81.5
Short access total locomotion0.60.62.11.4-1.10.1-0.10.2-0.20.41.0-1.2-0.6-0.5-0.5-0.5-0.5-0.60.6-0.7-0.5-0.5-1.1-1.5-0.81.21.2
One hour access (0.3 mA shock)1.01.23.6-1.20.8-0.30.0-0.70.6-0.7-0.31.30.80.90.90.90.81.0-1.01.10.90.91.21.71.7-1.9-1.9
Compulsive drug intake0.60.62.5-1.00.3-0.30.2-0.60.2-0.3-0.90.40.60.60.60.60.60.5-0.30.50.60.61.61.11.2-1.2-1.2
One hour access (shock baseline)0.30.31.61.0-0.6-0.4-0.4-0.60.6-0.61.30.60.30.40.40.40.30.5-0.70.40.30.3-0.20.10.5-0.6-0.5
Social response proportion2.42.611.13.3-2.8-0.50.5-2.00.9-0.71.3-1.10.60.90.90.80.81.0-1.20.80.90.92.30.42.9-2.8-2.3
Social responses3.95.010.32.4-2.9-2.0-0.7-3.22.2-2.02.30.61.91.71.71.91.82.1-2.32.12.12.13.21.13.1-3.1-2.8
Social time0.50.73.50.6-1.2-0.50.3-1.20.4-0.4-0.10.20.60.50.50.60.40.5-0.20.20.10.11.90.41.7-1.4-1.2
Soleus weight0.20.72.70.6-0.7-0.60.0-1.10.5-0.5-0.00.10.80.70.70.70.80.7-0.50.60.60.61.60.61.4-1.3-1.2
Bone: stiffness0.81.22.60.8-0.61.51.60.9-1.21.3-0.5-0.7-1.3-1.3-1.3-1.3-1.3-1.21.0-1.4-1.6-1.6-0.0-1.00.20.00.4
Tibialis anterior weight0.31.05.41.5-1.3-0.11.0-1.10.00.0-0.3-0.80.40.40.40.30.40.3-0.20.20.20.22.30.32.1-1.8-1.4
Time to tail flick, vehicle, before self-admin0.90.91.9-0.20.40.90.61.2-1.01.0-0.7-1.4-1.0-0.9-0.9-0.9-1.0-1.11.2-1.0-0.8-0.8-1.2-0.9-0.91.21.2
Time to tail flick, vehicle, after self-admin0.40.41.3-1.00.70.60.70.7-0.80.7-1.10.2-0.5-0.6-0.6-0.5-0.7-0.60.6-0.6-0.8-0.80.2-0.10.00.20.3
Time to tail flick, test, before self-admin0.40.40.80.7-0.90.60.70.2-0.50.60.4-0.7-0.8-0.8-0.8-0.6-0.9-0.60.6-0.7-0.6-0.6-0.1-0.90.20.10.4
Time to tail flick, test, after self-admin0.40.50.9-0.0-0.20.90.90.6-0.90.9-0.7-0.9-0.8-0.8-0.8-0.7-0.7-0.80.9-0.8-0.7-0.70.1-0.50.30.10.2
Delta time to tail flick, vehicle, before/after SA0.40.41.1-0.70.40.81.00.3-0.60.5-1.10.4-0.3-0.4-0.4-0.4-0.5-0.30.3-0.4-0.6-0.61.00.30.7-0.8-0.5
Delta time to tail flick, test, before/after SA0.10.10.50.3-0.10.20.30.2-0.40.4-0.7-0.5-0.2-0.2-0.2-0.3-0.2-0.40.4-0.4-0.4-0.40.2-0.3-0.00.30.3
Tibia length0.92.65.42.0-1.21.40.91.3-1.21.40.7-1.7-1.9-1.8-1.8-1.8-1.7-1.61.3-1.7-1.7-1.7-1.7-2.3-1.31.71.9
Ambulatory time before self-admin0.40.41.21.1-0.50.40.50.4-0.50.6-0.2-0.7-0.4-0.5-0.5-0.6-0.7-0.70.7-0.8-0.9-0.9-0.4-0.9-0.40.70.8
Ambulatory time after self-admin0.60.61.2-0.4-0.2-0.7-0.4-0.90.7-0.70.20.30.90.70.70.81.00.9-0.80.91.01.01.00.90.9-1.1-1.1
Bone: tissue strength0.50.51.2-0.10.30.80.40.9-0.60.60.1-0.0-0.7-0.8-0.8-0.8-0.8-0.60.4-0.7-0.8-0.8-1.1-0.6-0.80.70.8
Total heroin consumption0.40.52.3-0.91.40.3-0.31.0-0.30.3-0.5-0.2-0.3-0.3-0.3-0.4-0.1-0.40.3-0.2-0.2-0.2-1.5-0.1-1.51.31.0
Bone: trabecular number1.11.84.0-0.40.61.91.91.5-1.71.6-2.0-1.1-1.3-1.4-1.4-1.3-1.4-1.31.5-1.5-1.6-1.6-0.0-0.40.10.10.3
Bone: trabecular spacing0.81.04.11.5-1.6-1.5-1.2-1.31.2-1.02.00.10.70.60.60.60.70.7-1.00.91.01.00.4-0.60.10.10.1
Bone: trabecular thickness0.60.71.8-0.90.6-0.5-0.3-0.60.5-0.6-0.80.30.91.01.01.00.90.8-0.40.81.01.01.01.30.8-1.0-1.1
Bone: trabecular tissue density2.43.49.2-2.72.7-1.1-1.7-0.61.5-1.8-0.52.42.02.02.02.02.12.0-1.72.01.91.9-0.43.0-0.1-1.0-1.7
Water consumed over 24 hours0.20.31.1-0.3-0.4-0.4-0.1-0.70.4-0.40.50.70.30.30.30.30.20.4-0.50.40.30.31.00.30.9-0.8-0.7
Number of responses in last shaping day0.20.21.00.8-1.0-0.8-0.6-0.60.5-0.40.6-0.30.30.30.30.40.30.2-0.40.10.20.20.3-0.5-0.50.40.3