Hub : Genes

Ccdc51

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Ccdc51 0.16 0.08 0.0e+00 0.18 0.17 0.18 0.18 5.9e-17 1.1e-15 7.6e-17 1.7e-16
2 Adipose mRNA stability Ccdc51 0.04 0.03 8.9e-06 0.04 0.04 0.04 0.03 7.8e-05 5.2e-05 4.3e-05 9.8e-05
3 Liver mRNA stability Ccdc51 0.15 0.08 0.0e+00 0.2 0.2 0.2 0.2 4.4e-22 2.8e-21 3.1e-21 2.3e-21
4 Liver gene expression Ccdc51 0.07 0.04 1.2e-10 0.1 0.09 0.09 0.09 8.2e-11 3.2e-10 2.0e-10 1.5e-10
5 NAcc mRNA stability Ccdc51 0.04 0.03 9.8e-06 0.04 0.04 0.03 0.04 2.4e-05 1.3e-05 8.7e-05 2.7e-05
6 BLA mRNA stability Ccdc51 0.1 0.07 4.1e-05 0.09 0.07 0.06 0.08 2.6e-05 1.5e-04 3.0e-04 2.9e-05
7 NAcc gene expression Ccdc51 0.03 0.02 1.3e-03 0.03 0.02 0.03 0.02 5.5e-04 9.5e-04 6.6e-04 8.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.00.00.10.0-0.1-0.2-0.2-0.40.1-0.1
Area under the delay curve2.12.23.01.31.51.51.5-1.71.31.5
BMI with tail0.31.12.1-1.5-1.1-0.7-0.81.2-1.0-0.8
BMI without tail1.53.14.7-2.2-1.8-1.4-1.61.8-1.8-1.7
Body weight6.025.329.5-5.3-5.1-4.8-5.05.4-5.0-4.5
Weight adjusted by age0.50.51.2-0.8-0.5-0.5-0.51.1-0.8-0.8
Bone surface0.10.10.20.30.40.40.4-0.40.50.4
Bone volume0.00.10.10.20.20.20.2-0.30.40.2
Breakpoint value in progressive ratio session0.10.10.3-0.4-0.3-0.3-0.20.1-0.5-0.5
Number of licking bursts0.20.20.30.50.60.60.50.00.50.4
Context. condit. distance diff. score0.00.00.0-0.10.00.00.00.1-0.0-0.1
Locomotion velocity, session 10.10.10.10.10.20.30.2-0.40.20.3
Locomotion distance, session 10.81.01.9-1.4-1.1-0.9-0.90.7-1.0-0.9
Locomotion velocity, session 20.20.30.40.40.40.70.6-0.40.60.6
Locomotion distance, session 20.10.10.3-0.20.00.30.3-0.50.20.3
Locomotion velocity, session 30.10.10.4-0.7-0.2-0.1-0.1-0.2-0.20.1
Locomotion distance, session 31.41.52.10.81.21.31.3-1.51.21.4
Stereotopy head waving bouts, day 30.10.10.6-0.1-0.2-0.2-0.20.8-0.2-0.2
Stereotopy head waving duration, day 30.30.30.6-0.3-0.5-0.6-0.60.8-0.5-0.6
Locomotion velocity, session 70.00.10.1-0.3-0.1-0.2-0.2-0.3-0.3-0.1
Locomotion distance, session 71.21.52.31.11.21.21.2-1.51.11.3
Stereotopy head waving bouts, day 70.00.00.10.30.10.00.1-0.30.2-0.0
Stereotopy head waving duration, day 70.30.40.5-0.5-0.7-0.7-0.60.5-0.5-0.7
Locomotion velocity, session 80.20.20.7-0.8-0.5-0.3-0.30.1-0.4-0.3
Locomotion distance, session 80.10.20.8-0.9-0.5-0.2-0.3-0.1-0.4-0.4
Degree of sensitization distance1.21.21.5-0.8-1.1-1.1-1.21.1-1.1-1.2
Degree of sensitization stereotypy0.10.10.1-0.2-0.3-0.3-0.3-0.1-0.2-0.3
Conditioned locomotion3.03.54.42.01.91.81.8-2.11.81.7
Cocaine response after cond. corrected0.40.41.3-0.4-0.5-0.5-0.51.1-0.6-0.7
Cocaine response after cond. not corrected2.02.33.5-1.4-1.4-1.4-1.31.9-1.5-1.5
Cocaine response before conditioning1.01.21.9-1.4-1.2-1.2-1.10.8-1.2-0.9
Saline control response1.41.82.4-1.3-1.3-1.5-1.50.8-1.5-1.4
Bone: connectivity density0.20.41.20.60.50.40.4-1.10.60.4
Bone: cortical apparent density0.20.30.50.50.50.40.5-0.70.50.5
Bone: cortical area0.10.20.30.50.40.50.50.20.50.5
Bone: cortical porosity0.10.10.50.30.2-0.00.1-0.70.10.1
Bone: cortical porosity0.20.31.00.50.40.20.3-1.00.30.3
Bone: cortical thickness0.10.21.2-0.2-0.3-0.3-0.31.1-0.2-0.2
Bone: cortical thickness0.00.00.00.20.00.00.00.10.10.1
Bone: cortical tissue density0.20.30.50.50.50.40.5-0.70.50.5
Condit. Reinf. active minus inactive responses0.10.10.2-0.1-0.3-0.4-0.40.5-0.3-0.0
Condit. Reinf. active-inactive response ratio0.30.30.7-0.3-0.5-0.6-0.60.9-0.6-0.2
Condit. Reinf. active responses0.00.00.10.30.10.10.10.10.20.1
Condit. Reinf. inactive responses0.60.71.00.80.80.90.9-0.91.00.5
Incentive salience index mean0.00.10.10.20.20.30.2-0.10.20.4
Condit. Reinf. lever presses1.41.92.21.21.41.51.4-1.31.41.3
Condit. Reinf. active minus inactive responses1.92.32.8-1.7-1.5-1.5-1.61.5-1.6-1.1
Condit. Reinf. active-inactive response ratio1.61.62.2-1.5-1.2-1.1-1.21.4-1.4-1.0
Condit. Reinf. active responses1.82.52.9-1.7-1.5-1.6-1.71.6-1.7-1.2
Condit. Reinf. inactive responses0.00.00.00.20.0-0.1-0.0-0.1-0.00.1
Condit. Reinf. lever presses2.23.03.9-2.0-1.8-1.7-1.81.8-1.7-1.3
Condit. Reinf. lever reinforcers received2.02.73.2-1.7-1.6-1.7-1.71.7-1.8-1.3
Conditioned reinforcement - actives0.40.40.50.50.70.60.6-0.70.50.6
Conditioned reinforcement - inactives1.11.21.71.21.11.21.1-0.51.21.3
Conditioned locomotion0.30.40.90.40.60.60.5-0.90.40.5
Patch foraging indifference point 0 sec1.21.92.6-1.6-1.3-1.3-1.31.0-1.5-1.4
Patch foraging indifference point AUC0.10.10.1-0.2-0.3-0.2-0.3-0.3-0.3-0.3
Delay disc. indifference point, 0s delay0.00.00.10.20.10.10.2-0.30.20.1
Delay disc. indifference point, 16s delay1.01.01.40.91.01.01.0-1.20.91.0
Delay disc. indifference point, 2s delay0.20.30.40.40.50.60.6-0.60.30.4
Delay disc. indifference point, 24s delay0.90.91.30.80.90.90.9-1.10.91.1
Delay disc. indifference point, 4s delay1.81.92.41.21.51.61.6-1.41.21.2
Delay disc. indifference point, 8s delay2.22.23.11.31.51.51.5-1.71.31.5
Indifference point function ln k0.30.41.10.50.40.50.6-0.50.81.0
Indifference point function log k0.30.41.10.50.40.50.6-0.50.81.0
Patch foraging total patch changes 0 sec1.32.22.6-1.6-1.5-1.5-1.51.2-1.6-1.4
Patch foraging total patch changes 12 sec1.11.41.6-1.1-1.2-1.2-1.21.0-1.2-1.2
Patch foraging total patch changes 18 sec2.12.83.7-1.4-1.7-1.7-1.91.2-1.9-1.7
Patch foraging total patch changes 24 sec2.83.43.8-1.8-2.0-1.9-1.91.8-1.9-1.6
Patch foraging total patch changes 6 sec0.20.30.6-0.8-0.5-0.6-0.6-0.0-0.6-0.5
Patch foraging time to switch 0 sec0.10.10.30.50.50.50.30.00.30.2
Patch foraging water rate 0 sec0.10.20.4-0.5-0.5-0.6-0.50.5-0.4-0.4
Patch foraging water rate 12 sec0.10.20.3-0.5-0.6-0.4-0.40.5-0.4-0.4
Patch foraging water rate 18 sec0.00.00.1-0.1-0.00.10.20.40.20.1
Patch foraging water rate 24 sec0.71.01.1-1.0-1.0-1.0-1.01.1-0.9-1.0
Patch foraging water rate 6 sec0.20.30.5-0.4-0.7-0.7-0.60.4-0.4-0.5
Seeking ratio, delayed vs. immediate footshock2.73.13.71.61.81.91.9-1.91.71.4
Distance traveled before self-admin0.10.10.20.30.20.00.10.20.20.4
Distance traveled after self-admin0.30.40.50.60.70.60.6-0.40.50.7
Extensor digitorum longus weight0.10.50.80.60.90.90.7-0.40.60.8
Bone: elastic displacement0.10.10.3-0.0-0.2-0.3-0.30.5-0.1-0.0
Bone: elastic work0.40.51.1-0.6-0.7-0.7-0.61.0-0.5-0.5
Bone: endosteal estimation0.00.10.1-0.2-0.2-0.3-0.3-0.1-0.3-0.3
Bone: endosteal perimeter1.02.22.31.41.41.51.5-1.51.51.5
Epididymis fat weight0.20.50.7-0.8-0.7-0.7-0.80.8-0.7-0.4
Delta time in closed arm before/after self-admin0.30.30.70.80.30.30.4-0.70.70.4
Delta time in open arm before/after self-admin0.10.10.2-0.5-0.3-0.3-0.40.3-0.4-0.4
Diff in mean of infusions in LGA sessions0.10.10.5-0.2-0.00.10.10.7-0.2-0.3
Delay discount exponential model param2.42.53.3-1.4-1.6-1.7-1.71.8-1.4-1.6
Extinction: sum of active levers before priming0.00.00.1-0.30.0-0.00.1-0.2-0.2-0.2
Active lever presses in extinction session 60.20.20.5-0.6-0.4-0.6-0.50.1-0.7-0.2
Bone: final force1.01.62.8-1.3-1.3-1.2-1.21.7-1.1-1.2
Bone: final moment1.32.13.6-1.4-1.4-1.3-1.31.9-1.3-1.3
Food consumed during 24 hour testing period1.51.82.0-1.3-1.4-1.3-1.41.4-1.3-1.1
Glucose0.30.40.5-0.7-0.7-0.6-0.70.2-0.6-0.7
Heart weight2.94.06.2-1.7-2.1-2.1-2.02.5-1.7-1.9
Delay discount hyperbolic model param2.42.53.3-1.4-1.6-1.7-1.71.8-1.4-1.6
Intermittent access intake day 1-15 change0.60.61.10.80.70.80.7-0.20.81.0
Intermittent access intake escalation0.60.61.10.80.80.80.8-0.30.81.0
Intermittent access intake escalation 20.10.10.30.2-0.0-0.0-0.10.50.20.5
Intermitt. access day 1 inactive lever presses0.00.00.0-0.1-0.10.0-0.00.1-0.1-0.1
Intermitt. access day 15 inactive lever presses0.60.61.00.70.91.00.9-0.30.70.7
Intermitt. access escalation Index0.00.00.1-0.1-0.0-0.00.1-0.2-0.1-0.2
Intermittent access day 1 total infusions0.00.00.1-0.10.20.20.2-0.2-0.1-0.1
Intermittent access day 15 total infusions0.40.40.70.50.70.80.7-0.40.50.7
Intermittent access terminal intake (last 3 days)0.20.20.30.20.50.60.5-0.30.20.4
Intermittent access total infusions0.40.50.70.50.80.80.8-0.60.50.7
Intermittent access day 1 locomotion0.10.10.20.10.50.50.5-0.50.10.2
Intermittent access day 15 total locomotion1.01.11.71.00.90.90.9-1.31.01.1
Intermittent access total locomotion1.11.32.11.01.11.11.1-1.41.01.2
Intermittent access standard deviation0.20.21.0-0.4-0.3-0.2-0.31.0-0.40.1
Left kidney weight0.72.13.8-2.0-1.6-1.3-1.41.0-1.3-1.2
Right kidney weight0.20.51.3-1.1-0.8-0.7-0.60.2-0.6-0.5
Cocaine induced anxiety0.20.20.50.00.60.70.70.00.00.1
Post-drug Anxiety0.10.10.20.10.40.40.4-0.00.1-0.0
Baseline Anxiety0.70.71.01.00.70.60.6-0.91.00.9
Tail length6.619.821.2-4.5-4.5-4.4-4.64.4-4.3-4.5
Length with tail9.033.134.8-5.7-5.8-5.8-5.95.9-5.6-5.5
Length without tail6.414.116.1-3.7-3.8-3.9-3.84.0-3.7-3.4
Times rat made contact with spout0.80.91.1-0.9-0.9-1.0-1.01.1-0.9-0.9
Lifetime Intake0.40.50.50.60.70.70.7-0.70.60.7
Liver weight, left0.10.10.3-0.3-0.2-0.4-0.3-0.2-0.3-0.5
Liver weight, right1.32.23.1-1.8-1.5-1.5-1.41.0-1.5-1.6
Locomotor activity5.38.59.0-2.9-2.9-2.9-2.82.9-3.0-3.0
Locomotor testing distance4.47.37.9-2.8-2.7-2.7-2.62.7-2.8-2.7
Locomotor testing rearing0.00.10.1-0.1-0.2-0.2-0.10.3-0.4-0.4
Locomotion in novel chamber0.10.10.20.40.20.20.4-0.00.40.4
Locomotion in novel chamber post-restriction0.50.71.1-0.6-1.0-1.0-1.00.6-0.6-0.6
Fecal boli incidents, locomotor time 10.50.61.0-0.8-0.7-0.6-0.60.9-0.6-1.0
Change in fecal boli incidents, locomotor task0.00.00.10.1-0.1-0.1-0.1-0.2-0.10.2
Time >=10cm from walls, locomotor time 10.40.40.90.70.30.30.2-0.80.61.0
Bouts of movement, locomotor time 10.10.10.2-0.2-0.2-0.1-0.10.3-0.2-0.5
Total resting periods, locomotor time 10.00.00.2-0.1-0.1-0.0-0.10.2-0.1-0.4
Rest time, locomotor task time 10.60.70.90.90.80.80.8-0.91.00.4
Distance moved, locomotor task time 11.71.92.4-1.3-1.4-1.5-1.51.5-1.3-0.9
Vertical activity count, locomotor time 11.11.11.2-0.9-1.1-1.1-1.11.1-1.0-1.1
Time >=10cm from walls, locomotor time 21.31.41.7-1.0-1.3-1.3-1.31.1-1.1-0.9
Bouts of movement, locomotor time 20.00.00.00.00.20.20.10.10.00.2
Total resting periods, locomotor time 20.20.20.30.30.50.50.4-0.30.30.4
Rest time, locomotor task time 20.10.10.10.20.30.40.4-0.40.3-0.3
Distance moved, locomotor task time 21.21.31.9-1.0-1.3-1.4-1.41.3-1.0-0.5
Vertical activity count, locomotor time 20.10.10.2-0.2-0.4-0.5-0.50.4-0.20.0
Light reinforcement 10.61.11.5-1.1-1.1-0.8-0.91.1-1.0-1.2
Light reinforcement 20.20.30.60.30.40.40.5-0.80.70.3
Bone: marrow area0.00.10.1-0.3-0.3-0.3-0.3-0.0-0.3-0.4
Bone: maximum diameter0.30.50.70.80.70.80.8-0.20.80.7
Bone: maximum force0.71.21.8-1.0-1.1-1.1-1.11.3-1.0-1.1
Bone: maximum moment0.81.42.1-1.1-1.2-1.2-1.11.5-1.1-1.1
Mean time between licks in bursts1.31.92.21.41.31.31.3-1.31.41.5
Mean num. licks in bursts0.91.01.4-1.0-1.1-1.2-1.10.5-1.1-0.9
Cd content in liver2.73.03.9-1.3-1.5-1.8-1.82.0-1.9-1.8
Co content in liver0.00.00.10.10.00.10.10.20.10.4
Cu content in liver4.15.06.5-2.1-2.2-2.2-2.21.9-2.3-2.6
Fe content in liver2.12.53.1-1.1-1.5-1.7-1.71.7-1.6-1.8
K content in liver0.90.91.3-1.2-1.1-0.8-0.80.8-0.8-1.1
Mg content in liver0.00.00.1-0.2-0.20.20.2-0.10.2-0.1
Mn content in liver0.40.51.0-1.0-0.9-0.6-0.60.3-0.6-0.5
Na content in liver0.40.50.7-0.6-0.7-0.7-0.70.4-0.7-0.8
Rb content in liver1.11.31.9-0.6-0.9-1.3-1.31.4-1.2-1.3
Se content in liver0.10.10.2-0.2-0.5-0.2-0.20.30.1-0.5
Sr content in liver0.00.00.1-0.3-0.10.10.1-0.10.10.1
Zn content in liver4.65.15.8-2.2-2.4-2.2-2.22.1-2.2-2.4
Bone: minimum diameter0.40.81.00.90.90.90.9-0.71.01.0
Time in familiar zone, hab. session 11.51.42.21.51.31.21.1-0.91.21.0
Time in novel zone, hab. session 10.90.81.2-1.1-1.0-1.0-0.90.8-0.9-0.7
Total zone transitions, hab. session 10.40.61.5-1.2-1.0-0.7-0.70.4-0.8-0.5
Total locomotion distance, hab. session 10.20.30.7-0.8-0.7-0.5-0.50.3-0.6-0.5
Locomotion velocity, hab. session 10.30.40.8-0.9-0.7-0.5-0.50.3-0.6-0.6
Time in familiar zone, hab. session 20.70.71.11.00.80.80.8-0.50.90.8
Time in novel zone, hab. session 20.00.00.1-0.2-0.2-0.2-0.3-0.1-0.3-0.2
Total zone transitions, hab. session 20.00.10.3-0.6-0.3-0.0-0.00.1-0.1-0.0
Total locomotion distance, hab. session 20.30.40.7-0.8-0.7-0.5-0.50.4-0.5-0.7
Locomotion velocity, hab. session 20.20.30.7-0.8-0.6-0.4-0.40.3-0.5-0.6
Novel to familiar place preference ratio0.60.60.9-0.6-0.9-0.9-0.9-0.1-0.7-1.0
Novelty place preference0.60.61.0-0.6-0.9-1.0-0.9-0.1-0.7-1.0
Time in novel zone, NPP test0.80.81.2-0.7-1.0-1.1-1.00.1-0.8-1.1
Total zone transitions, NPP test1.92.85.3-2.3-1.9-1.5-1.51.2-1.6-1.5
Total locomotion distance, NPP test1.01.42.1-1.4-1.3-1.1-1.11.0-1.1-1.2
Locomotion velocity, NPP test1.01.52.2-1.5-1.4-1.1-1.10.9-1.1-1.2
Intraocular pressure0.91.32.0-0.8-1.1-1.2-1.40.8-1.1-1.4
Delta distance traveled before/after self-admin0.10.10.30.10.40.50.4-0.40.10.2
Delta ambulatory time before/after self-admin0.20.30.5-0.7-0.4-0.3-0.40.4-0.7-0.6
Parametrial fat weight1.12.12.7-1.7-1.5-1.4-1.61.3-1.5-1.2
Pavlov. Cond. lever latency5.26.67.8-2.3-2.6-2.8-2.72.3-2.6-2.6
Pavlov. Cond. magazine entry latency6.38.29.12.82.93.02.9-2.52.93.0
Pavlov. Cond. change in total contacts1.71.82.21.51.41.41.3-1.11.31.4
Pavlov. Cond. index score6.38.09.12.82.93.02.9-2.42.82.9
Pavlov. Cond. latency score6.27.99.12.72.93.02.9-2.52.82.9
Pavlov. Cond. lever contacts2.83.34.01.61.82.01.9-1.61.81.9
Pavlov. Cond. magazine entry number7.49.29.8-3.1-3.1-3.1-3.12.7-3.1-3.1
Pavlov. Cond. intertrial magazine entries0.20.30.5-0.5-0.6-0.6-0.60.4-0.4-0.7
Pavlov. Cond. lever-magazine prob. diff.5.66.98.02.62.72.82.7-2.12.62.7
Pavlov. Cond. response bias6.98.39.32.92.93.03.0-2.42.93.0
Pavlov. Cond. lever latency0.30.40.70.80.70.60.5-0.70.60.3
Pavlov. Cond. magazine entry latency0.20.20.40.20.40.50.6-0.30.60.6
Pavlov. Cond. change in total contacts2.02.83.4-1.8-1.7-1.6-1.61.8-1.7-1.4
Pavlov. Cond. index score0.00.10.2-0.4-0.2-0.1-0.00.4-0.10.1
Pavlov. Cond. latency score0.00.00.1-0.4-0.2-0.00.10.30.00.2
Pavlov. Cond. lever contacts0.71.01.6-1.3-1.1-1.0-0.91.0-1.0-0.7
Pavlov. Cond. magazine entry number0.40.50.7-0.6-0.7-0.8-0.80.5-0.8-0.9
Pavlov. Cond. intertrial magazine entries0.40.50.80.90.80.60.5-0.70.60.6
Pavlov. Cond. lever-magazine prob. diff.0.00.10.2-0.4-0.2-0.00.00.4-0.00.1
Pavlov. Cond. response bias0.00.00.1-0.4-0.2-0.00.00.2-0.10.2
Time in closed arm before self-admin1.51.72.0-1.4-1.4-1.3-1.41.4-1.3-0.9
Time in closed arm after self-admin0.00.00.00.2-0.2-0.2-0.20.10.10.1
Time in open arm before self-admin1.01.11.41.11.11.01.2-0.91.10.9
Time in open arm after self-admin0.30.41.00.50.50.50.5-1.00.60.3
Bone: periosteal estimation0.00.00.0-0.0-0.0-0.00.00.20.0-0.0
Bone: periosteal perimeter1.11.82.01.41.31.41.4-1.11.41.4
Bone: post-yield work0.00.00.0-0.2-0.1-0.1-0.10.1-0.1-0.2
Progressive ratio test 1 active lever presses0.10.10.2-0.00.10.20.2-0.4-0.00.3
Progressive ratio test 1 breakpoint0.10.10.30.10.20.30.3-0.50.10.3
Progressive ratio test 1 inactive lever presses0.40.40.60.60.70.80.7-0.30.60.7
Progressive ratio test 2 active lever presses0.80.91.20.71.11.11.1-0.90.71.0
Progressive ratio test 2 breakpoint0.50.60.80.60.90.90.9-0.70.60.8
Progressive ratio test 2 inactive lever presses1.51.82.51.21.61.61.6-0.71.21.3
Incentive Sensitization - Responses1.41.41.81.11.31.31.3-0.91.11.2
Incentive Sensitization - Breakpoint1.31.41.81.01.31.31.3-0.91.01.2
Sum of active levers in priming session hrs 5-60.70.70.9-0.9-0.7-0.8-0.80.7-0.9-0.9
Progressive ratio3.54.04.6-1.9-2.1-2.1-2.01.9-1.9-2.1
Food seeking constrained by brief footshock0.81.01.61.20.80.70.7-0.91.21.3
Seeking ratio, punishment vs. effort5.46.67.72.62.62.62.4-2.32.72.8
Retroperitoneal fat weight0.51.52.2-1.3-1.4-1.3-1.51.0-1.0-0.9
Reaction time number correct0.60.81.31.10.80.70.7-0.81.11.1
Reaction time mean minus median0.10.10.2-0.4-0.3-0.2-0.00.2-0.3-0.4
Reaction time mean minus median AUC0.20.30.4-0.6-0.5-0.4-0.30.3-0.6-0.7
Reaction time num false alarms0.30.40.50.60.60.70.6-0.70.60.5
Reaction time num false alarms AUC0.10.10.20.20.20.30.2-0.40.30.2
Reaction time trials correct on left0.60.81.31.10.80.70.7-0.81.11.1
Reaction time trials on left0.60.91.31.20.80.70.7-0.81.11.1
Reaction time mean0.00.00.00.0-0.1-0.2-0.0-0.20.00.1
Reaction time mean AUC0.00.00.10.10.0-0.10.0-0.30.10.2
Median of all reaction times0.00.00.10.1-0.0-0.2-0.1-0.20.10.3
Reaction time omissions0.10.20.30.60.50.40.4-0.50.30.4
Reaction time false alarm rate0.00.00.0-0.10.10.20.1-0.1-0.1-0.2
Reaction time premature initiation rate2.23.04.2-1.9-1.7-1.5-1.61.7-2.1-1.5
Reaction time premature initiations0.91.31.7-1.2-1.2-1.0-1.11.2-1.3-0.8
Std. dev. reaction times0.10.10.2-0.4-0.4-0.3-0.20.0-0.4-0.3
Reaction time trials completed0.60.91.31.20.80.70.7-0.81.11.1
Reaction time trials AUC0.81.11.71.30.90.80.8-0.91.21.3
Run reversals in cocaine runway, females2.32.23.61.91.21.21.2-1.31.71.7
Run reversals in cocaine runway, males1.01.01.7-1.1-0.9-0.9-0.81.3-1.1-0.9
Latency to leave start box in cocaine runway0.60.60.8-0.8-0.8-0.7-0.80.8-0.8-0.9
Latency to leave start box in cocaine runway, F1.61.82.8-1.2-1.3-1.3-1.41.7-1.2-1.2
Latency to leave start box in cocaine runway, M0.20.20.50.20.40.50.4-0.70.20.0
Std. dev. time between licks in bursts4.85.76.32.52.52.42.5-1.82.52.4
Total sessions with >9 infusions0.10.10.20.40.40.40.4-0.00.40.4
Short access day 1 total inactive lever presses5.56.27.32.72.42.32.3-2.32.72.7
Short access day 10 total inactive lever presses0.10.10.6-0.20.00.20.10.8-0.2-0.1
Short access day 1 total infusions1.11.21.41.11.21.11.1-1.01.11.1
Short access day 10 total infusions0.10.10.20.30.30.30.3-0.50.30.4
Short access total infusions0.80.91.31.00.90.80.9-1.11.01.1
Short access day 1 locomotion0.00.00.10.20.20.20.2-0.20.20.1
Short access day 10 total locomotion0.00.00.1-0.1-0.1-0.2-0.2-0.3-0.10.2
Short access total locomotion0.00.00.2-0.10.00.10.0-0.4-0.10.0
One hour access (0.3 mA shock)0.30.40.70.50.60.60.6-0.80.50.6
Compulsive drug intake0.20.20.70.50.20.20.2-0.80.50.3
One hour access (shock baseline)0.10.10.1-0.10.40.40.4-0.0-0.10.1
Social response proportion0.50.61.1-0.5-0.8-1.1-0.70.8-0.8-0.5
Social responses0.40.50.7-0.8-0.7-0.8-0.40.7-0.8-0.8
Social time0.30.40.80.50.80.70.9-0.00.70.7
Soleus weight3.610.611.6-3.4-3.3-3.2-3.23.4-3.1-3.2
Bone: stiffness0.20.20.3-0.4-0.5-0.5-0.50.5-0.5-0.5
Tibialis anterior weight0.00.00.2-0.3-0.1-0.0-0.10.4-0.10.0
Time to tail flick, vehicle, before self-admin2.02.12.6-1.4-1.4-1.6-1.41.4-1.4-1.4
Time to tail flick, vehicle, after self-admin1.11.22.2-1.2-0.9-0.9-1.01.5-1.2-0.9
Time to tail flick, test, before self-admin0.10.10.2-0.4-0.5-0.3-0.5-0.1-0.3-0.2
Time to tail flick, test, after self-admin0.00.00.1-0.00.30.20.30.2-0.00.2
Delta time to tail flick, vehicle, before/after SA0.30.30.50.30.70.70.6-0.10.40.6
Delta time to tail flick, test, before/after SA0.30.30.50.40.70.60.7-0.20.40.6
Tibia length6.518.422.8-4.8-4.4-4.1-4.24.3-4.1-4.1
Ambulatory time before self-admin0.20.20.50.60.50.40.4-0.10.50.7
Ambulatory time after self-admin0.10.10.30.30.40.30.3-0.30.20.6
Bone: tissue strength2.82.74.0-1.6-1.6-1.6-1.62.0-1.6-1.6
Total heroin consumption0.91.11.9-1.1-0.9-0.9-0.91.4-1.1-0.9
Bone: trabecular number0.81.32.61.11.01.01.0-1.61.11.1
Bone: trabecular spacing1.62.03.7-1.3-1.4-1.3-1.31.9-1.4-1.4
Bone: trabecular thickness0.00.00.1-0.2-0.2-0.2-0.1-0.30.0-0.1
Bone: trabecular tissue density0.30.40.6-0.7-0.6-0.5-0.60.5-0.6-0.7
Water consumed over 24 hours0.00.00.3-0.1-0.1-0.1-0.00.5-0.1-0.0
Number of responses in last shaping day0.70.71.20.71.01.11.1-0.50.70.8