Hub : Genes

Rpap3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Rpap3 0.21 0.1 0.0e+00 0.29 0.29 0.28 0.28 1.7e-32 1.3e-31 1.5e-31 1.8e-31
2 PL alternative TSS XM_017594782.2 0.09 0.1 6.1e-06 0.04 0.04 0.04 0.04 1.5e-05 1.1e-05 4.3e-05 2.0e-05
3 PL alternative TSS NM_001004243.1 0.03 0.03 7.3e-04 0.02 0.03 0.03 0.02 1.4e-03 5.5e-04 6.5e-04 9.6e-04
4 pVTA gene expression Rpap3 0.28 0.13 1.2e-12 0.25 0.28 0.23 0.27 3.2e-11 2.3e-12 2.4e-10 3.8e-12
5 Liver mRNA stability Rpap3 0.11 0.09 5.1e-11 0.07 0.09 0.08 0.08 1.0e-08 9.7e-10 4.0e-09 2.6e-09
6 NAcc gene expression Rpap3 0.23 0.12 0.0e+00 0.26 0.26 0.25 0.26 2.4e-29 2.2e-29 4.7e-29 1.7e-29
7 Brain gene expression Rpap3 0.19 0.11 0.0e+00 0.22 0.23 0.22 0.23 1.6e-20 5.3e-21 2.7e-20 9.5e-21
8 BLA gene expression Rpap3 0.53 0.21 0.0e+00 0.43 0.41 0.4 0.41 6.2e-25 1.6e-23 4.6e-23 3.2e-23
9 Liver alternative TSS XM_017594786.2 0.03 0.03 2.0e-03 0.02 0.02 0.01 0.01 6.0e-03 5.6e-03 3.8e-02 9.9e-03
10 Adipose mRNA stability Rpap3 0.09 0.07 8.6e-10 0.06 0.07 0.05 0.06 7.4e-07 1.5e-08 5.3e-06 1.5e-07
11 Liver gene expression Rpap3 0.5 0.15 0.0e+00 0.45 0.46 0.45 0.45 3.7e-55 4.5e-56 3.1e-55 2.3e-55
12 Brain mRNA stability Rpap3 0.1 0.07 3.8e-11 0.11 0.12 0.12 0.11 3.0e-10 4.6e-11 2.6e-11 9.2e-11
13 NAcc intron excision ratio chr7_128838537_128839475 0.03 0.03 7.1e-04 0.02 0.02 0.01 0.01 5.4e-03 1.0e-03 3.3e-02 5.7e-03
14 Adipose gene expression Rpap3 0.09 0.07 1.6e-08 0.05 0.06 0.06 0.06 1.3e-06 1.6e-07 3.6e-07 7.6e-07
15 PL alternative TSS XM_017594782.2 0.08 0.08 7.0e-06 0.04 0.04 0.04 0.04 1.2e-05 1.5e-05 7.0e-05 2.6e-05
16 OFC mRNA stability Rpap3 0.26 0.39 8.2e-03 0.09 0.06 0.04 0.07 4.8e-03 1.7e-02 3.7e-02 9.0e-03
17 OFC gene expression Rpap3 0.35 0.19 4.9e-07 0.21 0.23 0.22 0.23 8.0e-06 4.3e-06 4.8e-06 4.2e-06
18 PL isoform ratio XM_008765690.3 0.02 0.02 6.4e-03 0.01 0.01 0 0.01 1.7e-02 3.3e-02 9.2e-02 2.3e-02
19 IL intron excision ratio chr7_128814428_128815307 0.13 0.13 8.7e-03 0.08 0.08 0.08 0.09 5.3e-03 6.1e-03 6.1e-03 4.3e-03
20 IL intron excision ratio chr7_128813961_128814331 0.18 0.16 9.7e-04 0.13 0.12 0.12 0.13 6.3e-04 9.0e-04 7.5e-04 5.3e-04
21 Liver isoform ratio XM_017594784.2 0.04 0.04 3.1e-04 0.03 0.03 0.03 0.03 1.9e-04 4.2e-04 7.5e-04 3.9e-04
22 LHb gene expression Rpap3 0.25 0.26 1.5e-03 0.1 0.09 0.14 0.1 2.1e-03 3.4e-03 3.8e-04 2.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density7.112.013.73.6-3.63.7-3.6-3.6-3.7-3.53.53.6-3.5-3.43.4-3.5-3.53.53.3-3.33.23.3-3.33.42.7
Area under the delay curve1.71.73.21.3-1.41.3-1.3-1.3-1.4-1.41.41.3-1.3-1.41.5-1.3-1.31.81.0-1.21.31.0-1.00.81.8
BMI with tail4.414.119.94.5-4.24.1-4.1-4.1-4.1-4.14.34.0-4.0-4.03.5-4.0-3.93.53.5-3.52.92.9-2.82.82.9
BMI without tail0.10.20.50.7-0.50.5-0.4-0.5-0.5-0.40.40.4-0.3-0.30.2-0.3-0.30.30.0-0.0-0.3-0.50.6-0.60.2
Body weight6.627.935.05.9-5.95.8-5.8-5.7-5.7-5.85.95.6-5.6-5.65.3-5.6-5.55.34.8-5.04.43.8-3.83.84.6
Weight adjusted by age1.92.23.51.8-1.91.8-1.7-1.8-1.8-1.81.61.7-1.6-1.61.7-1.6-1.51.50.8-1.21.00.7-0.60.60.6
Bone surface9.817.218.64.2-4.24.3-4.3-4.3-4.3-4.24.24.3-4.3-4.24.2-4.2-4.24.24.1-4.24.04.0-4.04.13.1
Bone volume6.210.612.03.4-3.43.5-3.4-3.4-3.5-3.33.33.4-3.4-3.23.3-3.3-3.33.33.2-3.23.03.1-3.13.22.4
Breakpoint value in progressive ratio session0.40.52.10.2-0.20.3-0.3-0.4-0.3-0.30.40.4-0.5-0.40.4-0.5-0.50.41.0-0.71.21.4-1.41.5-0.0
Number of licking bursts0.40.42.0-0.50.4-0.40.50.40.50.5-0.5-0.50.50.6-0.40.50.6-0.6-0.70.6-0.8-0.80.8-0.8-1.4
Context. condit. distance diff. score0.40.50.70.8-0.70.7-0.7-0.7-0.8-0.70.70.7-0.7-0.70.8-0.7-0.70.70.9-0.70.80.7-0.70.70.2
Locomotion velocity, session 10.70.72.0-0.70.6-0.70.70.70.60.6-0.7-0.80.80.7-0.70.70.8-0.6-1.20.8-1.2-1.41.4-1.4-0.3
Locomotion distance, session 12.93.74.8-1.81.8-1.91.91.91.91.9-1.9-1.91.91.8-2.11.91.9-1.8-2.12.0-1.8-2.22.2-2.2-1.1
Locomotion velocity, session 20.20.20.3-0.40.5-0.50.50.50.40.4-0.5-0.50.50.4-0.60.40.4-0.4-0.50.2-0.5-0.50.5-0.40.4
Locomotion distance, session 22.13.03.6-1.81.8-1.81.81.81.91.7-1.8-1.81.81.6-1.91.71.7-1.7-1.71.6-1.6-1.81.8-1.8-0.4
Locomotion velocity, session 33.13.64.5-1.91.9-1.91.91.92.01.8-1.9-1.91.91.8-2.11.91.9-2.0-1.91.8-2.0-2.12.1-1.9-0.7
Locomotion distance, session 35.05.56.0-2.42.4-2.42.42.42.42.4-2.4-2.42.42.3-2.42.42.4-2.4-2.12.1-2.3-2.42.4-2.4-1.7
Stereotopy head waving bouts, day 30.80.91.21.0-1.01.0-1.0-1.0-1.0-1.01.01.0-1.0-0.91.0-1.0-1.01.01.0-1.01.11.0-1.01.00.2
Stereotopy head waving duration, day 30.20.30.40.6-0.50.5-0.5-0.5-0.6-0.50.50.5-0.5-0.50.6-0.5-0.50.60.5-0.60.60.5-0.50.50.3
Locomotion velocity, session 70.10.10.3-0.20.1-0.10.10.10.20.1-0.2-0.10.10.1-0.30.20.2-0.4-0.30.0-0.5-0.60.6-0.4-0.3
Locomotion distance, session 71.41.82.7-1.21.2-1.21.21.21.31.2-1.2-1.21.21.3-1.31.31.3-1.4-1.51.3-1.6-1.61.6-1.6-1.3
Stereotopy head waving bouts, day 71.11.22.11.1-1.11.1-1.0-1.1-1.0-1.11.11.1-1.1-1.11.2-1.1-1.11.11.4-1.21.11.1-1.11.10.8
Stereotopy head waving duration, day 72.12.53.81.5-1.41.4-1.4-1.5-1.4-1.51.51.5-1.5-1.61.6-1.5-1.61.51.9-1.81.81.8-1.81.81.4
Locomotion velocity, session 80.20.30.90.4-0.40.4-0.4-0.4-0.4-0.50.50.5-0.5-0.60.4-0.5-0.50.50.7-0.70.50.4-0.40.51.0
Locomotion distance, session 80.71.11.5-1.21.2-1.21.21.21.21.1-1.2-1.11.11.0-1.11.11.1-1.0-0.70.8-0.7-1.01.0-1.0-0.2
Degree of sensitization distance0.70.71.10.9-1.01.0-1.0-1.0-0.9-1.01.00.9-0.9-0.90.9-0.9-0.80.80.4-0.60.50.5-0.50.40.4
Degree of sensitization stereotypy0.80.81.70.8-0.80.8-0.8-0.8-0.7-0.90.80.8-0.9-0.91.0-0.9-0.90.81.3-1.11.11.0-1.11.10.5
Conditioned locomotion0.10.10.5-0.00.0-0.00.10.00.10.1-0.1-0.10.10.2-0.20.20.2-0.3-0.40.2-0.6-0.70.7-0.7-0.6
Cocaine response after cond. corrected0.20.22.70.1-0.30.2-0.3-0.2-0.2-0.30.30.2-0.2-0.4-0.0-0.3-0.30.30.2-0.10.30.1-0.10.11.6
Cocaine response after cond. not corrected0.70.81.2-1.10.8-0.90.80.90.90.9-0.8-0.90.90.8-1.10.90.8-0.9-0.91.0-0.8-1.01.0-1.00.4
Cocaine response before conditioning6.67.99.2-3.03.0-2.92.92.82.93.0-3.0-2.92.93.0-2.72.92.9-2.9-2.52.8-2.6-2.52.5-2.4-3.0
Saline control response0.10.10.4-0.40.4-0.30.40.30.30.4-0.4-0.30.40.5-0.20.40.4-0.2-0.20.3-0.2-0.20.2-0.2-0.6
Bone: connectivity density5.68.89.33.0-3.03.1-3.1-3.0-3.0-2.93.03.0-3.0-3.02.9-3.0-3.03.02.9-2.92.93.0-3.03.02.6
Bone: cortical apparent density0.50.61.1-0.80.8-0.80.80.80.70.8-0.8-0.80.80.8-0.70.80.8-0.7-0.70.8-0.6-0.70.7-0.8-1.0
Bone: cortical area9.414.216.54.1-3.93.9-3.9-3.9-3.9-3.93.83.9-3.9-3.83.9-3.9-3.83.83.9-3.73.73.5-3.53.52.5
Bone: cortical porosity2.42.76.4-1.71.6-1.51.61.51.71.6-1.6-1.61.61.7-1.51.61.6-1.8-1.51.6-1.4-1.41.4-1.4-2.5
Bone: cortical porosity2.83.07.9-1.91.8-1.71.81.71.91.8-1.8-1.71.71.8-1.61.71.7-1.9-1.41.6-1.3-1.31.3-1.3-2.8
Bone: cortical thickness4.06.57.82.7-2.62.6-2.6-2.6-2.7-2.52.62.6-2.6-2.52.6-2.6-2.62.52.8-2.52.62.4-2.42.41.8
Bone: cortical thickness0.20.20.80.6-0.60.6-0.6-0.5-0.4-0.50.50.5-0.5-0.50.4-0.5-0.50.40.4-0.10.20.0-0.00.00.9
Bone: cortical tissue density0.60.81.2-1.00.9-0.90.90.90.90.9-0.9-0.90.90.9-0.80.90.9-0.8-0.80.9-0.7-0.80.8-0.9-1.1
Condit. Reinf. active minus inactive responses0.20.20.7-0.40.3-0.30.30.30.30.3-0.3-0.30.30.2-0.50.30.3-0.3-0.50.2-0.7-0.60.6-0.60.8
Condit. Reinf. active-inactive response ratio0.10.21.50.3-0.30.3-0.4-0.3-0.3-0.40.40.3-0.3-0.40.2-0.3-0.30.40.3-0.30.10.2-0.20.21.2
Condit. Reinf. active responses0.70.91.7-0.90.8-0.80.80.90.90.8-0.8-0.90.90.8-0.90.90.9-0.8-1.20.8-1.3-1.21.3-1.20.3
Condit. Reinf. inactive responses3.23.85.7-1.91.7-1.81.81.81.91.8-1.8-1.91.91.9-1.71.91.9-1.7-2.32.0-2.2-2.42.4-2.2-1.6
Incentive salience index mean0.00.10.90.0-0.10.1-0.1-0.1-0.1-0.10.10.1-0.1-0.20.1-0.1-0.10.2-0.0-0.3-0.20.0-0.0-0.00.9
Condit. Reinf. lever presses0.20.31.00.4-0.40.5-0.5-0.5-0.5-0.50.40.5-0.5-0.40.5-0.5-0.50.60.3-0.60.30.6-0.50.51.0
Condit. Reinf. active minus inactive responses0.00.10.3-0.1-0.0-0.10.10.00.10.0-0.0-0.10.10.10.10.10.1-0.0-0.20.2-0.4-0.50.5-0.5-0.0
Condit. Reinf. active-inactive response ratio0.40.41.5-0.50.3-0.40.40.40.50.3-0.3-0.50.50.4-0.50.50.5-0.4-1.00.7-1.0-1.21.2-1.20.2
Condit. Reinf. active responses0.20.30.7-0.60.5-0.50.50.50.50.5-0.5-0.50.50.5-0.20.50.6-0.4-0.50.5-0.7-0.80.8-0.8-0.3
Condit. Reinf. inactive responses0.91.11.3-1.11.1-1.11.11.11.11.1-1.1-1.11.11.1-0.81.11.1-1.0-0.90.9-1.0-1.01.0-1.0-1.1
Condit. Reinf. lever presses0.00.00.1-0.20.2-0.10.20.10.10.1-0.1-0.10.10.10.10.10.1-0.00.2-0.20.2-0.00.00.00.0
Condit. Reinf. lever reinforcers received0.50.71.1-0.90.8-0.80.80.80.90.8-0.8-0.80.80.8-0.60.80.9-0.7-0.80.7-0.9-1.01.0-1.0-0.5
Conditioned reinforcement - actives1.31.31.9-1.31.3-1.21.21.21.41.2-1.2-1.21.21.2-1.21.21.2-1.1-1.21.0-1.0-0.70.7-0.6-1.0
Conditioned reinforcement - inactives0.80.91.4-1.21.1-1.11.11.11.21.1-1.0-1.11.11.0-0.91.01.0-0.8-0.91.0-0.9-0.70.7-0.6-0.1
Conditioned locomotion0.20.20.7-0.60.6-0.60.60.50.60.6-0.6-0.50.50.6-0.10.50.5-0.4-0.10.3-0.2-0.20.2-0.1-0.8
Patch foraging indifference point 0 sec1.42.22.7-1.21.5-1.51.51.51.41.5-1.6-1.51.51.5-1.41.51.5-1.7-1.61.5-1.7-1.41.4-1.3-1.3
Patch foraging indifference point AUC0.10.10.3-0.50.3-0.30.30.30.50.3-0.2-0.30.30.2-0.10.30.3-0.1-0.20.2-0.1-0.20.2-0.2-0.2
Delay disc. indifference point, 0s delay1.41.52.41.4-1.51.4-1.4-1.4-1.4-1.41.41.3-1.3-1.31.6-1.3-1.31.51.3-1.11.00.5-0.50.40.8
Delay disc. indifference point, 16s delay1.81.83.01.3-1.41.4-1.4-1.4-1.4-1.41.41.4-1.3-1.41.6-1.3-1.31.71.0-1.31.41.1-1.11.01.3
Delay disc. indifference point, 2s delay0.91.01.81.1-1.21.1-1.1-1.1-1.1-1.11.01.0-1.0-1.01.1-1.0-0.91.40.3-0.90.60.5-0.50.41.2
Delay disc. indifference point, 24s delay1.41.42.21.3-1.31.3-1.3-1.3-1.3-1.31.31.2-1.2-1.21.3-1.2-1.21.51.0-1.11.10.8-0.80.80.8
Delay disc. indifference point, 4s delay0.50.52.00.7-0.80.7-0.7-0.7-0.8-0.70.70.7-0.7-0.80.7-0.7-0.71.00.5-0.60.30.6-0.50.41.4
Delay disc. indifference point, 8s delay4.24.38.12.0-2.02.0-2.0-2.0-2.1-2.12.02.0-2.0-2.12.3-2.0-2.02.62.0-2.22.11.6-1.61.32.8
Indifference point function ln k2.83.95.72.4-2.32.3-2.2-2.2-2.3-2.32.22.2-2.1-2.12.1-2.1-2.12.01.9-1.81.41.2-1.11.21.0
Indifference point function log k2.83.95.72.4-2.32.3-2.2-2.2-2.3-2.32.22.2-2.1-2.12.1-2.1-2.12.01.9-1.81.41.2-1.11.21.0
Patch foraging total patch changes 0 sec1.32.12.6-1.21.5-1.51.51.51.41.5-1.6-1.51.51.5-1.31.51.5-1.6-1.41.4-1.6-1.31.3-1.2-1.3
Patch foraging total patch changes 12 sec1.01.31.8-1.31.3-1.31.31.31.31.3-1.3-1.21.21.2-1.11.21.2-1.2-0.90.9-0.9-0.50.5-0.6-1.0
Patch foraging total patch changes 18 sec2.93.75.2-2.12.0-2.02.02.02.12.0-1.9-2.02.02.1-1.62.02.0-1.9-2.01.8-1.9-1.31.3-1.4-2.3
Patch foraging total patch changes 24 sec1.01.21.7-1.11.2-1.21.21.11.11.2-1.2-1.21.11.2-0.91.21.2-1.1-1.11.0-1.1-0.90.9-0.9-1.3
Patch foraging total patch changes 6 sec2.23.23.8-1.91.9-1.91.91.91.91.9-1.8-1.91.81.9-1.61.81.9-1.7-1.91.8-2.0-1.51.5-1.4-1.5
Patch foraging time to switch 0 sec2.94.55.5-2.32.3-2.32.32.22.22.3-2.3-2.22.22.3-2.22.22.2-2.2-1.92.1-2.0-1.61.6-1.7-2.0
Patch foraging water rate 0 sec4.57.18.02.8-2.72.7-2.7-2.7-2.7-2.82.62.8-2.7-2.82.8-2.7-2.82.62.7-2.82.72.4-2.42.52.2
Patch foraging water rate 12 sec3.45.26.62.3-2.42.4-2.3-2.4-2.3-2.42.32.4-2.4-2.42.6-2.3-2.32.52.4-2.52.11.7-1.71.62.0
Patch foraging water rate 18 sec0.81.01.91.0-1.01.0-1.0-1.0-1.0-1.10.91.1-1.0-1.11.2-1.0-1.01.11.3-1.11.00.5-0.50.61.4
Patch foraging water rate 24 sec3.75.17.82.3-2.02.1-2.0-2.2-2.2-2.12.12.2-2.2-2.22.2-2.2-2.22.12.8-2.72.42.6-2.62.71.0
Patch foraging water rate 6 sec4.76.99.02.7-2.62.6-2.6-2.6-2.7-2.72.52.7-2.6-2.72.9-2.6-2.72.92.8-3.02.22.4-2.42.42.5
Seeking ratio, delayed vs. immediate footshock0.30.31.80.6-0.60.5-0.6-0.5-0.6-0.60.60.5-0.5-0.60.5-0.5-0.50.60.3-0.5-0.10.4-0.40.21.3
Distance traveled before self-admin1.01.01.7-1.01.0-1.01.01.01.01.1-1.1-1.11.01.1-0.91.01.1-1.0-1.31.1-0.6-0.70.6-0.6-1.2
Distance traveled after self-admin0.20.20.8-0.30.5-0.40.40.30.20.4-0.3-0.20.20.20.20.20.10.00.8-0.30.90.9-0.90.90.2
Extensor digitorum longus weight6.224.228.34.8-5.25.1-5.1-5.1-4.9-5.25.25.1-5.1-5.25.3-5.1-5.15.24.8-4.84.74.5-4.54.53.6
Bone: elastic displacement4.65.26.2-2.42.5-2.42.52.42.42.4-2.5-2.42.42.4-2.32.42.4-2.4-2.12.1-1.9-2.02.0-1.9-2.1
Bone: elastic work0.10.10.8-0.30.4-0.30.30.30.40.4-0.4-0.30.30.4-0.10.30.3-0.3-0.10.20.10.1-0.10.2-0.9
Bone: endosteal estimation7.115.417.24.0-4.14.1-4.1-4.1-4.0-4.14.14.1-4.1-4.14.1-4.1-4.04.03.7-4.03.73.7-3.73.82.6
Bone: endosteal perimeter6.413.314.83.8-3.83.8-3.8-3.8-3.7-3.83.83.8-3.8-3.73.8-3.8-3.83.83.5-3.63.43.4-3.43.52.2
Epididymis fat weight0.71.62.61.2-1.21.2-1.2-1.2-1.2-1.31.31.3-1.2-1.41.4-1.2-1.31.41.6-1.41.41.0-1.00.91.2
Delta time in closed arm before/after self-admin0.10.10.40.3-0.30.3-0.3-0.3-0.2-0.30.40.3-0.3-0.4-0.1-0.3-0.3-0.00.4-0.30.20.1-0.10.10.6
Delta time in open arm before/after self-admin3.23.13.9-2.01.9-1.91.91.91.81.9-1.9-1.91.91.9-1.31.91.9-1.4-1.81.8-1.4-1.41.4-1.3-1.6
Diff in mean of infusions in LGA sessions0.91.01.51.0-1.21.1-1.2-1.1-1.1-1.11.21.1-1.1-1.10.9-1.1-1.10.91.1-0.70.51.0-1.01.00.1
Delay discount exponential model param1.41.53.0-1.21.3-1.21.21.21.31.2-1.2-1.21.21.2-1.41.21.2-1.7-0.81.1-1.2-0.90.9-0.7-1.7
Extinction: sum of active levers before priming0.80.82.10.6-0.80.8-0.8-0.7-0.6-0.70.90.7-0.8-0.70.8-0.8-0.80.80.6-0.71.41.5-1.51.4-0.2
Active lever presses in extinction session 60.30.30.70.6-0.70.7-0.7-0.6-0.6-0.70.70.6-0.6-0.70.5-0.6-0.60.90.4-0.4-0.1-0.0-0.00.10.7
Bone: final force9.815.817.44.2-4.04.1-4.1-4.1-4.1-4.04.14.1-4.1-4.04.1-4.1-4.14.14.0-3.93.83.9-3.93.93.2
Bone: final moment9.916.117.74.2-4.14.1-4.1-4.1-4.1-4.04.14.1-4.1-4.04.1-4.1-4.14.14.0-3.93.83.9-3.93.93.3
Food consumed during 24 hour testing period1.31.52.41.2-1.21.2-1.2-1.2-1.2-1.21.21.2-1.2-1.31.2-1.2-1.31.31.3-1.21.31.2-1.21.11.6
Glucose0.10.10.20.4-0.40.4-0.4-0.4-0.4-0.30.30.3-0.3-0.30.2-0.3-0.30.30.1-0.20.00.1-0.10.1-0.2
Heart weight0.10.23.0-0.1-0.20.1-0.1-0.00.0-0.20.20.0-0.0-0.2-0.1-0.1-0.10.3-0.4-0.1-0.5-0.20.2-0.31.7
Delay discount hyperbolic model param1.31.42.8-1.21.2-1.21.21.21.31.2-1.2-1.11.11.2-1.31.11.1-1.6-0.71.0-1.1-0.90.9-0.7-1.7
Intermittent access intake day 1-15 change1.01.02.6-0.91.0-1.01.11.00.90.9-0.9-0.91.00.8-0.71.01.0-0.5-0.90.7-1.0-1.61.6-1.50.6
Intermittent access intake escalation0.70.71.9-0.70.8-0.80.80.80.60.7-0.6-0.70.80.6-0.50.80.8-0.2-0.70.5-0.9-1.41.3-1.41.0
Intermittent access intake escalation 20.70.61.0-1.01.0-1.01.01.00.80.9-0.8-0.90.90.8-0.60.90.8-0.5-0.80.7-0.6-0.70.7-0.60.6
Intermitt. access day 1 inactive lever presses3.13.34.9-2.01.9-1.91.91.92.11.9-2.0-1.91.92.0-1.61.91.9-1.8-1.81.8-1.7-1.41.4-1.1-2.2
Intermitt. access day 15 inactive lever presses1.21.43.1-1.00.8-0.90.90.91.00.9-0.9-1.01.01.0-1.11.01.1-1.3-1.11.4-1.4-1.71.7-1.6-1.2
Intermitt. access escalation Index0.50.41.3-0.40.8-0.60.50.60.50.7-0.7-0.60.50.7-0.80.50.5-0.9-0.70.1-0.00.9-0.91.1-0.2
Intermittent access day 1 total infusions1.41.62.1-1.11.2-1.31.21.31.21.3-1.2-1.31.31.3-1.41.31.3-1.3-1.41.5-1.3-1.11.1-1.2-0.6
Intermittent access day 15 total infusions2.32.63.5-1.51.5-1.61.61.61.51.6-1.5-1.61.71.6-1.51.61.7-1.3-1.91.7-1.8-1.91.9-1.9-0.2
Intermittent access terminal intake (last 3 days)2.32.63.1-1.51.6-1.61.61.61.51.6-1.6-1.71.71.6-1.51.71.7-1.4-1.81.7-1.7-1.81.8-1.7-0.4
Intermittent access total infusions2.22.42.8-1.51.6-1.61.71.61.51.6-1.6-1.61.61.6-1.41.61.6-1.3-1.61.6-1.6-1.51.5-1.4-0.6
Intermittent access day 1 locomotion1.21.32.4-1.01.0-1.01.11.01.11.0-1.0-1.01.11.1-1.01.11.1-1.0-1.11.2-1.2-1.51.5-1.5-1.2
Intermittent access day 15 total locomotion1.01.12.1-1.00.9-0.91.00.91.01.0-0.8-1.01.01.1-0.81.01.1-0.8-1.21.2-1.2-1.11.1-1.2-1.5
Intermittent access total locomotion2.22.53.7-1.71.7-1.71.71.61.71.7-1.6-1.61.61.7-1.11.71.7-1.2-1.31.5-1.3-1.51.5-1.5-1.9
Intermittent access standard deviation0.80.82.4-0.60.7-0.80.80.80.70.8-0.7-0.80.80.8-0.70.80.8-0.5-0.91.1-1.0-1.51.5-1.3-0.3
Left kidney weight0.61.65.71.1-1.21.1-1.2-1.1-1.2-1.21.31.1-1.1-1.31.1-1.2-1.21.40.9-1.00.91.2-1.21.22.4
Right kidney weight2.77.710.13.1-3.23.1-3.1-3.0-3.1-3.03.02.9-2.9-2.92.8-2.9-2.93.02.0-2.32.12.2-2.22.42.4
Cocaine induced anxiety1.11.32.51.0-1.11.1-1.1-1.2-1.0-1.21.21.2-1.2-1.21.2-1.2-1.20.91.6-1.31.21.1-1.11.20.4
Post-drug Anxiety4.65.27.52.1-2.02.1-2.1-2.2-2.1-2.12.12.2-2.2-2.22.2-2.2-2.22.22.5-2.62.52.7-2.72.71.6
Baseline Anxiety1.31.32.81.2-1.01.1-1.1-1.0-1.2-1.01.01.1-1.1-0.90.8-1.1-1.11.10.6-1.01.21.7-1.71.61.3
Tail length0.10.31.2-0.30.2-0.30.30.30.30.2-0.4-0.30.40.4-0.20.40.4-0.0-0.80.5-0.6-1.11.1-1.00.2
Length with tail2.07.39.32.8-3.02.9-2.9-2.9-2.9-3.03.02.9-2.8-2.92.9-2.8-2.83.12.2-2.52.31.8-1.81.82.9
Length without tail7.817.119.14.2-4.44.3-4.3-4.2-4.2-4.34.44.2-4.3-4.44.0-4.3-4.34.13.9-4.03.73.8-3.83.74.0
Times rat made contact with spout0.10.10.90.3-0.30.3-0.3-0.3-0.2-0.30.30.3-0.3-0.40.4-0.3-0.40.30.5-0.40.30.2-0.30.40.9
Lifetime Intake1.61.82.1-1.41.4-1.41.41.41.31.4-1.4-1.41.41.4-1.21.41.4-1.1-1.41.4-1.4-1.41.3-1.2-0.4
Liver weight, left2.33.76.41.8-1.61.7-1.7-1.7-1.8-1.61.71.8-1.8-1.71.9-1.8-1.81.92.1-2.02.42.5-2.52.41.3
Liver weight, right2.03.34.42.0-1.91.8-1.9-1.8-1.9-1.81.81.8-1.8-1.71.8-1.8-1.81.91.4-1.61.91.9-1.81.72.1
Locomotor activity0.91.43.1-1.01.2-1.21.21.21.21.2-1.2-1.21.21.3-1.31.21.2-1.4-1.11.1-1.3-0.80.8-0.8-1.8
Locomotor testing distance2.74.47.2-1.92.1-2.12.12.12.12.2-2.1-2.22.12.2-2.32.12.1-2.3-2.02.2-2.1-1.71.6-1.7-2.7
Locomotor testing rearing2.64.06.4-1.81.9-1.91.92.01.92.1-2.0-2.02.02.2-2.12.02.1-2.0-2.42.2-2.1-1.61.6-1.5-2.5
Locomotion in novel chamber0.70.81.31.0-1.21.1-1.1-1.0-1.1-1.11.01.0-1.0-1.01.1-1.0-1.01.00.2-0.70.30.5-0.60.70.6
Locomotion in novel chamber post-restriction0.70.91.70.8-0.80.8-0.8-0.9-0.9-0.90.80.9-0.9-0.91.2-0.9-0.91.20.8-1.20.80.9-0.90.71.3
Fecal boli incidents, locomotor time 10.50.61.0-0.91.0-0.90.90.90.80.9-0.9-0.80.80.7-0.90.80.7-0.7-0.00.4-0.3-0.30.3-0.40.8
Change in fecal boli incidents, locomotor task0.60.61.10.9-1.11.0-1.0-0.9-0.9-0.90.90.8-0.8-0.70.9-0.8-0.70.9-0.1-0.3-0.10.4-0.40.30.1
Time >=10cm from walls, locomotor time 10.90.93.70.8-0.70.7-0.7-0.8-0.9-0.80.70.8-0.8-0.90.7-0.8-0.90.80.9-1.21.20.9-0.91.11.9
Bouts of movement, locomotor time 10.20.30.80.5-0.50.5-0.5-0.4-0.3-0.40.60.5-0.5-0.5-0.0-0.5-0.5-0.20.7-0.40.90.8-0.70.40.4
Total resting periods, locomotor time 10.10.10.6-0.10.1-0.10.10.10.30.10.0-0.10.10.0-0.60.10.1-0.80.10.20.30.2-0.2-0.1-0.0
Rest time, locomotor task time 10.10.10.8-0.20.2-0.20.20.30.50.3-0.2-0.30.20.2-0.90.20.2-0.8-0.40.5-0.2-0.0-0.00.2-0.3
Distance moved, locomotor task time 10.10.10.2-0.40.5-0.40.50.30.20.3-0.4-0.30.30.30.20.30.30.2-0.0-0.20.1-0.10.1-0.20.2
Vertical activity count, locomotor time 11.31.43.01.1-1.01.1-1.1-1.1-1.2-1.11.01.1-1.1-1.11.1-1.1-1.11.21.2-1.41.11.3-1.31.01.7
Time >=10cm from walls, locomotor time 20.20.20.5-0.50.6-0.50.50.50.50.5-0.6-0.50.40.5-0.60.40.4-0.7-0.30.20.00.1-0.10.00.0
Bouts of movement, locomotor time 23.33.54.61.9-2.01.9-1.9-2.0-1.9-1.91.91.9-1.9-1.92.0-1.9-1.91.81.8-1.92.11.9-1.81.70.9
Total resting periods, locomotor time 23.33.54.32.0-2.02.0-2.0-2.0-2.0-2.02.02.0-2.0-1.92.1-2.0-1.91.91.7-1.92.11.7-1.61.50.9
Rest time, locomotor task time 20.10.10.30.5-0.60.5-0.5-0.4-0.4-0.50.60.4-0.4-0.40.1-0.4-0.40.10.0-0.00.0-0.00.00.20.1
Distance moved, locomotor task time 20.30.30.6-0.70.8-0.70.70.60.60.7-0.7-0.60.60.7-0.40.60.6-0.5-0.30.30.20.1-0.20.2-0.6
Vertical activity count, locomotor time 20.30.41.30.5-0.40.4-0.5-0.4-0.4-0.40.40.5-0.5-0.50.5-0.5-0.50.50.7-0.50.81.1-1.11.1-0.0
Light reinforcement 12.85.07.4-2.22.3-2.32.32.22.32.3-2.2-2.32.32.4-2.02.32.3-2.0-2.12.2-2.2-2.22.2-2.1-2.7
Light reinforcement 21.11.53.0-1.11.0-1.11.11.11.11.1-1.0-1.11.11.1-1.11.21.2-1.1-1.21.2-1.4-1.71.7-1.6-0.8
Bone: marrow area7.215.617.54.0-4.14.1-4.1-4.1-4.0-4.14.14.1-4.1-4.14.2-4.1-4.14.13.8-4.03.73.7-3.73.82.6
Bone: maximum diameter4.48.19.53.1-3.13.0-3.0-3.0-2.9-3.03.03.0-3.0-2.93.0-3.0-3.02.82.8-2.72.82.5-2.52.51.5
Bone: maximum force12.120.822.84.8-4.74.8-4.7-4.7-4.7-4.74.74.7-4.7-4.64.8-4.7-4.74.74.5-4.44.34.4-4.44.43.2
Bone: maximum moment12.120.822.84.8-4.74.8-4.7-4.7-4.7-4.74.74.7-4.7-4.64.8-4.7-4.64.74.5-4.44.24.3-4.44.33.4
Mean time between licks in bursts0.50.70.9-0.90.9-0.80.90.80.80.9-0.9-0.80.80.9-0.80.90.9-1.0-0.70.7-0.7-0.70.8-0.9-0.8
Mean num. licks in bursts0.20.22.40.3-0.10.1-0.2-0.1-0.1-0.20.20.2-0.2-0.40.1-0.3-0.30.30.7-0.40.70.6-0.60.71.6
Cd content in liver0.40.41.0-0.60.5-0.50.50.50.60.5-0.5-0.60.60.5-0.60.60.6-0.5-0.90.6-1.0-1.01.0-1.0-0.3
Co content in liver0.20.31.3-0.40.5-0.50.50.50.40.5-0.6-0.50.50.6-0.50.50.5-0.5-0.40.5-0.4-0.30.3-0.3-1.1
Cu content in liver1.61.93.21.3-1.31.3-1.3-1.3-1.3-1.31.31.3-1.3-1.41.2-1.4-1.41.31.2-1.41.41.5-1.51.61.8
Fe content in liver0.10.10.3-0.30.4-0.40.40.40.30.4-0.4-0.30.30.4-0.50.30.3-0.5-0.40.3-0.2-0.00.0-0.0-0.0
K content in liver1.71.77.91.2-1.31.2-1.3-1.2-1.2-1.31.31.2-1.2-1.41.2-1.3-1.31.31.0-1.21.00.9-0.90.92.8
Mg content in liver0.20.22.90.2-0.20.2-0.2-0.2-0.1-0.20.20.2-0.1-0.20.1-0.2-0.10.3-0.1-0.0-0.1-0.20.2-0.21.7
Mn content in liver0.20.31.90.4-0.50.4-0.5-0.4-0.4-0.50.50.4-0.5-0.50.4-0.5-0.50.50.1-0.30.30.3-0.40.31.4
Na content in liver0.20.20.90.3-0.50.4-0.5-0.4-0.3-0.50.50.4-0.4-0.50.4-0.5-0.40.40.0-0.40.10.1-0.10.11.0
Rb content in liver0.00.00.2-0.00.1-0.10.10.1-0.00.1-0.1-0.10.10.1-0.00.10.10.0-0.10.3-0.1-0.30.3-0.3-0.4
Se content in liver0.40.51.1-0.60.5-0.60.50.60.60.5-0.5-0.60.60.5-0.70.60.6-0.5-1.00.7-1.0-0.90.9-0.90.7
Sr content in liver0.90.91.01.0-0.90.9-0.9-0.9-1.0-0.90.90.9-0.9-0.91.0-0.9-0.90.91.0-1.01.01.0-1.01.00.3
Zn content in liver0.40.40.5-0.60.6-0.70.60.60.60.6-0.6-0.60.60.6-0.60.60.6-0.6-0.70.7-0.6-0.70.7-0.7-0.4
Bone: minimum diameter7.213.415.84.0-3.93.9-3.9-3.9-3.9-3.83.83.8-3.8-3.73.8-3.8-3.83.83.6-3.63.43.3-3.33.42.0
Time in familiar zone, hab. session 10.20.20.3-0.30.3-0.40.40.40.40.3-0.3-0.40.40.3-0.60.40.4-0.4-0.60.4-0.4-0.50.5-0.50.5
Time in novel zone, hab. session 10.10.11.10.2-0.20.3-0.2-0.3-0.2-0.20.20.3-0.2-0.10.4-0.2-0.20.20.4-0.20.20.2-0.20.2-1.0
Total zone transitions, hab. session 10.30.40.6-0.70.6-0.60.70.60.70.6-0.6-0.60.60.6-0.50.60.6-0.5-0.60.4-0.4-0.60.6-0.8-0.7
Total locomotion distance, hab. session 10.00.00.1-0.30.3-0.20.30.20.30.2-0.2-0.20.20.2-0.10.20.2-0.1-0.1-0.10.0-0.20.2-0.20.1
Locomotion velocity, hab. session 10.00.00.0-0.20.2-0.10.20.10.20.1-0.1-0.10.10.1-0.00.10.1-0.0-0.1-0.20.1-0.20.1-0.10.1
Time in familiar zone, hab. session 20.00.10.50.1-0.20.2-0.2-0.2-0.3-0.10.20.2-0.1-0.10.2-0.1-0.10.3-0.1-0.1-0.30.1-0.10.20.7
Time in novel zone, hab. session 20.10.11.2-0.10.1-0.20.20.10.20.1-0.1-0.10.10.1-0.00.10.1-0.20.10.10.2-0.20.2-0.3-1.1
Total zone transitions, hab. session 20.10.10.4-0.30.2-0.30.30.30.30.2-0.2-0.30.30.2-0.40.30.3-0.2-0.40.2-0.2-0.50.6-0.60.5
Total locomotion distance, hab. session 20.20.30.7-0.40.4-0.40.40.40.50.4-0.4-0.40.50.4-0.60.40.4-0.5-0.60.5-0.5-0.80.9-0.90.0
Locomotion velocity, hab. session 20.10.10.4-0.20.1-0.20.20.20.30.1-0.2-0.20.20.1-0.40.20.2-0.3-0.40.2-0.2-0.60.6-0.60.3
Novel to familiar place preference ratio0.80.91.31.1-1.11.1-1.1-1.1-1.0-1.01.01.0-1.0-0.81.1-1.0-0.90.90.9-0.60.80.6-0.60.8-0.5
Novelty place preference0.40.50.70.8-0.80.8-0.8-0.8-0.7-0.70.70.7-0.7-0.50.8-0.7-0.60.60.6-0.40.50.3-0.40.5-0.8
Time in novel zone, NPP test0.30.31.00.7-0.70.7-0.6-0.7-0.6-0.50.50.6-0.6-0.40.7-0.5-0.50.50.5-0.20.40.3-0.30.4-1.0
Total zone transitions, NPP test0.91.31.8-1.21.2-1.21.21.21.21.1-1.2-1.11.21.1-1.21.21.1-1.1-1.11.0-0.8-1.21.2-1.4-0.1
Total locomotion distance, NPP test2.63.54.5-1.91.9-1.81.91.81.91.8-1.9-1.81.91.8-1.91.91.9-1.8-1.91.7-1.7-2.12.1-2.1-1.3
Locomotion velocity, NPP test1.42.03.0-1.41.4-1.41.41.41.41.4-1.4-1.41.41.3-1.51.41.4-1.4-1.51.3-1.3-1.71.7-1.7-0.8
Intraocular pressure9.813.717.7-3.94.2-4.04.13.93.94.1-4.1-3.93.94.1-3.83.93.9-4.0-3.13.2-3.2-2.72.7-2.7-3.5
Delta distance traveled before/after self-admin0.30.31.90.4-0.20.3-0.3-0.4-0.4-0.40.40.4-0.4-0.50.5-0.4-0.50.51.4-0.80.70.6-0.60.61.0
Delta ambulatory time before/after self-admin0.20.21.60.3-0.10.2-0.2-0.3-0.3-0.30.20.3-0.3-0.40.5-0.3-0.40.51.3-0.80.50.6-0.60.50.7
Parametrial fat weight0.71.42.4-1.21.6-1.51.51.41.41.3-1.4-1.31.31.2-1.41.31.2-1.4-0.60.6-0.5-0.90.9-0.9-0.3
Pavlov. Cond. lever latency0.00.10.20.2-0.30.2-0.2-0.2-0.2-0.30.30.2-0.2-0.30.3-0.2-0.20.30.1-0.10.0-0.30.3-0.1-0.4
Pavlov. Cond. magazine entry latency0.00.00.2-0.20.2-0.10.10.10.20.2-0.1-0.10.10.1-0.30.10.1-0.30.20.00.20.4-0.40.10.4
Pavlov. Cond. change in total contacts0.00.00.5-0.0-0.00.0-0.0-0.0-0.10.0-0.00.0-0.00.0-0.00.00.00.0-0.1-0.0-0.10.2-0.2-0.10.7
Pavlov. Cond. index score0.10.20.80.2-0.20.3-0.3-0.3-0.3-0.20.20.3-0.3-0.20.2-0.3-0.30.10.5-0.40.60.9-0.80.50.6
Pavlov. Cond. latency score0.10.10.60.1-0.10.2-0.1-0.2-0.1-0.10.10.2-0.2-0.10.0-0.2-0.20.00.4-0.30.50.8-0.70.40.5
Pavlov. Cond. lever contacts0.30.30.5-0.70.7-0.60.70.60.60.7-0.7-0.60.60.7-0.60.70.6-0.7-0.50.5-0.5-0.20.2-0.40.0
Pavlov. Cond. magazine entry number0.00.00.20.2-0.20.1-0.1-0.1-0.1-0.10.10.1-0.1-0.10.2-0.1-0.00.3-0.30.1-0.3-0.50.4-0.2-0.3
Pavlov. Cond. intertrial magazine entries0.50.61.4-0.60.7-0.70.70.80.60.7-0.7-0.80.80.7-0.80.80.8-0.6-1.00.8-1.0-1.21.2-1.00.1
Pavlov. Cond. lever-magazine prob. diff.0.50.61.60.6-0.60.7-0.6-0.7-0.6-0.60.60.7-0.7-0.60.5-0.7-0.70.50.9-0.81.01.3-1.31.01.0
Pavlov. Cond. response bias0.10.10.2-0.40.4-0.30.30.30.30.3-0.3-0.20.30.3-0.40.30.2-0.50.00.10.00.3-0.30.10.4
Pavlov. Cond. lever latency0.00.00.10.2-0.40.3-0.3-0.2-0.2-0.30.30.2-0.2-0.30.1-0.2-0.20.2-0.00.2-0.2-0.10.1-0.00.2
Pavlov. Cond. magazine entry latency0.20.20.40.6-0.60.6-0.6-0.6-0.6-0.50.50.5-0.5-0.40.5-0.5-0.50.50.2-0.40.40.4-0.40.30.2
Pavlov. Cond. change in total contacts0.81.01.41.2-1.01.1-1.0-1.1-1.2-1.01.01.0-1.0-0.91.1-1.0-1.01.10.8-1.21.01.0-1.00.91.0
Pavlov. Cond. index score0.10.20.30.4-0.30.4-0.3-0.4-0.4-0.30.30.4-0.4-0.30.4-0.3-0.30.40.3-0.60.50.4-0.40.40.2
Pavlov. Cond. latency score0.20.20.40.6-0.40.5-0.5-0.5-0.5-0.40.40.5-0.5-0.40.5-0.4-0.40.50.4-0.60.60.5-0.50.50.2
Pavlov. Cond. lever contacts0.20.30.5-0.60.7-0.60.70.60.60.7-0.7-0.60.60.6-0.50.60.6-0.5-0.40.2-0.3-0.40.4-0.4-0.2
Pavlov. Cond. magazine entry number1.01.21.7-1.31.2-1.31.21.31.21.2-1.2-1.21.21.1-1.11.11.1-1.2-0.71.1-0.9-0.90.9-0.9-0.4
Pavlov. Cond. intertrial magazine entries2.12.74.2-2.01.9-1.91.91.91.91.8-1.8-1.81.71.6-1.81.71.6-1.9-0.91.5-1.3-1.31.3-1.2-0.4
Pavlov. Cond. lever-magazine prob. diff.0.30.40.60.7-0.50.6-0.6-0.7-0.6-0.50.50.6-0.6-0.50.7-0.6-0.60.70.5-0.80.70.6-0.60.60.3
Pavlov. Cond. response bias0.10.20.2-0.40.5-0.40.50.40.40.5-0.5-0.40.40.5-0.30.50.4-0.3-0.40.1-0.3-0.30.3-0.4-0.2
Time in closed arm before self-admin0.70.81.61.1-1.21.1-1.1-1.1-1.0-1.11.11.0-1.0-1.01.3-1.0-0.91.10.8-0.60.4-0.20.2-0.1-0.4
Time in closed arm after self-admin0.20.20.60.6-0.70.7-0.7-0.6-0.5-0.60.60.5-0.5-0.50.1-0.5-0.4-0.00.0-0.0-0.4-0.50.5-0.5-0.4
Time in open arm before self-admin0.70.81.41.1-1.21.1-1.1-1.1-1.0-1.11.01.0-1.0-1.00.6-1.0-0.90.60.7-0.70.70.4-0.40.50.2
Time in open arm after self-admin0.30.30.9-0.50.4-0.50.40.50.40.5-0.5-0.50.50.6-0.40.50.5-0.4-0.70.8-0.1-0.50.5-0.5-0.9
Bone: periosteal estimation11.223.125.65.1-5.05.0-5.0-5.0-5.0-5.04.95.0-5.0-4.95.0-5.0-4.94.94.8-4.84.64.5-4.54.53.2
Bone: periosteal perimeter10.317.218.94.2-4.44.3-4.3-4.3-4.2-4.34.34.3-4.3-4.34.2-4.3-4.34.24.1-4.23.93.8-3.83.83.0
Bone: post-yield work8.411.412.83.2-3.43.4-3.4-3.4-3.4-3.43.53.4-3.5-3.43.6-3.5-3.53.43.6-3.33.43.5-3.53.51.9
Progressive ratio test 1 active lever presses2.82.93.9-1.92.0-1.91.91.91.92.0-1.9-1.91.81.9-1.71.91.8-1.6-1.91.6-1.4-0.90.9-1.0-1.4
Progressive ratio test 1 breakpoint2.72.83.8-1.71.8-1.81.81.81.81.8-1.8-1.81.81.9-1.71.81.8-1.6-1.91.7-1.5-1.11.1-1.2-1.5
Progressive ratio test 1 inactive lever presses2.52.74.1-1.71.4-1.51.51.51.81.5-1.5-1.61.61.5-1.81.61.6-1.8-2.01.7-1.9-1.81.8-1.7-1.3
Progressive ratio test 2 active lever presses1.51.62.4-1.31.3-1.31.31.31.31.3-1.2-1.31.31.4-1.11.31.3-1.1-1.51.4-1.4-0.90.9-0.9-1.0
Progressive ratio test 2 breakpoint1.92.23.1-1.51.6-1.61.51.61.51.6-1.5-1.61.51.7-1.31.51.6-1.4-1.81.6-1.5-1.01.0-1.0-1.2
Progressive ratio test 2 inactive lever presses2.83.24.6-1.71.7-1.81.81.81.81.8-1.8-1.81.81.9-1.81.81.8-1.9-2.11.9-2.0-1.71.7-1.7-1.3
Incentive Sensitization - Responses0.10.10.20.3-0.40.3-0.4-0.3-0.2-0.30.30.2-0.2-0.20.1-0.2-0.2-0.1-0.40.2-0.30.0-0.00.1-0.1
Incentive Sensitization - Breakpoint0.10.10.40.1-0.20.2-0.2-0.1-0.1-0.10.20.0-0.10.0-0.2-0.1-0.0-0.3-0.60.4-0.4-0.10.00.0-0.4
Sum of active levers in priming session hrs 5-60.10.10.3-0.50.5-0.40.40.40.40.5-0.3-0.40.40.4-0.30.30.3-0.1-0.10.20.00.4-0.40.4-0.3
Progressive ratio0.10.11.00.1-0.10.1-0.1-0.0-0.2-0.10.10.1-0.1-0.10.6-0.1-0.10.7-0.3-0.1-0.30.2-0.20.21.0
Food seeking constrained by brief footshock0.20.21.10.00.1-0.00.0-0.0-0.1-0.00.00.1-0.2-0.20.3-0.2-0.20.10.7-0.71.00.9-0.90.90.6
Seeking ratio, punishment vs. effort0.10.10.70.00.00.00.0-0.10.0-0.00.00.1-0.1-0.1-0.2-0.1-0.1-0.40.7-0.30.90.3-0.30.4-0.6
Retroperitoneal fat weight0.10.22.3-0.40.4-0.40.40.40.40.3-0.2-0.30.30.1-0.40.20.2-0.1-0.2-0.00.20.1-0.10.21.5
Reaction time number correct0.50.71.90.8-0.70.8-0.7-0.8-0.9-0.80.90.8-0.8-0.90.6-0.8-0.80.51.4-0.91.00.6-0.60.80.7
Reaction time mean minus median8.511.214.2-3.53.5-3.53.43.53.43.6-3.6-3.53.53.5-3.83.43.4-3.6-3.43.4-3.0-2.72.7-2.8-2.6
Reaction time mean minus median AUC6.17.910.5-2.93.0-3.02.93.02.93.1-3.1-3.02.93.0-3.22.92.9-3.1-2.72.9-2.4-2.12.0-2.0-2.2
Reaction time num false alarms2.02.74.3-1.61.5-1.61.61.61.71.5-1.5-1.61.61.5-1.71.61.6-1.4-1.51.7-1.5-2.12.1-2.0-0.9
Reaction time num false alarms AUC3.24.45.6-2.12.1-2.12.12.12.22.1-2.1-2.12.12.0-2.22.12.1-2.0-2.02.2-1.9-2.42.4-2.2-1.2
Reaction time trials correct on left0.50.71.90.8-0.70.8-0.7-0.8-0.9-0.80.90.8-0.8-0.90.6-0.8-0.80.51.4-0.91.00.6-0.60.80.7
Reaction time trials on left0.30.41.50.7-0.60.6-0.6-0.6-0.7-0.60.70.7-0.6-0.70.4-0.6-0.70.31.2-0.80.90.5-0.50.60.6
Reaction time mean0.60.81.4-1.01.2-1.01.01.10.91.2-1.2-1.01.01.1-1.11.00.9-0.9-0.80.7-0.20.1-0.10.0-0.9
Reaction time mean AUC0.40.50.9-0.80.9-0.80.80.80.70.9-0.9-0.80.70.8-0.90.70.7-0.6-0.60.40.10.3-0.40.4-0.6
Median of all reaction times0.10.21.0-0.10.2-0.00.00.0-0.10.2-0.10.0-0.00.10.1-0.0-0.10.20.2-0.30.81.0-1.00.9-0.2
Reaction time omissions8.411.514.5-3.83.7-3.73.63.73.83.8-3.6-3.73.63.6-3.73.63.5-3.4-3.53.4-2.7-2.32.3-2.2-2.7
Reaction time false alarm rate2.33.34.3-1.81.7-1.81.81.81.91.8-1.8-1.81.81.8-1.81.81.8-1.5-2.12.0-1.7-2.02.0-1.9-1.0
Reaction time premature initiation rate3.14.26.0-2.52.4-2.42.42.32.32.3-2.2-2.22.22.1-1.72.22.2-1.9-1.61.9-1.3-1.71.7-1.5-1.1
Reaction time premature initiations1.82.63.8-1.92.0-1.91.91.81.81.8-1.7-1.81.71.7-1.51.71.7-1.6-1.01.4-0.9-1.41.3-1.0-0.8
Std. dev. reaction times6.18.511.5-3.03.1-3.13.03.13.03.2-3.2-3.13.13.1-3.43.03.0-3.1-2.93.0-2.3-2.02.0-2.0-2.7
Reaction time trials completed0.30.41.50.7-0.60.6-0.6-0.6-0.7-0.60.70.7-0.6-0.70.4-0.6-0.70.31.2-0.80.90.5-0.50.60.6
Reaction time trials AUC0.71.02.41.1-0.91.0-0.9-1.0-1.0-1.01.11.0-1.0-1.10.8-1.0-1.00.71.6-1.11.20.7-0.70.80.8
Run reversals in cocaine runway, females0.60.63.3-0.50.5-0.50.40.50.60.6-0.6-0.60.60.7-0.80.60.6-0.7-0.90.9-1.3-0.60.6-0.7-1.8
Run reversals in cocaine runway, males1.41.32.2-1.31.0-1.01.01.01.41.0-1.0-1.11.01.0-1.31.01.0-1.4-1.01.3-1.2-1.11.1-1.1-1.5
Latency to leave start box in cocaine runway0.00.00.1-0.10.0-0.10.10.10.10.0-0.1-0.10.10.10.20.10.10.1-0.10.2-0.2-0.40.4-0.2-0.3
Latency to leave start box in cocaine runway, F1.92.03.4-1.51.4-1.41.41.41.51.4-1.3-1.41.41.5-1.31.41.4-1.4-1.41.5-1.4-1.31.3-1.2-1.8
Latency to leave start box in cocaine runway, M2.52.43.91.6-1.51.5-1.5-1.5-1.7-1.61.51.5-1.5-1.61.8-1.5-1.51.81.6-1.61.61.2-1.21.22.0
Std. dev. time between licks in bursts1.01.13.5-1.11.3-1.21.21.11.11.2-1.2-1.11.11.2-1.11.11.1-1.2-0.50.9-0.5-0.30.3-0.4-1.9
Total sessions with >9 infusions0.40.40.9-0.50.6-0.60.60.60.60.6-0.6-0.60.60.7-0.70.60.7-0.5-0.90.7-0.7-0.70.7-0.7-0.2
Short access day 1 total inactive lever presses0.50.61.0-1.01.0-1.01.00.91.00.9-0.9-0.90.90.8-0.70.90.8-0.7-0.40.5-0.5-0.50.5-0.4-0.2
Short access day 10 total inactive lever presses0.30.30.6-0.80.6-0.60.60.60.70.6-0.6-0.60.50.5-0.20.50.5-0.4-0.20.4-0.3-0.30.3-0.3-0.8
Short access day 1 total infusions0.10.10.20.2-0.30.3-0.3-0.2-0.1-0.20.20.2-0.2-0.2-0.1-0.2-0.10.1-0.50.2-0.2-0.20.20.00.5
Short access day 10 total infusions0.80.82.4-0.70.7-0.80.80.80.70.7-0.7-0.80.80.7-0.60.80.8-0.5-1.00.9-1.2-1.51.5-1.50.8
Short access total infusions0.20.20.4-0.30.3-0.30.40.40.30.4-0.3-0.40.40.4-0.40.40.4-0.3-0.60.5-0.5-0.60.6-0.40.2
Short access day 1 locomotion0.30.31.70.2-0.30.2-0.2-0.10.1-0.10.10.00.00.0-0.30.00.1-0.2-0.50.7-0.8-1.21.2-1.1-1.3
Short access day 10 total locomotion0.30.41.8-0.40.3-0.30.40.20.30.3-0.4-0.30.40.40.10.40.50.1-0.40.4-0.7-1.31.3-1.3-1.0
Short access total locomotion0.40.41.7-0.40.3-0.30.40.30.40.3-0.3-0.30.40.4-0.10.40.5-0.1-0.40.5-0.7-1.31.3-1.3-0.8
One hour access (0.3 mA shock)0.20.20.8-0.50.3-0.40.30.40.50.4-0.2-0.40.40.4-0.50.40.4-0.4-0.90.7-0.7-0.30.3-0.3-0.1
Compulsive drug intake0.50.51.30.8-0.70.7-0.8-0.7-0.7-0.80.80.7-0.7-0.70.4-0.7-0.70.50.5-0.80.60.6-0.60.61.1
One hour access (shock baseline)0.00.00.3-0.1-0.10.0-0.10.10.10.10.1-0.10.10.1-0.20.10.1-0.2-0.50.5-0.4-0.10.0-0.0-0.4
Social response proportion0.91.03.4-0.80.7-0.70.70.80.80.8-0.8-0.80.80.9-1.20.80.9-1.1-1.61.1-1.8-1.01.0-0.9-0.5
Social responses9.111.715.3-3.53.2-3.33.33.43.53.3-3.3-3.43.43.4-3.73.43.4-3.5-3.93.7-3.9-3.33.3-3.0-3.2
Social time1.01.33.1-0.80.9-0.90.81.00.91.1-1.1-1.01.11.2-1.41.11.1-1.2-1.81.5-1.4-1.21.2-1.2-1.0
Soleus weight1.13.44.21.8-1.81.8-1.8-1.8-1.6-1.91.81.8-1.9-1.92.0-1.9-1.92.02.0-1.92.01.8-1.81.81.5
Bone: stiffness14.522.825.75.1-5.05.0-5.0-5.0-5.0-5.05.05.0-5.0-4.94.8-4.9-4.94.84.5-4.74.44.5-4.54.53.4
Tibialis anterior weight2.58.610.93.0-3.23.0-3.1-3.1-2.9-3.23.13.0-3.1-3.13.3-3.1-3.03.22.8-2.92.72.6-2.62.61.9
Time to tail flick, vehicle, before self-admin1.01.01.7-1.21.2-1.11.11.11.31.2-1.1-1.11.01.1-1.31.01.0-1.3-1.10.8-0.6-0.20.10.1-1.1
Time to tail flick, vehicle, after self-admin0.10.11.70.2-0.20.2-0.2-0.1-0.1-0.00.10.0-0.00.1-0.0-0.00.0-0.2-0.40.4-0.2-0.10.1-0.2-1.3
Time to tail flick, test, before self-admin1.00.92.5-0.90.6-0.70.70.80.80.8-0.7-0.90.80.9-1.00.80.9-0.9-1.41.3-1.6-1.11.1-1.0-1.1
Time to tail flick, test, after self-admin0.10.10.30.4-0.60.4-0.5-0.3-0.3-0.40.40.3-0.3-0.40.1-0.3-0.3-0.0-0.00.2-0.3-0.30.3-0.3-0.5
Delta time to tail flick, vehicle, before/after SA0.20.20.40.6-0.50.5-0.5-0.5-0.6-0.40.40.5-0.5-0.40.6-0.4-0.40.50.4-0.40.40.5-0.50.30.4
Delta time to tail flick, test, before/after SA0.30.30.50.7-0.70.6-0.6-0.6-0.6-0.70.60.6-0.6-0.70.6-0.6-0.60.40.7-0.40.70.1-0.10.00.1
Tibia length5.816.419.24.4-4.04.2-4.1-4.2-4.3-4.04.14.2-4.1-3.94.1-4.1-4.14.03.9-4.23.94.1-4.14.12.8
Ambulatory time before self-admin3.63.74.9-2.02.0-2.02.02.01.92.0-2.1-2.02.02.1-1.82.02.0-1.8-2.22.0-1.6-1.71.7-1.7-1.5
Ambulatory time after self-admin0.91.02.2-1.21.5-1.31.41.21.21.3-1.3-1.11.11.2-0.61.11.0-0.8-0.10.5-0.00.0-0.10.0-0.7
Bone: tissue strength0.30.30.60.5-0.50.6-0.5-0.6-0.6-0.50.50.6-0.6-0.50.6-0.5-0.50.60.5-0.70.60.7-0.70.70.1
Total heroin consumption2.63.04.21.6-1.71.8-1.7-1.8-1.6-1.81.81.8-1.8-1.71.9-1.8-1.81.72.1-1.82.01.6-1.71.80.1
Bone: trabecular number4.06.27.02.5-2.52.6-2.6-2.5-2.6-2.52.62.5-2.5-2.52.4-2.5-2.52.52.3-2.42.22.4-2.42.52.7
Bone: trabecular spacing1.01.32.7-1.11.2-1.21.21.21.21.2-1.2-1.21.21.2-1.01.21.2-1.2-1.01.2-0.8-1.01.1-1.1-1.6
Bone: trabecular thickness0.40.50.9-0.60.6-0.60.60.60.50.7-0.7-0.70.70.7-0.70.70.7-0.6-0.90.8-1.0-0.90.9-0.80.2
Bone: trabecular tissue density0.10.10.3-0.40.4-0.40.40.30.40.4-0.4-0.40.40.4-0.20.40.4-0.3-0.40.3-0.4-0.40.4-0.5-0.3
Water consumed over 24 hours0.20.20.60.5-0.40.4-0.4-0.4-0.3-0.50.40.4-0.4-0.50.6-0.5-0.50.50.5-0.50.60.5-0.50.50.8
Number of responses in last shaping day0.50.50.80.7-0.90.8-0.7-0.8-0.7-0.80.90.6-0.6-0.70.7-0.6-0.50.80.1-0.2-0.4-0.90.9-0.80.4