Hub : Genes

Abhd18

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio XM_063282364.1 0.07 0.05 2.6e-04 0.02 0.02 0.02 0.02 1.4e-03 1.4e-03 2.2e-03 1.4e-03
2 Liver gene expression Abhd18 0.18 0.09 5.6e-17 0.11 0.09 0.1 0.1 3.5e-12 2.3e-10 1.2e-11 1.3e-11
3 Brain gene expression Abhd18 0.03 0.02 8.3e-03 0.03 0.02 0.01 0.02 2.2e-03 7.8e-03 4.0e-02 3.1e-03
4 Adipose alternative TSS NM_001025039.2 0.04 0.03 7.1e-04 0.03 0.02 0.01 0.02 7.4e-04 5.8e-03 8.9e-03 3.0e-03
5 Adipose alternative TSS XM_039102873.2 0.04 0.03 6.1e-04 0.03 0.02 0.02 0.02 7.4e-04 6.2e-03 4.9e-03 3.7e-03
6 Adipose alternative TSS NM_001025039.2 0.04 0.03 5.9e-04 0.03 0.02 0.01 0.02 6.2e-04 5.3e-03 1.1e-02 2.0e-03
7 Adipose alternative TSS XM_039102873.2 0.04 0.03 5.3e-04 0.03 0.02 0.02 0.02 6.1e-04 5.5e-03 6.1e-03 2.9e-03
8 PL gene expression Abhd18 0.03 0.03 3.6e-03 0.02 0.01 0.01 0.02 4.0e-03 1.7e-02 2.9e-02 6.1e-03
9 PL isoform ratio NM_001025039.2 0.05 0.03 1.1e-04 0.03 0.02 0.03 0.02 1.5e-04 1.0e-03 3.2e-04 1.1e-03
10 Adipose gene expression Abhd18 0.22 0.09 0.0e+00 0.17 0.18 0.17 0.18 4.8e-18 2.8e-19 1.7e-18 3.1e-19
11 IC gene expression Abhd18 0.13 0.08 2.1e-04 0.04 0.05 0.05 0.05 6.7e-03 2.8e-03 2.9e-03 2.9e-03
12 Liver isoform ratio XR_010063640.1 0.09 0.05 4.8e-09 0.07 0.07 0.06 0.07 2.5e-08 8.4e-08 1.1e-07 4.9e-08
13 Liver isoform ratio NM_001025039.2 0.04 0.03 3.3e-04 0.03 0.02 0.01 0.02 5.7e-04 6.2e-03 9.9e-03 2.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.00.00.1-0.2-0.2-0.1-0.00.0-0.00.00.00.0-0.00.0-0.10.2
Area under the delay curve0.30.30.60.20.50.60.6-0.60.6-0.60.30.20.80.7-0.70.6
BMI with tail2.58.718.24.3-3.4-3.3-3.03.0-3.03.0-3.2-3.1-2.4-2.41.5-1.6
BMI without tail1.64.98.62.9-2.5-2.5-2.22.2-2.22.2-2.4-2.3-2.0-1.91.4-1.5
Body weight2.912.927.65.3-4.0-3.9-3.83.8-3.83.8-3.9-3.6-2.9-2.91.9-1.9
Weight adjusted by age0.20.20.6-0.1-0.4-0.2-0.40.4-0.40.4-0.8-0.8-0.4-0.40.8-0.7
Bone surface0.81.41.91.0-1.3-1.2-1.11.1-1.11.1-1.0-1.0-1.4-1.41.3-1.3
Bone volume0.20.30.50.4-0.7-0.5-0.50.5-0.50.5-0.5-0.5-0.6-0.60.6-0.5
Breakpoint value in progressive ratio session0.20.30.90.5-0.3-0.4-0.40.4-0.40.4-0.4-0.6-0.6-0.60.8-1.0
Number of licking bursts2.13.47.02.6-1.9-2.1-2.02.0-2.02.0-2.1-2.1-1.2-1.21.0-0.9
Context. condit. distance diff. score0.50.61.0-1.00.71.00.7-0.70.7-0.71.01.00.60.6-0.60.7
Locomotion velocity, session 11.21.21.61.3-1.2-1.1-1.21.2-1.21.2-1.1-1.2-1.0-1.01.0-0.9
Locomotion distance, session 11.72.23.81.9-1.6-1.5-1.61.6-1.61.6-1.4-1.4-1.3-1.31.1-1.0
Locomotion velocity, session 21.61.92.51.5-1.5-1.6-1.61.6-1.61.6-1.5-1.6-0.9-0.80.5-0.5
Locomotion distance, session 21.62.33.81.9-1.6-1.7-1.71.7-1.71.7-1.5-1.6-1.2-1.20.8-0.9
Locomotion velocity, session 30.40.40.70.5-0.7-0.8-0.70.7-0.70.7-0.5-0.5-0.6-0.60.5-0.5
Locomotion distance, session 30.10.10.20.3-0.1-0.2-0.30.3-0.30.30.10.10.10.2-0.40.4
Stereotopy head waving bouts, day 30.50.60.90.3-0.8-0.8-0.70.7-0.70.7-0.8-1.0-0.8-0.80.9-1.0
Stereotopy head waving duration, day 30.81.01.80.4-1.0-0.9-0.80.8-0.80.8-1.0-1.1-1.2-1.11.3-1.3
Locomotion velocity, session 70.50.51.40.3-0.4-0.5-0.50.5-0.50.5-0.4-0.4-1.0-1.01.1-1.2
Locomotion distance, session 70.60.71.4-1.21.00.90.9-0.90.9-0.91.01.10.60.6-0.40.4
Stereotopy head waving bouts, day 73.74.25.82.1-2.2-2.3-2.22.2-2.22.2-2.2-2.4-1.7-1.71.4-1.6
Stereotopy head waving duration, day 73.74.56.22.1-2.2-2.3-2.22.2-2.22.2-2.3-2.5-1.9-1.81.7-1.8
Locomotion velocity, session 80.40.51.21.1-0.8-0.8-0.70.7-0.70.7-0.8-0.7-0.5-0.50.3-0.3
Locomotion distance, session 80.71.11.61.3-1.2-1.0-1.21.2-1.21.2-0.8-0.9-0.9-0.90.5-0.5
Degree of sensitization distance1.31.32.2-1.51.21.31.3-1.31.3-1.31.01.10.90.8-0.50.6
Degree of sensitization stereotypy3.03.24.32.0-1.9-2.0-2.02.0-2.02.0-1.9-2.1-1.4-1.41.1-1.2
Conditioned locomotion1.31.51.9-1.31.21.31.3-1.31.3-1.31.20.91.41.4-1.31.1
Cocaine response after cond. corrected1.11.41.6-0.91.11.21.3-1.31.3-1.31.21.11.21.2-1.11.2
Cocaine response after cond. not corrected1.31.52.0-1.21.21.31.4-1.41.4-1.41.31.21.01.0-0.90.9
Cocaine response before conditioning0.30.41.5-0.4-0.2-0.2-0.10.1-0.10.1-0.2-0.2-0.9-1.01.2-1.2
Saline control response0.91.12.20.7-0.9-0.9-0.90.9-0.90.9-0.9-1.0-1.3-1.31.4-1.5
Bone: connectivity density0.71.01.70.6-1.0-1.0-0.90.9-0.90.9-0.9-1.0-1.2-1.21.3-1.3
Bone: cortical apparent density0.00.10.2-0.50.20.20.1-0.10.1-0.10.1-0.00.30.4-0.20.2
Bone: cortical area2.13.34.32.1-2.0-2.1-2.02.0-2.02.0-1.7-1.5-1.7-1.71.2-1.1
Bone: cortical porosity0.20.30.8-0.50.10.20.3-0.30.3-0.30.30.3-0.6-0.60.9-0.9
Bone: cortical porosity0.20.30.9-0.40.10.20.2-0.20.2-0.20.30.3-0.7-0.71.0-0.9
Bone: cortical thickness0.00.10.10.1-0.2-0.3-0.30.3-0.30.30.10.2-0.1-0.1-0.20.3
Bone: cortical thickness1.01.21.71.3-1.1-1.3-1.31.3-1.31.3-1.1-1.1-0.7-0.70.5-0.4
Bone: cortical tissue density0.00.10.2-0.50.20.20.1-0.10.1-0.10.1-0.00.40.4-0.30.2
Condit. Reinf. active minus inactive responses0.40.50.91.0-0.6-0.7-0.70.7-0.70.7-0.7-0.5-0.7-0.70.6-0.5
Condit. Reinf. active-inactive response ratio0.00.00.20.5-0.1-0.2-0.10.1-0.10.1-0.1-0.1-0.2-0.20.2-0.1
Condit. Reinf. active responses2.22.74.12.0-1.6-1.6-1.61.6-1.61.6-1.7-1.5-1.7-1.71.6-1.5
Condit. Reinf. inactive responses4.65.66.12.5-2.3-2.1-2.42.4-2.42.4-2.4-2.5-2.3-2.32.4-2.4
Incentive salience index mean0.50.61.61.3-0.8-0.8-0.90.9-0.90.9-0.9-0.7-0.6-0.60.4-0.3
Condit. Reinf. lever presses0.81.12.21.5-1.2-1.1-1.21.2-1.21.2-1.2-1.1-0.6-0.60.3-0.4
Condit. Reinf. active minus inactive responses0.20.20.50.10.50.60.5-0.50.5-0.50.60.70.40.3-0.40.4
Condit. Reinf. active-inactive response ratio5.05.87.3-1.42.32.32.5-2.52.5-2.52.42.42.62.5-2.72.7
Condit. Reinf. active responses0.71.01.81.1-0.9-0.8-0.90.9-0.90.9-0.8-0.7-1.3-1.31.3-1.3
Condit. Reinf. inactive responses9.011.614.22.9-3.3-3.2-3.43.4-3.43.4-3.2-3.1-3.7-3.83.8-3.7
Condit. Reinf. lever presses0.00.10.40.6-0.1-0.2-0.10.1-0.10.10.0-0.1-0.3-0.30.1-0.2
Condit. Reinf. lever reinforcers received0.71.01.71.0-0.8-0.8-0.90.9-0.90.9-0.7-0.6-1.3-1.31.3-1.2
Conditioned reinforcement - actives0.00.00.2-0.4-0.1-0.4-0.10.1-0.10.1-0.1-0.1-0.1-0.00.0-0.0
Conditioned reinforcement - inactives1.52.25.8-2.41.71.61.7-1.71.7-1.71.61.40.60.6-0.10.1
Conditioned locomotion0.50.61.10.7-1.1-0.9-0.90.9-0.90.9-0.6-0.6-0.8-0.80.5-0.5
Patch foraging indifference point 0 sec2.13.86.22.5-2.1-2.2-2.02.0-2.02.0-2.4-2.1-1.5-1.51.5-1.4
Patch foraging indifference point AUC1.42.04.00.8-1.2-1.1-1.21.2-1.21.2-1.3-1.5-1.7-1.71.9-2.0
Delay disc. indifference point, 0s delay0.20.20.60.5-0.5-0.4-0.50.5-0.50.5-0.7-0.8-0.2-0.20.1-0.2
Delay disc. indifference point, 16s delay0.40.40.8-0.30.70.80.9-0.90.9-0.90.50.40.40.3-0.2-0.1
Delay disc. indifference point, 2s delay0.20.30.90.80.00.1-0.00.0-0.00.0-0.3-0.30.70.7-0.90.9
Delay disc. indifference point, 24s delay3.74.24.8-1.52.12.02.2-2.22.2-2.22.02.12.12.0-2.01.9
Delay disc. indifference point, 4s delay0.90.91.61.3-0.9-0.8-1.01.0-1.01.0-1.2-1.0-0.9-0.80.8-0.7
Delay disc. indifference point, 8s delay1.61.82.8-0.61.31.31.4-1.41.4-1.41.11.01.71.7-1.51.5
Indifference point function ln k1.01.83.4-0.61.21.21.2-1.21.2-1.21.11.21.61.6-1.81.9
Indifference point function log k1.01.83.4-0.61.21.21.2-1.21.2-1.21.11.21.61.6-1.81.9
Patch foraging total patch changes 0 sec1.73.25.02.2-1.8-2.1-1.81.8-1.81.8-2.2-2.0-1.4-1.41.4-1.4
Patch foraging total patch changes 12 sec1.52.02.91.0-1.4-1.3-1.31.3-1.31.3-1.5-1.6-1.5-1.51.6-1.7
Patch foraging total patch changes 18 sec2.03.14.31.6-1.6-1.6-1.61.6-1.61.6-1.9-2.1-1.7-1.71.9-2.1
Patch foraging total patch changes 24 sec3.25.56.12.4-2.5-2.3-2.32.3-2.32.3-2.5-2.4-2.4-2.42.4-2.4
Patch foraging total patch changes 6 sec3.75.66.62.1-2.3-2.5-2.22.2-2.22.2-2.5-2.5-2.5-2.52.5-2.6
Patch foraging time to switch 0 sec0.71.42.9-0.71.01.01.0-1.01.0-1.01.01.01.41.5-1.61.7
Patch foraging water rate 0 sec0.30.71.30.3-0.7-0.7-0.70.7-0.70.7-0.8-0.6-1.0-1.01.1-1.1
Patch foraging water rate 12 sec0.91.92.21.2-1.5-1.4-1.41.4-1.41.4-1.5-1.1-1.5-1.51.3-1.1
Patch foraging water rate 18 sec1.21.82.51.6-1.6-1.5-1.61.6-1.61.6-1.3-0.9-1.2-1.20.6-0.5
Patch foraging water rate 24 sec2.73.85.01.9-2.2-2.1-2.12.1-2.12.1-2.2-2.0-1.7-1.71.4-1.4
Patch foraging water rate 6 sec0.60.91.51.2-1.2-1.1-1.01.0-1.01.0-1.1-0.9-0.9-0.80.4-0.4
Seeking ratio, delayed vs. immediate footshock1.11.42.21.1-1.2-1.3-1.11.1-1.11.1-0.8-0.7-1.5-1.51.1-1.3
Distance traveled before self-admin0.60.81.91.4-0.9-0.9-0.90.9-0.90.9-0.7-0.8-0.9-0.90.6-0.7
Distance traveled after self-admin3.84.76.72.6-2.2-2.4-2.22.2-2.22.2-2.2-1.9-2.1-2.11.9-1.7
Extensor digitorum longus weight2.710.717.04.1-3.4-3.5-3.33.3-3.33.3-3.4-3.5-3.0-3.02.5-2.6
Bone: elastic displacement3.13.64.6-2.02.12.02.1-2.12.1-2.12.11.81.71.7-1.21.1
Bone: elastic work2.63.33.8-1.91.91.91.9-1.91.9-1.91.91.81.91.9-1.61.5
Bone: endosteal estimation3.06.610.53.2-2.8-2.6-2.72.7-2.72.7-2.7-2.4-2.5-2.41.9-1.8
Bone: endosteal perimeter1.63.55.02.2-2.0-1.8-1.81.8-1.81.8-2.0-1.8-1.9-1.91.6-1.6
Epididymis fat weight1.44.811.13.3-2.5-2.4-2.42.4-2.42.4-2.3-2.1-1.7-1.71.1-0.9
Delta time in closed arm before/after self-admin0.30.30.50.2-0.5-0.2-0.60.6-0.60.6-0.4-0.6-0.6-0.60.7-0.7
Delta time in open arm before/after self-admin2.42.42.8-1.41.61.41.5-1.51.5-1.51.51.61.71.7-1.71.6
Diff in mean of infusions in LGA sessions0.10.10.3-0.20.40.40.4-0.40.4-0.40.50.30.40.4-0.30.1
Delay discount exponential model param0.50.50.9-0.1-0.7-0.7-0.70.7-0.70.7-0.5-0.4-1.0-0.91.0-0.9
Extinction: sum of active levers before priming0.10.10.1-0.20.30.30.3-0.30.3-0.30.30.3-0.2-0.20.3-0.4
Active lever presses in extinction session 60.10.10.30.5-0.2-0.2-0.30.3-0.30.30.0-0.0-0.2-0.2-0.0-0.1
Bone: final force2.84.45.32.1-2.1-2.2-2.22.2-2.22.2-1.9-1.7-2.3-2.32.0-1.9
Bone: final moment2.74.45.32.1-2.1-2.2-2.22.2-2.22.2-1.9-1.7-2.3-2.32.0-1.9
Food consumed during 24 hour testing period0.10.10.40.60.00.10.2-0.20.2-0.2-0.10.00.50.5-0.50.6
Glucose0.10.10.50.30.0-0.00.0-0.00.0-0.00.00.10.40.4-0.70.7
Heart weight0.20.41.11.0-0.5-0.1-0.20.2-0.20.2-0.4-0.7-0.7-0.70.8-1.0
Delay discount hyperbolic model param0.40.51.0-0.3-0.6-0.6-0.60.6-0.60.6-0.3-0.3-0.9-0.91.0-1.0
Intermittent access intake day 1-15 change1.02.12.7-1.51.61.41.5-1.51.5-1.51.31.31.61.6-1.21.2
Intermittent access intake escalation0.81.72.1-1.31.41.31.4-1.41.4-1.41.21.21.41.4-1.11.0
Intermittent access intake escalation 20.10.10.2-0.20.50.30.3-0.30.3-0.30.20.30.50.5-0.20.2
Intermitt. access day 1 inactive lever presses0.10.41.6-0.6-0.00.4-0.20.2-0.20.2-0.4-0.1-0.6-0.71.2-1.3
Intermitt. access day 15 inactive lever presses1.63.25.7-2.42.02.12.0-2.02.0-2.01.81.81.31.3-0.70.7
Intermitt. access escalation Index1.11.53.2-1.81.41.61.2-1.21.2-1.21.51.30.70.7-0.40.4
Intermittent access day 1 total infusions0.20.30.8-0.90.60.50.6-0.60.6-0.60.60.40.40.4-0.20.1
Intermittent access day 15 total infusions0.81.21.9-1.41.31.01.2-1.21.2-1.21.21.01.01.0-0.70.5
Intermittent access terminal intake (last 3 days)0.20.30.8-0.90.70.30.6-0.60.6-0.60.60.40.40.4-0.1-0.1
Intermittent access total infusions0.10.10.3-0.40.2-0.10.1-0.10.1-0.10.1-0.2-0.2-0.20.4-0.6
Intermittent access day 1 locomotion1.01.31.60.8-1.1-1.2-1.11.1-1.11.1-1.1-1.0-1.3-1.21.2-1.1
Intermittent access day 15 total locomotion0.81.52.11.3-1.2-1.2-1.11.1-1.11.1-1.2-1.0-1.3-1.31.4-1.3
Intermittent access total locomotion1.82.12.91.2-1.4-1.4-1.41.4-1.41.4-1.5-1.5-1.6-1.61.7-1.7
Intermittent access standard deviation0.20.50.8-0.50.80.70.7-0.70.7-0.70.70.60.90.9-0.60.6
Left kidney weight0.10.31.71.3-0.6-0.6-0.30.3-0.30.3-0.5-0.60.10.1-0.60.3
Right kidney weight0.10.42.41.5-0.7-0.6-0.60.6-0.60.6-0.6-0.8-0.3-0.3-0.2-0.1
Cocaine induced anxiety0.30.41.1-0.00.71.10.7-0.70.7-0.70.60.70.50.5-0.10.3
Post-drug Anxiety0.00.00.20.20.20.40.2-0.20.2-0.20.00.20.10.10.2-0.1
Baseline Anxiety0.10.20.3-0.2-0.5-0.5-0.40.4-0.40.4-0.4-0.6-0.4-0.40.2-0.4
Tail length0.00.20.40.3-0.3-0.2-0.40.4-0.40.4-0.4-0.3-0.5-0.50.6-0.6
Length with tail0.41.94.42.1-1.4-1.3-1.51.5-1.51.5-1.5-1.1-1.3-1.31.0-0.8
Length without tail1.13.58.22.9-2.0-1.8-1.91.9-1.91.9-1.9-1.6-1.8-1.81.3-1.1
Times rat made contact with spout0.10.20.50.7-0.4-0.4-0.40.4-0.40.4-0.4-0.60.00.0-0.10.0
Lifetime Intake0.10.10.4-0.70.40.10.4-0.40.4-0.40.40.20.10.10.1-0.3
Liver weight, left0.00.10.20.30.00.10.2-0.20.2-0.20.10.10.40.4-0.40.4
Liver weight, right0.40.70.90.3-0.9-0.7-0.90.9-0.90.9-0.9-0.9-0.8-0.70.8-0.8
Locomotor activity0.81.32.6-0.91.21.51.1-1.11.1-1.11.61.41.00.9-0.90.9
Locomotor testing distance0.20.30.80.9-0.5-0.3-0.60.6-0.60.6-0.2-0.2-0.6-0.60.6-0.4
Locomotor testing rearing0.30.61.10.6-0.8-0.6-0.70.7-0.70.7-0.4-0.4-1.0-1.11.0-0.8
Locomotion in novel chamber1.21.62.91.7-1.6-1.5-1.41.4-1.41.4-1.1-1.1-1.1-1.10.4-0.5
Locomotion in novel chamber post-restriction0.30.51.00.5-0.7-0.6-0.30.3-0.30.3-1.0-1.0-0.7-0.71.0-1.0
Fecal boli incidents, locomotor time 11.72.52.9-1.11.51.61.7-1.71.7-1.71.61.31.71.7-1.61.5
Change in fecal boli incidents, locomotor task0.80.71.30.5-0.7-0.6-0.90.9-0.90.9-0.6-0.5-1.1-1.21.0-1.0
Time >=10cm from walls, locomotor time 10.50.61.2-0.60.70.60.6-0.60.6-0.61.01.10.70.7-0.70.9
Bouts of movement, locomotor time 12.02.33.4-1.91.81.81.5-1.51.5-1.51.81.81.11.1-0.70.9
Total resting periods, locomotor time 13.53.95.5-2.32.22.31.9-1.91.9-1.92.22.31.71.7-1.41.6
Rest time, locomotor task time 11.41.83.9-0.91.21.21.0-1.01.0-1.01.11.51.51.6-1.72.0
Distance moved, locomotor task time 12.74.04.81.8-2.0-2.1-1.91.9-1.91.9-2.0-2.2-2.0-2.02.0-2.2
Vertical activity count, locomotor time 12.86.78.42.8-2.6-2.9-2.82.8-2.82.8-2.6-2.9-2.3-2.31.9-2.3
Time >=10cm from walls, locomotor time 22.74.06.7-1.52.01.91.7-1.71.7-1.71.82.12.42.4-2.42.6
Bouts of movement, locomotor time 21.21.94.9-2.21.61.61.4-1.41.4-1.41.41.31.11.1-0.60.7
Total resting periods, locomotor time 20.91.54.0-2.01.41.41.3-1.31.3-1.31.41.30.90.9-0.50.6
Rest time, locomotor task time 20.40.50.8-0.80.70.70.9-0.90.9-0.90.70.90.40.4-0.40.6
Distance moved, locomotor task time 21.31.62.71.5-1.2-1.4-1.41.4-1.41.4-1.3-1.6-0.7-0.70.8-1.0
Vertical activity count, locomotor time 24.86.610.12.9-2.6-2.8-2.82.8-2.82.8-2.8-3.2-1.8-1.71.7-2.0
Light reinforcement 10.71.73.4-1.51.51.81.2-1.21.2-1.21.31.41.21.2-0.80.9
Light reinforcement 22.33.64.4-1.92.02.12.0-2.02.0-2.01.92.01.71.7-1.61.7
Bone: marrow area3.37.211.53.4-2.9-2.8-2.82.8-2.82.8-2.8-2.5-2.5-2.51.9-1.8
Bone: maximum diameter4.68.510.23.1-3.2-3.1-3.03.0-3.03.0-3.0-2.6-3.0-3.02.4-2.3
Bone: maximum force1.11.92.91.7-1.6-1.6-1.51.5-1.51.5-1.3-1.1-1.3-1.30.9-0.8
Bone: maximum moment1.01.82.81.7-1.5-1.5-1.51.5-1.51.5-1.2-1.1-1.3-1.30.9-0.9
Mean time between licks in bursts0.10.31.00.6-0.3-0.1-0.20.2-0.20.2-0.2-0.20.60.7-1.01.0
Mean num. licks in bursts1.21.93.9-2.01.41.61.5-1.51.5-1.51.61.60.90.9-0.70.7
Cd content in liver1.92.13.1-1.31.31.31.3-1.31.3-1.31.31.31.71.7-1.71.8
Co content in liver0.10.10.40.6-0.4-0.4-0.20.2-0.20.2-0.4-0.3-0.3-0.30.4-0.4
Cu content in liver0.50.62.10.4-0.3-0.5-0.40.4-0.40.4-0.3-0.4-1.2-1.21.3-1.5
Fe content in liver0.40.50.8-0.80.80.70.7-0.70.7-0.70.90.80.50.4-0.40.3
K content in liver0.20.20.7-0.50.20.20.1-0.10.1-0.10.10.1-0.5-0.50.8-0.8
Mg content in liver0.20.20.2-0.50.40.40.5-0.50.5-0.50.40.4-0.0-0.00.3-0.3
Mn content in liver1.31.52.2-1.41.21.21.5-1.51.5-1.51.11.20.90.9-0.60.7
Na content in liver1.71.83.60.8-1.1-1.1-1.11.1-1.11.1-1.2-1.2-1.6-1.61.9-1.9
Rb content in liver0.40.41.7-0.1-0.1-0.1-0.10.1-0.10.10.10.1-1.0-1.01.3-1.3
Se content in liver0.10.10.4-0.70.30.30.5-0.50.5-0.50.40.30.10.1-0.20.1
Sr content in liver0.30.30.9-0.20.30.20.3-0.30.3-0.30.30.20.70.7-0.90.9
Zn content in liver0.00.00.00.10.20.10.2-0.20.2-0.20.00.10.10.10.00.0
Bone: minimum diameter1.83.24.82.2-1.9-1.9-1.81.8-1.81.8-1.6-1.5-2.0-2.01.6-1.5
Time in familiar zone, hab. session 10.20.20.40.4-0.4-0.6-0.40.4-0.40.4-0.4-0.5-0.4-0.40.4-0.5
Time in novel zone, hab. session 10.20.20.5-0.2-0.30.1-0.30.3-0.30.3-0.2-0.2-0.5-0.50.7-0.6
Total zone transitions, hab. session 10.20.30.80.9-0.6-0.6-0.60.6-0.60.6-0.4-0.4-0.5-0.50.3-0.3
Total locomotion distance, hab. session 10.60.81.10.8-0.8-0.9-0.90.9-0.90.9-0.9-0.8-1.0-1.01.0-1.0
Locomotion velocity, hab. session 10.30.50.60.7-0.6-0.6-0.70.7-0.70.7-0.7-0.6-0.7-0.80.7-0.7
Time in familiar zone, hab. session 21.21.23.0-1.71.11.01.2-1.21.2-1.21.11.00.90.9-0.70.6
Time in novel zone, hab. session 22.12.23.81.9-1.5-1.3-1.51.5-1.51.5-1.4-1.3-1.4-1.51.3-1.2
Total zone transitions, hab. session 21.21.62.41.5-1.4-1.4-1.41.4-1.41.4-1.2-1.2-1.1-1.10.8-0.8
Total locomotion distance, hab. session 20.30.40.60.8-0.6-0.7-0.60.6-0.60.6-0.7-0.6-0.5-0.50.4-0.4
Locomotion velocity, hab. session 20.40.50.80.9-0.7-0.8-0.70.7-0.70.7-0.8-0.7-0.6-0.60.5-0.5
Novel to familiar place preference ratio0.10.20.20.3-0.4-0.2-0.40.4-0.40.4-0.4-0.2-0.5-0.50.5-0.5
Novelty place preference0.20.20.40.2-0.5-0.3-0.50.5-0.50.5-0.4-0.3-0.6-0.60.7-0.6
Time in novel zone, NPP test0.70.71.10.5-0.8-0.6-0.80.8-0.80.8-0.7-0.6-1.0-1.01.1-1.0
Total zone transitions, NPP test0.10.20.30.5-0.4-0.5-0.50.5-0.50.5-0.3-0.2-0.5-0.50.3-0.3
Total locomotion distance, NPP test0.00.00.10.1-0.2-0.2-0.20.2-0.20.2-0.1-0.0-0.3-0.30.3-0.2
Locomotion velocity, NPP test0.00.00.1-0.20.10.0-0.00.0-0.00.00.10.2-0.0-0.0-0.10.1
Intraocular pressure3.04.311.0-1.01.71.71.3-1.31.3-1.31.82.02.62.7-3.13.3
Delta distance traveled before/after self-admin1.51.62.51.1-1.4-1.6-1.41.4-1.41.4-1.3-1.0-1.2-1.21.1-0.9
Delta ambulatory time before/after self-admin0.70.91.20.8-1.0-1.1-1.01.0-1.01.0-1.0-0.8-0.9-0.91.0-0.8
Parametrial fat weight0.10.21.01.0-0.5-0.5-0.30.3-0.30.3-0.3-0.3-0.1-0.1-0.30.3
Pavlov. Cond. lever latency0.50.61.7-1.30.91.00.7-0.70.7-0.71.00.8-0.1-0.20.6-0.6
Pavlov. Cond. magazine entry latency1.31.73.41.8-1.4-1.6-1.31.3-1.31.3-1.6-1.5-0.9-0.90.7-0.6
Pavlov. Cond. change in total contacts0.60.61.31.2-0.8-0.9-0.80.8-0.80.8-1.1-1.0-0.1-0.1-0.10.2
Pavlov. Cond. index score1.82.24.62.1-1.8-1.9-1.61.6-1.61.6-1.8-1.7-0.8-0.70.3-0.2
Pavlov. Cond. latency score1.51.93.82.0-1.6-1.7-1.51.5-1.51.5-1.7-1.6-0.7-0.70.2-0.2
Pavlov. Cond. lever contacts0.70.92.51.6-1.1-1.1-0.90.9-0.90.9-1.2-1.0-0.00.0-0.50.6
Pavlov. Cond. magazine entry number3.74.77.5-2.72.42.52.3-2.32.3-2.32.52.41.61.5-1.11.1
Pavlov. Cond. intertrial magazine entries4.15.06.4-2.32.52.22.4-2.42.4-2.42.32.52.02.0-1.71.9
Pavlov. Cond. lever-magazine prob. diff.1.41.83.81.9-1.6-1.7-1.41.4-1.41.4-1.6-1.5-0.6-0.60.1-0.0
Pavlov. Cond. response bias2.53.16.52.5-2.0-2.1-1.91.9-1.91.9-2.1-2.0-0.9-0.90.4-0.3
Pavlov. Cond. lever latency2.33.14.0-1.81.71.71.7-1.71.7-1.71.41.62.02.0-1.92.0
Pavlov. Cond. magazine entry latency2.12.63.51.9-1.6-1.5-1.61.6-1.61.6-1.5-1.5-1.6-1.61.6-1.5
Pavlov. Cond. change in total contacts1.93.14.71.8-1.6-1.5-1.61.6-1.61.6-1.2-1.3-2.1-2.22.1-2.2
Pavlov. Cond. index score4.15.57.22.7-2.3-2.3-2.32.3-2.32.3-2.1-2.2-2.5-2.52.4-2.4
Pavlov. Cond. latency score3.34.36.12.5-2.0-2.0-2.12.1-2.12.1-1.9-1.9-2.2-2.22.0-2.0
Pavlov. Cond. lever contacts3.14.35.02.1-2.0-2.0-2.02.0-2.02.0-1.8-1.9-2.2-2.22.1-2.2
Pavlov. Cond. magazine entry number5.06.17.6-2.82.42.32.5-2.52.5-2.52.22.32.62.6-2.52.5
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.40.30.20.3-0.30.3-0.30.30.20.50.5-0.50.5
Pavlov. Cond. lever-magazine prob. diff.3.95.26.62.6-2.2-2.2-2.32.3-2.32.3-2.0-2.1-2.4-2.42.3-2.3
Pavlov. Cond. response bias3.85.16.62.2-2.1-2.1-2.22.2-2.22.2-1.9-2.0-2.5-2.62.5-2.5
Time in closed arm before self-admin0.10.10.2-0.50.30.10.3-0.30.3-0.3-0.00.00.40.4-0.10.1
Time in closed arm after self-admin0.10.10.1-0.1-0.2-0.2-0.20.2-0.20.2-0.3-0.3-0.2-0.20.3-0.3
Time in open arm before self-admin2.93.14.71.9-1.7-1.3-1.61.6-1.61.6-1.6-1.9-1.9-2.02.0-2.2
Time in open arm after self-admin0.40.40.7-0.20.60.70.7-0.70.7-0.70.60.50.80.8-0.80.7
Bone: periosteal estimation3.36.910.43.2-2.9-2.8-2.82.8-2.82.8-2.6-2.3-2.5-2.51.8-1.7
Bone: periosteal perimeter2.54.35.41.9-2.1-2.0-2.12.1-2.12.1-2.0-1.7-2.3-2.32.1-2.0
Bone: post-yield work0.40.51.81.2-0.3-0.2-0.10.1-0.10.1-0.4-0.40.90.9-1.31.3
Progressive ratio test 1 active lever presses0.70.81.50.4-0.8-1.0-0.90.9-0.90.9-0.8-0.7-1.0-1.11.2-1.1
Progressive ratio test 1 breakpoint0.91.11.90.5-0.9-1.2-1.01.0-1.01.0-0.9-0.8-1.2-1.21.4-1.3
Progressive ratio test 1 inactive lever presses0.40.52.2-0.4-0.3-0.2-0.40.4-0.40.4-0.4-0.6-0.8-0.81.3-1.5
Progressive ratio test 2 active lever presses0.10.10.20.2-0.2-0.4-0.20.2-0.20.2-0.3-0.2-0.2-0.20.3-0.3
Progressive ratio test 2 breakpoint0.10.10.30.2-0.3-0.5-0.30.3-0.30.3-0.3-0.3-0.3-0.30.4-0.3
Progressive ratio test 2 inactive lever presses1.42.33.5-1.91.71.71.6-1.61.6-1.61.51.51.31.3-0.80.9
Incentive Sensitization - Responses0.10.10.30.00.30.10.3-0.30.3-0.30.30.30.50.5-0.50.5
Incentive Sensitization - Breakpoint0.10.20.3-0.00.40.20.4-0.40.4-0.40.40.40.50.5-0.60.5
Sum of active levers in priming session hrs 5-60.10.10.20.10.20.10.3-0.30.3-0.30.30.5-0.0-0.1-0.1-0.0
Progressive ratio0.10.20.4-0.50.60.40.6-0.60.6-0.60.30.30.20.2-0.0-0.2
Food seeking constrained by brief footshock0.50.61.91.4-0.9-0.9-0.90.9-0.90.9-0.9-0.7-0.2-0.1-0.30.5
Seeking ratio, punishment vs. effort0.40.61.31.2-0.9-0.9-0.90.9-0.90.9-0.7-0.6-0.3-0.3-0.00.3
Retroperitoneal fat weight1.35.412.83.6-2.7-2.7-2.32.3-2.32.3-2.4-2.4-1.8-1.81.1-1.1
Reaction time number correct0.50.91.40.3-1.1-1.1-1.11.1-1.11.1-0.9-0.6-1.2-1.10.8-0.7
Reaction time mean minus median0.20.51.40.80.50.40.5-0.50.5-0.50.80.50.80.8-1.20.8
Reaction time mean minus median AUC0.10.21.61.3-0.1-0.3-0.20.2-0.20.20.1-0.30.40.4-0.80.4
Reaction time num false alarms1.11.52.1-1.11.51.21.3-1.31.3-1.31.21.11.31.3-1.01.0
Reaction time num false alarms AUC0.91.52.0-1.31.41.21.2-1.21.2-1.21.21.11.41.4-1.11.1
Reaction time trials correct on left0.50.91.40.3-1.1-1.1-1.11.1-1.11.1-0.9-0.6-1.2-1.10.8-0.7
Reaction time trials on left0.40.81.20.3-1.0-1.0-1.01.0-1.01.0-0.8-0.5-1.1-1.10.7-0.6
Reaction time mean0.30.41.20.70.40.50.4-0.40.4-0.40.90.50.70.7-1.10.8
Reaction time mean AUC0.20.40.90.60.50.50.5-0.50.5-0.50.90.60.70.6-0.90.7
Median of all reaction times0.30.40.90.40.40.60.5-0.50.5-0.50.90.60.70.7-1.00.7
Reaction time omissions3.65.26.6-1.12.52.32.3-2.32.3-2.32.62.42.32.3-2.32.2
Reaction time false alarm rate1.21.72.5-1.11.61.41.4-1.41.4-1.41.21.01.51.5-1.11.0
Reaction time premature initiation rate4.66.411.9-3.42.92.72.9-2.92.9-2.92.62.51.91.8-1.11.3
Reaction time premature initiations1.52.77.2-2.71.81.61.8-1.81.8-1.81.71.80.90.9-0.60.7
Std. dev. reaction times0.20.31.71.30.1-0.00.1-0.10.1-0.10.60.20.50.5-1.10.7
Reaction time trials completed0.40.81.20.3-1.0-1.0-1.01.0-1.01.0-0.8-0.5-1.1-1.10.7-0.6
Reaction time trials AUC0.40.81.30.3-1.0-1.0-1.01.0-1.01.0-0.8-0.5-1.1-1.10.8-0.7
Run reversals in cocaine runway, females4.14.15.71.4-1.8-1.8-2.02.0-2.02.0-2.1-2.0-2.2-2.22.4-2.3
Run reversals in cocaine runway, males1.51.52.71.1-1.1-1.1-1.11.1-1.11.1-1.2-1.4-1.2-1.21.6-1.6
Latency to leave start box in cocaine runway0.91.01.5-1.21.11.11.2-1.21.2-1.21.01.20.80.8-0.50.4
Latency to leave start box in cocaine runway, F0.30.40.7-0.80.50.60.6-0.60.6-0.60.50.70.60.6-0.40.3
Latency to leave start box in cocaine runway, M1.00.91.4-0.81.11.11.2-1.21.2-1.21.01.10.60.6-0.40.3
Std. dev. time between licks in bursts0.10.10.30.4-0.00.1-0.20.2-0.20.20.00.10.30.3-0.40.5
Total sessions with >9 infusions0.70.81.4-1.21.00.81.0-1.01.0-1.01.20.90.70.7-0.60.4
Short access day 1 total inactive lever presses0.10.10.8-0.90.10.30.1-0.10.1-0.1-0.10.1-0.2-0.20.5-0.5
Short access day 10 total inactive lever presses0.10.30.9-0.0-0.40.0-0.50.5-0.50.5-0.7-0.6-0.5-0.50.9-0.9
Short access day 1 total infusions0.50.61.8-1.30.90.90.9-0.90.9-0.90.90.70.40.40.0-0.1
Short access day 10 total infusions0.10.20.5-0.70.50.20.5-0.50.5-0.50.50.3-0.0-0.00.2-0.3
Short access total infusions0.30.41.2-1.10.70.50.7-0.70.7-0.70.90.60.40.4-0.30.1
Short access day 1 locomotion0.50.61.40.4-0.6-0.5-0.70.7-0.70.7-0.7-0.7-0.9-0.91.2-1.2
Short access day 10 total locomotion0.61.01.81.4-1.1-0.9-1.11.1-1.11.1-1.2-1.1-0.7-0.70.7-0.7
Short access total locomotion0.40.50.60.7-0.6-0.8-0.70.7-0.70.7-0.6-0.7-0.7-0.70.6-0.7
One hour access (0.3 mA shock)1.11.32.20.8-1.0-1.5-1.11.1-1.11.1-1.1-1.1-1.2-1.21.3-1.2
Compulsive drug intake5.05.96.82.6-2.6-2.6-2.42.4-2.42.4-2.5-2.4-2.4-2.42.2-2.1
One hour access (shock baseline)0.40.71.2-1.10.90.60.9-0.90.9-0.90.80.80.80.8-0.50.5
Social response proportion5.46.19.6-2.02.32.12.3-2.32.3-2.32.42.22.92.9-3.12.9
Social responses0.81.01.30.9-1.0-1.1-1.11.1-1.11.1-1.1-1.2-0.7-0.70.7-0.8
Social time3.44.75.9-2.42.22.32.2-2.22.2-2.22.21.82.32.3-2.11.8
Soleus weight2.57.38.72.7-2.9-2.8-2.72.7-2.72.7-2.8-2.6-2.7-2.72.4-2.3
Bone: stiffness2.64.25.12.3-2.2-2.3-2.22.2-2.22.2-2.1-1.9-2.0-2.01.5-1.5
Tibialis anterior weight5.819.628.15.3-4.7-4.9-4.64.6-4.64.6-4.6-4.6-4.1-4.03.4-3.4
Time to tail flick, vehicle, before self-admin0.30.30.50.5-0.6-0.6-0.50.5-0.50.5-0.7-0.6-0.4-0.40.5-0.4
Time to tail flick, vehicle, after self-admin3.03.94.6-1.72.02.11.9-1.91.9-1.91.91.82.12.1-2.12.0
Time to tail flick, test, before self-admin0.30.30.40.10.60.50.6-0.60.6-0.60.50.40.50.5-0.40.4
Time to tail flick, test, after self-admin1.71.82.81.4-1.4-1.4-1.31.3-1.31.3-1.7-1.7-1.0-1.01.1-1.1
Delta time to tail flick, vehicle, before/after SA4.64.45.9-1.92.12.11.9-1.91.9-1.92.12.02.22.3-2.42.3
Delta time to tail flick, test, before/after SA1.41.42.21.0-1.3-1.2-1.31.3-1.31.3-1.5-1.4-0.9-0.90.9-0.9
Tibia length0.20.40.80.9-0.8-0.7-0.80.8-0.80.8-0.6-0.4-0.3-0.3-0.10.2
Ambulatory time before self-admin0.81.21.71.3-1.0-1.1-1.11.1-1.11.1-1.0-1.1-1.2-1.21.0-1.1
Ambulatory time after self-admin3.23.84.31.9-1.9-2.0-2.02.0-2.02.0-1.8-1.6-2.1-2.11.9-1.8
Bone: tissue strength1.31.32.2-1.51.41.41.3-1.31.3-1.31.31.30.50.50.0-0.0
Total heroin consumption0.10.20.50.2-0.2-0.2-0.30.3-0.30.3-0.2-0.1-0.6-0.60.6-0.7
Bone: trabecular number0.30.50.80.2-0.8-0.6-0.70.7-0.70.7-0.6-0.7-0.8-0.80.9-0.8
Bone: trabecular spacing0.20.20.4-0.50.60.50.4-0.40.4-0.40.60.60.30.3-0.30.3
Bone: trabecular thickness0.00.00.3-0.0-0.2-0.1-0.10.1-0.10.1-0.00.00.20.2-0.30.5
Bone: trabecular tissue density0.40.61.7-0.50.50.60.3-0.30.3-0.30.60.51.01.0-1.31.3
Water consumed over 24 hours0.60.83.01.7-1.0-1.0-0.90.9-0.90.9-1.0-0.8-0.4-0.30.00.2
Number of responses in last shaping day0.00.10.2-0.40.20.10.2-0.20.2-0.2-0.0-0.10.10.10.3-0.3